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VKHLPALTVPTRPSALRDSLDGSPQISRPLSCFCSHVPPVASAQPAAGPWDPLLPKLPSAGAPGDPVAIA NASLQATTLATQTAMNMGRNFLSSLGIVSPAADPSTSVRGNRVNGPQAIEYVIRRGGTQIGVPYSWGGGS LTGPTRGVDQGADTVGFDCSGLTRFAFAGVGMLLPRWSGDQYDAGRKVPPSQAKRGDLLFWGPGGSQHEA IYLGGGQMIEAQRTGVPIKVSPVRHAGMTPYVVRIIES
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3688 | - | - | 100% (248) | NLP/P60 protein |
| M. vanbaalenii PYR-1 | Mvan_3652 | - | e-113 | 92.38% (210) | NLP/P60 protein |
| M. vanbaalenii PYR-1 | Mvan_2748 | - | 1e-77 | 64.90% (208) | NLP/P60 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1514 | - | 1e-76 | 65.42% (214) | invasion protein |
| M. gilvum PYR-GCK | Mflv_2843 | - | 1e-115 | 94.29% (210) | NLP/P60 protein |
| M. tuberculosis H37Rv | Rv1478 | - | 1e-76 | 65.42% (214) | invasion protein |
| M. leprae Br4923 | MLBr_01811 | - | 5e-72 | 62.79% (215) | putative exported p60 protein homologue |
| M. abscessus ATCC 19977 | MAB_2728c | - | 5e-54 | 49.76% (209) | invasion protein Inv1 |
| M. marinum M | MMAR_2285 | iipB | 1e-74 | 63.68% (212) | invasion and intracellular persistence protein, IipB |
| M. avium 104 | MAV_3300 | - | 2e-71 | 60.27% (219) | invasin 1 |
| M. smegmatis MC2 155 | MSMEG_3146 | - | 1e-80 | 68.10% (210) | invasin 1 |
| M. thermoresistible (build 8) | TH_4058 | - | 1e-77 | 65.87% (208) | PUTATIVE NLP/P60 protein |
| M. ulcerans Agy99 | MUL_1487 | inv2 | 1e-74 | 63.68% (212) | invasion protein Inv2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3688|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2843|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2285|M.marinum_M --------------------------------------------------
MUL_1487|M.ulcerans_Agy99 --------------------------------------------------
Mb1514|M.bovis_AF2122/97 --------------------------------------------------
Rv1478|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01811|M.leprae_Br4923 --------------------------------------------------
MAV_3300|M.avium_104 --------------------------------------------------
MSMEG_3146|M.smegmatis_MC2_155 --------------------------------------------------
TH_4058|M.thermoresistible__bu --------------------------------------------------
MAB_2728c|M.abscessus_ATCC_199 MKRTVNDRFAVRGKRTVATALMVPPLLVAGLMMFPTTVAVTSAEPNDMAS
Mvan_3688|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2843|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2285|M.marinum_M --------------------------------------------------
MUL_1487|M.ulcerans_Agy99 --------------------------------------------------
Mb1514|M.bovis_AF2122/97 --------------------------------------------------
Rv1478|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01811|M.leprae_Br4923 --------------------------------------------------
MAV_3300|M.avium_104 --------------------------------------------------
MSMEG_3146|M.smegmatis_MC2_155 --------------------------------------------------
TH_4058|M.thermoresistible__bu --------------------------------------------------
MAB_2728c|M.abscessus_ATCC_199 LITQLADTNQQIEQLTADVQTQQESINKGLVDLQAARDNAASAAAQVAEG
Mvan_3688|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2843|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2285|M.marinum_M --------------------------------------------------
MUL_1487|M.ulcerans_Agy99 --------------------------------------------------
Mb1514|M.bovis_AF2122/97 --------------------------------------------------
Rv1478|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01811|M.leprae_Br4923 --------------------------------------------------
MAV_3300|M.avium_104 --------------------------------------------------
