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TRPADPTAPLAQANSGRVGRRADRRWALIRLASPFILLAVWQLGSAVGLIPQDVLPAPSLIAEAGIELIG NGQLVDALTVSGLRVVEGLILGGVIGIALGTAVGLSKWFEATVDPPMQMVRALPHLGLIPLFIIWFGIGE LPKVLLVALGVSFPLYLNTFSAIRQVDPKLFETAQVLGFSFWQRFRSIIVPSAAPQVLVGLRQSLAIAWL TLIVAEQINADKGIGFLIMNARDFLRIDIIIFGLIVYALLGIGTDAVVRALERRALRYRS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3413 | - | - | 100% (271) | binding-protein-dependent transport systems inner membrane component |
| M. vanbaalenii PYR-1 | Mvan_0121 | - | 1e-33 | 30.97% (268) | binding-protein-dependent transport systems inner membrane |
| M. vanbaalenii PYR-1 | Mvan_3142 | - | 1e-17 | 27.08% (240) | binding-protein-dependent transport systems inner membrane |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3782c | proZ | 7e-11 | 28.31% (166) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. gilvum PYR-GCK | Mflv_3159 | - | 1e-53 | 41.22% (279) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv3756c | proZ | 7e-11 | 28.31% (166) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2216 | - | 1e-108 | 76.61% (248) | sulfonate ABC transporter, permease protein SsuC |
| M. marinum M | MMAR_0033 | - | 9e-13 | 24.71% (259) | hypothetical protein MMAR_0033 |
| M. avium 104 | MAV_2433 | - | 1e-113 | 80.48% (251) | putative aliphatic sulfonates transport permease protein SsuC |
| M. smegmatis MC2 155 | MSMEG_3854 | - | 1e-124 | 84.64% (267) | putative aliphatic sulfonates transport permease protein SsuC |
| M. thermoresistible (build 8) | TH_4654 | - | 1e-48 | 40.25% (236) | PUTATIVE putative binding-protein-dependent transport systems |
| M. ulcerans Agy99 | MUL_4374 | proZ | 8e-12 | 26.06% (165) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3413|M.vanbaalenii_PYR-1 ----MTRPADPTAPLAQANSGRVG--RRADRRW-----------ALIRLA
MSMEG_3854|M.smegmatis_MC2_155 ------MLAAPTAPTVTR--------RLSHRKW-----------AIIRVI
MAV_2433|M.avium_104 MSIATALDAAPKRLGGAASGAPGG--LWARRKW-----------EVVRLV
MAB_2216|M.abscessus_ATCC_1997 MTTRNTLVAAAATDSDAPESGPSRREWVLERRW-----------EIVRFL
Mflv_3159|M.gilvum_PYR-GCK MTAVAAPLTTP--RGPAAPAPELVDVIAGHRGR-RSIWG-RIPRPVRRMA
TH_4654|M.thermoresistible__bu VTSLQTARPAPRLRSPAQRRADVTDAQLLHRGEHRTRLGPGRAVPAALAV
Mb3782c|M.bovis_AF2122/97 --------------------------------------------------
Rv3756c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4374|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0033|M.marinum_M ---MSVAGNDINVEGAVKGGAEGPPTAPTTPGR-----------------
Mvan_3413|M.vanbaalenii_PYR-1 SPFILLAVWQLGSAVGLIPQDVLPAPSLIAEAGIELIGNGQLVDALTVSG
MSMEG_3854|M.smegmatis_MC2_155 SPVVLLGLWQLGSAVGLISQDVLPAPSLIVEAGIELIRNGQLADALRVSG
MAV_2433|M.avium_104 SPLALLALWQLGSAIGVIAQDVLPAPSLILQAGVELTRNGQLADALHIST
MAB_2216|M.abscessus_ATCC_1997 SPLAVLLIWQAGSAWGLIDPDILPAPSTIARAGFELIANGQLAEALRVSG
Mflv_3159|M.gilvum_PYR-GCK GPVAILAVWTIGSTSGLLNTDLFPPPSDVAVTAWHLLTNGGLALHVGTSA
TH_4654|M.thermoresistible__bu GPLLLVALWLITSQLGILDPRTLPHPFDIARTAAELWSDGRLPANVAASL
Mb3782c|M.bovis_AF2122/97 -------------------MNFLQQALSYLLTASNWTGPVGLAVRTCEHL
Rv3756c|M.tuberculosis_H37Rv -------------------MNFLQQALSYLLTASNWTGPVGLAVRTCEHL
MUL_4374|M.ulcerans_Agy99 -------------------MNFLQQALSYLSTAANWTGSAGLAHRTAEHL
MMAR_0033|M.marinum_M PSVGRWALQPLTCAFAVAGALAYVTVADVSESERRSLSVSHLLQLLREHL
: . *
Mvan_3413|M.vanbaalenii_PYR-1 LRVVEGLILGGVIGIALGTAVG--LSKWFEATVDPPMQMVRALPHLGLIP
MSMEG_3854|M.smegmatis_MC2_155 ARVVIGLLLGGVIGVALGTAVG--LSRWLEATVDPPMQMIRALPHLGLIP
MAV_2433|M.avium_104 VRVIEGLALGGVIGIVAGAAVG--LSRWVEATVDPPLQMIRALPHLGLIP
MAB_2216|M.abscessus_ATCC_1997 VRAAEGLLLGGVIGVVLGAAVG--LSRLADAVVDPTMQMIRALPHLGLIP
Mflv_3159|M.gilvum_PYR-GCK TRVLIGTALGITVGVVLAVLAG--LTRTGEDLLDWSMQILKAVPNFALTP
TH_4654|M.thermoresistible__bu KLSLISLAIGVAAGLALALLAG--LSRIGEALVDGPIQIKRAVPTLAIIP
Mb3782c|M.bovis_AF2122/97 EYTAVAVAASALIAVPVGLLIG--HTGRGTLLVVGAVNGLRALPTLGVLL
Rv3756c|M.tuberculosis_H37Rv EYTAVAVAASALIAVPVGLLIG--HTGRGTLLVVGAVNGLRALPTLGVLL
MUL_4374|M.ulcerans_Agy99 EYTALAATASALVAIPIGLIIG--HTGRGQLLVVSAVNGLRALPTLGVLL
MMAR_0033|M.marinum_M VISLSATVLTCVVAIPVGIALTRGSMRRYSKPIITVAGFGQAAPAIGLIA
. .: . : :* * :.:
Mvan_3413|M.vanbaalenii_PYR-1 LFIIWFGIGELPKVLLVALGVSFPLYLNTFSAIRQVDPKLFETAQVLGFS
MSMEG_3854|M.smegmatis_MC2_155 LFIVWFGIGELPKVLLVALGVSFPLYLNTFSAIRQVDPKLFETAQVLGFS
MAV_2433|M.avium_104 LFILWFGIGELPKVLLVALGVVFPLYLNTFSAIRQVDPKMLETAQVLGFS
MAB_2216|M.abscessus_ATCC_1997 LFIVWFGIGELPKVLMVALGAAFPLYLNTTSAIRQVDPKLFETAQVLGFS
Mflv_3159|M.gilvum_PYR-GCK LLIIWMGIGEGPKIVLITMGVAIAVYINTYSGIRGVDQQLVEMAQTLEAR
TH_4654|M.thermoresistible__bu LAIIWFGIGDTMKIVIIATSVLIPVYINTTAQLKGVDLRHVELAQTVGLS
Mb3782c|M.bovis_AF2122/97 LGVLLFGLGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMT
Rv3756c|M.tuberculosis_H37Rv LGVLLFGLGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMT
MUL_4374|M.ulcerans_Agy99 LGVLLFGLGLGPPIVALMLLGMPPLLAGTYAGIASVDPLVVDAARAMGMT
MMAR_0033|M.marinum_M LGAVVFGIGQLGAIVALTVYGAMPIIANTVTGLDGVDRRIVEAARGMGLS
* : :*:* :: : .: .* : : ** .: *: :
Mvan_3413|M.vanbaalenii_PYR-1 FWQRFRSIIVPSAAPQVLVGLRQSLAIAWLTLIVAEQINADKGIGFLIMN
MSMEG_3854|M.smegmatis_MC2_155 FWQRFRTIIVPSAAPQVLVGFRQSLAIAWLTLIVAEQINADSGIGFLINN
MAV_2433|M.avium_104 FFQRFRRILVPGTAPQVLVGLRQSLAIAWLTLIVAEQINADKGIGFLINN
MAB_2216|M.abscessus_ATCC_1997 FWQRLRVIVIPGATPQVLVGLRQSLALSWLTLIVAEQINADAGVGFLINN
Mflv_3159|M.gilvum_PYR-GCK RGTLITQVILPGAMPNFLVGLRLGLSSAWLSLIFAEMINTTEGIGFLMSR
TH_4654|M.thermoresistible__bu RVQFIRKVALPGALPGFFTGLRLAVTISWTALVVVEQVNATSGVGFLMTQ
Mb3782c|M.bovis_AF2122/97 ESQVLLRVEVPNALPLMLGGLR-SATLQVVATATVAAYASLGGLGGYLID
Rv3756c|M.tuberculosis_H37Rv ESQVLLRVEVPNALPLMLGGLR-SATLQVVATATVAAYASLGGLGGYLID
MUL_4374|M.ulcerans_Agy99 EAQVVLRVEMPNALPLILGGLR-SATLQVVATVTVAAYASLGGLGRYLID
MMAR_0033|M.marinum_M AFSTLRRVELPLSLPVIVAGVR-TALVLIVGTAALASFTGGGGLGQLITT
. : :* : * .. *.* *:* :
Mvan_3413|M.vanbaalenii_PYR-1 ARDFLRIDIIIFGLIVYALLGIGTDAVVRALERRALRYRS----------
MSMEG_3854|M.smegmatis_MC2_155 ARDFLRIDIIIFGLIVYALLGIGTDAIVRALERRALRYRT----------
MAV_2433|M.avium_104 ARDFLRIDIIIFGLTIYALLGIITDAVVRLIERRAVRYRH----------
MAB_2216|M.abscessus_ATCC_1997 ARDFLRIDVIIFGLVVYALLGIVTDAIVRVLERRALRYRS----------
Mflv_3159|M.gilvum_PYR-GCK AQTNLQFDVSLLVIVIYAVLGLASYALVRLLERLLLSWRNGFAGFEATA-
TH_4654|M.thermoresistible__bu ARLYGQLEVVVVGLVVYAVFGLAGDHLVRTIERRALSWRRALGG------
Mb3782c|M.bovis_AF2122/97 GIKERRFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKL-----
Rv3756c|M.tuberculosis_H37Rv GIKERRFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKL-----
MUL_4374|M.ulcerans_Agy99 GIKERQSHIALVGALMVAALALSLDGLLALAGWASVPGTGRVSRFWHQPD
MMAR_0033|M.marinum_M GIKLQQPVTLIVGAILVAALALFIDWLARLIEMVAAPRGL----------
. : :. : * :.: :
Mvan_3413|M.vanbaalenii_PYR-1 --------------------
MSMEG_3854|M.smegmatis_MC2_155 --------------------
MAV_2433|M.avium_104 --------------------
MAB_2216|M.abscessus_ATCC_1997 --------------------
Mflv_3159|M.gilvum_PYR-GCK --------------------
TH_4654|M.thermoresistible__bu --------------------
Mb3782c|M.bovis_AF2122/97 ----AAVVDKPAAGGGHALR
Rv3756c|M.tuberculosis_H37Rv ----AAVVDKPAAGGGHALR
MUL_4374|M.ulcerans_Agy99 DRIDVAVSANSAAVGSHVLR
MMAR_0033|M.marinum_M --------------------