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PMPNTDHTSRQPLAIVGIGCRFPGGADSAQRYWDLLCNNIDATREVPENRWNAAKYHDPNPAKIGKIVTR RGGFLDQIDQFDPQFFGISPREAHSLDPQQRLLLQATWEALEDGGIPADELAGTDVGVFVGGFTLDYQLL QNQGRTSRYRFKPHSATGMMMTMLANRISHAFDFRGPSMAIDTACSSSLVAVHLAAQSIWDGDCDVALAG GVNIMVGPNTAIAESKSGFLSPEGRSKAFSDTADGYARGEGGAVVVIKPLAHALRDGDDIYAQILGTAVS QDGHTDGITVPNEEAQEAAIRMALQRAGVEPNDVAYVEAHGTGTPVGDPIEMRALAGALTTDRDATRPLV IGSVKTNIGHLEAGAGVAGLIKAALIVKHGHIPANLHLKNPTRHVSLTELKLDIPTIGRPFPECDRRIAG INSFGFGGTNAHVVLAEPPAARHSAETGDHRVLTVLPISARSEEALVATAGRLAGHLAAHPEVTLADLGY TLSHRRAHLNHRHTFVVDSIDEARRQLQAVADGGQISAGRAGEARLAFVCTGMGPQWWQMCRGLLDVFPV FTDSIHRTDRELSRYADWSLLEELTRDEASSRMGETEFAQPANFAIQVALAEQLAHFGITPDAVIGHSAG EVAAHHIAGLLTFEQAVHVIYHRSRLQQRTTGQGRMLAVGLDAETLMQILDEKILDQFGRRVSVAAINSP SAVTVAGDADVLEDIARHLDEAQIFNRYLAVKVPYHTHYMETIKDDLHTAFASLSSKAATLPLYSTVTGE LLDRYDAGAAYWWQNTRATVLFEPAMRRMLDDGYTHFVELGPHPVLAASILESAGTQRVSVDASQRRGQD DARTLLNCVGALHSRGHEVAWDMVQPRAGAHPVKLPSYPWQTKRFWNDTHEAEEALFYRPVHPLLGQPVR AVHPTWEAEFSTLTVPFLADHQVQGSVVVPGAVYVEMALAAGRETYGSDLSVDNLVLHRAVILDDTCDPV IRTTVDQDDGSVEFAALIATADTDLKWVITATAELNTLPRAPRAGDTGGGAVTSTDGDTFYQRTQALGFD YGEAFRSVASVTAGRDWAVAQIDIPQSISADVDTYRFHPALIDGAFQTLFGAPFSGQEENTDPYLPTRIR HCAVYGPPAEHMTVRARVLSATHDAVECDITITDPSGGVLAAFDGFTVQSLSASSRMSADHIDKGLFALE WSPVTDTPDTAHGDESTWLILTDNGGVGEAIADGLRLRGHHVHTVAHDPTGEIDWPDMLATHLSGERTGL IDCWPLEVTDAATDPAGTATVLRIVKALATLDGVTPRLYLVTANAQPAAGTELTGTELTGVEQAAFWGLG RVIGHQELGEYWGGLIDIDHADAPSSTAEQICGHVLGDGAEDQIALRGNQILAPRLRPCSGLTKPFPTKL TADATYVVTGGAGALGRVVATYLAERGARHITLLGRSPISPRDRWASITEDDAHHATVDAIRAIERLGAH VSTASVDITDSDQVRAWLREHTGSGGRPVRGIVHAAGSVRDQLLVNMGEDDFAEVLAPKITGTRVLHNVF EDHDLEFFVMFGSAGSTIAAPGQGNYAAANAFLDAFAHHRQGLGLPALTIGWGPWSVGMVEELGLEKVYA QRGIELITPAVGARIIDRLLSQSVPAVVAMNADWSRARQVGFGGLVPKMFGELGTADTVGGQDGVGPSIL ELLAHTADADRPAVIAEQVRRLVAAVFDCAVTDIEPDDMLDDIGLDSMMAMDFRVRINSAFSIDLPVLEI LRGVSVNSLSARILAELRDIHGVAPVEPDTGETASEPTTTDDDVERLLQDLSEAEMRQLLAELEASGTEA GGAIS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6767 | - | - | 100% (1826) | mycocerosic acid synthase |
| M. smegmatis MC2 155 | MSMEG_0408 | - | 0.0 | 33.45% (1441) | type I modular polyketide synthase |
| M. smegmatis MC2 155 | MSMEG_4727 | - | 0.0 | 33.52% (1429) | mycocerosic acid synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2959 | ppsD | 0.0 | 33.12% (1836) | phenolpthiocerol synthesis type-I polyketide synthase PPSD |
| M. gilvum PYR-GCK | Mflv_3395 | - | 0.0 | 31.60% (1826) | acyl transferase domain-containing protein |
| M. tuberculosis H37Rv | Rv2934 | ppsD | 0.0 | 33.12% (1836) | phenolpthiocerol synthesis type-I polyketide synthase PPSD |
| M. leprae Br4923 | MLBr_02357 | - | 0.0 | 31.45% (1879) | polyketide synthase |
| M. abscessus ATCC 19977 | MAB_2212 | - | 0.0 | 37.81% (1407) | polyketide synthase |
| M. marinum M | MMAR_3799 | - | 0.0 | 31.55% (1867) | type I modular polyketide synthase |
| M. avium 104 | MAV_2370 | - | 0.0 | 33.89% (1428) | mycocerosic acid synthase |
| M. thermoresistible (build 8) | TH_2454 | - | 0.0 | 32.37% (1838) | PUTATIVE beta-ketoacyl synthase |
| M. ulcerans Agy99 | MUL_2016 | ppsD | 0.0 | 32.22% (1825) | phenolpthiocerol synthesis type-I polyketide synthase PpsD |
| M. vanbaalenii PYR-1 | Mvan_3124 | - | 0.0 | 31.50% (1832) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2959|M.bovis_AF2122/97 --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK MTSAFD-EDAIRNWLVDYLVTNIGCSPDEIDFDAPLNDLAVGSSDAVVLT
MLBr_02357|M.leprae_Br4923 MTASIGSEADLCHWLVNYLVTNIGCTPDEVDLNLSLTDLGMSSRDAVVLS
TH_2454|M.thermoresistible__bu --------------------------------------------------
MMAR_3799|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 ----------------------------------------MPMPNTDHTS
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2959|M.bovis_AF2122/97 ----------------MTSLAERAAQLSPNARAALARELVRAGTTFPTDI
Rv2934|M.tuberculosis_H37Rv ----------------MTSLAERAAQLSPNARAALARELVRAGTTFPTDI
MUL_2016|M.ulcerans_Agy99 ----------------MTSLAERAAQMSPKAREVLAHELVRAGTAFPTDI
Mvan_3124|M.vanbaalenii_PYR-1 ----------------MKTTFDRISAMSAEQRGKLAEQFEKASRVAG---
MAV_2370|M.avium_104 --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK GELSELLGRTVSPVEFWQYPTINALARFLTGGEVEAVAEVSPIRRVS---
MLBr_02357|M.leprae_Br4923 GELTDLLGKTVSPIDFWEHPTINALAAYLIAPAPDPESESAPRRSVQGAL
TH_2454|M.thermoresistible__bu -------------------------------MSVDVTAKARP--------
MMAR_3799|M.marinum_M -----------------MTTELDRATEGLRTAIAQIELLKLQNHALLAQA
MSMEG_6767|M.smegmatis_MC2_155 RQPLAIVGIGCRFPGG---ADSAQRYWDLLCNNIDATREVPENR-WNAAK
MAB_2212|M.abscessus_ATCC_1997 MVAVAIIGIGCRFPGG---IGDADSFWNFVLHKGDAVADIPKDR-WDADK
Mb2959|M.bovis_AF2122/97 CEPVAVVGIGCRFPGN---VTGPESFWQLLADGVDTIEQVPPDR-WDADA
Rv2934|M.tuberculosis_H37Rv CEPVAVVGIGCRFPGN---VTGPESFWQLLADGVDTIEQVPPDR-WDADA
MUL_2016|M.ulcerans_Agy99 AEPVAVVGIGCRLPGN---VSGPDSFWQLLVDGRDAVDEVPADR-WDADA
Mvan_3124|M.vanbaalenii_PYR-1 AEPIAVVGIGCRLPGG---VTGPDSYWELLENGTDAITEVPADR-WDGDA
MAV_2370|M.avium_104 MVPVAVIGMACRLPGA---VDSPERLWEALLRGDDFVTEIPPDR-WDADE
Mflv_3395|M.gilvum_PYR-GCK DDAIAVVGLGVRFPGGGDDIHGPDDLWEFLAQGRSAVSQVPPTR-WSWYD
MLBr_02357|M.leprae_Br4923 EEPIAVIGMGCRFPGG---ISGPEALWQFLCDRRSSIGQVPNER-WELFD
TH_2454|M.thermoresistible__bu DDPIAIIGIGCRLAGR---ITSPEEFWGFLLAGGSNVREIPAER-WEPYL
MMAR_3799|M.marinum_M NEPIAVVGMACRLPGG---IDSPETLWDVVTSEADTTSDFPTDRGWDLAE
.:*::*:. *:.* ..: * : . :.* * *.
