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TDAAWRCARTGPGSSLCANSLCQDVRHVRQKLRQGYPHRAAASVVALSVAAPAAPVAIVGIGCRLAGDIT TPREFWSFLLTGGSKVTEVPSERWEPYLHRDPRNAALLRETTRWGTFLDDLAGFDAEFFGVSPREAELMD PQQRLALEVSWEALEHAGISPRALVGSDTAVLMGVNSDDYGKLLMEDIAGIEAWTGIGTSLCGVANRVSH LLDLRGPSVALDAACAASLVAVHQACQLLRAGETSLALAGGVSALIGPGLTRVLDVAGATAPDGRCKTFD DDADGYGRGEGAAVVVLKLLDDAVRDGDRVLAVVRGGAVAQDGRTVGIMSPNGQAQEDLFRIACRAAGVT PASVGYLEAHGTGTPTGDPVEIGALSAVYGRGRADNPCAVGSVKPNTGHLEGGAGVVGLIKAALALHHEQ LPPTAGVRTLTTAVDWAASGLRVPTEAEPWPRAAEPRRAAVCSYGYGGTIAHVLLEEAPPAPSRETVSAQ MSFIPLSARSEARLAVQAGALAGHLRPADFSVDELAATLWTRRGHEPVRAAVLVDDGGVADGLDALATQQ RDPRVVTGSVVPGAADGAVWVFSGHGSHWPGMGRELLAGEPTFGAVIDEVDQVFRRELGFSARGALASGE LGGTDRVQALTFATQVGLAAVLRERGVAPAAVIGHSVGEVAACVVAGVFDLAHGASIACYRARGFLSVAG DGAMALARLPFDEAERRLGGRTDVVAAISASTESTVVSGTVAAVDEIVEAWTASGVMVRRVNTDVAFHSP AMDGLTGELGRLVAALPAPGRARVPLYTTALEDPRSEAARDEHYWVANLRGRVRFAEAVEAAARDGHRLF LEVSAHPVVSHSIVETLTSLGMDDHAVLPVLRRDQPQRRAVAAAVGALYCHGAPVAHGFTATMPWAADLP GTQWQHRRFWRTPTPPPNTRALHDPSSHTLLGGVVDVTGEVPARVWQTRLDMGSRPYPGDHPVRETEIVP AAVLLNTFLTAAGSGLTDVRLRTPVPPGRVRDIQVVLQDGSLRISSRLADGGDGNGWLTHSSAVVATDED FEGELNELMGGGVGADTQARCAEQLPPGHVIDTLAGVGVAAMGFGWQVLDIGRGAGELLLRVRAEADGST PRSWAGLLDAATSAASTVFDGPPRLRMPARIERVHVCGDPPAVALLHVRRRQGTATDVAIADESGAVRAS ITAMTFEELESATGADPSRMLHHVAWHVTPFCADDRPTEVAVIGGGVDIDPVVRDLSDAGVPHRVYGSPG QVPGDTGERSVVLLLPRDDSPEAAAEQVLDTLKHLCDNNSQARLWVLTNRVHEGGNLVHAPLWGMSRIAA AEHPQLWGGVLDVACGGVPLGVLASLHGHGVVVARDGVAMTARLSHAQSGGGAPMTCTPGGTYLVTGGTG ALGLRIAQRLADLGARRLVLLSRSGLPHRDQWTDNQSEAVRAVAALEERGVSVHVAAIDIGAAGAGDQLR AMLRELPPVRGVVHAAGVEAGALLLDTSADDIRAAMRPKVAGTLILHELFPPEQLDWMVLFSSCGYLAGF PGQGAYACANAFLDATARHRCALGDRTVSVAWTAWRGLGMGSTSGFVAAQLEALGMGTVGADDAMRALDT AMRGEEPNVVVLPVLPGAAAVPMLSDVAPTGRDDDDVAPVGPGDADLDEWVAREVAAAVAAELGLPESEV DPRVPLVEAGVDSIMTVALRRALEKRTGLALPPTLLWEHPTAAAVTDRIVELLTPHPEKADIS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3852 | - | - | 100% (1744) | beta-ketoacyl synthase |
| M. vanbaalenii PYR-1 | Mvan_3128 | - | 0.0 | 39.31% (1763) | beta-ketoacyl synthase |
| M. vanbaalenii PYR-1 | Mvan_3124 | - | 0.0 | 33.68% (1811) | beta-ketoacyl synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2956 | ppsA | 0.0 | 36.18% (1780) | phenolpthiocerol synthesis type-I polyketide synthase PPSA |
| M. gilvum PYR-GCK | Mflv_2690 | - | 0.0 | 78.43% (1711) | beta-ketoacyl synthase |
| M. tuberculosis H37Rv | Rv2931 | ppsA | 0.0 | 36.24% (1780) | phenolpthiocerol synthesis type-I polyketide synthase PPSA |
| M. leprae Br4923 | MLBr_02357 | - | 0.0 | 35.92% (1779) | polyketide synthase |
| M. abscessus ATCC 19977 | MAB_3148c | - | 0.0 | 34.38% (1367) | polyketide synthase Pks5 |
| M. marinum M | MMAR_3797 | - | 0.0 | 33.80% (1790) | type I modular polyketide synthase |
| M. avium 104 | MAV_2370 | - | 0.0 | 35.34% (1364) | mycocerosic acid synthase |
| M. smegmatis MC2 155 | MSMEG_6767 | - | 0.0 | 32.85% (1784) | mycocerosic acid synthase |
| M. thermoresistible (build 8) | TH_2454 | - | 0.0 | 68.14% (1764) | PUTATIVE beta-ketoacyl synthase |
| M. ulcerans Agy99 | MUL_2016 | ppsD | 0.0 | 34.10% (1827) | phenolpthiocerol synthesis type-I polyketide synthase PpsD |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3852|M.vanbaalenii_PYR-1 ---------------------------MTDAAWRCARTGPGSSLCANSLC
Mflv_2690|M.gilvum_PYR-GCK --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
Mb2956|M.bovis_AF2122/97 MTGSISGEADLRHWLIDYLVTNIGCTPDEVDPDLSLADLGVSSRDAVVLS
Rv2931|M.tuberculosis_H37Rv MTGSISGEADLRHWLIDYLVTNIGCTPDEVDPDLSLADLGVSSRDAVVLS
MLBr_02357|M.leprae_Br4923 MTASIGSEADLCHWLVNYLVTNIGCTPDEVDLNLSLTDLGMSSRDAVVLS
MUL_2016|M.ulcerans_Agy99 MTS------------------------------LAERAAQMSPKAREVLA
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MMAR_3797|M.marinum_M -------------------------------------MNTQFDKVREALR
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3852|M.vanbaalenii_PYR-1 QDVRHVRQKLRQG--------------------YPHRAAASVVALSVAAP
Mflv_2690|M.gilvum_PYR-GCK ------------------------------------------MGVNGADA
TH_2454|M.thermoresistible__bu ---------------------------------------MSVDVTAKARP
Mb2956|M.bovis_AF2122/97 GELSELLGRTVSPIDFWEHPTINALAAYLAAPEPSPDSDAAVKRGARNSL
Rv2931|M.tuberculosis_H37Rv GELSELLGRTVSPIDFWEHPTINALAAYLAAPEPSPDSDAAVKRGARNSL
MLBr_02357|M.leprae_Br4923 GELTDLLGKTVSPIDFWEHPTINALAAYLIAPAPDPESESAPRRSVQGAL
MUL_2016|M.ulcerans_Agy99 HELVRAG------------------------------------TAFPTDI
MAB_3148c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
MMAR_3797|M.marinum_M RTLVENDR----------------------------------LNRLLTAS
MSMEG_6767|M.smegmatis_MC2_155 ----------------------------------------MPMPNTDHTS
Mvan_3852|M.vanbaalenii_PYR-1 AAPVAIVGIGCRLAGDITTPREFWSFLLTGGSKVTEVPSER-WEPYLHRD
Mflv_2690|M.gilvum_PYR-GCK AEPIAVVGIGCRLAGDISTPGEFFSFLLAGDSAVTEVPPER-WEPYLHRD
TH_2454|M.thermoresistible__bu DDPIAIIGIGCRLAGRITSPEEFWGFLLAGGSNVREIPAER-WEPYLRRD
Mb2956|M.bovis_AF2122/97 DEPIAVVGMGCRFPGGISCPEALWDFLCERRSSISQVPPQR-WQPFEGGP
Rv2931|M.tuberculosis_H37Rv DEPIAVVGMGCRFPGGISCPEALWDFLCERRSSISQVPPQR-WQPFEGGP
MLBr_02357|M.leprae_Br4923 EEPIAVIGMGCRFPGGISGPEALWQFLCDRRSSIGQVPNER-WELFDDGS
MUL_2016|M.ulcerans_Agy99 AEPVAVVGIGCRLPGNVSGPDSFWQLLVDGRDAVDEVPADR-WDADAFYD
MAB_3148c|M.abscessus_ATCC_199 --------MGCRLPGGIESPEQFWQALLRGEDFITEVPPAR-WDLTEYYD
MAV_2370|M.avium_104 MVPVAVIGMACRLPGAVDSPERLWEALLRGDDFVTEIPPDR-WDADEYYD
MMAR_3797|M.marinum_M FEPVAIVGMGCRYPGGLASGDALWEAVLGGRDVVSSFPTDRGWDVEGLFD
