For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSSNLSLLALLAFMLLTAGTAVFVAAEFSLTALERSTVEANVRSGDRRDVMVQRAHRTLSTQLSGAQVGI SITTLATGFLAEPVVARLIHPGLTAIGIPDRFVGGLALTLAILIATSISMVFGELVPKNLAVARPVPTAR WSAPLQLMFSFLFTPLIRLTNGTANWILRRLGIEPAEELRSARSPQELVSLVRSSAERGSLDPVTALLVD RSLQFGDRSAEELMTPRSKIDTLEADDTVADLSDAATRTGHSRFPVIRGDLDETVGMVHVKQVFAVPADA RATTRLATLVQPVTKVPSTLDGDAVMSEVRANGLQTALVVDEYGGTAGMVTVEDLIEEIVGDVRDEHDVE PPDVVQAGRGWQVSGLLRIDEVAQGTEFRAPEGDYETIGGLVLEKLGHIPEEGESVELIAFDPDGPIQDP VHWLATVVKMDGRRIDQLRLTELGRKGDSRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3094 | - | - | 100% (451) | hypothetical protein Mvan_3094 |
| M. vanbaalenii PYR-1 | Mvan_3860 | - | 4e-71 | 36.64% (434) | hypothetical protein Mvan_3860 |
| M. vanbaalenii PYR-1 | Mvan_3095 | - | 2e-48 | 35.28% (343) | hypothetical protein Mvan_3095 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1873c | - | 1e-168 | 69.07% (443) | hypothetical protein Mb1873c |
| M. gilvum PYR-GCK | Mflv_3364 | - | 0.0 | 88.64% (449) | hypothetical protein Mflv_3364 |
| M. tuberculosis H37Rv | Rv1842c | - | 1e-168 | 69.07% (443) | hypothetical protein Rv1842c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2411c | - | 1e-165 | 67.71% (449) | hypothetical protein MAB_2411c |
| M. marinum M | MMAR_2716 | - | 1e-164 | 66.67% (450) | hypothetical protein MMAR_2716 |
| M. avium 104 | MAV_2878 | - | 1e-168 | 68.07% (451) | CBS domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3637 | - | 0.0 | 79.05% (444) | CBS domain-containing protein |
| M. thermoresistible (build 8) | TH_2608 | - | 0.0 | 79.78% (445) | PUTATIVE protein of unknown function DUF21 |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3094|M.vanbaalenii_PYR-1 -----MSSN---LSLLALLAFMLLTAGTAVFVAAEFSLTALERSTVEANV
Mflv_3364|M.gilvum_PYR-GCK -----MNTA---MSLLALLAFMLLTAGTAVFVAAEFSLTALERSTVEANV
TH_2608|M.thermoresistible__bu -----MSSV---SVALSILAILLLTAGTAAFVAAEFSLTALERSTVEANA
MSMEG_3637|M.smegmatis_MC2_155 MGEVAMSDTNVWLSLLAILAVVLLTFGTAVFVAAEFSLTALERSTVEANA
MAB_2411c|M.abscessus_ATCC_199 -----MTVL---LTGLSLLAFVALTAGTALFVAAEFSLTALERSGIEARA
Mb1873c|M.bovis_AF2122/97 -----MNLT---DTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANA
Rv1842c|M.tuberculosis_H37Rv -----MNLT---DTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANA
MMAR_2716|M.marinum_M -----MMFT---ATTVSIVAILVLTLGTAVFVGAEFSLTALDRSTVEANA
MAV_2878|M.avium_104 -----MNVT---VTVVSIVAIAVLIFGNAVFVAAEFSLTTLDRSTVEANA
* :::*. * *.. **.******:*:** :**..