MSMEG_6767|M.smegmatis_MC2_155 YHDPNPAKIGKIVTRRGGFLDQID-QFDPQFFGISPREAHSLDPQQRLLL
MAB_2212|M.abscessus_ATCC_1997 YYDPDPDTPGRMYTRRGSFLTQEFRRFDADFFGISHREAAVLDPQQRLLL
Mb2959|M.bovis_AF2122/97 FYDPDPSASGRMTTKWGGFVSDVD-AFDADFFGITPREAVAMDPQHRILL
Rv2934|M.tuberculosis_H37Rv FYDPDPSASGRMTTKWGGFVSDVD-AFDADFFGITPREAVAMDPQHRMLL
MUL_2016|M.ulcerans_Agy99 FYDPDPRAPGRMTTKWGGFIDDVA-GFDADFFGITPREAVAMDPQQRVLL
Mvan_3124|M.vanbaalenii_PYR-1 FYDPDPMAPGRMPTKWGAYLDDVS-GFDADFFGITPREAAAMDPQQRVLL
MAV_2370|M.avium_104 YYDPEPGVPGRSVSRWGAFIDDVA-GFDPEFFGINEREATAMDPQHRLLL
Mflv_3395|M.gilvum_PYR-GCK DGSPEGAAALAHTTRWGSYLSEID-EFDADYFEISPSEADKMDPQQRLLL
MLBr_02357|M.leprae_Br4923 DGSPEVKALLARTTRWGSFLEDID-AFDSEFFEISPSEADKMDPQQRLLL
TH_2454|M.thermoresistible__bu RRDPRNAAVLREITPWGTFLDDLA-GFDAEFFGVSPREAELTDPQQRLAL
MMAR_3799|M.marinum_M LFDPDPDTPGKTYSRTGGFLANIA-EFDAEFFGISAREAAAMDPQQRVLL
.* : * :: : **.::* :. ** ***:*: *
MSMEG_6767|M.smegmatis_MC2_155 QATWEALEDGGIPADELAGTDVGVFVGGFTLDYQLLQNQGRTSRYRFKPH
MAB_2212|M.abscessus_ATCC_1997 ETTWEALDDAGIAGQAVGG-NVGTFIGGFMNDNMISRGLARN-LEKINNF
Mb2959|M.bovis_AF2122/97 EVAWEALEHAGIPPDSLSGTRTGVMMGLSSWDYTIVNIERRA---DIDAY
Rv2934|M.tuberculosis_H37Rv EVAWEALEHAGIPPDSLSGTRTGVMMGLSSWDYTIVNIERRA---DIDAY
MUL_2016|M.ulcerans_Agy99 EVAWEALEHAGLPPDSLSGTRTAAVMGLSAWDYTIVNLERRA---EIDAY
Mvan_3124|M.vanbaalenii_PYR-1 EVAWEALENAGLAPDTLSETRTAVMMGVYYTEYQNSSAGNPD---TIDAY
MAV_2370|M.avium_104 ETSWEAMEHAGLTEERVADSRTGVFIGLTHGDYQLLAADTRS---VEGAY
Mflv_3395|M.gilvum_PYR-GCK EVTHEALEHAGIRPDVLRHTQTGVFVGACLGEYAVMASKDLA---EVNAY
MLBr_02357|M.leprae_Br4923 EVAWEALEHAGISSNSLRRSQTGVFAGSCLSEYGAIASTDLS---QVDGW
TH_2454|M.thermoresistible__bu EVSWEALEHAGVPPRSLAGTDTAVLMGVNSDDYGRLLMEDLP---GIEAW
MMAR_3799|M.marinum_M EVCWEALENASIDPTSLEGSNTGVFVGAYAQYYGDSDSDSSAG------L
:. **::...: : .... *
MSMEG_6767|M.smegmatis_MC2_155 SATGMMMTMLANRISHAFDFRGPSMAIDTACSSSLVAVHLAAQSIWDGDC
MAB_2212|M.abscessus_ATCC_1997 AAFSASQTLLSNRIAHALDLWGPSMTVDTACSSSLVTTHLAVRAVANGEC
Mb2959|M.bovis_AF2122/97 LSTGTPHCAAVGRIAYLLGLRGPAVAVDTACSSSLVAIHLACQSLRLRET
Rv2934|M.tuberculosis_H37Rv LSTGTPHCAAVGRIAYLLGLRGPAVAVDTACSSSLVAIHLACQSLRLRET
MUL_2016|M.ulcerans_Agy99 ISTGNPHSAAVGRISYLLGLRGPAVAVDTACSSSLVALHLACQSLRLRES
Mvan_3124|M.vanbaalenii_PYR-1 SATGNAHSVTVGRIAYLLGLKGPAVAVDTACSSSLVSIHLACHSLRMRES
MAV_2370|M.avium_104 GFSGSNFSLASGRIAYALGVHGPALTVDTACSSGLTAIHLACRSLHEGES
Mflv_3395|M.gilvum_PYR-GCK SGTGGALSIIANRVSYFYDLRGPSVTIDTACSSSLVAIHLACQSLRSGDS
MLBr_02357|M.leprae_Br4923 SNTGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAIHLACQSLRTADA
TH_2454|M.thermoresistible__bu TGIGTSLCGIANRVSHLLDLRGPSVALDAACAASLVAVHNACQLLRAGET
MMAR_3799|M.marinum_M VMTGAATSVVSGRVAYAFGLQGPAVTVDTACSSSLVAIHQACQSLRGGEC
. .*::: .. **::::*:**::.*.: * * : : :
MSMEG_6767|M.smegmatis_MC2_155 DVALAGGVNIMVGPNTAIAESKSGFLSPEGRSKAFSDTADGYARGEGGAV
MAB_2212|M.abscessus_ATCC_1997 DVALAGGVNVMFQPETFITMCKGRFLAADGRSKSFDAAADGYGRGEGVGI
Mb2959|M.bovis_AF2122/97 DVALAGGVQLTLSPFTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGV
Rv2934|M.tuberculosis_H37Rv DVALAGGVQLTLSPFTAIALSKWSALSPTGRCNSFDANADGFVRGEGCGV
MUL_2016|M.ulcerans_Agy99 DVALAGGVQLMLSPFTSIALSKWSALSPTGRCKTFDALADGFVRSEGCGV
Mvan_3124|M.vanbaalenii_PYR-1 DLALAGGVSLNLRPETQLALAKWGMLSPHGKCFAFDSRADGFVRGEGAGV
MAV_2370|M.avium_104 DLALAGGATLALDPRKFSAGSAEGMLSPTGRCHAFDVAADGFVGGEGSVM
Mflv_3395|M.gilvum_PYR-GCK DVALAGGVNVILSPAVTRSFDQAEAMSKSGRCHAFDSRADGFVRGEGCGV
MLBr_02357|M.leprae_Br4923 NLAIAAGVNLLLSPAVFRGFDQVGALSPTGCCRAFDAAADGFVRGEGAGV
TH_2454|M.thermoresistible__bu GLAIAGGVSALIGPGLTRVLDKAGATAPDGRCKSFDASADGYGRGEGAAV
MMAR_3799|M.marinum_M SMALAGGVTAMATPRIFTEFSRQRGLAPDGRCKSFAAAADGTVLAEGAGV
.:*:*.*. * : * . :* *** .** :
MSMEG_6767|M.smegmatis_MC2_155 VVIKPLAHALRDGDDIYAQILGTAVSQDGHTDGITVPNEEAQEAAIRMAL
MAB_2212|M.abscessus_ATCC_1997 VVLKNLEQAQRDGDHIYAVIRGSGVNQDGRTIALPVPNPVSQQRLADRVI
Mb2959|M.bovis_AF2122/97 VVLKRLADAVRDQDRVLAVVRGSATNSDGRSNGMTAPNALAQRDVITSAL
Rv2934|M.tuberculosis_H37Rv VVLKRLADAVRDQDRVLAVVRGSATNSDGRSNGMTAPNALAQRDVITSAL
MUL_2016|M.ulcerans_Agy99 VVLKRLVDAVRDGDRVLAVVRGSAINQDGRSNGMTAPNAAAQRDVIGTAL
Mvan_3124|M.vanbaalenii_PYR-1 VVLKRLTDAVRDGDRVLGVVRGSAVNQDGRSNGLTAPNAPSQRDVITRAL
MAV_2370|M.avium_104 LLLKRLNDALRDGDRILAVVRGTAANQDGHTVNIATPSKTAQTAVYRAAL
Mflv_3395|M.gilvum_PYR-GCK AVLKRLSDAQRDGDRVLAVVRGSAVNQDGRSNGLMAPNPAAQMSVLRSAY
MLBr_02357|M.leprae_Br4923 VVLKRLTDAQRDGDRVLAIIRGSAVNQDGRSNGLMAPNPAAQVAVLRTAY
TH_2454|M.thermoresistible__bu VILKRLPDALRDGDRVIAVIRGGAVAQDGRTVGIMSPNGAAQRDLFRHTC
MMAR_3799|M.marinum_M VLLERLSDARRRGHSVLGVIVGSAVNQDGASNGLTAPNGPAQERVIRSAV
::: * .* * . : . : * . .** : : *. :* .
