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TAATAAPLPQTCYPAVWLWPGHVVYAGPALNLEPHSGSVWCLVVGADEPLTVTAGGHQVVARSVLVPPRL VHHLDTHGGRLVSCYLDPSSGRASACRDQCELAAAGLMTGHPHEAALTALPTDDDSAGRWLDLAAPAPRA RTDPRVAEAIRRIAADPAGAPPSRRLAAEIGLSESRFLHLFRQESGTSLRRYRLWMRLMQAGAAVSSGTN LTDAAADAGFASPSHLADRFKSTFGLTATDLISSGTVLRMMGDRPRSPGE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1839 | - | - | 100% (261) | helix-turn-helix domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3684 | - | 9e-17 | 33.19% (229) | helix-turn-helix domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_3649 | - | 1e-15 | 31.17% (231) | helix-turn-helix domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3863 | - | 2e-07 | 27.97% (118) | AraC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2796 | - | 1e-11 | 26.29% (232) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | Rv3833 | - | 2e-07 | 27.97% (118) | AraC family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0066c | - | 6e-14 | 27.43% (226) | AraC family transcriptional regulator |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4981 | - | 2e-07 | 32.69% (104) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_2039 | - | 2e-82 | 58.96% (251) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_3718 | - | 9e-05 | 32.18% (87) | PUTATIVE putative aldehyde dehydrogenase |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1839|M.vanbaalenii_PYR-1 ---------------------MTAATAAPLPQTCYP--AVWLWPGHVVYA
MSMEG_2039|M.smegmatis_MC2_155 ---------------------MPTPIPTPLPRTCYP--AVWLWPGQGLYS
Mb3863|M.bovis_AF2122/97 ---------------------MSENSHHRLATTS-------------LTL
Rv3833|M.tuberculosis_H37Rv ---------------------MSENSHHRLATTS-------------LTL
Mflv_2796|M.gilvum_PYR-GCK ---------------------MRTRHTRDVTWLG----EALIEPGKLVFR
MAB_0066c|M.abscessus_ATCC_199 -----------------------------MVWTG----AAVIEPGRLVYR
TH_3718|M.thermoresistible__bu ---------------VAAADLIDTAVEAGIPADRCLR-GTWLTRSDLAAA
MAV_4981|M.avium_104 MADSSATPRVVVIVVFDDVTMLDVAGAGEVFAEANRFGADYLLKIASVDG
:
Mvan_1839|M.vanbaalenii_PYR-1 GPALNLEPHSGSVWCLVVGADEPLTVTAGG---HQVVAR-----------
MSMEG_2039|M.smegmatis_MC2_155 GPALGLQPHSGSVWCLVVGVDAPLTVDVGG---HQISAR-----------
Mb3863|M.bovis_AF2122/97 PPGARIERHRHPSHQIVYPSAGAVSVTTHAGTWITPVNR-----------
Rv3833|M.tuberculosis_H37Rv PPGARIERHRHPSHQIVYPSAGAVSVTTHAGTWITPVNR-----------
Mflv_2796|M.gilvum_PYR-GCK GQLGSAHAHGHAALQIVTIDEGAAFLVDADG--RGLWAP-----------
MAB_0066c|M.abscessus_ATCC_199 GALGDTHRHTHAAVQIAIALDGTLQLTDGAD--RRVSTR-----------
TH_3718|M.thermoresistible__bu DRLITAEQELRIVRNVLAATEHPTALAGSAGARYQLPRAGFLGFALLSSN
MAV_4981|M.avium_104 RDVTTSIGTRLGVTDAVSSIESADTVLVAGS--DNLPRRPIDPELVEAVK
. :
Mvan_1839|M.vanbaalenii_PYR-1 ----------SVLVPPRLVHHLDTHGG-RLVSCYLD----PSSGR---AS
MSMEG_2039|M.smegmatis_MC2_155 ----------TALIPPRVTHHLAMIG--PLVSCYLD----PASHR---TA
Mb3863|M.bovis_AF2122/97 ----------AIWIPAGCWHQHKFHGHTQFHGVALD----PQRYRGGPAT
Rv3833|M.tuberculosis_H37Rv ----------AIWIPAGCWHQHKFHGHTQFHGVALD----PQRYRGGPAT
Mflv_2796|M.gilvum_PYR-GCK ----------AAIIPAGAEHSIEAEAC-QGMMLYLE----PTSVIGSAVT
MAB_0066c|M.abscessus_ATCC_199 ----------AAVIPAGAQHTVHGGTS-TGLMIYLE----PTCFEGRALG
TH_3718|M.thermoresistible__bu TLGDAIRVGIRFWRLTSVFERVTLEVNRQTTAIVLDDRDVPADVRQFLVE
MAV_4981|M.avium_104 SVADRTRRLASICTGSFILGQAGLLDGRRATTHWHDVRLFARAFPEITVE
. : .
Mvan_1839|M.vanbaalenii_PYR-1 ACRDQCEL----AAAGLMTGHPHEAALTALPTDDDSAGRWLDLAAPAPRA
MSMEG_2039|M.smegmatis_MC2_155 SCRRQFDD----IVHGIGIGHHREDLLLNPPADDSSAVRWLDTAAPSVIH
Mb3863|M.bovis_AF2122/97 PTVLAVNP----LMRELIIACSQADRTDTDEHHRMLAVLQDQLPTTSIRE
Rv3833|M.tuberculosis_H37Rv PTVLAVNP----LMRELVIACSQADRTDTDEHHRMLAVLQDQLPTTSIRE
Mflv_2796|M.gilvum_PYR-GCK ALFRNTNR----NDVREWVRLGKKLVNINVVEQQHLSSAASEVIAYLVGS
MAB_0066c|M.abscessus_ATCC_199 ALFDNAAR----DDATAWCAAASELSDI-----QDDSSSAESVIARLVG-
TH_3718|M.thermoresistible__bu RDAATMVG----VTPALLGGPLPDGVRMSLRRRPNGDAAVEELVDVSYGA
MAV_4981|M.avium_104 PDALFVCDGDVFTSAGISSGIDLALALVEMDYGTELVRAVARWLVVYLKR
Mvan_1839|M.vanbaalenii_PYR-1 --------------------------------------RTDPRVAEAIR-
MSMEG_2039|M.smegmatis_MC2_155 --------------------------------------DIDPRIELAAK-
Mb3863|M.bovis_AF2122/97 P--------------------------------LWVPSPTDRRLRHACA-
Rv3833|M.tuberculosis_H37Rv P--------------------------------LWVPSPTDRRLRHACA-
Mflv_2796|M.gilvum_PYR-GCK E--------------------------------GQPRCAVHPGVEAAVD-
MAB_0066c|M.abscessus_ATCC_199 ---------------------------------DVHASEPHESVREAIR-
TH_3718|M.thermoresistible__bu DRNAITFPTALLDRPLAAANPAVAAQCIAQCDELLARHQDEPTVASRVRR
MAV_4981|M.avium_104 AGGQ------------------------SQFSALVEAEPPPRSPLRKVTA
Mvan_1839|M.vanbaalenii_PYR-1 RIAADPAGAPPSRRLAAEIGLSESRFLHLFRQESGTSLRRYRLWMRLMQA
MSMEG_2039|M.smegmatis_MC2_155 QIRDDPATVVAAAELAATAGLSESRFLHLFRAELGTSLRRYRMWCRLLRA
Mb3863|M.bovis_AF2122/97 LIADNLTQPLTLQQIGGRIGVSQRTLSRLFSDELGMTFPQWRTQLRLQHA
Rv3833|M.tuberculosis_H37Rv LIADNLTQPLTLQQIGGRIGVSQRTLSRLFSDELGMTFPQWRTQLRLQHA
Mflv_2796|M.gilvum_PYR-GCK LLPGIIEGPVKLSDVARTVHLSADRLGRLFAHEVGMSIPAYVRWCRLIRA
MAB_0066c|M.abscessus_ATCC_199 LLPGMLTGPVRLAEVARVVHLSADRLGRMFARDTGMSFPAYVRWARLIRT
TH_3718|M.thermoresistible__bu RLARDPGAVPLMRTLATEMGFTERTLRRRLAR-EGTGYRSLIDEVRGARA
MAV_4981|M.avium_104 AISADPAADHSVKSLSARASLSTRQLTRLFQSELGTTPARYVEMVRIDAA
: :. .: : : : * * :
Mvan_1839|M.vanbaalenii_PYR-1 GAAVSSGTNLTDAAADAGFASPSHLADRFKSTFGLTATDLISSGTVLRMM
MSMEG_2039|M.smegmatis_MC2_155 GALLATGHDLTTAAVDSGFASPSHLADRFKSTFGLSASQLLATGLQIRVP
Mb3863|M.bovis_AF2122/97 LVLLAERHDVTSVASECGWATPSAFIDTYRQAFGHTPGQAAKPMAATRLT
Rv3833|M.tuberculosis_H37Rv LVLLAERHDVTSVASECGWATPSAFIDTYRQAFGHTPGQAAKPMAATRLT
Mflv_2796|M.gilvum_PYR-GCK MEVVRDGGTITDAAHAAGFSDSAHANRVFHEMFGLAPIDARRGVRLT---
MAB_0066c|M.abscessus_ATCC_199 IEVARTGGTLTDAAHAAGFSDSSHANRAFHEMFGITPVELHRSVQLS---
TH_3718|M.thermoresistible__bu ADLLSGGATVKQVAQQLGYSEPAAFHHAFVRWHALPPARFRRADVR----
MAV_4981|M.avium_104 RAALDAGRSVAESARLAGFGSAETLRRVFVEHLGLSPKAYRDRFRTAARG
: * *:. . : . ..
Mvan_1839|M.vanbaalenii_PYR-1 GDRPRSPGE
MSMEG_2039|M.smegmatis_MC2_155 ---------
Mb3863|M.bovis_AF2122/97 RLRRARDRR
Rv3833|M.tuberculosis_H37Rv RLRRARDRR
Mflv_2796|M.gilvum_PYR-GCK ---------
MAB_0066c|M.abscessus_ATCC_199 ---------
TH_3718|M.thermoresistible__bu ---------
MAV_4981|M.avium_104 ---------