Mvan_3094|M.vanbaalenii_PYR-1 RSGDRRDVMVQRAHRTLSTQLSGAQVGISITTLATGFLAEPVVARLIHPG
Mflv_3364|M.gilvum_PYR-GCK RSGDRRDAMVQRAHRSLSTQLSGAQVGISITTLATGFLAEPVVARLIHPG
TH_2608|M.thermoresistible__bu RSGDRRDQMVRRAHRTLSFQLSGAQVGISITTLATGYLAEPVVARLLQPA
MSMEG_3637|M.smegmatis_MC2_155 RAGDRRDHMVRHAHRTLSFQLSGAQVGISITTLATGYLAEPVIGKLIHPG
MAB_2411c|M.abscessus_ATCC_199 KTGDSRDRLVKRAHSTLSFQLSGAQLGITITTLVTGYLAEPVIARLLSQL
Mb1873c|M.bovis_AF2122/97 RGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYLTEPLVAELPHPG
Rv1842c|M.tuberculosis_H37Rv RGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYLTEPLVAELPHPG
MMAR_2716|M.marinum_M RGGDSRDRFIRRAQHRLSFHLSGAQLGISITTLATGYLTEPLVDALPHPA
MAV_2878|M.avium_104 RTGGRRDRWIRRAHHRLSFQLSGAQLGISATTLAAGYLTDPMVEDLPHPW
: * ** :::*: ** :*****:**: ***.:*:*::*:: *
Mvan_3094|M.vanbaalenii_PYR-1 LTAIGIPDRFVGGLALTLAILIATSISMVFGELVPKNLAVARPVPTARWS
Mflv_3364|M.gilvum_PYR-GCK LTALNVPGQFVSGLSLFLAILIATSISMIFGELVPKNLAVAKPVPTARWS
TH_2608|M.thermoresistible__bu IDAVGVPDRLAGGLSLFLAVSIATSLSMVFGELVPKNLAVARPVETARWS
MSMEG_3637|M.smegmatis_MC2_155 LDAIGIPANFAGGLSLFFAVVIATSLSMVFGELVPKNLAVARPVPTARAA
MAB_2411c|M.abscessus_ATCC_199 FGYTGIA--VSSAISLALALIIATSISMIFGELVPKNFALARPVWTSRAT
Mb1873c|M.bovis_AF2122/97 LVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSV
Rv1842c|M.tuberculosis_H37Rv LVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSV
MMAR_2716|M.marinum_M LTAIGISDQMSDAITVFLALVVVTSVSMVFGELVPKYLAVARPLPTARAV
MAV_2878|M.avium_104 LDAVGIPDRVGDAIMAFLALLIVTSVSMVFGELVPKYLAVARPMSTARAV
: .:. . ..: :*: :.**:**:******* :*:*:*: *:*
Mvan_3094|M.vanbaalenii_PYR-1 APLQLMFSFLFTPLIRLTNGTANWILRRLGIEPAEELRSARSPQELVSLV
Mflv_3364|M.gilvum_PYR-GCK APLQLMFSFLALPLIRLTNGTANWILRRLGIEPAEELRSARSPQELVSLV
TH_2608|M.thermoresistible__bu APLQVVFSALVTPLIRVTNGTANWILRRLGIEPAEELRSARSAQELVSLV
MSMEG_3637|M.smegmatis_MC2_155 APFQLLFSLIFTPVIRLTNGTANWILRRLGIEPAEELRSARTGQELAALV
MAB_2411c|M.abscessus_ATCC_199 SGPMVLFSAVFAFAIRALNGTANWVLRRMGIEPAEELRSARSPQELGSLV
Mb1873c|M.bovis_AF2122/97 VAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELRSARTPQELVSLV
Rv1842c|M.tuberculosis_H37Rv VAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELRSARTPQELVSLV
MMAR_2716|M.marinum_M VLPQWLFSVLLTPAIRLTNGAANWIVRQLGIEPAEELRSARTPQELVSLV