MSMEG_6767|M.smegmatis_MC2_155 QRAGVEPNDVAYVEAHGTGTPVGDPIEMRALAGALTTD-RDATRPLVIGS
MAB_2212|M.abscessus_ATCC_1997 KEAGIDPALVGYIEAHGTGTSVGDPLEAQALGHSYGRV-AGRARPLVIGS
Mb2959|M.bovis_AF2122/97 KLADVTPDSVNYVETHGTGTVLGDPIEFESLAATYGLGKGQGESPCALGS
Rv2934|M.tuberculosis_H37Rv KLADVTPDSVNYVETHGTGTVLGDPIEFESLAATYGLGKGQGESPCALGS
MUL_2016|M.ulcerans_Agy99 KLADATADSVNYVETHGTGTVLGDPIEFEALAATYGLGKDKGADSCALGS
Mvan_3124|M.vanbaalenii_PYR-1 RSADVAAGTVDYIETHGTGTGLGDPIEFDALAAVY----GKGEVPCALGA
MAV_2370|M.avium_104 AAAGVDAGTVGMVEAHGPGTPVGDPIEYASLAEVYG-----IDGPCALAS
Mflv_3395|M.gilvum_PYR-GCK AAAGVEPREVDYIEAHGTGTLLGDPIEARALGSVLGRG-RAADAPLLIGA
MLBr_02357|M.leprae_Br4923 ANAAMPPTAIDYVETHGTGTLLGDPIEARALGAVLGRG-RAEDSPLLIGA
TH_2454|M.thermoresistible__bu EITGTSPATVDFVEAHGTGTPTGDPVELDALAAVYGAA-HGPDDPCRVGS
MMAR_3799|M.marinum_M AAAGLRVADVDVVEAHGTGTTLGDPIEAHALLATYGAD-RDAEQPLWLGS
: : :*:**.** ***:* :* . :.:
MSMEG_6767|M.smegmatis_MC2_155 VKTNIGHLEAGAGVAGLIKAALIVKHGHIPANLHLKNPTRHVSLTELKLD
MAB_2212|M.abscessus_ATCC_1997 VKNNFGHTEAAAGVAGLIKAALTVQRRTIAPQVVLDKLNPEIPFDQLQIR
Mb2959|M.bovis_AF2122/97 VKTNIGHLEAAAGVAGFIKAVLAVQRGHIPRNLHFTRWNPAIDASATRLF
Rv2934|M.tuberculosis_H37Rv VKTNIGHLEAAAGVAGFIKAVLAVQRGHIPRNLHFTRWNPAIDASATRLF
MUL_2016|M.ulcerans_Agy99 VKTNLGHLEAAAGITSFIKATLAVAHGYIPPNLHFSRWNPAIDASSTRLF
Mvan_3124|M.vanbaalenii_PYR-1 VKTNMGHLEAAAGVAGFIKTVLSLQHGKIAPNLNFEKWNPQIDPKPTRLF
MAV_2370|M.avium_104 VKTNFGHAQAASGALGMMKAILALQHGVVPRNLHFTQLPDDLARIDTKLF
Mflv_3395|M.gilvum_PYR-GCK IKSNLGHTEAAAGIAGFAKTVLALQRGRIPANLDYQSPNPHIPFDNLRLK
MLBr_02357|M.leprae_Br4923 VKTNLGHLEAAAGIAGFIKTVLAVQRGQIPPNQRFESPNLHIPFAELRMK
TH_2454|M.thermoresistible__bu VKPNTGHLEGGAGVVGLIKAALALQHGVIPPTAGIRELTPAVDWATNGLH
MMAR_3799|M.marinum_M VKSNMGHTQAAAGVAGLIKMIQAINHAVLPPTLHVDAPSPHIDWSAGAVR
:* * ** :..:* .: * : : :. : :
MSMEG_6767|M.smegmatis_MC2_155 IPTIGRPFPE-CDR-RIAGINSFGFGGTNAHVVLAEP----------PAA
MAB_2212|M.abscessus_ATCC_1997 IPTEVEPYPD-LGAPAYAAVNSFGYGGTNAHVLVQEP----------PAP
Mb2959|M.bovis_AF2122/97 VPTESAPWPA-AAGPRRAAVSSFGLSGTNAHVVVEQA------PDTAVAA
Rv2934|M.tuberculosis_H37Rv VPTESAPWPA-AAGPRRAAVSSFGLSGTNAHVVVEQA------PDTAVAA
MUL_2016|M.ulcerans_Agy99 VPTQGAQWP---AGLRRAAVSSFGLSGTNAHVVLEQP------PAPAPAD
Mvan_3124|M.vanbaalenii_PYR-1 VPTEAQDWPK-SEHPRRAAVSSFGMGGTNAHIVLEQG------PEPAPAG
MAV_2370|M.avium_104 VPQQTTPWVSNGGHPRRAAVSSYGLSGTNVHAILEQA------PEPAPET
Mflv_3395|M.gilvum_PYR-GCK VVDEVTDWKPVG-RPRVAGVSSFGFGGTNAHVVLEQA------PDPTPAE
MLBr_02357|M.leprae_Br4923 VVDKHMEWPDTG-HLRRAAVSSFGFGGTNAHVVIEQG------PELTPVT
TH_2454|M.thermoresistible__bu VPTTVEPFPRRADSPRRAAVCSYGYGGTIAHLLLEEAPAVDETPAAAPAP
MMAR_3799|M.marinum_M LLTEAVPWPD-TGRARTAGISSFGISGTNAHLIVQEAP-------QESTA
: : *.: *:* .** .* :: :
MSMEG_6767|M.smegmatis_MC2_155 RHSAETGDHRVLTVLPISARSEEALVATAGRLAGHLAAHP-EVTLADLGY
MAB_2212|M.abscessus_ATCC_1997 VQTEAP-ARDSIRIFPVSARSGSALHEVAGRYAKQLSSDLSQDGAQRLKT
Mb2959|M.bovis_AF2122/97 AGGMPYVSA-----LNVSGKTAARVASAAAVLADWMSGPGAAAPLADVAH
Rv2934|M.tuberculosis_H37Rv AGGMPYVSA-----LNVSGKTAARVASAAAVLADWMSGPGAAAPLADVAH
MUL_2016|M.ulcerans_Agy99 QP-RSGLSA-----LVVSGKTPQRVAAMASALADWVDGPGAQTPLADVAH
Mvan_3124|M.vanbaalenii_PYR-1 AA-DTGVVT-----LVVSGKTSERLAASARSLADWLDGDGADVPLVDVAY
MAV_2370|M.avium_104 VAPEGISAESPLL-FPLSSTSADELRRTAGRLADWVHAHG-DLALPDLAY
Mflv_3395|M.gilvum_PYR-GCK DTDVAPAAASPVTTLVVAGKSAPRIATTAGMLAEWLAGDGADVPLDQVAH
MLBr_02357|M.leprae_Br4923 ECSSN----TAVSTLVVTGKTASRVAAMAGMLADWVEGPGAEVALADVAH
TH_2454|M.thermoresistible__bu AADAADANSPRFHVIPVSARSGARLARHAAALRGHLS---AGADLTAVAA
MMAR_3799|M.marinum_M DPSPSDVCEPLFRVWPVSGRTAEALNAQAERLGQYLVDHP-DLDLTDLAY
::. : : * : :
MSMEG_6767|M.smegmatis_MC2_155 TLSHRRAHLNHRHTFVVD-----SIDEARRQLQAVADGGQISAG---RAG
MAB_2212|M.abscessus_ATCC_1997 AATARRAQHYLRKGFIYR-----DADDLLAQLNTYAASDEAAPPRALVEG
Mb2959|M.bovis_AF2122/97 TLNRHRARHAKFATVIAR-----DRAEAIAGLRALAAGQ-PRVGVVDCDQ
Rv2934|M.tuberculosis_H37Rv TLNRHRARHAKFATVIAR-----DRAEAIAGLRALAAGQ-PRVGVVDCDQ
MUL_2016|M.ulcerans_Agy99 TLNHHRARHGKFGAVVAR-----DRAGAVEGLRALAAGQ-PGPGVLGCQD
Mvan_3124|M.vanbaalenii_PYR-1 TVNHHRSRYQTIATVCAR-----THAEAVTGLRALADGR-PAPGVIAPHD
MAV_2370|M.avium_104 TLARRRVHRPVRTAVLAG-----DRAQLIEALREVADGDTPYPAAVGRGD
Mflv_3395|M.gilvum_PYR-GCK SLNHHRAQHSKFATVCTR-----DRAGALAGLQALAAGH-TAPGVVP-PH
MLBr_02357|M.leprae_Br4923 TLNHHRSRHAKFGTVVAR-----DRIQAVAGLRALAAGK-QAPGVVG-QQ
TH_2454|M.thermoresistible__bu TMWQRRSHEPVRAAVIAR-----HPGELVAGLDAIATDT-RHPAVVAGSV
MMAR_3799|M.marinum_M SLATTRAHHAYRAAVTVPGDTVNTRDDLLAGLRSLAVDQFHPGVTYHHYR
: * : . * * .
MSMEG_6767|M.smegmatis_MC2_155 EARL-------AFVCTGMGPQWWQMCRGLLDVFPVFTDSIHRTDRELSRY
MAB_2212|M.abscessus_ATCC_1997 ISDP-------VFVFSGMGPQWWGMARALLERPGIFRDAAAEIDEVFQEI
Mb2959|M.bovis_AF2122/97 HAG----GPGRVFVYSGQGSQWASMGQQLLANEPAFAKAVAELDPIFVDQ
Rv2934|M.tuberculosis_H37Rv HAG----GPGRVFVYSGQGSQWASMGQQLLANEPAFAKAVAELDPIFVDQ
MUL_2016|M.ulcerans_Agy99 VQN----QPGTVFVYSGQGSQWVGMGRQLLADEPSFAAAIAELEPDFVAQ
Mvan_3124|M.vanbaalenii_PYR-1 AKGGVAAGKGVVFLYSGQGAQWAGMGKTLLTSEPAFAAAVDELEPAFVEK
MAV_2370|M.avium_104 RG--------PVWVFSGQGSQWAAMGADLLATEPVFAATVAQAEPLIARE
Mflv_3395|M.gilvum_PYR-GCK QGSC---RPGKVFVYSGQGAQWTGMGRRLLADEPAFAAAVAELEPVFVEQ
MLBr_02357|M.leprae_Br4923 DGTP---GSGTVFVYSGRGSQWAGMGRQLLADEPAFTAAVAELEPVFVVH
TH_2454|M.thermoresistible__bu LPAA---EAGAVWVFSGHGSHWPGMGRELLEHEPVFAAVIDEIEPVFRAE
MMAR_3799|M.marinum_M LGQAG----KTVFVFPGQGAQYAGMGAGLYRHHPVFTTAIDEICAVMDEH
.:: .* *.:: * * * . :
MSMEG_6767|M.smegmatis_MC2_155 ADWSLLEELTRDEASSRMGETEFAQPANFAIQVALAEQLAHFGITPDAVI
MAB_2212|M.abscessus_ATCC_1997 SGWSVIAELLRPQADSRVSRTEIAQPANFLVQSALAKHLQQFGIRPTAVV
Mb2959|M.bovis_AF2122/97 VGFSLQQTLI---DGDEVVGIDRIQPVLVGMQLALTELWRSYGVIPDAVI
Rv2934|M.tuberculosis_H37Rv VGFSLQQTLI---DGDEVVGIDRIQPVLVGMQLALTELWRSYGVIPDAVI
MUL_2016|M.ulcerans_Agy99 AGFSLQQTLT---EGREVVGIDRIQPVLVGIQLALTALWRSHGVTPDAVV
Mvan_3124|M.vanbaalenii_PYR-1 VGFSLRQTLE---AGEPVVGIDRIQPVLVGMQLALTALWRSYGVEPDAVI
MAV_2370|M.avium_104 SGFSVAEAMS---APQTVTGQDRVQPTLFTMQVALAATMKAHGVRPGAVI
Mflv_3395|M.gilvum_PYR-GCK VGFSLQQILA---GGETVTGIDRIQPVLVGMQLALTELWRAYGVHPDAVI
MLBr_02357|M.leprae_Br4923 AGFSLHDVLA---NGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVI
TH_2454|M.thermoresistible__bu LGFSPRQALQ---SGE-LGGTDRVQALTFAVQAGLAAVLRDRGVKPAAVI
MMAR_3799|M.marinum_M LDVPLRDVMFT--EPGLLQQTVYAQPALFAFGVAMHAVLTQAGVNPDYLL
. . : : * . . : *: * ::
MSMEG_6767|M.smegmatis_MC2_155 GHSAGEVAAHHIAGLLTFEQAVHVIYHRSRLQQRTTGQGRMLAVGLDAET
MAB_2212|M.abscessus_ATCC_1997 GHSVGEVAAAYVSGALSLRDAATVSFHRSRLQAKTAGSGGMLAVGLDAEE
Mb2959|M.bovis_AF2122/97 GHSMGEVSAAVVAGALTPEQGLRVITTRSRLMARLSGQGAMALLELDADA
Rv2934|M.tuberculosis_H37Rv GHSMGEVSAAVVAGALTPEQGLRVITTRSRLMARLSGQGAMALLELDADA
MUL_2016|M.ulcerans_Agy99 GHSMGEVSAAVVAGALTPADGFKVIATRSRLMARLAGQGAMALLELDSDA
Mvan_3124|M.vanbaalenii_PYR-1 GHSMGEATAAVVAGVLTPAEGFDVIATRTRLMKRLSGQGAMALLELDAQA
MAV_2370|M.avium_104 GHSLGEAAAAVVAGALSLEDGARVICRRSRLMSRVAGTGATASVELPAQQ
Mflv_3395|M.gilvum_PYR-GCK GHSMGEVAASVVAGALSVADGLKVIATRSKLMSRLSGQGAMALIELDPDA
MLBr_02357|M.leprae_Br4923 GHSLGEVAAAVVAGALTAAEGLRVTATRSRLMAPLSGQGGMALLELDAVE
TH_2454|M.thermoresistible__bu GHSVGEVAACVAAGVFDLARGAAVACYRARGFRSVAGKGAMALVGLPFED
MMAR_3799|M.marinum_M GHSVGELTAAHVAGVLSLEEAAVLVCARGRLMQSCTP-GAMMAISASEPA
*** ** :* :* : . : * : : * :
MSMEG_6767|M.smegmatis_MC2_155 LMQILDEKILDQFGRRVSVAAINSPSAVTVAGDADVLEDIARHLDEAQIF
MAB_2212|M.abscessus_ATCC_1997 AQRRAAR-----FGSAVCVAAINSTAATTLSGDSAALQTLHDELAGDGIF
Mb2959|M.bovis_AF2122/97 AEALIAGY------PQVTLAVHASPRQTVIAGPPEQVDTVIAAVATQNRL
Rv2934|M.tuberculosis_H37Rv AEALIAGY------PQVTLAVHASPRQTVIAGPPEQVDTVIAAVATQNRL
MUL_2016|M.ulcerans_Agy99 AEALIADY------PQVTLAVHASPHQSVVAGPPESVDAVIAAVAGQNRL
Mvan_3124|M.vanbaalenii_PYR-1 TEKLIADR------SDVTIAVYASPKQTVIAGPPEQVDELVAAVDAQGKL
MAV_2370|M.avium_104 VLSELTARG----ISDVVVAVVASPQSTVIAGAAPTVRDLVTAWQERGVM
Mflv_3395|M.gilvum_PYR-GCK ATALIADY------PDVTLAVYASPRQTVIAGPPDQVDAVIAAVSAQDRL
MLBr_02357|M.leprae_Br4923 TEALIVDY------SQVTLAIYNSPRQTVIAGPTEQIDELIDRVRAQNRF
TH_2454|M.thermoresistible__bu ARQRLGER------TDVVAAISASPLSTVISGTVDAVGEVSAAWAEQGVM
MMAR_3799|M.marinum_M VAAMLENH------PEVVIAAVNGPTSVAVAGPAEQLNALREHCNISNHK
* * .. .::* : :
MSMEG_6767|M.smegmatis_MC2_155 NRYLAVKVPYHTHYMETIKDDLHTAFASLSSKAATLPLYSTVTGELLD-R
MAB_2212|M.abscessus_ATCC_1997 ARMLHVEVPYHSQLMDPILGELATALAGLTPRKAAVPVYSTVTGEKMHSA
Mb2959|M.bovis_AF2122/97 ARRVEVDVASHHPIIDPILPELRSALADLTPQPPSIPIISTT--YESAQ-
Rv2934|M.tuberculosis_H37Rv ARRVEVDVASHHPIIDPILPELRSALADLTPQPPSIPIISTT--YESAQ-
MUL_2016|M.ulcerans_Agy99 ARRIEVDVASHHPIIDPILPDLRSALADLTPQPPAIPMITTT--CEQPQ-
Mvan_3124|M.vanbaalenii_PYR-1 ARRIEVDVASHHPTIDPVLPELREALAYLTPAAPKIPLVSTVG-YAGDA-
MAV_2370|M.avium_104 AREVPTDVAFHSPQVDPIMDDLTDALAEISPRPPEVPYYSATL-FDPREQ
Mflv_3395|M.gilvum_PYR-GCK ARRIEVDVASHHPTIDPILPELREALSGLRPVSPNIPIVITTR-EHDGPE
MLBr_02357|M.leprae_Br4923 ASRVNIEVAPHNPAMDALQPQMRSELADVAPRTPTIPILSTTY-ADLGSC
TH_2454|M.thermoresistible__bu VRKVNTDVAFHSPAMDALTAELARLTSTLTPKPAAVPLYSTAL-ADPRST
MMAR_3799|M.marinum_M VTLLRVSHAFHSPAMDPILAEFEAIAKRLTYRPHSVPIMSNLTGSLATVE
: . . * ::.: :: : :*
MSMEG_6767|M.smegmatis_MC2_155 YDAGAAYWWQNTRATVLFEPAMRRMLDDGYTHFVELGPHPVLAASILESA
MAB_2212|M.abscessus_ATCC_1997 AFAEPDYWCKNVRDSVLFAKAVDTLIVDRYRVFLELGPHPVLLGNIRESF
Mb2959|M.bovis_AF2122/97 PVADADYWSANLRNPVRFHQAVTAAGVD-HNTFIEISPHPVLTHALTDTL
Rv2934|M.tuberculosis_H37Rv PVADADYWSANLRNPVRFHQAVTAAGVD-HNTFIEISPHPVLTHALTDTL
MUL_2016|M.ulcerans_Agy99 PVLDADYWAANLRNPVRFHQAITTAGAQ-HHTFVEISPHPLLTHAITDTL
Mvan_3124|M.vanbaalenii_PYR-1 PMYSADYWAANLRNPVRFSQAVHDASAE-NSNFIEISPHPLLTHAISDTL
MAV_2370|M.avium_104 PVCDARYWANNMRRMVRFATAVQAALEDGYRVFAELAPHPLLVRALEQTA
Mflv_3395|M.gilvum_PYR-GCK PVFDADYWVDNLRNPVRFEQAVAAAGAE-IGTFIEVSPHPLLTYGISDTL
MLBr_02357|M.leprae_Br4923 PVFDAQHWATNMRNPVHFQQAIMTAGTD-HRTFIEISAHPLLTQAITDTL
TH_2454|M.thermoresistible__bu AARDEHYWVANLRGRVRFAEAVTAAAEDGHRLFLEVSAHPVVCHSMAETL
MMAR_3799|M.marinum_M QLTSARYWAQHLRKPVRFYDGVTRLLAGGEQAFVELSPHPVLAAAITDTL
:* : * * * .: * *:..**:: : ::
MSMEG_6767|M.smegmatis_MC2_155 GTQRVSVDASQ--RRGQDDA-RTLLNCVGALHSRGHEVAWDMVQPRAG--
MAB_2212|M.abscessus_ATCC_1997 VRHSVSGAAIQTLHRDQDDE-QSVLQAIADLYAVGAIDAPGQADIYESGV
Mb2959|M.bovis_AF2122/97 DPD-GSHT--VMSTMNR-----ELDQTLY-FHAQLAAVG---VAASEHTT
Rv2934|M.tuberculosis_H37Rv DPD-GSHT--VMSTMNR-----ELDQTLY-FHAQLAAVG---VAASEHTT
MUL_2016|M.ulcerans_Agy99 AAA-DSRTRLITATLQR-----DGDDAIT-FHTNLAAVG---KKPADAVT
Mvan_3124|M.vanbaalenii_PYR-1 AAQSTSRRYHVGATVNR-----DNPEPLA-FHAQLAAVRPPAVQAPEGTP
MAV_2370|M.avium_104 RSREIPMAALAGMRRGQ-----ALPHGLRGFVADLHNAGAAVDFSVLYPT
Mflv_3395|M.gilvum_PYR-GCK GTSHH--HSVPTLLRETGSEGDEASDETLSFHTNLNSTFTTKPPVSDHGP
MLBr_02357|M.leprae_Br4923 HGTRC--ISIGTLQRD--------ADDTVTFHTNLNNVHTVHPPHTPHPA
TH_2454|M.thermoresistible__bu ALAEVGEHAVLPVLRREQPELPAVAAVVGALYCHGAPVRPAFPPGTRWAT
MMAR_3799|M.marinum_M TGVTDRVGSAVVTTLRRD---RPDMDMVASAIANLHVHGHSPSWQKIYPG
MSMEG_6767|M.smegmatis_MC2_155 AHPVKLPSYPWQTKRFWN-DTHEAE--EALFYRPVHPLLGQPVRA----V
MAB_2212|M.abscessus_ATCC_1997 VPHMDLPKYPWSQEEVWEEDPLTLR--ARYGDADRFALLGDRVDA----L
Mb2959|M.bovis_AF2122/97 GRLVDLPPTPWHHQRFWVTDR-----SAMSELAATHPLLGAHIEMPRNGD
Rv2934|M.tuberculosis_H37Rv GRLVDLPPTPWHHQRFWVTDR-----SAMSELAATHPLLGAHIEMPRNGD
MUL_2016|M.ulcerans_Agy99 GQLADIPVTPWQHTQFWVEDR-----SGISELVAAHPLLGVHIEVPSGHD
Mvan_3124|M.vanbaalenii_PYR-1 GRLADIPPTAWQHSPYWMVDR-----SAGQGFSGAHPLLGLHVELPSGTG
MAV_2370|M.avium_104 GRLVDAPLPTWTHRRLWLTDGGLESPTHGGCTVAVHPLLGPHVHLQEEPE
Mflv_3395|M.gilvum_PYR-GCK EPHPVLPATPWHHTRHWVAHKKVDR-RGPS-APRPGTLLGDLTSVATSPP
MLBr_02357|M.leprae_Br4923 EPHVTIPSTPWQHTRHWIPRKRSVN-SIGL-APQVGTLLGQHTAVSGILP
TH_2454|M.thermoresistible__bu G----LPGTQWQHRRFWRTPGTPPG-GVGVHDVDSHTLLGGRIDVAGAVP
MMAR_3799|M.marinum_M ATTVELPTYPFQHRRYWLDPAPRADVSAAGLDQPEHPLLAAVTELADQDQ
* : * .**.
