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TDLTVTVGDGVAVLTLDRPDRRNAYTARMGELLSAAYRDCDEDDGVRAIVLTGAGDAFCVGADFGAQEDP FASTTAAFTASPVDPAAFELRTPVIAAVNGHAIGIGLTLALQSDIRIMAADAKYAVAQARRGVIGDCMSH WTLPHLVGGAVAADLLLTGRTFDGAEAAAMGVASRCVPAARVLDEAMVIARDIATNVAPMSAALSKRLLW DTMARGYGPRQVATLETAAHHRVMGGADAREGVAAFLERRTPRWSSSVSKEWEPLREI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3400 | - | - | 100% (269) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_1993 | - | 1e-37 | 39.02% (264) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4207 | - | 8e-29 | 35.66% (258) | enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 3e-32 | 36.55% (249) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_3132 | - | 1e-124 | 79.93% (269) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1070c | echA8 | 3e-32 | 36.55% (249) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 1e-28 | 34.54% (249) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0104 | - | 2e-77 | 57.20% (257) | enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_2974 | - | 1e-111 | 73.13% (268) | enoyl-CoA hydratase |
| M. avium 104 | MAV_4717 | - | 1e-105 | 71.27% (268) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_2229 | - | 4e-40 | 40.40% (250) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_4111 | - | 2e-39 | 39.92% (253) | PUTATIVE enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_3879 | echA12_1 | 2e-38 | 39.33% (267) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3400|M.vanbaalenii_PYR-1 --------MTDLTVTVGD-GVAVLTLDRPDRRNAYTARMGELLSAAYRDC
Mflv_3132|M.gilvum_PYR-GCK --------MTDLTVDLAD-GVAVLTLNRPRRRNAYTAEMGRLLNAAYREC
MMAR_2974|M.marinum_M --------MTDLTVSVTD-GIAILTLNRPQRRNAYTAEMGLSLSSAYRQC
MAV_4717|M.avium_104 -------MTADLTVEIDS-GVAVLTLNRPERLNAYTAAMGELLSRAYREC
MAB_0104|M.abscessus_ATCC_1997 --------MTELHEEIRD-GVAVLTLHGPSTRNSFTVELGRQLGAAYQRL
MSMEG_2229|M.smegmatis_MC2_155 MSVAETGTSDAVRYEVNDAGVAVITLNRPERLNSWGADISAGVYASFDRA
TH_4111|M.thermoresistible__bu -----------VRYEVRDPGVAVVTFDRPERLNTWARDISSGFYAAIDRA
MUL_3879|M.ulcerans_Agy99 MRMSAADAQDAVLYEATPGGVAIITFNRADRLNAWGLDLAAGFYTAIDRA
Mb1099c|M.bovis_AF2122/97 -------MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATEL
Rv1070c|M.tuberculosis_H37Rv -------MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATEL
MLBr_02402|M.leprae_Br4923 -------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKEL
:.::*:. . *: : . :
Mvan_3400|M.vanbaalenii_PYR-1 DEDDGVRAIVLTGAGDAFCVGADFG--------AQEDPFASTT--AAFTA
Mflv_3132|M.gilvum_PYR-GCK DDDDGVRAIVLTGAGDSFCAGADLA--------VPAGPFSGAD--EEFTA
MMAR_2974|M.marinum_M DDDDAVRAIVVTGAGDAFCAGADFS--------GDTNPFDAPDGGGGFTA
MAV_4717|M.avium_104 DEDDDVRVIVLTGAGRAFCAGADFS--------GGASPFDAPAGDGAFTA
MAB_0104|M.abscessus_ATCC_1997 DDDPAVRVIVLTGAPPAFCSGAQIS--------AAAETFAAPR-NPDFSA
MSMEG_2229|M.smegmatis_MC2_155 EADPAVRAIVLTGTGRGFCAGAYMG-EMA--SLGESISG--DTDVSKIVG
TH_4111|M.thermoresistible__bu DADPDVRVIVWTGNGRAFCAGADLG-SASGESLGAGLQKTDGTNVSRLVG
MUL_3879|M.ulcerans_Agy99 EADPGIRVIVLTGRGRGFCAGAYLGSADAAAGYDKTMAKAKDANLADLVG
Mb1099c|M.bovis_AF2122/97 DDDPDIGAIIITGSAKAFAAGADIK--------EMADLTFADAFTADFFA
Rv1070c|M.tuberculosis_H37Rv DDDPDIGAIIITGSAKAFAAGADIK--------EMADLTFADAFTADFFA
MLBr_02402|M.leprae_Br4923 DIDPDVGAILITGSPKVFAAGADIK--------EMASLTFTDAFDADFFS
: * : .*: ** *. ** : : .
Mvan_3400|M.vanbaalenii_PYR-1 SPVDPAAFELRTPVIAAVNGHAIGIGLTLALQSDIRIMAADAKYAVAQAR
Mflv_3132|M.gilvum_PYR-GCK SPTDPAAFELRTPVIAAVNGHAIGIGLTIALQADLRIMAIDAKYAVAQAR
MMAR_2974|M.marinum_M APIDPAAFELRTPVIAAVNGHAIGIGLTIALQADIRIMAEFAKYAVAQVR
MAV_4717|M.avium_104 SPITPAAFELRKPVIAAVNGHAVGIGLTIALQADIRIVAADAKYGVVQVR
MAB_0104|M.abscessus_ATCC_1997 SPVQPAAFELRTPVIAAVNGHAIGIGMTLALHADIRILAEEGRYAIPQVR
MSMEG_2229|M.smegmatis_MC2_155 ERHPHFLTTLRKPVIAAINGACVGIGLTHALMCDIRFAAAGAKFATAFPR
TH_4111|M.thermoresistible__bu ERHPYFLTTVRKPIIAAINGACVGIGLTHALMCDIRFAAAGAKFNTAFAR
MUL_3879|M.ulcerans_Agy99 ERPPHFVTMLRKPVIAAINGPCVGIGLTQALMCDVRFAAAGAKFAAVFAR
Mb1099c|M.bovis_AF2122/97 TWG--KLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIK
Rv1070c|M.tuberculosis_H37Rv TWG--KLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIK
MLBr_02402|M.leprae_Br4923 AWG--KLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIK
:*.* ***: * .:* * *: .*: : * .:: :
Mvan_3400|M.vanbaalenii_PYR-1 RGVIGDCMSHWTLPHLVGGAVAADLLLTGRTFDGAEAAAMGVASRCVPAA
Mflv_3132|M.gilvum_PYR-GCK RGVLGDCMSHWTLPHLVGGAVAADLLLTGRTFDGAEAGAMGIATRALPAA
MMAR_2974|M.marinum_M RGVIADCMSHWTLPHLVGSAAAADIHLTGRTFDGAEALAMGIATRTLPGP
MAV_4717|M.avium_104 RGVLPDCMAHWTLPQLTNLGVAAELLLTGRMFGGAEAAALGVANRALPAD
MAB_0104|M.abscessus_ATCC_1997 FGVAPDALAHWTLPRLVGTAVAAELLLTGASFSAQRAVETGLANRCLPAG
MSMEG_2229|M.smegmatis_MC2_155 RGLIGEYGITWILPRLAGWGAAADLLLSGRTFLAEEALQLGLVKEVVEPE
TH_4111|M.thermoresistible__bu RGLIAEYGISWILPRLAGWGVATELLLSGRTFRAEEAHRLGLVHDVVPAE
MUL_3879|M.ulcerans_Agy99 RGLIAEFGISWILPRLTSWAVALDLLLSGRIFLAEEAAQLGLVKEVVTPE
Mb1099c|M.bovis_AF2122/97 LGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPAD
Rv1070c|M.tuberculosis_H37Rv LGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPAD
MLBr_02402|M.leprae_Br4923 LGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLAD
*: *.: . . * :: *:* : . .* *:. :
Mvan_3400|M.vanbaalenii_PYR-1 RVLDEAMVIARDIATNVAPMSAALSKRLLWDTMARGYGPRQVATLETAAH
Mflv_3132|M.gilvum_PYR-GCK EVLDSALATAADIATNVAPMSAALSKRLLWDTMSRGYTARQVARLETELH
MMAR_2974|M.marinum_M HVLGHAMAVARDIAANTAPMSVALSKRLLWDTLINGYTPRQVAELETQLH
MAV_4717|M.avium_104 RVLDEAMALARDIAVNVAPMSAALCKRLLWDSAINRYPPRQVAALETLLH
MAB_0104|M.abscessus_ATCC_1997 KVLGAALRMAHDIATNVAPESAALTKRLLWDAQMTGMSAAEVAARETADH
MSMEG_2229|M.smegmatis_MC2_155 NLLTRALEYAEDLARNCSPASMAVIKRQLYGDATD--VVTDVSDRAVTLM
TH_4111|M.thermoresistible__bu ELTEHTLAYAEDIARNCAPASLAVIKQQLYGDAMD--GVVDVSARAEKLM
MUL_3879|M.ulcerans_Agy99 QLMPRALEYAEDIARYCSPSSMAVIKRQVYGDATR--DVVEATSHAEVLL
Mb1099c|M.bovis_AF2122/97 DLLTEARATATTIS-QMSASAARMAKEAVNRAFES--SLSEGLLYERRLF
Rv1070c|M.tuberculosis_H37Rv DLLTEARATATTIS-QMSASAARMAKEAVNRAFES--SLSEGLLYERRLF
MLBr_02402|M.leprae_Br4923 DLLPEAKAVATTIS-QMSRSATRMAKEAVNRSFES--TLAEGLLHERRLF
: : * :: : : : *. : :
Mvan_3400|M.vanbaalenii_PYR-1 HRVMGGADAREGVAAFLERRTPRWSSSVSKEWEPLREI----------
Mflv_3132|M.gilvum_PYR-GCK HRVMGGADAREGVAAFLERRTPRWSASVAQEWEPVPHVDREGSGRSDS
MMAR_2974|M.marinum_M RRVMGSADAREGVEAFLQHRAPRWSASVSSAWKPLPAPDHREQP----
MAV_4717|M.avium_104 ERVMGGADAAEGVAAFREHRAPRFTARLSSEWEPLPEP----------
MAB_0104|M.abscessus_ATCC_1997 LRLMGSQDAAEGPRAFIDGRPPRWAGQR--------------------
MSMEG_2229|M.smegmatis_MC2_155 HESMVRPDLIEGITAFFEKRPPNFPPLAAE------------------
TH_4111|M.thermoresistible__bu HESLRRPDVIEGITSFIEKRQPAFPPLAPSDP----------------
MUL_3879|M.ulcerans_Agy99 REAMPRPDVIEGIVSFLEKRPPQFPSLTSSER----------------
Mb1099c|M.bovis_AF2122/97 HSAFATEDQSEGMAAFIEKRAPQFTHR---------------------
Rv1070c|M.tuberculosis_H37Rv HSAFATEDQSEGMAAFIEKRAPQFTHR---------------------
MLBr_02402|M.leprae_Br4923 HSTFVTDDQSEGMAAFIEKRAPQFTHR---------------------
: * ** :* : * * :.