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DDDPPGALVLDSVSHAFGDRTVLRDVSLTLTERRIAVVGANGSGKSTLARLFNGLVLPDTGSVRVHGIDT RRSVRKVRHLVGFVFTDPDRQILMPTVAEDVELSLSRLGLDRDARAVRTAEVLERFGLAGHADQPAHRLS GGQKQLLALATVLVTEPSVVVADEPTTLLDLRNARMLRAAFATLPTQLVLVTHDLDLAEDAERVIVLDEG RVVADDVPSVALPAYRRLMS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3463 | - | - | 100% (231) | ABC transporter related |
| M. gilvum PYR-GCK | Mflv_4055 | - | 8e-31 | 38.43% (216) | cobalt ABC transporter, ATPase subunit |
| M. gilvum PYR-GCK | Mflv_4127 | - | 4e-26 | 35.24% (227) | ABC transporter related |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3129c | ftsE | 2e-22 | 33.18% (220) | putative cell division ATP-binding protein FTSE (septation |
| M. tuberculosis H37Rv | Rv3102c | ftsE | 2e-22 | 33.18% (220) | putative cell division ATP-binding protein FTSE (septation |
| M. leprae Br4923 | MLBr_00669 | ftsE | 2e-22 | 32.73% (220) | putative cell division ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_2803c | - | 7e-26 | 37.93% (203) | methionine import ATP-binding protein metN |
| M. marinum M | MMAR_1530 | ftsE | 2e-23 | 33.64% (220) | cell division ATP-binding protein FtsE |
| M. avium 104 | MAV_4003 | ftsE | 5e-24 | 34.09% (220) | cell division ATP-binding protein FtsE |
| M. smegmatis MC2 155 | MSMEG_2610 | - | 2e-36 | 40.85% (213) | cobalt transport protein ATP-binding subunit |
| M. thermoresistible (build 8) | TH_4170 | - | 1e-88 | 71.74% (230) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_2409 | ftsE | 2e-23 | 33.64% (220) | cell division ATP-binding protein FtsE |
| M. vanbaalenii PYR-1 | Mvan_3227 | - | 1e-105 | 80.52% (231) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3129c|M.bovis_AF2122/97 -------MITLDHVTKQYKSSAR--PALDDINVKIDKGEFVFLIGPSGSG
Rv3102c|M.tuberculosis_H37Rv -------MITLDHVTKQYKSSAR--PALDDINVKIDKGEFVFLIGPSGSG
MMAR_1530|M.marinum_M -------MITLDHVSKQYKSSAR--PALDDINVKIDKGEFVFLIGPSGSG
MUL_2409|M.ulcerans_Agy99 -------MITLDHVSKQYKSSAR--PALDDINVKIDKGEFVFLIGPSGSG
MAV_4003|M.avium_104 ------MMITLDHVTKKYKASAR--PALEDVNVKIDKGEFVFLIGPSGSG
MLBr_00669|M.leprae_Br4923 -------MITLDHVSKKYKSLAR--PALDNVNVKIDKGEFVFLIGPSGSG
MAB_2803c|M.abscessus_ATCC_199 -MGDVAPLIQFQNVTKTFRVGKKTVTAVDDVSLDIGSGDVFAMIGYSGAG
Mflv_3463|M.gilvum_PYR-GCK MDDDPPGALVLDSVSHAFGDRTV----LRDVSLTLTER-RIAVVGANGSG
Mvan_3227|M.vanbaalenii_PYR-1 MTDDPPAAIVIDGVSHSYGERPV----LREISLTITER-RVGIVGANGSG
TH_4170|M.thermoresistible__bu MVDQQPDSVVFEDVSHSYGDRKV----LCDVSLVLTER-RIGIVGANGSG
MSMEG_2610|M.smegmatis_MC2_155 MTDT---AISIAALCHVYPDGHIG---LDGVDLEVAEGERVAVLGPNGAG
: : : : : : :.: : . . ::* .*:*
Mb3129c|M.bovis_AF2122/97 KSTFMRLLLAAETPTSGDVRVSKFHVNKLRGRHVPKLRQVIGCVFQDFR-
Rv3102c|M.tuberculosis_H37Rv KSTFMRLLLAAETPTSGDVRVSKFHVNKLRGRHVPKLRQVIGCVFQDFR-
MMAR_1530|M.marinum_M KSTFMRLLLAAETPTSGDVRVSKFHVNKLRGRNVPKLRQVIGCVFQDFR-
MUL_2409|M.ulcerans_Agy99 KSTFMRLLLAAETPTSGDVRVSKFHVNKLRGRNVPKLRQVIGCVFQDFR-
MAV_4003|M.avium_104 KSTFMRLLLGEENPTTGDIRVSKFHVNKLRGRHIPKLRQVIGTVFQDFR-
MLBr_00669|M.leprae_Br4923 KSTFMRLLLGAETPTSGDVRVSKFHVNKLPGRHIPRLRQVIGCVFQDFR-
MAB_2803c|M.abscessus_ATCC_199 KSTLVRLINGLERPTSGRVIVDGAEVSALGERELRGLRSDIGMIFQQFN-
Mflv_3463|M.gilvum_PYR-GCK KSTLARLFNGLVLPDTGSVRVHGIDTRR----SVRKVRHLVGFVFTDPDR
Mvan_3227|M.vanbaalenii_PYR-1 KSTLARLFNGLVLPDSGAVRVHGLDTRR----SAKQVRRLVGFVFTDPDR
TH_4170|M.thermoresistible__bu KSTFARMINGLVLPDRGTVRVCGLDTRR----HTRRVRRLAGFVFTDPDR
MSMEG_2610|M.smegmatis_MC2_155 KTTLMLHLNGVLTATSGTVRICGVPVARN---TLRDIRRRVGLVFQDPDD
*:*: : . . * : : . :* * :* :
Mb3129c|M.bovis_AF2122/97 LLQQKTVYDNVAFALEVIGKRTDAINRVVPEVLETVGLSGKANRLPDELS
Rv3102c|M.tuberculosis_H37Rv LLQQKTVYDNVAFALEVIGKRTDAINRVVPEVLETVGLSGKANRLPDELS
MMAR_1530|M.marinum_M LLQQKTVYENVAFALEVIGKRADAINRVVPDVLETVGLSGKANRLPHELS
MUL_2409|M.ulcerans_Agy99 LLQQKTVYENVAFALEVIGKRADAINRVVPDVLETVGLSGKANRLPHELS
MAV_4003|M.avium_104 LLQQKTVYENVAFALEVIGKRTDAINRVVPEVLETVGLSGKANRLPHELS
MLBr_00669|M.leprae_Br4923 LLQQKTVYENVAFALEVIGRRSDAINQVVPDVLETVGLSGKANRLPDELS
MAB_2803c|M.abscessus_ATCC_199 LFRSRTVAGNIAYPLRVAGWTADKRNARVAELLEFVGLGDKAKSYPDQLS
Mflv_3463|M.gilvum_PYR-GCK QILMPTVAEDVELSLSRLGLDRDARAVRTAEVLERFGLAGHADQPAHRLS
Mvan_3227|M.vanbaalenii_PYR-1 QILMPTVAEDIELSLSRRSLDRQTRTAKVAQVLERFGLAGHADQPAHLLS
TH_4170|M.thermoresistible__bu QILMPTVAEDIELSLSRHRLTTDERRDRVHEVLGRFGLAGHADHPAHLLS
MSMEG_2610|M.smegmatis_MC2_155 QLFMPTVAQDVAFGPANFGLAGEELAARVRHALELVSLTEHADRSPAHLS
: ** :: : . . * ..* :*. . **
Mb3129c|M.bovis_AF2122/97 GGEQQRVAIARAFVNRPLVLLADEPTGNLDPETSRDIMDLLERIN-RTGT
Rv3102c|M.tuberculosis_H37Rv GGEQQRVAIARAFVNRPLVLLADEPTGNLDPETSRDIMDLLERIN-RTGT
MMAR_1530|M.marinum_M GGEQQRVAIARAFVNRPLVLLADEPTGNLDPDTSKDIMDLLERIN-RTGT
MUL_2409|M.ulcerans_Agy99 GGEQQRVAIARAFVNRPLVLLADEPTGNLDPDTSKDIMDLLERIN-RTGT
MAV_4003|M.avium_104 GGEQQRVAIARAFVNRPLVLLADEPTGNLDPDTSKDIMDLLERIN-RTGT
MLBr_00669|M.leprae_Br4923 GGEQQRVAIARAFVNRPLVLLADEPTGNLDPDTSKDIMDLLERIN-RTGT
MAB_2803c|M.abscessus_ATCC_199 GGQKQRVGIARALATSPSVLLADEATSALDPETTSDVLRLLREVNAEFGV
Mflv_3463|M.gilvum_PYR-GCK GGQKQLLALATVLVTEPSVVVADEPTTLLDLRNARMLRAAFATLP----T
Mvan_3227|M.vanbaalenii_PYR-1 GGQKQLLALATVLVTEPAVVVADEPTTLLDLRNARMLRQAFAALH----T
TH_4170|M.thermoresistible__bu GGQKQLLALASVLVTEPRIVVADEPTTLLDLRNTRMIRDAFAALD----H
MSMEG_2610|M.smegmatis_MC2_155 GGQRRRAALATVLACDAEILVLDEPSANLDPVARRELAETLAALD----V
**::: .:* .:. . ::: **.: ** : : :
Mb3129c|M.bovis_AF2122/97 TVLMATHDHHIVDSMRQRVVELSLGRLVRD--------------------
Rv3102c|M.tuberculosis_H37Rv TVLMATHDHHIVDSMRQRVVELSLGRLVRD--------------------
MMAR_1530|M.marinum_M TVLMATHDHHIVDSMRQRVVELSLGRLVRD--------------------
MUL_2409|M.ulcerans_Agy99 TVLMATHDHHIVDSMRQRVVELSLGRLVRD--------------------
MAV_4003|M.avium_104 TVLMATHDHHIVDSMRQRVVELSLGRLVRD--------------------
MLBr_00669|M.leprae_Br4923 TVLMATHDHHIVDSMRQRVVELSLGRLVRD--------------------
MAB_2803c|M.abscessus_ATCC_199 TIVVITHEMDVVRTVADHVAVLADGKVVETGTVFDVFSTPQSEAGKRFVG
Mflv_3463|M.gilvum_PYR-GCK QLVLVTHDLDLAED-AERVIVLDEGRVVAD--------------------
Mvan_3227|M.vanbaalenii_PYR-1 QLVIVTHDLDLVDD-ADRVIVLDDGRVVAD--------------------
TH_4170|M.thermoresistible__bu QLVVVSHDLTLLDD-FDRVIVFDEGRVVAD--------------------
MSMEG_2610|M.smegmatis_MC2_155 TMLIVTHDLPYAAQLCTRAVVIDDGRVVAD--------------------
::: :*: :. : *::*
Mb3129c|M.bovis_AF2122/97 -----------------EQRG-----------------------------
Rv3102c|M.tuberculosis_H37Rv -----------------EQRG-----------------------------
MMAR_1530|M.marinum_M -----------------EQRG-----------------------------
MUL_2409|M.ulcerans_Agy99 -----------------EQRG-----------------------------
MAV_4003|M.avium_104 -----------------EQRG-----------------------------
MLBr_00669|M.leprae_Br4923 -----------------EWCG-----------------------------
MAB_2803c|M.abscessus_ATCC_199 TVLRNTPSGEDIARIAQRHKGRIVAVEISEGVQIGPALARATELGVRFEV
Mflv_3463|M.gilvum_PYR-GCK ---------------DVP--------------------------------
Mvan_3227|M.vanbaalenii_PYR-1 ---------------DVP--------------------------------
TH_4170|M.thermoresistible__bu ---------------DAP--------------------------------
MSMEG_2610|M.smegmatis_MC2_155 ---------------GDIG-----------------------------EI
Mb3129c|M.bovis_AF2122/97 VYG-----MDR----------------------------------
Rv3102c|M.tuberculosis_H37Rv VYG-----MDR----------------------------------
MMAR_1530|M.marinum_M VYG-----MDR----------------------------------
MUL_2409|M.ulcerans_Agy99 VYG-----MDR----------------------------------
MAV_4003|M.avium_104 IYG-----MDR----------------------------------
MLBr_00669|M.leprae_Br4923 IYG-----MDR----------------------------------
MAB_2803c|M.abscessus_ATCC_199 VYGGITTLQSRSFGNLTLELEGPDDQVAHVVSDLSAVTTVQRVAR
Mflv_3463|M.gilvum_PYR-GCK --SVALPAYRRLMS-------------------------------
Mvan_3227|M.vanbaalenii_PYR-1 --SVALSTYRRLMT-------------------------------
TH_4170|M.thermoresistible__bu --AAAIDAYERMMLR------------------------------
MSMEG_2610|M.smegmatis_MC2_155 LGDAHLLAAHRLELPWGFAVPERSRN-------------------
*