For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
DDELLALFDAQRGVALSGQILSLVPRRRFEQWLNTVVLERIWQGVYCLGEADDALRLAGLDLSSGRRVAV CLGTAAAIFGFDTEQPRDLHVLNPPGCALRDADGLVVHRRDGAPLVTVEGRRATSPAWTAIEVARSLRRP RALATLDAALRSGTCTRPDLWRAATEQKGRRGIVAVRNLLPLADARAESPGESAARLAMLDADLPVPHLQ YEFVDGNGDLRRLDFAWPEAGVAAEYDGVDWHSGPDAMQRDRRRYSALLAVGMVVIPIVAEDLRDGGWEM ASRIRDQLRRARAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4824 | - | - | 100% (295) | hypothetical protein Mflv_4824 |
| M. gilvum PYR-GCK | Mflv_1335 | - | 4e-76 | 53.41% (279) | hypothetical protein Mflv_1335 |
| M. gilvum PYR-GCK | Mflv_1289 | - | 1e-25 | 33.21% (265) | hypothetical protein Mflv_1289 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2272 | - | 4e-72 | 53.31% (257) | hypothetical protein Mb2272 |
| M. tuberculosis H37Rv | Rv2248 | - | 1e-72 | 53.70% (257) | hypothetical protein Rv2248 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3617 | - | 1e-64 | 45.92% (294) | hypothetical protein MAB_3617 |
| M. marinum M | MMAR_1222 | - | 2e-93 | 60.68% (295) | hypothetical protein MMAR_1222 |
| M. avium 104 | MAV_0642 | - | 5e-22 | 33.48% (227) | hypothetical protein MAV_0642 |
| M. smegmatis MC2 155 | MSMEG_1733 | - | 1e-104 | 66.22% (299) | hypothetical protein MSMEG_1733 |
| M. thermoresistible (build 8) | TH_1835 | - | 4e-36 | 63.79% (116) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2670 | - | 2e-89 | 60.85% (281) | hypothetical protein MUL_2670 |
| M. vanbaalenii PYR-1 | Mvan_3817 | - | 1e-86 | 57.53% (292) | hypothetical protein Mvan_3817 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2272|M.bovis_AF2122/97 ------------------------MTRQQLDVQVKNGGLVRVWYGVYAAQ
Rv2248|M.tuberculosis_H37Rv ------------------------MTRQQLDVQVKNGGLVRVWYGVYAAQ
MAB_3617|M.abscessus_ATCC_1997 MHPSIRALFHG-RGAIRAGELQEILSAKRISSLIRDGHLHRPWHGVYTLP
MSMEG_1733|M.smegmatis_MC2_155 MNPQLMRLFDDQRGVATSGQILGLITRYAFDQALKTGVLERIWPGIYCLG
TH_1835|M.thermoresistible__bu --------------------------------------------------
Mflv_4824|M.gilvum_PYR-GCK MDDELLALFDAQRGVALSGQILSLVPRRRFEQWLNTVVLERIWQGVYCLG
MMAR_1222|M.marinum_M MHAELARLLDAQGGVATSAQVLTFLTRRGLEADLKSGVLSRVWHGIYGRG
MUL_2670|M.ulcerans_Agy99 --------------MATSAQVLTVLTRRGLEADLKNGVLSRVWHGIYGRG
Mvan_3817|M.vanbaalenii_PYR-1 -MTDLDAVFRAQGGVATSGQLLRFYSRSRLDIEIRDGWLIKVWPGVYSRD
MAV_0642|M.avium_104 --------------MAEPFIGSEAVASGLVTPYALRSRFVRVHPDVYVPA
Mb2272|M.bovis_AF2122/97 --EPDLLGRLAALDVFMGGHAVACLGTAAALYGFDTENTVAIHMLDPG-V
Rv2248|M.tuberculosis_H37Rv --EPDLLGRLAALDVFMGGHAVACLGTAAALYGFDTENTVAIHMLDPG-V
MAB_3617|M.abscessus_ATCC_1997 --NPTVEIQLRALDLVADAHVPVCMGTAAASYGFDTERDGALHVINPVPG
MSMEG_1733|M.smegmatis_MC2_155 --EPTEPLLLRGLDLSAGTRVAACLTTAAALHGFDTEGSTDLHVLNPPRH
TH_1835|M.thermoresistible__bu --------------------------------------------------
Mflv_4824|M.gilvum_PYR-GCK --EADDALRLAGLDLSSGRRVAVCLGTAAAIFGFDTEQPRDLHVLNPPGC
MMAR_1222|M.marinum_M --ELTSGLRLRGVDLAVGTPVAACLGTAAAAYGFDTEQTGDLHVLNPEGR
MUL_2670|M.ulcerans_Agy99 --ELTSGLRLRGVDLAVGTPVAACLGTAAAAYGFDTEQTGDLHVLNPEGR
Mvan_3817|M.vanbaalenii_PYR-1 --EPDTMTRLRGLDLRAGEPVAICLGTAAAAYGFDTEDTHDIHALNPPRH
MAV_0642|M.avium_104 GTALSAGLRARSAWLWSRRRGVVAGRSAAALYGTKWIDDRAPAQLLYPYR
Mb2272|M.bovis_AF2122/97 RMRPTVGLMVHQRVGARLQRVSG----RLATAPAWTAVEVARQLRRPRAL
Rv2248|M.tuberculosis_H37Rv RMRPTVGLMVHQRVGARLQRVSG----RLATAPAWTAVEVARQLRRPRAL
MAB_3617|M.abscessus_ATCC_1997 QLRPRPNLVVHQRLGAPLRYVDG----RLTTAPDWTAIEIARTLRPSRAI
MSMEG_1733|M.smegmatis_MC2_155 QLRSVDGLVVHRREGAPLTVIDVDGDVRYVTAPAWTAVEVARALRRPRAL
TH_1835|M.thermoresistible__bu --------------------------------------------------
Mflv_4824|M.gilvum_PYR-GCK ALRDADGLVVHRRDGAPLVTVEG----RRATSPAWTAIEVARSLRRPRAL
MMAR_1222|M.marinum_M QLRSTDGLTVHRRAGAPLTRLAG----RELTTPAWTAIEVARGLRRPRAL
MUL_2670|M.ulcerans_Agy99 QLRSTDGLTVHRRAGAPLTRLAG----RELRTPAWTAIEVARGLRRPRAL
Mvan_3817|M.vanbaalenii_PYR-1 QLRNSDGLIVHRRDGAPLGVADG----RPATTAAWTAVEVARSLRRPRAL
MAV_0642|M.avium_104 RPPDGIQTWSDRLVGDEIQTIGG----MPVTTPARTALDIACRSPVDKAV
Mb2272|M.bovis_AF2122/97 ATLEAALRSMRCARSEIENAVAEQRGRRGIVAARELLPFADGRAESAMES
Rv2248|M.tuberculosis_H37Rv ATLDAALRSMRCARSEIENAVAEQRGRRGIVAARELLPFADGRAESAMES
MAB_3617|M.abscessus_ATCC_1997 GTLDAALRSGHCSPGGLRHAARMQAGRRGIVHVRGLLTHADGRSESPMES
MSMEG_1733|M.smegmatis_MC2_155 ATLDAALRSGKCTRADVWRAALDQAGRRGIVAVRNLIALADPRAESPMES
TH_1835|M.thermoresistible__bu -----------------------------------LIAIADGRAESPMES
Mflv_4824|M.gilvum_PYR-GCK ATLDAALRSGTCTRPDLWRAATEQKGRRGIVAVRNLLPLADARAESPGES
MMAR_1222|M.marinum_M ATLDAALRSGTCDRDDLDRAVCLQSGRRGVVAVRELLALASPLAESPMES
MUL_2670|M.ulcerans_Agy99 ATLDAALRSGTCDRDDLDRAVCLQSGRRGVVAVRELLALASPLAESPMES
Mvan_3817|M.vanbaalenii_PYR-1 ATLDAALRSTSCTRQQLTVAAAEQAGRRGIVAVRELIPLADALAESPMES
MAV_0642|M.avium_104 AAIDALARATELKVLEIELLADRYRGRRGITRARNVLPLVDAGAESPRET
::. .. :**. *:
Mb2272|M.bovis_AF2122/97 EARLVMIDHGLPLPELQYPIHGHGGEMWRVDFAWPDMRLAAEYESIEWHA
Rv2248|M.tuberculosis_H37Rv EARLVMIDHGLPLPELQYPIHGHGGEMWRVDFAWPDMRLAAEYESIEWHA
MAB_3617|M.abscessus_ATCC_1997 ETRLLFIDSGVPAPELQATICDRYGTVWRVDFLWRSARLIGEYDSDEWHS
MSMEG_1733|M.smegmatis_MC2_155 EARLMMLDAGLPAPELQHEVIDGMGKLRRLDFAWPECRVAVEYDGDDWHG
TH_1835|M.thermoresistible__bu EARLAMIDGGLPIPELQYELRDGAGRLRRVDFAWPRHRVAVEYDGVDWHS
Mflv_4824|M.gilvum_PYR-GCK AARLAMLDADLPVPHLQYEFVDGNGDLRRLDFAWPEAGVAAEYDGVDWHS
MMAR_1222|M.marinum_M ETRLVMIEGGLPAPVLQYELVGSDGRRWRLDFAWPGLRVAAEYDGVDWHS
MUL_2670|M.ulcerans_Agy99 ETRLVMIEGGLPAPVLQYELVGSDGRRWRLDFAWPGLRVAAEYDGVDWHS
Mvan_3817|M.vanbaalenii_PYR-1 EARLAMLDGGLPPPVLQHEIVDLSGRTWRVDFAWLDAKVAVEYDGFDWHS
MAV_0642|M.avium_104 WLRLLLLRAGFPRPRTQLPVRQYGALIACLDMGWEDIKLAVEYDGDQHRT
** :: ..* * * . . :*: * : **:. : :
Mb2272|M.bovis_AF2122/97 GPAEMLRDKTRWAKLQELGWTIVPIVVDDVRREPGRLAARIARHLDRARM
Rv2248|M.tuberculosis_H37Rv GPAEMLRDKTRWAKLQELGWTIVPIVVDDVRREPGRLAARIARHLDRARM
MAB_3617|M.abscessus_ATCC_1997 GPAAMRKDKLKTARLQECGWTVIPITVDDIRRHRDELVARINTHLRHHAA
MSMEG_1733|M.smegmatis_MC2_155 NPDALRNDRVRAAALSDVGWLVIAIVSEDVRLRPQETVGRIDRQLGLARA
TH_1835|M.thermoresistible__bu GPDAMRRDRDRTAALMDVGWTVIAIVLEDVRYRTREFVGRVDAQLRRAQA
Mflv_4824|M.gilvum_PYR-GCK GPDAMQRDRRRYSALLAVGMVVIPIVAEDLRDGGWEMASRIRDQLRRARA
MMAR_1222|M.marinum_M GPQAFLRDRRRSAALQELGWVIVPIVAGDVRHRPADLVQRLAGALARAQA
MUL_2670|M.ulcerans_Agy99 GPQAFLRDRRRSAALQELGWVIVPIVAGDVRHRPAELVQRLAGALARAQA
Mvan_3817|M.vanbaalenii_PYR-1 DQEHFARDRQKRAALNEVNWRMLSVVSDDVRKQSHDMVRRIEHELTRRIA
MAV_0642|M.avium_104 DRRQFTKDIRRAEVLAELGWTVVRVTAEDT---PAGIIARVPTAWTRRAC
. : .* : * . :: :. * *:
Mb2272|M.bovis_AF2122/97 AG---------
Rv2248|M.tuberculosis_H37Rv AG---------
MAB_3617|M.abscessus_ATCC_1997 -----------
MSMEG_1733|M.smegmatis_MC2_155 A----------
TH_1835|M.thermoresistible__bu A----------
Mflv_4824|M.gilvum_PYR-GCK A----------
MMAR_1222|M.marinum_M A----------
MUL_2670|M.ulcerans_Agy99 A----------
Mvan_3817|M.vanbaalenii_PYR-1 A----------
MAV_0642|M.avium_104 TGSEKPARNSR