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VPRLVIDGAAIATVDAAHTEHNRGYIVVDDNIITAVGAGPAPEVPGAQFIDARGCLATPGLVNTHHHLYQ WITRGHAQDGTLFEWLTTLYPLWSHLDADLEYVAASAALAALALSGCTTTTDHHYVFPRGGGDVLGAEIA AAQRIGLRFHPTRGSMDLGASAGGLPPDNVVEDIDAILAAGQDAVGAHHDPSFGSMCRIALAPCSPFSVS GELMRESAALARELGVRLHTHIAETTDEEQFCLERFGARPVDYVESLGWLGDDVWFAHGVHLSASDIAKL AQTGTGVAHCPSSNARLGAGTAPIPELLAAGVPVGMGVDGVASNEHGGLGGELRQALLMARNRLGPTAIT ARQVLQAGTIGGARCLGRDRELGSLEPGKLADMALWRVDGLGHADIDDPVCALVFGPSAPLRLLLVNGVP VVADDELRTADTATLAGDARDAARTLRARAGT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1297 | - | - | 100% (452) | hydroxydechloroatrazine ethylaminohydrolase |
| M. smegmatis MC2 155 | MSMEG_1181 | hutF | 5e-28 | 29.34% (426) | N-formimino-L-glutamate deiminase |
| M. smegmatis MC2 155 | MSMEG_1298 | - | 3e-26 | 28.96% (404) | guanine deaminase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2078c | - | 6e-05 | 31.78% (107) | hypothetical protein Mb2078c |
| M. gilvum PYR-GCK | Mflv_2466 | - | 3e-07 | 26.24% (465) | amidohydrolase |
| M. tuberculosis H37Rv | Rv2052c | - | 6e-05 | 31.78% (107) | hypothetical protein Rv2052c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2927c | - | 1e-151 | 58.63% (452) | hydroxydechloroatrazine ethylaminohydrolase |
| M. marinum M | MMAR_2844 | - | 0.0 | 71.05% (449) | metal-dependent hydrolase |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3859 | - | 7e-22 | 25.29% (431) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2914 | - | 0.0 | 70.82% (449) | hydroxydechloroatrazine ethylaminohydrolase |
| M. vanbaalenii PYR-1 | Mvan_3147 | - | 2e-46 | 34.48% (464) | amidohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2844|M.marinum_M -MSTILLTLMLECRVPKLVIDRVSIATVDPKAAEFSEGHIIVEDDLIVAV
MUL_2914|M.ulcerans_Agy99 ---------MLECRVPKLVIDRISIATVDPKAAEFSEGHIIVEDDLIVAV
MSMEG_1297|M.smegmatis_MC2_155 --------------MPRLVIDGAAIATVDAAHTEHNRGYIVVDDNIITAV
MAB_2927c|M.abscessus_ATCC_199 -------------MNPITLIENVFAATVDKSRREIADARVVIEGGRIAAV
Mb2078c|M.bovis_AF2122/97 ----------MSQIPVKLLVNGRVYSPTHPEATAMAVRGDVVAWLGSDDV
Rv2052c|M.tuberculosis_H37Rv ----------MSQIPVKLLVNGRVYSPTHPEATAMAVRGDVVAWLGSDDV
Mvan_3147|M.vanbaalenii_PYR-1 MTEFLVRGRYVLSMAGLPAPAERVRTPGAHLDGVLTDAAVHVRDGAIVAV
TH_3859|M.thermoresistible__bu ------------------------VLAGDPLTAHVRAADLLIEDGRVTAI
Mflv_2466|M.gilvum_PYR-GCK ---------------MTVTVVKAARWADVEAGVVRSPAVIVVEGNRIRSV
. : :
MMAR_2844|M.marinum_M GDG----PAPEVPGATVIDGRGC-LATPGLVNTHEHLYQW------ITRG
MUL_2914|M.ulcerans_Agy99 GDG----PAPEVPGATVIDGRGC-LATPGLVNTHEHLYQW------ITRG
MSMEG_1297|M.smegmatis_MC2_155 GAG----PAPEVPGAQFIDARGC-LATPGLVNTHHHLYQW------ITRG
MAB_2927c|M.abscessus_ATCC_199 LTAGENNPWQELPGVERVDGSGC-LLTPGLVNTHHHLYQW------ITRG
Mb2078c|M.bovis_AF2122/97 GRD-------QFPDADVQDLDGR-FVAPGFVDSHIHLTATGLMLSGLDLR
Rv2052c|M.tuberculosis_H37Rv GRD-------QFPDADVQDLDGR-FVAPGFVDSHIHLTATGLMLSGLDLR
Mvan_3147|M.vanbaalenii_PYR-1 DGY---AALVAAQAHLPVHGDGTGLVIPGLISTHTHLSES------LATG
TH_3859|M.thermoresistible__bu ESD------LAGVDAEIIDATGR-WVLPGFVDTHRHLWQT------TMRG
