For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
APSTYTLAMAQPRRIAGPDGSANVAHAVRLVEQAAGADLVCFPEFSPGPVRAHDTFYDAGPALAAAARAC DVNVVWSRTERCDDGRNRLVVYVTGRDGDPVLRYARTHPATIPPGEDGELVSPADTFGNFEVDGIPMGIV VCSEMWTPEIARIVALRGAEIILSPAGGGFTSLTRNWQIIVSARAIENLCYIGLTNNLWGDEQGAAMITG PEHPLAHAGRSELVTATVDLDRLRWLRAHDDSMAEPKAFDSIPGLLRARRPELYGELVAPQADAYDYANG QA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3160 | - | - | 100% (283) | Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0813 | - | 7e-10 | 29.59% (267) | Nitrilase/cyanide hydratase and apolipoprotein |
| M. vanbaalenii PYR-1 | Mvan_1224 | - | 1e-05 | 28.26% (230) | Nitrilase/cyanide hydratase and apolipoprotein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0490c | - | 3e-08 | 24.31% (255) | hypothetical protein Mb0490c |
| M. gilvum PYR-GCK | Mflv_0095 | - | 2e-07 | 28.19% (259) | Nitrilase/cyanide hydratase and apolipoprotein |
| M. tuberculosis H37Rv | Rv0480c | - | 3e-08 | 24.31% (255) | amidohydrolase |
| M. leprae Br4923 | MLBr_02449 | - | 4e-09 | 24.90% (261) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_2545c | - | 2e-11 | 29.24% (301) | nitrilase/cyanide hydratase and apolipoprotein |
| M. marinum M | MMAR_0805 | - | 4e-07 | 27.27% (198) | amidohydrolase |
| M. avium 104 | MAV_4670 | - | 2e-10 | 25.67% (261) | carbon-nitrogen hydrolase |
| M. smegmatis MC2 155 | MSMEG_6733 | - | 1e-14 | 30.88% (272) | hydrolase, carbon-nitrogen family protein |
| M. thermoresistible (build 8) | TH_0873 | - | 5e-10 | 26.88% (253) | POSSIBLE AMIDOHYDROLASE |
| M. ulcerans Agy99 | MUL_4548 | - | 2e-07 | 27.06% (255) | amidohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0805|M.marinum_M -------------------------------MRIALAQILSGTDPTANLE
MUL_4548|M.ulcerans_Agy99 -------------------------------MRIALAQILSGTDPTANLE
MLBr_02449|M.leprae_Br4923 -------------------------------MRIALAQILSGTDPVANLR
Mb0490c|M.bovis_AF2122/97 MRRARRRAQAGLPGSCARRCGALVAGPRLARMRIALAQIRSGTDPAANLQ
Rv0480c|M.tuberculosis_H37Rv -------------------------------MRIALAQIRSGTDPAANLQ
MAV_4670|M.avium_104 -------------------------------MRIALAQILSGTDPAANLA
Mflv_0095|M.gilvum_PYR-GCK ---------------------------MRSGMRIALAQIQSSTDPAANLT
TH_0873|M.thermoresistible__bu -------------------------------MRIALAQIRSGTDPSANLN
MSMEG_6733|M.smegmatis_MC2_155 ----------------------------MRTVDVAVVQEPAVAG-DVAAN
Mvan_3160|M.vanbaalenii_PYR-1 --------------------------MAPSTYTLAMAQPRRIAGPDGSAN
MAB_2545c|M.abscessus_ATCC_199 ---MPTSGFVVATAFTPMSSPARVSAPLRTPVRVGLVQHRWLADPDQLRD
:.:.* :.
