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RIALAQIRSGTDPAANLQLVGKYAGEAATAGAQLVVFPEATMCRLGVPLRQVAEPVDGPWANGVRRIATE AGITVIAGMFTPTGDGRVTNTLIAAGPGTPNQPDAHYHKIHLYDAFGFTESRTVAPGREPVVVVVDGVRV GLTVCYDIRFPALYTELARRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAAGQADPGDARTG VGASSAAPTGVGGSLVASPLGEVVVSAGTQPQLLVADIDVDNVAAARDRIAVLRNQTDFVQIDKAQSRG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0480c | - | - | 100% (280) | POSSIBLE AMIDOHYDROLASE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0490c | - | 1e-159 | 100.00% (280) | hypothetical protein Mb0490c |
| M. gilvum PYR-GCK | Mflv_0095 | - | 1e-96 | 64.44% (284) | Nitrilase/cyanide hydratase and apolipoprotein |
| M. leprae Br4923 | MLBr_02449 | - | 1e-126 | 81.85% (270) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_4076 | - | 5e-90 | 61.94% (268) | putative nitrilase/cyanide hydratase |
| M. marinum M | MMAR_0805 | - | 1e-124 | 78.85% (279) | amidohydrolase |
| M. avium 104 | MAV_4670 | - | 1e-120 | 77.86% (280) | carbon-nitrogen hydrolase |
| M. smegmatis MC2 155 | MSMEG_0924 | - | 3e-98 | 66.04% (268) | hydrolase, carbon-nitrogen family protein |
| M. thermoresistible (build 8) | TH_0873 | - | 1e-106 | 69.64% (280) | POSSIBLE AMIDOHYDROLASE |
| M. ulcerans Agy99 | MUL_4548 | - | 1e-123 | 77.78% (279) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_0813 | - | 1e-93 | 61.13% (283) | Nitrilase/cyanide hydratase and apolipoprotein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0480c|M.tuberculosis_H37Rv -------------------------------MRIALAQIRSGTDPAANLQ
Mb0490c|M.bovis_AF2122/97 MRRARRRAQAGLPGSCARRCGALVAGPRLARMRIALAQIRSGTDPAANLQ
MLBr_02449|M.leprae_Br4923 -------------------------------MRIALAQILSGTDPVANLR
MMAR_0805|M.marinum_M -------------------------------MRIALAQILSGTDPTANLE
MUL_4548|M.ulcerans_Agy99 -------------------------------MRIALAQILSGTDPTANLE
MAV_4670|M.avium_104 -------------------------------MRIALAQILSGTDPAANLA
MAB_4076|M.abscessus_ATCC_1997 -------------------------------MRIVLAQITSGADPTENLA
Mflv_0095|M.gilvum_PYR-GCK ---------------------------MRSGMRIALAQIQSSTDPAANLT
Mvan_0813|M.vanbaalenii_PYR-1 -------------------------------MRIALAQIRGSTDPAENLD
TH_0873|M.thermoresistible__bu -------------------------------MRIALAQIRSGTDPSANLN
MSMEG_0924|M.smegmatis_MC2_155 ------------------------------MMRIALAQITTGTDPSSNLE
***.**** .:** **
Rv0480c|M.tuberculosis_H37Rv LVGKYAGEAATAGAQLVVFPEATMCRLGVPLRQVAEPVDGPWANGVRRIA
Mb0490c|M.bovis_AF2122/97 LVGKYAGEAATAGAQLVVFPEATMCRLGVPLRQVAEPVDGPWANGVRRIA
