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M. vanbaalenii PYR-1 Mvan_3684 (-)

annotation: helix-turn-helix domain-containing protein
coordinates: 3915979 - 3916842
length: 287

ERHALEARSSGVASGDHDDTDARTPRTMSHPHPDRSADDAQPRWGGAALLRPGVLAFAGSIGATDAHAHH
AVQIITAATPLTVTDEQGASHTGTKVVVPTDAAHRIRAGAQDGTVVFLEPESAPGRAAHLRAIDSGWAIS
SALAFTAHRPLATVVAELVAHLSPATFEHDVPARHSSVDHALRLLPALLAAGPVRGTELAARVGLSASRF
THLFTAQVGIPLRRYVLWSRLRIAITLVQGGDDLTGAAHGAGFADSAHLTRTTREMFGLPPSVLSRHVSW
DLDPSS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_3684--100% (287)helix-turn-helix domain-containing protein
M. vanbaalenii PYR-1Mvan_3649-e-10173.97% (242) helix-turn-helix domain-containing protein
M. vanbaalenii PYR-1Mvan_1839-1e-1633.19% (229) helix-turn-helix domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3863-4e-0527.56% (127) AraC family transcriptional regulator
M. gilvum PYR-GCKMflv_2796-1e-3034.73% (239) helix-turn-helix domain-containing protein
M. tuberculosis H37RvRv3833-4e-0527.56% (127) AraC family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0066c-1e-3238.33% (240) AraC family transcriptional regulator
M. marinum M-----
M. avium 104MAV_0221-4e-0627.05% (244) transcriptional regulator, AraC family protein
M. smegmatis MC2 155MSMEG_2039-6e-1544.34% (106) putative transcriptional regulator
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb3863|M.bovis_AF2122/97            -----------------------------------MSENSHHRLATTSLT
Rv3833|M.tuberculosis_H37Rv         -----------------------------------MSENSHHRLATTSLT
Mflv_2796|M.gilvum_PYR-GCK          ----------------------------------MRTRHTRDVTWLGEAL
MAB_0066c|M.abscessus_ATCC_199      ------------------------------------------MVWTGAAV
Mvan_3684|M.vanbaalenii_PYR-1       MERHALEARSSGVASGDHDDTDARTPRTMSHPHPDRSADDAQPRWGGAAL
MSMEG_2039|M.smegmatis_MC2_155      --------------------------------MPTPIPTPLPRTCYPAVW
MAV_0221|M.avium_104                -------------------------MYRPSPPLAEHIEYFGYWRGDEALG
                                                                                      

Mb3863|M.bovis_AF2122/97            LPPG--------ARIERHRHPSHQIVYPSAGAVSVTTHAGTWITPVNRAI
Rv3833|M.tuberculosis_H37Rv         LPPG--------ARIERHRHPSHQIVYPSAGAVSVTTHAGTWITPVNRAI
Mflv_2796|M.gilvum_PYR-GCK          IEPGKLVFRGQLGSAHAHGHAALQIVTIDEGAAFLVDADGRGLWAP--AA
MAB_0066c|M.abscessus_ATCC_199      IEPGRLVYRGALGDTHRHTHAAVQIAIALDGTLQLTDGADRRVSTR--AA
Mvan_3684|M.vanbaalenii_PYR-1       LRPGVLAFAGSIGATDAHAHHAVQIITAAT-PLTVTDEQGASHTGT--KV
MSMEG_2039|M.smegmatis_MC2_155      LWPGQGLYSGPALGLQPHSGSVWCLVVGVDAPLTVDVG-GHQISAR--TA
MAV_0221|M.avium_104                VHTSRALPRGAVTAIIDVGGRTDLGFYASDARTPLTVPPAFAAGAGATAY
                                    : ..                              :               

Mb3863|M.bovis_AF2122/97            WIPAGCWHQHKFHGHTQFHGVALDPQRYRGGPATPTVLAVNPLMRELIIA
Rv3833|M.tuberculosis_H37Rv         WIPAGCWHQHKFHGHTQFHGVALDPQRYRGGPATPTVLAVNPLMRELVIA
Mflv_2796|M.gilvum_PYR-GCK          IIPAGAEHSIEAEACQGMM-LYLEPTSVIGSAVTALFRNTNRNDVREWVR
MAB_0066c|M.abscessus_ATCC_199      VIPAGAQHTVHGGTSTGLM-IYLEPTCFEGRALGALFDNAARDDATAWCA
Mvan_3684|M.vanbaalenii_PYR-1       VVPTDAAHRIRAGAQDGTV-VFLEPESAPGRAAHLRAIDSGWAISSALAF
MSMEG_2039|M.smegmatis_MC2_155      LIPPRVTHHLAMIG--PLVSCYLDPASHRTASCRRQFDDIVHGIGIGHHR
MAV_0221|M.avium_104                VVRVAPAHTVMTIHFRPAGALAFLGSPLSDLEDALVGLEDLWGRDAALLR
                                     :     *              :                           

Mb3863|M.bovis_AF2122/97            CSQADRTDTDEHHRMLAVLQDQLPTTSIREPLWVPSPTDRRLRHACALIA
Rv3833|M.tuberculosis_H37Rv         CSQADRTDTDEHHRMLAVLQDQLPTTSIREPLWVPSPTDRRLRHACALIA
Mflv_2796|M.gilvum_PYR-GCK          LGKKLVNINVVEQQHLSSAASEVIAYLVGSEGQPRCAVHPGVEAAVDLLP
MAB_0066c|M.abscessus_ATCC_199      AASELSDI-----QDDSSSAESVIARLVG--DVHASEPHESVREAIRLLP
Mvan_3684|M.vanbaalenii_PYR-1       TAHRPLAT---------VVAELVAHLSPATFEHDVPARHSSVDHALRLLP
MSMEG_2039|M.smegmatis_MC2_155      EDLLLNPP---------ADDSSAVRWLDTAAPSVIHDIDPRIELAAKQIR
MAV_0221|M.avium_104                EQLIDAGS---------PPRRVALLQAFLVRRMRRNAVWPPARLAPVLRG
                                                                                *     

Mb3863|M.bovis_AF2122/97            DNLTQ-PLTLQQIGGRIGVSQRTLSRLFSDELGMTFPQWRTQLRLQHALV
Rv3833|M.tuberculosis_H37Rv         DNLTQ-PLTLQQIGGRIGVSQRTLSRLFSDELGMTFPQWRTQLRLQHALV
Mflv_2796|M.gilvum_PYR-GCK          GIIEG-PVKLSDVARTVHLSADRLGRLFAHEVGMSIPAYVRWCRLIRAME
MAB_0066c|M.abscessus_ATCC_199      GMLTG-PVRLAEVARVVHLSADRLGRMFARDTGMSFPAYVRWARLIRTIE
Mvan_3684|M.vanbaalenii_PYR-1       ALLAAGPVRGTELAARVGLSASRFTHLFTAQVGIPLRRYVLWSRLRIAIT
MSMEG_2039|M.smegmatis_MC2_155      DDPAT-VVAAAELAATAGLSESRFLHLFRAELGTSLRRYRMWCRLLRAGA
MAV_0221|M.avium_104                ADLDP-SMRVSKAQELSGLSRKRFAALFRCEVGLSPKAYLRVLRLQAALR
                                           :   .      :*   :  :*  : * .   :    **  :  

Mb3863|M.bovis_AF2122/97            LLAERHDVTSVASECGWATPSAFIDTYRQAFGHTPGQAAKPMAATRLTRL
Rv3833|M.tuberculosis_H37Rv         LLAERHDVTSVASECGWATPSAFIDTYRQAFGHTPGQAAKPMAATRLTRL
Mflv_2796|M.gilvum_PYR-GCK          VVRDGGTITDAAHAAGFSDSAHANRVFHEMFGLAPIDARRGVRLT-----
MAB_0066c|M.abscessus_ATCC_199      VARTGGTLTDAAHAAGFSDSSHANRAFHEMFGITPVELHRSVQLS-----
Mvan_3684|M.vanbaalenii_PYR-1       LVQGGDDLTGAAHGAGFADSAHLTRTTREMFGLPPSVLSRHVSWDLDPSS
MSMEG_2039|M.smegmatis_MC2_155      LLATGHDLTTAAVDSGFASPSHLADRFKSTFGLSASQLLATGLQIRVP--
MAV_0221|M.avium_104                ALDTPARGATIAADLGYFDQAHFVREFRAFTGATPTQYARRRSSMPGHVE
                                            :  *   *:   :      :   * ..               

Mb3863|M.bovis_AF2122/97            RRARDRR
Rv3833|M.tuberculosis_H37Rv         RRARDRR
Mflv_2796|M.gilvum_PYR-GCK          -------
MAB_0066c|M.abscessus_ATCC_199      -------
Mvan_3684|M.vanbaalenii_PYR-1       -------
MSMEG_2039|M.smegmatis_MC2_155      -------
MAV_0221|M.avium_104                LAR----