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SVAGNDINVEGAVKGGAEGPPTAPTTPGRPSVGRWALQPLTCAFAVAGALAYVTVADVSESERRSLSVSH LLQLLREHLVISLSATVLTCVVAIPVGIALTRGSMRRYSKPIITVAGFGQAAPAIGLIALGAVVFGIGQL GAIVALTVYGAMPIIANTVTGLDGVDRRIVEAARGMGLSAFSTLRRVELPLSLPVIVAGVRTALVLIVGT AALASFTGGGGLGQLITTGIKLQQPVTLIVGAILVAALALFIDWLARLIEMVAAPRGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0033 | - | - | 100% (269) | hypothetical protein MMAR_0033 |
| M. marinum M | MMAR_5299 | proZ | 5e-31 | 37.57% (189) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. marinum M | MMAR_0035 | - | 3e-28 | 33.33% (204) | ABC transporter permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3782c | proZ | 3e-29 | 35.98% (189) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. gilvum PYR-GCK | Mflv_3110 | - | 6e-44 | 36.86% (255) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv3756c | proZ | 3e-29 | 35.98% (189) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. leprae Br4923 | MLBr_02093 | pstA1 | 2e-05 | 23.40% (141) | membrane-bound component of phosphate transport |
| M. abscessus ATCC 19977 | MAB_1227 | - | 5e-99 | 75.40% (248) | ABC transporter permease |
| M. avium 104 | MAV_0320 | - | 1e-27 | 34.39% (189) | ABC transporter, permease protein |
| M. smegmatis MC2 155 | MSMEG_2925 | - | 1e-104 | 76.17% (256) | permease membrane component |
| M. thermoresistible (build 8) | TH_3904 | - | 1e-101 | 74.80% (250) | PUTATIVE conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_0032 | - | 4e-57 | 99.14% (116) | hypothetical protein MUL_0032 |
| M. vanbaalenii PYR-1 | Mvan_5598 | - | 1e-31 | 37.85% (177) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3782c|M.bovis_AF2122/97 ------------------------------------------------MN
Rv3756c|M.tuberculosis_H37Rv ------------------------------------------------MN
MAV_0320|M.avium_104 ------------------------------------------------MN
Mvan_5598|M.vanbaalenii_PYR-1 ------------------------------------------------MN
MAB_1227|M.abscessus_ATCC_1997 -----MTASTITATGAAQS---APATARRPALAAR-----QLLQPSACIV
MSMEG_2925|M.smegmatis_MC2_155 -----MTTTAPDTERVALP---AEPSSR--LGLGR-----WLIQPLVCVA
TH_3904|M.thermoresistible__bu -----VTATVDDTGDTGHTGCTGTAGDRASRSAARRWA-RRTVQPVLCLV
MMAR_0033|M.marinum_M -----MSVAGNDINVEGAVKGGAEGPPTAPTTPGRPSVGRWALQPLTCAF
MUL_0032|M.ulcerans_Agy99 -----MGAAATHVCLRGGR-------SAGLCDGGR---------CVRVGA
Mflv_3110|M.gilvum_PYR-GCK -----MTATAEVSAEPSTDRESPGTGDPSGTTTAERLR--LLIQPVLVLV
MLBr_02093|M.leprae_Br4923 MNLDTLDRPVKAVVLRPISVRRRIKNNVATMFFFTSFLIALVPLVWLLSV
Mb3782c|M.bovis_AF2122/97 FLQQALSYLLTASNWT------GPVGLAVRTCEHLEYTAVAVAASALIAV
Rv3756c|M.tuberculosis_H37Rv FLQQALSYLLTASNWT------GPVGLAVRTCEHLEYTAVAVAASALIAV
MAV_0320|M.avium_104 FVQRAIAYLLSADNWT------GPVGLAARILEHLEYTGIAVGASALIAV
Mvan_5598|M.vanbaalenii_PYR-1 FLQEALSFIFTAANWG------GPAGLSARILEHLQYTVIAVFFSAVIAV
MAB_1227|M.abscessus_ATCC_1997 AVMVSLAYVNLADVSASEKRSLGMSNLLVLLGQHMAISVAATVLTCAVAI
MSMEG_2925|M.smegmatis_MC2_155 AVAGSLLYVEVADVSESERRALGIGNLLTLLREHMVISVAATVLTCVLAI
TH_3904|M.thermoresistible__bu AVGGALAYVHLADVSESEKRSLGVPHLLMLLRQHMEISLAATVLTCAIAI
MMAR_0033|M.marinum_M AVAGALAYVTVADVSESERRSLSVSHLLQLLREHLVISLSATVLTCVVAI
MUL_0032|M.ulcerans_Agy99 PLAERVASVAAAALTPGDQP---VGHGAHVCGGD---SGGNRIDARTEAA
Mflv_3110|M.gilvum_PYR-GCK VAGAVIFWAFNRQLTATQLENINPGNVATLIWQHLLITAAVTAIVLAIGI
MLBr_02093|M.leprae_Br4923 VVARGFYAVTRFDWWTHSLRGVMPEEFAGGVYHALYGSLVQAVVAAIMAV
. : .
