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ATSAQVLTVLTRRGLEADLKNGVLSRVWHGIYGRGELTSGLRLRGVDLAVGTPVAACLGTAAAAYGFDTE QTGDLHVLNPEGRQLRSTDGLTVHRRAGAPLTRLAGRELRTPAWTAIEVARGLRRPRALATLDAALRSGT CDRDDLDRAVCLQSGRRGVVAVRELLALASPLAESPMESETRLVMIEGGLPAPVLQYELVGSDGRRWRLD FAWPGLRVAAEYDGVDWHSGPQAFLRDRRRSAALQELGWVIVPIVAGDVRHRPAELVQRLAGALARAQAA *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2670 | - | - | 100% (281) | hypothetical protein MUL_2670 |
| M. ulcerans Agy99 | MUL_1301 | - | 2e-85 | 58.67% (271) | hypothetical protein MUL_1301 |
| M. ulcerans Agy99 | MUL_4737 | - | 6e-24 | 33.78% (225) | hypothetical protein MUL_4737 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2272 | - | 2e-81 | 56.46% (271) | hypothetical protein Mb2272 |
| M. gilvum PYR-GCK | Mflv_4824 | - | 2e-89 | 60.85% (281) | hypothetical protein Mflv_4824 |
| M. tuberculosis H37Rv | Rv2248 | - | 6e-82 | 56.83% (271) | hypothetical protein Rv2248 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3617 | - | 5e-69 | 47.76% (268) | hypothetical protein MAB_3617 |
| M. marinum M | MMAR_1222 | - | 1e-157 | 98.58% (281) | hypothetical protein MMAR_1222 |
| M. avium 104 | MAV_4752 | - | 6e-25 | 33.47% (248) | hypothetical protein MAV_4752 |
| M. smegmatis MC2 155 | MSMEG_1733 | - | 6e-91 | 60.70% (285) | hypothetical protein MSMEG_1733 |
| M. thermoresistible (build 8) | TH_1835 | - | 1e-35 | 62.07% (116) | conserved hypothetical protein |
| M. vanbaalenii PYR-1 | Mvan_3817 | - | 4e-89 | 58.01% (281) | hypothetical protein Mvan_3817 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2272|M.bovis_AF2122/97 ------------------------MTRQQLDVQVKNGGLVRVWYGVYAAQ
Rv2248|M.tuberculosis_H37Rv ------------------------MTRQQLDVQVKNGGLVRVWYGVYAAQ
MAB_3617|M.abscessus_ATCC_1997 MHPSIRALFHG-RGAIRAGELQEILSAKRISSLIRDGHLHRPWHGVYTLP
MUL_2670|M.ulcerans_Agy99 --------------MATSAQVLTVLTRRGLEADLKNGVLSRVWHGIYGRG
MMAR_1222|M.marinum_M MHAELARLLDAQGGVATSAQVLTFLTRRGLEADLKSGVLSRVWHGIYGRG
MSMEG_1733|M.smegmatis_MC2_155 MNPQLMRLFDDQRGVATSGQILGLITRYAFDQALKTGVLERIWPGIYCLG
TH_1835|M.thermoresistible__bu --------------------------------------------------
Mflv_4824|M.gilvum_PYR-GCK MDDELLALFDAQRGVALSGQILSLVPRRRFEQWLNTVVLERIWQGVYCLG
