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M. abscessus ATCC 19977 MAB_2545c (-)

annotation: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
coordinates: 2592303 - 2593286
length: 327

PTSGFVVATAFTPMSSPARVSAPLRTPVRVGLVQHRWLADPDQLRDQLLEGVRLAVAQGARAVFLPELTL
SRYPADVRAGTNPGDRAEDLLTGPTFCFAAHAATENGVLVHASLYERADAADGLGYNTAILVSPSGELVG
RTRKLHIPVTAGYYEDTYFRPGPAENAYPVYRPAELDGAAVGMPTCWDEWFPEVSRMYSLAGAEILVYPT
AIGSEPAFPSFDTQPLWQHVIVGNGITAGTFMVVPNRFGDEGTVNFYGSSFISDPYGRILAQAPRDAPAV
LVADLDLEQRKDWLDLFPFNTTRRPDTYARLAAPVDTSHPHGSEAS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2545c--100% (327)nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
M. abscessus ATCC 19977MAB_2818c-6e-2731.08% (296) putative hydrolase
M. abscessus ATCC 19977MAB_0819-3e-1429.22% (243) carbon-nitrogen hydrolase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0490c-4e-1124.73% (283) hypothetical protein Mb0490c
M. gilvum PYR-GCKMflv_0095-1e-1427.99% (268) Nitrilase/cyanide hydratase and apolipoprotein
M. tuberculosis H37RvRv0480c-3e-1024.54% (273) amidohydrolase
M. leprae Br4923MLBr_02449-1e-0723.08% (273) putative hydrolase
M. marinum MMMAR_0805-5e-1224.26% (272) amidohydrolase
M. avium 104MAV_4670-1e-1223.88% (268) carbon-nitrogen hydrolase
M. smegmatis MC2 155MSMEG_0443-1e-12768.32% (322) hydrolase, carbon-nitrogen family protein
M. thermoresistible (build 8)TH_0873-6e-1528.41% (264) POSSIBLE AMIDOHYDROLASE
M. ulcerans Agy99MUL_4548-6e-1224.26% (272) amidohydrolase
M. vanbaalenii PYR-1Mvan_0813-2e-1328.41% (264) Nitrilase/cyanide hydratase and apolipoprotein

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0805|M.marinum_M               -------------------------------MRIALAQILSGTDPTANLE
MUL_4548|M.ulcerans_Agy99           -------------------------------MRIALAQILSGTDPTANLE
MLBr_02449|M.leprae_Br4923          -------------------------------MRIALAQILSGTDPVANLR
Mb0490c|M.bovis_AF2122/97           MRRARRRAQAGLPGSCARRCGALVAGPRLARMRIALAQIRSGTDPAANLQ
Rv0480c|M.tuberculosis_H37Rv        -------------------------------MRIALAQIRSGTDPAANLQ
MAV_4670|M.avium_104                -------------------------------MRIALAQILSGTDPAANLA
Mflv_0095|M.gilvum_PYR-GCK          ---------------------------MRSGMRIALAQIQSSTDPAANLT
Mvan_0813|M.vanbaalenii_PYR-1       -------------------------------MRIALAQIRGSTDPAENLD
TH_0873|M.thermoresistible__bu      -------------------------------MRIALAQIRSGTDPSANLN
MAB_2545c|M.abscessus_ATCC_199      ---MPTSGFVVATAFTPMSSPARVSAPLRTPVRVGLVQHRWLADPDQLRD
MSMEG_0443|M.smegmatis_MC2_155      --------MITLTATAPES-LSRSTASQRPPLRVGLVQHRWRPDAGELVK
                                                                   :*:.*.*    .*.     

MMAR_0805|M.marinum_M               LVRDYAERAADAGARLVVFPEATMCRFGVPLGPVAQP-------LDGPWA
MUL_4548|M.ulcerans_Agy99           LVRDYAERAADAGARLVVFPEATMCRFGVPLGPVAQP-------LDGPWA
MLBr_02449|M.leprae_Br4923          LVREYTGQATDAGATLVVFPEATMCRFGVPLGPVAEP-------IDGPWA
Mb0490c|M.bovis_AF2122/97           LVGKYAGEAATAGAQLVVFPEATMCRLGVPLRQVAEP-------VDGPWA
Rv0480c|M.tuberculosis_H37Rv        LVGKYAGEAATAGAQLVVFPEATMCRLGVPLRQVAEP-------VDGPWA
MAV_4670|M.avium_104                LVGEYTRRAAGAGARLVVFPEATMCRFGVPLAPIAEP-------VDGPWA
Mflv_0095|M.gilvum_PYR-GCK          LVEEYTRRAVDAGASLVLFPEATMVRFGVPLGGVAEP-------FDGPWA
Mvan_0813|M.vanbaalenii_PYR-1       LVEEYTGRAAEAGASLVLFPEATICRFGVPPAEIAEP-------FDGPWA
TH_0873|M.thermoresistible__bu      LVEEYTRRAAATGAGLVLFPEATMCRFGVSLKPVAEP-------LDGPWA
MAB_2545c|M.abscessus_ATCC_199      QLLEGVRLAVAQGARAVFLPELTLSRYPADVRAGTNPGDRAEDLLTGPTF
MSMEG_0443|M.smegmatis_MC2_155      VLREGIDRAAGEGAKAVFLPEITLLRYPADTPAGPNPGDVAEDLTGGPTF
                                     : .    *.  **  *.:** *: *  .     .:*         **  

MMAR_0805|M.marinum_M               NGVRRIAAQTGITVVAGMFTPADAG--RVSNTLFAAGPGAPNQPDDHYHK
MUL_4548|M.ulcerans_Agy99           NGVRRIAAQTGITVVAGMFTPADAG--RVSNTLFAAGPGAPNQPDDHYHK
MLBr_02449|M.leprae_Br4923          NGVRQIATEAGITIIAGIFTPADDG--RVMNTLIAAGPGTPNQPDTHYHK
Mb0490c|M.bovis_AF2122/97           NGVRRIATEAGITVIAGMFTPTGDG--RVTNTLIAAGPGTPNQPDAHYHK
Rv0480c|M.tuberculosis_H37Rv        NGVRRIATEAGITVIAGMFTPTGDG--RVTNTLIAAGPGTPNQPDAHYHK
MAV_4670|M.avium_104                DGVRRIATEANVTVIAGMFTPSGDG--RVKNTLLVAN--SDDQAVTHYDK
Mflv_0095|M.gilvum_PYR-GCK          NAVRDIAARAGIVVVAGMFVPSDDG--RSFNTLLATGPGVEAR----YDK
Mvan_0813|M.vanbaalenii_PYR-1       SAVRGIAARAGVVVVAGMYVPSDDDD-RVTNTLIATGPGVDAR----YDK
TH_0873|M.thermoresistible__bu      TAVREIAAGAGVVVVAGMFTPSGDG--RVTNTLLATGPGVAAH----YHK
MAB_2545c|M.abscessus_ATCC_199      CFAAHAATENGVLVHASLYERADAADGLGYNTAILVSPSGELVG--RTRK
MSMEG_0443|M.smegmatis_MC2_155      ELAAEAARANGIFVHASLYEKAPAADGLGYNTAILVSPEGELVG--RTRK
                                      .   *   .: : *.::  :        ** : ..            *

MMAR_0805|M.marinum_M               IHLYDAFGFAESRTVAPG------HEPVVITVDD----VQVGLTVCYDIR
MUL_4548|M.ulcerans_Agy99           IHLYDAFGFAESRTVAPG------HEPVVITVDD----FQVGLTVCYDIR
MLBr_02449|M.leprae_Br4923          IHLYDAFGFTESRTVTAG------HEPVVITVDD----VQVGLTICYDIR
Mb0490c|M.bovis_AF2122/97           IHLYDAFGFTESRTVAPG------REPVVVVVDG----VRVGLTVCYDIR
Rv0480c|M.tuberculosis_H37Rv        IHLYDAFGFTESRTVAPG------REPVVVVVDG----VRVGLTVCYDIR
MAV_4670|M.avium_104                IHLYDAFGFTESRTVAPG------REPVVVGVDG----VRVGLSVCYDIR
Mflv_0095|M.gilvum_PYR-GCK          IHLYDAFGFLESKTVAPG------REPVVISVDTESGPVTVGLTLCYDIR
Mvan_0813|M.vanbaalenii_PYR-1       IHLYDAFGFSESKTVAPG------RDPVVITVESESGPVKVGLTLCYDIR
TH_0873|M.thermoresistible__bu      IHLYDAYGFTESRTVAPG------SEPVTIDV----GGVRVGLTTCYDIR
MAB_2545c|M.abscessus_ATCC_199      LHIPVTAGYYEDTYFRPGPAEN----AYPVYRPAELDGAAVGMPTCWDEW
MSMEG_0443|M.smegmatis_MC2_155      MHIPISAGYYEDTYFRPGPARPSDGDPYPVYSPEGLG-ARIGLPTCWDEW
                                    :*:  : *: *.  . .*        .  :          :*:. *:*  

MMAR_0805|M.marinum_M               FPALYTELARRGAELIVVSASWGSGPGKLDQWTLLARARALDSASYVAAA
MUL_4548|M.ulcerans_Agy99           FPALYTELARRGAELIVVSASWGSGPGKLDQWTLLARARALDSASYVAAA
MLBr_02449|M.leprae_Br4923          FPALYTELARRGAQLIVVCASWGSGAGKLEQWTLLARARALDSMSYVAAV
Mb0490c|M.bovis_AF2122/97           FPALYTELARRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAA
Rv0480c|M.tuberculosis_H37Rv        FPALYTELARRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAA
MAV_4670|M.avium_104                FPELYTELARRGAQLIAVCASWGAGPGKLDQWTLLARARALDSMSYIAAA
Mflv_0095|M.gilvum_PYR-GCK          FPELYVELADRGAEIITAHASWGTGPGKLEQWTLLARARAIDTSSVVAAV
Mvan_0813|M.vanbaalenii_PYR-1       FPELYVELAERGAEIITAHASWGNGPGKIDQWTLLARARAIDTSTVVAAV
TH_0873|M.thermoresistible__bu      FPELYVELARRGAELLTVHASWGSGPGKLEQWTLLARARALDTTCVVAAV
MAB_2545c|M.abscessus_ATCC_199      FPEVSRMYSLAGAEILVYPTAIGSEPAFPSFDTQPLWQHVIVGNGITAGT
MSMEG_0443|M.smegmatis_MC2_155      FPEVARCYSLGGAEIVVYPTAIGSEPVFPAFDTQPLWQQVIVANGISSGL
                                    ** :    :  **:::.  :: *  .      *     :.:      :. 

MMAR_0805|M.marinum_M               GQADPGDTASDPGGGSGAPRGVGGSLVASPLGEVVASAGSD-PQLVVADI
MUL_4548|M.ulcerans_Agy99           GQADPGDTASDPGGGSGAPRGVGGSLVTSPLGEVVASAGSD-PQLVVADI
MLBr_02449|M.leprae_Br4923          GQADPGGALTDSGPSSAAPTGVGGSLVASPLGEVVASAGTE-SKLVVADI
Mb0490c|M.bovis_AF2122/97           GQADPGDARTGVGASSAAPTGVGGSLVASPLGEVVVSAGTQ-PQLLVADI
Rv0480c|M.tuberculosis_H37Rv        GQADPGDARTGVGASSAAPTGVGGSLVASPLGEVVVSAGTQ-PQLLVADI
MAV_4670|M.avium_104                GQADPGGSLS----ASGAPTGVGGSLVASPLGEVVASAGAQ-PQLVLADI
Mflv_0095|M.gilvum_PYR-GCK          GQAYPGDEIAALG-----PTGVGGSLVASALGEVLASAGDD-PELLVCDV
Mvan_0813|M.vanbaalenii_PYR-1       GQAYPGDEIAALG-----PTGVGHSVVASALGEVLASAGAD-PQLLMCDI
TH_0873|M.thermoresistible__bu      GQAYPGDEIAAQG-----PTGVGGSLVASATGEVLAAAGPE-PELLVADL
MAB_2545c|M.abscessus_ATCC_199      FMVVPNRFGDEGT-----VNFYGSSFISDPYGRILAQAPRDAPAVLVADL
MSMEG_0443|M.smegmatis_MC2_155      FMVVPNRTGDEGS-----LSFYGSSFISDPFGRVLVSAPRDEEAVLVADL
                                      . *.                * *.::.. *.::. *  :   :::.*:

MMAR_0805|M.marinum_M               DLAKVGAARDNIGVLRNQSRFTQTDKAQSRR-------------------
MUL_4548|M.ulcerans_Agy99           DLAKVGAARDNIGMLRNQSRFTQTDKAQSRR-------------------
MLBr_02449|M.leprae_Br4923          DVDNVTTARENIAVLRNRSHFA----------------------------
Mb0490c|M.bovis_AF2122/97           DVDNVAAARDRIAVLRNQTDFVQIDKAQSRG-------------------
Rv0480c|M.tuberculosis_H37Rv        DVDNVAAARDRIAVLRNQTDFVQIDKAQSRG-------------------
MAV_4670|M.avium_104                DVDRVAQARKTIAALSNRSDFAQVGRAESVG-------------------
Mflv_0095|M.gilvum_PYR-GCK          DLEAARKARQTVAVMQNRSGFAHRGKAESRG-------------------
Mvan_0813|M.vanbaalenii_PYR-1       DLEAARAARQTVAVMHNRSEAVRSSRERSSPAVRSSRERSSPAVRSSRER
TH_0873|M.thermoresistible__bu      DLDAARRARDTIAVLRNRSDVAQWGKAESVG-------------------
MAB_2545c|M.abscessus_ATCC_199      DLEQRKDWLDLFPFNTTRRPDTYARLAAPVDTSHPHGSEAS---------
MSMEG_0443|M.smegmatis_MC2_155      DLDQRRDWLELFPFLLTRRPESYGALTEPVDPDHPYGAGHAATAVVK---
                                    *:       . .    .: