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M. thermoresistible (build 8) TH_4111 (-)

annotation: enoyl-CoA hydratase
coordinates: 2338109 - 2338915
length: 269

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4111--100% (269)enoyl-CoA hydratase
M. thermoresistible (build 8)TH_2798-3e-3438.52% (257) PUTATIVE Enoyl-CoA hydratase
M. thermoresistible (build 8)TH_2877-5e-3132.31% (260) PUTATIVE putative enoyl-CoA hydratase/isomerase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1507echA127e-3034.77% (256) enoyl-CoA hydratase
M. gilvum PYR-GCKMflv_4351-1e-10066.67% (264) enoyl-CoA hydratase
M. tuberculosis H37RvRv1472echA121e-2934.77% (256) enoyl-CoA hydratase
M. leprae Br4923MLBr_01241-1e-2733.33% (252) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_0834-6e-4042.17% (230) putative enoyl-CoA hydratase/isomerase
M. marinum MMMAR_4015echA12_18e-9363.10% (271) enoyl-CoA hydratase, EchA12_1
M. avium 104MAV_1590-1e-10673.86% (264) enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_2229-1e-10371.21% (264) enoyl-CoA hydratase
M. ulcerans Agy99MUL_3879echA12_18e-9262.36% (271) enoyl-CoA hydratase
M. vanbaalenii PYR-1Mvan_1993-1e-10467.38% (279) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4351|M.gilvum_PYR-GCK          ----MSAVDRAVDR---RAEPVLFDLHDSGVAVLTLNRPDRMNSWGGGLA
Mvan_1993|M.vanbaalenii_PYR-1       ----MSAVDRAAEPGIADTEPVLFDMHDSGVAVLTLNRPERMNSWGGGLA
MAV_1590|M.avium_104                ----MSAADHVVTD-----EAVLYQTTETGVAVVTFNRPERLNAWGPDIS
MSMEG_2229|M.smegmatis_MC2_155      ----MSVAETGTSD------AVRYEVNDAGVAVITLNRPERLNSWGADIS
TH_4111|M.thermoresistible__bu      ---------------------VRYEVRDPGVAVVTFDRPERLNTWARDIS
MMAR_4015|M.marinum_M               ----MSAAD--AQD------AVLYEATPGGVAIITFNRADRLNAWGPDLA
MUL_3879|M.ulcerans_Agy99           --MRMSAAD--AQD------AVLYEATPGGVAIITFNRADRLNAWGLDLA
Mb1507|M.bovis_AF2122/97            MPHRCAAQVVAG--YRSTVSLVLVEHPRPEIAQITLNRPERMNSMAFDVM
Rv1472|M.tuberculosis_H37Rv         MPHRCAAQVVAG--YRSTVSLVLVEHPRPEIAQITLNRPERMNSMAFDVM
MLBr_01241|M.leprae_Br4923          MSQTDASCTIAELPYRSVTDLVVLDFPRPEVALITLNRPGRMNSMALDLM
MAB_0834|M.abscessus_ATCC_1997      --------------------MIRVEPREHGILVVTIDRPERRNALDPQTV
                                                         :  :     :  :*::*. * *:      

Mflv_4351|M.gilvum_PYR-GCK          RAFYECIDRAEADPDVRVIVLTGNGRAFCAGADMGDLD--SISGASDS--
Mvan_1993|M.vanbaalenii_PYR-1       QAFYRCIDRAEADPHVRVIVLTGNGRAFCAGADMGDLD--SISAAGDTGR
MAV_1590|M.avium_104                SGFYACIDRAEADPAVRVIVLTGAGRGFCAGANLGGAG--SIDAKLGD--
MSMEG_2229|M.smegmatis_MC2_155      AGVYASFDRAEADPAVRAIVLTGTGRGFCAGAYMGEMA--SLGESISG--
TH_4111|M.thermoresistible__bu      SGFYAAIDRADADPDVRVIVWTGNGRAFCAGADLGSASGESLGAGLQKT-
MMAR_4015|M.marinum_M               AGFYAAIDRAEADPGIRVIVLTGRGRGFCAGAYLGSAD---AAAGYDKT-
MUL_3879|M.ulcerans_Agy99           AGFYTAIDRAEADPGIRVIVLTGRGRGFCAGAYLGSAD---AAAGYDKT-
Mb1507|M.bovis_AF2122/97            VPLKEALAQVSYDNSVRVVVLTGAGRGFSSGADHK-------SAGVVPHV
Rv1472|M.tuberculosis_H37Rv         VPLKEALAQVSYDNSVRVVVLTGAGRGFSPGADHK-------SAGVVPHV
MLBr_01241|M.leprae_Br4923          KSLKQVLKRITYDHSVRVVVLTGAGRGFCSGADQK-------FTAPVPQV
MAB_0834|M.abscessus_ATCC_1997      AELHAVIESIDGDPKVRVVVLTAVGASFCAGADLKSLPSDFTSAGVTSTA
                                      .   :     *  :*.:* *. * .*..**                  

Mflv_4351|M.gilvum_PYR-GCK          ----------SDTDVTQLVGERHPHFVTQLRTPIIAAINGACAGIGLTQA
Mvan_1993|M.vanbaalenii_PYR-1       GERSDGESGLADTDVSQLVGERHPHFLTQLRKPLIAAINGACAGIGLTHA
MAV_1590|M.avium_104                ----------GDTDVTALVGDRHPHFLTALRKPIIAAINGACVGIGLTHA
MSMEG_2229|M.smegmatis_MC2_155      -----------DTDVSKIVGERHPHFLTTLRKPVIAAINGACVGIGLTHA
TH_4111|M.thermoresistible__bu      ----------DGTNVSRLVGERHPYFLTTVRKPIIAAINGACVGIGLTHA
MMAR_4015|M.marinum_M               ------MAKAKDANLADLVGERPPHFVTMLRKPVIAAINGPCVGIGLTQA
MUL_3879|M.ulcerans_Agy99           ------MAKAKDANLADLVGERPPHFVTMLRKPVIAAINGPCVGIGLTQA
Mb1507|M.bovis_AF2122/97            ENLTRP----TYALRSMELLDDVILMLRRLHQPVIAAVNGPAIGGGLCLA
Rv1472|M.tuberculosis_H37Rv         ENLTRP----TYALRSMELLDDVILMLRRLHQPVIAAVNGPAIGGGLCLA
MLBr_01241|M.leprae_Br4923          EGLTQP----VRALRAMELLEEVILALRRLHQPVIAAINGPAIGGGLCLA
MAB_0834|M.abscessus_ATCC_1997      ALLAATDSELVRTLAAQELMASLFERIHRMRQPVIAAVNGHAIGGGFALA
                                                :  :  :       :  :: *:***:** . * *:  *

Mflv_4351|M.gilvum_PYR-GCK          LMCDVRFAAAGAKFTTAFSRRGLIA-EYGISWILPRIVGWGAAQDLLLSG
Mvan_1993|M.vanbaalenii_PYR-1       LMCDVRFAAAGAKFTTAFARRGLIA-EYGISWILPRIVGWSAAQDLLLSG
MAV_1590|M.avium_104                LMCDVRFAAAGAKFATAFTRRGLIA-EYGITWILPRLAGWGAAMDLLLSG
MSMEG_2229|M.smegmatis_MC2_155      LMCDIRFAAAGAKFATAFPRRGLIG-EYGITWILPRLAGWGAAADLLLSG
TH_4111|M.thermoresistible__bu      LMCDIRFAAAGAKFNTAFARRGLIA-EYGISWILPRLAGWGVATELLLSG
MMAR_4015|M.marinum_M               LMCDVRFAAAGAKFAAVFARRGLIA-EFGISWILPRLTSWAVALDLLLSG
MUL_3879|M.ulcerans_Agy99           LMCDVRFAAAGAKFAAVFARRGLIA-EFGISWILPRLTSWAVALDLLLSG
Mb1507|M.bovis_AF2122/97            LAADIRVASSSAYFRAAGINNGLTASELGLSYLLPRAIGSSRAFEIMLTG
Rv1472|M.tuberculosis_H37Rv         LAADIRVASSSAYFRAAGINNGLTASELGLSYLLPRAIGSSRAFEIMLTG
MLBr_01241|M.leprae_Br4923          LAADVRVASTRAYFRAAGINNGLSASELGLSYLLPRAVGSSRAFEIMLSG
MAB_0834|M.abscessus_ATCC_1997      LACDIRFASPAASFGAVFIRHGVSNCDMGTSYHLPRLVGAARAAELMLTG
                                    * .*:*.*:. * * :.  ..*:   : * :: ***  . . * :::*:*

Mflv_4351|M.gilvum_PYR-GCK          RTFYAEEAKSLGLVNDVVAPDELMAHTLSYAEDMARNCAPSSMAVIKRQL
Mvan_1993|M.vanbaalenii_PYR-1       RTFYAEEANELGLVNQVVAPDELMAHTLAYAEDMARNCAPSSLAVIKRQI
MAV_1590|M.avium_104                RTFFAEEAAKLGLVNEIVAPDELMARALTYADDIARNCSPASLAVIKRQA
MSMEG_2229|M.smegmatis_MC2_155      RTFLAEEALQLGLVKEVVEPENLLTRALEYAEDLARNCSPASMAVIKRQL
TH_4111|M.thermoresistible__bu      RTFRAEEAHRLGLVHDVVPAEELTEHTLAYAEDIARNCAPASLAVIKQQL
MMAR_4015|M.marinum_M               RTFLAEEAAQLGLVKEVVTPEQLMPRALEYAEDIARYCSPSSMAVIKRQV
MUL_3879|M.ulcerans_Agy99           RIFLAEEAAQLGLVKEVVTPEQLMPRALEYAEDIARYCSPSSMAVIKRQV
Mb1507|M.bovis_AF2122/97            RDVSAEEAERIGLVSRQVPDEQLLDACYAIAARMAGFS-RPGIELTKRTL
Rv1472|M.tuberculosis_H37Rv         RDVSAEEAERIGLVSRQVPDEQLLDACYAIAARMAGFS-RPGIELTKRTL
MLBr_01241|M.leprae_Br4923          RDVGAEEAEQIGLVSYRVSDDRLLDTCYSIAARMATFS-RSGTELTKRAL
MAB_0834|M.abscessus_ATCC_1997      RVFDAQEAYRMGLVFDVVPAEELLDAALSKAREIAVHS-PLAVWMTKETM
                                    * . *:**  :***   *  :.*       *  :*  .   .  : *.  

Mflv_4351|M.gilvum_PYR-GCK          HK--DALRNLHDASAEAETLMHESMLRPDFIEGITAFFEKRPPSFPPLST
Mvan_1993|M.vanbaalenii_PYR-1       YR--DALRNLSDASADAEKLMHESMQRPDFIEGITAFFEKRQPSFPPL--
MAV_1590|M.avium_104                YD--DALRDVVDVSARAETLMHESLQRPDVIEGITSFLEKRPPRFPPLAT
MSMEG_2229|M.smegmatis_MC2_155      YG--DATDVVTDVSDRAVTLMHESMVRPDLIEGITAFFEKRPPNFPPLAA
TH_4111|M.thermoresistible__bu      YG--DAMDGVVDVSARAEKLMHESLRRPDVIEGITSFIEKRQPAFPPLAP
MMAR_4015|M.marinum_M               YG--DATRDVVEATSHAEVLLREAMPRPDVIEGIVSFLEKRPPQFPSLTS
MUL_3879|M.ulcerans_Agy99           YG--DATRDVVEATSHAEVLLREAMPRPDVIEGIVSFLEKRPPQFPSLTS
Mb1507|M.bovis_AF2122/97            WSGLDAASLEAHMQAEGLGQLFVRLLTANFEEAVAARAEQRAPVFTDDT-
Rv1472|M.tuberculosis_H37Rv         WSGLDAASLEAHMQAEGLGQLFVRLLTANFEEAVAARAEQRAPVFTDDT-
MLBr_01241|M.leprae_Br4923          WGGLDAASLDKHMQSESLAQLFIALHTSNFEEAAAPCTEKRPTVLVDARG
MAB_0834|M.abscessus_ATCC_1997      WQTVDAPSLRHALDLENRTQVMCT-ATGELRRSFDAFREGRG--------
                                        **              :       :. ..  .  * *         

Mflv_4351|M.gilvum_PYR-GCK          QKEETP
Mvan_1993|M.vanbaalenii_PYR-1       -KEETP
MAV_1590|M.avium_104                ------
MSMEG_2229|M.smegmatis_MC2_155      E-----
TH_4111|M.thermoresistible__bu      SDP---
MMAR_4015|M.marinum_M               SER---
MUL_3879|M.ulcerans_Agy99           SER---
Mb1507|M.bovis_AF2122/97            ------
Rv1472|M.tuberculosis_H37Rv         ------
MLBr_01241|M.leprae_Br4923          CATSPG
MAB_0834|M.abscessus_ATCC_1997      ------