Mvan_3817|M.vanbaalenii_PYR-1 -MTDLDAVFRAQGGVATSGQLLRFYSRSRLDIEIRDGWLIKVWPGVYSRD
MAV_4752|M.avium_104 --------MGEAPVVGSEELASGRLNRHRLRVAYRPVFPNVYLP---AQV
Mb2272|M.bovis_AF2122/97 EPDLLGRLAALDVFMGGHAVACLGTAAALYGFDTENTVAIHMLDPG-VRM
Rv2248|M.tuberculosis_H37Rv EPDLLGRLAALDVFMGGHAVACLGTAAALYGFDTENTVAIHMLDPG-VRM
MAB_3617|M.abscessus_ATCC_1997 NPTVEIQLRALDLVADAHVPVCMGTAAASYGFDTERDGALHVINPVPGQL
MUL_2670|M.ulcerans_Agy99 ELTSGLRLRGVDLAVGTPVAACLGTAAAAYGFDTEQTGDLHVLNPEGRQL
MMAR_1222|M.marinum_M ELTSGLRLRGVDLAVGTPVAACLGTAAAAYGFDTEQTGDLHVLNPEGRQL
MSMEG_1733|M.smegmatis_MC2_155 EPTEPLLLRGLDLSAGTRVAACLTTAAALHGFDTEGSTDLHVLNPPRHQL
TH_1835|M.thermoresistible__bu --------------------------------------------------
Mflv_4824|M.gilvum_PYR-GCK EADDALRLAGLDLSSGRRVAVCLGTAAAIFGFDTEQPRDLHVLNPPGCAL
Mvan_3817|M.vanbaalenii_PYR-1 EPDTMTRLRGLDLRAGEPVAICLGTAAAAYGFDTEDTHDIHALNPPRHQL
MAV_4752|M.avium_104 EPTLPLRIRAAWLWSGRTAVIAGAAAAAVHG--AAWIPDAVPIELIHHNT
Mb2272|M.bovis_AF2122/97 RPTVGLMVHQRVGAR--LQRVSG----RLATAPAWTAVEVARQLRRPRAL
Rv2248|M.tuberculosis_H37Rv RPTVGLMVHQRVGAR--LQRVSG----RLATAPAWTAVEVARQLRRPRAL
MAB_3617|M.abscessus_ATCC_1997 RPRPNLVVHQRLGAP--LRYVDG----RLTTAPDWTAIEIARTLRPSRAI
MUL_2670|M.ulcerans_Agy99 RSTDGLTVHRRAGAP--LTRLAG----RELRTPAWTAIEVARGLRRPRAL
MMAR_1222|M.marinum_M RSTDGLTVHRRAGAP--LTRLAG----RELTTPAWTAIEVARGLRRPRAL
MSMEG_1733|M.smegmatis_MC2_155 RSVDGLVVHRREGAP--LTVIDVDGDVRYVTAPAWTAVEVARALRRPRAL
TH_1835|M.thermoresistible__bu --------------------------------------------------
Mflv_4824|M.gilvum_PYR-GCK RDADGLVVHRRDGAP--LVTVEG----RRATSPAWTAIEVARSLRRPRAL
Mvan_3817|M.vanbaalenii_PYR-1 RNSDGLIVHRRDGAP--LGVADG----RPATTAAWTAVEVARSLRRPRAL
MAV_4752|M.avium_104 RAPDGVLIRRDGLCPGETQICDG----LAVTTPERTAFDIGRRGAVRSAV
Mb2272|M.bovis_AF2122/97 ATLEAALRSMRCARSEIENAVAEQRGRRGIVAARELLPFADGRAESAMES
Rv2248|M.tuberculosis_H37Rv ATLDAALRSMRCARSEIENAVAEQRGRRGIVAARELLPFADGRAESAMES
MAB_3617|M.abscessus_ATCC_1997 GTLDAALRSGHCSPGGLRHAARMQAGRRGIVHVRGLLTHADGRSESPMES
MUL_2670|M.ulcerans_Agy99 ATLDAALRSGTCDRDDLDRAVCLQSGRRGVVAVRELLALASPLAESPMES
MMAR_1222|M.marinum_M ATLDAALRSGTCDRDDLDRAVCLQSGRRGVVAVRELLALASPLAESPMES
MSMEG_1733|M.smegmatis_MC2_155 ATLDAALRSGKCTRADVWRAALDQAGRRGIVAVRNLIALADPRAESPMES
TH_1835|M.thermoresistible__bu -----------------------------------LIAIADGRAESPMES
Mflv_4824|M.gilvum_PYR-GCK ATLDAALRSGTCTRPDLWRAATEQKGRRGIVAVRNLLPLADARAESPGES
Mvan_3817|M.vanbaalenii_PYR-1 ATLDAALRSTSCTRQQLTVAAAEQAGRRGIVAVRELIPLADALAESPMES
MAV_4752|M.avium_104 VRLDSLARATGFKADDVLRVAGAHPRSPGLRRLEAALGLVDPGAQSPRES
: .. ::*. **
Mb2272|M.bovis_AF2122/97 EARLVMIDHGLPLPELQYPIHGHGGE-MWRVDFAWPDMRLAAEYESIEWH
Rv2248|M.tuberculosis_H37Rv EARLVMIDHGLPLPELQYPIHGHGGE-MWRVDFAWPDMRLAAEYESIEWH
MAB_3617|M.abscessus_ATCC_1997 ETRLLFIDSGVPAPELQATICDRYGT-VWRVDFLWRSARLIGEYDSDEWH
MUL_2670|M.ulcerans_Agy99 ETRLVMIEGGLPAPVLQYELVGSDGR-RWRLDFAWPGLRVAAEYDGVDWH
MMAR_1222|M.marinum_M ETRLVMIEGGLPAPVLQYELVGSDGR-RWRLDFAWPGLRVAAEYDGVDWH
MSMEG_1733|M.smegmatis_MC2_155 EARLMMLDAGLPAPELQHEVIDGMGK-LRRLDFAWPECRVAVEYDGDDWH
TH_1835|M.thermoresistible__bu EARLAMIDGGLPIPELQYELRDGAGR-LRRVDFAWPRHRVAVEYDGVDWH
Mflv_4824|M.gilvum_PYR-GCK AARLAMLDADLPVPHLQYEFVDGNGD-LRRLDFAWPEAGVAAEYDGVDWH
Mvan_3817|M.vanbaalenii_PYR-1 EARLAMLDGGLPPPVLQHEIVDLSGR-TWRVDFAWLDAKVAVEYDGFDWH
MAV_4752|M.avium_104 YLRLLLIDAGLPRPQTQVPVPGADGLPVAYLDMGWPEWMVAVEYDGDHHR
** ::: .:* * * . . * :*: * : **:. . :
Mb2272|M.bovis_AF2122/97 AGPAEMLRDKTRWAKLQELGWTIVPIVVDDVRREPGRLAARIARHLDRAR
Rv2248|M.tuberculosis_H37Rv AGPAEMLRDKTRWAKLQELGWTIVPIVVDDVRREPGRLAARIARHLDRAR
MAB_3617|M.abscessus_ATCC_1997 SGPAAMRKDKLKTARLQECGWTVIPITVDDIRRHRDELVARINTHLRHHA
MUL_2670|M.ulcerans_Agy99 SGPQAFLRDRRRSAALQELGWVIVPIVAGDVRHRPAELVQRLAGALARAQ
MMAR_1222|M.marinum_M SGPQAFLRDRRRSAALQELGWVIVPIVAGDVRHRPADLVQRLAGALARAQ
MSMEG_1733|M.smegmatis_MC2_155 GNPDALRNDRVRAAALSDVGWLVIAIVSEDVRLRPQETVGRIDRQLGLAR
TH_1835|M.thermoresistible__bu SGPDAMRRDRDRTAALMDVGWTVIAIVLEDVRYRTREFVGRVDAQLRRAQ
Mflv_4824|M.gilvum_PYR-GCK SGPDAMQRDRRRYSALLAVGMVVIPIVAEDLRDGGWEMASRIRDQLRRAR
Mvan_3817|M.vanbaalenii_PYR-1 SDQEHFARDRQKRAALNEVNWRMLSVVSDDVRKQSHDMVRRIEHELTRRI
MAV_4752|M.avium_104 TDRRQYVKDIRRLEMLEQLGWVIVRVVAEDR---PADIVRRVRAALAKSG
. .* : * . :: :. * . *: *
Mb2272|M.bovis_AF2122/97 MAG----
Rv2248|M.tuberculosis_H37Rv MAG----
MAB_3617|M.abscessus_ATCC_1997 A------
MUL_2670|M.ulcerans_Agy99 AA-----
MMAR_1222|M.marinum_M AA-----
MSMEG_1733|M.smegmatis_MC2_155 AA-----
TH_1835|M.thermoresistible__bu AA-----
Mflv_4824|M.gilvum_PYR-GCK AA-----
Mvan_3817|M.vanbaalenii_PYR-1 AA-----
MAV_4752|M.avium_104 VAPRLSV