For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MLTAVLGIFIGFLVVLAITALTGYFVAQEFAYMAVDRSRLKARAEAGDGASARALTVTRRTSFMLSGAQL GITVTGLLVGYVAEPLIGRGLEILLGGAGIPTVIAVAVGGLFAIAVSTVVQMLFGELFPKNLAIARPEPL ARWLAWSTTLYLKVFGWLIWLFDQSSNLLLRALRIEPVHDVEHSATVRDLEHIVAASREAGEIPAELSAL LDRILDFPTSTAEHAMIPRSRVDTVPAGESISSVLQRMATGHTRYPVIGSSPDDIVGVVELHDLLGPVPA TDTAGAHCRSAVVVPETLPLPNVVRELQRADAEMAIVIDEYGGFAGIVTIEDLAEELVGEIDDEHDTDAE ADVVADGVGWLLAGDLPLDEAERTLDLVLPPGDYETVAGMVIAHAVGLPAVGDEVVIALPADPADLLGDG VPPIRSLTAQVRSIERRVPASVFVTVSEGTGHE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3860 | - | - | 100% (453) | hypothetical protein Mvan_3860 |
| M. vanbaalenii PYR-1 | Mvan_3094 | - | 4e-71 | 36.64% (434) | hypothetical protein Mvan_3094 |
| M. vanbaalenii PYR-1 | Mvan_3095 | - | 4e-42 | 30.86% (350) | hypothetical protein Mvan_3095 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1873c | - | 3e-64 | 36.03% (433) | hypothetical protein Mb1873c |
| M. gilvum PYR-GCK | Mflv_2683 | - | 0.0 | 83.96% (455) | CBS domain-containing protein |
| M. tuberculosis H37Rv | Rv1842c | - | 4e-64 | 36.03% (433) | hypothetical protein Rv1842c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2411c | - | 6e-71 | 36.50% (411) | hypothetical protein MAB_2411c |
| M. marinum M | MMAR_2716 | - | 4e-66 | 36.14% (415) | hypothetical protein MMAR_2716 |
| M. avium 104 | MAV_2878 | - | 2e-63 | 34.23% (444) | CBS domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3637 | - | 5e-70 | 36.67% (439) | CBS domain-containing protein |
| M. thermoresistible (build 8) | TH_2608 | - | 1e-69 | 34.96% (452) | PUTATIVE protein of unknown function DUF21 |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3637|M.smegmatis_MC2_155 MGEVAMSDTNVWLSLLAILAVVLLTFGTAVFVAAEFSLTALERSTVEANA
TH_2608|M.thermoresistible__bu -----MSSVSVALS---ILAILLLTAGTAAFVAAEFSLTALERSTVEANA
MAB_2411c|M.abscessus_ATCC_199 -----MTVLLTGLS---LLAFVALTAGTALFVAAEFSLTALERSGIEARA
Mb1873c|M.bovis_AF2122/97 -----MNLTDTVAT---ILAILALTAGTGVFVAAEFSLTALDRSTVEANA
Rv1842c|M.tuberculosis_H37Rv -----MNLTDTVAT---ILAILALTAGTGVFVAAEFSLTALDRSTVEANA
MMAR_2716|M.marinum_M -----MMFTATTVS---IVAILVLTLGTAVFVGAEFSLTALDRSTVEANA
MAV_2878|M.avium_104 -----MNVTVTVVS---IVAIAVLIFGNAVFVAAEFSLTTLDRSTVEANA
Mvan_3860|M.vanbaalenii_PYR-1 -----MLTAVLGIFIG-FLVVLAITALTGYFVAQEFAYMAVDRSRLKARA
Mflv_2683|M.gilvum_PYR-GCK -----MLTAVLGILAG-FVVVLLITALTGYFVAQEFAYMAVDRSRLKARA
* ::.. : .. **. **: :::** ::*.*
MSMEG_3637|M.smegmatis_MC2_155 RAGDRRDHMVRHAHRTLSFQLSGAQVGISITTLATGYLAEPVIGKLIHPG
TH_2608|M.thermoresistible__bu RSGDRRDQMVRRAHRTLSFQLSGAQVGISITTLATGYLAEPVVARLLQPA
MAB_2411c|M.abscessus_ATCC_199 KTGDSRDRLVKRAHSTLSFQLSGAQLGITITTLVTGYLAEPVIARLLSQL
Mb1873c|M.bovis_AF2122/97 RGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYLTEPLVAELPHPG
Rv1842c|M.tuberculosis_H37Rv RGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYLTEPLVAELPHPG
MMAR_2716|M.marinum_M RGGDSRDRFIRRAQHRLSFHLSGAQLGISITTLATGYLTEPLVDALPHPA
MAV_2878|M.avium_104 RTGGRRDRWIRRAHHRLSFQLSGAQLGISATTLAAGYLTDPMVEDLPHPW
Mvan_3860|M.vanbaalenii_PYR-1 EAGDGASARALTVTRRTSFMLSGAQLGITVTGLLVGYVAEPLIGRGLEIL
Mflv_2683|M.gilvum_PYR-GCK EAGDAAAARALTVTRRTSFMLSGAQLGITVTGLLVGYVAEPLIGQGLETL
. * . ** *****:**: * * .**:::*::
MSMEG_3637|M.smegmatis_MC2_155 LDAIGIPANFAGGLSLFFAVVIATSLSMVFGELVPKNLAVARPVPTARAA
TH_2608|M.thermoresistible__bu IDAVGVPDRLAGGLSLFLAVSIATSLSMVFGELVPKNLAVARPVETARWS
MAB_2411c|M.abscessus_ATCC_199 FGYTGIAVSSA--ISLALALIIATSISMIFGELVPKNFALARPVWTSRAT
Mb1873c|M.bovis_AF2122/97 LVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSV
Rv1842c|M.tuberculosis_H37Rv LVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSV
MMAR_2716|M.marinum_M LTAIGISDQMSDAITVFLALVVVTSVSMVFGELVPKYLAVARPLPTARAV
MAV_2878|M.avium_104 LDAVGIPDRVGDAIMAFLALLIVTSVSMVFGELVPKYLAVARPMSTARAV
Mvan_3860|M.vanbaalenii_PYR-1 LGGAGIPTVIAVAVGGLFAIAVSTVVQMLFGELFPKNLAIARPEPLARWL
Mflv_2683|M.gilvum_PYR-GCK LGGTGIPTAVAIGIGGVVAIGFSTIVQMLFGELFPKNLAIARPEPLARWL
: *:. . : .*: . * :.*:****.** :*:*** :*
MSMEG_3637|M.smegmatis_MC2_155 APFQLLFSLIFTPVIRLTNGTANWILRRLGIEPAEELRSARTGQELAALV
TH_2608|M.thermoresistible__bu APLQVVFSALVTPLIRVTNGTANWILRRLGIEPAEELRSARSAQELVSLV
MAB_2411c|M.abscessus_ATCC_199 SGPMVLFSAVFAFAIRALNGTANWVLRRMGIEPAEELRSARSPQELGSLV
Mb1873c|M.bovis_AF2122/97 VAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELRSARTPQELVSLV
Rv1842c|M.tuberculosis_H37Rv VAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELRSARTPQELVSLV
MMAR_2716|M.marinum_M VLPQWLFSVLLTPAIRLTNGAANWIVRQLGIEPAEELRSARTPQELVSLV
MAV_2878|M.avium_104 VAAQLLFSALLTPAIRLTNGAANWIVRRLGVEPAEELRSARSPQELLSLV
Mvan_3860|M.vanbaalenii_PYR-1 AWSTTLYLKVFGWLIWLFDQSSNLLLRALRIEPVHDVEHSATVRDLEHIV
Mflv_2683|M.gilvum_PYR-GCK ARSTTVYLKLFGWLIWLFDQSSNLLLRALRIEPVHDVEHSATPRDLEHIV
:: :. * : ::* ::* : :**..::. : : ::* :*
MSMEG_3637|M.smegmatis_MC2_155 RNSARSGSLDPVTALLVDRSLQFGERTAEELMTPRPKIETLDADDTVVDL
TH_2608|M.thermoresistible__bu RNSAQSGSLDPVTARLVDRSLQFGDRTAEELMTPRSKIEALDADDTVADL
MAB_2411c|M.abscessus_ATCC_199 RTSARSGALDETTAVLVDRSLRFGSRTAEELMTPRTEIESLEATDTVADL
Mb1873c|M.bovis_AF2122/97 RSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIADL
Rv1842c|M.tuberculosis_H37Rv RSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIADL
MMAR_2716|M.marinum_M RSSARSGSLDDVTASLMRRSLQFGTLTAEELMTPRSKVVALQTDDTIADL
MAV_2878|M.avium_104 RSSARSGALDAATAALVRRSLQFGTLSAEELMTPRSKIVALQTDDTVADL
Mvan_3860|M.vanbaalenii_PYR-1 AASREAGEIPAELSALLDRILDFPTSTAEHAMIPRSRVDTVPAGESISSV
Mflv_2683|M.gilvum_PYR-GCK AASREAGEIPRELSALLDRILDFPTSTAEHAMIPRSRVDAIPADEPVAAV
* .:* : : *: * * * :**. * **..: :: : :.: :
MSMEG_3637|M.smegmatis_MC2_155 MDAAIRTGFSRFPIIKGDLDETIGVVHVKQVFAVPRDKRDRVRLASLALP
TH_2608|M.thermoresistible__bu IRVADETGFSRFPITRGDLDETVGMVHVKQVFEVPHDQRATTRLARLAVP
MAB_2411c|M.abscessus_ATCC_199 VTIAVETGFSRFPITEGDLDATIGIVHVKQVFEVPRDRRATTTLASLARP
Mb1873c|M.bovis_AF2122/97 VAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEP
Rv1842c|M.tuberculosis_H37Rv VAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEP
MMAR_2716|M.marinum_M VAAVAASGYSRFPVVQGDLDETFGIVHVKQVFQVPAAKRAHTLLSSIAKP
MAV_2878|M.avium_104 VTAAAESGFSRFPIVDGDLDETVGIVHVKQVFAIPRAARAHTLLTTVAQP
Mvan_3860|M.vanbaalenii_PYR-1 LQRMAT-GHTRYPVIGSSPDDIVGVVELHDLLGPVP---ATDTAGAHCRS
Mflv_2683|M.gilvum_PYR-GCK LSRMAS-GHTRYPVTGSHPDDVVGVIHLHDLLGDTR---TADLAGDRCRP
: *.:*:*: . * .*::.::::: . .
