For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2538 | - | - | 100% (326) | ABC transporter related |
| M. thermoresistible (build 8) | TH_4520 | - | 3e-39 | 38.29% (269) | PUTATIVE osmoprotectant (glycine |
| M. thermoresistible (build 8) | TH_2424 | - | 6e-39 | 38.63% (233) | PUTATIVE sulfate ABC transporter, ATPase subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 8e-41 | 37.13% (307) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_3165 | - | 9e-40 | 43.53% (232) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 8e-41 | 37.13% (307) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01122 | - | 6e-39 | 39.38% (259) | putative ABC transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2803c | - | 3e-58 | 48.95% (237) | methionine import ATP-binding protein metN |
| M. marinum M | MMAR_3715 | cysA1 | 5e-40 | 36.81% (307) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 1e-38 | 36.09% (302) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. smegmatis MC2 155 | MSMEG_5807 | - | 1e-76 | 60.71% (252) | D-methionine transport ATP-binding protein MetN |
| M. ulcerans Agy99 | MUL_4001 | oppD | 9e-40 | 38.64% (264) | oligopeptide-transport ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_3884 | - | 2e-74 | 58.47% (248) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 ------MT--------YAIVVADATKRYG----DFVALDHVDFVVPTGSL
Rv2397c|M.tuberculosis_H37Rv ------MT--------YAIVVADATKRYG----DFVALDHVDFVVPTGSL
MMAR_3715|M.marinum_M MKKETSLTGPGT--GGHAIVVRDAFKQYG----DFVALDHVDFVVPAGSL
MAV_1785|M.avium_104 ------MTDAGTDRGDIAITVRDAYKRYG----DFVALDHVDFVVPTGSL
Mflv_3165|M.gilvum_PYR-GCK MSELITEAAASEPAGTVKIRIEGLKKSFG----DLVVLDGIDTTVSHGEV
MSMEG_5807|M.smegmatis_MC2_155 -----------------MIEIENLTKRFG----DRTVLDEVSLSVAAGEI
Mvan_3884|M.vanbaalenii_PYR-1 --MLRVTAGPSTVESFPVIEIENLTKRFG----DRTVLDDISLSVGSGEI
TH_2538|M.thermoresistible__bu -----------------MIELTDLTKVYGCGEHRTVVLDRINFRVETGEV
MAB_2803c|M.abscessus_ATCC_199 -----------MGDVAPLIQFQNVTKTFRVGKKTVTAVDDVSLDIGSGDV
MLBr_01122|M.leprae_Br4923 --------------MSPLLEVTDLAVTFETNGEPVTAVRGISYRINAGEV
MUL_4001|M.ulcerans_Agy99 --------------MNPLLEVTDLAVTFPTENDPVTAVRGISYQVAPGEV
: . . : ..: :. : *.:
Mb2419c|M.bovis_AF2122/97 TALLGPSGSGKSTLLRTIAGLD---QPDTGTITINGRDVTR-----VPPQ
Rv2397c|M.tuberculosis_H37Rv TALLGPSGSGKSTLLRTIAGLD---QPDTGTITINGRDVTR-----VPPQ
MMAR_3715|M.marinum_M TALLGPSGSGKSTLLRTIAGLD---QPDSGNITINGRDVTR-----VPPQ
MAV_1785|M.avium_104 TALLGPSGSGKSTLLRTIAGLD---QPDTGTVTIYGRDVTR-----VPPQ
Mflv_3165|M.gilvum_PYR-GCK VCVIGPSGSGKSTFLRCLNKLE---DITGGRVVVDEFDLTDP-KIDLDKV
MSMEG_5807|M.smegmatis_MC2_155 LAVVGPSGAGKSTLSRCVSALE---RPTSGTVRVDGKDFSRLDGTELIAA
Mvan_3884|M.vanbaalenii_PYR-1 LAVVGPSGAGKSTLSRCVSFLE---RPTSGTVRVDGKDFTRLDGDELLAA
TH_2538|M.thermoresistible__bu LAVVGPSGAGKSTLAQCINLLT---RPTSGSVVVNGEDLTTLSTHRLRVA
MAB_2803c|M.abscessus_ATCC_199 FAMIGYSGAGKSTLVRLINGLE---RPTSGRVIVDGAEVSALGERELRGL