Mflv_2466|M.gilvum_PYR-GCK DPA------AEPPGAEVLDLGDV-TLLPGLMDMELNLLIG---------G
. . **::. . :*
MMAR_2844|M.marinum_M YTQKGTLFQWLTEMY-------PVWGR---LDAELEFAAASAGLAGLALT
MUL_2914|M.ulcerans_Agy99 HTQKGTLFQWLTEMY-------PVWGR---LDAELEFAAASAGLAGLALT
MSMEG_1297|M.smegmatis_MC2_155 HAQDGTLFEWLTTLY-------PLWSH---LDADLEYVAASAALAALALS
MAB_2927c|M.abscessus_ATCC_199 LAADHTLFQWLTALY-------PVWQG---IDADSLHVAAQGALSWLALS
Mb2078c|M.bovis_AF2122/97 PATSRAQCLRMVADYAADHPGQPLWGHGWDESAWPENAAPSTADLDAVLG
Rv2052c|M.tuberculosis_H37Rv PATSRAQCLRMVADYAADHPGQPLWGHGWDESAWPENAAPSTADLDAVLG
Mvan_3147|M.vanbaalenii_PYR-1 MGSELSLFEWADAIVA------PLGMV---LTREDAAEGTALRAIEMLLS
TH_3859|M.thermoresistible__bu LTANWNLKDYFWCIR-------SHFAG--LHDPDDVYGGQYAGGLDALVN
Mflv_2466|M.gilvum_PYR-GCK PGGPEGLPSPMHGVQ---------------DDPAYRTLRGAVNARTTLDA
MMAR_2844|M.marinum_M GCTT---TMDHHYVFPHAGGDMLGAEIAAAKRIGVRFHPTRGSMDLGVAS
MUL_2914|M.ulcerans_Agy99 GCTT---TMDHHYVFPHAGGDMLGAEIVAAKRIGVRFHPTRGSMDLGVAS
MSMEG_1297|M.smegmatis_MC2_155 GCTT---TTDHHYVFPRGGGDVLGAEIAAAQRIGLRFHPTRGSMDLGASA
MAB_2927c|M.abscessus_ATCC_199 GCTT---TTDHHYVFPSDAGDLLEAEIEAARQVGLRFDPTRGSMDLGRSA
Mb2078c|M.bovis_AF2122/97 DCPAYLARIDSHSALVSSGLRRLVPELAAATGYTAQRPLTGDAHHLARAA
Rv2052c|M.tuberculosis_H37Rv DCPAYLARIDSHSALVSSGLRRLVPELAAATGYTAQRPLTGDAHHLARAA
Mvan_3147|M.vanbaalenii_PYR-1 GVTT----VNDMFCHTNIGSRASLGVVDGLTRAGMRGVVAYGAEDLPLLE
TH_3859|M.thermoresistible__bu GVTT---TIDHSHITNSP--DHSDAAVRGLLDSGVRALWCYGFYPSPQAD
Mflv_2466|M.gilvum_PYR-GCK GFTT----VRNLGLMVKTGGYLLDVALQRAIEQGWHPGPRIYPAGHAVTP
. .: : :
MMAR_2844|M.marinum_M G------GLPPEHTVEDIDTILTTCQDAVREHHDPTKG--------SMVQ
MUL_2914|M.ulcerans_Agy99 G------GLPPEHTVEDIDTILTTCQDAVREHHDPTKG--------SMVQ
MSMEG_1297|M.smegmatis_MC2_155 G------GLPPDNVVEDIDAILAAGQDAVGAHHDPSFG--------SMCR
MAB_2927c|M.abscessus_ATCC_199 G------GLPPDGLVESIDTALEASDAAIARWHDPAPG--------AMVR
Mb2078c|M.bovis_AF2122/97 ARYLLTDVQLADARAVALQAIAAAGVVAVHECAGPEIGGLDDWLRLRALE
Rv2052c|M.tuberculosis_H37Rv ARYLLTDVQLADARAVALQAIAAAGVVAVHECAGPEIGGLDDWLRLRALE
Mvan_3147|M.vanbaalenii_PYR-1 R-----STLAPG---DVIDDVLAEQHDLAAHAATAP-----------LLD
TH_3859|M.thermoresistible__bu P------------VFTTPQHRLDDARRVRSTFFPTDDG---------LVR
Mflv_2466|M.gilvum_PYR-GCK YG-------------GHLDPTVFQRLAPGIMPLSVAEG------------
:
MMAR_2844|M.marinum_M ISLAPCSPFSVTGELMKQSALLARDLGVR------------------LHT
MUL_2914|M.ulcerans_Agy99 ISLAPCSPFSVTGELMKQSALLARDLGVR------------------LHT
MSMEG_1297|M.smegmatis_MC2_155 IALAPCSPFSVSGELMRESAALARELGVR------------------LHT
MAB_2927c|M.abscessus_ATCC_199 IGLAPCSPFSVSADLLRQSALLARERGVR------------------LHT
Mb2078c|M.bovis_AF2122/97 HGVEVIGYWGEAVATPAQARDLVTETGARGLAGDLFVDGALGSRTAWLHE
Rv2052c|M.tuberculosis_H37Rv HGVEVIGYWGEAVATPAQARDLVTETGARGLAGDLFVDGALGSRTAWLHE
Mvan_3147|M.vanbaalenii_PYR-1 FRYGVGTLLGQSDELLAAGVEECRRAGWG------------------VHT
TH_3859|M.thermoresistible__bu MGVALTELGMQPFTETQRELQTAEDLAVP---------------------
Mflv_2466|M.gilvum_PYR-GCK IANGVDDVRACVRYQVRHGAKLIKVSASG---------------------
.
MMAR_2844|M.marinum_M HLSETVEEDEFCLAQFG--------SRPVDYVESLGWLGSDVWMAHCVHL
MUL_2914|M.ulcerans_Agy99 HLSETVEEDEFCLAQFG--------SRPVDYVESLGWLGSDVWMAHCVHL
MSMEG_1297|M.smegmatis_MC2_155 HIAETTDEEQFCLERFG--------ARPVDYVESLGWLGDDVWFAHGVHL
MAB_2927c|M.abscessus_ATCC_199 HLAETKDESVYCAERFG--------CSPLDYMEELGWLGPDVWFAHGVHF
Mb2078c|M.bovis_AF2122/97 PYADAPDCIGTCHLDVDGIEAHVRACTKAEVTAGFHVIGDAAVSAAVAAF
Rv2052c|M.tuberculosis_H37Rv PYADAPDCIGTCHLDVDGIEAHVRACTKAEVTAGFHVIGDAAVSAAVAAF
Mvan_3147|M.vanbaalenii_PYR-1 HLAEVREEVTTARHRWG--------HRTVEHSLRAGLFERPLIAGHGVWL
TH_3859|M.thermoresistible__bu --VTMHTNCVWTRPEFH----------DVELYHRAGLLRAGQIHSHANRC
Mflv_2466|M.gilvum_PYR-GCK --GVMSHSTAPGAQQYS----------DEEFAAIADEAHRAGVRVAAHAV
:
MMAR_2844|M.marinum_M S----KGDIAKLAATGTGVAHCPTSNGRFGAGIAPIPELLAAD---VAVG
MUL_2914|M.ulcerans_Agy99 S----KGYIAKLAATGTGVAHCPTSNGRFGAGIAPIPELLAAD---VAVG
MSMEG_1297|M.smegmatis_MC2_155 S----ASDIAKLAQTGTGVAHCPSSNARLGAGTAPIPELLAAG---VPVG
MAB_2927c|M.abscessus_ATCC_199 D----DASIARLARTGTGIAHCPTSNGRLGAGIARVRELLAAG---VPVG
Mb2078c|M.bovis_AF2122/97 ERVVADLGVVAVARCGHRLEHVEMVTADQAAKLGAWGVIASVQPNFDELW
Rv2052c|M.tuberculosis_H37Rv ERVVADLGVVAVARCGHRLEHVEMVTADQAAKLGAWGVIASVQPNFDELW
Mvan_3147|M.vanbaalenii_PYR-1 T----EADIATFARHGAAIAHNPVANMILASGVCPVPRLRAAG---VPVG
TH_3859|M.thermoresistible__bu S----DHELALLRDAGCAVSSTPDTELQMGCGRPVFRRALATG---VTAG
Mflv_2466|M.gilvum_PYR-GCK G----DSAIRACIRAGIDCIEHGFLATDETLQMMVDHGTFLVSTTYLTEA
: * .
MMAR_2844|M.marinum_M LGVDGAG-------AEHRGLANEMRQAALAARFR-------LGPQALDAR
MUL_2914|M.ulcerans_Agy99 LGVDGAG-------AEHRGLANEMRQAALAARFR-------LGPQALDAR
MSMEG_1297|M.smegmatis_MC2_155 MGVDGVAS------NEHGGLGGELRQALLMARNR-------LGPTAITAR
MAB_2927c|M.abscessus_ATCC_199 LGVDGAAS------NESGRLLEEAHQALLLARAV-------GGPTALSTR
Mb2078c|M.bovis_AF2122/97 GGGDGMYA------RRLGAQRGSELNPLALLASQ-------GVPLALGSD
Rv2052c|M.tuberculosis_H37Rv GGGDGMYA------RRLGAQRGSELNPLALLASQ-------GVPLALGSD
Mvan_3147|M.vanbaalenii_PYR-1 IGTDGAAS------NDSQDMLQAVKAAALLQKVHH------LDALVVDAL
TH_3859|M.thermoresistible__bu IGIDIVSNNSGDMFTAMRVLMQHERGDALQPTLEESGLTAVAEPLPVTTR
Mflv_2466|M.gilvum_PYR-GCK MAVDRIAP------------ELRKKAEVVFPQAQA------MLPKAIAAG
. * . : :
MMAR_2844|M.marinum_M EALWMATVGGARCLGR-DQDLGSLEVGKLADIALWQLDGLGHSDVEDP-V
MUL_2914|M.ulcerans_Agy99 EALWMATVGGARCLGR-DQDLGSLEVGKLADIALWQLDGLGHSDVEDP-V
MSMEG_1297|M.smegmatis_MC2_155 QVLQAGTIGGARCLGR-DRELGSLEPGKLADMALWRVDGLGHADIDDP-V
MAB_2927c|M.abscessus_ATCC_199 TALELATLGGARLLGR-SDEIGSIEVGKCADLVLWDLSTLGHSGIEDP-V
Mb2078c|M.bovis_AF2122/97 APVTGFDPWASVRAAV-NHRTPGSGVSARAAFAAATRGGWRAGGVRDGRI
Rv2052c|M.tuberculosis_H37Rv APVTGFDPWASVRAAV-NHRTPGSGVSARAAFAAATRGGWRAGGVRDGRI
Mvan_3147|M.vanbaalenii_PYR-1 DVLTMATIDGARALGL-DHLVGSLEPGKRADIVLLQDT-VDVAVLHDP-V
TH_3859|M.thermoresistible__bu QILHAATLAGARALGL-ESVCGSIDVGKSADLLLLRHDRLHMRPVIDD-I
Mflv_2466|M.gilvum_PYR-GCK VRIACGTDAPAVPHGQNAKELCALVSRGMTPMQALRAATITSAELIDA--
: : . . : : : *
MMAR_2844|M.marinum_M WALIYGPPAP-LRLLLVGGNTVVED----GELRTADTETLATDAKNAAVT
MUL_2914|M.ulcerans_Agy99 WALIYGPPAP-LRLLLVGGNTVVED----GELRTADTETLATDAKNAAVT
MSMEG_1297|M.smegmatis_MC2_155 CALVFGPSAP-LRLLLVNGVPVVAD----DELRTADTATLAGDARDAART
MAB_2927c|M.abscessus_ATCC_199 AAVILGEVPP-IRRSWVGGRPIVAD----GQMLTVDTERIAVAVRAAHHG
Mb2078c|M.bovis_AF2122/97 GTLVPGAPAS-YAIWDAGDFDVDAPRDAVQRWSTDPRSRVPALPRLGPTD
Rv2052c|M.tuberculosis_H37Rv GTLVPGAPAS-YAIWDAGDFDVDAPRDAVQRWSTDPRSRVPALPRLGPTD
Mvan_3147|M.vanbaalenii_PYR-1 AQLVYGASPRSVRDVWVDGVQVVAD----HRCTTVDEATQIARCRPLADR
TH_3859|M.thermoresistible__bu DSIVLQATTRDIDRVLVAGRTVVQD----GRLPAAVERRGVAAIEAAHSR
Mflv_2466|M.gilvum_PYR-GCK EDELGRLAPGYLADIIAVDGDVSAD------IATTLDVRFVMKDGVVHKT
: . . . : :
MMAR_2844|M.marinum_M LRERG-----------------------------------
MUL_2914|M.ulcerans_Agy99 LRERG-----------------------------------
MSMEG_1297|M.smegmatis_MC2_155 LRARAGT---------------------------------
MAB_2927c|M.abscessus_ATCC_199 LMNRER----------------------------------
Mb2078c|M.bovis_AF2122/97 ALPRCRQTVHRGAVIYG-----------------------
Rv2052c|M.tuberculosis_H37Rv ALPRCRQTVHRGAVIYG-----------------------
Mvan_3147|M.vanbaalenii_PYR-1 VGVKAGLVATGHSVVTG-----------------------
TH_3859|M.thermoresistible__bu LAERVAAVGGWKLAVPQGLMDQLGVTFHDNVANTPAQANS
Mflv_2466|M.gilvum_PYR-GCK VDVAQDASTSTV----------------------------