MSMEG_6767|M.smegmatis_MC2_155 HPTWEAEFSTLTVPFLADHQVQGSVVVPGAVYVEMALAAGRETYG-SDLS
MAB_2212|M.abscessus_ATCC_1997 TPQWEVTLAPANLPWLPDHTVLGSVVLPGTAYLDAALSAVRQRSGRAQAG
Mb2959|M.bovis_AF2122/97 -HVWQTDVGTEVCPWLADHKVFGQPIMPAAGFAEIALAAASEALGTAADA
Rv2934|M.tuberculosis_H37Rv -HVWQTDVGTEVCPWLADHKVFGQPIMPAAGFAEIALAAASEALGTAADA
MUL_2016|M.ulcerans_Agy99 -HVWQADVGTKACPWLGDHKVFGQAIMPAAGFAEIALAAASEAFDLPVDA
Mvan_3124|M.vanbaalenii_PYR-1 -HVWQSDVGVQAHPWLADHIVHGLAVMPGAGFAEIALAAGREALGLPATG
MAV_2370|M.avium_104 RHLWQADVGTAAQPWLADHQIRNVVVLPGAAYCEMALAAARSVLGATAEV
Mflv_3395|M.gilvum_PYR-GCK THLWQARLVRDAKPYPGFHRIQGVEVVPMSVLLRTLAAAAAESGASALAD
MLBr_02357|M.leprae_Br4923 IHLWQARLAPQAKPYRGWHRVHGVEVVPASIVLRTILCAAAELGYSTLFE
TH_2454|M.thermoresistible__bu ARVWQTRLDLSTRPYPGDHPVQGTEIVPAAVLLNTFLTAAG----SDIAD
MMAR_3799|M.marinum_M -IVLSGRLSTSAHRWLAGHQLGDTVVLPATALIDMALYAGEHTGCPTIDE
. . : * : . ::* : *
MSMEG_6767|M.smegmatis_MC2_155 VDN------LVLHRAVILDDTCDPVIRTTVDQDDGSVEFAALI-------
MAB_2212|M.abscessus_ATCC_1997 LDS------VVFAVPLVVADHDAPITRITVDEP---TKRFTVN-------
Mb2959|M.bovis_AF2122/97 VAPNIVINQFEVEQMLPLDGHTPLTTQLIRGGDSQIRVEIYSR-------
Rv2934|M.tuberculosis_H37Rv VAPNIVINQFEVEQMLPLDGHTPLTTQLIRGGDSQIRVEIYSR-------
MUL_2016|M.ulcerans_Agy99 LS----INQLEIEQMLDLDEHTQVTTQLTRRADDKTRIEIYSR-------
Mvan_3124|M.vanbaalenii_PYR-1 VE-----VQLEVEQMLPLDDHTKLTTQLTRDDEENLRVEIHSR-------
MAV_2370|M.avium_104 RD-------IRFEQALLLDEQTTVDASASVSSPGVLHFTVQS--------
Mflv_3395|M.gilvum_PYR-GCK IRFDRPVVVDQPQVIQVVAHGDTITMASAPHADAPANR------------
MLBr_02357|M.leprae_Br4923 IRFEQPIFANLPRLIQVVVDNQLISLASSPATETPQHR------------
TH_2454|M.thermoresistible__bu VRLRTPVAPARTRDVQVVLQDRALALASRIVGEDTTARATAGRDTTDRDT
MMAR_3799|M.marinum_M LVLQTPLTLTPDAATDLQISVAAPDEQNRRTFSVHARTSEHPH-------
MSMEG_6767|M.smegmatis_MC2_155 --------------ATADTDLKWVITATAELNTLPRAPRAGDTGGGAVTS
MAB_2212|M.abscessus_ATCC_1997 --------------GRSAHTQLWTAHANGRLVEANLGSKRIDVSAWSAND
Mb2959|M.bovis_AF2122/97 -------------TRGGEFCRHATAKVEQSPRECAHAHPEAQGPATGTTV
Rv2934|M.tuberculosis_H37Rv -------------TRGGEFCRHATAKVEQSPRECAHAHPEAQGPATGTTV
MUL_2016|M.ulcerans_Agy99 -------------SASG-WRRHAVAKAETSTPSAAPVLEERTSRQDETDI
Mvan_3124|M.vanbaalenii_PYR-1 -------------SDAGSWTRHAVGTVKAAAG---PAPAKVVPASDGTPV
MAV_2370|M.avium_104 -------------HQGGEQARHASAVLGAATDEQPAAHDLSALLTAHPHD
Mflv_3395|M.gilvum_PYR-GCK ------------------WVRHATARVAQPRPADTGAVDVTAATD-----
MLBr_02357|M.leprae_Br4923 ------------------WTRHVTAQLSSASARSAVPSDHPDQINGHLEV
TH_2454|M.thermoresistible__bu TACDTTDRDTTACDDPGVWLTHCTARVADDHVGAEGVLDEEAIRARCPQP
MMAR_3799|M.marinum_M --------------QHSTWVLHASGTLSNAPSTTPPTKPLPGPQAITKVN
MSMEG_6767|M.smegmatis_MC2_155 --TDGDTFYQRTQALGFDYGEAFRSVASVTAG--RDWAVAQIDIPQSISA
MAB_2212|M.abscessus_ATCC_1997 RVFDGEDVYKGLSAVGLSYGPAFQRIQSVRIG--SAGCVAQLASPESVSA
Mb2959|M.bovis_AF2122/97 --SPAD-FYALLRQTGQHHGPAFAALSRIVRL-ADGSAETEISIPDEAP-
Rv2934|M.tuberculosis_H37Rv --SPAD-FYALLRQTGQHHGPAFAALSRIVRL-ADGSAETEISIPDEAP-
MUL_2016|M.ulcerans_Agy99 --KPAD-LYALLRQAGQNHGPAFAALTRILRR-PDGSVETEITLSDEAP-
Mvan_3124|M.vanbaalenii_PYR-1 --SPSD-FYTALRRTGAHHAHAFAALTRIVR--AGGRADTEIVLPDEAT-
MAV_2370|M.avium_104 --DDGDEVRRRMDRRGVQYGPAFAGLGAVHSGDETGTVLAEVALPRQIRS
Mflv_3395|M.gilvum_PYR-GCK --YDRSTVEELQSRWGVEGQPFPWSIETCR---ATSDGVLAEVRWQD---
MLBr_02357|M.leprae_Br4923 ISDPIPDVASLLALCGVDGLPFEWSVKSWAKKTQQSTSRTVEIEFPDTL-
TH_2454|M.thermoresistible__bu --LPAGHVVDTLAGLGVAAMGFGWEVLELHR--GEGELFARVAAEPDKS-
MMAR_3799|M.marinum_M ----QESFYDQLAQHGLHYSEAFRSIQGIGKDPLNPDAICAEVALPADIE
. * :
MSMEG_6767|M.smegmatis_MC2_155 DVDTYRFHPALIDGAFQTLFGAPFSGQEENTDP--YLPTRIRHCAVYGPP
MAB_2212|M.abscessus_ATCC_1997 QR--HAVHPALADAALQCIAVLLAARPELDIPPTAHVPASIDRVRLYGEV
Mb2959|M.bovis_AF2122/97 RHPGYRLHPVVLDAALQSVGAAIPDGEIAGSAEASYLPVSFETIRVYRDI
Rv2934|M.tuberculosis_H37Rv RHPGYRLHPVVLDAALQSVGAAIPDGEIAGSAEASYLPVSFETIRVYRDI
MUL_2016|M.ulcerans_Agy99 RHQGYRIHPAMLDAALQSLAAAVPNDEFAGSAEASYLPVSFETLRVYSNP
Mvan_3124|M.vanbaalenii_PYR-1 PHRGIALHPVMLDAALQGLAAAMSDETLSDSTDVTYLPVGFGSIRVFGDI
MAV_2370|M.avium_104 QQAAYGAHPALLDACFQSVEAHPAVRALGDGALG--LVLGIRRLRAYGAA
Mflv_3395|M.gilvum_PYR-GCK ------------GSAVALLDAAVQVARLADINDDRLLVPAAVESLTATGE
MLBr_02357|M.leprae_Br4923 ----------PDGAIAPLLDAAILIPALADVTETQFYVPASIKQVWLGDT
TH_2454|M.thermoresistible__bu ----------APATWAGLIDAATSTASTIFDGPPRLRMPARIERVHVRDK
MMAR_3799|M.marinum_M THG-YGIHPALLDAALHPLTAALADTN---TNSGPQLPFAIAGITLHATG
:
MSMEG_6767|M.smegmatis_MC2_155 AEHMTVRARVLS--------------------------------------
MAB_2212|M.abscessus_ATCC_1997 PEDPVAVVEITSTQPLCANAYLASRDGEVALAMTGVTLRPVGSASTPLSE
Mb2959|M.bovis_AF2122/97 GRHVRCRAHLTNL-------------------------------------
Rv2934|M.tuberculosis_H37Rv GRHVRCRAHLTNL-------------------------------------
MUL_2016|M.ulcerans_Agy99 GRHARCRAQLTNLN------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 GRRAKCRAELVSVV------------------------------------
MAV_2370|M.avium_104 RNAHYCYTRVTKA-------------------------------------
Mflv_3395|M.gilvum_PYR-GCK LLASSGTVTVRRRP------------------------------------
MLBr_02357|M.leprae_Br4923 ATGPCGAVTLNRTA------------------------------------
TH_2454|M.thermoresistible__bu PP-AIALLHVRRRP------------------------------------
MMAR_3799|M.marinum_M ASRMHVQLEPTATD------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 ------------------------ATHDAVECDITITDPSGGVLAAFDGF
MAB_2212|M.abscessus_ATCC_1997 LEQYFYEPRWEPLEEEIEGQPAPTTTAPAARPANVIVEIAQVPLAVAEGA
Mb2959|M.bovis_AF2122/97 ------------------------DGGTGKMGRIVLINDAGHIAAEVDGI
Rv2934|M.tuberculosis_H37Rv ------------------------DGGTGKMGRIVLINDAGHIAAEVDGI
MUL_2016|M.ulcerans_Agy99 ------------------------DGGAGKLGRITLTDDAGNVTVEITDI
Mvan_3124|M.vanbaalenii_PYR-1 ------------------------EDSGDAMGRVTLTDDTGTVLAQVDDV
MAV_2370|M.avium_104 -------------------------DTSGVEADIDVLDEHGAVLLAVQGL
Mflv_3395|M.gilvum_PYR-GCK ------------------------GTGEDLVLDVAVT----VPDDSTR--
MLBr_02357|M.leprae_Br4923 ------------------------CDDDGITVDVTVADGSGVPLALMRSL
TH_2454|M.thermoresistible__bu ---------------------------EGTVTDVTIAE----ESGAVS--
MMAR_3799|M.marinum_M ------------------------------TFRLSATDPVGAPVITIDSL
MSMEG_6767|M.smegmatis_MC2_155 TVQSLSASSRMSADHIDKGLFALEWSPVTDT-------------------
MAB_2212|M.abscessus_ATCC_1997 RRAAAAGVVVLNADTVEKANLAVTFAEALDRDEFLRVLVTVGSGKSAVEN