MLBr_01122|M.leprae_Br4923 VAMVGESGSGKSAAAMAVVGLLPEYAQVRGSVRLHNTELVGLADKTMSRF
MUL_4001|M.ulcerans_Agy99 VAVVGESGSGKSAAAMAVVGLLPEYAKVRGSVRLQGTELLGLADDAMSRF
.::* **:***: : * * : : :. :
Mb2419c|M.bovis_AF2122/97 R-RGIGFVFQH--YAAFKHLTVRDNVAFG--LKIRKRPKAEIKAKVDNLL
Rv2397c|M.tuberculosis_H37Rv R-RGIGFVFQH--YAAFKHLTVRDNVAFG--LKIRKRPKAEIKAKVDNLL
MMAR_3715|M.marinum_M R-RGIGFVFQH--YAAFKHLTVRDNVAYG--LKIRKRPKAEIRDKVDNLL
MAV_1785|M.avium_104 R-RGIGFVFQH--YAAFKHLTVRDNVAYG--LKVRKRPKAEIKAKVDNLL
Mflv_3165|M.gilvum_PYR-GCK R-QHIGMVFQH--FNLFPHMTVLENVTLAP-LLTKKMDKAAAEKKALQLL
MSMEG_5807|M.smegmatis_MC2_155 R-RGVGVIFQS--APLLRRRTVARNIALP--LEYLGATQSSIDKRVSELL
Mvan_3884|M.vanbaalenii_PYR-1 R-RNVGVIFQT--APLLRRRTVAQNIALP--LQYLHATEGSAGTRVTELL
TH_2538|M.thermoresistible__bu R-RRIGTVFQS--SGLLERRTAAENVALP--LEYLGVTAAETRKRVAELL
MAB_2803c|M.abscessus_ATCC_199 R-SDIGMIFQQ--FNLFRSRTVAGNIAYP--LRVAGWTADKRNARVAELL
MLBr_01122|M.leprae_Br4923 RGKAIGTVFQDPMSALTPVYTVGDQITEAIKVHQPRVGKKAAHRRAVELL
MUL_4001|M.ulcerans_Agy99 RGKVIGTVFQDPMSALTPVYTVGDQIAETIEIHQPTFSRKAARRRAVELL
* :* :** *. ::: : :. :**
Mb2419c|M.bovis_AF2122/97 QVVGLSG---FQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALD
Rv2397c|M.tuberculosis_H37Rv QVVGLSG---FQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALD
MMAR_3715|M.marinum_M EVVGLSG---FHGRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALD
MAV_1785|M.avium_104 EVVGLSG---FQGRYPNQLSGGQRQRMALARALAVDPQVLLLDEPFGALD
Mflv_3165|M.gilvum_PYR-GCK DQVGLAE---KAGVKPATLSGGQKQRVAIARALAMNPSIMLFDEATSALD
MSMEG_5807|M.smegmatis_MC2_155 ERVGLTD---RASYLPAQLSGGQKQRVGIARALALGPSNLLSDEATSGLD
Mvan_3884|M.vanbaalenii_PYR-1 DRVGLAD---RRDFYPAQLSGGQKQRVGIARALALGPSNLLSDEATSGLD
TH_2538|M.thermoresistible__bu DRVGLAA---RANHYPFQLSGGQRQRVGIARALALRPSVLLSDEATAGLD
MAB_2803c|M.abscessus_ATCC_199 EFVGLGD---KAKSYPDQLSGGQKQRVGIARALATSPSVLLADEATSALD
MLBr_01122|M.leprae_Br4923 ELVGITQPDRRARAFPHELSGGERQRVVIATAIANDPDLLICDEPTTALD
MUL_4001|M.ulcerans_Agy99 ELVGIAQPERRARAFPHELSGGERQRVVIAIAIANDPDLLICDEPTTALD
: **: * ****::**: :* *:* *. :: **. .**
Mb2419c|M.bovis_AF2122/97 AKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQV
Rv2397c|M.tuberculosis_H37Rv AKVREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQV
MMAR_3715|M.marinum_M AKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQV
MAV_1785|M.avium_104 AKVREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNQGRIEQI
Mflv_3165|M.gilvum_PYR-GCK PEMVGDVLEVLRTLARGG-MTMVVVTHEMGFAREVASRVIFMADGHIVEE
MSMEG_5807|M.smegmatis_MC2_155 PATTKSILELLSHLRDEYALSIILITHEMEVVREIADSVARLDGGRIIES
Mvan_3884|M.vanbaalenii_PYR-1 PATTRSILALLSHLRDEFGLSIILITHEMEVVREIADSVARIEDGRIIES
TH_2538|M.thermoresistible__bu PTTTASVVELLRELRDDLNLSIVFITHEMDTVLKIADSVARLDHGRIVEA
MAB_2803c|M.abscessus_ATCC_199 PETTSDVLRLLREVNAEFGVTIVVITHEMDVVRTVADHVAVLADGKVVET
MLBr_01122|M.leprae_Br4923 VTVQAQILEVLKTARDVTGAGVLIITHDLGVVTEFADQALVMYAGRVVES
MUL_4001|M.ulcerans_Agy99 VTVQAQILDVLKTARDVTGAGVLIITHDLGVVAEFADRALVMYAGRVVEK
.: * :.:**: . .*. : *:: :
Mb2419c|M.bovis_AF2122/97 GSPTDVYDAPANAFVMSFLGAVSTLNGSLVR-----PHDIRVGRTPNMAV
Rv2397c|M.tuberculosis_H37Rv GSPTDVYDAPANAFVMSFLGAVSTLNGSLVR-----PHDIRVGRTPNMAV
MMAR_3715|M.marinum_M GSPTEVYDAPANAFVMSFLGAVSALNGALVR-----PHDIRVGRTPEMAV
MAV_1785|M.avium_104 GSPTEVYDAPTNAFVMSFLGAVSTLNGTLVR-----PHDIRVGRTPEMAV
Mflv_3165|M.gilvum_PYR-GCK GPPAEIFDNPKHPRLQEFLSKVL---------------------------
MSMEG_5807|M.smegmatis_MC2_155 GRVDDIILDPDSTLARELLPDRPGALAPGAG--EVWEVS---YASREVPL
Mvan_3884|M.vanbaalenii_PYR-1 GSVQDVILDPASELARELLPDRPSVPLDGAG--EIWEVS---HASRTVPL
TH_2538|M.thermoresistible__bu GRLVDLLTDPASALGADLRPQGAAAPPAPPXXXRLRGVAGPDHPHRTGAV
MAB_2803c|M.abscessus_ATCC_199 GTVFDVFSTPQSEAGKRFVGTVLRNTPSGED---IARIAQR-HKGRIVAV
MLBr_01122|M.leprae_Br4923 AQVSTLYRERQMPYTVGLLGSVPRLDATQGTRLVPIPGAPPSLAGLQQEC
MUL_4001|M.ulcerans_Agy99 ATVNDLYHNRRMPYTIGLLGSVPRLDATQGTRLVPIPGAPPSPAGLDRGC
. : :
Mb2419c|M.bovis_AF2122/97 AAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAE
Rv2397c|M.tuberculosis_H37Rv AAADGTAGSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAE
MMAR_3715|M.marinum_M AAADGTGESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAE
MAV_1785|M.avium_104 AAEDGTAESTGVARAIVDRVVKLGFEVRVELTSAATGGPFTAQITRGDAE
Mflv_3165|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5807|M.smegmatis_MC2_155 DWLTSIQSAPGLG-----DAKISVLSASIEAIRGVAVGRATLSI---EPA
Mvan_3884|M.vanbaalenii_PYR-1 DWLTSIQSAPGLS-----GAAVSVLSASVESIRGVAVGRAVLAI---TPS
TH_2538|M.thermoresistible__bu RAAGRTGPAAARR-----CGGGTAVDAGSDRRVADRAGRRPGRR---DDA
MAB_2803c|M.abscessus_ATCC_199 EISEGVQIGPALARATELGVRFEVVYGGITTLQSRSFGNLTLELEGPDDQ
MLBr_01122|M.leprae_Br4923 PFAPRCPLVVDECRLREPELVEVRAGHRTACIRTDQVSGRSAADIYGINT
MUL_4001|M.ulcerans_Agy99 PFAPRCPLVIDECRSDEPELIEVGQNHRAACIRTDQVNGRSAADIYGVQT
Mb2419c|M.bovis_AF2122/97 ALALREGDTVYVRATRVPPIAG---GVSGVDDAGVERVKVTST-------
Rv2397c|M.tuberculosis_H37Rv ALALREGDTVYVRATRVPPIAG---GVSGVDDAGVERVKVTST-------
MMAR_3715|M.marinum_M ALALQEGDTVYVRATRVPPIAG---AAPAVPDDGAGSTPSAAQIGVGGQ-
MAV_1785|M.avium_104 ALALREGDTVYVRATRVPPITAGATTVPAVSRDGADEATLTSA-------
Mflv_3165|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5807|M.smegmatis_MC2_155 APT---------RLRRAPA-------------------------------
Mvan_3884|M.vanbaalenii_PYR-1 APSGFVEYLTERGLHVRPVEKVAAGSAEAAA-------------------
TH_2538|M.thermoresistible__bu VAAP----------RRRPIRP-----------------------------
MAB_2803c|M.abscessus_ATCC_199 VAHVVS-----DLSAVTTVQRVAR--------------------------
MLBr_01122|M.leprae_Br4923 DTRTSATSDSSVVVRVRDLVKTYRLTKGVGLRRAIGEIRAVNGVSFELQQ
MUL_4001|M.ulcerans_Agy99 EATEPAPADSSVVVRVSDLVKTYPLTKGVLLRRSIGEVRAVDGVSFELRQ
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3715|M.marinum_M --------------------------------------------------
MAV_1785|M.avium_104 --------------------------------------------------
