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VSVFVDIAADPDLGARHHARGADARPGRSRWRGRVTRAALPLLSLLVFGVVWQFAAASGVWNQTFVPYPA TVWGAFVDVSTTHDGVRGYAGYLLWEHLYMTLRRVLAGVAIGVVLGVLLGLVMGSVSWVRSVLEPWLTFL RALPPLAYFFLLVIWLGIDEAPKITLLALAALPPAAVATTAAVVAAPVGLQEAARALGASRRQVIRDVVV PSALPETFTGIRLAVGMAYSSVVAAELFNGIPGVGGLVKDASNYNNTPVVLVGIFAIGFSGLVIDGLLRA AERRAVPWRGKV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0121 | - | - | 100% (292) | binding-protein-dependent transport systems inner membrane component |
| M. vanbaalenii PYR-1 | Mvan_3413 | - | 2e-33 | 30.97% (268) | binding-protein-dependent transport systems inner membrane |
| M. vanbaalenii PYR-1 | Mvan_3142 | - | 5e-16 | 23.55% (259) | binding-protein-dependent transport systems inner membrane |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3782c | proZ | 6e-18 | 30.88% (204) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. gilvum PYR-GCK | Mflv_0724 | - | 1e-137 | 89.67% (271) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv3756c | proZ | 7e-18 | 30.88% (204) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2176 | - | 1e-131 | 81.16% (292) | ABC transporter permease |
| M. marinum M | MMAR_5299 | proZ | 6e-17 | 29.44% (197) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. avium 104 | MAV_2433 | - | 3e-35 | 30.80% (289) | putative aliphatic sulfonates transport permease protein SsuC |
| M. smegmatis MC2 155 | MSMEG_0113 | - | 1e-132 | 82.65% (294) | taurine transport system permease protein TauC |
| M. thermoresistible (build 8) | TH_4654 | - | 4e-31 | 33.46% (257) | PUTATIVE putative binding-protein-dependent transport systems |
| M. ulcerans Agy99 | MUL_4374 | proZ | 7e-18 | 30.96% (197) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0121|M.vanbaalenii_PYR-1 MSVFVDIAADPDLGARHHARGADARPGRSRWRGR--------VTRAALPL
Mflv_0724|M.gilvum_PYR-GCK -----------------MPR-AGARPAR-QWRSR--------LARAALPL
MSMEG_0113|M.smegmatis_MC2_155 MSVFVDIVPG---SETDSPR--PAAPSN-RGRAI--------LTKALLPL
MAB_2176|M.abscessus_ATCC_1997 MSVFVDIVPE-------ESRGTRAVPRPSQWRVR--------LTRAALPL
MAV_2433|M.avium_104 --MSIATALDAAPKR--LGGAASGAPGGLWAR----------RKWEVVRL
TH_4654|M.thermoresistible__bu -VTSLQTARPAPRLRSPAQRRADVTDAQLLHRGEHRTRLGPGRAVPAALA
Mb3782c|M.bovis_AF2122/97 --------------------------------------------------
Rv3756c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5299|M.marinum_M --------------------------------------------------
