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M. thermoresistible (build 8) TH_3859 (-)

annotation: -
coordinates: 571550 - 572968
length: 473

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3859--100% (473)-

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1416pyrC4e-0755.81% (43) dihydroorotase
M. gilvum PYR-GCKMflv_3746pyrC5e-0550.00% (44) dihydroorotase
M. tuberculosis H37RvRv1381pyrC4e-0755.81% (43) dihydroorotase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2927c-2e-2827.41% (467) hydroxydechloroatrazine ethylaminohydrolase
M. marinum MMMAR_2844-8e-2326.35% (444) metal-dependent hydrolase
M. avium 104MAV_3392pyrC7e-0643.86% (57) dihydroorotase
M. smegmatis MC2 155MSMEG_1297-1e-2125.29% (431) hydroxydechloroatrazine ethylaminohydrolase
M. ulcerans Agy99MUL_2914-3e-2226.35% (444) hydroxydechloroatrazine ethylaminohydrolase
M. vanbaalenii PYR-1Mvan_3147-1e-2326.53% (441) amidohydrolase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1416|M.bovis_AF2122/97            ---------------------MSVLIRGVRPYG-EGERVDVLVDDGQIAQ
Rv1381|M.tuberculosis_H37Rv         ---------------------MSVLIRGVRPYG-EGERVDVLVDDGQIAQ
MAV_3392|M.avium_104                ---------------------MSVLLRGVRLYG-EGDRVDVLVDDGQIAD
Mflv_3746|M.gilvum_PYR-GCK          ---------------------MSVVLKSVRLYG-EGDAVDVLVRDGIIAE
MMAR_2844|M.marinum_M               --MSTILLTLMLECRVPKLVIDRVSIATVDPKAAEFSEGHIIVEDDLIVA
MUL_2914|M.ulcerans_Agy99           ----------MLECRVPKLVIDRISIATVDPKAAEFSEGHIIVEDDLIVA
MSMEG_1297|M.smegmatis_MC2_155      ---------------MPRLVIDGAAIATVDAAHTEHNRGYIVVDDNIITA
MAB_2927c|M.abscessus_ATCC_199      --------------MNPITLIENVFAATVDKSRREIADARVVIEGGRIAA
Mvan_3147|M.vanbaalenii_PYR-1       MTEFLVRGRYVLSMAGLPAPAERVRTPGAHLDG-VLTDAAVHVRDGAIVA
TH_3859|M.thermoresistible__bu      -------------------------VLAGDPLTAHVRAADLLIEDGRVTA
                                                                            : : .. :. 

Mb1416|M.bovis_AF2122/97            IGPD-----LAIPDTADVIDATGH-VLLPGFVDLHTHLREPGREYAEDIE
Rv1381|M.tuberculosis_H37Rv         IGPD-----LAIPDTADVIDATGH-VLLPGFVDLHTHLREPGREYAEDIE
MAV_3392|M.avium_104                IGAG-----LDIPDTADVIDATGQ-VLLPGFVDLHTHLREPGREYAEDIE
Mflv_3746|M.gilvum_PYR-GCK          IGTG-----LSADET---IDCTGR-VLLPGFVDLHTHLREPGREYAEDIE
MMAR_2844|M.marinum_M               VGDG----PAPEVPGATVIDGRGC-LATPGLVNTHEHLYQ--WITRGYTQ
MUL_2914|M.ulcerans_Agy99           VGDG----PAPEVPGATVIDGRGC-LATPGLVNTHEHLYQ--WITRGHTQ
MSMEG_1297|M.smegmatis_MC2_155      VGAG----PAPEVPGAQFIDARGC-LATPGLVNTHHHLYQ--WITRGHAQ
MAB_2927c|M.abscessus_ATCC_199      VLTAGENNPWQELPGVERVDGSGC-LLTPGLVNTHHHLYQ--WITRGLAA
Mvan_3147|M.vanbaalenii_PYR-1       VDGY---AALVAAQAHLPVHGDGTGLVIPGLISTHTHLSES--LATGMGS
TH_3859|M.thermoresistible__bu      IESD------LAGVDAEIIDATGR-WVLPGFVDTHRHLWQT--TMRGLTA
                                    :                 :.  *     **::. * ** :          

Mb1416|M.bovis_AF2122/97            TGSAAAALGGYTAVFAMANTNPVADSPVVTDHVWHRGQQVGLVDVHPVGA
Rv1381|M.tuberculosis_H37Rv         TGSAAAALGGYTAVFAMANTNPVADSPVVTDHVWHRGQQVGLVDVHPVGA
MAV_3392|M.avium_104                TGSAAAALGGYTAVFAMANTNPVADSPVVTDHVWHRGQQVGLVDVHPVGA
Mflv_3746|M.gilvum_PYR-GCK          TGSAAAALGGYTAVFAMANTDPVADSVVVTDHVWQRGQQVGLVDVHPVGA
MMAR_2844|M.marinum_M               KGTLFQWLTEMYPVWGRLDAELEFAAASAGLAGLALTGCTTTMDHHYVFP
MUL_2914|M.ulcerans_Agy99           KGTLFQWLTEMYPVWGRLDAELEFAAASAGLAGLALTGCTTTMDHHYVFP
MSMEG_1297|M.smegmatis_MC2_155      DGTLFEWLTTLYPLWSHLDADLEYVAASAALAALALSGCTTTTDHHYVFP
MAB_2927c|M.abscessus_ATCC_199      DHTLFQWLTALYPVWQGIDADSLHVAAQGALSWLALSGCTTTTDHHYVFP
Mvan_3147|M.vanbaalenii_PYR-1       ELSLFEWADAIVAPLGMVLTREDAAEGTALRAIEMLLSGVTTVNDMFCHT
TH_3859|M.thermoresistible__bu      NWNLKDYFWCIRSHFAGLHDPDDVYGGQYAGGLDALVNGVTTTIDHSHIT
                                      .         .                          .         .

Mb1416|M.bovis_AF2122/97            VTVG-LAGAELTEMGMMNAGAAQVRMFSDDGVCVHDPLIMRRALEYATGL
Rv1381|M.tuberculosis_H37Rv         VTVG-LAGAELTEMGMMNAGAAQVRMFSDDGVCVHDPLIMRRALEYATGL
MAV_3392|M.avium_104                VTMG-LAGKELTEMGMMAAGAAQVRMFSDDGVCVHDPLVMRRALEYATGL
Mflv_3746|M.gilvum_PYR-GCK          VTVG-LAGKQLTEMGLMAAGTGRVRMFSDDGVCVDDPLLMRRALEYASGL
MMAR_2844|M.marinum_M               HAGGDMLGAEIAAAKRIGVRFHPTRGSMDLGVASGGLPPEHTVEDIDTIL
MUL_2914|M.ulcerans_Agy99           HAGGDMLGAEIVAAKRIGVRFHPTRGSMDLGVASGGLPPEHTVEDIDTIL
MSMEG_1297|M.smegmatis_MC2_155      RGGGDVLGAEIAAAQRIGLRFHPTRGSMDLGASAGGLPPDNVVEDIDAIL
MAB_2927c|M.abscessus_ATCC_199      SDAGDLLEAEIEAARQVGLRFDPTRGSMDLGRSAGGLPPDGLVESIDTAL
Mvan_3147|M.vanbaalenii_PYR-1       -----NIGSRASLGVVDGLTRAGMRGVVAYGAEDLPLLERSTLAPGDVID
TH_3859|M.thermoresistible__bu      N------SPDHSDAAVRGLLDSGVRALWCYGFYPSPQADPVFTTPQHRLD
                                                            *     *                   

Mb1416|M.bovis_AF2122/97            GVLIAQHAEEPRLTVGAFAHEGPMAARLGLAGWPRAAEESIVARDALLAR
Rv1381|M.tuberculosis_H37Rv         GVLIAQHAEEPRLTVGAVAHEGPMAARLGLAGWPRAAEESIVARDALLAR
MAV_3392|M.avium_104                GVLIAQHAEEPRLTVGAVAHEGPTAARLGLAGWPRAAEESIVARDALLAR
Mflv_3746|M.gilvum_PYR-GCK          GVLIAQHAEEPRLTVGAVAHEGPNAARLGLAGWPRAAEESIVARDALLAR
MMAR_2844|M.marinum_M               TTCQDAVREHHDPTKGSMVQISLAPCS------PFSVTGELMKQSALLAR
MUL_2914|M.ulcerans_Agy99           TTCQDAVREHHDPTKGSMVQISLAPCS------PFSVTGELMKQSALLAR
MSMEG_1297|M.smegmatis_MC2_155      AAGQDAVGAHHDPSFGSMCRIALAPCS------PFSVSGELMRESAALAR
MAB_2927c|M.abscessus_ATCC_199      EASDAAIARWHDPAPGAMVRIGLAPCS------PFSVSADLLRQSALLAR
Mvan_3147|M.vanbaalenii_PYR-1       DVLAEQHDLAAHAATAPLLDFRYGVGT------LLGQSDELLAAGVEECR
TH_3859|M.thermoresistible__bu      DARRVRSTFFP--TDDGLVRMGVALTELG--MQPFTETQRELQTAEDLAV
                                     .           :   .                       :      . 

Mb1416|M.bovis_AF2122/97            DAGARVHICHASAAGTVEILKWAKDQGISITAEVTPHHLLLDDARLASYD
Rv1381|M.tuberculosis_H37Rv         DAGARVHICHASAAGTVEILKWAKDQGISITAEVTPHHLLLDDARLASYD
MAV_3392|M.avium_104                DAGARVHICHASTAGTVEIVKWAKQQGISITAEVTPHHLMLDDSRLASYD
Mflv_3746|M.gilvum_PYR-GCK          DAGARVHICHASTAGTVELVRWAKEQGIAITAEVTPHHLLLDDTRLETYD
MMAR_2844|M.marinum_M               DLGVRLHTHLSETV--EEDEFCLAQFGSRPVDYVESLGWLGSDVWMAHCV
MUL_2914|M.ulcerans_Agy99           DLGVRLHTHLSETV--EEDEFCLAQFGSRPVDYVESLGWLGSDVWMAHCV
MSMEG_1297|M.smegmatis_MC2_155      ELGVRLHTHIAETT--DEEQFCLERFGARPVDYVESLGWLGDDVWFAHGV
MAB_2927c|M.abscessus_ATCC_199      ERGVRLHTHLAETK--DESVYCAERFGCSPLDYMEELGWLGPDVWFAHGV
Mvan_3147|M.vanbaalenii_PYR-1       RAGWGVHTHLAEVR--EEVTTARHRWGHRTVEHSLRAGLFERPLIAGHGV
TH_3859|M.thermoresistible__bu      P--VTMHTNCVWTR-----------PEFHDVELYHRAGLLRAGQIHSHAN
                                         :*     .                          :          

Mb1416|M.bovis_AF2122/97            GVNRVNPPLREASDAVALRQALADGIIDCVATDHAPHAEHEKCVEFAAAR
Rv1381|M.tuberculosis_H37Rv         GVNRVNPPLREASDAVALRQALADGIIDCVATDHAPHAEHEKCVEFAAAR
MAV_3392|M.avium_104                GRNRVNPPLREAADAAALRRALADGVIDCVATDHAPHAEHEKCVEFSAAR
Mflv_3746|M.gilvum_PYR-GCK          GRNRVNPPLREVSDTLALRQALADGVIDCVATDHAPHGEHEKMCEFANAR
MMAR_2844|M.marinum_M               HLSKGDIAKLAATGTGVAHCPTSNGRFGAGIAPIPELLAADVAVGLGVDG
MUL_2914|M.ulcerans_Agy99           HLSKGYIAKLAATGTGVAHCPTSNGRFGAGIAPIPELLAADVAVGLGVDG
MSMEG_1297|M.smegmatis_MC2_155      HLSASDIAKLAQTGTGVAHCPSSNARLGAGTAPIPELLAAGVPVGMGVDG
MAB_2927c|M.abscessus_ATCC_199      HFDDASIARLARTGTGIAHCPTSNGRLGAGIARVRELLAAGVPVGLGVDG
Mvan_3147|M.vanbaalenii_PYR-1       WLTEADIATFARHGAAIAHNPVANMILASGVCPVPRLRAAGVPVGIGTDG
TH_3859|M.thermoresistible__bu      RCSDHELALLRDAGCAVSSTPDTELQMGCGRPVFRRALATGVTAGIGIDI
                                           .     .      . ::  : .                :.   

Mb1416|M.bovis_AF2122/97            PG------MLGLQTALSVVVQT-MVAPGL-------------LSWRDIAR
Rv1381|M.tuberculosis_H37Rv         PG------MLGLQTALSVVVQT-MVAPGL-------------LSWRDIAR
MAV_3392|M.avium_104                PG------MLGLQTALSIVVHT-MVRPGL-------------LTWRDVAK
Mflv_3746|M.gilvum_PYR-GCK          PG------MLGLQTALSVVVET-MVQPGP-------------LTWRDVAR
MMAR_2844|M.marinum_M               AG-AEHRGLANEMRQAALAARF-RLGPQA-------------LDAREALW
MUL_2914|M.ulcerans_Agy99           AG-AEHRGLANEMRQAALAARF-RLGPQA-------------LDAREALW
MSMEG_1297|M.smegmatis_MC2_155      VASNEHGGLGGELRQALLMARN-RLGPTA-------------ITARQVLQ
MAB_2927c|M.abscessus_ATCC_199      AASNESGRLLEEAHQALLLARA-VGGPTA-------------LSTRTALE
Mvan_3147|M.vanbaalenii_PYR-1       AASNDSQDMLQAVKAAALLQKVHHLDALV-------------VDALDVLT
TH_3859|M.thermoresistible__bu      VS-NNSGDMFTAMRVLMQHERGDALQPTLEESGLTAVAEPLPVTTRQILH
                                     .      :           .     .               :       

Mb1416|M.bovis_AF2122/97            VMSENPACIARLPDQGRPLEVGEPANLTVVDPDATWTVTGADLASRSANT
Rv1381|M.tuberculosis_H37Rv         VMSENPACIARLPDQGRPLEVGEPANLTVVDPDATWTVTGADLASRSANT
MAV_3392|M.avium_104                VMSENPARIANLPDHGRPLEVGEPANLTVVDPDASWTVAGSDLASRSANT
Mflv_3746|M.gilvum_PYR-GCK          VMSEAPARIVGLPDQGRPLEVGEPANLTVVDPDARWTVSGPALASRSDNT
MMAR_2844|M.marinum_M               MATVGGARCLGRDQDLGSLEVGKLADIALWQLDGLGHSDVEDPVWALIYG
MUL_2914|M.ulcerans_Agy99           MATVGGARCLGRDQDLGSLEVGKLADIALWQLDGLGHSDVEDPVWALIYG
MSMEG_1297|M.smegmatis_MC2_155      AGTIGGARCLGRDRELGSLEPGKLADMALWRVDGLGHADIDDPVCALVFG
MAB_2927c|M.abscessus_ATCC_199      LATLGGARLLGRSDEIGSIEVGKCADLVLWDLSTLGHSGIEDPVAAVILG
Mvan_3147|M.vanbaalenii_PYR-1       MATIDGARALGLDHLVGSLEPGKRADIVLLQ-DTVDVAVLHDPVAQLVYG
TH_3859|M.thermoresistible__bu      AATLAGARALGLESVCGSIDVGKSADLLLLRHDRLHMRPVIDDIDSIVLQ
                                      :   *          .:: *: *:: :   .                 

Mb1416|M.bovis_AF2122/97            P-FESMSLPATVTATLLR-GKVTARDGKIRA-------------------
Rv1381|M.tuberculosis_H37Rv         P-FESMSLPATVTATLLR-GKVTARDGKIRA-------------------
MAV_3392|M.avium_104                P-YEAMTLPATVTATLLR-GKVTARDGKCPV-------------------
Mflv_3746|M.gilvum_PYR-GCK          P-YEAMELPGVVTATLLR-GTVTARDGKAGA-------------------
MMAR_2844|M.marinum_M               P-PAPLRLLLVGGNTVVEDGELRTADTETLATDAKNAAVTLRERG-----
MUL_2914|M.ulcerans_Agy99           P-PAPLRLLLVGGNTVVEDGELRTADTETLATDAKNAAVTLRERG-----
MSMEG_1297|M.smegmatis_MC2_155      P-SAPLRLLLVNGVPVVADDELRTADTATLAGDARDAARTLRARAGT---
MAB_2927c|M.abscessus_ATCC_199      E-VPPIRRSWVGGRPIVADGQMLTVDTERIAVAVRAAHHGLMNRER----
Mvan_3147|M.vanbaalenii_PYR-1       ASPRSVRDVWVDGVQVVADHRCTTVDEATQIARCRPLADRVGVKAGLVAT
TH_3859|M.thermoresistible__bu      ATTRDIDRVLVAGRTVVQDGRLPAAVERRGVAAIEAAHSRLAERVAAVGG
                                         :    .    ::      :                          

Mb1416|M.bovis_AF2122/97            ------------------------------
Rv1381|M.tuberculosis_H37Rv         ------------------------------
MAV_3392|M.avium_104                ------------------------------
Mflv_3746|M.gilvum_PYR-GCK          ------------------------------
MMAR_2844|M.marinum_M               ------------------------------
MUL_2914|M.ulcerans_Agy99           ------------------------------
MSMEG_1297|M.smegmatis_MC2_155      ------------------------------
MAB_2927c|M.abscessus_ATCC_199      ------------------------------
Mvan_3147|M.vanbaalenii_PYR-1       GHSVVTG-----------------------
TH_3859|M.thermoresistible__bu      WKLAVPQGLMDQLGVTFHDNVANTPAQANS