MSMEG_6767|M.smegmatis_MC2_155 RQPLAIVGIGCRFPGGADSAQRYWDLLCNNIDATREVPENR-WNAAKYHD
:.** .* : : . ..* * *:
Mvan_3852|M.vanbaalenii_PYR-1 PRNAALLRETTRWGTFLDDLAGFDAEFFGVSPREAELMDPQQRLALEVSW
Mflv_2690|M.gilvum_PYR-GCK PRNAAVLRETTRWGSFLDDLPGFDAEFFGVSPREAELMDPQQRLALEVSW
TH_2454|M.thermoresistible__bu PRNAAVLREITPWGTFLDDLAGFDAEFFGVSPREAELTDPQQRLALEVSW
Mb2956|M.bovis_AF2122/97 PEVAAALARTTRWGSFLPDIDAFDAEFFEISPSEADKMDPQQRLLLEVAW
Rv2931|M.tuberculosis_H37Rv PEVAAALARTTRWGSFLPDIDAFDAEFFEISPSEADKMDPQQRLLLEVAW
MLBr_02357|M.leprae_Br4923 PEVKALLARTTRWGSFLEDIDAFDSEFFEISPSEADKMDPQQRLLLEVAW
MUL_2016|M.ulcerans_Agy99 PDPRAPGRMTTKWGGFIDDVAGFDADFFGITPREAVAMDPQQRVLLEVAW
MAB_3148c|M.abscessus_ATCC_199 PESGVPGKSPSKWGAFLEDVGGFDADFFSINEREAVSIDPQHRVLLETSW
MAV_2370|M.avium_104 PEPGVPGRSVSRWGAFIDDVAGFDPEFFGINEREATAMDPQHRLLLETSW
MMAR_3797|M.marinum_M PDPDAVGKSYTRSGGFLYEAADFDAEFFGISPREALAMDPQQRLILEVSW
MSMEG_6767|M.smegmatis_MC2_155 PNPAKIGKIVTRRGGFLDQIDQFDPQFFGISPREAHSLDPQQRLLLQATW
* : * *: : **.:** :. ** ***:*: *:.:*
Mvan_3852|M.vanbaalenii_PYR-1 EALEHAGISPRALVGSDTAVLMGVNSDDYGKLLMED---IAGIEAWTGIG
Mflv_2690|M.gilvum_PYR-GCK EALEHAGIPPRSLAGSDTAVLMGVNSDDYGKLIMED---LAGIEAWTGIG
TH_2454|M.thermoresistible__bu EALEHAGVPPRSLAGTDTAVLMGVNSDDYGRLLMED---LPGIEAWTGIG
Mb2956|M.bovis_AF2122/97 EALEHAGIPPGTLRRSATGVFAGACLSEYGAMASAD---LSQVDGWSNSG
Rv2931|M.tuberculosis_H37Rv EALEHAGIPPGTLRRSATGVFAGACLSEYGAMASAD---LSQVDGWSNSG
MLBr_02357|M.leprae_Br4923 EALEHAGISSNSLRRSQTGVFAGSCLSEYGAIASTD---LSQVDGWSNTG
MUL_2016|M.ulcerans_Agy99 EALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLER---RAEIDAYISTG
MAB_3148c|M.abscessus_ATCC_199 QAVEHAGIDPRALAGSQTGVFVGVTHNDYQLVAADA---ADLGGPYGFAG
MAV_2370|M.avium_104 EAMEHAGLTEERVADSRTGVFIGLTHGDYQLLAADT---RSVEGAYGFSG
MMAR_3797|M.marinum_M EALEHAGIDPLALAGSATGVFTGVMYHDYAARLFGTGG-ASGVEGYLGSG
MSMEG_6767|M.smegmatis_MC2_155 EALEDGGIPADELAGTDVGVFVGGFTLDYQLLQNQGRTSRYRFKPHSATG
:*:*..*: : : .... * :* *
Mvan_3852|M.vanbaalenii_PYR-1 TSLCGVANRVSHLLDLRGPSVALDAACAASLVAVHQACQLLRAGETSLAL
Mflv_2690|M.gilvum_PYR-GCK TSLCGVANRVSHLLDLRGPSVALDAACAASLVAVHQACQLLRAGETSLAL
TH_2454|M.thermoresistible__bu TSLCGIANRVSHLLDLRGPSVALDAACAASLVAVHNACQLLRAGETGLAI
Mb2956|M.bovis_AF2122/97 GAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIHLACQSLRTQDCHLAI
Rv2931|M.tuberculosis_H37Rv GAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIHLACQSLRTQDCHLAI
MLBr_02357|M.leprae_Br4923 GAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIHLACQSLRTADANLAI
MUL_2016|M.ulcerans_Agy99 NPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRESDVAL
MAB_3148c|M.abscessus_ATCC_199 TNFCMASGRISYALGVHGPSLTVDAGCAAGLATVHMGCQSLAAGESDLVL
MAV_2370|M.avium_104 SNFSLASGRIAYALGVHGPALTVDTACSSGLTAIHLACRSLHEGESDLAL
MMAR_3797|M.marinum_M SAGSVISGRVAYVLGLQGPAVSVDTACSSSLVALHLAVQALRSGECDLAL
MSMEG_6767|M.smegmatis_MC2_155 MMMTMLANRISHAFDFRGPSMAIDTACSSSLVAVHLAAQSIWDGDCDVAL
.*::: :..:**::::*:.*::.*.::* . : : : :.:
Mvan_3852|M.vanbaalenii_PYR-1 AGGVSALIGPGLTRVLDVAGATAPDGRCKTFDDDADGYGRGEGAAVVVLK
Mflv_2690|M.gilvum_PYR-GCK AGGVSALIGPGLTRVLDVAGATAPDGRCKTFDDAADGYGRGEGAGVVVLK
TH_2454|M.thermoresistible__bu AGGVSALIGPGLTRVLDKAGATAPDGRCKSFDASADGYGRGEGAAVVILK
Mb2956|M.bovis_AF2122/97 AAGVNLLLSPAVFRGFDQVGALSPTGQCRAFDATADGFVRGEGAGVVVLK
Rv2931|M.tuberculosis_H37Rv AAGVNLLLSPAVFRGFDQVGALSPTGQCRAFDATADGFVRGEGAGVVVLK
MLBr_02357|M.leprae_Br4923 AAGVNLLLSPAVFRGFDQVGALSPTGCCRAFDAAADGFVRGEGAGVVVLK
MUL_2016|M.ulcerans_Agy99 AGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGVVVLK
MAB_3148c|M.abscessus_ATCC_199 AGGVNLVLEPRRYVGASQQRMLSPTGRCHTFTGEADGFVMSEGCVMVLLK
MAV_2370|M.avium_104 AGGATLALDPRKFSAGSAEGMLSPTGRCHAFDVAADGFVGGEGSVMLLLK
MMAR_3797|M.marinum_M AGGVTVMATPTTFVEFSRQRGVAVDGRCKSFAAAADGTGWGEGVGVVVVE
MSMEG_6767|M.smegmatis_MC2_155 AGGVNIMVGPNTAIAESKSGFLSPEGRSKAFSDTADGYARGEGGAVVVIK
*.*. * . : * .::* *** .** :::::
Mvan_3852|M.vanbaalenii_PYR-1 LLDDAVRDGDRVLAVVRGGAVAQDGRTVGIMSPNGQAQEDLFRIACRAAG
Mflv_2690|M.gilvum_PYR-GCK RLADALRDGDRVLAVVRGGAVAQDGRTVGIMSPNGEAQADLFRLACRAAG
TH_2454|M.thermoresistible__bu RLPDALRDGDRVIAVIRGGAVAQDGRTVGIMSPNGAAQRDLFRHTCEITG
Mb2956|M.bovis_AF2122/97 RLTDAQRDGDRVLAVICGSAVTQDGRSNGLMAPNPAAQMAVLRAAYTNAG
Rv2931|M.tuberculosis_H37Rv RLTDAQRDGDRVLAVICGSAVNQDGRSNGLMAPNPAAQMAVLRAAYTNAG
MLBr_02357|M.leprae_Br4923 RLTDAQRDGDRVLAIIRGSAVNQDGRSNGLMAPNPAAQVAVLRTAYANAA
MUL_2016|M.ulcerans_Agy99 RLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTALKLAD
MAB_3148c|M.abscessus_ATCC_199 RLDDAVRDGDRILAVVRGTASNQDGRTVNQSTPSSEAQAAACRTALAVAG
MAV_2370|M.avium_104 RLNDALRDGDRILAVVRGTAANQDGHTVNIATPSKTAQTAVYRAALAAAG
MMAR_3797|M.marinum_M RLSDARRLGHSVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALANAE
MSMEG_6767|M.smegmatis_MC2_155 PLAHALRDGDDIYAQILGTAVSQDGHTDGITVPNEEAQEAAIRMALQRAG
* .* * *. : * : * * *** : . *. :* : :
Mvan_3852|M.vanbaalenii_PYR-1 VTPASVGYLEAHGTGTPTGDPVEIGALSAVYGR-G-RADNPCAVGSVKPN
Mflv_2690|M.gilvum_PYR-GCK VSPESVGYLEAHGTGTPTGDPVEVGALSEVYG----RADDPCALGSVKPN
TH_2454|M.thermoresistible__bu TSPATVDFVEAHGTGTPTGDPVELDALAAVYGA-AHGPDDPCRVGSVKPN
Mb2956|M.bovis_AF2122/97 MQPSEVDYVEAHGTGTLLGDPIEARALGTVLGRGRPE-DSPLLIGSVKTN
Rv2931|M.tuberculosis_H37Rv MQPSEVDYVEAHGTGTLLGDPIEARALGTVLGRGRPE-DSPLLIGSVKTN
MLBr_02357|M.leprae_Br4923 MPPTAIDYVETHGTGTLLGDPIEARALGAVLGRGRAE-DSPLLIGAVKTN
MUL_2016|M.ulcerans_Agy99 ATADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGSVKTN
MAB_3148c|M.abscessus_ATCC_199 VEADTVGLIEAHGTGTPVGDPIEYTGLAQVYG-----VDGPCAVGSVKTN