Mb2959|M.bovis_AF2122/97 YLRR--VERRAVPLPLEQKIFDAEWT------------------------
Rv2934|M.tuberculosis_H37Rv YLRR--VERRAVPLPLEQKIFDAEWT------------------------
MUL_2016|M.ulcerans_Agy99 YLRR--VERRSVPLPLAQKIFDTEWV------------------------
Mvan_3124|M.vanbaalenii_PYR-1 HLKR--VQRRTVPLPLSQKIFDSRWV------------------------
MAV_2370|M.avium_104 RVGTSASESGTRDRVLTERLLNIEWR------------------------
Mflv_3395|M.gilvum_PYR-GCK ---------------VDIVGLRYVDV------------------------
MLBr_02357|M.leprae_Br4923 RYRA---------LDLDNAQQDYSTV------------------------
TH_2454|M.thermoresistible__bu ---------------VTLTGMGFEEL------------------------
MMAR_3799|M.marinum_M TVRS----------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2212|M.abscessus_ATCC_1997 VAGLVTVAQSLRMVMEAETERGVVSPDVQAVLVSKNAFLAPGDRDLDLDQ
Mb2959|M.bovis_AF2122/97 --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
MMAR_3799|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 ------------------------PDTAHGDESTWLILTDNGGVGEAIAD
MAB_2212|M.abscessus_ATCC_1997 AALVGARRVLANEQHPAKWSLVDLPAAVSAEEVTAEIGAMNRAEEVAVRQ
Mb2959|M.bovis_AF2122/97 ------------------------ESPIAAVPAPEPAAETTRGSWLVLAD
Rv2934|M.tuberculosis_H37Rv ------------------------ESPIAAVPAPEPAAETTRGSWLVLAD
MUL_2016|M.ulcerans_Agy99 ------------------------EKSIAGADQPD-----APGSWLVLTD
Mvan_3124|M.vanbaalenii_PYR-1 ------------------------ESAAAAG-------TTATGSWLALAD
MAV_2370|M.avium_104 ------------------------QRELPEPE------HADAASWLLIGT
Mflv_3395|M.gilvum_PYR-GCK ------------------------QAGPAEAAPADPRSVAHEIAWRPWTA
MLBr_02357|M.leprae_Br4923 ------------------------FVESHVDALTDARNFVHAIDWQPRTD
TH_2454|M.thermoresistible__bu ------------------------ENPGGGGSSGDLTGMLHHLRWHPVDW
MMAR_3799|M.marinum_M ----------------------LPDTDLTQPPTHKAQQGIFELTWPALPA
MSMEG_6767|M.smegmatis_MC2_155 GLR-----------------------------------------------
MAB_2212|M.abscessus_ATCC_1997 GLRWTQRMRRSLPELVAPWEEPFEPTDPEVAYEVQIPDTRTLKDIKLRAC
Mb2959|M.bovis_AF2122/97 ATV-----------------------------------------------
Rv2934|M.tuberculosis_H37Rv ATV-----------------------------------------------
MUL_2016|M.ulcerans_Agy99 A-------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 G-------------------------------------------------
MAV_2370|M.avium_104 T-------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK P-------------------------------------------------
MLBr_02357|M.leprae_Br4923 LD------------------------------------------------
TH_2454|M.thermoresistible__bu P-------------------------------------------------
MMAR_3799|M.marinum_M ETFP----------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2212|M.abscessus_ATCC_1997 DRIEPGPRQVEVRVETVGLNYKDPLKVLGILTERELGKTYFKLEPGMEGF
Mb2959|M.bovis_AF2122/97 --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
MMAR_3799|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 ----------------------LRGHHVHTVAHDPTGEIDWPDMLATHLS
MAB_2212|M.abscessus_ATCC_1997 GVITRVGSQVTEVRVGESIAVAERGLLRRYLTFDLDGGAAWEPIADVHLQ
Mb2959|M.bovis_AF2122/97 ----DAPGKAQAKSMADDFVQQWRSPMRRVHTADIHDESAVLAAFAETAG
Rv2934|M.tuberculosis_H37Rv ----DAPGKAQAKSMADDFVQQWRSPMRRVHTADIHDESAVLAAFAETAG
MUL_2016|M.ulcerans_Agy99 ------------KSNADEFVARWSSPQRRVITADLGDEAAMLAAFAETAG
Mvan_3124|M.vanbaalenii_PYR-1 ---------AAGQAAAQDFASRFGADTRRVITADLGDESAVREAFATATA
MAV_2370|M.avium_104 ---------ATADVLASTLADTLKNHGAQCTTMAWP-QQADHTAHAEQLR
Mflv_3395|M.gilvum_PYR-GCK ---------SETAPAGASLAVVGSGTTADALRERLAAAGYTDADEAT---
MLBr_02357|M.leprae_Br4923 ---------CSNTPVASSGSVAVIGDARAGFGLLLKEAGYTLAAPADGVS
TH_2454|M.thermoresistible__bu ----------DTDPPAAVVLVGGDARTRAFVTRDLDEARVAHRSYADP--
MMAR_3799|M.marinum_M -------------ATGVLPPWALISPHPENLSPDLNQSPTYPNLTALPTC
MSMEG_6767|M.smegmatis_MC2_155 -------------------------------------------GERTGLI
MAB_2212|M.abscessus_ATCC_1997 RDEFDPLAVGSGVPFFTAGYAFYKLADVRPGETVLIHGAAGGMGMAAVQV
Mb2959|M.bovis_AF2122/97 DPEHPP-----------------------------VGVVVFVGGASSR--
Rv2934|M.tuberculosis_H37Rv DPEHPP-----------------------------VGVVVFVGGASSR--
MUL_2016|M.ulcerans_Agy99 DPERLP-----------------------------VGVVVFVGGAGNNSG
Mvan_3124|M.vanbaalenii_PYR-1 DPDLPP-----------------------------VGVVVFCDFGGNP--
MAV_2370|M.avium_104 NQWRGDG---------------------------FTGVVVLTGPKNGD--
Mflv_3395|M.gilvum_PYR-GCK -----------------------------------AQCVLYVPGPD----
MLBr_02357|M.leprae_Br4923 E----------------------------------VRYVVYVADPHPA--
TH_2454|M.thermoresistible__bu --------------------------------------AALPPDLTAG--
MMAR_3799|M.marinum_M PP-----------------------------------LVIWDLTTPQP--
MSMEG_6767|M.smegmatis_MC2_155 DCWPLEVTDAATDPAGTATVLRIVKALATLDGVTPRLYLVTANAQPAAGT
MAB_2212|M.abscessus_ATCC_1997 AANMGAVVYATAGSEERRRAALDLGATAAFDSRSVGFVDDILQITEGRGV
Mb2959|M.bovis_AF2122/97 -------LDDELAAARDTVWSITTVVRAVVGTWHGRS-PRLWLVTGGGLS
Rv2934|M.tuberculosis_H37Rv -------LDDELAAARDTVWSITTVVRAVVGTWHGRS-PRLWLVTGGGLS
MUL_2016|M.ulcerans_Agy99 TADDGRISYDGLIQSRDTVWQISTVVRAIVGTWHGRA-PRLWLVTEGGLV
Mvan_3124|M.vanbaalenii_PYR-1 ATLDGTDVAGGLEHARDVIWGVAGTVRAIVGSWHGKA-PRLWLVTQGGLV
MAV_2370|M.avium_104 ------NDQESALLSRDHVQHLVRIARELT-DLPGEP-PRLYVVTRNAQT
Mflv_3395|M.gilvum_PYR-GCK --------GDDLDATVRLCGEVASLVSRLADRPGTGE-PRLWILTEG---
MLBr_02357|M.leprae_Br4923 -----TTAETDVDFAVRITAEISDLVRALAKREPGKP-VALWIVTRG---
TH_2454|M.thermoresistible__bu -----TVVLVLPRTAARPAASAQLVLHTLQRLSATNSGARLWVLTRG---
MMAR_3799|M.marinum_M -------PQSDLLHQVHTLTQHTLAGLQNWLNRSDTLQAHLVVLTRHAVT
MSMEG_6767|M.smegmatis_MC2_155 ELTGTELTGVEQAAFWGLG----RVIGHQELGEYWGGLIDIDHADAP---
MAB_2212|M.abscessus_ATCC_1997 DVIYNSLPGEMIAQNFAVAGEFCRIIEIGKADIYFGGATDLKPFSGN---
Mb2959|M.bovis_AF2122/97 VADD-EPGTPAAASLKGLVR-----VLAFEHPDMRTTLVDLDITQDP---
Rv2934|M.tuberculosis_H37Rv VADD-EPGTPAAASLKGLVR-----VLAFEHPDMRTTLVDLDITQDP---
MUL_2016|M.ulcerans_Agy99 VHD--KPGRPAIGALQGLVR-----VLAYEHPELRATLVDLDTGADA---
Mvan_3124|M.vanbaalenii_PYR-1 VSPEDGQGNPGANSLKGLAR-----VLAYEHPDLKTTLLDTGSDG-----
MAV_2370|M.avium_104 VLPN-DVPNLGQAGLRGLVR-----VIGMEHPQLGAGQIDVDESTD----
Mflv_3395|M.gilvum_PYR-GCK VRDADSAQSLPHSSLWGLAG-----VVGAEQPQLWGGLVDVAS---GAD-
MLBr_02357|M.leprae_Br4923 VYESVASSALRQSFLWGFGG-----VIAAEHPEMWGGLVDLAASALGADR
TH_2454|M.thermoresistible__bu VHEGTDPG---HGPLWGLAR-----VAAAEHPQLWGGLLDIGE-------
MMAR_3799|M.marinum_M TSPHDLAPDPAQAATAALIH------TTQNEHPNRITLIDIDNTPTTS--
.. : *
MSMEG_6767|M.smegmatis_MC2_155 ---SSTAEQICGHVLGDGAEDQIALR------------------------
MAB_2212|M.abscessus_ATCC_1997 ---LSFHSIDMDRMLRLRPEIFRELRRECTEMLTAGKLTPLPYTRFPIEE
Mb2959|M.bovis_AF2122/97 --LTALSAELRNAGSGSRHDDVIAWR------------------------
Rv2934|M.tuberculosis_H37Rv --LTALSAELRNAGSGSRHDDVIAWR------------------------
MUL_2016|M.ulcerans_Agy99 --VTRLAGELSSPRDDPNYDDVVAWR------------------------
Mvan_3124|M.vanbaalenii_PYR-1 ---AALATEIEAASASAVTEDVIAWR------------------------
MAV_2370|M.avium_104 --AQALARQLLAGSE----EDETAWR------------------------
Mflv_3395|M.gilvum_PYR-GCK ---LDETAKALAGVLPVAAKSILSLR------------------------
MLBr_02357|M.leprae_Br4923 DDILDQFGPTLASLLQTPTRSIVVLR------------------------
TH_2454|M.thermoresistible__bu ------DRLPVRALTALTGHGVVVVR------------------------
MMAR_3799|M.marinum_M -QTLTNILTTLTNPTSAPTEPQLALR------------------------
*
MSMEG_6767|M.smegmatis_MC2_155 --------------GNQILAPRLRPCSGLT-KPFPTKLT-----------
MAB_2212|M.abscessus_ATCC_1997 VVGAFEAVFRAEHMGRIVLDLRDQTPTLLPRKPEPAPVR-----------
Mb2959|M.bovis_AF2122/97 --------------GERRFVERLSRATIDVS-KGHPVV------------
Rv2934|M.tuberculosis_H37Rv --------------GERRFVERLSRATIDVS-KGHPVV------------
MUL_2016|M.ulcerans_Agy99 --------------DGHRYVTQLCRAILDPEPQRDPVI------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------GGTRYVERLSRATLPAT-PGQLVV------------
MAV_2370|M.avium_104 --------------DGAWYTARLCPAPLLPEERHTAVANHECDGMRLQIR
Mflv_3395|M.gilvum_PYR-GCK --------------GGEFFAPELAALAS---DPVREPLR-----------
MLBr_02357|M.leprae_Br4923 --------------DGVVLAPTLVPIRS---EPVRKSLQ-----------
TH_2454|M.thermoresistible__bu --------------DGVAHTARLAPAGPGARDSAGEGLR-----------
MMAR_3799|M.marinum_M --------------HGTPHTPRLTPTTTETTTTSPPLEFD----------
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2959|M.bovis_AF2122/97 --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2370|M.avium_104 TPGDLESLELVACDRIPPGPGQIEVAVSASSINFADVLVAFGRYPAFEGR
Mflv_3395|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
MMAR_3799|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2959|M.bovis_AF2122/97 --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2370|M.avium_104 LPELGTDFAGVVTAVGPDVTDHKVGDHVGGLSANGCWGTFLTCDARLAVT
Mflv_3395|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
MMAR_3799|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2959|M.bovis_AF2122/97 --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2370|M.avium_104 LPPGLADDQAAAVTTAHATAYYGLHELARIGAGDRVLIHSATGGVGQAAI
Mflv_3395|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
MMAR_3799|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2959|M.bovis_AF2122/97 --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2370|M.avium_104 AIARAAGAEIFATAGSEQRRQLLRDMGIEHVYDSRTVEFADLIRHDTDGY
Mflv_3395|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
MMAR_3799|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2959|M.bovis_AF2122/97 --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2370|M.avium_104 GVDIVLNSVTGAAQRAGIELLAFGGRFVEIGKRDIYGDTRLGLLPFRRNL
Mflv_3395|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
MMAR_3799|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2959|M.bovis_AF2122/97 --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2370|M.avium_104 TFYALDLALMSFSHPDRLRGLLRTVYRLTADGALPMPESTHYPLADAASA
Mflv_3395|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
MMAR_3799|M.marinum_M --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155 ------------------------------------ADATYVVTGGAGAL
MAB_2212|M.abscessus_ATCC_1997 ------------------------------------PGHSYLITGGFGGF
Mb2959|M.bovis_AF2122/97 -----------------------------------RQGASYVVTGGLGGL
Rv2934|M.tuberculosis_H37Rv -----------------------------------RQGASYVVTGGLGGL
MUL_2016|M.ulcerans_Agy99 -----------------------------------RPGASYIVTGGLGGL
Mvan_3124|M.vanbaalenii_PYR-1 -----------------------------------RRDGAYVVTGALGGV
MAV_2370|M.avium_104 IRVMSAAQHTGKLVLDVPHAGRSRVVVPPAQVRAFRSDGAYIVTGGLGGL
Mflv_3395|M.gilvum_PYR-GCK ----------------------------------CRPDAAYLITGGLGAL
MLBr_02357|M.leprae_Br4923 ----------------------------------CKSDGAYLITGGMGAL
TH_2454|M.thermoresistible__bu ----------------------------------CSPGGTYLITGGTGAL
MMAR_3799|M.marinum_M ------------------------------------PAGTVLITGGTGML
: ::**. * .
MSMEG_6767|M.smegmatis_MC2_155 GRVVATYLAERG----ARHITLLGRSPISPRDRWASITEDDAHHATVDAI
MAB_2212|M.abscessus_ATCC_1997 GLATARSLARAG----ATHLILASRS-------------GAATEVARAQI
Mb2959|M.bovis_AF2122/97 GLVVARWLVDRG----AGRVVLGGRSDPTD--------------EQCNVL
Rv2934|M.tuberculosis_H37Rv GLVVARWLVDRG----AGRVVLGGRSDPTD--------------EQCNVL
MUL_2016|M.ulcerans_Agy99 GLVVARWLVDSG----AGRVVLNGRSEPSD--------------EQRKVL
Mvan_3124|M.vanbaalenii_PYR-1 GMAVVRWLVDHG----AGRLVLNGRSGPSD--------------EVAAEL
MAV_2370|M.avium_104 GLFLAEKMASPGSRAGCGRIVLCSRALPNP--------------KALATL
Mflv_3395|M.gilvum_PYR-GCK GLVTAEWLADRG----ARRVVLAGRTALPPRRRWDDDDLDKDARDKIAAV
MLBr_02357|M.leprae_Br4923 GLLMADWLADRG----ARRLVLMGRTPLPPRRDWELDTLDAGLRQKIDAI
TH_2454|M.thermoresistible__bu GLRLAHRLADLG----ARRLVLVSRSGMPARDSWG----RAGDSDTVAAI
MMAR_3799|M.marinum_M GAVFAEHMIARYG---ARHLLLVSRSGPDAP-------------GADDLY
* . : . :: * .*:
MSMEG_6767|M.smegmatis_MC2_155 RAIERLGAHVSTASVDITDSDQVRAWLREHTGSGGRPVRGIVHAAGSVRD
MAB_2212|M.abscessus_ATCC_1997 EALRAADVDVWEEQVDISDYDQVADLIAKVEASG-HPLRGVFHAAAVAHD
Mb2959|M.bovis_AF2122/97 AELQTR-AEIVVVRGDVASPGVAEKLIETARQS-GGQLRGVVHAAAVIED
Rv2934|M.tuberculosis_H37Rv AELQTR-AEIVVVRGDVASPGVAEKLIETARQS-GGQLRGVVHAAAVIED
MUL_2016|M.ulcerans_Agy99 AELESR-AEVVVVCGDSATEGVAESLVAAAEDQ-QRQLRGIVHGAAVIDD
Mvan_3124|M.vanbaalenii_PYR-1 DTLSHR-AEIAVVTGDVAEPGVAERLVAAAEET-GKPLRGLIHSAAVLED
MAV_2370|M.avium_104 ERIRQMGADIVVERGDIAEAGTAQRLLDVATAT-GLPVRGVLHLAAVIED
Mflv_3395|M.gilvum_PYR-GCK RALELRGVAVELAPVDIGSRDAVEALLTRRDEQGAPPIRGVIHGAGLTDS
MLBr_02357|M.leprae_Br4923 CALEMRGVTVEAVAVDVGHHDDVQALLAKRDRDGAAPIRGIIHAAGVTND
TH_2454|M.thermoresistible__bu TALEERGVSVRVAALDIGAPGAAARLREVLAD--LPDVRGVIHAAGVEAG
MMAR_3799|M.marinum_M QRLTQLGAQITITACDASDPTALAALLGSIPPQ--HPLRVVIHTAAVLHD
: . : * :* :.* *. .
MSMEG_6767|M.smegmatis_MC2_155 QLLVNMGEDDFAEVLAPKITGTRVLHNVFE--DHDL--EFFVMFGSAGST
MAB_2212|M.abscessus_ATCC_1997 EVIADISAESLRKVFRPKVQGALNLDKVTR--EHDVPLDHFVLYSSISGL
Mb2959|M.bovis_AF2122/97 SLVFSMSRDNLERVWAPKATGALRMHEAT----ADCELDWWLGFSSAASL
Rv2934|M.tuberculosis_H37Rv SLVFSMSRDNLERVWAPKATGALRMHEAT----ADCELDWWLGFSSAASL
MUL_2016|M.ulcerans_Agy99 SLLFSMTKDSLERVWAPKAAGALRLHDAT----ATRELDWWLGFSSTASL
Mvan_3124|M.vanbaalenii_PYR-1 EIFVGMTRESLDKIWAPKAAGALRLHEVT----AGSDLDWWVGFSSIVSL
MAV_2370|M.avium_104 ATLANITDELIERDWAAKVYGAWNLHCALQESGAEQSLDWFCSFSSAAAL
Mflv_3395|M.gilvum_PYR-GCK QLLTDIDDERLRRTLWPKVAGARVLHELFP----TDSVDFLYLTASAGTV
MLBr_02357|M.leprae_Br4923 QLVTNMTDDPVRQVMWPKIAGCQVLHEAFP----PGSVDFFYLTSSAAGI
TH_2454|M.thermoresistible__bu ALLTNTTAEDIEATMRPKVDGVLALHEVFP----PGRLDWLVLFSSCGYL
MMAR_3799|M.marinum_M AVLTELNPDQLDKVLAAKADAAWHLHQLTA----DADLDAFVLFSSAAGI
. : . .* . :. : .*
MSMEG_6767|M.smegmatis_MC2_155 IAAPGQGNYAAANAFLDAFAHHRQGLGLPALTIGWGPWSVG--MVEELGL
MAB_2212|M.abscessus_ATCC_1997 IGIVPQLTYAAANSVLDGLAASRRAAGLPALSVSWGAMSGGG-MAESDAI
Mb2959|M.bovis_AF2122/97 LGSPGQAAYACASAWLDALVGWRRASGLPAAVINWGPWSEVG-------V
Rv2934|M.tuberculosis_H37Rv LGSPGQAAYACASAWLDALVGWRRASGLPAAVINWGPWSEVG-------V
MUL_2016|M.ulcerans_Agy99 LGSPGQTAYACASAWLDGLVAWRRAAGLPAATINWGPWSEVG-------V
Mvan_3124|M.vanbaalenii_PYR-1 LGSPGQAAYACANAWLDGLVAWRTAAGLPALAVNWGQWADVG-------L
MAV_2370|M.avium_104 VGSPGQGAYAAANSWLDAFTRWRRARGLKATAIAWGAWAQIG-------R
Mflv_3395|M.gilvum_PYR-GCK FGVPGQGAYAAGNAYLDGLARARRREGGVTASLDWVAWRGLGFGSDAQVV
MLBr_02357|M.leprae_Br4923 FGIPGQGSYAAANSYLDALARTRRQQGCHTMSIDWVAWRGLGFAANAQIV
TH_2454|M.thermoresistible__bu GGFPGQGAYACGNAYLDAFARYRRASGDATTSVAWTAWRGLGMGSASDFV
MMAR_3799|M.marinum_M LGAQGQANYAAANAFLDALAYRRCRDHLPATSLAWGYWQNSGIAAHLDTL
. * **...: **.:. * : : *
MSMEG_6767|M.smegmatis_MC2_155 EKVYAQRGIELITPAVGARIIDRLLSQSVPAVVAMNADWSRARQVGFGGL
MAB_2212|M.abscessus_ATCC_1997 VKFLDSVGLRRLNMDMGAAFMRECSRFPLSHVAIAGIDWGVLRTPLPSTA
Mb2959|M.bovis_AF2122/97 AQALVGSVLDTISVAEGIEALDSLLAADRIRTGVARLRADRALVAFPEIR
Rv2934|M.tuberculosis_H37Rv AQALVGSVLDTISVAEGIEALDSLLAADRIRTGVARLRADRALVAFPEIR
MUL_2016|M.ulcerans_Agy99 AQALVGTPLDPITPAEGLVALDALLAADRGRTGVARLRSDRALIAFPEIR
Mvan_3124|M.vanbaalenii_PYR-1 ASTLRFSVLDPITPAEGVEALGGVMAAGFSRVGIARLRLDRAAAAFPEIQ
MAV_2370|M.avium_104 GAALADSADVAITPDEGAYAFEALLRHDRACTGYAPITGTPWLTAFAQR-
Mflv_3395|M.gilvum_PYR-GCK IDELERQGSRPVTPAEAFAAWEYASRFDVAHVVMAPTLDADEDTDQAAES
MLBr_02357|M.leprae_Br4923 SDELQRMGSRDITPSEAFTAWEYVDAYDVAQAVVLPVPRSYGSAGSTAGD
TH_2454|M.thermoresistible__bu AAQLDALGMGTVDVDDAMRALDAAIRDGDPNVVVLPLSPAAAAVPMFADV
MMAR_3799|M.marinum_M DQARLTRNLIPITTEHGLALFDAALVSQQPHLVPAPLNTRTLARHARQGS
: .
MSMEG_6767|M.smegmatis_MC2_155 VPKMFGELGTADTVGGQDGVGPSILELLAHTADADRPAVIAEQVRRLVAA
MAB_2212|M.abscessus_ATCC_1997 KSTRFAHLSAEAAAVSNE--QAAFRAAVLALPEEERGPMVTKELAKELAN
Mb2959|M.bovis_AF2122/97 SISYFTQVVEELDSAGDLGDWGGPDALADLDPGEARRAVTERMCARIAAV
Rv2934|M.tuberculosis_H37Rv SISYFTQVVEELDSAGDLGDWGGPDALADLDPGEARRAVTERMCARIAAV
MUL_2016|M.ulcerans_Agy99 NLGYFTLVVQELDAAGDGGDWAGPEALKEMDPAEARQVVTERLHTRIAAV
Mvan_3124|M.vanbaalenii_PYR-1 QIGFFADLVGELETDDVDEDWGGVEALKSMDAAEVNRVVVARLRRRISAI
MAV_2370|M.avium_104 -----SPFAEAFRANG--QSATGTSKLRAELEELPPEEWSTRLRRLISDQ
Mflv_3395|M.gilvum_PYR-GCK G---PERDWSQMSADDVVSE------------------LESGLRTILAVE
MLBr_02357|M.leprae_Br4923 SYLVPARNWSQMEAAEVRKE------------------LESGLRTIIAAE
TH_2454|M.thermoresistible__bu APADPDADAPGGEVPDGLSDGFPADGFPDD--GDLAEWVHRRVIAAVAGE
MMAR_3799|M.marinum_M LPAILSALTTTRRQAATTSIAALATQLAGETPQQQLATLTTLVTRVTATA
MSMEG_6767|M.smegmatis_MC2_155 VFDCAVTDIEPDDM----LDDIGLDSMMAMDFRVRINSAFSIDLPVLEIL
MAB_2212|M.abscessus_ATCC_1997 VLKVDVDSIDPKGP----IADLGIDSLMAVEFAARAGKQLNIQISAFQFT
Mb2959|M.bovis_AF2122/97 MGYTDQSTVEPAVPLDKPLTELGLDSLMAVRIRNGARADFGVEPPVALIL
Rv2934|M.tuberculosis_H37Rv MGYTDQSTVEPAVPLDKPLTELGLDSLMAVRIRNGARADFGVEPPVALIL
MUL_2016|M.ulcerans_Agy99 MGYADRSAVDASMP----LTELGLDSLMAVRIRNTARADFGVEPPVTLIL
Mvan_3124|M.vanbaalenii_PYR-1 MGYSDDNAVDTAQP----LTELGLDSLMAVRMRNTIRGDFGVEPPVALLL
MAV_2370|M.avium_104 VSLILRRNVDPDRP----LPEYGLDSLGGLELLTRIQTETGIRVSPADIA
Mflv_3395|M.gilvum_PYR-GCK LRIGD-DEVDSDRP----LAEMGLNSVMAMSIRREVEKLAGIELSATMLW
MLBr_02357|M.leprae_Br4923 LRVAE-AELDTDRP----FAELGLNSLMAMAIRREAEQFIGIELSAIMLF
TH_2454|M.thermoresistible__bu LGLAE-TDVDPRLP----LVEIGVDSIMTVALRRQLERQTGLTLPPTLLW
MMAR_3799|M.marinum_M LAHPDPTAIDPDLP----FKDLGVDSLSALELRNGLTREIGRALPATLIF
: ::. : : *::*: : : . . :
MSMEG_6767|M.smegmatis_MC2_155 RGVSVNSLSARILAELRDIHGVAPVEPDTGETASEPTTTDDDVERLLQDL
MAB_2212|M.abscessus_ATCC_1997 PDLTLEAVGARVALLIAQGVGDPDHDGI----------------------
Mb2959|M.bovis_AF2122/97 QGASLHDLTADLMRQLGLNDPDPALNNADTIRDRARQRAAARHGAAMRRR
Rv2934|M.tuberculosis_H37Rv QGASLHDLTADLMRQLGLNDPDPALNNADTIRDRARQRAAARHGAAMRRR
MUL_2016|M.ulcerans_Agy99 QGASLHDLTVDVIRQLDLAGDEQTHEHVDVVRDRAQQRAAARHGAAMRRK
Mvan_3124|M.vanbaalenii_PYR-1 QGATLADLALDLIRQLGLEEQE-SAERPNALRERAQQRAAARQRAASRRK
MAV_2370|M.avium_104 AIGTIRGL-------------------ADLLRDKLTPAGAAQAERV----
Mflv_3395|M.gilvum_PYR-GCK NYPTIGALAAYLAEKVAPQAVAE----AAEEDSGDSLLDSLFDSVEN---
MLBr_02357|M.leprae_Br4923 NHPTVALLAAYLTKVVAPQHDSQGDEMAALSASAGGVLDSLFDRIESTST
TH_2454|M.thermoresistible__bu EHPTAGAVSDRIVEMLRARG------------------------------
MMAR_3799|M.marinum_M DHPTPAAVAYHLQSQLIGDTAALGPIGQLLQAICDADLRLTLIEVVLALS
: :
MSMEG_6767|M.smegmatis_MC2_155 SEAEMRQLLAELEASGTEAGGAIS--------------------------
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2959|M.bovis_AF2122/97 PKPAVQGG------------------------------------------
Rv2934|M.tuberculosis_H37Rv PKPEVQGG------------------------------------------
MUL_2016|M.ulcerans_Agy99 RG------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 VGPRS---------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02357|M.leprae_Br4923 EAEGLV--------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
MMAR_3799|M.marinum_M GLDSSFISNFGSSRNPQATTLRSAENVALRLVCISEFEGQYKRFAYGLPE
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2959|M.bovis_AF2122/97 --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
MMAR_3799|M.marinum_M SIEVIEVLAPGFSGTVLPTSVQESGEMIIDALQRNDSYGRDAVIVGHGIT
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2959|M.bovis_AF2122/97 --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
MMAR_3799|M.marinum_M CIAAIHALELMDASLSPLTKPQTALVAISPIAAIDALSISEDPFALATFS
MSMEG_6767|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2212|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2959|M.bovis_AF2122/97 --------------------------------------------------
Rv2934|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2016|M.ulcerans_Agy99 --------------------------------------------------
Mvan_3124|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2370|M.avium_104 --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02357|M.leprae_Br4923 --------------------------------------------------
TH_2454|M.thermoresistible__bu --------------------------------------------------
MMAR_3799|M.marinum_M THLRNEQDLIAFGRYLNFGLHSKDKLDEERSLILTPHIRGHQVGAAESPL
MSMEG_6767|M.smegmatis_MC2_155 ------------------------
MAB_2212|M.abscessus_ATCC_1997 ------------------------
Mb2959|M.bovis_AF2122/97 ------------------------
Rv2934|M.tuberculosis_H37Rv ------------------------
MUL_2016|M.ulcerans_Agy99 ------------------------
Mvan_3124|M.vanbaalenii_PYR-1 ------------------------
MAV_2370|M.avium_104 ------------------------
Mflv_3395|M.gilvum_PYR-GCK ------------------------
MLBr_02357|M.leprae_Br4923 ------------------------
TH_2454|M.thermoresistible__bu ------------------------
MMAR_3799|M.marinum_M ALEPATVALRILNWLTDNNMLDSA