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TVLLTGLSLLAFVALTAGTALFVAAEFSLTALERSGIEARAKTGDSRDRLVKRAHSTLSFQLSGAQLGIT ITTLVTGYLAEPVIARLLSQLFGYTGIAVSSAISLALALIIATSISMIFGELVPKNFALARPVWTSRATS GPMVLFSAVFAFAIRALNGTANWVLRRMGIEPAEELRSARSPQELGSLVRTSARSGALDETTAVLVDRSL RFGSRTAEELMTPRTEIESLEATDTVADLVTIAVETGFSRFPITEGDLDATIGIVHVKQVFEVPRDRRAT TTLASLARPVAVVPSTLDGDAVMEQVRANGMQTALVVDEYGGTAGLVTVEDMIEEIVGDVRDEHDDATPD VVSSGGGWVVSGLLRIDEVAAATGYRAPEGEYETIGGLVLQELGHIPTVGETVELTAVVPDHPLAELPRW RARVAGMDGRRIDQIELTELTDADSRGNNDDG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2411c | - | - | 100% (453) | hypothetical protein MAB_2411c |
| M. abscessus ATCC 19977 | MAB_2410c | - | 5e-41 | 31.49% (343) | hypothetical protein MAB_2410c |
| M. abscessus ATCC 19977 | MAB_1670 | - | 2e-30 | 25.19% (405) | hypothetical protein MAB_1670 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1873c | - | 1e-160 | 66.67% (438) | hypothetical protein Mb1873c |
| M. gilvum PYR-GCK | Mflv_3364 | - | 1e-162 | 68.26% (438) | hypothetical protein Mflv_3364 |
| M. tuberculosis H37Rv | Rv1842c | - | 1e-160 | 66.67% (438) | hypothetical protein Rv1842c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2716 | - | 1e-160 | 63.70% (449) | hypothetical protein MMAR_2716 |
| M. avium 104 | MAV_2878 | - | 1e-161 | 66.37% (443) | CBS domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3637 | - | 1e-169 | 70.05% (444) | CBS domain-containing protein |
| M. thermoresistible (build 8) | TH_2608 | - | 1e-170 | 70.27% (444) | PUTATIVE protein of unknown function DUF21 |
| M. ulcerans Agy99 | MUL_3269 | - | 8e-05 | 28.57% (105) | hypothetical protein MUL_3269 |
| M. vanbaalenii PYR-1 | Mvan_3094 | - | 1e-164 | 67.71% (449) | hypothetical protein Mvan_3094 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1873c|M.bovis_AF2122/97 -----MNLT---DTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANA
Rv1842c|M.tuberculosis_H37Rv -----MNLT---DTVATILAILALTAGTGVFVAAEFSLTALDRSTVEANA
MMAR_2716|M.marinum_M -----MMFT---ATTVSIVAILVLTLGTAVFVGAEFSLTALDRSTVEANA
MAV_2878|M.avium_104 -----MNVT---VTVVSIVAIAVLIFGNAVFVAAEFSLTTLDRSTVEANA
Mflv_3364|M.gilvum_PYR-GCK -----MNTA---MSLLALLAFMLLTAGTAVFVAAEFSLTALERSTVEANV
Mvan_3094|M.vanbaalenii_PYR-1 -----MSSN---LSLLALLAFMLLTAGTAVFVAAEFSLTALERSTVEANV
TH_2608|M.thermoresistible__bu -----MSSV---SVALSILAILLLTAGTAAFVAAEFSLTALERSTVEANA
MSMEG_3637|M.smegmatis_MC2_155 MGEVAMSDTNVWLSLLAILAVVLLTFGTAVFVAAEFSLTALERSTVEANA
MAB_2411c|M.abscessus_ATCC_199 -----MTVL---LTGLSLLAFVALTAGTALFVAAEFSLTALERSGIEARA
MUL_3269|M.ulcerans_Agy99 -----MSDE----IPLGRIAGFAVKVHWSVLVILWLFTWSLATTLPETAK
* :* : . :* : :* : *:
Mb1873c|M.bovis_AF2122/97 RGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYLTEPLVAELPHPG
Rv1842c|M.tuberculosis_H37Rv RGGTSRDRFIQRAHHRLSFQLSGAQLGISITTLATGYLTEPLVAELPHPG
MMAR_2716|M.marinum_M RGGDSRDRFIRRAQHRLSFHLSGAQLGISITTLATGYLTEPLVDALPHPA
MAV_2878|M.avium_104 RTGGRRDRWIRRAHHRLSFQLSGAQLGISATTLAAGYLTDPMVEDLPHPW
Mflv_3364|M.gilvum_PYR-GCK RSGDRRDAMVQRAHRSLSTQLSGAQVGISITTLATGFLAEPVVARLIHPG
Mvan_3094|M.vanbaalenii_PYR-1 RSGDRRDVMVQRAHRTLSTQLSGAQVGISITTLATGFLAEPVVARLIHPG
TH_2608|M.thermoresistible__bu RSGDRRDQMVRRAHRTLSFQLSGAQVGISITTLATGYLAEPVVARLLQPA
MSMEG_3637|M.smegmatis_MC2_155 RAGDRRDHMVRHAHRTLSFQLSGAQVGISITTLATGYLAEPVIGKLIHPG
MAB_2411c|M.abscessus_ATCC_199 KTGDSRDRLVKRAHSTLSFQLSGAQLGITITTLVTGYLAEPVIARLLSQL
MUL_3269|M.ulcerans_Agy99 GYG-----------AVVYWIAGGCGALVLLASLLAHELAHAIAAR--RAG
* : .*. : ::* : *:..:
Mb1873c|M.bovis_AF2122/97 LVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSV
Rv1842c|M.tuberculosis_H37Rv LVAVGMSDRVADGLITFFALVIVTSLSMVFGELVPKYLAVARPLRTARSV
MMAR_2716|M.marinum_M LTAIGISDQMSDAITVFLALVVVTSVSMVFGELVPKYLAVARPLPTARAV
MAV_2878|M.avium_104 LDAVGIPDRVGDAIMAFLALLIVTSVSMVFGELVPKYLAVARPMSTARAV
Mflv_3364|M.gilvum_PYR-GCK LTALNVPGQFVSGLSLFLAILIATSISMIFGELVPKNLAVAKPVPTARWS
Mvan_3094|M.vanbaalenii_PYR-1 LTAIGIPDRFVGGLALTLAILIATSISMVFGELVPKNLAVARPVPTARWS
TH_2608|M.thermoresistible__bu IDAVGVPDRLAGGLSLFLAVSIATSLSMVFGELVPKNLAVARPVETARWS
MSMEG_3637|M.smegmatis_MC2_155 LDAIGIPANFAGGLSLFFAVVIATSLSMVFGELVPKNLAVARPVPTARAA
MAB_2411c|M.abscessus_ATCC_199 FGYTGIA--VSSAISLALALIIATSISMIFGELVPKNFALARPVWTSRAT
MUL_3269|M.ulcerans_Agy99 VPVGNVTLWLFGGVTTLGGEAKTPKAAFRIAFAGPATSLALSAMFTAVAV
. .:. . ..: . ... :: :. * .: *:
Mb1873c|M.bovis_AF2122/97 VAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELRSARTPQELVSLV
Rv1842c|M.tuberculosis_H37Rv VAGQVLFSLLLTPAIRLTNGAANWIVRRLGIEPAEELRSARTPQELVSLV
MMAR_2716|M.marinum_M VLPQWLFSVLLTPAIRLTNGAANWIVRQLGIEPAEELRSARTPQELVSLV
MAV_2878|M.avium_104 VAAQLLFSALLTPAIRLTNGAANWIVRRLGVEPAEELRSARSPQELLSLV
Mflv_3364|M.gilvum_PYR-GCK APLQLMFSFLALPLIRLTNGTANWILRRLGIEPAEELRSARSPQELVSLV
Mvan_3094|M.vanbaalenii_PYR-1 APLQLMFSFLFTPLIRLTNGTANWILRRLGIEPAEELRSARSPQELVSLV
TH_2608|M.thermoresistible__bu APLQVVFSALVTPLIRVTNGTANWILRRLGIEPAEELRSARSAQELVSLV
MSMEG_3637|M.smegmatis_MC2_155 APFQLLFSLIFTPVIRLTNGTANWILRRLGIEPAEELRSARTGQELAALV
MAB_2411c|M.abscessus_ATCC_199 SGPMVLFSAVFAFAIRALNGTANWVLRRMGIEPAEELRSARSPQELGSLV
MUL_3269|M.ulcerans_Agy99 ALAMVRTPDLVVSVVWWLA-AVNLMLGLFNLLPGAPLDGGR-------LV
. : : :.* :: :.: *. * ..* **
Mb1873c|M.bovis_AF2122/97 RSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIADL
Rv1842c|M.tuberculosis_H37Rv RSSARSGALDDATAWLMRRSLQFGALTAEELMTPRSKIVALQTDDTIADL
MMAR_2716|M.marinum_M RSSARSGSLDDVTASLMRRSLQFGTLTAEELMTPRSKVVALQTDDTIADL
MAV_2878|M.avium_104 RSSARSGALDAATAALVRRSLQFGTLSAEELMTPRSKIVALQTDDTVADL
Mflv_3364|M.gilvum_PYR-GCK RSSAERGSLDPVTAQLVDRSLQFGDRTAEELMTPRSKIDTLDADDTVLDL
Mvan_3094|M.vanbaalenii_PYR-1 RSSAERGSLDPVTALLVDRSLQFGDRSAEELMTPRSKIDTLEADDTVADL
TH_2608|M.thermoresistible__bu RNSAQSGSLDPVTARLVDRSLQFGDRTAEELMTPRSKIEALDADDTVADL
MSMEG_3637|M.smegmatis_MC2_155 RNSARSGSLDPVTALLVDRSLQFGERTAEELMTPRPKIETLDADDTVVDL
MAB_2411c|M.abscessus_ATCC_199 RTSARSGALDETTAVLVDRSLRFGSRTAEELMTPRTEIESLEATDTVADL
MUL_3269|M.ulcerans_Agy99 RAYLWRRHGDIVRAGIG--AARAGRVVALVLIILG------LAEFVAGGL
* * . * : : : * * *: : . .*
Mb1873c|M.bovis_AF2122/97 VAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEP
Rv1842c|M.tuberculosis_H37Rv VAAAAASGFSRFPVVEGDLDATVGIVHVKQVFEVPPGDRAHTLLTTVAEP
MMAR_2716|M.marinum_M VAAVAASGYSRFPVVQGDLDETFGIVHVKQVFQVPAAKRAHTLLSSIAKP
MAV_2878|M.avium_104 VTAAAESGFSRFPIVDGDLDETVGIVHVKQVFAIPRAARAHTLLTTVAQP
Mflv_3364|M.gilvum_PYR-GCK SEAAVSTGHSRFPVIHGDLDETIGMVHVKQVFEVPAVSRSTTRLADLVQP
Mvan_3094|M.vanbaalenii_PYR-1 SDAATRTGHSRFPVIRGDLDETVGMVHVKQVFAVPADARATTRLATLVQP
TH_2608|M.thermoresistible__bu IRVADETGFSRFPITRGDLDETVGMVHVKQVFEVPHDQRATTRLARLAVP
MSMEG_3637|M.smegmatis_MC2_155 MDAAIRTGFSRFPIIKGDLDETIGVVHVKQVFAVPRDKRDRVRLASLALP
MAB_2411c|M.abscessus_ATCC_199 VTIAVETGFSRFPITEGDLDATIGIVHVKQVFEVPRDRRATTTLASLARP
MUL_3269|M.ulcerans_Agy99 VGGVWLVFIGWFIFAAAREEETR--ISTQQLFTGLRVADAMTAHP-----
. . * . . : * : .:*:* . .
Mb1873c|M.bovis_AF2122/97 VAVVPSTLDGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGD
Rv1842c|M.tuberculosis_H37Rv VAVVPSTLDGDAVMAQVRASALQTAMVVDEYGGTAGMVTLEDLIEEIVGD
MMAR_2716|M.marinum_M VPVVPSTLDGDALMAQIRANSLQTAMVVDEYGGTAGMVTVEDLVEEIVGD
MAV_2878|M.avium_104 VPVVPSTLDGDAVMAEIRANSLQTALVVDEYGGTAGMVTVEDLIEEIVGD
Mflv_3364|M.gilvum_PYR-GCK LTKVPSTLDGDAVMAEVRANGLQTALVVDEYGGTAGMVTVEDLIEEIVGD
Mvan_3094|M.vanbaalenii_PYR-1 VTKVPSTLDGDAVMSEVRANGLQTALVVDEYGGTAGMVTVEDLIEEIVGD
TH_2608|M.thermoresistible__bu VIKVPSTLDGDALMTQLRGNGLQTALVVDEYGGTAGMVTVEDMIEELVGD
MSMEG_3637|M.smegmatis_MC2_155 VAKVPSTLDGDAVMTQIRANGLQTALVVDEYGGTAGMVTVEDLIEEIVGD
MAB_2411c|M.abscessus_ATCC_199 VAVVPSTLDGDAVMEQVRANGMQTALVVDEYGGTAGLVTVEDMIEEIVGD
MUL_3269|M.ulcerans_Agy99 -HTAPGWIDVDEFIARYVLGDRHSAYPVTERDGSITGLVTLRQLRELAPE
.*. :* * .: . . ::* * * .*: :. :.*:. :
Mb1873c|M.bovis_AF2122/97 VRDEHDDATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETIGGLV
Rv1842c|M.tuberculosis_H37Rv VRDEHDDATPDVVAAGNGWRVSGLLRIDEVASATGYRAPDGPYETIGGLV
MMAR_2716|M.marinum_M VRDEHDDATPDVVAAGNGWRVSGLLRIDEVAIAIGYQAPEGPYETIGGLV
MAV_2878|M.avium_104 VRDEHDDATPDVVPAGTGWRVSGLLRIDEVAAATGFRAPEGPYETIGGLV
Mflv_3364|M.gilvum_PYR-GCK VRDEHDDEPPDVVAAGQGWQVSGLLRIDEVAEGTAFRAPEGDYETIGGLI
Mvan_3094|M.vanbaalenii_PYR-1 VRDEHDVEPPDVVQAGRGWQVSGLLRIDEVAQGTEFRAPEGDYETIGGLV
TH_2608|M.thermoresistible__bu VRDEHDDATPAVVRAPHGWQVSGLLRIDEVADQTGFRPPEGDYETIGGLV
MSMEG_3637|M.smegmatis_MC2_155 VRDEHDDATPDVMPAGKGWQVSGLLRIDEVAAQTGFRAPEGEYETIGGLV
MAB_2411c|M.abscessus_ATCC_199 VRDEHDDATPDVVSSGGGWVVSGLLRIDEVAAATGYRAPEGEYETIGGLV
MUL_3269|M.ulcerans_Agy99 RRGSTTVR-------------EIALPLHDVPTATPQEPLTTLLERMAPAG
*.. . * :.:*. .. * :.
Mb1873c|M.bovis_AF2122/97 LRELGHIPVAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDSLELIK
Rv1842c|M.tuberculosis_H37Rv LRELGHIPVAGETVELTALDQDGLPDDSMRWLATVIQMDGRRIDLLELIK
MMAR_2716|M.marinum_M LRQLGHIPVAGETVELPALDEDRVPDQSVRWRATVVQMDGRRIDLLELTE
MAV_2878|M.avium_104 LREIGHIPAAGETVKLPALDPDGLLDPVLRWQARVIRMDGRRIDVLELTE
Mflv_3364|M.gilvum_PYR-GCK LEKLGHIPDEGETVELTAFDPDGAIEDPVRWLATVIKMDGRRIDQLRLTR
Mvan_3094|M.vanbaalenii_PYR-1 LEKLGHIPEEGESVELIAFDPDGPIQDPVHWLATVVKMDGRRIDQLRLTE
TH_2608|M.thermoresistible__bu LQELGHIPEAGEAVELTAFEPDGPMEDPVRWLATVVQMEGRRIDLLELVE
MSMEG_3637|M.smegmatis_MC2_155 LQELGHIPETGEAVDLTAFDPDTDADEPTHWLATVVRMDGRRIDLLELTK
MAB_2411c|M.abscessus_ATCC_199 LQELGHIPTVGETVELTAVVPDHPLAELPRWRARVAGMDGRRIDQIELTE
MUL_3269|M.ulcerans_Agy99 RGSRALVLDGGAVVGIVAASDIARLINVYRLAGPGATADS-ADQHEKYSN
. . : * * : * : . :. : . .
Mb1873c|M.bovis_AF2122/97 MG----GHADPGSGRGR-
Rv1842c|M.tuberculosis_H37Rv MG----GHADPGSGRGR-
MMAR_2716|M.marinum_M LAGAEDGQDDSDPERGGR
MAV_2878|M.avium_104 ID----AHAEAPGGRR--
Mflv_3364|M.gilvum_PYR-GCK LG---RLSDAPEGEDHRG
Mvan_3094|M.vanbaalenii_PYR-1 LG---RKGDS------RG
TH_2608|M.thermoresistible__bu LG---RGNGGPKAGVQR-
MSMEG_3637|M.smegmatis_MC2_155 LE---PAGEGEPNG----
MAB_2411c|M.abscessus_ATCC_199 LT---DADSRGNNDDG--
MUL_3269|M.ulcerans_Agy99 AG----------------