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LTAVLGILAGFVVVLLITALTGYFVAQEFAYMAVDRSRLKARAEAGDAAAARALTVTRRTSFMLSGAQLG ITVTGLLVGYVAEPLIGQGLETLLGGTGIPTAVAIGIGGVVAIGFSTIVQMLFGELFPKNLAIARPEPLA RWLARSTTVYLKLFGWLIWLFDQSSNLLLRALRIEPVHDVEHSATPRDLEHIVAASREAGEIPRELSALL DRILDFPTSTAEHAMIPRSRVDAIPADEPVAAVLSRMASGHTRYPVTGSHPDDVVGVIHLHDLLGDTRTA DLAGDRCRPAVIVPETLPLPNVVRELERGDDEMAVVIDEYGGFAGIVTIEDLAEELVGEIDDEHDTDTEA DVVADGDGWLLAGDLPLDEAERTLDLTLPPGDYETVAGMVIAHAVGLPAVGDEVVIDLPGDPADLVNEGT PPIRRLVVEVRSIERRVPATVFVTERIDEEDGDE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2683 | - | - | 100% (455) | CBS domain-containing protein |
| M. gilvum PYR-GCK | Mflv_3364 | - | 1e-72 | 35.94% (434) | hypothetical protein Mflv_3364 |
| M. gilvum PYR-GCK | Mflv_3365 | - | 3e-43 | 31.43% (350) | hypothetical protein Mflv_3365 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1873c | - | 9e-68 | 37.35% (415) | hypothetical protein Mb1873c |
| M. tuberculosis H37Rv | Rv1842c | - | 9e-68 | 37.35% (415) | hypothetical protein Rv1842c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2411c | - | 7e-72 | 36.73% (392) | hypothetical protein MAB_2411c |
| M. marinum M | MMAR_2716 | - | 4e-70 | 35.79% (447) | hypothetical protein MMAR_2716 |
| M. avium 104 | MAV_2878 | - | 5e-66 | 34.94% (435) | CBS domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3637 | - | 5e-70 | 35.94% (434) | CBS domain-containing protein |
| M. thermoresistible (build 8) | TH_2608 | - | 1e-73 | 36.94% (444) | PUTATIVE protein of unknown function DUF21 |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3860 | - | 0.0 | 83.96% (455) | hypothetical protein Mvan_3860 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3637|M.smegmatis_MC2_155 MGEVAMSDTNVWLSLLAILAVVLLTFGTAVFVAAEFSLTALERSTVEANA
TH_2608|M.thermoresistible__bu -----MSSVSVALS---ILAILLLTAGTAAFVAAEFSLTALERSTVEANA
MAB_2411c|M.abscessus_ATCC_199 -----MTVLLTGLS---LLAFVALTAGTALFVAAEFSLTALERSGIEARA
Mb1873c|M.bovis_AF2122/97 -----MNLTDTVAT---ILAILALTAGTGVFVAAEFSLTALDRSTVEANA
Rv1842c|M.tuberculosis_H37Rv -----MNLTDTVAT---ILAILALTAGTGVFVAAEFSLTALDRSTVEANA
MMAR_2716|M.marinum_M -----MMFTATTVS---IVAILVLTLGTAVFVGAEFSLTALDRSTVEANA
MAV_2878|M.avium_104 -----MNVTVTVVS---IVAIAVLIFGNAVFVAAEFSLTTLDRSTVEANA
Mflv_2683|M.gilvum_PYR-GCK -----MLTAVLGILAG-FVVVLLITALTGYFVAQEFAYMAVDRSRLKARA
Mvan_3860|M.vanbaalenii_PYR-1 -----MLTAVLGIFIG-FLVVLAITALTGYFVAQEFAYMAVDRSRLKARA
* ::.. : .. **. **: :::** ::*.*
MSMEG_3637|M.smegmatis_MC2_155 RAGDRRDHMVRHAHRTLSFQLSGAQVGISITTLATGYLAEPVIGKLIHPG
TH_2608|M.thermoresistible__bu RSGDRRDQMVRRAHRTLSFQLSGAQVGISITTLATGYLAEPVVARLLQPA
MAB_2411c|M.abscessus_ATCC_199 KTGDSRDRLVKRAHSTLSFQLSGAQLGITITTLVTGYLAEPVIARLLSQL
Mb1873c|M.bovis_AF2122/97 RGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYLTEPLVAELPHPG
Rv1842c|M.tuberculosis_H37Rv RGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYLTEPLVAELPHPG
MMAR_2716|M.marinum_M RGGDSRDRFIRRAQHRLSFHLSGAQLGISITTLATGYLTEPLVDALPHPA
MAV_2878|M.avium_104 RTGGRRDRWIRRAHHRLSFQLSGAQLGISATTLAAGYLTDPMVEDLPHPW
Mflv_2683|M.gilvum_PYR-GCK EAGDAAAARALTVTRRTSFMLSGAQLGITVTGLLVGYVAEPLIGQGLETL
Mvan_3860|M.vanbaalenii_PYR-1 EAGDGASARALTVTRRTSFMLSGAQLGITVTGLLVGYVAEPLIGRGLEIL
. * . ** *****:**: * * .**:::*::
MSMEG_3637|M.smegmatis_MC2_155 LDAIGIPANFAGGLSLFFAVVIATSLSMVFGELVPKNLAVARPVPTARAA
TH_2608|M.thermoresistible__bu IDAVGVPDRLAGGLSLFLAVSIATSLSMVFGELVPKNLAVARPVETARWS
MAB_2411c|M.abscessus_ATCC_199 FGYTGIAVSSA--ISLALALIIATSISMIFGELVPKNFALARPVWTSRAT
Mb1873c|M.bovis_AF2122/97 LVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSV
Rv1842c|M.tuberculosis_H37Rv LVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSV
MMAR_2716|M.marinum_M LTAIGISDQMSDAITVFLALVVVTSVSMVFGELVPKYLAVARPLPTARAV
MAV_2878|M.avium_104 LDAVGIPDRVGDAIMAFLALLIVTSVSMVFGELVPKYLAVARPMSTARAV
Mflv_2683|M.gilvum_PYR-GCK LGGTGIPTAVAIGIGGVVAIGFSTIVQMLFGELFPKNLAIARPEPLARWL
Mvan_3860|M.vanbaalenii_PYR-1 LGGAGIPTVIAVAVGGLFAIAVSTVVQMLFGELFPKNLAIARPEPLARWL
: *:. . : .*: . * :.*:****.** :*:*** :*
MSMEG_3637|M.smegmatis_MC2_155 APFQLLFSLIFTPVIRLTNGTANWILRRLGIEPAEELRSARTGQELAALV
TH_2608|M.thermoresistible__bu APLQVVFSALVTPLIRVTNGTANWILRRLGIEPAEELRSARSAQELVSLV
MAB_2411c|M.abscessus_ATCC_199 SGPMVLFSAVFAFAIRALNGTANWVLRRMGIEPAEELRSARSPQELGSLV
Mb1873c|M.bovis_AF2122/97 VAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELRSARTPQELVSLV
Rv1842c|M.tuberculosis_H37Rv VAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELRSARTPQELVSLV
MMAR_2716|M.marinum_M VLPQWLFSVLLTPAIRLTNGAANWIVRQLGIEPAEELRSARTPQELVSLV
MAV_2878|M.avium_104 VAAQLLFSALLTPAIRLTNGAANWIVRRLGVEPAEELRSARSPQELLSLV
Mflv_2683|M.gilvum_PYR-GCK ARSTTVYLKLFGWLIWLFDQSSNLLLRALRIEPVHDVEHSATPRDLEHIV
Mvan_3860|M.vanbaalenii_PYR-1 AWSTTLYLKVFGWLIWLFDQSSNLLLRALRIEPVHDVEHSATVRDLEHIV
:: :. * : ::* ::* : :**..::. : : ::* :*
MSMEG_3637|M.smegmatis_MC2_155 RNSARSGSLDPVTALLVDRSLQFGERTAEELMTPRPKIETLDADDTVVDL
TH_2608|M.thermoresistible__bu RNSAQSGSLDPVTARLVDRSLQFGDRTAEELMTPRSKIEALDADDTVADL
MAB_2411c|M.abscessus_ATCC_199 RTSARSGALDETTAVLVDRSLRFGSRTAEELMTPRTEIESLEATDTVADL
Mb1873c|M.bovis_AF2122/97 RSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIADL
Rv1842c|M.tuberculosis_H37Rv RSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIADL
MMAR_2716|M.marinum_M RSSARSGSLDDVTASLMRRSLQFGTLTAEELMTPRSKVVALQTDDTIADL
MAV_2878|M.avium_104 RSSARSGALDAATAALVRRSLQFGTLSAEELMTPRSKIVALQTDDTVADL
Mflv_2683|M.gilvum_PYR-GCK AASREAGEIPRELSALLDRILDFPTSTAEHAMIPRSRVDAIPADEPVAAV
Mvan_3860|M.vanbaalenii_PYR-1 AASREAGEIPAELSALLDRILDFPTSTAEHAMIPRSRVDTVPAGESISSV
* .:* : : *: * * * :**. * **..: :: : :.: :
MSMEG_3637|M.smegmatis_MC2_155 MDAAIRTGFSRFPIIKGDLDETIGVVHVKQVFAVPRDKRDRVRLASLALP
TH_2608|M.thermoresistible__bu IRVADETGFSRFPITRGDLDETVGMVHVKQVFEVPHDQRATTRLARLAVP
MAB_2411c|M.abscessus_ATCC_199 VTIAVETGFSRFPITEGDLDATIGIVHVKQVFEVPRDRRATTTLASLARP
Mb1873c|M.bovis_AF2122/97 VAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEP
Rv1842c|M.tuberculosis_H37Rv VAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEP
MMAR_2716|M.marinum_M VAAVAASGYSRFPVVQGDLDETFGIVHVKQVFQVPAAKRAHTLLSSIAKP
MAV_2878|M.avium_104 VTAAAESGFSRFPIVDGDLDETVGIVHVKQVFAIPRAARAHTLLTTVAQP
Mflv_2683|M.gilvum_PYR-GCK LSRMAS-GHTRYPVTGSHPDDVVGVIHLHDLLGDTR---TADLAGDRCRP
Mvan_3860|M.vanbaalenii_PYR-1 LQRMAT-GHTRYPVIGSSPDDIVGVVELHDLLGPVP---ATDTAGAHCRS
: *.:*:*: . * .*::.::::: . .