MAV_2370|M.avium_104 VDAGTVGMVEAHGPGTPVGDPIEYASLAEVYG-----IDGPCALASVKTN
MMAR_3797|M.marinum_M VRAAEVDVVEAHGTGTTLGDPIEAQALLATYGQ-DRPADRPLWLGSVKSN
MSMEG_6767|M.smegmatis_MC2_155 VEPNDVAYVEAHGTGTPVGDPIEMRALAGALTT-DRDATRPLVIGSVKTN
. : :*:**.** ***:* .* . . :.:**.*
Mvan_3852|M.vanbaalenii_PYR-1 TGHLEGGAGVVGLIKAALALHHEQLPPTAGVRTLTTAVDWAASGLRVPTE
Mflv_2690|M.gilvum_PYR-GCK VGHLEGGAGVVGLIKTVLALHHEMLPPTAGVRTLTTAVDWAGSGLRVPTE
TH_2454|M.thermoresistible__bu TGHLEGGAGVVGLIKAALALQHGVIPPTAGIRELTPAVDWATNGLHVPTT
Mb2956|M.bovis_AF2122/97 LGHTEAAAGIAGFIKTVLAVQHGQIPPNQHFETANPHIPFTDLRMKVVDT
Rv2931|M.tuberculosis_H37Rv LGHTEAAAGIAGFIKTVLAVQHGQIPPNQHFETANPHIPFTDLRMKVVDT
MLBr_02357|M.leprae_Br4923 LGHLEAAAGIAGFIKTVLAVQRGQIPPNQRFESPNLHIPFAELRMKVVDK
MUL_2016|M.ulcerans_Agy99 LGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLFVPTQ
MAB_3148c|M.abscessus_ATCC_199 FGHTMSAAGALGLMKIVLAVEHGVVPPNLHFTGIPDKLAPVKTNLFVPQT
MAV_2370|M.avium_104 FGHAQAASGALGMMKAILALQHGVVPRNLHFTQLPDDLARIDTKLFVPQQ
MMAR_3797|M.marinum_M MGHTQAAAGVAGVIKMIQAMRHQVMPRSLHVDSPSPHVDWASGAVELLTE
MSMEG_6767|M.smegmatis_MC2_155 IGHLEAGAGVAGLIKAALIVKHGHIPANLHLKNPTRHVSLTELKLDIPTI
** ..:* ..:* : : :* . . : : :
Mvan_3852|M.vanbaalenii_PYR-1 AEPWPR-AAEPRRAAVCSYGYGGTIAHVLLEEAPPAPSR-----------
Mflv_2690|M.gilvum_PYR-GCK AQPWPR-GGAPRRAAVCSYGYGGTIAHVLLEEAPITADP-----------
TH_2454|M.thermoresistible__bu VEPFPRRADSPRRAAVCSYGYGGTIAHLLLEEAPAVDETPAAAPAPAADA
Mb2956|M.bovis_AF2122/97 QTEWPATGH-PRRAGVSSFGFGGTNAHVVIEQGQEVRPAPG---------
Rv2931|M.tuberculosis_H37Rv QTEWPATGH-PRRAGVSSFGFGGTNAHVVIEQGQEVRPAPG---------
MLBr_02357|M.leprae_Br4923 HMEWPDTGH-LRRAAVSSFGFGGTNAHVVIEQGPELTPVTE---------
MUL_2016|M.ulcerans_Agy99 GAQWPAG---LRRAAVSSFGLSGTNAHVVLEQPP--APAPA---------
MAB_3148c|M.abscessus_ATCC_199 VIPWPGKAQGPRRAGVSAYGMSGSNVHAVVEQAPPVESSTPPA-------
MAV_2370|M.avium_104 TTPWVSNGGHPRRAAVSSYGLSGTNVHAILEQAPEPAPETVAP-------
MMAR_3797|M.marinum_M QRDWSVQDGRPRRAGVSSFGVSGTNAHVILEEAPAESVPGHGS-----DS
MSMEG_6767|M.smegmatis_MC2_155 GRPFPECDR--RIAGINSFGFGGTNAHVVLAEPPAARHSAETG-------
: * *.: ::* .*: .* :: :
Mvan_3852|M.vanbaalenii_PYR-1 -ETVSAQMSFIPLSARSEARLAVQAGALAGHLRP--ADFSVDELAATLWT
Mflv_2690|M.gilvum_PYR-GCK -DTSTAPTAFIPMSARSEARLAAAADALAGHLRE--AAFVVDDVAATMWT
TH_2454|M.thermoresistible__bu ADANSPRFHVIPVSARSGARLARHAAALRGHLS---AGADLTAVAATMWQ
Mb2956|M.bovis_AF2122/97 -QGLSPAVSTLVVAGKTMQRVSATAGMLADWMEGPGADVALADVAHTLNH
Rv2931|M.tuberculosis_H37Rv -QGLSPAVSTLVVAGKTMQRVSATAGMLADWMEGPGADVALADVAHTLNH
MLBr_02357|M.leprae_Br4923 -CSSNTAVSTLVVTGKTASRVAAMAGMLADWVEGPGAEVALADVAHTLNH
MUL_2016|M.ulcerans_Agy99 -DQPRSGLSALVVSGKTPQRVAAMASALADWVDGPGAQTPLADVAHTLNH
MAB_3148c|M.abscessus_ATCC_199 VESPLGSQLIFPVSSTSAEELRRTAARLADWVAER-PEVAPGDVGYTLAR
MAV_2370|M.avium_104 EGISAESPLLFPLSSTSADELRRTAGRLADWVHAH-GDLALPDLAYTLAR
MMAR_3797|M.marinum_M GAASAWPVVPWVVSGKSDQALAAQAGRLGAYLADH-PDLAVADVGFSLAS
MSMEG_6767|M.smegmatis_MC2_155 ---DHRVLTVLPISARSEEALVATAGRLAGHLAAH-PEVTLADLGYTLSH
::. : : * * : :. ::
Mvan_3852|M.vanbaalenii_PYR-1 RRGHEPVRAAVLVD-------DGGVADGLDALATQQRDPRVVTGSVVPGA
Mflv_2690|M.gilvum_PYR-GCK RRSHDPVRGAVVTDGLSGAQAAEAAVAALDVIAARGRDARVVTGHVVPGA
TH_2454|M.thermoresistible__bu RRSHEPVRAAVIAR------HPGELVAGLDAIATDTRHPAVVAGSVLPAA
Mb2956|M.bovis_AF2122/97 HRSRQPKFGTVVAR------DRTQAIAGLRALAAGQHAPGVVN-PAEGSP
Rv2931|M.tuberculosis_H37Rv HRSRQPKFGTVVAR------DRTQAIAGLRALAAGQHAPGVVN-PADGSP
MLBr_02357|M.leprae_Br4923 HRSRHAKFGTVVAR------DRIQAVAGLRALAAGKQAPGVVG-QQDGTP
MUL_2016|M.ulcerans_Agy99 HRARHGKFGAVVAR------DRAGAVEGLRALAAGQPGPGVLG-CQDVQN
MAB_3148c|M.abscessus_ATCC_199 RRAHRSVRTAVVAD------GADELIDALRGVAEG----DAPYPAAVAQD
MAV_2370|M.avium_104 RRVHRPVRTAVLAG------DRAQLIEALREVADG----DTPYPAAVGRG
MMAR_3797|M.marinum_M HRSGLEYRGAVIGA------DHGELVAGLAALADGQPSASVVTGRVLAG-
MSMEG_6767|M.smegmatis_MC2_155 RRAHLNHRHTFVVD------SIDEARRQLQAVADGG------QISAGRAG
:* :.: * :*
Mvan_3852|M.vanbaalenii_PYR-1 ADGAVWVFSGHGSHWPGMGRELLAGEPTFGAVIDEVDQVFRRELGFSARG
Mflv_2690|M.gilvum_PYR-GCK ETGAVWVFSGHGSHWAGMGRELLMTEPAFAATIDEVDIVFARELGFSARV
TH_2454|M.thermoresistible__bu EAGAVWVFSGHGSHWPGMGRELLEHEPVFAAVIDEIEPVFRAELGFSPRQ
Mb2956|M.bovis_AF2122/97 GPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEPVFVEQAGFSLHD
Rv2931|M.tuberculosis_H37Rv GPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEPVFVEQAGFSLHD
MLBr_02357|M.leprae_Br4923 GSGTVFVYSGRGSQWAGMGRQLLADEPAFTAAVAELEPVFVVHAGFSLHD
MUL_2016|M.ulcerans_Agy99 QPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQAGFSLQQ
MAB_3148c|M.abscessus_ATCC_199 DRGPVWLFSGQGSQWAGMGAELLGKEPVFAETIARLEPLIHAESGFSVTD
MAV_2370|M.avium_104 DRGPVWVFSGQGSQWAAMGADLLATEPVFAATVAQAEPLIARESGFSVAE
MMAR_3797|M.marinum_M --KTTFVFPGQGGQWQSMAVELLDSAPVFATQLRACADALAPYVDWSLDA
MSMEG_6767|M.smegmatis_MC2_155 EARLAFVCTGMGPQWWQMCRGLLDVFPVFTDSIHRTDRELSRYADWSLLE
.:: .* * :* * ** * * : : .:*
Mvan_3852|M.vanbaalenii_PYR-1 ALASG-ELGGT---DRVQALTFATQVGLAAVLRERGVAPAAVIGHSVGEV
Mflv_2690|M.gilvum_PYR-GCK ALTAE-DLGGT---DRVQALTFAMQVGLAAVLRSRGVTPAAVIGHSVGEV
TH_2454|M.thermoresistible__bu ALQSG-ELGGT---DRVQALTFAVQAGLAAVLRDRGVKPAAVIGHSVGEV
Mb2956|M.bovis_AF2122/97 VLANGEELVGI---EQIQLGLIGMQLALTELWCSYGVQPDLVIGHSMGEV
Rv2931|M.tuberculosis_H37Rv VLANGEELVGI---EQIQLGLIGMQLALTELWCSYGVRPDLVIGHSMGEV
MLBr_02357|M.leprae_Br4923 VLANGKELVGI---EQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSLGEV
MUL_2016|M.ulcerans_Agy99 TLTEGREVVGI---DRIQPVLVGIQLALTALWRSHGVTPDAVVGHSMGEV
MAB_3148c|M.abscessus_ATCC_199 AISAPETVTGI---DRVQPTLFAMQVSLAATLASYGVRPGAVIGHSMGEV
MAV_2370|M.avium_104 AMSAPQTVTGQ---DRVQPTLFTMQVALAATMKAHGVRPGAVIGHSLGEA
MMAR_3797|M.marinum_M VLRGGVAESALTRVDVVQPALFAVMVSMAALWRSCGVQPDMVIGHSQGEI
MSMEG_6767|M.smegmatis_MC2_155 ELTRDEASSRMGETEFAQPANFAIQVALAEQLAHFGITPDAVIGHSAGEV
: : * . :: *: * *:*** **
Mvan_3852|M.vanbaalenii_PYR-1 AACVVAGVFDLAHGASIACYRARGFLSVAGDGAMALARLPFDEAERRLGG
Mflv_2690|M.gilvum_PYR-GCK AACVVSGVFDLAHGAAVACHRARGFRSVMGKGAMALVRLPFDEAERRLAG
TH_2454|M.thermoresistible__bu AACVAAGVFDLARGAAVACYRARGFRSVAGKGAMALVGLPFEDARQRLGE
Mb2956|M.bovis_AF2122/97 AAAVVAGALTPAEGLRVTATRSRLMAPLSGQGGMALLELDAPTTEALIAD
Rv2931|M.tuberculosis_H37Rv AAAVVAGALTPAEGLRVTATRSRLMAPLSGQGGMALLELDAPTTEALIAD
MLBr_02357|M.leprae_Br4923 AAAVVAGALTAAEGLRVTATRSRLMAPLSGQGGMALLELDAVETEALIVD
MUL_2016|M.ulcerans_Agy99 SAAVVAGALTPADGFKVIATRSRLMARLAGQGAMALLELDSDAAEALIAD
MAB_3148c|M.abscessus_ATCC_199 AAAVVSEALSLEDGVKVICRRSQLMLRISGAGAMASVDLPAQQVVSELAD
MAV_2370|M.avium_104 AAAVVAGALSLEDGARVICRRSRLMSRVAGTGATASVELPAQQVLSELTA
MMAR_3797|M.marinum_M AAAYVAGGLSLADAARVVTARSQAIVELAGTGGMASVGLPIDQVVDRLTP
MSMEG_6767|M.smegmatis_MC2_155 AAHHIAGLLTFEQAVHVIYHRSRLQQRTTGQGRMLAVGLDAETLMQILDE
:* : : . : *:: * * * :
Mvan_3852|M.vanbaalenii_PYR-1 R------TDVVAAISASTESTVVSGTVAAVDEIVEAWTASGVMVRRVNTD
Mflv_2690|M.gilvum_PYR-GCK R------TDVVAAISASTESTVVSGTVAAVDGIVDAWTADGMTVRRVNTD
TH_2454|M.thermoresistible__bu R------TDVVAAISASPLSTVISGTVDAVGEVSAAWAEQGVMVRKVNTD
Mb2956|M.bovis_AF2122/97 F------PQVTLGIYNSPRQTVIAGPTEQIDELITRVRARDRFASRVNIE
Rv2931|M.tuberculosis_H37Rv F------PQVTLGIYNSPRQTVIAGPTEQIDELIARVRAQNRFASRVNIE
MLBr_02357|M.leprae_Br4923 Y------SQVTLAIYNSPRQTVIAGPTEQIDELIDRVRAQNRFASRVNIE
MUL_2016|M.ulcerans_Agy99 Y------PQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRLARRIEVD
MAB_3148c|M.abscessus_ATCC_199 RDI----HDVVLAVVASPQSTVVGGATETVRQLIAEWSDRGLMAREVAVD
MAV_2370|M.avium_104 RGI----SDVVVAVVASPQSTVIAGAAPTVRDLVTAWQERGVMAREVPTD
MMAR_3797|M.marinum_M WD-----GQIAVAAHNSPISTVVTGDPAAVQEFVTGCAGEGIFARLIPVD
MSMEG_6767|M.smegmatis_MC2_155 KILDQFGRRVSVAAINSPSAVTVAGDADVLEDIARHLDEAQIFNRYLAVK
: . *. .: * : . : .
Mvan_3852|M.vanbaalenii_PYR-1 VAFHSPAMDGLTGELGRLVAALPAPGRARVPLYTTALEDPRSEAARDEHY
Mflv_2690|M.gilvum_PYR-GCK VAFHSPAMDALTADLAAMVAQLPQPDSAHIPLYTTALEDPRSTAPRGPDY
TH_2454|M.thermoresistible__bu VAFHSPAMDALTAELARLTSTLT-PKPAAVPLYSTALADPRSTAARDEHY
Mb2956|M.bovis_AF2122/97 VAPHNPAMDALQPAMRSELADLT-PRTPTIGIISTTYADLHTQPVFDAEH
Rv2931|M.tuberculosis_H37Rv VAPHNPAMDALQPAMRSELADLT-PRTPTIGIISTTYADLHTQPVFDAEH
MLBr_02357|M.leprae_Br4923 VAPHNPAMDALQPQMRSELADVA-PRTPTIPILSTTYADLGSCPVFDAQH
MUL_2016|M.ulcerans_Agy99 VASHHPIIDPILPDLRSALADLT-PQPPAIPMITTTCE--QPQPVLDADY
MAB_3148c|M.abscessus_ATCC_199 VASHSPQVDPILDDLADALEDLT-PRTPVVPLYSSVSFDPRERPIMDADY
MAV_2370|M.avium_104 VAFHSPQVDPIMDDLTDALAEIS-PRPPEVPYYSATLFDPREQPVCDARY
MMAR_3797|M.marinum_M YASHSSHVEAVQDRLIGQLSSIT-PRVGEIPFYSTVTGTQIPTDTLDGGY
MSMEG_6767|M.smegmatis_MC2_155 VPYHTHYMETIKDDLHTAFASLS-SKAATLPLYSTVTGELLDRYDAGAAY
. * :: : : :. . : ::. . :
Mvan_3852|M.vanbaalenii_PYR-1 WVANLRGRVRFAEAVEAAARDG---HRLFLEVSAHPVVSHSIVETLTSLG
Mflv_2690|M.gilvum_PYR-GCK WAVNLRGRVRFAEAVRAAAEDG---HRLFLEVSAHPVVSHSIAETLLGLG
TH_2454|M.thermoresistible__bu WVANLRGRVRFAEAVTAAAEDG---HRLFLEVSAHPVVCHSMAETLALAE
Mb2956|M.bovis_AF2122/97 WATNMRNPVHFQQAIASAGSGADGAYHTFIEISAHPLLTQAIIDTLHSAQ
Rv2931|M.tuberculosis_H37Rv WATNMRNPVRFQQAIASAGSGADGAYHTFIEISAHPLLTQAIIDTLHSAQ
MLBr_02357|M.leprae_Br4923 WATNMRNPVHFQQAIMTAGT----DHRTFIEISAHPLLTQAITDTLH---
MUL_2016|M.ulcerans_Agy99 WAANLRNPVRFHQAITTAGA----QHHTFVEISPHPLLTHAITDTLAAAD
MAB_3148c|M.abscessus_ATCC_199 WVDNLRHTVRFAAAVQAALDDG---YRVFGELAPHPLLVYPAEQTARSLD
MAV_2370|M.avium_104 WANNMRRMVRFATAVQAALEDG---YRVFAELAPHPLLVRALEQTARSRE
MMAR_3797|M.marinum_M WYRNLRQRVEFERATTALLAEG---ARSFIEMGPHPVLTVAISETAEAHY
MSMEG_6767|M.smegmatis_MC2_155 WWQNTRATVLFEPAMRRMLDDG---YTHFVELGPHPVLAASILESAGTQR
* * * * * * * *:..**:: . ::
Mvan_3852|M.vanbaalenii_PYR-1 MDDHAVLPV--LRRDQPQRRAVAAAVGALYCHGAPV--AHGFTATMPWAA
Mflv_2690|M.gilvum_PYR-GCK FGEHAVLPV--LRRDQPERRAVGAAVAGLYCHGAPV--AHGLTPTTRWAA
TH_2454|M.thermoresistible__bu VGEHAVLPV--LRREQPELPAVAAVVGALYCHGAPV--RPAFPPGTRWAT
Mb2956|M.bovis_AF2122/97 PGARYTSLG--TLQRDTD--DVVTFRTNLNKAHTIH--PPHTPHPPEPHP
Rv2931|M.tuberculosis_H37Rv PGARYTSLG--TLQRDTD--DVVTFRTNLNKAHTIH--PPHTPHPPEPHP
MLBr_02357|M.leprae_Br4923 -GTRCISIG--TLQRDAD--DTVTFHTNLNNVHTVH--PPHTPHPAEPHV
MUL_2016|M.ulcerans_Agy99 SRTRLITA---TLQRDGD--DAITFHTNLAAVGKKP--ADAVTG---QLA
MAB_3148c|M.abscessus_ATCC_199 IPMVALAGM--RREQELP-HGLRDFVGDLYTAGGAV--DFSVLYPTGQLV
MAV_2370|M.avium_104 IPMAALAGM--RRGQALP-HGLRGFVADLHNAGAAV--DFSVLYPTGRLV
MMAR_3797|M.marinum_M EDRASVAVLGSLRRDEGDWQRFITSLAEAHVHGVAVDWAAVFAAHRPRRV
MSMEG_6767|M.smegmatis_MC2_155 VSVDASQRR-----GQDDARTLLNCVGALHSRGHEVAWDMVQPRAGAHPV
Mvan_3852|M.vanbaalenii_PYR-1 DLPGTQWQHRRFWRTPTPPP---NTRALHDPSSHTLLGGVVDVTGEVP--
Mflv_2690|M.gilvum_PYR-GCK DLPGTQWQHRRFWRTPTPPP---GTAALHDPASHTLLGGVADVTGEVP--
TH_2454|M.thermoresistible__bu GLPGTQWQHRRFWRTPGTPP---GGVGVHDVDSHTLLGGRIDVAGAVP--
Mb2956|M.bovis_AF2122/97 PIPTTPWQHTRHWITTKYPA---GSVGSAP-RAGTLLGQHTTVATVSASP
Rv2931|M.tuberculosis_H37Rv PIPTTPWQHTRHWITTKYPA---GSVGSAP-RAGTLLGQHTTVATVSASP
MLBr_02357|M.leprae_Br4923 TIPSTPWQHTRHWIPRKRSV---NSIGLAP-QVGTLLGQHT---AVSGIL
MUL_2016|M.ulcerans_Agy99 DIPVTPWQHTQFWVEDR------SGISELV-AAHPLLGVHIEVPSGHD--
MAB_3148c|M.abscessus_ATCC_199 DVPLPSWTRRSYLLDLSAQAQ--QGHGTHTVAVHPLLGAHVRLAEEPE--
MAV_2370|M.avium_104 DAPLPTWTHRRLWLTDGGLES--PTHGGCTVAVHPLLGPHVHLQEEPE--