Mflv_3165|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5807|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3884|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2538|M.thermoresistible__bu --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01122|M.leprae_Br4923 GRTLGIVGESGSGKSTTLHEILRLAVPQSGSIEVLGIDVATLNRASRRSM
MUL_4001|M.ulcerans_Agy99 GHTLGIVGESGSGKSTTLHQILELAAPQSGSIEVLGTDVTTLTASSRRAL
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3715|M.marinum_M --------------------------------------------------
MAV_1785|M.avium_104 --------------------------------------------------
Mflv_3165|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5807|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3884|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2538|M.thermoresistible__bu --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01122|M.leprae_Br4923 RRNIQVVFQDPVASLDPRLPVFELIAEPLHANGFSKNYTQMRVAELLDIV
MUL_4001|M.ulcerans_Agy99 RRDIQVVFQDPVASLDPRLPISDLLAEPLQANGFNKTDTQDRVAELLDIV
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3715|M.marinum_M --------------------------------------------------
MAV_1785|M.avium_104 --------------------------------------------------
Mflv_3165|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5807|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3884|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2538|M.thermoresistible__bu --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01122|M.leprae_Br4923 GLRRDDATRYPTEFSGGQKQRIGIARALALQPKILAFDEPVSALDVSIQA
MUL_4001|M.ulcerans_Agy99 GLRRSDASRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQA
Mb2419c|M.bovis_AF2122/97 --------------------------------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3715|M.marinum_M --------------------------------------------------
MAV_1785|M.avium_104 --------------------------------------------------
Mflv_3165|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5807|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3884|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2538|M.thermoresistible__bu --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01122|M.leprae_Br4923 GIINLLLDLQDRLGLSYLFVSHDLSVIKHLAHQVAVMLAGTIVEQGDSHD
MUL_4001|M.ulcerans_Agy99 GIINLLLDLQAGFKLSYLFVSHDLSVVKHLANSVVVMFAGSIVEQGNSQE
Mb2419c|M.bovis_AF2122/97 --------------------------
Rv2397c|M.tuberculosis_H37Rv --------------------------
MMAR_3715|M.marinum_M --------------------------
MAV_1785|M.avium_104 --------------------------
Mflv_3165|M.gilvum_PYR-GCK --------------------------
MSMEG_5807|M.smegmatis_MC2_155 --------------------------
Mvan_3884|M.vanbaalenii_PYR-1 --------------------------
TH_2538|M.thermoresistible__bu --------------------------
MAB_2803c|M.abscessus_ATCC_199 --------------------------
MLBr_01122|M.leprae_Br4923 VFRNPQHDYTRRLLGAIPRPEVG---
MUL_4001|M.ulcerans_Agy99 VFSNPQHEYTQRLLGAVPQPIPGNAD