MUL_4374|M.ulcerans_Agy99 --------------------------------------------------
Mvan_0121|M.vanbaalenii_PYR-1 LSLLVFGVVWQFAAASGVWNQTFVPYPATVWGAFVDVSTTHDGVRGYAGY
Mflv_0724|M.gilvum_PYR-GCK LSVVVFGVVWQLAAASGIWNQTFVPYPATVWNAFVDVSTTHDGVRGYAGY
MSMEG_0113|M.smegmatis_MC2_155 LSVAVFFAVWQAVAVAGIWNQTFVPYPSAVWRAFIDLSTTHDGVRGYAGY
MAB_2176|M.abscessus_ATCC_1997 LSVVVFIGVWQLAAASGIWNQTFVPYPSSVWHAFVEVSTDHDGVHGYGGY
MAV_2433|M.avium_104 VSPLALLALWQLGSAIGVIAQDVLPAPSLILQAGVELTRNGQ--------
TH_4654|M.thermoresistible__bu VGPLLLVALWLITSQLGILDPRTLPHPFDIARTAAELWSDGR--------
Mb3782c|M.bovis_AF2122/97 --------------------MNFLQQALSYLLTASNWTGPVG--------
Rv3756c|M.tuberculosis_H37Rv --------------------MNFLQQALSYLLTASNWTGPVG--------
MMAR_5299|M.marinum_M --------------------MNFLQQALSYLSTAANWTGSAG--------
MUL_4374|M.ulcerans_Agy99 --------------------MNFLQQALSYLSTAANWTGSAG--------
: . : :
Mvan_0121|M.vanbaalenii_PYR-1 LLWEHLYMTLRRVLAGVAIGVVLGVLLGLVMGSVSWVRSVLEPWLTFLRA
Mflv_0724|M.gilvum_PYR-GCK LLWEHLYMTLRRVFAGVLIGVALGVLLGLLMGSVPWLRSVLEPWLTFLRA
MSMEG_0113|M.smegmatis_MC2_155 LLVEHLYMTLRRVVAGVVIGVVLGVLLGLLMGSVGWLRSVLEPWLTFLRA
MAB_2176|M.abscessus_ATCC_1997 LLIEHLYMTLRRLLFGVLIGITAGVLLGLLMGSVGWVRSVLEPWLTFLRT
MAV_2433|M.avium_104 -LADALHISTVRVIEGLALGGVIGIVAGAAVGLSRWVEATVDPPLQMIRA
TH_4654|M.thermoresistible__bu -LPANVAASLKLSLISLAIGVAAGLALALLAGLSRIGEALVDGPIQIKRA
Mb3782c|M.bovis_AF2122/97 -LAVRTCEHLEYTAVAVAASALIAVPVGLLIGHTGRGTLLVVGAVNGLRA
Rv3756c|M.tuberculosis_H37Rv -LAVRTCEHLEYTAVAVAASALIAVPVGLLIGHTGRGTLLVVGAVNGLRA
MMAR_5299|M.marinum_M -LAHRTAEHLEYTALAVTASALVAIPIGLIIGHTGRGQLLVVSAVNGLRA
MUL_4374|M.ulcerans_Agy99 -LAHRTAEHLEYTALAATASALVAIPIGLIIGHTGRGQLLVVSAVNGLRA
* . . .: . * : : *:
Mvan_0121|M.vanbaalenii_PYR-1 LPPLAYFFLLVIWLGIDEAPKITLLALAALPPAAVATTAAVVAAPVGLQE
Mflv_0724|M.gilvum_PYR-GCK LPPLAYFFLLVIWLGIDEAPKITLLALAALPAAAVPTTAAVVAAPVGLTE
MSMEG_0113|M.smegmatis_MC2_155 LPPLAYFFLLVIWLGIDEAPKITLLALAALPPAAVATTAAVVAAPVGLQE
MAB_2176|M.abscessus_ATCC_1997 LPPLAYFFLLVIWLGIDEAPKITLLALAALPPAAVATTAAVVAAPVGLVE
MAV_2433|M.avium_104 LPHLGLIPLFILWFGIGELPKVLLVALGVVFPLYLNTFSAIRQVDPKMLE
TH_4654|M.thermoresistible__bu VPTLAIIPLAIIWFGIGDTMKIVIIATSVLIPVYINTTAQLKGVDLRHVE
Mb3782c|M.bovis_AF2122/97 LPTLGVLLLGVLLFGLGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVD
Rv3756c|M.tuberculosis_H37Rv LPTLGVLLLGVLLFGLGLGPPLVALMLLGIPSLLASTYAGIASVDPLVVD
MMAR_5299|M.marinum_M LPTLGVLLLGVLLFGLGLGPPIVALMLLGMPPLLAGTYAGIASVDPLVVD
MUL_4374|M.ulcerans_Agy99 LPTLGVLLLGVLLFGLGLGPPIVALMLLGMPPLLAGTYAGIASVDPLVVD
:* *. : * :: :*:. : : : . * : : . :
Mvan_0121|M.vanbaalenii_PYR-1 AARALGASRRQVIRDVVVPSALPETFTGIRLAVGMAYSSVVAAELFNGIP
Mflv_0724|M.gilvum_PYR-GCK AARALGASRGQVIRDVVIPSALPETFTGIRLAVGMAYSAVVAAELFNGIP
MSMEG_0113|M.smegmatis_MC2_155 AARALGATRAQVIRDVVVPSALPETFTGIRLAVGMAYSSVVAAELFNGIP
MAB_2176|M.abscessus_ATCC_1997 AARALGASRWQVTRDVVIPAALPETFTGVRLAVGMAYSSVVAAELFNGIP
MAV_2433|M.avium_104 TAQVLGFSFFQRFRRILVPGTAPQVLVGLRQSLAIAWLTLIVAEQINADK
TH_4654|M.thermoresistible__bu LAQTVGLSRVQFIRKVALPGALPGFFTGLRLAVTISWTALVVVEQVNATS
Mb3782c|M.bovis_AF2122/97 AARAMGMTESQVLLRVEVPNALPLMLGGLRSAT-LQVVATATVAAYASLG
Rv3756c|M.tuberculosis_H37Rv AARAMGMTESQVLLRVEVPNALPLMLGGLRSAT-LQVVATATVAAYASLG
MMAR_5299|M.marinum_M AARAMGMTEAQVVLRVEMPNALPLILGGLRSAT-LQVVATATVAAYASLG
MUL_4374|M.ulcerans_Agy99 AARAMGMTEAQVVLRVEMPNALPLILGGLRSAT-LQVVATVTVAAYASLG
*:.:* : * : :* : * : *:* : : : .. .
Mvan_0121|M.vanbaalenii_PYR-1 GVGGLVKDASNYNNTPVVLVGIFAIGFSGLVIDGLLRAAERRAVPWRGKV
Mflv_0724|M.gilvum_PYR-GCK GVGGLVKDASNYNNTPVVLVGIFAIGISGLVIDGLLRAAERRSVPWRGMI
MSMEG_0113|M.smegmatis_MC2_155 GVGGLVKDASNYNNTPVVLVGIFAIGFSGLVIDGLLRAVERRAVPWIGKV
MAB_2176|M.abscessus_ATCC_1997 GVGGLVKDASNYNNTPVVLVGIFSIGISGLVIDAALRAVERRAVPWRGKI
MAV_2433|M.avium_104 GIGFLINNARDFLRIDIIIFGLTIYALLGIITDAVVRLIERRAVRYRH--
TH_4654|M.thermoresistible__bu GVGFLMTQARLYGQLEVVVVGLVVYAVFGLAGDHLVRTIERRALSWRRAL
Mb3782c|M.bovis_AF2122/97 GLGGYLIDGIKERRFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRM
Rv3756c|M.tuberculosis_H37Rv GLGGYLIDGIKERRFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRM
MMAR_5299|M.marinum_M GLGRYLIDGIKERQFHIALVGALMVAALALSLDGLLALAGWASVPGTGRL
MUL_4374|M.ulcerans_Agy99 GLGRYLIDGIKERQSHIALVGALMVAALALSLDGLLALAGWASVPGTGRV
*:* : :. . : :.* . .: * : ::
Mvan_0121|M.vanbaalenii_PYR-1 ----------------------------
Mflv_0724|M.gilvum_PYR-GCK ----------------------------
MSMEG_0113|M.smegmatis_MC2_155 ----------------------------
MAB_2176|M.abscessus_ATCC_1997 ----------------------------
MAV_2433|M.avium_104 ----------------------------
TH_4654|M.thermoresistible__bu GG--------------------------
Mb3782c|M.bovis_AF2122/97 RKL---------AAVVDKPAAGGGHALR
Rv3756c|M.tuberculosis_H37Rv RKL---------AAVVDKPAAGGGHALR
MMAR_5299|M.marinum_M SRFWHQSDDRIDVAVSPNSAAVGSHVLR
MUL_4374|M.ulcerans_Agy99 SRFWHQPDDRIDVAVSANSAAVGSHVLR