MMAR_3797|M.marinum_M DLPTYAFQRQRYWLDARTTGAGDVSSVGLVEVGHPFLRAGVSLGDERG--
MSMEG_6767|M.smegmatis_MC2_155 KLPSYPWQTKRFWNDTHEAE-----EALFYRPVHPLLGQPVR--AVHP--
* : .:*
Mvan_3852|M.vanbaalenii_PYR-1 -ARVWQTRLDMGSRPYPGDHPVRETEIVPAAVLLNTFLTAAGS-------
Mflv_2690|M.gilvum_PYR-GCK -ARVWQTRLDMGNRPYPGDHPVQQTEIVPAAVLLNTFLNAAGA-------
TH_2454|M.thermoresistible__bu -ARVWQTRLDLSTRPYPGDHPVQGTEIVPAAVLLNTFLTAAGS-------
Mb2956|M.bovis_AF2122/97 PSHLWQARLAPDAKPYQGGHRFHQVEVVPASVVLHTILSAATELGYS---
Rv2931|M.tuberculosis_H37Rv PSHLWQARLAPDAKPYQGGHRFHQVEVVPASVVLHTILSAATELGYS---
MLBr_02357|M.leprae_Br4923 PIHLWQARLAPQAKPYRGWHRVHGVEVVPASIVLRTILCAAAELGYS---
MUL_2016|M.ulcerans_Agy99 --HVWQADVGTKACPWLGDHKVFGQAIMPAAGFAEIALAAASEAFDLPVD
MAB_3148c|M.abscessus_ATCC_199 -RHIWQADVGTVGQPWIADHQVRHVAVYPGAAYCEMALSAAAAVFGE---
MAV_2370|M.avium_104 -RHLWQADVGTAAQPWLADHQIRNVVVLPGAAYCEMALAAARSVLGA---
MMAR_3797|M.marinum_M --WLFSGRLSAQTHAWLADHAVFDTVLLPGAALAELALVAGGHIGLDCLE
MSMEG_6767|M.smegmatis_MC2_155 ---TWEAEFSTLTVPFLADHQVQGSVVVPGAVYVEMALAAGRETYGS---
:. . .: . * . : *.: . * *.
Mvan_3852|M.vanbaalenii_PYR-1 --GLTDVRLRTPVPPGRVRDIQVVLQDGSLRISSRLAD-GGDGNG-----
Mflv_2690|M.gilvum_PYR-GCK --GLADVRLRTPVPPGRTRDIQVVLQGRSLRLSSRLTGTEAVENG-----
TH_2454|M.thermoresistible__bu --DIADVRLRTPVAPARTRDVQVVLQDRALALASRIVGEDTTARATAGRD
Mb2956|M.bovis_AF2122/97 --ALSEVRFEQPIFADRPRLIQVVADNRAISLAS-SPAAGTPSDR-----
Rv2931|M.tuberculosis_H37Rv --ALSEVRFEQPIFADRPRLIQVVADNRAISLAS-SPAAGTPSDR-----
MLBr_02357|M.leprae_Br4923 --TLFEIRFEQPIFANLPRLIQVVVDNQLISLAS-SPATETPQHR-----
MUL_2016|M.ulcerans_Agy99 ALSINQLEIEQMLDLDEHTQVTTQLTRRADDKTR-IEIYSRSASG-----
MAB_3148c|M.abscessus_ATCC_199 GSAVQSISFEQLLTLGESTPISATATAKSADILEFVVETHDEGDV-----
MAV_2370|M.avium_104 TAEVRDIRFEQALLLDEQTTVDASASVSSPGVLHFTVQSHQGGEQ-----
MMAR_3797|M.marinum_M ELVLQAPLVPEHAAMQLQLLLGEPDEQNRRQLSIYSRPENVADRG-----
MSMEG_6767|M.smegmatis_MC2_155 DLSVDNLVLHRAVILDDTCDPVIRTTVDQDDGSVEFAALIATADT-----
: .
Mvan_3852|M.vanbaalenii_PYR-1 ------------------------WLTHSSAVVATDED-FEGELNELMGG
Mflv_2690|M.gilvum_PYR-GCK ------------------------WLTHSSAVVATDEE-FGEPIDERVWT
TH_2454|M.thermoresistible__bu TTDRDTTACDTTDRDTTACDDPGVWLTHCTARVADDHVGAEGVLDEEAIR
Mb2956|M.bovis_AF2122/97 ------------------------WTRHVTAQLSSSPSDSASSLNEHHRA
Rv2931|M.tuberculosis_H37Rv ------------------------WTRHVTAQLSSSPSDSASSLNEHHRA
MLBr_02357|M.leprae_Br4923 ------------------------WTRHVTAQLSSASARSAVPSDHPDQI
MUL_2016|M.ulcerans_Agy99 ------------------------WRRHAVAKAETSTPSAAPVLEERTSR
MAB_3148c|M.abscessus_ATCC_199 -------------------------VKRATAVLGNGGDVDMPIAYDLSAL
MAV_2370|M.avium_104 -------------------------ARHASAVLG-AATDEQPAAHDLSAL
MMAR_3797|M.marinum_M -------------------AQQGRWVQHATGTLGAGGSGEGAGFARLSMA
MSMEG_6767|M.smegmatis_MC2_155 ---------------------DLKWVITATAELNTLPRAPRAGDTGGGAV
.
Mvan_3852|M.vanbaalenii_PYR-1 GVGADTQARCAEQLPPGHVIDTLAGVGVAAMGFGWQVLDIG---RGAGEL
Mflv_2690|M.gilvum_PYR-GCK --------RCAESLPAGHVVDTLAGVGVAAMGFDWQVRDMR---RGSGEL
TH_2454|M.thermoresistible__bu -------ARCPQPLPAGHVVDTLAGLGVAAMGFGWEVLELH---RGEGEL
Mb2956|M.bovis_AF2122/97 NGQP---PERAHRDLIPDLAELLAMRGIDGLPFSWTVASWT---QHSSNL
Rv2931|M.tuberculosis_H37Rv NGQP---PERAHRDLIPDLAELLAMRGIDGLPFSWTVASWT---QHSSNL
MLBr_02357|M.leprae_Br4923 NG-----HLEVISDPIPDVASLLALCGVDGLPFEWSVKSWAKKTQQSTSR
MUL_2016|M.ulcerans_Agy99 QDET---DIKP-----ADLYALLRQAGQNHGPAFAALTRILR--RPDGSV
MAB_3148c|M.abscessus_ATCC_199 RAEH------PHRESGDDLRASFDERGVQYGPAFQGLAAAYRGDETVRSV
MAV_2370|M.avium_104 LTAH------PHDDDGDEVRRRMDRRGVQYGPAFAGLGAVHSGDETG-TV
MMAR_3797|M.marinum_M WPPE-----GAVAVPADSMYDRLATAGFHYGPAFQGVRAIWR---RDDEW
MSMEG_6767|M.smegmatis_MC2_155 TSTDG-----------DTFYQRTQALGFDYGEAFRSVASVTAG---RDWA
. * :
Mvan_3852|M.vanbaalenii_PYR-1 LLRVRAEADGSTPRS----WAGLLDAATSAASTVFDGP------PRLRMP
Mflv_2690|M.gilvum_PYR-GCK VLRVSAQEDGSAPAN----WAGLLDAATSAASTVFDGP------PRLRMP
TH_2454|M.thermoresistible__bu FARVAAEPDKSAPAT----WAGLIDAATSTASTIFDGP------PRLRMP
Mb2956|M.bovis_AF2122/97 TVAIDLPEALPEGS-----TGPLLDAAVHLAALSDVAD------SRLYVP
Rv2931|M.tuberculosis_H37Rv TVAIDLPEALPEGS-----TGPLLDAAVHLAALSDVAD------SRLYVP
MLBr_02357|M.leprae_Br4923 TVEIEFPDTLPDGA-----IAPLLDAAILIPALADVTE------TQFYVP
MUL_2016|M.ulcerans_Agy99 ETEITLSDEAPRHQGYR-IHPAMLDAALQSLAAAVPNDEFAGSAEASYLP
MAB_3148c|M.abscessus_ATCC_199 LAEVTLPRDVRAQQGSYIVHPALLDACFQSVIALPDVQEAS--KDALPLP
MAV_2370|M.avium_104 LAEVALPRQIRSQQAAYGAHPALLDACFQSVEAHPAVRALG--DGALGLV
MMAR_3797|M.marinum_M FAEIALDSDQIDEATDFGLHPALFDAALHVATELLGEQYPP---GQVPLP
MSMEG_6767|M.smegmatis_MC2_155 VAQIDIPQSISADVDTYRFHPALIDGAFQTLFGAPFSGQEE--NTDPYLP
: ::*.. :
Mvan_3852|M.vanbaalenii_PYR-1 ARIERVHVC-----GDPPAVALLHVRRR-QGTATDVAIADESGAVRASIT
Mflv_2690|M.gilvum_PYR-GCK AHIERVHVR-----ADPPAVALLHVRHR-GGTATDVTIADESGAVRAFIA
TH_2454|M.thermoresistible__bu ARIERVHVR-----DKPPAIALLHVRRRPEGTVTDVTIAEESGAVSVTLT
Mb2956|M.bovis_AF2122/97 ASIEQISLG-DVVTGPRSSVTLNRTAHDDDGITVDVTVAAHG-----EVP
Rv2931|M.tuberculosis_H37Rv ASIEQISLG-DVVTGPRSSVTLNRTAHDDDGITVDVTVAAHG-----EVP
MLBr_02357|M.leprae_Br4923 ASIKQVWLG-DTATGPCGAVTLNRTACDDDGITVDVTVADGS-----GVP
MUL_2016|M.ulcerans_Agy99 VSFETLRVYSNPGRHARCRAQLTNLNDGGAGKLGRITLTDDAGNVTVEIT
MAB_3148c|M.abscessus_ATCC_199 KGVRSLHAYESARATQYCYTRVTKVVGNEVEADIDLLDETGSVLIAVRGF
MAV_2370|M.avium_104 LGIRRLRAYGAARNAHYCYTRVTKADTSGVEADIDVLDEHGAVLLAVQGL
MMAR_3797|M.marinum_M FAWNGVRLP-------GRGASALRVALHPTDTGLRLHAVDQSGTPMLGVD
MSMEG_6767|M.smegmatis_MC2_155 TRIRHCAVYGPPAEHMTVRARVLSATHDAVECDITITDPSGGVLAAFDGF
. : .