Mb3782c|M.bovis_AF2122/97 PVG----LLIG--HTGRGTLLVVGAVNGLRALPTLGVLLLGVLLFGLGLG
Rv3756c|M.tuberculosis_H37Rv PVG----LLIG--HTGRGTLLVVGAVNGLRALPTLGVLLLGVLLFGLGLG
MAV_0320|M.avium_104 PVG----LLIG--HTGRGTLLVVGAVNGLRALPTLGVLLFGTLLFGLGLG
Mvan_5598|M.vanbaalenii_PYR-1 PLG----MLIG--HTGRGTFVVVTGVNALRALPTLGVLLLGVLLWGLGLI
MAB_1227|M.abscessus_ATCC_1997 PLG----IALTRGPVRRYAKTITTLVGFGQAAPAIGLIALGAVLFGIGGI
MSMEG_2925|M.smegmatis_MC2_155 PLG----IALTRGSMRRYAKPIITVAGFGQAAPAIGLIALGAVLFGIGTT
TH_3904|M.thermoresistible__bu PLG----VALTRGRFRRFATPIITVSGFGQAAPAIGLIALGAVLFGIGAV
MMAR_0033|M.marinum_M PVG----IALTRGSMRRYSKPIITVAGFGQAAPAIGLIALGAVVFGIGQL
MUL_0032|M.ulcerans_Agy99 LFE----ADHHRRQFR---------SGRAGYRPDR---AGGGRVRDRSAR
Mflv_3110|M.gilvum_PYR-GCK PLG----VLVTRPGAKVLRPLFVGIANVGQAAPAIGLLVLLFLLTAQTGF
MLBr_02093|M.leprae_Br4923 PLGSMTAVYLVEYGSGPFVRVTTFMVDVLAGVPSIVAALFIFCLWIATLG
. . * :
Mb3782c|M.bovis_AF2122/97 PP------LVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQVL
Rv3756c|M.tuberculosis_H37Rv PP------LVALMLLGIPSLLASTYAGIASVDPLVVDAARAMGMTESQVL
MAV_0320|M.avium_104 PS------LVALMLLGVPALLAGTYAGIANVEPTVVDAARAMGMTESQVL
Mvan_5598|M.vanbaalenii_PYR-1 PP------TVALMLLGIPPLLAGTYSGIANVDRDVVDAARAMGMTESRIL
MAB_1227|M.abscessus_ATCC_1997 GA------VLALTVYGALPIVANTVIGLDGVDTRLVEAARGMGMSARSTL
MSMEG_2925|M.smegmatis_MC2_155 GS------IAALTVYGALPIIANTVIGLDGVDPRLVEAARGMGMSSFSAL
TH_3904|M.thermoresistible__bu GA------VAALTVYGALPIIANTVTGLNGVDDRLIEAARGMGMPTSTTL
MMAR_0033|M.marinum_M GA------IVALTVYGAMPIIANTVTGLDGVDRRIVEAARGMGLSAFSTL
MUL_0032|M.ulcerans_Agy99 RD------RCPHRLR-RDPIIANTVTGLDGVDRRIVEAARGMGLSAFSTL
Mflv_3110|M.gilvum_PYR-GCK WIG-----VLPIALYSLLPVLSSTILGIDQVDRSLLDAGLGQGMSRRSLL
MLBr_02093|M.leprae_Br4923 FQQSAFAVSLALVLLMLPVVVRSTEEILRLVPDELREACYALGIPKWKTI
. : :: .* : * : :* . *:. :
Mb3782c|M.bovis_AF2122/97 LRVEVPNALPLMLGGLRSATLQVVA-TATVAAYASLGGLGGYLIDGIKER
Rv3756c|M.tuberculosis_H37Rv LRVEVPNALPLMLGGLRSATLQVVA-TATVAAYASLGGLGGYLIDGIKER
MAV_0320|M.avium_104 LRVEVPNALPLILGGLRSATLQVVA-TATVAAYASLGGLGRYLIDGIKER
Mvan_5598|M.vanbaalenii_PYR-1 LRVETPIAMPLILGGLRTATLQIVA-TATVAAYASLGGLGRYLIDGIKVR
MAB_1227|M.abscessus_ATCC_1997 IRVELPLALRVIVAGVRTALVLIVG-TAALASFTGAGGLGQLITTGIKLQ
MSMEG_2925|M.smegmatis_MC2_155 LKVELPLALRVIVAGVRTALVLIVG-TASLAAFTGGGGLGQLITVGIRLQ
TH_3904|M.thermoresistible__bu LRVELPLALPVIIAGVRTALVLIVG-TAALASFTGAGGLGQLITTGIKLQ
MMAR_0033|M.marinum_M RRVELPLSLPVIVAGVRTALVLIVG-TAALASFTGGGGLGQLITTGIKLQ
MUL_0032|M.ulcerans_Agy99 RRVELPLSLPVIVAGVRTALVLIVG-TAALASFTGGRGLGQLITTGIKLQ
Mflv_3110|M.gilvum_PYR-GCK LRVELPLAVPYILAGLRTSLVLAVG-TATLSFLVNAGGLGILIDTGYKLQ
MLBr_02093|M.leprae_Br4923 VRIVFPIATPGIISGVLLSIARVIGETAPVLVLVGYSRSINFDIFDGNMA
:: * : ::.*: : :. **.: .. . .
Mb3782c|M.bovis_AF2122/97 RFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKLAAVVDKPAAG
Rv3756c|M.tuberculosis_H37Rv RFHIALVGAMMVAALALTLDGLLALAGWVSVPGTGRMRKLAAVVDKPAAG
MAV_0320|M.avium_104 EFHLALVGALTVAALALVLDGLLAVAVWASVPGTGRLRRTYRPLPHRLAG
Mvan_5598|M.vanbaalenii_PYR-1 EFYLALVGALMVTALALILDAALAFAVWASVPGSGRLHR-SGSMPQPLLG
MAB_1227|M.abscessus_ATCC_1997 QPVTLVVGAILVAALALFIDWLARVVEIIAAPRGL---------------
MSMEG_2925|M.smegmatis_MC2_155 QTTTLVVGAILVASLALFIDWLARVVEMLAAPKGLG--------------
TH_3904|M.thermoresistible__bu QTVTLIVGAVLVAALALFIDWLARMVEVVAAPKGL---------------
MMAR_0033|M.marinum_M QPVTLIVGAILVAALALFIDWLARLIEMVAAPRGL---------------
MUL_0032|M.ulcerans_Agy99 QPVTLIVGAILVAALALFIDWLARLIEMVAAPRGL---------------
Mflv_3110|M.gilvum_PYR-GCK DNVTLILGSVLAVCLALLVDWLGGLAEFFLSPKGLR--------------
MLBr_02093|M.leprae_Br4923 SLPLLIYTELTNPEYAGFLRVWGAALTLIILVAGINLFGAAFRFLATRRC
: : * :
Mb3782c|M.bovis_AF2122/97 GGHALR--------------------------
Rv3756c|M.tuberculosis_H37Rv GGHALR--------------------------
MAV_0320|M.avium_104 TSYGR---------------------------
Mvan_5598|M.vanbaalenii_PYR-1 DEVALESRSRAGRRPDSEARHERGNPSPTVEA
MAB_1227|M.abscessus_ATCC_1997 --------------------------------
MSMEG_2925|M.smegmatis_MC2_155 --------------------------------
TH_3904|M.thermoresistible__bu --------------------------------
MMAR_0033|M.marinum_M --------------------------------
MUL_0032|M.ulcerans_Agy99 --------------------------------
Mflv_3110|M.gilvum_PYR-GCK --------------------------------
MLBr_02093|M.leprae_Br4923 SGCR----------------------------