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M. avium 104 MAV_4717 (-)

TADLTVEIDSGVAVLTLNRPERLNAYTAAMGELLSRAYRECDEDDDVRVIVLTGAGRAFCAGADFSGGAS
PFDAPAGDGAFTASPITPAAFELRKPVIAAVNGHAVGIGLTIALQADIRIVAADAKYGVVQVRRGVLPDC
MAHWTLPQLTNLGVAAELLLTGRMFGGAEAAALGVANRALPADRVLDEAMALARDIAVNVAPMSAALCKR
LLWDSAINRYPPRQVAALETLLHERVMGGADAAEGVAAFREHRAPRFTARLSSEWEPLPEP*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_4717	-	-	100% (272)	enoyl-CoA hydratase/isomerase family protein
M. avium 104	MAV_1590	-	5e-48	44.09% (254)	enoyl-CoA hydratase
M. avium 104	MAV_1060	-	5e-34	37.00% (273)	enoyl-CoA hydratase/isomerase family protein

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	Mb1099c	echA8	7e-35	37.40% (262)	enoyl-CoA hydratase
M. gilvum PYR-GCK	Mflv_3132	-	1e-101	70.04% (267)	enoyl-CoA hydratase/isomerase
M. tuberculosis H37Rv	Rv1070c	echA8	7e-35	37.40% (262)	enoyl-CoA hydratase
M. leprae Br4923	MLBr_02402	-	2e-33	37.80% (254)	enoyl-CoA hydratase
M. abscessus ATCC 19977	MAB_0104	-	3e-73	55.81% (258)	enoyl-CoA hydratase/isomerase
M. marinum M	MMAR_2974	-	1e-106	69.89% (269)	enoyl-CoA hydratase
M. smegmatis MC2 155	MSMEG_2229	-	4e-43	42.46% (252)	enoyl-CoA hydratase
M. thermoresistible (build 8)	TH_4111	-	6e-45	42.80% (257)	PUTATIVE enoyl-CoA hydratase
M. ulcerans Agy99	MUL_3879	echA12_1	3e-41	41.44% (263)	enoyl-CoA hydratase
M. vanbaalenii PYR-1	Mvan_3400	-	1e-105	71.27% (268)	enoyl-CoA hydratase/isomerase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3132|M.gilvum_PYR-GCK          --------MTDLTVDLAD-GVAVLTLNRPRRRNAYTAEMGRLLNAAYREC
Mvan_3400|M.vanbaalenii_PYR-1       --------MTDLTVTVGD-GVAVLTLDRPDRRNAYTARMGELLSAAYRDC
MMAR_2974|M.marinum_M               --------MTDLTVSVTD-GIAILTLNRPQRRNAYTAEMGLSLSSAYRQC
MAV_4717|M.avium_104                -------MTADLTVEIDS-GVAVLTLNRPERLNAYTAAMGELLSRAYREC
MAB_0104|M.abscessus_ATCC_1997      --------MTELHEEIRD-GVAVLTLHGPSTRNSFTVELGRQLGAAYQRL
MSMEG_2229|M.smegmatis_MC2_155      MSVAETGTSDAVRYEVNDAGVAVITLNRPERLNSWGADISAGVYASFDRA
TH_4111|M.thermoresistible__bu      -----------VRYEVRDPGVAVVTFDRPERLNTWARDISSGFYAAIDRA
MUL_3879|M.ulcerans_Agy99           MRMSAADAQDAVLYEATPGGVAIITFNRADRLNAWGLDLAAGFYTAIDRA
Mb1099c|M.bovis_AF2122/97           -------MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATEL
Rv1070c|M.tuberculosis_H37Rv        -------MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATEL
MLBr_02402|M.leprae_Br4923          -------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKEL
                                                        :.::*:. .   *:    :   .  :    

Mflv_3132|M.gilvum_PYR-GCK          DDDDGVRAIVLTGAGDSFCAGADLA--------VPAGPFSGAD--EEFTA
Mvan_3400|M.vanbaalenii_PYR-1       DEDDGVRAIVLTGAGDAFCVGADFG--------AQEDPFASTT--AAFTA
MMAR_2974|M.marinum_M               DDDDAVRAIVVTGAGDAFCAGADFS--------GDTNPFDAPDGGGGFTA
MAV_4717|M.avium_104                DEDDDVRVIVLTGAGRAFCAGADFS--------GGASPFDAPAGDGAFTA
MAB_0104|M.abscessus_ATCC_1997      DDDPAVRVIVLTGAPPAFCSGAQIS--------AAAETFAAPR-NPDFSA
MSMEG_2229|M.smegmatis_MC2_155      EADPAVRAIVLTGTGRGFCAGAYMG-EMA--SLGESISG--DTDVSKIVG
TH_4111|M.thermoresistible__bu      DADPDVRVIVWTGNGRAFCAGADLG-SASGESLGAGLQKTDGTNVSRLVG
MUL_3879|M.ulcerans_Agy99           EADPGIRVIVLTGRGRGFCAGAYLGSADAAAGYDKTMAKAKDANLADLVG
Mb1099c|M.bovis_AF2122/97           DDDPDIGAIIITGSAKAFAAGADIK--------EMADLTFADAFTADFFA
Rv1070c|M.tuberculosis_H37Rv        DDDPDIGAIIITGSAKAFAAGADIK--------EMADLTFADAFTADFFA
MLBr_02402|M.leprae_Br4923          DIDPDVGAILITGSPKVFAAGADIK--------EMASLTFTDAFDADFFS
                                    : *  : .*: **    *. ** :                       : .

Mflv_3132|M.gilvum_PYR-GCK          SPTDPAAFELRTPVIAAVNGHAIGIGLTIALQADLRIMAIDAKYAVAQAR
Mvan_3400|M.vanbaalenii_PYR-1       SPVDPAAFELRTPVIAAVNGHAIGIGLTLALQSDIRIMAADAKYAVAQAR
MMAR_2974|M.marinum_M               APIDPAAFELRTPVIAAVNGHAIGIGLTIALQADIRIMAEFAKYAVAQVR
MAV_4717|M.avium_104                SPITPAAFELRKPVIAAVNGHAVGIGLTIALQADIRIVAADAKYGVVQVR
MAB_0104|M.abscessus_ATCC_1997      SPVQPAAFELRTPVIAAVNGHAIGIGMTLALHADIRILAEEGRYAIPQVR
MSMEG_2229|M.smegmatis_MC2_155      ERHPHFLTTLRKPVIAAINGACVGIGLTHALMCDIRFAAAGAKFATAFPR
TH_4111|M.thermoresistible__bu      ERHPYFLTTVRKPIIAAINGACVGIGLTHALMCDIRFAAAGAKFNTAFAR
MUL_3879|M.ulcerans_Agy99           ERPPHFVTMLRKPVIAAINGPCVGIGLTQALMCDVRFAAAGAKFAAVFAR
Mb1099c|M.bovis_AF2122/97           TWG--KLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIK
Rv1070c|M.tuberculosis_H37Rv        TWG--KLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIK
MLBr_02402|M.leprae_Br4923          AWG--KLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIK
                                             :*.* ***: * .:* *   *: .*: : *  .::     :

Mflv_3132|M.gilvum_PYR-GCK          RGVLGDCMSHWTLPHLVGGAVAADLLLTGRTFDGAEAGAMGIATRALPAA
Mvan_3400|M.vanbaalenii_PYR-1       RGVIGDCMSHWTLPHLVGGAVAADLLLTGRTFDGAEAAAMGVASRCVPAA
MMAR_2974|M.marinum_M               RGVIADCMSHWTLPHLVGSAAAADIHLTGRTFDGAEALAMGIATRTLPGP
MAV_4717|M.avium_104                RGVLPDCMAHWTLPQLTNLGVAAELLLTGRMFGGAEAAALGVANRALPAD
MAB_0104|M.abscessus_ATCC_1997      FGVAPDALAHWTLPRLVGTAVAAELLLTGASFSAQRAVETGLANRCLPAG
MSMEG_2229|M.smegmatis_MC2_155      RGLIGEYGITWILPRLAGWGAAADLLLSGRTFLAEEALQLGLVKEVVEPE
TH_4111|M.thermoresistible__bu      RGLIAEYGISWILPRLAGWGVATELLLSGRTFRAEEAHRLGLVHDVVPAE
MUL_3879|M.ulcerans_Agy99           RGLIAEFGISWILPRLTSWAVALDLLLSGRIFLAEEAAQLGLVKEVVTPE
Mb1099c|M.bovis_AF2122/97           LGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPAD
Rv1070c|M.tuberculosis_H37Rv        LGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPAD
MLBr_02402|M.leprae_Br4923          LGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLAD
                                     *:         *.:  . . * :: *:*  : . .*   *:.   :   

Mflv_3132|M.gilvum_PYR-GCK          EVLDSALATAADIATNVAPMSAALSKRLLWDTMSRGYTARQVARLETELH
Mvan_3400|M.vanbaalenii_PYR-1       RVLDEAMVIARDIATNVAPMSAALSKRLLWDTMARGYGPRQVATLETAAH
MMAR_2974|M.marinum_M               HVLGHAMAVARDIAANTAPMSVALSKRLLWDTLINGYTPRQVAELETQLH
MAV_4717|M.avium_104                RVLDEAMALARDIAVNVAPMSAALCKRLLWDSAINRYPPRQVAALETLLH
MAB_0104|M.abscessus_ATCC_1997      KVLGAALRMAHDIATNVAPESAALTKRLLWDAQMTGMSAAEVAARETADH
MSMEG_2229|M.smegmatis_MC2_155      NLLTRALEYAEDLARNCSPASMAVIKRQLYGDATD--VVTDVSDRAVTLM
TH_4111|M.thermoresistible__bu      ELTEHTLAYAEDIARNCAPASLAVIKQQLYGDAMD--GVVDVSARAEKLM
MUL_3879|M.ulcerans_Agy99           QLMPRALEYAEDIARYCSPSSMAVIKRQVYGDATR--DVVEATSHAEVLL
Mb1099c|M.bovis_AF2122/97           DLLTEARATATTIS-QMSASAARMAKEAVNRAFES--SLSEGLLYERRLF
Rv1070c|M.tuberculosis_H37Rv        DLLTEARATATTIS-QMSASAARMAKEAVNRAFES--SLSEGLLYERRLF
MLBr_02402|M.leprae_Br4923          DLLPEAKAVATTIS-QMSRSATRMAKEAVNRSFES--TLAEGLLHERRLF
                                     :   :   *  ::   :  :  : *. :           :         

Mflv_3132|M.gilvum_PYR-GCK          HRVMGGADAREGVAAFLERRTPRWSASVAQEWEPVPHVDREGSGRSDS
Mvan_3400|M.vanbaalenii_PYR-1       HRVMGGADAREGVAAFLERRTPRWSSSVSKEWEPLREI----------
MMAR_2974|M.marinum_M               RRVMGSADAREGVEAFLQHRAPRWSASVSSAWKPLPAPDHREQP----
MAV_4717|M.avium_104                ERVMGGADAAEGVAAFREHRAPRFTARLSSEWEPLPEP----------
MAB_0104|M.abscessus_ATCC_1997      LRLMGSQDAAEGPRAFIDGRPPRWAGQR--------------------
MSMEG_2229|M.smegmatis_MC2_155      HESMVRPDLIEGITAFFEKRPPNFPPLAAE------------------
TH_4111|M.thermoresistible__bu      HESLRRPDVIEGITSFIEKRQPAFPPLAPSDP----------------
MUL_3879|M.ulcerans_Agy99           REAMPRPDVIEGIVSFLEKRPPQFPSLTSSER----------------
Mb1099c|M.bovis_AF2122/97           HSAFATEDQSEGMAAFIEKRAPQFTHR---------------------
Rv1070c|M.tuberculosis_H37Rv        HSAFATEDQSEGMAAFIEKRAPQFTHR---------------------
MLBr_02402|M.leprae_Br4923          HSTFVTDDQSEGMAAFIEKRAPQFTHR---------------------
                                       :   *  **  :* : * * :.