MMAR_0805|M.marinum_M LVRDYAERAADAGARLVVFPEATMC-------RFGVPLGPVAQPLDGPWA
MUL_4548|M.ulcerans_Agy99 LVRDYAERAADAGARLVVFPEATMC-------RFGVPLGPVAQPLDGPWA
MLBr_02449|M.leprae_Br4923 LVREYTGQATDAGATLVVFPEATMC-------RFGVPLGPVAEPIDGPWA
Mb0490c|M.bovis_AF2122/97 LVGKYAGEAATAGAQLVVFPEATMC-------RLGVPLRQVAEPVDGPWA
Rv0480c|M.tuberculosis_H37Rv LVGKYAGEAATAGAQLVVFPEATMC-------RLGVPLRQVAEPVDGPWA
MAV_4670|M.avium_104 LVGEYTRRAAGAGARLVVFPEATMC-------RFGVPLAPIAEPVDGPWA
Mflv_0095|M.gilvum_PYR-GCK LVEEYTRRAVDAGASLVLFPEATMV-------RFGVPLGGVAEPFDGPWA
TH_0873|M.thermoresistible__bu LVEEYTRRAAATGAGLVLFPEATMC-------RFGVSLKPVAEPLDGPWA
MSMEG_6733|M.smegmatis_MC2_155 VRRAVAALAKHPGADLVVFPELFLCGY-----RLDVVADAAIEMIPEPGP
Mvan_3160|M.vanbaalenii_PYR-1 VAHAVRLVEQAAGADLVCFPEFSPG-----------PVRAHDTFYDAG--
MAB_2545c|M.abscessus_ATCC_199 QLLEGVRLAVAQGARAVFLPELTLSRYPADVRAGTNPGDRAEDLLTGPTF
** * :**
MMAR_0805|M.marinum_M NGVRRIAAQTGITVVAGMFTPADAGRVSNTLFAAGPGAPNQPDDHYHKIH
MUL_4548|M.ulcerans_Agy99 NGVRRIAAQTGITVVAGMFTPADAGRVSNTLFAAGPGAPNQPDDHYHKIH
MLBr_02449|M.leprae_Br4923 NGVRQIATEAGITIIAGIFTPADDGRVMNTLIAAGPGTPNQPDTHYHKIH
Mb0490c|M.bovis_AF2122/97 NGVRRIATEAGITVIAGMFTPTGDGRVTNTLIAAGPGTPNQPDAHYHKIH
Rv0480c|M.tuberculosis_H37Rv NGVRRIATEAGITVIAGMFTPTGDGRVTNTLIAAGPGTPNQPDAHYHKIH
MAV_4670|M.avium_104 DGVRRIATEANVTVIAGMFTPSGDGRVKNTLLVAN--SDDQAVTHYDKIH
Mflv_0095|M.gilvum_PYR-GCK NAVRDIAARAGIVVVAGMFVPSDDGRSFNTLLATGPGVEAR----YDKIH
TH_0873|M.thermoresistible__bu TAVREIAAGAGVVVVAGMFTPSGDGRVTNTLLATGPGVAAH----YHKIH
MSMEG_6733|M.smegmatis_MC2_155 VADLCAAAAAHDTAVVTGFAERSGDLVYNSLLCIDRTGAVAG--VYRKTH
Mvan_3160|M.vanbaalenii_PYR-1 PALAAAARACDVNVVWSRTERCDDGR--NRLVVYVTGRDGDPVLRYARTH
MAB_2545c|M.abscessus_ATCC_199 CFAAHAATENGVLVHASLYERADAADGLGYNTAILVSPSGELVGRTRKLH
* . . : *
MMAR_0805|M.marinum_M LYDAFGFAESRTVAPGHEP------VVITVDD----VQVGLTVCYDIRFP
MUL_4548|M.ulcerans_Agy99 LYDAFGFAESRTVAPGHEP------VVITVDD----FQVGLTVCYDIRFP
MLBr_02449|M.leprae_Br4923 LYDAFGFTESRTVTAGHEP------VVITVDD----VQVGLTICYDIRFP
Mb0490c|M.bovis_AF2122/97 LYDAFGFTESRTVAPGREP------VVVVVDG----VRVGLTVCYDIRFP
Rv0480c|M.tuberculosis_H37Rv LYDAFGFTESRTVAPGREP------VVVVVDG----VRVGLTVCYDIRFP
MAV_4670|M.avium_104 LYDAFGFTESRTVAPGREP------VVVGVDG----VRVGLSVCYDIRFP
Mflv_0095|M.gilvum_PYR-GCK LYDAFGFLESKTVAPGREP------VVISVDTESGPVTVGLTLCYDIRFP
TH_0873|M.thermoresistible__bu LYDAYGFTESRTVAPGSEP------VTIDVGG----VRVGLTTCYDIRFP
MSMEG_6733|M.smegmatis_MC2_155 LFG----AECEAFATGDRL------EVIEVDG----LRVGPMICFDVEFP
Mvan_3160|M.vanbaalenii_PYR-1 PATIPPGEDGELVSPADTF------GNFEVDG----IPMGIVVCSEMWTP
MAB_2545c|M.abscessus_ATCC_199 IPVTAGYYEDTYFRPGPAENAYPVYRPAELDG----AAVGMPTCWDEWFP
: . .. :. :* * : *
MMAR_0805|M.marinum_M ALYTELARRGAELIVVSASWGSGPGKLDQWTLLARARALDSASYVAAAGQ
MUL_4548|M.ulcerans_Agy99 ALYTELARRGAELIVVSASWGSGPGKLDQWTLLARARALDSASYVAAAGQ
MLBr_02449|M.leprae_Br4923 ALYTELARRGAQLIVVCASWGSGAGKLEQWTLLARARALDSMSYVAAVGQ
Mb0490c|M.bovis_AF2122/97 ALYTELARRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAAGQ
Rv0480c|M.tuberculosis_H37Rv ALYTELARRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAAGQ
MAV_4670|M.avium_104 ELYTELARRGAQLIAVCASWGAGPGKLDQWTLLARARALDSMSYIAAAGQ
Mflv_0095|M.gilvum_PYR-GCK ELYVELADRGAEIITAHASWGTGPGKLEQWTLLARARAIDTSSVVAAVGQ
TH_0873|M.thermoresistible__bu ELYVELARRGAELLTVHASWGSGPGKLEQWTLLARARALDTTCVVAAVGQ
MSMEG_6733|M.smegmatis_MC2_155 EIARTLALSGVDLFVVSSANMFPYHHDHRVACLSRALENRTPLVYSNLIG
Mvan_3160|M.vanbaalenii_PYR-1 EIARIVALRGAEIILSPAGGGFTS-LTRNWQIIVSARAIENLCYIGLTNN
MAB_2545c|M.abscessus_ATCC_199 EVSRMYSLAGAEILVYPTAIGSEPAFPSFDTQPLWQHVIVGNGITAGTFM
: : *.::: :. .
MMAR_0805|M.marinum_M ADPGDTASDPGGGSGAPRGVGGSLVASPLGEVVASAG-SDPQLVVADIDL
MUL_4548|M.ulcerans_Agy99 ADPGDTASDPGGGSGAPRGVGGSLVTSPLGEVVASAG-SDPQLVVADIDL
MLBr_02449|M.leprae_Br4923 ADPGGALTDSGPSSAAPTGVGGSLVASPLGEVVASAG-TESKLVVADIDV
Mb0490c|M.bovis_AF2122/97 ADPGDARTGVGASSAAPTGVGGSLVASPLGEVVVSAG-TQPQLLVADIDV
Rv0480c|M.tuberculosis_H37Rv ADPGDARTGVGASSAAPTGVGGSLVASPLGEVVVSAG-TQPQLLVADIDV
MAV_4670|M.avium_104 ADPGGSLS----ASGAPTGVGGSLVASPLGEVVASAG-AQPQLVLADIDV
Mflv_0095|M.gilvum_PYR-GCK AYPGDEIAALG-----PTGVGGSLVASALGEVLASAG-DDPELLVCDVDL
TH_0873|M.thermoresistible__bu AYPGDEIAAQG-----PTGVGGSLVASATGEVLAAAG-PEPELLVADLDL
MSMEG_6733|M.smegmatis_MC2_155 AEAG------------LTFVGGSRVVDAGGELLVECG-GEVSVARCRVTP
Mvan_3160|M.vanbaalenii_PYR-1 LWGDEQGAAMITGPEHPLAHAGR---SELVTATVDLD-RLRWLRAHDDSM
MAB_2545c|M.abscessus_ATCC_199 VVPNRFGDE-----GTVNFYGSSFISDPYGRILAQAPRDAPAVLVADLDL
. .. . . :
MMAR_0805|M.marinum_M AKVGAARDNIGVLRNQSRFTQTDKAQSRR----------
MUL_4548|M.ulcerans_Agy99 AKVGAARDNIGMLRNQSRFTQTDKAQSRR----------
MLBr_02449|M.leprae_Br4923 DNVTTARENIAVLRNRSHFA-------------------
Mb0490c|M.bovis_AF2122/97 DNVAAARDRIAVLRNQTDFVQIDKAQSRG----------
Rv0480c|M.tuberculosis_H37Rv DNVAAARDRIAVLRNQTDFVQIDKAQSRG----------
MAV_4670|M.avium_104 DRVAQARKTIAALSNRSDFAQVGRAESVG----------
Mflv_0095|M.gilvum_PYR-GCK EAARKARQTVAVMQNRSGFAHRGKAESRG----------
TH_0873|M.thermoresistible__bu DAARRARDTIAVLRNRSDVAQWGKAESVG----------
MSMEG_6733|M.smegmatis_MC2_155 ATATSTEDDVDYLRHRRPELYRLK---------------
Mvan_3160|M.vanbaalenii_PYR-1 AEPKAFDSIPGLLRARRPELYGELVAPQADAYDYANGQA
MAB_2545c|M.abscessus_ATCC_199 EQRKDWLDLFPFNTTRRPDTYARLAAPVDTSHPHGSEAS
. :