MSMEG_3146|M.smegmatis_MC2_155 --------------------------------------------------
TH_4058|M.thermoresistible__bu --------------------------------------------------
MAB_2728c|M.abscessus_ATCC_199 QRAVDAANGAIEEAQGKFDRMAAATYMAGPSTSYLTATNPDDVVRLASVT
Mvan_3688|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2843|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2285|M.marinum_M --------------------------------------------------
MUL_1487|M.ulcerans_Agy99 --------------------------------------------------
Mb1514|M.bovis_AF2122/97 --------------------------------------------------
Rv1478|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01811|M.leprae_Br4923 --------------------------------------------------
MAV_3300|M.avium_104 --------------------------------------------------
MSMEG_3146|M.smegmatis_MC2_155 --------------------------------------------------
TH_4058|M.thermoresistible__bu --------------------------------------------------
MAB_2728c|M.abscessus_ATCC_199 KSVEASSQTVMDNLRRARTEQVNKQSQARAIQEKADQAAADAQQQQDDLV
Mvan_3688|M.vanbaalenii_PYR-1 -------MKHLPALTVPTR---PSALRDS-LDGSPQISRPLSCFCSHVPP
Mflv_2843|M.gilvum_PYR-GCK ---MGLHVRSKGAAIASTDRCDPAILVAGRVRRLPGVIAIVVLLFLACAP
MMAR_2285|M.marinum_M ----------------MSSYRGPMRYKRFRLLGLAWITLAVAALLVVVSA
MUL_1487|M.ulcerans_Agy99 -----------------------MRYKRFRLLGLAWITLAVAALMVVVSA
Mb1514|M.bovis_AF2122/97 -----------------------MRHTRFHPIKLAWITAVVAGLMVGVAT
Rv1478|M.tuberculosis_H37Rv -----------------------MRHTRFHPIKLAWITAVVAGLMVGVAT
MLBr_01811|M.leprae_Br4923 -----------------------MRHKNFRLINLAGLTAMVAGLIIVVTI
MAV_3300|M.avium_104 -----------------------MRRNRFRLIVFAWITAMVTGLMFSVAP
MSMEG_3146|M.smegmatis_MC2_155 -----------------------------MVLRALIAVVAVAFAAVGLVA
TH_4058|M.thermoresistible__bu -------------------VVILLRSKTFRLLRPLIPAILGLGVLIAAAG
MAB_2728c|M.abscessus_ATCC_199 SAMKDVQKKLEAQRGVAADLTAKKKSAEAQLAAARGPAYAASTATARVIN
Mvan_3688|M.vanbaalenii_PYR-1 VASAQPAAG--------------PWDPLLPKLPSAGAPGDPVAIANASLQ
Mflv_2843|M.gilvum_PYR-GCK VASAQPAAG--------------PWDPLLPKIPSAGAPGDPVAIANASLQ
MMAR_2285|M.marinum_M P--ADADPG--------------GWDPTLPATASAGAPGDALAMANASLQ
MUL_1487|M.ulcerans_Agy99 P--ADADPG--------------GWDPTLPATASAGAPGDALAMANASLQ
Mb1514|M.bovis_AF2122/97 P--ADAEPG--------------QWDPTLPALVSAGAPGDPLAVANASLQ
Rv1478|M.tuberculosis_H37Rv P--ADAEPG--------------QWDPTLPALVSAGAPGDPLAVANASLQ
MLBr_01811|M.leprae_Br4923 P--ATADPG--------------QWDPTLPAAVSAGAPGDPLAVANASLQ
MAV_3300|M.avium_104 TPAALADPG--------------EWDPTLPAQISAGAPGDPLAVANASLQ
MSMEG_3146|M.smegmatis_MC2_155 PAGAAPEDG--------------QWDPTLPKLISAGAPGDPLAIANASLE
TH_4058|M.thermoresistible__bu PATAAPDDG--------------QWDPTLPKLISAGAPGDPLAIANASLA
MAB_2728c|M.abscessus_ATCC_199 PSAAIAGNGNEWTEGPAPVSSGGQWDTTLPMIASANVPTDPTQTINMVLG
* . * **. ** **..* *. * *
Mvan_3688|M.vanbaalenii_PYR-1 ATTLATQTAMNMGRNFLSSLGIVSPA---ADPSTSVRG------NRVNGP
Mflv_2843|M.gilvum_PYR-GCK ATAMATQTAMNMGRSFLSSLGIVSPA---ADPSTSVRG------NRVNGA
MMAR_2285|M.marinum_M ATAQATQTTLDLGRQFLGGLGINLGG--SPAPSAANTG--ANRIPRVYGQ
MUL_1487|M.ulcerans_Agy99 ATAQATQTTLDLGRQFLGGLGINLGG--SPAPSAANTG--ANRIPRVYGR
Mb1514|M.bovis_AF2122/97 ATAQATQTTLDLGRQFLGGLGINLGGPAASAPSAATTG--ASRIPRANAR
Rv1478|M.tuberculosis_H37Rv ATAQATQTTLDLGRQFLGGLGINLGGPAASAPSAATTG--ASRIPRANAR
MLBr_01811|M.leprae_Br4923 VTAQATQTTLDLGKQFLGRLGINFGG-DPSNAATTSSNP-GGRIPRVYGG
MAV_3300|M.avium_104 ATAQATQTTLNLGKQFLGGLGINLGGNDAPAAAATPSNP-GGKIPRVYGR
MSMEG_3146|M.smegmatis_MC2_155 ATAQATQVTMGLGRKFLASLGLVEDT---PAAAGVAPG-------RVRGP
TH_4058|M.thermoresistible__bu ATAQATQVTMDLGRKFLASIGLGGSQ---PVSS-VAPG-------RVRGP
MAB_2728c|M.abscessus_ATCC_199 IGNTAANVGQSA---VCGVIGIFCPK---AAPAAAASGEGGEYLPKVYGR
*::. . . . :*: . .: . :. .
Mvan_3688|M.vanbaalenii_PYR-1 QAIEYVIRRGGTQIGVPYSWGGGSLTGPTRGVDQGADTVGFDCSGLTRFA
Mflv_2843|M.gilvum_PYR-GCK QAIEYVIRRAGTQIGVPYSWGGGSLTGPSRGVDQGAGTVGFDCSGLTRFA
MMAR_2285|M.marinum_M QALEYVIRRGGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLMRYA
MUL_1487|M.ulcerans_Agy99 QALEYVIRRGGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLMRYA
Mb1514|M.bovis_AF2122/97 QAVEYVIRRAGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYA
Rv1478|M.tuberculosis_H37Rv QAVEYVIRRAGSQMGVPYSWGGGSLQGPSKGVDSGANTVGFDCSGLVRYA
MLBr_01811|M.leprae_Br4923 QAIEYVIKRGGAQIGVPYSWGGGSLQGPSKGVGDGANITGFDCSGLMRYA
MAV_3300|M.avium_104 QAIEYVIKRMGSQMGVPYSWGGGSLDGPSKGVGDGANITGFDCSGLMRYG
MSMEG_3146|M.smegmatis_MC2_155 QAIEYVIRRGGTQMGVPYSWGGGKPNGPSRGIDSGANTVGFDCSGFTQFS
TH_4058|M.thermoresistible__bu QAIEYVIRRGASQLGVPYSWGGGKPSGPSTGVGSGANTVGFDCSGFTQFA
MAB_2728c|M.abscessus_ATCC_199 ENVERVIARAGSAMGTPYSWGGGSYNGPTRGIDSGAGTVGYDCSGLMMYG
: :* ** * .: :*.*******. **: *:..**. .*:****: :.
Mvan_3688|M.vanbaalenii_PYR-1 FAGVGMLLPRWSGDQYDAGRKVPPSQAKRGDLLFWGPGGSQHEAIYLGGG
Mflv_2843|M.gilvum_PYR-GCK FAGVGVLLPRWSGDQYDAGRKVPPSQAKRGDLLFWGPGGSQHEAIYLGGG
MMAR_2285|M.marinum_M FAGVGVLIPRYSGDQYNAGRHISPDQARRGDLIFYGPGGSQHVTMYLGNG
MUL_1487|M.ulcerans_Agy99 FAGVGVLIPRYSGDQYNAGRHISPDQARRGDLIFYGPGGSQHVTMYLGNG
Mb1514|M.bovis_AF2122/97 FAGVGVLIPRFSGDQYNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNG
Rv1478|M.tuberculosis_H37Rv FAGVGVLIPRFSGDQYNAGRHVPPAEAKRGDLIFYGPGGGQHVTLYLGNG
MLBr_01811|M.leprae_Br4923 FAGVGVLIPRFSGDQYNAGRHLTPDQAKRGDLIFYGPGGGQHVTMYLGNG
MAV_3300|M.avium_104 FAGVGVLIPRFSGDQYNAGRHIPQDQARRGDLIFYGPGGSQHVTMYLGNG
MSMEG_3146|M.smegmatis_MC2_155 FAGVGVLIPKYSGDQYNTGRKVPVNQAKRGDLLFWGPGGSQHVALYLGGG
TH_4058|M.thermoresistible__bu FAGVGVLIPKYSGDQYNTGRKVPVSQAKRGDLLFWGPGGSQHVALYLGNG
MAB_2728c|M.abscessus_ATCC_199 FAAVGIRLRHYTGYQYNSGRKVPSAQMKRGDMIFYGPNASQHVALYLGNG
**.**: : :::* **::**::. : :***::*:**...** ::***.*
Mvan_3688|M.vanbaalenii_PYR-1 QMIEAQRTGVPIKVSPVRHAGMTPYVVRIIES
Mflv_2843|M.gilvum_PYR-GCK QMIEAQQTGVPIKVSPVRTGGMTPYVVRIIES
MMAR_2285|M.marinum_M QMLEASGSAGKVTVSPVRKAGMTPFVTRIIEY
MUL_1487|M.ulcerans_Agy99 QMLEASGSAGKVTVSPVRKAGMTPFVTRIIEY
Mb1514|M.bovis_AF2122/97 QMLEASGSAGKVTVSPVRKAGMTPFVTRIIEY
Rv1478|M.tuberculosis_H37Rv QMLEASGSAGKVTVSPVRKAGMTPFVTRIIEY
MLBr_01811|M.leprae_Br4923 QMLEASSSVGKVTVSSVRKAGMTPFVTRIIES
MAV_3300|M.avium_104 QMLEASGSAGKVTVSPVRKPGMTPFLTRIIEY
MSMEG_3146|M.smegmatis_MC2_155 KMLEASGSAGKVTVSPVRMSGLQPYAARIIES
TH_4058|M.thermoresistible__bu QMLEASGSAGKVVAGPVRTAGLQPYAARIIET
MAB_2728c|M.abscessus_ATCC_199 QMLEAPNTGDVVKVSPVRTSGMTPYVTRMIEW
:*:** : : ...** *: *: .*:**