MSMEG_3637|M.smegmatis_MC2_155 VAKVPSTLDGDAVMTQIRANGLQTALVVDEYGGTAGMVTVEDLIEEIVGD
TH_2608|M.thermoresistible__bu VIKVPSTLDGDALMTQLRGNGLQTALVVDEYGGTAGMVTVEDMIEELVGD
MAB_2411c|M.abscessus_ATCC_199 VAVVPSTLDGDAVMEQVRANGMQTALVVDEYGGTAGLVTVEDMIEEIVGD
Mb1873c|M.bovis_AF2122/97 VAVVPSTLDGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGD
Rv1842c|M.tuberculosis_H37Rv VAVVPSTLDGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGD
MMAR_2716|M.marinum_M VPVVPSTLDGDALMAQIRANSLQTAMVVDEYGGTAGMVTVEDLVEEIVGD
MAV_2878|M.avium_104 VPVVPSTLDGDAVMAEIRANSLQTALVVDEYGGTAGMVTVEDLIEEIVGD
Mflv_2683|M.gilvum_PYR-GCK AVIVPETLPLPNVVRELERGDDEMAVVIDEYGGFAGIVTIEDLAEELVGE
Mvan_3860|M.vanbaalenii_PYR-1 AVVVPETLPLPNVVRELQRADAEMAIVIDEYGGFAGIVTIEDLAEELVGE
. **.** :: ::. : *:*:***** **:**:**: **:**:
MSMEG_3637|M.smegmatis_MC2_155 VRDEHD-DATPDVMPAGKGWQVSGLLRIDEVAAQTGFRAPEGEYETIGGL
TH_2608|M.thermoresistible__bu VRDEHD-DATPAVVRAPHGWQVSGLLRIDEVADQTGFRPPEGDYETIGGL
MAB_2411c|M.abscessus_ATCC_199 VRDEHD-DATPDVVSSGGGWVVSGLLRIDEVAAATGYRAPEGEYETIGGL
Mb1873c|M.bovis_AF2122/97 VRDEHD-DATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETIGGL
Rv1842c|M.tuberculosis_H37Rv VRDEHD-DATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETIGGL
MMAR_2716|M.marinum_M VRDEHD-DATPDVVAAGNGWRVSGLLRIDEVAIAIGYQAPEGPYETIGGL
MAV_2878|M.avium_104 VRDEHD-DATPDVVPAGTGWRVSGLLRIDEVAAATGFRAPEGPYETIGGL
Mflv_2683|M.gilvum_PYR-GCK IDDEHDTDTEADVVADGDGWLLAGDLPLDEAERTLDLTLPPGDYETVAGM
Mvan_3860|M.vanbaalenii_PYR-1 IDDEHDTDAEADVVADGVGWLLAGDLPLDEAERTLDLVLPPGDYETVAGM
: **** *: . *: ** ::* * :**. . * * ***:.*:
MSMEG_3637|M.smegmatis_MC2_155 VLQELGHIPETGEAVDLTAFDPDTDADEPTHWLATVVRMDGRRIDLLELT
TH_2608|M.thermoresistible__bu VLQELGHIPEAGEAVELTAFEPDGPMEDPVRWLATVVQMEGRRIDLLELV
MAB_2411c|M.abscessus_ATCC_199 VLQELGHIPTVGETVELTAVVPDHPLAELPRWRARVAGMDGRRIDQIELT
Mb1873c|M.bovis_AF2122/97 VLRELGHIPVAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDSLELI
Rv1842c|M.tuberculosis_H37Rv VLRELGHIPVAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDLLELI
MMAR_2716|M.marinum_M VLRQLGHIPVAGETVELPALDEDRVPDQSVRWRATVVQMDGRRIDLLELT
MAV_2878|M.avium_104 VLREIGHIPAAGETVKLPALDPDGLLDPVLRWQARVIRMDGRRIDVLELT
Mflv_2683|M.gilvum_PYR-GCK VIAHAVGLPAVGDEVVIDLPGDPADLVNEGTPPIRRLVVEVRSIERRVPA
Mvan_3860|M.vanbaalenii_PYR-1 VIAHAVGLPAVGDEVVIALPADPADLLGDGVPPIRSLTAQVRSIERRVPA
*: . :* .*: * : : * *:
MSMEG_3637|M.smegmatis_MC2_155 KLE---PAGEGEPNG----
TH_2608|M.thermoresistible__bu ELG---RGNGGPKAGVQR-
MAB_2411c|M.abscessus_ATCC_199 ELT---DADSRGNNDDG--
Mb1873c|M.bovis_AF2122/97 KMG----GHADPGSGRGR-
Rv1842c|M.tuberculosis_H37Rv KMG----GHADPGSGRGR-
MMAR_2716|M.marinum_M ELAGAEDGQDDSDPERGGR
MAV_2878|M.avium_104 EID----AHAEAPGGRR--
Mflv_2683|M.gilvum_PYR-GCK TVFVTERIDEEDGDE----
Mvan_3860|M.vanbaalenii_PYR-1 SVFVT--VSEGTGHE----
: