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M. tuberculosis H37Rv Rv2931 (ppsA)

annotation: PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA
coordinates: 3245445 - 3251075
length: 1876

MTGSISGEADLRHWLIDYLVTNIGCTPDEVDPDLSLADLGVSSRDAVVLSGELSELLGRTVSPIDFWEHP
TINALAAYLAAPEPSPDSDAAVKRGARNSLDEPIAVVGMGCRFPGGISCPEALWDFLCERRSSISQVPPQ
RWQPFEGGPPEVAAALARTTRWGSFLPDIDAFDAEFFEISPSEADKMDPQQRLLLEVAWEALEHAGIPPG
TLRRSATGVFAGACLSEYGAMASADLSQVDGWSNSGGAMSIIANRLSYFLDLRGPSVAVDTACSSSLVAI
HLACQSLRTQDCHLAIAAGVNLLLSPAVFRGFDQVGALSPTGQCRAFDATADGFVRGEGAGVVVLKRLTD
AQRDGDRVLAVICGSAVNQDGRSNGLMAPNPAAQMAVLRAAYTNAGMQPSEVDYVEAHGTGTLLGDPIEA
RALGTVLGRGRPEDSPLLIGSVKTNLGHTEAAAGIAGFIKTVLAVQHGQIPPNQHFETANPHIPFTDLRM
KVVDTQTEWPATGHPRRAGVSSFGFGGTNAHVVIEQGQEVRPAPGQGLSPAVSTLVVAGKTMQRVSATAG
MLADWMEGPGADVALADVAHTLNHHRSRQPKFGTVVARDRTQAIAGLRALAAGQHAPGVVNPADGSPGPG
TVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEPVFVEQAGFSLHDVLANGEELVGIEQIQLGLIGMQL
ALTELWCSYGVRPDLVIGHSMGEVAAAVVAGALTPAEGLRVTATRSRLMAPLSGQGGMALLELDAPTTEA
LIADFPQVTLGIYNSPRQTVIAGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADL
TPRTPTIGIISTTYADLHTQPVFDAEHWATNMRNPVRFQQAIASAGSGADGAYHTFIEISAHPLLTQAII
DTLHSAQPGARYTSLGTLQRDTDDVVTFRTNLNKAHTIHPPHTPHPPEPHPPIPTTPWQHTRHWITTKYP
AGSVGSAPRAGTLLGQHTTVATVSASPPSHLWQARLAPDAKPYQGGHRFHQVEVVPASVVLHTILSAATE
LGYSALSEVRFEQPIFADRPRLIQVVADNRAISLASSPAAGTPSDRWTRHVTAQLSSSPSDSASSLNEHH
RANGQPPERAHRDLIPDLAELLAMRGIDGLPFSWTVASWTQHSSNLTVAIDLPEALPEGSTGPLLDAAVH
LAALSDVADSRLYVPASIEQISLGDVVTGPRSSVTLNRTAHDDDGITVDVTVAAHGEVPSLSMRSLRYRA
LDFGLDVGRAQPPASTGPVEAYCDATNFVHTIDWQPQTVPDATHPGAEQVTHPGPVAIIGDDGAALCETL
EGAGYQPAVMSDGVSQARYVVYVADSDPAGADETDVDFAVRICTEITGLVRTLAERDADKPAALWILTRG
VHESVAPSALRQSFLWGLAGVIAAEHPELWGGLVDLAINDDLGEFGPALAELLAKPSKSILVRRDGVVLA
PALAPVRGEPARKSLQCRPDAAYLITGGLGALGLLMADWLADRGAHRLVLTGRTPLPPRRDWQLDTLDTE
LRRRIDAIRALEMRGVTVEAVAADVGCREDVQALLAARDRDGAAPIRGIIHAAGITNDQLVTSMTGDAVR
QVMWPKIGGSQVLHDAFPPGSVDFFYLTASAAGIFGIPGQGSYAAANSYLDALARARRQQGCHTMSLDWV
AWRGLGLAADAQLVSEELARMGSRDITPSEAFTAWEFVDGYDVAQAVVVPMPAPAGADGSGANAYLLPAR
NWSVMAATEVRSELEQGLRRIIAAELRVPEKELDTDRPFAELGLNSLMAMAIRREAEQFVGIELSATMLF
NHPTVKSLASYLAKRVAPHDVSQDNQISALSSSAGSVLDSLFDRIESAPPEAERSV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2931ppsA-100% (1876)PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA
M. tuberculosis H37RvRv2932ppsB0.069.62% (938) phenolpthiocerol synthesis type-I polyketide synthase PPSB
M. tuberculosis H37RvRv2933ppsC0.046.51% (1561) phenolpthiocerol synthesis type-I polyketide synthase PPSC

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2956ppsA0.099.63% (1876) phenolpthiocerol synthesis type-I polyketide synthase PPSA
M. gilvum PYR-GCKMflv_3395-0.055.51% (1888) acyl transferase domain-containing protein
M. leprae Br4923MLBr_02357-0.075.95% (1888) polyketide synthase
M. abscessus ATCC 19977MAB_0939-0.037.38% (1086) polyketide synthase
M. marinum MMMAR_1776ppsA0.083.87% (992) phenolpthiocerol synthesis type-I polyketide synthase PpsA
M. avium 104MAV_2370-0.034.66% (1431) mycocerosic acid synthase
M. smegmatis MC2 155MSMEG_6767-0.030.95% (1877) mycocerosic acid synthase
M. thermoresistible (build 8)TH_2454-0.036.72% (1819) PUTATIVE beta-ketoacyl synthase
M. ulcerans Agy99MUL_2019ppsA0.083.67% (992) phenolpthiocerol synthesis type-I polyketide synthase PpsA
M. vanbaalenii PYR-1Mvan_3128-0.057.76% (1887) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


MAB_0939|M.abscessus_ATCC_1997      MDSAENPIESTPRFAIIGYAARFPGAADAEEFWDVLREGRDAISEVPADR
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      WDAEEFFDPEPGAPGKVVTRRAGFVEDVTGFDAPFFGMSTREVRLMDPQH
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      RLLLETAWRAVEHSGIAPTDLAETNSGVFVGLATHDYLGMASDELTFPEI
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      EAYMAIGTSNAAAAGRISYRLGLQGPSVAVDTACSSSLVAIHQACQALQL
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      GECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDAAADGYVRGEG
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      SGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      DALKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAGAAYGIGRETNDPLLI
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      GSAKTNIGHLEAAAGIAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLP
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      VEVVREARPWGRNGRPRIAGVSSFGFAGTNAHVILEEAPVVSRDAVEPPA
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      PAGGRKFSILPLSARTPAALAQLADKYRAWLNAHPEAALADLCFTAGVGR
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      AHLEHRAALVVNTREAAVELLSAVADDRPAPGLGRGESHDTPKTAWLFTG
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      QGSQYPGMARELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVDGPEA
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      EETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAE
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      VFSLEDGARLIAERGRLFSSLPAGGRMAAVFTDAERAERLTDEFPSLSVA
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      AYNGANTVLSGPAQDLEKAIAALVADGVRCDFLETSHAFHSALLDPILDE
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      FEAYANQFNYKTPQRILIDNRTGTALGRSVKLDGAYWRRHARQPVEFAKS
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      VRTLADMNCKVLLEIGPQPVLTAAALRAWPDPATAPRAIASLRRNTADHR
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      QITEAAADAYVLGHLPDFGAFQHAPARKLDLPTYPFERRQYWFSDKRDGD
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      NRDAGNRQQNNGGPRTEAVRLLEDGKIEELANLLGGVDGDQQTLNVLTKL
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      AAQHNLQRTTQTIADDRYQFRWEKSPTPLSGSQAAGGVTWLLVADAAGAA
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      QPLLDVLTARGQQHRVLALPVSDADEAELVEALRSAADEDSALRIVHVAA
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      LAGQGSSSAQSLLRIQHQVLGGTRRLFRAAAAAELRAPIWIVTRGAQHVI
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      EGDTVAPEQSALWGFGRAAALELPQVWGGLADLSDAGTDEWAQFIGRVSV
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      SGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVRSDATYLVTGGLG
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      SIGLEIAGYLAGRGAKHLVLTSRREPGEAARQRIDALAAQGCEVRAVTAD
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      VADGHDVARLLAGIQAELPPLAGIVHAAGEIGTTPLSDLEDAEVDRVFAG
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      KVWGAWHLSEAAAGLKLDFFINTSSIAAVWGGYGQTAYSAANAFLDGLAW
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      RLREQGIAGTSVNFGPWSAGMADAESRARLEQRGIKTLSPTDALAGLADV
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      VAASGSNAVQGVIARIDWARFLPLYQQAGKRGFLAELDREVPSHLAGVAG
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      AQSGSTQLVERLANAPVQQRKKLLTDYLRDAVAEVTRVDVSEIREDAGFF
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         -------------MTGSISGEADLRHWLIDYLVTNIGCTPDEVDPDLSLA
Mb2956|M.bovis_AF2122/97            -------------MTGSISGEADLRHWLIDYLVTNIGCTPDEVDPDLSLA
MLBr_02357|M.leprae_Br4923          -------------MTASIGSEADLCHWLVNYLVTNIGCTPDEVDLNLSLT
MMAR_1776|M.marinum_M               -------------MTPSIGGEADLRHWLVDYLVTNIGCPPDEVDPNLSLA
MUL_2019|M.ulcerans_Agy99           -------------MTPSIGGEADLRHWLVDYLVTNIGCPPDEVDPNLSLA
Mflv_3395|M.gilvum_PYR-GCK          -------------MTSAFD-EDAIRNWLVDYLVTNIGCSPDEIDFDAPLN
Mvan_3128|M.vanbaalenii_PYR-1       -------------MTSAFD-EDAIRNWLVDYLVTNIGCSPDEINFDAPLN
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      DLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGDVLGLA
MAV_2370|M.avium_104                --------------------------------------------------
Rv2931|M.tuberculosis_H37Rv         DLGVSSRDAVVLSGELSELLGRTVSPIDFWEHPTINALAAYLAAPEPSPD
Mb2956|M.bovis_AF2122/97            DLGVSSRDAVVLSGELSELLGRTVSPIDFWEHPTINALAAYLAAPEPSPD
MLBr_02357|M.leprae_Br4923          DLGMSSRDAVVLSGELTDLLGKTVSPIDFWEHPTINALAAYLIAPAPDPE
MMAR_1776|M.marinum_M               DLGVSSRDAVVLSGELTELLGRTVSPIDFWEHPTINDLAAYLTAPEPSTG
MUL_2019|M.ulcerans_Agy99           DLGVSSRDAVVLSGELTELLGRTVSPIDFWEHPTINDLAAYLTAPEPSTG
Mflv_3395|M.gilvum_PYR-GCK          DLAVGSSDAVVLTGELSELLGRTVSPVEFWQYPTINALARFLTGGEVEAV
Mvan_3128|M.vanbaalenii_PYR-1       DLAVGSSDAVVLTGELSELLGRTVSPVEFWQYPTINALAKFLTGGEVEPA
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      EQAKPAAQLASAVTGRTDEPIAIVAVSCRFPGAPD-------PEAFWDVL
MAV_2370|M.avium_104                -----------------MVPVAVIGMACRLPGAVDS------PERLWEAL
Rv2931|M.tuberculosis_H37Rv         SDAAVKRGAR----NSLDEPIAVVGMGCRFPGG------ISCPEALWDFL
Mb2956|M.bovis_AF2122/97            SDAAVKRGAR----NSLDEPIAVVGMGCRFPGG------ISCPEALWDFL
MLBr_02357|M.leprae_Br4923          SESAPRRSVQ----GALEEPIAVIGMGCRFPGG------ISGPEALWQFL
MMAR_1776|M.marinum_M               AEAAVSRTVR----GSLEEPIAVVGMGCRFPGG------ISGPEALWQFL
MUL_2019|M.ulcerans_Agy99           AEAAVSRTVR----GSLEEPIAVVGMGCRFPGG------ISGPEALWQFL
Mflv_3395|M.gilvum_PYR-GCK          AEVSPIRRVS-------DDAIAVVGLGVRFPGGG---DDIHGPDDLWEFL
Mvan_3128|M.vanbaalenii_PYR-1       IEASVGGGVSRDY-GADDEPIAVIGLGCRFPGGDGLDGNITGPDAYWRFL
TH_2454|M.thermoresistible__bu      MSVDVTAKAR------PDDPIAIIGIGCRLAGR------ITSPEEFWGFL
MSMEG_6767|M.smegmatis_MC2_155      MPMPNTDHTS-------RQPLAIVGIGCRFPGG------ADSAQRYWDLL
                                                       .:*::.:. *:.*          .:  *  *

MAB_0939|M.abscessus_ATCC_1997      SGGVDAIREVPEDRFDIDEFYDPDPEVAGKTYTRFGGFLDGIDGFDPEFF
MAV_2370|M.avium_104                LRGDDFVTEIPPDRWDADEYYDPEPGVPGRSVSRWGAFIDDVAGFDPEFF
Rv2931|M.tuberculosis_H37Rv         CERRSSISQVPPQRWQPFEGGPPEVAAALARTTRWGSFLPDIDAFDAEFF
Mb2956|M.bovis_AF2122/97            CERRSSISQVPPQRWQPFEGGPPEVAAALARTTRWGSFLPDIDAFDAEFF
MLBr_02357|M.leprae_Br4923          CDRRSSIGQVPNERWELFDDGSPEVKALLARTTRWGSFLEDIDAFDSEFF
MMAR_1776|M.marinum_M               CDRKSSIGRVPDERWAQFDDGSPAVKALLARTTRWGSYLTDIDAFDADFF
MUL_2019|M.ulcerans_Agy99           CDRKSSIGRVPDERWAQFDDGSPAVKALLARTTRWGSYLTDIDAFDADFF
Mflv_3395|M.gilvum_PYR-GCK          AQGRSAVSQVPPTRWSWYDDGSPEGAAALAHTTRWGSYLSEIDEFDADYF
Mvan_3128|M.vanbaalenii_PYR-1       MEGRSAVRQVPEERWESFQINTPEAAAALAGTTRWGAFLRDLDAFDAEFF
TH_2454|M.thermoresistible__bu      LAGGSNVREIPAERWEPYLRRDPRNAAVLREITPWGTFLDDLAGFDAEFF
MSMEG_6767|M.smegmatis_MC2_155      CNNIDATREVPENRWNAAKYHDPNPAKIGKIVTRRGGFLDQIDQFDPQFF
                                        .   .:*  *:       *         :  * ::  :  **.::*

MAB_0939|M.abscessus_ATCC_1997      GISPREAVWIEPQQRLMLETVWEGLERAGYSPAALRGSRTGIFAGVGANE
MAV_2370|M.avium_104                GINEREATAMDPQHRLLLETSWEAMEHAGLTEERVADSRTGVFIGLTHGD
Rv2931|M.tuberculosis_H37Rv         EISPSEADKMDPQQRLLLEVAWEALEHAGIPPGTLRRSATGVFAGACLSE
Mb2956|M.bovis_AF2122/97            EISPSEADKMDPQQRLLLEVAWEALEHAGIPPGTLRRSATGVFAGACLSE
MLBr_02357|M.leprae_Br4923          EISPSEADKMDPQQRLLLEVAWEALEHAGISSNSLRRSQTGVFAGSCLSE
MMAR_1776|M.marinum_M               EISASEADKMDPQQRLLLEVAWEALEHAGIPPSSLRRSQTGVFAGSCLSE
MUL_2019|M.ulcerans_Agy99           EISASEADKMDPQQRLLLEVAWEALEHAGIPPSSLRRSQTGVFAGSCLSE
Mflv_3395|M.gilvum_PYR-GCK          EISPSEADKMDPQQRLLLEVTHEALEHAGIRPDVLRHTQTGVFVGACLGE
Mvan_3128|M.vanbaalenii_PYR-1       EISPSEADKMDPQQRLLLEVTQEALEHAGIPTHTLRHSQTGVFAAACLGE
TH_2454|M.thermoresistible__bu      GVSPREAELTDPQQRLALEVSWEALEHAGVPPRSLAGTDTAVLMGVNSDD
MSMEG_6767|M.smegmatis_MC2_155      GISPREAHSLDPQQRLLLQATWEALEDGGIPADELAGTDVGVFVGGFTLD
                                     :.  **   :**:** *:.  *.:* .*     :  : ..:: .    :

MAB_0939|M.abscessus_ATCC_1997      YAHLLSSES--IDKIEPYFITGNALNAISGRVAFALGFEGPAVAVDTACS
MAV_2370|M.avium_104                Y-QLLAADT--RSVEGAYGFSGSNFSLASGRIAYALGVHGPALTVDTACS
Rv2931|M.tuberculosis_H37Rv         YGAMASAD---LSQVDGWSNSGGAMSIIANRLSYFLDLRGPSVAVDTACS
Mb2956|M.bovis_AF2122/97            YGAMASAD---LSQVDGWSNSGGAMSIIANRLSYFLDLRGPSVAVDTACS
MLBr_02357|M.leprae_Br4923          YGAIASTD---LSQVDGWSNTGGAMSIIANRLSYFLDLRGPSVAVDTACS
MMAR_1776|M.marinum_M               YGAIASTD---LTQVDGWSNTGGAMSIIANRLSYFLDLRGPSVAVDTACS
MUL_2019|M.ulcerans_Agy99           YGAIASTD---LTQVDGWSNTGGAMSIIANRLSYFLDLRGPSVAVDTACS
Mflv_3395|M.gilvum_PYR-GCK          YAVMASKD---LAEVNAYSGTGGALSIIANRVSYFYDLRGPSVTIDTACS
Mvan_3128|M.vanbaalenii_PYR-1       YGYLSTVD---LGDVDSWSGTGGALSIIANRVSYYFDLRGPSVTIDTACS
TH_2454|M.thermoresistible__bu      YGRLLMED---LPGIEAWTGIGTSLCGIANRVSHLLDLRGPSVALDAACA
MSMEG_6767|M.smegmatis_MC2_155      YQLLQNQGRTSRYRFKPHSATGMMMTMLANRISHAFDFRGPSMAIDTACS
                                    *  :                 *  :   :.*::.  ...**::::*:**:

MAB_0939|M.abscessus_ATCC_1997      SALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVGRC
MAV_2370|M.avium_104                SGLTAIHLACRSLHEGESDLALAGGATLALDPRKFSAGSAEGMLSPTGRC
Rv2931|M.tuberculosis_H37Rv         SSLVAIHLACQSLRTQDCHLAIAAGVNLLLSPAVFRGFDQVGALSPTGQC
Mb2956|M.bovis_AF2122/97            SSLVAIHLACQSLRTQDCHLAIAAGVNLLLSPAVFRGFDQVGALSPTGQC
MLBr_02357|M.leprae_Br4923          SSLVAIHLACQSLRTADANLAIAAGVNLLLSPAVFRGFDQVGALSPTGCC
MMAR_1776|M.marinum_M               SSLVAIHLACQSLRMQDSNLAIAAGVNLLLSPAVFRGFDQVGALSPTGNC
MUL_2019|M.ulcerans_Agy99           SSLVAIHLACQSLRMQDSNLAIAAGVNLLLSPAVFRGFDQVGALSPTGNC
Mflv_3395|M.gilvum_PYR-GCK          SSLVAIHLACQSLRSGDSDVALAGGVNVILSPAVTRSFDQAEAMSKSGRC
Mvan_3128|M.vanbaalenii_PYR-1       SSLVTIHLACQSLRSGDSNMALAAGVNLLLSPAVTRSFDQLEAMSRTGQC
TH_2454|M.thermoresistible__bu      ASLVAVHNACQLLRAGETGLAIAGGVSALIGPGLTRVLDKAGATAPDGRC
MSMEG_6767|M.smegmatis_MC2_155      SSLVAVHLAAQSIWDGDCDVALAGGVNIMVGPNTAIAESKSGFLSPEGRS
                                    :.*.::* * : :   :  :*:*.*..  :.*      .     :  * .

MAB_0939|M.abscessus_ATCC_1997      KTFDASADGYVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGASS
MAV_2370|M.avium_104                HAFDVAADGFVGGEGSVMLLLKRLNDALRDGDRILAVVRGTAANQDGHTV
Rv2931|M.tuberculosis_H37Rv         RAFDATADGFVRGEGAGVVVLKRLTDAQRDGDRVLAVICGSAVNQDGRSN
Mb2956|M.bovis_AF2122/97            RAFDATADGFVRGEGAGVVVLKRLTDAQRDGDRVLAVICGSAVTQDGRSN
MLBr_02357|M.leprae_Br4923          RAFDAAADGFVRGEGAGVVVLKRLTDAQRDGDRVLAIIRGSAVNQDGRSN
MMAR_1776|M.marinum_M               RAFDAAADGFVRGEGAGVVVLKRLTDAQQDGDRVLAVICGSAINQDGRSN
MUL_2019|M.ulcerans_Agy99           RAFDAAADGFVRGEGAGVVVLKRLTDAQQDGDRVLAVICGSAINQDGRSN
Mflv_3395|M.gilvum_PYR-GCK          HAFDSRADGFVRGEGCGVAVLKRLSDAQRDGDRVLAVVRGSAVNQDGRSN
Mvan_3128|M.vanbaalenii_PYR-1       HAFDAGADGFVRGEGCGVTVLKRLSDAQRDGDRILAVIRGSAVNQDGRSN
TH_2454|M.thermoresistible__bu      KSFDASADGYGRGEGAAVVILKRLPDALRDGDRVIAVIRGGAVAQDGRTV
MSMEG_6767|M.smegmatis_MC2_155      KAFSDTADGYARGEGGAVVVIKPLAHALRDGDDIYAQILGTAVSQDGHTD
                                    ::*.  ***:  .**  : ::* * .* :*** : * : * *  *** : 

MAB_0939|M.abscessus_ATCC_1997      GLTVPNGGAQQRLIGSVLARAGLVGGDVDYLEAHGTGTPLGDPIEVQAAA
MAV_2370|M.avium_104                NIATPSKTAQTAVYRAALAAAGVDAGTVGMVEAHGPGTPVGDPIEYASLA
Rv2931|M.tuberculosis_H37Rv         GLMAPNPAAQMAVLRAAYTNAGMQPSEVDYVEAHGTGTLLGDPIEARALG
Mb2956|M.bovis_AF2122/97            GLMAPNPAAQMAVLRAAYTNAGMQPSEVDYVEAHGTGTLLGDPIEARALG
MLBr_02357|M.leprae_Br4923          GLMAPNPAAQVAVLRTAYANAAMPPTAIDYVETHGTGTLLGDPIEARALG
MMAR_1776|M.marinum_M               GLMAPNPAAQQAVLRAAYTNAGMQPSEVDYVEAHGTGTLLGDPIEARALG
MUL_2019|M.ulcerans_Agy99           GLMAPNPAAQQAVLRAAYTNAGMQPSEVDYVEAHGTGTLLGDPIEARALG
Mflv_3395|M.gilvum_PYR-GCK          GLMAPNPAAQMSVLRSAYAAAGVEPREVDYIEAHGTGTLLGDPIEARALG
Mvan_3128|M.vanbaalenii_PYR-1       GLMAPNPAAQMAVLRSAYSAAGVEPRDVDYVETHGTGTLLGDPIEARALG
TH_2454|M.thermoresistible__bu      GIMSPNGAAQRDLFRHTCEITGTSPATVDFVEAHGTGTPTGDPVELDALA
MSMEG_6767|M.smegmatis_MC2_155      GITVPNEEAQEAAIRMALQRAGVEPNDVAYVEAHGTGTPVGDPIEMRALA
                                    .:  *.  **      .   :.     :  :*:**.**  ***:*  : .

MAB_0939|M.abscessus_ATCC_1997      AAYGGSRDADRPLLMGSVKSNIGHTESASGAAGLIKVVLSLQNGVLPQSL
MAV_2370|M.avium_104                EVYG----IDGPCALASVKTNFGHAQAASGALGMMKAILALQHGVVPRNL
Rv2931|M.tuberculosis_H37Rv         TVLGRGRPEDSPLLIGSVKTNLGHTEAAAGIAGFIKTVLAVQHGQIPPNQ
Mb2956|M.bovis_AF2122/97            TVLGRGRPEDSPLLIGSVKTNLGHTEAAAGIAGFIKTVLAVQHGQIPPNQ
MLBr_02357|M.leprae_Br4923          AVLGRGRAEDSPLLIGAVKTNLGHLEAAAGIAGFIKTVLAVQRGQIPPNQ
MMAR_1776|M.marinum_M               SVLGRGRPEESPLLIGAVKTNLGHTEAAAGIAGFIKAVLAVQHGRIPPNQ
MUL_2019|M.ulcerans_Agy99           SVLGRGRPEESPLLIGAVKTNLGHTEAAAGIAGFIKAVLAVQHGRIPPNQ
Mflv_3395|M.gilvum_PYR-GCK          SVLGRGRAADAPLLIGAIKSNLGHTEAAAGIAGFAKTVLALQRGRIPANL
Mvan_3128|M.vanbaalenii_PYR-1       TVLGRGRAADAPLLLGAVKSNLGHLEAAAGVAGFIKAVLALQHQQIPANL
TH_2454|M.thermoresistible__bu      AVYGAAHGPDDPCRVGSVKPNTGHLEGGAGVVGLIKAALALQHGVIPPTA
MSMEG_6767|M.smegmatis_MC2_155      GALTTDRDATRPLVIGSVKTNIGHLEAGAGVAGLIKAALIVKHGHIPANL
                                     .         *  :.::*.* ** :..:*  *: *. * ::.  :* . 

MAB_0939|M.abscessus_ATCC_1997      HFDNPSPHIPWESLPVRVVDKAIPWQANG-RPRRAGVSSFGFTGTNAHVL
MAV_2370|M.avium_104                HFTQLPDDLARIDTKLFVPQQTTPWVSNGGHPRRAAVSSYGLSGTNVHAI
Rv2931|M.tuberculosis_H37Rv         HFETANPHIPFTDLRMKVVDTQTEW-PATGHPRRAGVSSFGFGGTNAHVV
Mb2956|M.bovis_AF2122/97            HFETANPHIPFTDLRMKVVDTQTEW-PATGHPRRAGVSSFGFGGTNAHVV
MLBr_02357|M.leprae_Br4923          RFESPNLHIPFAELRMKVVDKHMEW-PDTGHLRRAAVSSFGFGGTNAHVV
MMAR_1776|M.marinum_M               RFESPNPHIAFADLRMKVVDELTDW-PDTGHPRRAGVSSFGFGGTNAHVV
MUL_2019|M.ulcerans_Agy99           RFESPNPHIAFADLRMKVVDELTDW-PDTGHPRRAGVSSFGFGGTNAHVV
Mflv_3395|M.gilvum_PYR-GCK          DYQSPNPHIPFDNLRLKVVDEVTDW-KPVGRPRVAGVSSFGFGGTNAHVV
Mvan_3128|M.vanbaalenii_PYR-1       GYEKPNPHIPFDNLRLKVIAEHTEWPAPAGRPRRAGVSSFGFGGTNAHVV
TH_2454|M.thermoresistible__bu      GIRELTPAVDWATNGLHVPTTVEPFPRRADSPRRAAVCSYGYGGTIAHLL
MSMEG_6767|M.smegmatis_MC2_155      HLKNPTRHVSLTELKLDIPTIGRPF--PECDRRIAGINSFGFGGTNAHVV
                                            :      : :      :       * *.: *:*  ** .* :

MAB_0939|M.abscessus_ATCC_1997      IEEAP-----QPQATPDEDDASTPQSAPVSVLPLSARSPEALAAVAQRYE
MAV_2370|M.avium_104                LEQAP-----EPAPETVAPEGISAESP--LLFPLSSTSADELRRTAGRLA
Rv2931|M.tuberculosis_H37Rv         IEQG------QEVRPAPGQGLSPA----VSTLVVAGKTMQRVSATAGMLA
Mb2956|M.bovis_AF2122/97            IEQG------QEVRPAPGQGLSPA----VSTLVVAGKTMQRVSATAGMLA
MLBr_02357|M.leprae_Br4923          IEQG------PELTPVTECSSNTA----VSTLVVTGKTASRVAAMAGMLA
MMAR_1776|M.marinum_M               IEQG------QEAASSPEAGLTPA----LSTLVVAGKTPARVAATAGMLA
MUL_2019|M.ulcerans_Agy99           IEQG------QEAASSPEADLTPA----LSTLVVAGKTPARVAATAGMLA
Mflv_3395|M.gilvum_PYR-GCK          LEQA------PDPTPAEDTDVAPAAASPVTTLVVAGKSAPRIATTAGMLA
Mvan_3128|M.vanbaalenii_PYR-1       IEQA------PPKAPATNGQGEPA----VTTLVVSGRTAERIASEAGMLA
TH_2454|M.thermoresistible__bu      LEEAPAVDETPAAAPAPAADAADANSPRFHVIPVSARSGARLARHAAALR
MSMEG_6767|M.smegmatis_MC2_155      LAEP----------PAARHSAETGDHRVLTVLPISARSEEALVATAGRLA
                                    : :                            : ::. :   :   *    

MAB_0939|M.abscessus_ATCC_1997      SWLAA--HPDVDLEDVCLTAGRGRSHFEHRAALVVDSIQTAREGLLELAQ
MAV_2370|M.avium_104                DWVHA--HGDLALPDLAYTLARRRVHRPVRTAVLAGDRAQLIEALREVAD
Rv2931|M.tuberculosis_H37Rv         DWMEG-PGADVALADVAHTLNHHRSRQPKFGTVVARDRTQAIAGLRALAA
Mb2956|M.bovis_AF2122/97            DWMEG-PGADVALADVAHTLNHHRSRQPKFGTVVARDRTQAIAGLRALAA
MLBr_02357|M.leprae_Br4923          DWVEG-PGAEVALADVAHTLNHHRSRHAKFGTVVARDRIQAVAGLRALAA
MMAR_1776|M.marinum_M               DWMEG-PGAEVALADVAHTLNHHRSRQARFGTVVARERAQAVAGLRALAA
MUL_2019|M.ulcerans_Agy99           DWMEG-PGAEVALADVAHTLNHHRSRQARFGTVVARERAQAVAGLRALAA
Mflv_3395|M.gilvum_PYR-GCK          EWLAG-DGADVPLDQVAHSLNHHRAQHSKFATVCTRDRAGALAGLQALAA
Mvan_3128|M.vanbaalenii_PYR-1       EWMAGPEGSLASLPEVAHTLNHHRSHYNKFATVAARDRDQAIAGLRALAA
TH_2454|M.thermoresistible__bu      GHLSA----GADLTAVAATMWQRRSHEPVRAAVIARHPGELVAGLDAIAT
MSMEG_6767|M.smegmatis_MC2_155      GHLAA--HPEVTLADLGYTLSHRRAHLNHRHTFVVDSIDEARRQLQAVAD
                                      : .       *  :  :  : * :     :. .         *  :* 

MAB_0939|M.abscessus_ATCC_1997      NRLRPGVVR--GEHTNHPTTAWLFTGQGSQYPGMARELFDAEPVFAETVT
MAV_2370|M.avium_104                GDTPYPAAV--GRGDRGP--VWVFSGQGSQWAAMGADLLATEPVFAATVA
Rv2931|M.tuberculosis_H37Rv         GQHAPGVVN-PADGSPGPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVA
Mb2956|M.bovis_AF2122/97            GQHAPGVVN-PAEGSPGPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVA
MLBr_02357|M.leprae_Br4923          GKQAPGVVG-QQDGTPGSGTVFVYSGRGSQWAGMGRQLLADEPAFTAAVA
MMAR_1776|M.marinum_M               NQHAPGVVN-PADAPPEPGTVFVYSGRGSQWAGMGRQLLADEPVFAAAVA
MUL_2019|M.ulcerans_Agy99           NQHAPGVVN-PADAPPEPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVA
Mflv_3395|M.gilvum_PYR-GCK          GHTAPGVVP-PHQGSCRPGKVFVYSGQGAQWTGMGRRLLADEPAFAAAVA
Mvan_3128|M.vanbaalenii_PYR-1       GQTAPGVVG-APTGARKRGTVFVYSGQGSQWPGMARQLLADEPAFANALA
TH_2454|M.thermoresistible__bu      DTRHPAVVAGSVLPAAEAGAVWVFSGHGSHWPGMGRELLEHEPVFAAVID
MSMEG_6767|M.smegmatis_MC2_155      GGQIS------AGRAGEARLAFVCTGMGPQWWQMCRGLLDVFPVFTDSIH
                                    .                   .:: :* *.::  *   *:   *.*:  : 

MAB_0939|M.abscessus_ATCC_1997      RCAEAVKDIVTRPLLEVMFATDRETGGKAGEALRHTSFAQPALFAVEMGL
MAV_2370|M.avium_104                QAEPLIARESGFSVAEAMSAPQTVTGQDR---------VQPTLFTMQVAL
Rv2931|M.tuberculosis_H37Rv         ELEPVFVEQAGFSLHDVLANGEELVGIEQ---------IQLGLIGMQLAL
Mb2956|M.bovis_AF2122/97            ELEPVFVEQAGFSLHDVLANGEELVGIEQ---------IQLGLIGMQLAL
MLBr_02357|M.leprae_Br4923          ELEPVFVVHAGFSLHDVLANGKELVGIEQ---------IQLGLIGMQLTL
MMAR_1776|M.marinum_M               ELEPVFLAEAGFSLHDVLANGTELVGIEQ---------IQLGLIGMQLTL
MUL_2019|M.ulcerans_Agy99           ELEPVFLAEAGFSLHDVLANGTELVGIEQ---------IQLGLIGMQLTL
Mflv_3395|M.gilvum_PYR-GCK          ELEPVFVEQVGFSLQQILAGGETVTGIDR---------IQPVLVGMQLAL
Mvan_3128|M.vanbaalenii_PYR-1       EIEPVFVEQVGFSLRDVIAGGETVSGDAQ---------VQPVLMGLQLAL
TH_2454|M.thermoresistible__bu      EIEPVFRAELGFSPRQALQSGE-LGGTDR---------VQALTFAVQAGL
MSMEG_6767|M.smegmatis_MC2_155      RTDRELSRYADWSLLEELTRDEASSRMGET------EFAQPANFAIQVAL
                                    .    .      .  : :                     *   . ::  *

MAB_0939|M.abscessus_ATCC_1997      ARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSIEDGARLIAERGRLFGGL
MAV_2370|M.avium_104                AATMKAHGVRPGAVIGHSLGEAAAAVVAGALSLEDGARVICRRSRLMSRV
Rv2931|M.tuberculosis_H37Rv         TELWCSYGVRPDLVIGHSMGEVAAAVVAGALTPAEGLRVTATRSRLMAPL
Mb2956|M.bovis_AF2122/97            TELWCSYGVQPDLVIGHSMGEVAAAVVAGALTPAEGLRVTATRSRLMAPL
MLBr_02357|M.leprae_Br4923          TELWRSYGVQPDLVIGHSLGEVAAAVVAGALTAAEGLRVTATRSRLMAPL
MMAR_1776|M.marinum_M               TELWRSYGIQPDLVIGHSMGEVAAAVVAGALTPAEGLRVTAVRSRLMAPL
MUL_2019|M.ulcerans_Agy99           TELWRSYGIQPDLVIGHSMGEVAAAVVAGALTPAEGLRVTAVRSRLMAPL
Mflv_3395|M.gilvum_PYR-GCK          TELWRAYGVHPDAVIGHSMGEVAASVVAGALSVADGLKVIATRSKLMSRL
Mvan_3128|M.vanbaalenii_PYR-1       TELWRSYDVHPDAVIGHSMGEVTAAVVAGALSLADGLKVIAARSSIMSRL
TH_2454|M.thermoresistible__bu      AAVLRDRGVKPAAVIGHSVGEVAACVAAGVFDLARGAAVACYRARGFRSV
MSMEG_6767|M.smegmatis_MC2_155      AEQLAHFGITPDAVIGHSAGEVAAHHIAGLLTFEQAVHVIYHRSRLQQRT
                                    :      .: *  *:*** *: :*   ** :    .  :   *.      

MAB_0939|M.abscessus_ATCC_1997      PAGGR--MVAVFSDAKHVEQIAGEFP------RVSVGAYNGP-NTVLSGP
MAV_2370|M.avium_104                AGTGATASVELPAQQVLSELTARGIS------DVVVAVVASPQSTVIAGA
Rv2931|M.tuberculosis_H37Rv         SGQGG--MALLELDAPTTEALIADFP------QVTLGIYNSPRQTVIAGP
Mb2956|M.bovis_AF2122/97            SGQGG--MALLELDAPTTEALIADFP------QVTLGIYNSPRQTVIAGP
MLBr_02357|M.leprae_Br4923          SGQGG--MALLELDAVETEALIVDYS------QVTLAIYNSPRQTVIAGP
MMAR_1776|M.marinum_M               SGQGG--MALLELDASQTEALIADYP------QVTLGIYNSPRQTVISGP
MUL_2019|M.ulcerans_Agy99           SGQGG--MALLGLDASQTEALIADYP------QVTLGIYNSPRQTVISGP
Mflv_3395|M.gilvum_PYR-GCK          SGQGA--MALIELDPDAATALIADYP------DVTLAVYASPRQTVIAGP
Mvan_3128|M.vanbaalenii_PYR-1       AGQGA--VALVELDPEAAAAFIADYP------SVEVAGFVSPRQTVVAGL
TH_2454|M.thermoresistible__bu      AGKGA--MALVGLPFEDARQRLGERT------DVVAAISASPLSTVISGT
MSMEG_6767|M.smegmatis_MC2_155      TGQGR--MLAVGLDAETLMQILDEKILDQFGRRVSVAAINSPSAVTVAGD
                                    .. *      :                      *  .   .*  ..::* 

MAB_0939|M.abscessus_ATCC_1997      GEDLEQAVARFQEEGIRCTWLETSHAFHSELLDPILDEFESYAAQVQFAA
MAV_2370|M.avium_104                APTVRDLVTAWQERGVMAREVPTDVAFHSPQVDPIMDDLTDALAEISPRP
Rv2931|M.tuberculosis_H37Rv         TEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRT
Mb2956|M.bovis_AF2122/97            TEQIDELITRVRARDRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRT
MLBr_02357|M.leprae_Br4923          TEQIDELIDRVRAQNRFASRVNIEVAPHNPAMDALQPQMRSELADVAPRT
MMAR_1776|M.marinum_M               TDQIDELITVVRARDRFATRVNIEVAPHNPAMDALQPQMRSELADLAPRT
MUL_2019|M.ulcerans_Agy99           TDQIDELITVVRARDRFATRVNIEVAPHNPAMDALQPQMRSELADLAPRT
Mflv_3395|M.gilvum_PYR-GCK          PDQVDAVIAAVSAQDRLARRIEVDVASHHPTIDPILPELREALSGLRPVS
Mvan_3128|M.vanbaalenii_PYR-1       PEQVDAVIAAVTAQEKFARRVNMEVASHTALMDPVLPDLREALAGVTPRT
TH_2454|M.thermoresistible__bu      VDAVGEVSAAWAEQGVMVRKVNTDVAFHSPAMDALTAELARLTSTLTPKP
MSMEG_6767|M.smegmatis_MC2_155      ADVLEDIARHLDEAQIFNRYLAVKVPYHTHYMETIKDDLHTAFASLSSKA
                                       :                :  . . *   ::.:   :    : :   .

MAB_0939|M.abscessus_ATCC_1997      PTLPLVCNRTGAVLTAQ---TPIDGQYWRRHSRQPVQFAESVRTVAALG-
MAV_2370|M.avium_104                PEVPYYS-ATLFDPREQ---PVCDARYWANNMRRMVRFATAVQAALEDG-
Rv2931|M.tuberculosis_H37Rv         PTIGIISTTYADLHTQ----PVFDAEHWATNMRNPVRFQQAIASAGSGAD
Mb2956|M.bovis_AF2122/97            PTIGIISTTYADLHTQ----PVFDAEHWATNMRNPVHFQQAIASAGSGAD
MLBr_02357|M.leprae_Br4923          PTIPILSTTYADLGSC----PVFDAQHWATNMRNPVHFQQAIMTAGT---
MMAR_1776|M.marinum_M               PTIPIISTTYADLGSARESGPTFDAEHWAINMRNPVHFQQAITAAAT---
MUL_2019|M.ulcerans_Agy99           PTIPIISTTYADLGAARESGPTFDAEHWAINMRNPVHFQQAITAAAT---
Mflv_3395|M.gilvum_PYR-GCK          PNIPIVITTREHDGPE----PVFDADYWVDNLRNPVRFEQAVAAAGA---
Mvan_3128|M.vanbaalenii_PYR-1       PNIPFLSTVTEPDG-E----PALDADYWVANVRQPVKFSQAVTAAAQ---
TH_2454|M.thermoresistible__bu      AAVPLYSTALADPRST----AARDEHYWVANLRGRVRFAEAVTAAAED--
MSMEG_6767|M.smegmatis_MC2_155      ATLPLYSTVTGELLDR----YDAGAAYWWQNTRATVLFEPAMRRMLDDG-
                                    . :                    .  :*  : *  * *  ::        

MAB_0939|M.abscessus_ATCC_1997      --CSVLMEIGPQPVLTGAAVQVWPEH--LAPPRAIVSLRKG--------V
MAV_2370|M.avium_104                --YRVFAELAPHPLLVRALEQTARSR--EIPMAALAGMRRG--------Q
Rv2931|M.tuberculosis_H37Rv         GAYHTFIEISAHPLLTQAIIDTLHSAQPGARYTSLGTLQRD--------T
Mb2956|M.bovis_AF2122/97            GAYHTFIEISAHPLLTQAIIDTLHSAQPGARYTSLGTLQRD--------T
MLBr_02357|M.leprae_Br4923          -DHRTFIEISAHPLLTQAITDTLH----GTRCISIGTLQRD--------A
MMAR_1776|M.marinum_M               -DKHNFIEISAHPLLTQAILETLHTVQPGSKYTSLGTLQRD--------S
MUL_2019|M.ulcerans_Agy99           -DKHNFIEISAHPLLTQAILETLHTVQPGSKYTSLGTLQRD--------S
Mflv_3395|M.gilvum_PYR-GCK          -EIGTFIEVSPHPLLTYGISDTLG----TSHHHSVPTLLRETGSEGDEAS
Mvan_3128|M.vanbaalenii_PYR-1       -EIGTFIEVSANPILTYAINDTLS----SASHVSLGTLARD--------A
TH_2454|M.thermoresistible__bu      -GHRLFLEVSAHPVVCHSMAETLALA-EVGEHAVLPVLRRE--------Q
MSMEG_6767|M.smegmatis_MC2_155      --YTHFVELGPHPVLAASILESAG----TQRVSVDASQRRG--------Q
                                         : *:..:*::  .  :                  :          

MAB_0939|M.abscessus_ATCC_1997      EDRRQIADALASAYVSGHRPNFAALQRHP-RRTVELPTYPFQRRRFWPKS
MAV_2370|M.avium_104                ALPHGLRGFVADLHNAGAAVDFSVLYPTG--RLVDAPLPTWTHRRLWLTD
Rv2931|M.tuberculosis_H37Rv         DDVVTFRTNLNKAHTIHPPHTPHPPE-----PHPPIPTTPWQHTRHWITT
Mb2956|M.bovis_AF2122/97            DDVVTFRTNLNKAHTIHPPHTPHPPE-----PHPPIPTTPWQHTRHWITT
MLBr_02357|M.leprae_Br4923          DDTVTFHTNLNNVHTVHPPHTPHPAE-----PHVTIPSTPWQHTRHWIPR
MMAR_1776|M.marinum_M               DDTIVFRTNLNTVRTA-PPQTPHPPE-----PHPQIPTTPWHHTHHWIDT
MUL_2019|M.ulcerans_Agy99           DDTIVFRTNLDTVRTA-PPQTPHPPE-----PHPQIPTTPWHHTHHWIDT
Mflv_3395|M.gilvum_PYR-GCK          DETLSFHTNLNSTFTTKPPVSDHGPE-----PHPVLPATPWHHTRHWVAH
Mvan_3128|M.vanbaalenii_PYR-1       DDTLTFHTALNATFTGHPPVTPHHGE-----PHIQLPTTPWHHTHHWAIR
TH_2454|M.thermoresistible__bu      PELPAVAAVVGALYCHGAPVRPAFPPGTR--WATGLPGTQWQHRRFWRTP
MSMEG_6767|M.smegmatis_MC2_155      DDARTLLNCVGALHSRGHEVAWDMVQPRAGAHPVKLPSYPWQTKRFWNDT
                                         .   :                          *   :   : *   

MAB_0939|M.abscessus_ATCC_1997      --SGTAIEGGGGLPSGILGRG-----EDLASGDSVYISRLSVRSQPWLSD
MAV_2370|M.avium_104                --GGLESPTHGGCTVAVHPLLGPHVHLQEEPERHLWQADVGTAAQPWLAD
Rv2931|M.tuberculosis_H37Rv         -KYPAGSVGSAPRAGTLLGQHTTVATVSASPPSHLWQARLAPDAKPYQGG
Mb2956|M.bovis_AF2122/97            -KYPAGSVGSAPRAGTLLGQHTTVATVSASPPSHLWQARLAPDAKPYQGG
MLBr_02357|M.leprae_Br4923          -KRSVNSIGLAPQVGTLLGQHT---AVSGILPIHLWQARLAPQAKPYRGW
MMAR_1776|M.marinum_M               -PAVASRSASTPDKD----------AAGSSEPSVSGDSDDAVDSCHYR--
MUL_2019|M.ulcerans_Agy99           -PAVASRSASTPDKD----------AAGSSEPSVSGDSDDAVDSCHYR--
Mflv_3395|M.gilvum_PYR-GCK          -KKVDRRGPSAPRPGTLLGDLT---SVATSPPTHLWQARLVRDAKPYPGF
Mvan_3128|M.vanbaalenii_PYR-1       -KHTAS-GATAPRPGTVLGSHT---AVAGTQPGHLWQARLAPQAKPYPQP
TH_2454|M.thermoresistible__bu      GTPPGGVGVHDVDSHTLLGGR---IDVAGAVPARVWQTRLDLSTRPYPGD
MSMEG_6767|M.smegmatis_MC2_155      ---------HEAEEALFYRPVHPLLGQPVRAVHPTWEAEFSTLTVPFLAD
                                                                         :     :  :   

MAB_0939|M.abscessus_ATCC_1997      HVIYGTVVVPGATYAAMALAAVG----TPARAKDVFFYEPIILPEKSSRE
MAV_2370|M.avium_104                HQIRNVVVLPGAAYCEMALAAARSVLGATAEVRDIRFEQALLLDEQTTVD
Rv2931|M.tuberculosis_H37Rv         HRFHQVEVVPASVVLHTILSAATEL--GYSALSEVRFEQPIFADRPRLIQ
Mb2956|M.bovis_AF2122/97            HRFHQVEVVPASVVLHTILSAATEL--GYSALSEVRFEQPIFADRPRLIQ
MLBr_02357|M.leprae_Br4923          HRVHGVEVVPASIVLRTILCAAAEL--GYSTLFEIRFEQPIFANLPRLIQ
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          HRIQGVEVVPMSVLLRTLAAAAAES--GASALADIRFDRPVVVDQPQVIQ
Mvan_3128|M.vanbaalenii_PYR-1       HKFAGVEIVPLSVLLQTLSLAAAES--GARAVADVRFDFPITVDAPRVVQ
TH_2454|M.thermoresistible__bu      HPVQGTEIVPAAVLLNTFLTAAG------SDIADVRLRTPVAPARTRDVQ
MSMEG_6767|M.smegmatis_MC2_155      HQVQGSVVVPGAVYVEMALAAGRETYGSDLSVDNLVLHRAVILDDTCDPV
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      VQLTLHPLEDGSGSKFQVHSRPYGE-----------------------RD
MAV_2370|M.avium_104                ASASVSSP---GVLHFTVQSHQGGE-----------------------QA
Rv2931|M.tuberculosis_H37Rv         VVADNRAISLAS---SPAAGTPSDR-------------------------
Mb2956|M.bovis_AF2122/97            VVADNRAISLAS---SPAAGTPSDR-------------------------
MLBr_02357|M.leprae_Br4923          VVVDNQLISLAS---SPATETPQHR-------------------------
MMAR_1776|M.marinum_M               VGWPTKPLADAK---ASTETASGTR-------------------------
MUL_2019|M.ulcerans_Agy99           VGWPTKPLADAK---ASTETASGTR-------------------------
Mflv_3395|M.gilvum_PYR-GCK          VVAHGDTITMAS---APHADAPANR-------------------------
Mvan_3128|M.vanbaalenii_PYR-1       VVSDGETITVSSSTAAAGSDDSAQR-------------------------
TH_2454|M.thermoresistible__bu      VVLQDRALALASRIVGEDTTARATAGRDTTDRDTTACDTTDRDTTACDDP
MSMEG_6767|M.smegmatis_MC2_155      IRTTVDQDDGSVEFAALIATADTDLK------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      VDWSLNAEGTVVTGIGDDAEPAPEAAEPAEPVDAAIERMERMRPMELFEI
MAV_2370|M.avium_104                RHASAVLGAATDEQPAAHDLSALLTAHPHDDDGDEVRRRMDRRGVQYGPA
Rv2931|M.tuberculosis_H37Rv         --WTRHVTAQLSSSPSDSASSLNEHHRANGQPPERAHRDLIPDLAELLAM
Mb2956|M.bovis_AF2122/97            --WTRHVTAQLSSSPSDSASSLNEHHRANGQPPERAHRDLIPDLAELLAM
MLBr_02357|M.leprae_Br4923          --WTRHVTAQLSSASARSAVPSDHPDQING--HLEVISDPIPDVASLLAL
MMAR_1776|M.marinum_M               --WLVFADAELGAELGLAAG------------------------------
MUL_2019|M.ulcerans_Agy99           --WLVFADAELGAELGLAAG------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --WVRHATARVAQPRPADTGAVDVTAATD---------YDRSTVEELQSR
Mvan_3128|M.vanbaalenii_PYR-1       --WIRHLTARVAHRVADSPATAGTAQSSG---------YDPSALAELHNA
TH_2454|M.thermoresistible__bu      GVWLTHCTARVADDHVGAEGVLDEEAIRAR----CPQPLPAGHVVDTLAG
MSMEG_6767|M.smegmatis_MC2_155      --WVITATAELNTLPRAPRAGDTGGGAVTSTDGDTFYQRTQALGFDYGEA
                                            .                                         

MAB_0939|M.abscessus_ATCC_1997      FADLELAWGPTWSGSLKSLWLGEGEAIGDVLVGEELAEQLGTEPMHPVLM
MAV_2370|M.avium_104                FAGLGAVHSGDETG----------TVLAEVALPRQIRSQQAAYGAHPALL
Rv2931|M.tuberculosis_H37Rv         RGIDGLPFSWTVASWT-----------------QHSSNLTVAIDLPEALP
Mb2956|M.bovis_AF2122/97            RGIDGLPFSWTVASWT-----------------QHSSNLTVAIDLPEALP
MLBr_02357|M.leprae_Br4923          CGVDGLPFEWSVKSWAKK--------------TQQSTSRTVEIEFPDTLP
MMAR_1776|M.marinum_M               ------------------------------------AQTRVDVIDPSALT
MUL_2019|M.ulcerans_Agy99           ------------------------------------AQTRVDVIDPSALT
Mflv_3395|M.gilvum_PYR-GCK          WGVEGQPFPWSIET---------------------CRATSDGVLAEVRWQ
Mvan_3128|M.vanbaalenii_PYR-1       WGIDGMAYPWTVAS---------------------HESAPGELRTVIDLT
TH_2454|M.thermoresistible__bu      LGVAAMGFGWEVLELHR----------------GEGELFARVAAEPDKSA
MSMEG_6767|M.smegmatis_MC2_155      FRSVASVTAGRDWAVAQIDIP------------QSISADVDTYRFHPALI
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      DLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLKEKMPRRFYCRARWH
MAV_2370|M.avium_104                DACF-QSVEAHPAVRALGDGALGLVLGIRR----LRAYGAARNAHYCYTR
Rv2931|M.tuberculosis_H37Rv         EGSTGPLLDAAVHLAALSDVADSRLYVPASIEQISLGDVVTGPRSSVTLN
Mb2956|M.bovis_AF2122/97            EGSTGPLLDAAVHLAALSDVADSRLYVPASIEQISLGDVVTGPRSSVTLN
MLBr_02357|M.leprae_Br4923          DGAIAPLLDAAILIPALADVTETQFYVPASIKQVWLGDTATGPCGAVTLN
MMAR_1776|M.marinum_M               EESE--------LLAALAGVEH----------------------------
MUL_2019|M.ulcerans_Agy99           EGSE--------LLAALAGVEH----------------------------
Mflv_3395|M.gilvum_PYR-GCK          DGSAVALLDAAVQVARLADINDDRLLVPAAVESLTATGELLASSGTVTVR
Mvan_3128|M.vanbaalenii_PYR-1       PGSLVGLLDAAVNLGRLVDSSSPGLMVPSAAESVRFGDDATGTGGVITAR
TH_2454|M.thermoresistible__bu      PATWAGLIDAATSTASTIFDGPPRLRMPARIERVHVRDKPP----AIALL
MSMEG_6767|M.smegmatis_MC2_155      DGAFQTLFG-----APFSGQEENTDPYLPTRIRHCAVYGPPAEHMTVRAR
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      ESPLDSETQVFDLDYLDRDGRHLGGIREFTVKRAPREA-----------L
MAV_2370|M.avium_104                VTKADTSGVEADIDVLDEHGAVLLAVQGLRVGTSASES-----------G
Rv2931|M.tuberculosis_H37Rv         RTAHDDDGITVDVTVAAHGEVPSLSMRSLRYRALDFGLDVGRAQPPASTG
Mb2956|M.bovis_AF2122/97            RTAHDDDGITVDVTVAAHGEVPSLSMRSLRYRALDFGLDVGRAQPPASTG
MLBr_02357|M.leprae_Br4923          RTACDDDGITVDVTVADGSGVPLALMRSLRYRALDLDNAQQDYSTVFVES
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          RRPGTGEDLVLDVAVTVPDDSTRVDIVGLRYVDVQAG------------P
Mvan_3128|M.vanbaalenii_PYR-1       SRGRDGDDLLVDISIGGAGGAEYAHITGLRYTPVEIGT-----------V
TH_2454|M.thermoresistible__bu      HVRRRPEGTVTDVTIAEESGAVSVTLTGMGFEELENP------------G
MSMEG_6767|M.smegmatis_MC2_155      VLSATHDAVECDITITDPSGGVLAAFDGFTVQSLSASS------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      LRGLGGDATRLLYTLGWHEVAVPPVAGEG----EESAASIGTWLIAGFDE
MAV_2370|M.avium_104                TRDRVLTERLLNIEWRQRELPEPEHADAASWLLIGTTATADVLASTLADT
Rv2931|M.tuberculosis_H37Rv         PVEAYCDATNFVHTIDWQPQTVPDATHPGAEQVTHPGPVAIIGDDGAALC
Mb2956|M.bovis_AF2122/97            PVEAYCDATNFVHTIDWQPQTVPDATHPGAEQVTHPGPVAIIGDDGAALC
MLBr_02357|M.leprae_Br4923          HVDALTDARNFVHAIDWQPRTDLDCSN---TPVASSGSVAVIGDARAGFG
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          AEAAPADPRSVAHEIAWRPWTAPSETAPAGASLAVVGS--------GTTA
Mvan_3128|M.vanbaalenii_PYR-1       TTSAAADPQRVAHRLDWQPWTPAADAGPDTGSVAVIGD--------DDVA
TH_2454|M.thermoresistible__bu      GGGSSGDLTGMLHHLRWHPVDWPDTDPPAAVVLVG-----------GDAR
MSMEG_6767|M.smegmatis_MC2_155      -RMSADHIDKGLFALEWSPVTDTPDTAHGDESTWLILTDNGGVGEAIADG
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      LAAKVPGCIPLNRETDPELLGEVLVAAKERGVPFSGVVWRAAGPGATEST
MAV_2370|M.avium_104                LKNHGAQCTTMAWPQQADHTAHAEQLRNQWRGDGFTGVVVLTGPKNGDND
Rv2931|M.tuberculosis_H37Rv         ETLEGAGYQPAVMSDGVSQARYVVYVADS------------DPAGADETD
Mb2956|M.bovis_AF2122/97            ETLEGAGYQPAVMSDGVSQARYVVYVADS------------DPAGADETD
MLBr_02357|M.leprae_Br4923          LLLKEAGYTLAAPADGVSEVRYVVYVADP------------HPATTAETD
MMAR_1776|M.marinum_M               ----------------------VVYAP---------------PAG-KSLD
MUL_2019|M.ulcerans_Agy99           ----------------------VVYAP---------------PAG-KSLD
Mflv_3395|M.gilvum_PYR-GCK          DALRERLAAAGYTDADEATAQCVLYVP-----------------GPDGDD
Mvan_3128|M.vanbaalenii_PYR-1       AAVRGAVAANGHAVAEIPDARFVVYVAD---------------VGDVDSD
TH_2454|M.thermoresistible__bu      TRAFVTRDLDEARVAHRSYADPAALPPDL------------TAGTVVLVL
MSMEG_6767|M.smegmatis_MC2_155      LRLRGHHVHTVAHDPTGEIDWPDMLATHLSGE-------RTGLIDCWPLE
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      TESAARLEGEIAHLLSAVHTVQNSAQNGVKLPGGLWIVTERAVATESGEP
MAV_2370|M.avium_104                QESALLSRDHVQHLVRIARELTDLPGE----PPRLYVVTRNAQTVLPNDV
Rv2931|M.tuberculosis_H37Rv         VDFAVRICTEITGLVRTLAERDADKPAA------LWILTRGVHESVAP--
Mb2956|M.bovis_AF2122/97            VDFAVRICTEITGLVRTLAERDADKPAA------LWILTRGVHESVAP--
MLBr_02357|M.leprae_Br4923          VDFAVRITAEISDLVRALAKREPGKPVA------LWIVTRGVYESVAS--
MMAR_1776|M.marinum_M               VNAAYQLFHQVRRLVTVMTK--ASLTAK------LLLVTRNAQPIAEGDR
MUL_2019|M.ulcerans_Agy99           VNAAYQLFHQVRRLVAVMTK--ASLTAK------LLLVTRNAQPIAEGDR
Mflv_3395|M.gilvum_PYR-GCK          LDATVRLCGEVASLVSRLADRPGTGEPR------LWILTEGVRDADSA--
Mvan_3128|M.vanbaalenii_PYR-1       QDVAVRLTTEVADLVGTLAERDPRNPAT------LWIVTRGVYESATA--
TH_2454|M.thermoresistible__bu      PRTAARPAASAQLVLHTLQRLSATNSGAR-----LWVLTRGVHEGTDP--
MSMEG_6767|M.smegmatis_MC2_155      VTDAATDPAGTATVLRIVKALATLDGVTP----RLYLVTANAQPAAGTEL
                                       :         ::                   * ::*  .        

MAB_0939|M.abscessus_ATCC_1997      -----VDPVQAALWGFGRTTINEEP-ALRAKLVDGDGSP---------EA
MAV_2370|M.avium_104                -----PNLGQAGLRGLVRVIGMEHP-QLGAGQIDVDES----------TD
Rv2931|M.tuberculosis_H37Rv         -----SALRQSFLWGLAGVIAAEHP-ELWGGLVDLAIN-------DDLGE
Mb2956|M.bovis_AF2122/97            -----SALRQSFLWGLAGVIAAEHP-ELWGGLVDLAIN-------DDLGE
MLBr_02357|M.leprae_Br4923          -----SALRQSFLWGFGGVIAAEHP-EMWGGLVDLAASALGADRDDILDQ
MMAR_1776|M.marinum_M               -----ANPAHGVLWGLGRTIALEHP-EIWRGIIDLDES------MPAELA
MUL_2019|M.ulcerans_Agy99           -----ANPAHGVLWGLGRTIALEHP-EIWRGIIDLDES------MPAELA
Mflv_3395|M.gilvum_PYR-GCK          -----QSLPHSSLWGLAGVVGAEQP-QLWGGLVDVASG-------ADLDE
Mvan_3128|M.vanbaalenii_PYR-1       -----AALPQSTLWGLAGVVGAEQP-QLWGGLVDLAG--------EDPAG
TH_2454|M.thermoresistible__bu      --------GHGPLWGLARVAAAEHP-QLWGGLLDIGED------------
MSMEG_6767|M.smegmatis_MC2_155      TGTELTGVEQAAFWGLGRVIGHQELGEYWGGLIDIDHADAP------SST
                                             :. : *:  .   :.        :*                

MAB_0939|M.abscessus_ATCC_1997      VQALARLLVTPVDEPEIAVRQ-----GKLLASRLLPWSRTGHLTVPRGSD
MAV_2370|M.avium_104                AQALARQLLAGSEEDETAWRDGAWYTARLCPAPLLPEERHTAVANHECDG
Rv2931|M.tuberculosis_H37Rv         FGPALAELLAKPSKSILVRRDG----------------------------
Mb2956|M.bovis_AF2122/97            FGPALAELLAKPSKSILVRRDG----------------------------
MLBr_02357|M.leprae_Br4923          FGPTLASLLQTPTRSIVVLRDG----------------------------
MMAR_1776|M.marinum_M               APKILGEVTGTDGEDQVVYRCG----------------------------
MUL_2019|M.ulcerans_Agy99           APKILGEVTGTDGEDQVVYRCG----------------------------
Mflv_3395|M.gilvum_PYR-GCK          TAKALAGVLPVAAKSILSLRGG----------------------------
Mvan_3128|M.vanbaalenii_PYR-1       SAEALAALLPTPVKSVAILRDG----------------------------
TH_2454|M.thermoresistible__bu      -RLPVRALTALTGHGVVVVRDG----------------------------
MSMEG_6767|M.smegmatis_MC2_155      AEQICGHVLGDGAEDQIALRGN----------------------------
                                           :     .     *                              

MAB_0939|M.abscessus_ATCC_1997      YVLAPTERGAIDNLRITEKEVPAPDEGYVQVRVEAAGLNFRDVLNVLGLY
MAV_2370|M.avium_104                MRLQIRTPGDLESLELVACDRIPPGPGQIEVAVSASSINFADVLVAFGRY
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      PGDPG---PIGGDFAGIVTQLGEGVTGVEVGQRVYG-SMQGAFGSRFNVP
MAV_2370|M.avium_104                PAFEGRLPELGTDFAGVVTAVGPDVTDHKVGDHVGGLSANGCWGTFLTCD
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      AQFLAPIPDGISGVEAATIPAAALTVRL-SFDWAQLKPGDKVLIHAASGG
MAV_2370|M.avium_104                ARLAVTLPPGLADDQAAAVTTAHATAYYGLHELARIGAGDRVLIHSATGG
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      VGLAAIQMAQQFGAEVFATASTFKR-ATLRKLGVKYVYDSRTTDFADQIL
MAV_2370|M.avium_104                VGQAAIAIARAAGAEIFATAGSEQRRQLLRDMGIEHVYDSRTVEFADLIR
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      ADTDGAGVDVVLNSLTSEGFIEATLRATAKNGRFAEIAKRDIWTTEQMAQ
MAV_2370|M.avium_104                HDTDGYGVDIVLNSVTGAAQRAG-IELLAFGGRFVEIGKRDIYGDTRLGL
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      S--RPDIAYEIVALDTVMFQEPDRIRVLLTEVSEGLAKGEWTPLPAEIYP
MAV_2370|M.avium_104                LPFRRNLTFYALDLALMSFSHPDRLRGLLRTVYRLTADGALPMPESTHYP
Rv2931|M.tuberculosis_H37Rv         --------------------------------------------------
Mb2956|M.bovis_AF2122/97            --------------------------------------------------
MLBr_02357|M.leprae_Br4923          --------------------------------------------------
MMAR_1776|M.marinum_M               --------------------------------------------------
MUL_2019|M.ulcerans_Agy99           --------------------------------------------------
Mflv_3395|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6767|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      LTEARTAFRRMQQARHIGKIVCQMPNP------------LAPRPDRTYLI
MAV_2370|M.avium_104                LADAASAIRVMSAAQHTGKLVLDVPHAGRSRVVVPPAQVRAFRSDGAYIV
Rv2931|M.tuberculosis_H37Rv         -------------VVLAPALAPVRGEP--------ARKSLQCRPDAAYLI
Mb2956|M.bovis_AF2122/97            -------------VVLAPALAPVRGEP--------ARKSLQCRPDAAYLI
MLBr_02357|M.leprae_Br4923          -------------VVLAPTLVPIRSEP--------VRKSLQCKSDGAYLI
MMAR_1776|M.marinum_M               -------------GRHVPRLQ-RRTAP--------AVAPVTLDPNSSQLV
MUL_2019|M.ulcerans_Agy99           -------------SRHVPRLQ-RRTAP--------AVAPVTLDPNSSQLV
Mflv_3395|M.gilvum_PYR-GCK          -------------EFFAPELAALASDP--------VREPLRCRPDAAYLI
Mvan_3128|M.vanbaalenii_PYR-1       -------------QLRTSVLAEFTEAP--------ARETLRCRPDAAYLI
TH_2454|M.thermoresistible__bu      -------------VAHTARLAPAGPGARDS-----AGEGLRCSPGGTYLI
MSMEG_6767|M.smegmatis_MC2_155      -------------QILAPRLRPCSGLT--------KPFPTKLTADATYVV
                                                       :      .                .. : ::

MAB_0939|M.abscessus_ATCC_1997      TGGLGAIGLHTAAYLAQLG----AGDIVLTSRRAP--------------D
MAV_2370|M.avium_104                TGGLGGLGLFLAEKMASPGSRAGCGRIVLCSRALP--------------N
Rv2931|M.tuberculosis_H37Rv         TGGLGALGLLMADWLADRG----AHRLVLTGRTPLPPRRDWQLDTLDTEL
Mb2956|M.bovis_AF2122/97            TGGLGALGLLMADWLADRG----AHRLVLTGRTPLPPRRDWQLDTLDTEL
MLBr_02357|M.leprae_Br4923          TGGMGALGLLMADWLADRG----ARRLVLMGRTPLPPRRDWELDTLDAGL
MMAR_1776|M.marinum_M               IGATGNIGPYLIRQLAQMG----AKTVVAVSRNPG---------------
MUL_2019|M.ulcerans_Agy99           IGATGNIGPYLIRQLAQMG----AKTVVAVSRNPG---------------
Mflv_3395|M.gilvum_PYR-GCK          TGGLGALGLVTAEWLADRG----ARRVVLAGRTALPPRRRWDDDDLDKDA
Mvan_3128|M.vanbaalenii_PYR-1       TGGMGVLGLLMADWLADRG----ARRVVLAGRTPLPPRRDWDDESIDADT
TH_2454|M.thermoresistible__bu      TGGTGALGLRLAHRLADLG----ARRLVLVSRSGMPARDSWG----RAGD
MSMEG_6767|M.smegmatis_MC2_155      TGGAGALGRVVATYLAERG----ARHITLLGRSPISPRDRWASITEDDAH
                                     *. * :*      :*. *    .  :.  .*                  

MAB_0939|M.abscessus_ATCC_1997      TDAQRVIGEITERSKTRIHVFTADVGAESEVAGLLERIRAELPPLAGVAH
MAV_2370|M.avium_104                PKALATLERIRQMG-ADIVVERGDIAEAGTAQRLLDVATATGLPVRGVLH
Rv2931|M.tuberculosis_H37Rv         RRRIDAIRALEMRGVTVEAVAADVGCREDVQALLAARDRDGAAPIRGIIH
Mb2956|M.bovis_AF2122/97            RRRIDAIRALEMRGVTVEAVAADVGCREDVQALLAARDRDGAAPIRGIIH
MLBr_02357|M.leprae_Br4923          RQKIDAICALEMRGVTVEAVAVDVGHHDDVQALLAKRDRDGAAPIRGIIH
MMAR_1776|M.marinum_M               QRLQELAESLAAEGTNLVIEAADATDEAAMTALFDRFGAD-LPPLEGIYL
MUL_2019|M.ulcerans_Agy99           QRLQELAESLAAEGTNLVIEAADATDEAAMTALFDRFGAD-LPPLDGIYL
Mflv_3395|M.gilvum_PYR-GCK          RDKIAAVRALELRGVAVELAPVDIGSRDAVEALLTRRDEQGAPPIRGVIH
Mvan_3128|M.vanbaalenii_PYR-1       RHKIAAIRALELRGVSVDTVALDVGSREALTAVLDKRDGDGAPPIRGVIH
TH_2454|M.thermoresistible__bu      SDTVAAITALEERGVSVRVAALDIGAPGAAARLR--EVLADLPDVRGVIH
MSMEG_6767|M.smegmatis_MC2_155      HATVDAIRAIERLGAHVSTASVDITDSDQVRAWLREHTGSGGRPVRGIVH
                                             :   .                              : *:  

MAB_0939|M.abscessus_ATCC_1997      LAGVLDDALLGQQSVERFRTTLAPKAFGAEYLDRLTKG----DDLDFFIV
MAV_2370|M.avium_104                LAAVIEDATLANITDELIERDWAAKVYGAWNLHCALQESGAEQSLDWFCS
Rv2931|M.tuberculosis_H37Rv         AAGITNDQLVTSMTGDAVRQVMWPKIGGSQVLHDAFPP----GSVDFFYL
Mb2956|M.bovis_AF2122/97            AAGITNDQLVTSMTGDAVRQVMWPKIGGSQVLHDAFPP----GSVDFFYL
MLBr_02357|M.leprae_Br4923          AAGVTNDQLVTNMTDDPVRQVMWPKIAGCQVLHEAFPP----GSVDFFYL
MMAR_1776|M.marinum_M               AAFAGGPVLLNEMTDADVRAMFAPKLDAAALLHRLSLK----VPARHFVL
MUL_2019|M.ulcerans_Agy99           AAFAGGPVLLNEMTDADVRAMFAPKLDAAALLHRLSLK----VPARHFVL
Mflv_3395|M.gilvum_PYR-GCK          GAGLTDSQLLTDIDDERLRRTLWPKVAGARVLHELFPT----DSVDFLYL
Mvan_3128|M.vanbaalenii_PYR-1       AAGMTEAQLLTEIEADRVHRTVWPKIAGAKVLDELFPP----GSLDFLYL
TH_2454|M.thermoresistible__bu      AAGVEAGALLTNTTAEDIEATMRPKVDGVLALHEVFPP----GRLDWLVL
MSMEG_6767|M.smegmatis_MC2_155      AAGSVRDQLLVNMGEDDFAEVLAPKITGTRVLHNVFED----HDLEFFVM
                                     *       : .     .     .*  .   *.              :  

MAB_0939|M.abscessus_ATCC_1997      SSSVSSLFGSPGQSNYATANALLDGLIAQRRAQGLPATGINFGPWGQGG-
MAV_2370|M.avium_104                FSSAAALVGSPGQGAYAAANSWLDAFTRWRRARGLKATAIAWGAWAQIG-
Rv2931|M.tuberculosis_H37Rv         TASAAGIFGIPGQGSYAAANSYLDALARARRQQGCHTMSLDWVAWRGLG-
Mb2956|M.bovis_AF2122/97            TASAAGIFGIPGQGSYAAANSYLDALARARRQQGCHTMSLDWVAWRGLG-
MLBr_02357|M.leprae_Br4923          TSSAAGIFGIPGQGSYAAANSYLDALARTRRQQGCHTMSIDWVAWRGLG-
MMAR_1776|M.marinum_M               FSSISGLIGSRWLAHYTATSGYLDALAYARHALGLPATTVNWGLWKSLAD
MUL_2019|M.ulcerans_Agy99           FSSISGLIGSRWLAHYTATSGYLDALAYARHALGLPATTVNWGLWKSLAD
Mflv_3395|M.gilvum_PYR-GCK          TASAGTVFGVPGQGAYAAGNAYLDGLARARRREGGVTASLDWVAWRGLG-
Mvan_3128|M.vanbaalenii_PYR-1       AASAGAVFGIPGQGAYAAGNAYLDALARSRHHRGDNTVSLDWVAWQGLG-
TH_2454|M.thermoresistible__bu      FSSCGYLGGFPGQGAYACGNAYLDAFARYRRASGDATTSVAWTAWRGLG-
MSMEG_6767|M.smegmatis_MC2_155      FGSAGSTIAAPGQGNYAAANAFLDAFAHHRQGLGLPALTIGWGPWSVGM-
                                     .* .   .    . *:  .. **.:   *:  *  :  : :  *     

MAB_0939|M.abscessus_ATCC_1997      ---MASSEAATANISAQGLIPLDPSAALAALAEVVANGTGQATILKANWQ
MAV_2370|M.avium_104                ---RGAALADSADVAIT---PDEGAYAFEALLRHDRACTGYAPITGTPWL
Rv2931|M.tuberculosis_H37Rv         --LAADAQLVSEELARMGSRDITPSEAFTAWEFVDGYDVAQAVVVPMPAP
Mb2956|M.bovis_AF2122/97            --LAADAQLVSEELARMGSRDITPSEAFTAWEFVDGYDVAQAVVVPMPAP
MLBr_02357|M.leprae_Br4923          --FAANAQIVSDELQRMGSRDITPSEAFTAWEYVDAYDVAQAVVLPVPRS
MMAR_1776|M.marinum_M               AEHDASQVSVGSGLLPMQDEVAIGTLPLLMNPAAGVHSVVVEADWPLLAA
MUL_2019|M.ulcerans_Agy99           AEHDASQVSVGSGLLPMQDEVAIGTLPLLMNPAAGVHSVVVEADWPLLAA
Mflv_3395|M.gilvum_PYR-GCK          --FGSDAQVVIDELERQGSRPVTPAEAFAAWEYASRFDVAHVVMAPTLDA
Mvan_3128|M.vanbaalenii_PYR-1       --FGSEAQVVVSELERVGSRPVVPAEAFAAWDFVTRFDVAQVVMAPMQSA
TH_2454|M.thermoresistible__bu      --MGSASDFVAAQLDALGMGTVDVDDAMRALDAAIRDGDPNVVVLPLSPA
MSMEG_6767|M.smegmatis_MC2_155      ----VEELGLEKVYAQRGIELITPAVGARIIDRLLSQSVPAVVAMNADWS
                                                                                      

MAB_0939|M.abscessus_ATCC_1997      RAAKVLGSSRPPILDLVLPSAVGEVTGDSE---LLKQLMEIPVPQRAGFV
MAV_2370|M.avium_104                TAFAQRSP-----FAEAFRANGQSATGTSK---LRAELEELPPEEWSTRL
Rv2931|M.tuberculosis_H37Rv         AGADG----------SGA-NAYLLPARNWS---VMAAT------EVRSEL
Mb2956|M.bovis_AF2122/97            AGADG----------SGA-NAYLLPARNWS---VMAAT------EVRSEL
MLBr_02357|M.leprae_Br4923          YGSAG----------STAGDSYLVPARNWS---QMEAA------EVRKEL
MMAR_1776|M.marinum_M               AYRTRGSLHIVDDLLRDFAEASTIPARDWS---HLSAQ------EVRTEF
MUL_2019|M.ulcerans_Agy99           AYRTRWSLHIVDDLLRDFAEASTIPARDWS---HLSAQ------EVRTEF
Mflv_3395|M.gilvum_PYR-GCK          DEDTD-----------QAAESG--PERDWS---QMSAD------DVVSEL
Mvan_3128|M.vanbaalenii_PYR-1       EDAAA-----------VTADTHRAPTRDWT---AMAPD------ELLAEL
TH_2454|M.thermoresistible__bu      AAAVPMFADVAPADPDADAPGGEVPDGLSD---GFPADGFPDDGDLAEWV
MSMEG_6767|M.smegmatis_MC2_155      RARQVGFGGLVPKMFGELGTADTVGGQDGVGPSILELLAHTADADRPAVI
                                                                                :    .

MAB_0939|M.abscessus_ATCC_1997      TEFLQREVQNFLRLAQPPAATSR-FLDLGTDSLMAIELRNRLHSQFGGKF
MAV_2370|M.avium_104                RRLISDQVSLILRRNVDPDRP---LPEYGLDSLGGLELLTRIQTETG--I
Rv2931|M.tuberculosis_H37Rv         EQGLRRIIAAELRVPEKELDTDRPFAELGLNSLMAMAIRREAEQFVG--I
Mb2956|M.bovis_AF2122/97            EQGLRRIIAAELRVPEKELDTDRPFAELGLNSLMAMAIRREAEQFVG--I
MLBr_02357|M.leprae_Br4923          ESGLRTIIAAELRVAEAELDTDRPFAELGLNSLMAMAIRREAEQFIG--I
MMAR_1776|M.marinum_M               EAGLRRIVARELRVSESDLETDRPLAELGLNSLMAMAIRREAEMFVG--I
MUL_2019|M.ulcerans_Agy99           EAGLRRIVARELRVSESDLETDRPLAELGLNSLMAMAIRREAEMFVG--I
Mflv_3395|M.gilvum_PYR-GCK          ESGLRTILAVELRIGDDEVDSDRPLAEMGLNSVMAMSIRREVEKLAG--I
Mvan_3128|M.vanbaalenii_PYR-1       QDGLRGILATELRLPESDVHTDRPFAEMGLNSVMAMSIRREVERLVG--L
TH_2454|M.thermoresistible__bu      HRRVIAAVAGELGLAETDVDPRLPLVEIGVDSIMTVALRRQLERQTG--L
MSMEG_6767|M.smegmatis_MC2_155      AEQVRRLVAAVFDCAVTDIEPDDMLDDIGLDSMMAMDFRVRINSAFS--I
                                       :   :   :        .   : : * :*:  : :  . .   .  :

MAB_0939|M.abscessus_ATCC_1997      TINATAVFDYPTIGGLAEYLVGQLPDADAESAEAPPAVESAEA-------
MAV_2370|M.avium_104                RVSPADIAAIGTIRGLADLLRDKLTPAGAAQAERV---------------
Rv2931|M.tuberculosis_H37Rv         ELSATMLFNHPTVKSLASYLAKRVAPHDVSQDNQISALSSSAG-------
Mb2956|M.bovis_AF2122/97            ELSATMLFNHPTVKSLASYLAKRVAPHDVSQDNQISALSSSAG-------
MLBr_02357|M.leprae_Br4923          ELSAIMLFNHPTVALLAAYLTKVVAPQHDSQGDEMAALSASAG-------
MMAR_1776|M.marinum_M               ELSATMLFNHPTVASLASYLANRVAPQDNSSNDQMAELSASAG-------
MUL_2019|M.ulcerans_Agy99           ELSATMLFNHPTVASLASYLANRVAPQDNSSNDQMAELSASAG-------
Mflv_3395|M.gilvum_PYR-GCK          ELSATMLWNYPTIGALAAYLAEKVAPQAVA----EAAEEDSGD-------
Mvan_3128|M.vanbaalenii_PYR-1       ELSATMLFNHPTIESFASYLAQQLAPETGGD---DEVADDSGG-------
TH_2454|M.thermoresistible__bu      TLPPTLLWEHPTAGAVSDRIVEMLRARG----------------------
MSMEG_6767|M.smegmatis_MC2_155      DLPVLEILRGVSVNSLSARILAELRDIHGVAPVEPDTGETASEPTTTDDD
                                     :    :    :   .:  :   :                          

MAB_0939|M.abscessus_ATCC_1997      ----------ESGAGPAAASDAVSELKE----
MAV_2370|M.avium_104                --------------------------------
Rv2931|M.tuberculosis_H37Rv         ----------SVLDSLFDRIESAPPEAERSV-
Mb2956|M.bovis_AF2122/97            ----------SVLDSLFDRIESAPPEAERSV-
MLBr_02357|M.leprae_Br4923          ----------GVLDSLFDRIESTSTEAEGLV-
MMAR_1776|M.marinum_M               ----------STLDSLFDRIESSSLLPEGPG-
MUL_2019|M.ulcerans_Agy99           ----------STLDSLFDRIESSSLLPEGPG-
Mflv_3395|M.gilvum_PYR-GCK          ----------SLLDSLFDSVEN----------
Mvan_3128|M.vanbaalenii_PYR-1       ----------SLLDSLFDSVEN----------
TH_2454|M.thermoresistible__bu      --------------------------------
MSMEG_6767|M.smegmatis_MC2_155      VERLLQDLSEAEMRQLLAELEASGTEAGGAIS