Mvan_3852|M.vanbaalenii_PYR-1 AMTFEELESATG----ADPSRMLHHVAWHVTPFCADDR------------
Mflv_2690|M.gilvum_PYR-GCK GMTFDELESPAG----VDLSRMMHHVAWHDTCYDVEAR------------
TH_2454|M.thermoresistible__bu GMGFEELENPGGGGSSGDLTGMLHHLRWHPVDWPDTDP------------
Mb2956|M.bovis_AF2122/97 SLSMRSLRYRALDFGLDVGRAQPPASTGPVEAYCDATN----FVHTIDWQ
Rv2931|M.tuberculosis_H37Rv SLSMRSLRYRALDFGLDVGRAQPPASTGPVEAYCDATN----FVHTIDWQ
MLBr_02357|M.leprae_Br4923 LALMRSLRYRALDLDNAQQDYSTVFVESHVDALTDARN----FVHAIDWQ
MUL_2016|M.ulcerans_Agy99 DIYLRRVERRSVPLPLAQKIFDTEWVEKSIAGADQPDAP---GSWLVLTD
MAB_3148c|M.abscessus_ATCC_199 RFGTGSSDDEQRDQLLNNRLLAIEWQQQRLPESVSGAPRRWLLVSTGESV
MAV_2370|M.avium_104 RVGTSASESGTRDRVLTERLLNIEWRQRELPEPEHADAASWLLIGTTATA
MMAR_3797|M.marinum_M ALAVRPIDATQLARRATRREPLHVVGWTPIHTDEALPR------------
MSMEG_6767|M.smegmatis_MC2_155 TVQSLSASSRMSADHIDKGLFALEWSPVTDTPDTAHGD------------
Mvan_3852|M.vanbaalenii_PYR-1 ---PTEVAVIGGGV-DIDPVVRDLSDAGVPHRVYGSPGQVPGDTGERSVV
Mflv_2690|M.gilvum_PYR-GCK ---PVEVALVACG--DSAEMQRDLLAAGVPVDDHSTVDEVSDTLEPGAVV
TH_2454|M.thermoresistible__bu ---PAAVVLVGGDARTRAFVTRDLDEARVAHRSYADPAALPPDLTAGTVV
Mb2956|M.bovis_AF2122/97 PQTVPDATHPGAEQVTHPGPVAIIGDDGAALCETLEGAGYQPAVMSDGVS
Rv2931|M.tuberculosis_H37Rv PQTVPDATHPGAEQVTHPGPVAIIGDDGAALCETLEGAGYQPAVMSDGVS
MLBr_02357|M.leprae_Br4923 PRTDLDCSN---TPVASSGSVAVIGDARAGFGLLLKEAGYTLAAPADGVS
MUL_2016|M.ulcerans_Agy99 AKSNADEFVARWSSPQRRVITADLGDEAAMLAAFAETAGDPERLPVGVVV
MAB_3148c|M.abscessus_ATCC_199 DPWAAELIDSLKVRESEVSLIQWRPNTDRVAALKLLYDQLESGTFDGVLV
MAV_2370|M.avium_104 DVLASTLADTLKNHGAQCTTMAWPQQADHTAHAEQLRNQWRGDGFTGVVV
MMAR_3797|M.marinum_M ----QLALLEGNTAFDLGGIIAGEVGRYPSIAALVDEIRAGGAAPEIVLT
MSMEG_6767|M.smegmatis_MC2_155 ---ESTWLILTDNGGVGEAIADGLRLRGHHVHTVAHDPTGEIDWPDMLAT
Mvan_3852|M.vanbaalenii_PYR-1 LLLP-RDDSPEAAAEQVLDTLKHLCD-----------------NNSQARL
Mflv_2690|M.gilvum_PYR-GCK LLVPPVDAPPEASAELVLNSLKVLHA-----------------KGSEARL
TH_2454|M.thermoresistible__bu LVLPRTAARPAASAQLVLHTLQRLSA-----------------TNSGARL
Mb2956|M.bovis_AF2122/97 QARYVVYVADSDPAGADETDVDFAVR-ICTEITGLVRTLAERDADKPAAL
Rv2931|M.tuberculosis_H37Rv QARYVVYVADSDPAGADETDVDFAVR-ICTEITGLVRTLAERDADKPAAL
MLBr_02357|M.leprae_Br4923 EVRYVVYVADPHPATTAETDVDFAVR-ITAEISDLVRALAKREPGKPVAL
MUL_2016|M.ulcerans_Agy99 FVGGAGNNSGTADDGRISYDGLIQSRDTVWQISTVVRAIVGTWHGRAPRL
MAB_3148c|M.abscessus_ATCC_199 VTAPGSEGGADRVVLQGADQVRHLVR---------ITRELVDLPGEPPRL
MAV_2370|M.avium_104 LTGPKNGDNDQESALLSRDHVQHLVR---------IARELTDLPGEPPRL
MMAR_3797|M.marinum_M AAAVTTDDQSGALGKAARTGLYHTLG--------LVQAWLSQPELLDTRL
MSMEG_6767|M.smegmatis_MC2_155 HLSGERTGLIDCWPLEVTDAATDPAG---TATVLRIVKALATLDGVTPRL
*
Mvan_3852|M.vanbaalenii_PYR-1 WVLTNR----------VHEGGNLVHAPLWGMSRIAAAEHP-QLWGGVLDV
Mflv_2690|M.gilvum_PYR-GCK WVLTRR----------VHEGANLVHAPLWGLARVAAAEHP-HLWGGVLDV
TH_2454|M.thermoresistible__bu WVLTRG----------VHEGTDPGHGPLWGLARVAAAEHP-QLWGGLLDI
Mb2956|M.bovis_AF2122/97 WILTRG-------VHESVAPSALRQSFLWGLAGVIAAEHP-ELWGGLVDL
Rv2931|M.tuberculosis_H37Rv WILTRG-------VHESVAPSALRQSFLWGLAGVIAAEHP-ELWGGLVDL
MLBr_02357|M.leprae_Br4923 WIVTRG-------VYESVASSALRQSFLWGFGGVIAAEHP-EMWGGLVDL
MUL_2016|M.ulcerans_Agy99 WLVTEGG------LVVHDKPGRPAIGALQGLVRVLAYEHP-ELRATLVDL
MAB_3148c|M.abscessus_ATCC_199 FVVTRNAQ-----TVVDGDITNLEQAGLRGLVRVIGAEYP-HLRVTHIDV
MAV_2370|M.avium_104 YVVTRNAQ-----TVLPNDVPNLGQAGLRGLVRVIGMEHP-QLGAGQIDV
MMAR_3797|M.marinum_M VFVTQAAL-----TVSGDETPELAAAPIDGLLRSAACEHP-GRFAHIDVD
MSMEG_6767|M.smegmatis_MC2_155 YLVTANAQPAAGTELTGTELTGVEQAAFWGLGRVIGHQELGEYWGGLIDI
.:* . : *: . :
Mvan_3852|M.vanbaalenii_PYR-1 ACG--------------GVPLGVLASLHGHGVVVARDGVAMTARLSHAQS
Mflv_2690|M.gilvum_PYR-GCK ADG--------------PLPVGVLASMAGHGVVVFRDGRARTARLTPARP
TH_2454|M.thermoresistible__bu GED--------------RLPVRALTALTGHGVVVVRDGVAHTARLAPAGP
Mb2956|M.bovis_AF2122/97 AIN-------DDLGEFGPALAELLAKP-SKSILVRRDGVVLAPALAPVRG
Rv2931|M.tuberculosis_H37Rv AIN-------DDLGEFGPALAELLAKP-SKSILVRRDGVVLAPALAPVRG
MLBr_02357|M.leprae_Br4923 AASALGADRDDILDQFGPTLASLLQTP-TRSIVVLRDGVVLAPTLVPIRS
MUL_2016|M.ulcerans_Agy99 DTG------ADAVTRLAGELSSPRDDPNYDDVVAWRDGHRYVTQLCRAIL
MAB_3148c|M.abscessus_ATCC_199 DRH-----------TAAQNVAGELVSGSEEDETAWREDHWYRARLNLGPL
MAV_2370|M.avium_104 DES-----------TDAQALARQLLAGSEEDETAWRDGAWYTARLCPAPL
MMAR_3797|M.marinum_M DSP------------ASRQALAAALSLRQEPRLAIRGGAVLAPRLAQVPA
MSMEG_6767|M.smegmatis_MC2_155 DHADAP-------SSTAEQICGHVLGDGAEDQIALRGNQILAPRLRPCSG
. * . . *
Mvan_3852|M.vanbaalenii_PYR-1 GG------------------------------------------------
Mflv_2690|M.gilvum_PYR-GCK AG------------------------------------------------
TH_2454|M.thermoresistible__bu GARD----------------------------------------------
Mb2956|M.bovis_AF2122/97 EP------------------------------------------------
Rv2931|M.tuberculosis_H37Rv EP------------------------------------------------
MLBr_02357|M.leprae_Br4923 EP------------------------------------------------
MUL_2016|M.ulcerans_Agy99 DPE-----------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 GPDDWRSTVATPNNEGVRFEVRTPGDLQSLGFVAFDRVAPGPGQIEVSVT
MAV_2370|M.avium_104 LPEERHTAVANHECDGMRLQIRTPGDLESLELVACDRIPPGPGQIEVAVS
MMAR_3797|M.marinum_M HSPK----------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 LTKP----------------------------------------------
Mvan_3852|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2690|M.gilvum_PYR-GCK --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
Mb2956|M.bovis_AF2122/97 --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 ATSINFADVLNVYGRYSSFEGRQ-ELGVDFAGVVTAVGEGVTQHQVGDRV
MAV_2370|M.avium_104 ASSINFADVLVAFGRYPAFEGRLPELGTDFAGVVTAVGPDVTDHKVGDHV
MMAR_3797|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3852|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2690|M.gilvum_PYR-GCK --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
Mb2956|M.bovis_AF2122/97 --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 GGMTPTGAWRSFVVVDANLAATLPAEVPDREAAAVPGAHVTAWYGLHELA
MAV_2370|M.avium_104 GGLSANGCWGTFLTCDARLAVTLPPGLADDQAAAVTTAHATAYYGLHELA
MMAR_3797|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3852|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2690|M.gilvum_PYR-GCK --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