MSMEG_3637|M.smegmatis_MC2_155 VAKVPSTLDGDAVMTQIRANGLQTALVVDEYGGTAGMVTVEDLIEEIVGD
TH_2608|M.thermoresistible__bu VIKVPSTLDGDALMTQLRGNGLQTALVVDEYGGTAGMVTVEDMIEELVGD
MAB_2411c|M.abscessus_ATCC_199 VAVVPSTLDGDAVMEQVRANGMQTALVVDEYGGTAGLVTVEDMIEEIVGD
Mb1873c|M.bovis_AF2122/97 VAVVPSTLDGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGD
Rv1842c|M.tuberculosis_H37Rv VAVVPSTLDGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGD
MMAR_2716|M.marinum_M VPVVPSTLDGDALMAQIRANSLQTAMVVDEYGGTAGMVTVEDLVEEIVGD
MAV_2878|M.avium_104 VPVVPSTLDGDAVMAEIRANSLQTALVVDEYGGTAGMVTVEDLIEEIVGD
Mvan_3860|M.vanbaalenii_PYR-1 AVVVPETLPLPNVVRELQRADAEMAIVIDEYGGFAGIVTIEDLAEELVGE
Mflv_2683|M.gilvum_PYR-GCK AVIVPETLPLPNVVRELERGDDEMAVVIDEYGGFAGIVTIEDLAEELVGE
. **.** :: ::. : *:*:***** **:**:**: **:**:
MSMEG_3637|M.smegmatis_MC2_155 VRDEHD-DATPDVMPAGKGWQVSGLLRIDEVAAQTGFRAPEGEYETIGGL
TH_2608|M.thermoresistible__bu VRDEHD-DATPAVVRAPHGWQVSGLLRIDEVADQTGFRPPEGDYETIGGL
MAB_2411c|M.abscessus_ATCC_199 VRDEHD-DATPDVVSSGGGWVVSGLLRIDEVAAATGYRAPEGEYETIGGL
Mb1873c|M.bovis_AF2122/97 VRDEHD-DATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETIGGL
Rv1842c|M.tuberculosis_H37Rv VRDEHD-DATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETIGGL
MMAR_2716|M.marinum_M VRDEHD-DATPDVVAAGNGWRVSGLLRIDEVAIAIGYQAPEGPYETIGGL
MAV_2878|M.avium_104 VRDEHD-DATPDVVPAGTGWRVSGLLRIDEVAAATGFRAPEGPYETIGGL
Mvan_3860|M.vanbaalenii_PYR-1 IDDEHDTDAEADVVADGVGWLLAGDLPLDEAERTLDLVLPPGDYETVAGM
Mflv_2683|M.gilvum_PYR-GCK IDDEHDTDTEADVVADGDGWLLAGDLPLDEAERTLDLTLPPGDYETVAGM
: **** *: . *: ** ::* * :**. . * * ***:.*:
MSMEG_3637|M.smegmatis_MC2_155 VLQELGHIPETGEAVDLTAFDPDTDADEPTHWLATVVRMDGRRIDLLELT
TH_2608|M.thermoresistible__bu VLQELGHIPEAGEAVELTAFEPDGPMEDPVRWLATVVQMEGRRIDLLELV
MAB_2411c|M.abscessus_ATCC_199 VLQELGHIPTVGETVELTAVVPDHPLAELPRWRARVAGMDGRRIDQIELT
Mb1873c|M.bovis_AF2122/97 VLRELGHIPVAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDSLELI
Rv1842c|M.tuberculosis_H37Rv VLRELGHIPVAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDLLELI
MMAR_2716|M.marinum_M VLRQLGHIPVAGETVELPALDEDRVPDQSVRWRATVVQMDGRRIDLLELT
MAV_2878|M.avium_104 VLREIGHIPAAGETVKLPALDPDGLLDPVLRWQARVIRMDGRRIDVLELT
Mvan_3860|M.vanbaalenii_PYR-1 VIAHAVGLPAVGDEVVIALPADPADLLGDGVPPIRSLTAQVRSIERRVPA
Mflv_2683|M.gilvum_PYR-GCK VIAHAVGLPAVGDEVVIDLPGDPADLVNEGTPPIRRLVVEVRSIERRVPA
*: . :* .*: * : : * *:
MSMEG_3637|M.smegmatis_MC2_155 KLE---PAGEGEPNG----
TH_2608|M.thermoresistible__bu ELG---RGNGGPKAGVQR-
MAB_2411c|M.abscessus_ATCC_199 ELT---DADSRGNNDDG--
Mb1873c|M.bovis_AF2122/97 KMG----GHADPGSGRGR-
Rv1842c|M.tuberculosis_H37Rv KMG----GHADPGSGRGR-
MMAR_2716|M.marinum_M ELAGAEDGQDDSDPERGGR
MAV_2878|M.avium_104 EID----AHAEAPGGRR--
Mvan_3860|M.vanbaalenii_PYR-1 SVFVT--VSEGTGHE----
Mflv_2683|M.gilvum_PYR-GCK TVFVTERIDEEDGDE----
: