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VTELHEEIRDGVAVLTLHGPSTRNSFTVELGRQLGAAYQRLDDDPAVRVIVLTGAPPAFCSGAQISAAAE TFAAPRNPDFSASPVQPAAFELRTPVIAAVNGHAIGIGMTLALHADIRILAEEGRYAIPQVRFGVAPDAL AHWTLPRLVGTAVAAELLLTGASFSAQRAVETGLANRCLPAGKVLGAALRMAHDIATNVAPESAALTKRL LWDAQMTGMSAAEVAARETADHLRLMGSQDAAEGPRAFIDGRPPRWAGQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0104 | - | - | 100% (260) | enoyl-CoA hydratase/isomerase |
| M. abscessus ATCC 19977 | MAB_4164 | - | 9e-33 | 33.98% (256) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_4588c | - | 2e-30 | 32.55% (255) | enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 2e-29 | 32.93% (246) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_3132 | - | 8e-78 | 57.20% (257) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv0222 | echA1 | 1e-30 | 32.82% (259) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 1e-26 | 32.00% (250) | enoyl-CoA hydratase |
| M. marinum M | MMAR_2974 | - | 9e-76 | 54.65% (258) | enoyl-CoA hydratase |
| M. avium 104 | MAV_4717 | - | 2e-73 | 55.81% (258) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_2229 | - | 3e-34 | 36.36% (264) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_4111 | - | 4e-34 | 36.98% (265) | PUTATIVE enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_1114 | echA1 | 8e-33 | 35.14% (259) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_3400 | - | 3e-77 | 57.20% (257) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3132|M.gilvum_PYR-GCK ----------MTDLTVDLAD-GVAVLTLNRPRRRNAYTAEMGRLLNAAYR
Mvan_3400|M.vanbaalenii_PYR-1 ----------MTDLTVTVGD-GVAVLTLDRPDRRNAYTARMGELLSAAYR
MMAR_2974|M.marinum_M ----------MTDLTVSVTD-GIAILTLNRPQRRNAYTAEMGLSLSSAYR
MAV_4717|M.avium_104 ---------MTADLTVEIDS-GVAVLTLNRPERLNAYTAAMGELLSRAYR
MAB_0104|M.abscessus_ATCC_1997 ----------MTELHEEIRD-GVAVLTLHGPSTRNSFTVELGRQLGAAYQ
MSMEG_2229|M.smegmatis_MC2_155 --MSVAETGTSDAVRYEVNDAGVAVITLNRPERLNSWGADISAGVYASFD
TH_4111|M.thermoresistible__bu -------------VRYEVRDPGVAVVTFDRPERLNTWARDISSGFYAAID
Mb1099c|M.bovis_AF2122/97 --------MTYETILVERDQ-RVGIITLNRPQALNALNSQVMNEVTSAAT
MLBr_02402|M.leprae_Br4923 --------MKYDTILVDGYQ-RVGIITLNRPQALNALNSQMMNEITNAAK
Rv0222|M.tuberculosis_H37Rv MSSESDAANTEPEVLVEQRD-RILIITINRPKAKNAVNAAVSRGLADAMD
MUL_1114|M.ulcerans_Agy99 MSELN--GDTEPEVLVEQRD-RILIITINRPKAKNSVNAAVSRALADAMD
: . : ::*:. * *: : . :
Mflv_3132|M.gilvum_PYR-GCK ECDDDDGVRAIVLTGAGDSFCAGADLAVPA--GPFSGAD--EEFTASPTD
Mvan_3400|M.vanbaalenii_PYR-1 DCDEDDGVRAIVLTGAGDAFCVGADFGAQE--DPFASTT--AAFTASPVD
MMAR_2974|M.marinum_M QCDDDDAVRAIVVTGAGDAFCAGADFSGDT--NPFDAPDGGGGFTAAPID
MAV_4717|M.avium_104 ECDEDDDVRVIVLTGAGRAFCAGADFSGGA--SPFDAPAGDGAFTASPIT
MAB_0104|M.abscessus_ATCC_1997 RLDDDPAVRVIVLTGAPPAFCSGAQISAAA--ETFAAPR-NPDFSASPVQ
MSMEG_2229|M.smegmatis_MC2_155 RAEADPAVRAIVLTGTGRGFCAGAYMGEMA--SLGESISG--DTDVSKIV
TH_4111|M.thermoresistible__bu RADADPDVRVIVWTGNGRAFCAGADLGSASGESLGAGLQKTDGTNVSRLV
Mb1099c|M.bovis_AF2122/97 ELDDDPDIGAIIITGSAKAFAAGADIKEMADLTFADAFTADFFATWGKLA
MLBr_02402|M.leprae_Br4923 ELDIDPDVGAILITGSPKVFAAGADIKEMASLTFTDAFDADFFSAWGKLA
Rv0222|M.tuberculosis_H37Rv QLDGDAGLSVAILTGGGGSFCAGMDLKAFARGENVVVEGRGLGFTE---R
MUL_1114|M.ulcerans_Agy99 RLDADAGLSVGILTGAGGSFCAGMDLKAFARGENVVVEGRGLGFTE---R
: * : . : ** *. * :
Mflv_3132|M.gilvum_PYR-GCK PAAF-----ELRTPVIAAVNGHAIGIGLTIALQADLRIMAIDAKYAVAQA
Mvan_3400|M.vanbaalenii_PYR-1 PAAF-----ELRTPVIAAVNGHAIGIGLTLALQSDIRIMAADAKYAVAQA
MMAR_2974|M.marinum_M PAAF-----ELRTPVIAAVNGHAIGIGLTIALQADIRIMAEFAKYAVAQV
MAV_4717|M.avium_104 PAAF-----ELRKPVIAAVNGHAVGIGLTIALQADIRIVAADAKYGVVQV
MAB_0104|M.abscessus_ATCC_1997 PAAF-----ELRTPVIAAVNGHAIGIGMTLALHADIRILAEEGRYAIPQV
MSMEG_2229|M.smegmatis_MC2_155 GERHPHFLTTLRKPVIAAINGACVGIGLTHALMCDIRFAAAGAKFATAFP
TH_4111|M.thermoresistible__bu GERHPYFLTTVRKPIIAAINGACVGIGLTHALMCDIRFAAAGAKFNTAFA
Mb1099c|M.bovis_AF2122/97 AVRT---------PTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEI
MLBr_02402|M.leprae_Br4923 AVRT---------PMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEI
Rv0222|M.tuberculosis_H37Rv PPTK---------PLIAAVEGYALAGGTELALAADLIVAARDSAFGIPEV
MUL_1114|M.ulcerans_Agy99 PPAK---------PLIAAVEGYALAGGTELALATDLIVAARDSAFGIPEV
* ***: * .:. * *: *: . * . :
Mflv_3132|M.gilvum_PYR-GCK RRGVLGDCMSHWTLPHLVGGAVAADLLLTGRTFDGAEAGAMGIATRALPA
Mvan_3400|M.vanbaalenii_PYR-1 RRGVIGDCMSHWTLPHLVGGAVAADLLLTGRTFDGAEAAAMGVASRCVPA
MMAR_2974|M.marinum_M RRGVIADCMSHWTLPHLVGSAAAADIHLTGRTFDGAEALAMGIATRTLPG
MAV_4717|M.avium_104 RRGVLPDCMAHWTLPQLTNLGVAAELLLTGRMFGGAEAAALGVANRALPA
MAB_0104|M.abscessus_ATCC_1997 RFGVAPDALAHWTLPRLVGTAVAAELLLTGASFSAQRAVETGLANRCLPA
MSMEG_2229|M.smegmatis_MC2_155 RRGLIGEYGITWILPRLAGWGAAADLLLSGRTFLAEEALQLGLVKEVVEP
TH_4111|M.thermoresistible__bu RRGLIAEYGISWILPRLAGWGVATELLLSGRTFRAEEAHRLGLVHDVVPA
Mb1099c|M.bovis_AF2122/97 KLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPA
MLBr_02402|M.leprae_Br4923 KLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLA
Rv0222|M.tuberculosis_H37Rv KRGLVAGGGGLLRLPERIPYAIAMELALTGDNLPAERAHELGLVNVLAEP
MUL_1114|M.ulcerans_Agy99 KRGLAAGGGGLLRLPERIPYAIAMELALTGDNLSAERAHALGMVNVLAEP
: *: *.. . * :: *:* : . .* *:.
Mflv_3132|M.gilvum_PYR-GCK AEVLDSALATAADIATNVAPMSAALSKRLLWDTMSRGYTARQVARLETEL
Mvan_3400|M.vanbaalenii_PYR-1 ARVLDEAMVIARDIATNVAPMSAALSKRLLWDTMARGYGPRQVATLETAA
MMAR_2974|M.marinum_M PHVLGHAMAVARDIAANTAPMSVALSKRLLWDTLINGYTPRQVAELETQL
MAV_4717|M.avium_104 DRVLDEAMALARDIAVNVAPMSAALCKRLLWDSAINRYPPRQVAALETLL
MAB_0104|M.abscessus_ATCC_1997 GKVLGAALRMAHDIATNVAPESAALTKRLLWDAQMTGMSAAEVAARETAD
MSMEG_2229|M.smegmatis_MC2_155 ENLLTRALEYAEDLARNCSPASMAVIKRQLYGDATDVVT--DVSDRAVTL
TH_4111|M.thermoresistible__bu EELTEHTLAYAEDIARNCAPASLAVIKQQLYGDAMDGVV--DVSARAEKL
Mb1099c|M.bovis_AF2122/97 DDLLTEARATATTISQMSASAARMAKEAVNR---AFESSLSEGLLYERRL
MLBr_02402|M.leprae_Br4923 DDLLPEAKAVATTISQMSRSATRMAKEAVNR---SFESTLAEGLLHERRL
Rv0222|M.tuberculosis_H37Rv GTALDAAIALAEKITANGPLAVVATKRIITE---SRGWSPDTMFAEQMKI
MUL_1114|M.ulcerans_Agy99 GAALDAAIALAEKITANGPLAVAATKRIITE---SRGWSLDTRFAQQMKI
: * :: .
Mflv_3132|M.gilvum_PYR-GCK HHRVMGGADAREGVAAFLERRTPRWSASVAQEWEPVPHVDREGSGRSDS
Mvan_3400|M.vanbaalenii_PYR-1 HHRVMGGADAREGVAAFLERRTPRWSSSVSKEWEPLREI----------
MMAR_2974|M.marinum_M HRRVMGSADAREGVEAFLQHRAPRWSASVSSAWKPLPAPDHREQP----
MAV_4717|M.avium_104 HERVMGGADAAEGVAAFREHRAPRFTARLSSEWEPLPEP----------
MAB_0104|M.abscessus_ATCC_1997 HLRLMGSQDAAEGPRAFIDGRPPRWAGQR--------------------
MSMEG_2229|M.smegmatis_MC2_155 MHESMVRPDLIEGITAFFEKRPPNFPPLAAE------------------
TH_4111|M.thermoresistible__bu MHESLRRPDVIEGITSFIEKRQPAFPPLAPSDP----------------
Mb1099c|M.bovis_AF2122/97 FHSAFATEDQSEGMAAFIEKRAPQFTHR---------------------
MLBr_02402|M.leprae_Br4923 FHSTFVTDDQSEGMAAFIEKRAPQFTHR---------------------
Rv0222|M.tuberculosis_H37Rv LVPVFTSNDAKEGAIAFAERRRPRWTGT---------------------
MUL_1114|M.ulcerans_Agy99 LFPIFTSNDAKEGAIAFAEKRPPRWTGT---------------------
: * ** :* : * * :.