MLBr_02449|M.leprae_Br4923 LVREYTGQATDAGATLVVFPEATMCRFGVPLGPVAEPIDGPWANGVRQIA
MMAR_0805|M.marinum_M LVRDYAERAADAGARLVVFPEATMCRFGVPLGPVAQPLDGPWANGVRRIA
MUL_4548|M.ulcerans_Agy99 LVRDYAERAADAGARLVVFPEATMCRFGVPLGPVAQPLDGPWANGVRRIA
MAV_4670|M.avium_104 LVGEYTRRAAGAGARLVVFPEATMCRFGVPLAPIAEPVDGPWADGVRRIA
MAB_4076|M.abscessus_ATCC_1997 TVAATVRDAAAQGATLIVFPEATMCRFGVPLGPVAQPVNGRWADGVRAIA
Mflv_0095|M.gilvum_PYR-GCK LVEEYTRRAVDAGASLVLFPEATMVRFGVPLGGVAEPFDGPWANAVRDIA
Mvan_0813|M.vanbaalenii_PYR-1 LVEEYTGRAAEAGASLVLFPEATICRFGVPPAEIAEPFDGPWASAVRGIA
TH_0873|M.thermoresistible__bu LVEEYTRRAAATGAGLVLFPEATMCRFGVSLKPVAEPLDGPWATAVREIA
MSMEG_0924|M.smegmatis_MC2_155 LVESCTRRAADDGARLVLFPEATMCRFGVPLGPVAQPLDGPWARAVRDIA
* . *. ** *::*****: *:**. :*:*.:* ** .** **
Rv0480c|M.tuberculosis_H37Rv TEAGITVIAGMFTPTGDG-RVTNTLIAAGPGTPNQPDAHYHKIHLYDAFG
Mb0490c|M.bovis_AF2122/97 TEAGITVIAGMFTPTGDG-RVTNTLIAAGPGTPNQPDAHYHKIHLYDAFG
MLBr_02449|M.leprae_Br4923 TEAGITIIAGIFTPADDG-RVMNTLIAAGPGTPNQPDTHYHKIHLYDAFG
MMAR_0805|M.marinum_M AQTGITVVAGMFTPADAG-RVSNTLFAAGPGAPNQPDDHYHKIHLYDAFG
MUL_4548|M.ulcerans_Agy99 AQTGITVVAGMFTPADAG-RVSNTLFAAGPGAPNQPDDHYHKIHLYDAFG
MAV_4670|M.avium_104 TEANVTVIAGMFTPSGDG-RVKNTLLVAN--SDDQAVTHYDKIHLYDAFG
MAB_4076|M.abscessus_ATCC_1997 DEAGLTVVVGMFTPAGDG-RVHNTLLATGP----GVDTHYNKIHLYDAFG
Mflv_0095|M.gilvum_PYR-GCK ARAGIVVVAGMFVPSDDG-RSFNTLLATGP----GVEARYDKIHLYDAFG
Mvan_0813|M.vanbaalenii_PYR-1 ARAGVVVVAGMYVPSDDDDRVTNTLIATGP----GVDARYDKIHLYDAFG
TH_0873|M.thermoresistible__bu AGAGVVVVAGMFTPSGDG-RVTNTLLATGP----GVAAHYHKIHLYDAYG
MSMEG_0924|M.smegmatis_MC2_155 ARAGVVVVAGMFSPSDDG-RVTNTLIAAGA----GVDTHYHKIHLYDAFG
:.:.::.*:: *:. . * ***:.:. :*.*******:*
Rv0480c|M.tuberculosis_H37Rv FTESRTVAPGREPVVVVVD----GVRVGLTVCYDIRFPALYTELARRGAQ
Mb0490c|M.bovis_AF2122/97 FTESRTVAPGREPVVVVVD----GVRVGLTVCYDIRFPALYTELARRGAQ
MLBr_02449|M.leprae_Br4923 FTESRTVTAGHEPVVITVD----DVQVGLTICYDIRFPALYTELARRGAQ
MMAR_0805|M.marinum_M FAESRTVAPGHEPVVITVD----DVQVGLTVCYDIRFPALYTELARRGAE
MUL_4548|M.ulcerans_Agy99 FAESRTVAPGHEPVVITVD----DFQVGLTVCYDIRFPALYTELARRGAE
MAV_4670|M.avium_104 FTESRTVAPGREPVVVGVD----GVRVGLSVCYDIRFPELYTELARRGAQ
MAB_4076|M.abscessus_ATCC_1997 FRESATVAPGHEPVLITVD----GVAVGLTTCYDIRFPGLYTDLARRGAQ
Mflv_0095|M.gilvum_PYR-GCK FLESKTVAPGREPVVISVDTESGPVTVGLTLCYDIRFPELYVELADRGAE
Mvan_0813|M.vanbaalenii_PYR-1 FSESKTVAPGRDPVVITVESESGPVKVGLTLCYDIRFPELYVELAERGAE
TH_0873|M.thermoresistible__bu FTESRTVAPGSEPVTIDV----GGVRVGLTTCYDIRFPELYVELARRGAE
MSMEG_0924|M.smegmatis_MC2_155 FTESRTVAPGFTPTTITVD----GTPVGITTCYDIRFPELYVELARRGAQ
* ** **:.* *. : * **:: ******* **.:** ***:
Rv0480c|M.tuberculosis_H37Rv LIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAAGQADPGDARTGVGA
Mb0490c|M.bovis_AF2122/97 LIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAAGQADPGDARTGVGA
MLBr_02449|M.leprae_Br4923 LIVVCASWGSGAGKLEQWTLLARARALDSMSYVAAVGQADPGGALTDSGP
MMAR_0805|M.marinum_M LIVVSASWGSGPGKLDQWTLLARARALDSASYVAAAGQADPGDTASDPGG
MUL_4548|M.ulcerans_Agy99 LIVVSASWGSGPGKLDQWTLLARARALDSASYVAAAGQADPGDTASDPGG
MAV_4670|M.avium_104 LIAVCASWGAGPGKLDQWTLLARARALDSMSYIAAAGQADPGGSLS----
MAB_4076|M.abscessus_ATCC_1997 VITVSASWAAGTGKWDQWTLLARARAADSTCFVAAADQALPALEAP----
Mflv_0095|M.gilvum_PYR-GCK IITAHASWGTGPGKLEQWTLLARARAIDTSSVVAAVGQAYPGDEIA----
Mvan_0813|M.vanbaalenii_PYR-1 IITAHASWGNGPGKIDQWTLLARARAIDTSTVVAAVGQAYPGDEIA----
TH_0873|M.thermoresistible__bu LLTVHASWGSGPGKLEQWTLLARARALDTTCVVAAVGQAYPGDEIA----
MSMEG_0924|M.smegmatis_MC2_155 LITVHASWGSGPGKLDQWTLLARARALDTTGYIAAVDQAYPGDEIA----
::.. ***. *.** :********** *: :**..** *. .
Rv0480c|M.tuberculosis_H37Rv SSAAPTGVGGSLVASPLGEVVVSAGTQPQLLVADIDVDNVAAARDRIAVL
Mb0490c|M.bovis_AF2122/97 SSAAPTGVGGSLVASPLGEVVVSAGTQPQLLVADIDVDNVAAARDRIAVL
MLBr_02449|M.leprae_Br4923 SSAAPTGVGGSLVASPLGEVVASAGTESKLVVADIDVDNVTTARENIAVL
MMAR_0805|M.marinum_M GSGAPRGVGGSLVASPLGEVVASAGSDPQLVVADIDLAKVGAARDNIGVL
MUL_4548|M.ulcerans_Agy99 GSGAPRGVGGSLVTSPLGEVVASAGSDPQLVVADIDLAKVGAARDNIGML
MAV_4670|M.avium_104 ASGAPTGVGGSLVASPLGEVVASAGAQPQLVLADIDVDRVAQARKTIAAL
MAB_4076|M.abscessus_ATCC_1997 AHGSPTGIGGSLLASPTGELIAQAGPDPELIVADLNLGAVAETRKILPVL
Mflv_0095|M.gilvum_PYR-GCK -ALGPTGVGGSLVASALGEVLASAGDDPELLVCDVDLEAARKARQTVAVM
Mvan_0813|M.vanbaalenii_PYR-1 -ALGPTGVGHSVVASALGEVLASAGADPQLLMCDIDLEAARAARQTVAVM
TH_0873|M.thermoresistible__bu -AQGPTGVGGSLVASATGEVLAAAGPEPELLVADLDLDAARRARDTIAVL
MSMEG_0924|M.smegmatis_MC2_155 -KAGPTGVGGSLVASPTGDVLASAGAEPELLTVDIDLDAATRVRDTVAIL
.* *:* *:::*. *:::. ** :.:*: *::: . .*. : :
Rv0480c|M.tuberculosis_H37Rv RNQTDFVQIDKAQSRG-------------------
Mb0490c|M.bovis_AF2122/97 RNQTDFVQIDKAQSRG-------------------
MLBr_02449|M.leprae_Br4923 RNRSHFA----------------------------
MMAR_0805|M.marinum_M RNQSRFTQTDKAQSRR-------------------
MUL_4548|M.ulcerans_Agy99 RNQSRFTQTDKAQSRR-------------------
MAV_4670|M.avium_104 SNRSDFAQVGRAESVG-------------------
MAB_4076|M.abscessus_ATCC_1997 NSSS-------AE----------------------
Mflv_0095|M.gilvum_PYR-GCK QNRSGFAHRGKAESRG-------------------
Mvan_0813|M.vanbaalenii_PYR-1 HNRSEAVRSSRERSSPAVRSSRERSSPAVRSSRER
TH_0873|M.thermoresistible__bu RNRSDVAQWGKAESVG-------------------
MSMEG_0924|M.smegmatis_MC2_155 DNRSALAGLS-------------------------
. :