Mb2956|M.bovis_AF2122/97 --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 RISAGDKVLIHSGTGGVGQAAIAIARAAGAEIYATAGSPERRDLLRSWGI
MAV_2370|M.avium_104 RIGAGDRVLIHSATGGVGQAAIAIARAAGAEIFATAGSEQRRQLLRDMGI
MMAR_3797|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3852|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2690|M.gilvum_PYR-GCK --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
Mb2956|M.bovis_AF2122/97 --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 KHVYDSRSTDFAELIRRDTDGYGVDIVLNSLTGAAQRAGVELLTFGGRFI
MAV_2370|M.avium_104 EHVYDSRTVEFADLIRHDTDGYGVDIVLNSVTGAAQRAGIELLAFGGRFV
MMAR_3797|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3852|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2690|M.gilvum_PYR-GCK --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
Mb2956|M.bovis_AF2122/97 --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 EIGKRDIYGDTRLGLFPFRRNLSFHAVDLVLVAKTRPEAIYRTLTALYGQ
MAV_2370|M.avium_104 EIGKRDIYGDTRLGLLPFRRNLTFYALDLALMSFSHPDRLRGLLRTVYRL
MMAR_3797|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3852|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2690|M.gilvum_PYR-GCK --------------------------------------------------
TH_2454|M.thermoresistible__bu -------------------------------------------------S
Mb2956|M.bovis_AF2122/97 --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199 MAEGVLPLPEISPSPLQEAAESIRVMGAAGHTGKLVLDLPKAGEVSAVIP
MAV_2370|M.avium_104 TADGALPMPESTHYPLADAASAIRVMSAAQHTGKLVLDVPHAGRSRVVVP
MMAR_3797|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3852|M.vanbaalenii_PYR-1 -GAPMTCTPGGTYLVTGGTGALGLRIAQRLADLG----ARRLVLLSRSGL
Mflv_2690|M.gilvum_PYR-GCK -GDAMTCTPGGTYLITGGTGALGLRIAQRLADLG----ARRLVLLSRSGV
TH_2454|M.thermoresistible__bu AGEGLRCSPGGTYLITGGTGALGLRLAHRLADLG----ARRLVLVSRSGM
Mb2956|M.bovis_AF2122/97 ARKSLQCRPDAAYLITGGLGALGLLMADWLADRG----AHRLVLTGRTPL
Rv2931|M.tuberculosis_H37Rv ARKSLQCRPDAAYLITGGLGALGLLMADWLADRG----AHRLVLTGRTPL
MLBr_02357|M.leprae_Br4923 VRKSLQCKSDGAYLITGGMGALGLLMADWLADRG----ARRLVLMGRTPL
MUL_2016|M.ulcerans_Agy99 PQRDPVIRPGASYIVTGGLGGLGLVVARWLVDSG----AGRVVLNGRSEP
MAB_3148c|M.abscessus_ATCC_199 PSHAPAFRRDGAYVVTGGLGGLGLFLARKLAAAG----VGRIILNGRSAP
MAV_2370|M.avium_104 PAQVRAFRSDGAYIVTGGLGGLGLFLAEKMASPGSRAGCGRIVLCSRALP
MMAR_3797|M.marinum_M PVAAPVFDPQATVLITGGTGVLGMALARHLATHHH---CEHLLLVSRRGV
MSMEG_6767|M.smegmatis_MC2_155 --FPTKLTADATYVVTGGAGALGRVVATYLAERG----ARHITLLGRSPI
.: ::*** * ** :* :. :: * .*
Mvan_3852|M.vanbaalenii_PYR-1 PHRDQWTDN-----QSEAVRAVAALEERGVSVHVAAIDIGAAGAGDQLRA
Mflv_2690|M.gilvum_PYR-GCK PHRSRWADSG----DNDAVRAVTALEERGVTVHIAAVDIGAPGADDQLRT
TH_2454|M.thermoresistible__bu PARDSWGRAG----DSDTVAAITALEERGVSVRVAALDIGAPGAAARLRE
Mb2956|M.bovis_AF2122/97 PPRRDWQLDTLDTELRRRIDAIRALEMRGVTVEAVAADVGCREDVQALLA
Rv2931|M.tuberculosis_H37Rv PPRRDWQLDTLDTELRRRIDAIRALEMRGVTVEAVAADVGCREDVQALLA
MLBr_02357|M.leprae_Br4923 PPRRDWELDTLDAGLRQKIDAICALEMRGVTVEAVAVDVGHHDDVQALLA
MUL_2016|M.ulcerans_Agy99 SD--------------EQRKVLAELESR-AEVVVVCGDSATEGVAESLVA
MAB_3148c|M.abscessus_ATCC_199 KP--------------EALAAIEQIRQGGTEIDVALGDIAEPDTAQRLVA
MAV_2370|M.avium_104 NP--------------KALATLERIRQMGADIVVERGDIAEAGTAQRLLD
MMAR_3797|M.marinum_M AADG-------------AQELRAELAGHGCQVEFAACDTADSDQLSTLLQ
MSMEG_6767|M.smegmatis_MC2_155 SPRDRWASITEDDAHHATVDAIRAIERLGAHVSTASVDITDSDQVRAWLR
: : *
Mvan_3852|M.vanbaalenii_PYR-1 MLR--ELPPVRGVVHAAGVEAGALLLDTSADDIRA-AMRPKVAGTLILH-
Mflv_2690|M.gilvum_PYR-GCK ILR--ELPAVRGVVHAAGVEAGALLLTTSAADLHA-AMRPKVAGTLTLH-
TH_2454|M.thermoresistible__bu VLA--DLPDVRGVIHAAGVEAGALLTNTTAEDIEA-TMRPKVDGVLALH-
Mb2956|M.bovis_AF2122/97 ARDRDGAAPIRGIIHAAGITNDQLVTSMTGDAVRQ-VMWPKIGGSQVLH-
Rv2931|M.tuberculosis_H37Rv ARDRDGAAPIRGIIHAAGITNDQLVTSMTGDAVRQ-VMWPKIGGSQVLH-
MLBr_02357|M.leprae_Br4923 KRDRDGAAPIRGIIHAAGVTNDQLVTNMTDDPVRQ-VMWPKIAGCQVLH-
MUL_2016|M.ulcerans_Agy99 AAE-DQQRQLRGIVHGAAVIDDSLLFSMTKDSLER-VWAPKAAGALRLH-
MAB_3148c|M.abscessus_ATCC_199 AAT-ETGKPVRGVLHAAALVHDATLANITDELIDRGDWRPKVHGAWNLH-
MAV_2370|M.avium_104 VAT-ATGLPVRGVLHLAAVIEDATLANITDELIER-DWAAKVYGAWNLHC
MMAR_3797|M.marinum_M SIP--VEHPLGAVIHAAGVLSDGVIEGLGREQVEQ-VLRPKLDAALLLH-
MSMEG_6767|M.smegmatis_MC2_155 EHTGSGGRPVRGIVHAAGSVRDQLLVNMGEDDFAE-VLAPKITGTRVLHN
: .::* *. . : . .* . **
Mvan_3852|M.vanbaalenii_PYR-1 ---ELFPPEQLDWMVLFSSCGYLAGFPGQGAYACANAFLDATARHRCALG
Mflv_2690|M.gilvum_PYR-GCK ---ELFPPGQLDWMVLFSSCGYLAGFPGQGAYACANAFLDAAARHRRSLG
TH_2454|M.thermoresistible__bu ---EVFPPGRLDWLVLFSSCGYLGGFPGQGAYACGNAYLDAFARYRRASG
Mb2956|M.bovis_AF2122/97 ---DAFPPGSVDFFYLTASAAGIFGIPGQGSYAAANSYLDALARARRQQG
Rv2931|M.tuberculosis_H37Rv ---DAFPPGSVDFFYLTASAAGIFGIPGQGSYAAANSYLDALARARRQQG
MLBr_02357|M.leprae_Br4923 ---EAFPPGSVDFFYLTSSAAGIFGIPGQGSYAAANSYLDALARTRRQQG
MUL_2016|M.ulcerans_Agy99 ---DATATRELDWWLGFSSTASLLGSPGQTAYACASAWLDGLVAWRRAAG
MAB_3148c|M.abscessus_ATCC_199 ---EATADQPLDWFCSFSSIAALVGSPGQGAYAAANSWLDGFTHWRRAQG
MAV_2370|M.avium_104 ALQESGAEQSLDWFCSFSSAAALVGSPGQGAYAAANSWLDAFTRWRRARG
MMAR_3797|M.marinum_M ---ELTQDLDLSAFVLFSSAAGVLGSPGQANYAAANAFLDALAQYRRRHG
MSMEG_6767|M.smegmatis_MC2_155 ----VFEDHDLEFFVMFGSAGSTIAAPGQGNYAAANAFLDAFAHHRQGLG
:. .* . . *** **...::**. . * *
Mvan_3852|M.vanbaalenii_PYR-1 DRTVSVAWTAWRGLG------------------MGSTSGFVAAQLEALGM
Mflv_2690|M.gilvum_PYR-GCK DRTVSIAWTAWRGLG------------------MGSTSGFVAAQLEALGM
TH_2454|M.thermoresistible__bu DATTSVAWTAWRGLG------------------MGSASDFVAAQLDALGM
Mb2956|M.bovis_AF2122/97 CHTMSLDWVAWRGL------------------GLAADAQLVSEELARMGS
Rv2931|M.tuberculosis_H37Rv CHTMSLDWVAWRGL------------------GLAADAQLVSEELARMGS
MLBr_02357|M.leprae_Br4923 CHTMSIDWVAWRGL------------------GFAANAQIVSDELQRMGS
MUL_2016|M.ulcerans_Agy99 LPAATINWGPWSEVGVAQALVGTPLDPITPAEGLVALDALLAADRGRTGV
MAB_3148c|M.abscessus_ATCC_199 LPATVIAWGAWSEIG-------------------------QGTHLAQNAE
MAV_2370|M.avium_104 LKATAIAWGAWAQIG-------------------------RGAALADSAD
MMAR_3797|M.marinum_M LAAVSLAWGLWGQASG----------------LTGQLDQTDYARMRRMGL
MSMEG_6767|M.smegmatis_MC2_155 LPALTIGWGPWSVG--------------------MVEELGLEKVYAQRGI
: : * * .
Mvan_3852|M.vanbaalenii_PYR-1 GTVGADDAMRALDTAMRGEEPNVVVLPVLPGAAAVPMLSDVAPTGRDDDD
Mflv_2690|M.gilvum_PYR-GCK GTVGADDAFRALDSAMRGQDPNVVVLPVLPEASAVPMLAEVAPTDQSDGG
TH_2454|M.thermoresistible__bu GTVDVDDAMRALDAAIRDGDPNVVVLPLSPAAAAVPMFADVAPADPDADA
Mb2956|M.bovis_AF2122/97 RDITPSEAFTAWEFVDGYDVAQAVVVPMPAPAGADGSGA-NAYLLPARNW
Rv2931|M.tuberculosis_H37Rv RDITPSEAFTAWEFVDGYDVAQAVVVPMPAPAGADGSGA-NAYLLPARNW
MLBr_02357|M.leprae_Br4923 RDITPSEAFTAWEYVDAYDVAQAVVLPVPRSYGSAGSTAGDSYLVPARNW
MUL_2016|M.ulcerans_Agy99 ARLRSDRALIAFPEIRNLGYFTLVVQELDAAGDGGDWAG-------PEAL
MAB_3148c|M.abscessus_ATCC_199 AAILPDEGAYAFDTVLRHNRAYTAYAPMAGISWLADFVERSPFAQAFRDA
MAV_2370|M.avium_104 VAITPDEGAYAFEALLRHDRACTGYAPITGTPWLTAFAQRSPFAEAFRAN
MMAR_3797|M.marinum_M AAMATDEGLQLFDLACGRPEPVLVPALLDTNALRAQAHAGILPPLFSGLI
MSMEG_6767|M.smegmatis_MC2_155 ELITPAVGARIIDRLLSQSVPAVVAMNADWSRARQVGFGGLVPKMFGELG
: .
Mvan_3852|M.vanbaalenii_PYR-1 ---VAPVG-------------PGDADLDEWVAREVAAAVAAELGLPES-E
Mflv_2690|M.gilvum_PYR-GCK ---DVAAG-------------PGDADLGEWVAQQVIEAVAAELGLSET-D
TH_2454|M.thermoresistible__bu PGGEVPDGLSD---GFPADGFPDDGDLAEWVHRRVIAAVAGELGLAET-D
Mb2956|M.bovis_AF2122/97 S-------------------VMAATEVRSELEQGLRRIIAAELRVPEK-E
Rv2931|M.tuberculosis_H37Rv S-------------------VMAATEVRSELEQGLRRIIAAELRVPEK-E
MLBr_02357|M.leprae_Br4923 S-------------------QMEAAEVRKELESGLRTIIAAELRVAEA-E
MUL_2016|M.ulcerans_Agy99 K-------------------EMDPAEARQVVTERLHTRIAAVMGYADRSA
MAB_3148c|M.abscessus_ATCC_199 GQNQTETN---------KFLDELRALPREEWPTRLRKLVAEQVGLVLRRS
MAV_2370|M.avium_104 GQSATGTS---------KLRAELEELPPEEWSTRLRRLISDQVSLILRRN
MMAR_3797|M.marinum_M RMPAKRARAAA--TLAQRLTEIPQSEWDALLLSEVRSHVATALNYSGPEA
MSMEG_6767|M.smegmatis_MC2_155 TADTVGGQDGVGPSILELLAHTADADRPAVIAEQVRRLVAAVFDCAVT-D
: :: .
Mvan_3852|M.vanbaalenii_PYR-1 VDPRVPLVEAGVDSIMTVALRRALEKRTGLALPPTLLWEHPTAAAVTDRI
Mflv_2690|M.gilvum_PYR-GCK VDPRVPLVETGVDSIMTVALRRTLEKRTGLALPPTLLWEHPTAAAVSDRI
TH_2454|M.thermoresistible__bu VDPRLPLVEIGVDSIMTVALRRQLERQTGLTLPPTLLWEHPTAGAVSDRI
Mb2956|M.bovis_AF2122/97 LDTDRPFAELGLNSLMAMAIRREAEQFVGIELSATMLFNHPTVKSLASYL
Rv2931|M.tuberculosis_H37Rv LDTDRPFAELGLNSLMAMAIRREAEQFVGIELSATMLFNHPTVKSLASYL
MLBr_02357|M.leprae_Br4923 LDTDRPFAELGLNSLMAMAIRREAEQFIGIELSAIMLFNHPTVALLAAYL
MUL_2016|M.ulcerans_Agy99 VDASMPLTELGLDSLMAVRIRNTARADFGVEPPVTLILQGASLHDLTVDV
MAB_3148c|M.abscessus_ATCC_199 IDPDRSLPDYGLDSLGNLEIRTRIQADTGVRIGPADVS---TVRSLAAHI
MAV_2370|M.avium_104 VDPDRPLPEYGLDSLGGLELLTRIQTETGIRVSPADIAAIGTIRGLADLL
MMAR_3797|M.marinum_M IDPIQAFNEIGLDSLGAIELRNRLTQTTGLKLPTTLIFDHPNPTALAHYL
MSMEG_6767|M.smegmatis_MC2_155 IEPDDMLDDIGLDSMMAMDFRVRINSAFSIDLPVLEILRGVSVNSLSARI
::. : : *::*: : : .: : . :: :
Mvan_3852|M.vanbaalenii_PYR-1 VELLTPHPEKADIS------------------------------------
Mflv_2690|M.gilvum_PYR-GCK VELLAPQSEKTGVT------------------------------------
TH_2454|M.thermoresistible__bu VEMLRARG------------------------------------------
Mb2956|M.bovis_AF2122/97 AKRVAPHDVSQDNQISA-LSSSAGSVLDSLFDRIESAPPEAERSV-----
Rv2931|M.tuberculosis_H37Rv AKRVAPHDVSQDNQISA-LSSSAGSVLDSLFDRIESAPPEAERSV-----
MLBr_02357|M.leprae_Br4923 TKVVAPQHDSQGDEMAA-LSASAGGVLDSLFDRIESTSTEAEGLV-----
MUL_2016|M.ulcerans_Agy99 IRQLDLAGDEQTHEHVD-VVRDR--AQQRAAARHGAAMRRKRG-------
MAB_3148c|M.abscessus_ATCC_199 YDRLAEQESEVASS------------------------------------
MAV_2370|M.avium_104 RDKLTPAGAAQAERV-----------------------------------
MMAR_3797|M.marinum_M RTQFTETTTCESVHSLN-EEIAKVESLLAAVAMDKKMASQVEDRLRLLSA
MSMEG_6767|M.smegmatis_MC2_155 LAELRDIHGVAPVEPDTGETASEPTTTDDDVERLLQDLSEAEMRQLLAEL
.
Mvan_3852|M.vanbaalenii_PYR-1 ----------------------------------------
Mflv_2690|M.gilvum_PYR-GCK ----------------------------------------
TH_2454|M.thermoresistible__bu ----------------------------------------
Mb2956|M.bovis_AF2122/97 ----------------------------------------
Rv2931|M.tuberculosis_H37Rv ----------------------------------------
MLBr_02357|M.leprae_Br4923 ----------------------------------------
MUL_2016|M.ulcerans_Agy99 ----------------------------------------
MAB_3148c|M.abscessus_ATCC_199 ----------------------------------------
MAV_2370|M.avium_104 ----------------------------------------
MMAR_3797|M.marinum_M TLHDFLAGIPADISDIDNDLQFESDDELFDILDDEFGANN
MSMEG_6767|M.smegmatis_MC2_155 EASGTEAGGAIS----------------------------