MAV_2878|M.avium_104 VAAQLLFSALLTPAIRLTNGAANWIVRRLGVEPAEELRSARSPQELLSLV
:** : ** **:***::*::*:**********: *** :**
Mvan_3094|M.vanbaalenii_PYR-1 RSSAERGSLDPVTALLVDRSLQFGDRSAEELMTPRSKIDTLEADDTVADL
Mflv_3364|M.gilvum_PYR-GCK RSSAERGSLDPVTAQLVDRSLQFGDRTAEELMTPRSKIDTLDADDTVLDL
TH_2608|M.thermoresistible__bu RNSAQSGSLDPVTARLVDRSLQFGDRTAEELMTPRSKIEALDADDTVADL
MSMEG_3637|M.smegmatis_MC2_155 RNSARSGSLDPVTALLVDRSLQFGERTAEELMTPRPKIETLDADDTVVDL
MAB_2411c|M.abscessus_ATCC_199 RTSARSGALDETTAVLVDRSLRFGSRTAEELMTPRTEIESLEATDTVADL
Mb1873c|M.bovis_AF2122/97 RSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIADL
Rv1842c|M.tuberculosis_H37Rv RSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIADL
MMAR_2716|M.marinum_M RSSARSGSLDDVTASLMRRSLQFGTLTAEELMTPRSKVVALQTDDTIADL
MAV_2878|M.avium_104 RSSARSGALDAATAALVRRSLQFGTLSAEELMTPRSKIVALQTDDTVADL
*.**. *:** .** *: ***:** :********.:: :*:: **: **
Mvan_3094|M.vanbaalenii_PYR-1 SDAATRTGHSRFPVIRGDLDETVGMVHVKQVFAVPADARATTRLATLVQP
Mflv_3364|M.gilvum_PYR-GCK SEAAVSTGHSRFPVIHGDLDETIGMVHVKQVFEVPAVSRSTTRLADLVQP
TH_2608|M.thermoresistible__bu IRVADETGFSRFPITRGDLDETVGMVHVKQVFEVPHDQRATTRLARLAVP
MSMEG_3637|M.smegmatis_MC2_155 MDAAIRTGFSRFPIIKGDLDETIGVVHVKQVFAVPRDKRDRVRLASLALP
MAB_2411c|M.abscessus_ATCC_199 VTIAVETGFSRFPITEGDLDATIGIVHVKQVFEVPRDRRATTTLASLARP
Mb1873c|M.bovis_AF2122/97 VAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEP
Rv1842c|M.tuberculosis_H37Rv VAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEP
MMAR_2716|M.marinum_M VAAVAASGYSRFPVVQGDLDETFGIVHVKQVFQVPAAKRAHTLLSSIAKP
MAV_2878|M.avium_104 VTAAAESGFSRFPIVDGDLDETVGIVHVKQVFAIPRAARAHTLLTTVAQP
. :*.****: **** *.*:******* :* * . *: :. *
Mvan_3094|M.vanbaalenii_PYR-1 VTKVPSTLDGDAVMSEVRANGLQTALVVDEYGGTAGMVTVEDLIEEIVGD
Mflv_3364|M.gilvum_PYR-GCK LTKVPSTLDGDAVMAEVRANGLQTALVVDEYGGTAGMVTVEDLIEEIVGD
TH_2608|M.thermoresistible__bu VIKVPSTLDGDALMTQLRGNGLQTALVVDEYGGTAGMVTVEDMIEELVGD
MSMEG_3637|M.smegmatis_MC2_155 VAKVPSTLDGDAVMTQIRANGLQTALVVDEYGGTAGMVTVEDLIEEIVGD
MAB_2411c|M.abscessus_ATCC_199 VAVVPSTLDGDAVMEQVRANGMQTALVVDEYGGTAGLVTVEDMIEEIVGD
Mb1873c|M.bovis_AF2122/97 VAVVPSTLDGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGD
Rv1842c|M.tuberculosis_H37Rv VAVVPSTLDGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGD
MMAR_2716|M.marinum_M VPVVPSTLDGDALMAQIRANSLQTAMVVDEYGGTAGMVTVEDLVEEIVGD
MAV_2878|M.avium_104 VPVVPSTLDGDAVMAEIRANSLQTALVVDEYGGTAGMVTVEDLIEEIVGD
: *********:* ::*...:***:**********:**:**::**:***
Mvan_3094|M.vanbaalenii_PYR-1 VRDEHDVEPPDVVQAGRGWQVSGLLRIDEVAQGTEFRAPEGDYETIGGLV
Mflv_3364|M.gilvum_PYR-GCK VRDEHDDEPPDVVAAGQGWQVSGLLRIDEVAEGTAFRAPEGDYETIGGLI
TH_2608|M.thermoresistible__bu VRDEHDDATPAVVRAPHGWQVSGLLRIDEVADQTGFRPPEGDYETIGGLV
MSMEG_3637|M.smegmatis_MC2_155 VRDEHDDATPDVMPAGKGWQVSGLLRIDEVAAQTGFRAPEGEYETIGGLV
MAB_2411c|M.abscessus_ATCC_199 VRDEHDDATPDVVSSGGGWVVSGLLRIDEVAAATGYRAPEGEYETIGGLV
Mb1873c|M.bovis_AF2122/97 VRDEHDDATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETIGGLV
Rv1842c|M.tuberculosis_H37Rv VRDEHDDATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETIGGLV
MMAR_2716|M.marinum_M VRDEHDDATPDVVAAGNGWRVSGLLRIDEVAIAIGYQAPEGPYETIGGLV
MAV_2878|M.avium_104 VRDEHDDATPDVVPAGTGWRVSGLLRIDEVAAATGFRAPEGPYETIGGLV
****** .* *: : ** *********** ::.*:* *******:
Mvan_3094|M.vanbaalenii_PYR-1 LEKLGHIPEEGESVELIAFDPDGPIQDPVHWLATVVKMDGRRIDQLRLTE
Mflv_3364|M.gilvum_PYR-GCK LEKLGHIPDEGETVELTAFDPDGAIEDPVRWLATVIKMDGRRIDQLRLTR
TH_2608|M.thermoresistible__bu LQELGHIPEAGEAVELTAFEPDGPMEDPVRWLATVVQMEGRRIDLLELVE
MSMEG_3637|M.smegmatis_MC2_155 LQELGHIPETGEAVDLTAFDPDTDADEPTHWLATVVRMDGRRIDLLELTK
MAB_2411c|M.abscessus_ATCC_199 LQELGHIPTVGETVELTAVVPDHPLAELPRWRARVAGMDGRRIDQIELTE
Mb1873c|M.bovis_AF2122/97 LRELGHIPVAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDSLELIK
Rv1842c|M.tuberculosis_H37Rv LRELGHIPVAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDLLELIK
MMAR_2716|M.marinum_M LRQLGHIPVAGETVELPALDEDRVPDQSVRWRATVVQMDGRRIDLLELTE
MAV_2878|M.avium_104 LREIGHIPAAGETVKLPALDPDGLLDPVLRWQARVIRMDGRRIDVLELTE
*.::**** **:*.* *. * :* * * *:***** :.* .
Mvan_3094|M.vanbaalenii_PYR-1 LG---RKGDS------RG
Mflv_3364|M.gilvum_PYR-GCK LG---RLSDAPEGEDHRG
TH_2608|M.thermoresistible__bu LG---RGNGGPKAGVQR-
MSMEG_3637|M.smegmatis_MC2_155 LE---PAGEGEPNG----
MAB_2411c|M.abscessus_ATCC_199 LT---DADSRGNNDDG--
Mb1873c|M.bovis_AF2122/97 MG----GHADPGSGRGR-
Rv1842c|M.tuberculosis_H37Rv MG----GHADPGSGRGR-
MMAR_2716|M.marinum_M LAGAEDGQDDSDPERGGR
MAV_2878|M.avium_104 ID----AHAEAPGGRR--
: