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STTLIRGAWVLAPEPIRDGAVVIAGDRIAAVGTYTDLAAEYLGAAQHGSAHDIVGPGFVNTHGHFSEGLI TGIGSDFTLWEWIHTLIRPVDPHLDRRKAYLGTMVAGIQMLRSGVTTANDMFVCTPTGTPVSPGVVDALD ELGLRGVVSFGAGDVGGAPIAAQFDEHEALREAATASRLCTFRLGIGALGGQSDEMFARSVDYAVGGGHG VHIHVQEIREEVTATFARTGRTVVAHCAHEGLFAAPTLAAHCVWVDRNDRRILAEHRVGVAHNPVSNMIL ASGVAPVAEMRELGIDVGIGVDGPASNDSQDYLQALKTAALLARVHHRQATAMSAYEAWEMGTIGGARAL RMDDEIGSLEVGKKADVLVLDGRGPTLANVHDPYQAVVFVAGSREVSEVWVDGVPSVLGGDVVRVDPGEI AELSRPAAAELVTRAGLGHLSALVEA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3159 | - | - | 100% (447) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_3147 | - | 8e-91 | 42.64% (462) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_0863 | - | 5e-36 | 28.31% (484) | amidohydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2930 | - | 2e-06 | 26.19% (294) | amidohydrolase 3 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2927c | - | 6e-41 | 31.42% (436) | hydroxydechloroatrazine ethylaminohydrolase |
| M. marinum M | MMAR_2844 | - | 2e-32 | 29.03% (434) | metal-dependent hydrolase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1297 | - | 6e-42 | 32.72% (434) | hydroxydechloroatrazine ethylaminohydrolase |
| M. thermoresistible (build 8) | TH_3859 | - | 4e-13 | 23.94% (426) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2914 | - | 3e-31 | 28.80% (434) | hydroxydechloroatrazine ethylaminohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2844|M.marinum_M ------------------MSTILLTLMLECRVPKLVIDRVSIATVDPKAA
MUL_2914|M.ulcerans_Agy99 --------------------------MLECRVPKLVIDRISIATVDPKAA
MSMEG_1297|M.smegmatis_MC2_155 -------------------------------MPRLVIDGAAIATVDAAHT
MAB_2927c|M.abscessus_ATCC_199 ------------------------------MNPITLIENVFAATVDKSRR
Mvan_3159|M.vanbaalenii_PYR-1 -------------------------------MSTTLIRGAWVLAPEP---
TH_3859|M.thermoresistible__bu -----------------------------------------VLAGDPLTA
Mflv_2930|M.gilvum_PYR-GCK MCTACEWAPHFAAYGRRNPVTRRTALRAAAVTALAVTAAACATGPDSDTS
:
MMAR_2844|M.marinum_M EFSEGH--------------------------IIVEDDLIVAVGDG----
MUL_2914|M.ulcerans_Agy99 EFSEGH--------------------------IIVEDDLIVAVGDG----
MSMEG_1297|M.smegmatis_MC2_155 EHNRGY--------------------------IVVDDNIITAVGAG----
MAB_2927c|M.abscessus_ATCC_199 EIADAR--------------------------VVIEGGRIAAVLTAGENN
Mvan_3159|M.vanbaalenii_PYR-1 -IRDGA--------------------------VVIAGDRIAAVGTYT--D
TH_3859|M.thermoresistible__bu HVRAAD--------------------------LLIEDGRVTAIESD----
Mflv_2930|M.gilvum_PYR-GCK VTSAASGAEAPDFVFHNGRVYTVTESAPWAEAVVVTGNSITFVGDN-AAA
. ::: .. :. :
MMAR_2844|M.marinum_M PAPEVPGATVIDGRGCLATPGLVNTHEHLYQWITRGYTQKGTLFQWLTEM
MUL_2914|M.ulcerans_Agy99 PAPEVPGATVIDGRGCLATPGLVNTHEHLYQWITRGHTQKGTLFQWLTEM
MSMEG_1297|M.smegmatis_MC2_155 PAPEVPGAQFIDARGCLATPGLVNTHHHLYQWITRGHAQDGTLFEWLTTL
MAB_2927c|M.abscessus_ATCC_199 PWQELPGVERVDGSGCLLTPGLVNTHHHLYQWITRGLAADHTLFQWLTAL
Mvan_3159|M.vanbaalenii_PYR-1 LAAEYLGAAQHGSAHDIVGPGFVNTHGHFSEGLITGIGSDFTLWEWIHTL
TH_3859|M.thermoresistible__bu --LAGVDAEIIDATGRWVLPGFVDTHRHLWQTTMRGLTANWNLKDYFWCI
Mflv_2930|M.gilvum_PYR-GCK RALAGPDTEVIDLAGKLLMPGFVEGHIHPFLGSFLSTGVDLQVPTRQDAL
.. . **:*: * * . . : :
MMAR_2844|M.marinum_M Y-PVWGRLDAELEFAAASAGLAGLALTGCTTTMDHHYVFPHAG-------
MUL_2914|M.ulcerans_Agy99 Y-PVWGRLDAELEFAAASAGLAGLALTGCTTTMDHHYVFPHAG-------
MSMEG_1297|M.smegmatis_MC2_155 Y-PLWSHLDADLEYVAASAALAALALSGCTTTTDHHYVFPRGG-------
MAB_2927c|M.abscessus_ATCC_199 Y-PVWQGIDADSLHVAAQGALSWLALSGCTTTTDHHYVFPSDA-------
Mvan_3159|M.vanbaalenii_PYR-1 IRPVDPHLDRRKAYLGTMVAGIQMLRSGVTTANDMFVCTPTG--------
TH_3859|M.thermoresistible__bu RSHFAGLHDPDDVYGGQYAGGLDALVNGVTTTIDHSHITNSP--------
Mflv_2930|M.gilvum_PYR-GCK NAIAAYATDKADGPVRGFGWRVDMFGPQGPTRTELDSVLPDRPGFFFAID
* .* :
MMAR_2844|M.marinum_M GDMLGAEIAAAKRIGVR------------FHPTRGSMDLGVASGGLPPEH
MUL_2914|M.ulcerans_Agy99 GDMLGAEIVAAKRIGVR------------FHPTRGSMDLGVASGGLPPEH
MSMEG_1297|M.smegmatis_MC2_155 GDVLGAEIAAAQRIGLR------------FHPTRGSMDLGASAGGLPPDN
MAB_2927c|M.abscessus_ATCC_199 GDLLEAEIEAARQVGLR------------FDPTRGSMDLGRSAGGLPPDG
Mvan_3159|M.vanbaalenii_PYR-1 TPVSPGVVDALDELGLR------------GVVSFGAGDVGGAP-------
TH_3859|M.thermoresistible__bu -DHSDAAVRGLLDSGVR------------ALWCYGFYPSPQADP------
Mflv_2930|M.gilvum_PYR-GCK GHSMWANSKALEMAGISRDSEDPIPGFSYYVRDENGEPTGYVLEVDAVLG
. . *: .
MMAR_2844|M.marinum_M TVEDIDTILTTCQDAVREHHDPTKGSMVQISLAPCSPFSVTGE-----LM
MUL_2914|M.ulcerans_Agy99 TVEDIDTILTTCQDAVREHHDPTKGSMVQISLAPCSPFSVTGE-----LM
MSMEG_1297|M.smegmatis_MC2_155 VVEDIDAILAAGQDAVGAHHDPSFGSMCRIALAPCSPFSVSGE-----LM
MAB_2927c|M.abscessus_ATCC_199 LVESIDTALEASDAAIARWHDPAPGAMVRIGLAPCSPFSVSAD-----LL
Mvan_3159|M.vanbaalenii_PYR-1 -------IAAQFDEHEALREAATASRLCTFRLGIGALGGQSDE-----MF
TH_3859|M.thermoresistible__bu -VFTTPQHRLDDARRVRSTFFPTDDGLVRMGVALTELGMQPFT-----ET
Mflv_2930|M.gilvum_PYR-GCK LVNAIEPISTDSMEQLLRAWLPKASEAGITSVFDAGVPPIGGDQGALIEL
. . :
MMAR_2844|M.marinum_M KQSALLARDLGVRLHTHLSETVEEDEFCLAQFG------SRPVDYVESLG
MUL_2914|M.ulcerans_Agy99 KQSALLARDLGVRLHTHLSETVEEDEFCLAQFG------SRPVDYVESLG
MSMEG_1297|M.smegmatis_MC2_155 RESAALARELGVRLHTHIAETTDEEQFCLERFG------ARPVDYVESLG
MAB_2927c|M.abscessus_ATCC_199 RQSALLARERGVRLHTHLAETKDESVYCAERFG------CSPLDYMEELG
Mvan_3159|M.vanbaalenii_PYR-1 ARSVDYAVGGGHGVHIHVQEIREEVTATFARTG------RTVVAHCAHEG
TH_3859|M.thermoresistible__bu QRELQTAEDLAVPVTMHT-------NCVWTRPE------FHDVELYHRAG
Mflv_2930|M.gilvum_PYR-GCK YTNVESRGELPFRVVASYSVKSPPVDDAVAELTGIRDRISSDLVQVNVVK
. : . :
MMAR_2844|M.marinum_M WLGSDVWMAHCVHLSKGDIAKLAATG------------TGVAHCPTSNGR
MUL_2914|M.ulcerans_Agy99 WLGSDVWMAHCVHLSKGYIAKLAATG------------TGVAHCPTSNGR
MSMEG_1297|M.smegmatis_MC2_155 WLGDDVWFAHGVHLSASDIAKLAQTG------------TGVAHCPSSNAR
MAB_2927c|M.abscessus_ATCC_199 WLGPDVWFAHGVHFDDASIARLARTG------------TGIAHCPTSNGR
Mvan_3159|M.vanbaalenii_PYR-1 LFAAPTLAAHCVWVDRNDRRILAEHR------------VGVAHNPVSNMI
TH_3859|M.thermoresistible__bu LLRAGQIHSHANRCSDHELALLRDAG------------CAVSSTPDTELQ
Mflv_2930|M.gilvum_PYR-GCK IIGDGTQEGYTAWLLEPYADKPDSIGGSPFTDDQWRQLVREVDAAGFDVH
: .: . :
MMAR_2844|M.marinum_M FGAGIAPIPELLAADVAVGLGVDGAG--------------AEHRGLANEM
MUL_2914|M.ulcerans_Agy99 FGAGIAPIPELLAADVAVGLGVDGAG--------------AEHRGLANEM
MSMEG_1297|M.smegmatis_MC2_155 LGAGTAPIPELLAAGVPVGMGVDGVAS-------------NEHGGLGGEL
MAB_2927c|M.abscessus_ATCC_199 LGAGIARVRELLAAGVPVGLGVDGAAS-------------NESGRLLEEA
Mvan_3159|M.vanbaalenii_PYR-1 LASGVAPVAEMRELGIDVGIGVDGPAS-------------NDSQDYLQAL
TH_3859|M.thermoresistible__bu MGCGRPVFRRALATGVTAGIGIDIVS--------------NNSGDMFTAM
Mflv_2930|M.gilvum_PYR-GCK IHACGERTARTALDSIEAAAKVNPARERRHTVAHLVYLEEPDSRRFGDLG
: . . .: .. :: :
MMAR_2844|M.marinum_M RQAALAAR-------------FRLG-PQALDAREALWMATVGGARCLGRD
MUL_2914|M.ulcerans_Agy99 RQAALAAR-------------FRLG-PQALDAREALWMATVGGARCLGRD
MSMEG_1297|M.smegmatis_MC2_155 RQALLMAR-------------NRLG-PTAITARQVLQAGTIGGARCLGRD
MAB_2927c|M.abscessus_ATCC_199 HQALLLAR-------------AVGG-PTALSTRTALELATLGGARLLGRS
Mvan_3159|M.vanbaalenii_PYR-1 KTAALLAR-------------VHHRQATAMSAYEAWEMGTIGGARALRMD
TH_3859|M.thermoresistible__bu RVLMQHERGDALQPTLEESGLTAVAEPLPVTTRQILHAATLAGARALGLE
Mflv_2930|M.gilvum_PYR-GCK VIAEFSANWFSADPDTVINLAARYGAPRKDNLYRIQDVLSSGGRVSLGTD
. . : .* * .
MMAR_2844|M.marinum_M QDLG----------SLEVGKLADIALWQLDGLG-----HSDVEDPVWALI
MUL_2914|M.ulcerans_Agy99 QDLG----------SLEVGKLADIALWQLDGLG-----HSDVEDPVWALI
MSMEG_1297|M.smegmatis_MC2_155 RELG----------SLEPGKLADMALWRVDGLG-----HADIDDPVCALV
MAB_2927c|M.abscessus_ATCC_199 DEIG----------SIEVGKCADLVLWDLSTLG-----HSGIEDPVAAVI
Mvan_3159|M.vanbaalenii_PYR-1 DEIG----------SLEVGKKADVLVLDGRGPT-----LANVHDPYQAVV
TH_3859|M.thermoresistible__bu SVCG----------SIDVGKSADLLLLRHDRLH-----MRPVIDDIDSIV
Mflv_2930|M.gilvum_PYR-GCK WPAAGYFSTYKPLDSIQIGVTRQLIGDPAAEVLSPADQKLTVEQAVHANT
. *:: * :: : : :
MMAR_2844|M.marinum_M YGPPAP-LRLLLVGGNTVVEDGELRTADTETLATDAKNAAVTLRERG---
MUL_2914|M.ulcerans_Agy99 YGPPAP-LRLLLVGGNTVVEDGELRTADTETLATDAKNAAVTLRERG---
MSMEG_1297|M.smegmatis_MC2_155 FGPSAP-LRLLLVNGVPVVADDELRTADTATLAGDARDAARTLRARAGT-
MAB_2927c|M.abscessus_ATCC_199 LGEVPP-IRRSWVGGRPIVADGQMLTVDTERIAVAVRAAHHGLMNRER--
Mvan_3159|M.vanbaalenii_PYR-1 FVAGSREVSEVWVDGVPSVLGGDVVRVDPGEIAELSRPAAAELVTRAGLG
TH_3859|M.thermoresistible__bu LQATTRDIDRVLVAGRTVVQDGRLPAAVERRGVAAIEAAHSRLAERVAAV
Mflv_2930|M.gilvum_PYR-GCK LGAAYQLRLDGLVGSVETGKRADLIVVDRNIFEIDPHDIHSAAVTLTMMD
* . : . .
MMAR_2844|M.marinum_M --------------------------------
MUL_2914|M.ulcerans_Agy99 --------------------------------
MSMEG_1297|M.smegmatis_MC2_155 --------------------------------
MAB_2927c|M.abscessus_ATCC_199 --------------------------------
Mvan_3159|M.vanbaalenii_PYR-1 HLSALVEA------------------------
TH_3859|M.thermoresistible__bu GGWKLAVPQGLMDQLGVTFHDNVANTPAQANS
Mflv_2930|M.gilvum_PYR-GCK GEIRHRV-------------------------