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PTPIPTPLPRTCYPAVWLWPGQGLYSGPALGLQPHSGSVWCLVVGVDAPLTVDVGGHQISARTALIPPRV THHLAMIGPLVSCYLDPASHRTASCRRQFDDIVHGIGIGHHREDLLLNPPADDSSAVRWLDTAAPSVIHD IDPRIELAAKQIRDDPATVVAAAELAATAGLSESRFLHLFRAELGTSLRRYRMWCRLLRAGALLATGHDL TTAAVDSGFASPSHLADRFKSTFGLSASQLLATGLQIRVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2039 | - | - | 100% (251) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5465 | - | 2e-08 | 28.07% (171) | transcriptional regulator, AraC family protein |
| M. smegmatis MC2 155 | MSMEG_6356 | - | 5e-07 | 24.43% (221) | AraC family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3863 | - | 2e-09 | 29.23% (130) | AraC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2796 | - | 1e-10 | 26.84% (231) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | Rv3833 | - | 2e-09 | 29.23% (130) | AraC family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0066c | - | 2e-12 | 26.32% (228) | AraC family transcriptional regulator |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_0193 | - | 3e-09 | 27.82% (133) | transcriptional regulator, AraC family protein |
| M. thermoresistible (build 8) | TH_3937 | - | 5e-05 | 24.50% (249) | PUTATIVE putative transcriptional regulator, AraC family |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1839 | - | 2e-82 | 58.96% (251) | helix-turn-helix domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2039|M.smegmatis_MC2_155 -----MPTPIPTPLPRTCYPAVWLWPGQG---------LYSGPALGLQPH
Mvan_1839|M.vanbaalenii_PYR-1 -----MTAATAAPLPQTCYPAVWLWPGHV---------VYAGPALNLEPH
Mflv_2796|M.gilvum_PYR-GCK -------MRTRHTRDVTWLGEALIEPGKL---------VFRGQLGSAHAH
MAB_0066c|M.abscessus_ATCC_199 ---------------MVWTGAAVIEPGRL---------VYRGALGDTHRH
Mb3863|M.bovis_AF2122/97 --------MSENSHHRLATTSLTLPPG-----------------ARIERH
Rv3833|M.tuberculosis_H37Rv --------MSENSHHRLATTSLTLPPG-----------------ARIERH
MAV_0193|M.avium_104 --------MSEIGQHGLATSAQTLPPG-----------------ARIARH
TH_3937|M.thermoresistible__bu VSDDTMVATAERQGPITRSRTELTDPSEVGDFLEAVYGVRVSRVRPPRSH
*. *
MSMEG_2039|M.smegmatis_MC2_155 SGSVWCLVVGVDA-------------------------------------
Mvan_1839|M.vanbaalenii_PYR-1 SGSVWCLVVGADE-------------------------------------
Mflv_2796|M.gilvum_PYR-GCK GHAALQIVTIDEG-------------------------------------
MAB_0066c|M.abscessus_ATCC_199 THAAVQIAIALDG-------------------------------------
Mb3863|M.bovis_AF2122/97 RHPSHQIVYPSAG-------------------------------------
Rv3833|M.tuberculosis_H37Rv RHPSHQIVYPSAG-------------------------------------
MAV_0193|M.avium_104 RHPLHQIVYPSTG-------------------------------------
TH_3937|M.thermoresistible__bu DGPLLTHVRADAGSFIVDRLHIAGELHTTADPIHKVVTLWPTSGRVVGRC
. .
MSMEG_2039|M.smegmatis_MC2_155 -PLTVDVG-GHQIS----------------ARTALIPPRVTHHLAMIG--
Mvan_1839|M.vanbaalenii_PYR-1 -PLTVTAG-GHQVV----------------ARSVLVPPRLVHHLDTHGG-
Mflv_2796|M.gilvum_PYR-GCK -AAFLVDADGRGLW----------------APAAIIPAGAEHSIEAEAC-
MAB_0066c|M.abscessus_ATCC_199 -TLQLTDGADRRVS----------------TRAAVIPAGAQHTVHGGTS-
Mb3863|M.bovis_AF2122/97 -AVSVTTHAGTWITP--------------VNRAIWIPAGCWHQHKFHGHT
Rv3833|M.tuberculosis_H37Rv -AVSVTTHAGTWITP--------------VNRAIWIPAGCWHQHKFHGHT
MAV_0193|M.avium_104 -AVSVTTPAGTWITP--------------ANRAIWIPAGCWHEHKFHGHT
TH_3937|M.thermoresistible__bu AGLEGRAGAGEIILSGQPDLVRQTHCDDLAATVILLDPALVAHVASGSAG
. : : .
MSMEG_2039|M.smegmatis_MC2_155 PLVSCYLDPASHRTASCRRQFDDIVHGIGIGHHREDLLLNPP--------
Mvan_1839|M.vanbaalenii_PYR-1 RLVSCYLDPSSGRASACRDQCELAAAGLMTGHPHEAALTALP--------
Mflv_2796|M.gilvum_PYR-GCK QGMMLYLEPTSVIGSAVTALFRNTNRNDVREWVRLGKKLVNINVVEQQHL
MAB_0066c|M.abscessus_ATCC_199 TGLMIYLEPTCFEGRALGALFDNAARDDATAWCAAASELSDI-----QDD
Mb3863|M.bovis_AF2122/97 QFHGVALDPQRYRGGPATPTVLAVNPLMRELIIACSQADRTDTDEHHRML
Rv3833|M.tuberculosis_H37Rv QFHGVALDPQRYRGGPATPTVLAVNPLMRELVIACSQADRTDTDEHHRML
MAV_0193|M.avium_104 NFHGVALDPARYRRGPAAPAVLAVTPLMRELIIACSRARDTDAGAHHRML
TH_3937|M.thermoresistible__bu DDAAAAIRFASLRPAVGATRLWQDTVRYVRDHVLVDDTRATPLVVGQAAR
:
MSMEG_2039|M.smegmatis_MC2_155 -ADDSSAVRWLDTAAPSVIHDIDPR----IELAAKQIRDDPATVVAAAEL
Mvan_1839|M.vanbaalenii_PYR-1 -TDDDSAGRWLDLAAPAPRARTDPR----VAEAIRRIAADPAGAPPSRRL
Mflv_2796|M.gilvum_PYR-GCK SSAASEVIAYLVGSEGQPRCAVHPG----VEAAVDLLPGIIEGPVKLSDV
MAB_0066c|M.abscessus_ATCC_199 SSSAESVIARLVG--DVHASEPHES----VREAIRLLPGMLTGPVRLAEV
Mb3863|M.bovis_AF2122/97 AVLQDQLPTTSIREPLWVPSPTDRR----LRHACALIADNLTQPLTLQQI
Rv3833|M.tuberculosis_H37Rv AVLQDQLPTTSIREPLWVPSPTDRR----LRHACALIADNLTQPLTLQQI
MAV_0193|M.avium_104 AVLHDQLQATSVAEPLWIPTAVDGR----LRAACALIADNLREPLTLRQI
TH_3937|M.thermoresistible__bu LLAAVTASAFPNSAAEPAGQTVNGQRPPLLRRALDYIDANAAADISLADI
. : * : :
MSMEG_2039|M.smegmatis_MC2_155 AATAGLSESRFLHLFRAELGTSLRRYRMWCRLLRAGALLATGH----DLT
Mvan_1839|M.vanbaalenii_PYR-1 AAEIGLSESRFLHLFRQESGTSLRRYRLWMRLMQAGAAVSSGT----NLT
Mflv_2796|M.gilvum_PYR-GCK ARTVHLSADRLGRLFAHEVGMSIPAYVRWCRLIRAMEVVRDGG----TIT
MAB_0066c|M.abscessus_ATCC_199 ARVVHLSADRLGRMFARDTGMSFPAYVRWARLIRTIEVARTGG----TLT
Mb3863|M.bovis_AF2122/97 GGRIGVSQRTLSRLFSDELGMTFPQWRTQLRLQHALVLLAERH----DVT
Rv3833|M.tuberculosis_H37Rv GGRIGVSQRTLSRLFSDELGMTFPQWRTQLRLQHALVLLAERH----DVT
MAV_0193|M.avium_104 GERIGVGQRTLSRLFRDELAMTFPQWRTQVRLQHALVLLAERR----DVT
TH_3937|M.thermoresistible__bu AAAVHVTPRALQYMFRRHLQTTPLQYLRRIRLHRAHHDLLAQTPASDTVG
. : : :* . : : ** :: :
MSMEG_2039|M.smegmatis_MC2_155 TAAVDSGFASPSHLADRFKSTFGLSASQLLATGLQIRVP---------
Mvan_1839|M.vanbaalenii_PYR-1 DAAADAGFASPSHLADRFKSTFGLTATDLISSGTVLRMMGDRPRSPGE
Mflv_2796|M.gilvum_PYR-GCK DAAHAAGFSDSAHANRVFHEMFGLAPIDARRG---VRLT---------
MAB_0066c|M.abscessus_ATCC_199 DAAHAAGFSDSSHANRAFHEMFGITPVELHRS---VQLS---------
Mb3863|M.bovis_AF2122/97 SVASECGWATPSAFIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
Rv3833|M.tuberculosis_H37Rv SVASECGWATPSAFIDTYRQAFGHTPGQAAKPMAATRLTRLRRARDRR
MAV_0193|M.avium_104 SVAAECGWATPSAFIDTYRRAFGHTPGRLAP-----RPS---------
TH_3937|M.thermoresistible__bu AIAARWGFAHAGRFAMQYRQTYGRSPHQTLRG----------------
* *:: .. :: :* :.