For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PAAMRPYVTAGVALVGASVISVTPIAPQVIAERASEQYVTLTAAAGALCEAESTSPLCTDPGQLDSAVTT SAVFGESSLAYIPGNLINALLSIPAWEIQAMDRLADAMIGTGSWQVWGPTNVFGFDQWDPPKLKAFVDML VPFKPFSSVLGEQMSVWAQANLPMNSGCAGTPGACPDMSMLLASMFKVPMSQLYEGYTFPEAGEQGSTNP FDGSIVPWAGQTVKLEPWGPFTSSWEWLTSPPEPVATVPLSDFIRVPLKLAKSLFDAFNPFVQNSGIFNP KNGLVAAVAKALAPLFCKNCDLDNLYDNPWLYDNYDPHPPIPEAEPESATEGSEAAAEVAEAAVDEPVQE SAEGTEETAPADPTEAAVASLLEKFQSAGAEDEDADTEEEPAEEPAEEPAEEPADDVEDDSEAEAEADEA EADEASGSGKHHLGEGDEENSVKSIQDKVGADKESDSGSDSGSGGDGADA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3114 | - | - | 100% (471) | hypothetical protein Mvan_3114 |
| M. vanbaalenii PYR-1 | Mvan_3110 | - | 5e-59 | 32.79% (491) | hypothetical protein Mvan_3110 |
| M. vanbaalenii PYR-1 | Mvan_2962 | - | 2e-39 | 29.73% (518) | hypothetical protein Mvan_2962 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2471c | rne | 4e-05 | 32.08% (106) | ribonuclease E |
| M. gilvum PYR-GCK | Mflv_3378 | - | 3e-48 | 30.63% (480) | hypothetical protein Mflv_3378 |
| M. tuberculosis H37Rv | Rv2444c | rne | 4e-05 | 32.08% (106) | ribonuclease E |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1607 | - | 2e-05 | 29.45% (163) | ribonuclease E |
| M. marinum M | MMAR_2416 | lgt | 3e-12 | 36.00% (150) | prolipoprotein diacylglyceryl transferases Lgt |
| M. avium 104 | MAV_3172 | - | 4e-12 | 35.66% (129) | prolipoprotein diacylglyceryl transferase |
| M. smegmatis MC2 155 | MSMEG_5468 | - | 1e-06 | 33.88% (121) | hypothetical protein MSMEG_5468 |
| M. thermoresistible (build 8) | TH_4350 | - | 2e-07 | 59.09% (44) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3715 | rne | 9e-07 | 25.00% (152) | ribonuclease E Rne |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2471c|M.bovis_AF2122/97 ---------MIDGAP-------PSDPP-EPSQHEELPDRLRVHSLARTLG
Rv2444c|M.tuberculosis_H37Rv ---------MIDGAP-------PSDPP-EPSQHEELPDRLRVHSLARTLG
MUL_3715|M.ulcerans_Agy99 ---------MVDGAP-------SSDPENEPTQREDLPDRLRVHSLARTLG
MAB_1607|M.abscessus_ATCC_1997 MADYELPEDLHTSAPEGEHAALTPDTPPAPAEQGELPEKLRVHSLARVLG
MMAR_2416|M.marinum_M -----------------------------------------MTATVLAYF
MAV_3172|M.avium_104 ------------------------------------------MTKLLAYF
Mvan_3114|M.vanbaalenii_PYR-1 ----------------------------------MPAAMRPYVTAGVALV
Mflv_3378|M.gilvum_PYR-GCK ----------------------------------MHSALRPYVTTGLALV
TH_4350|M.thermoresistible__bu ----------------------------------MLASIRPYATAGVALV
MSMEG_5468|M.smegmatis_MC2_155 -----------------------------------------MPSIPQSLL
:
Mb2471c|M.bovis_AF2122/97 TTSRRVLDALTALDGRVRSAHSTVDRVDAVRVRDLLATHLETAG------
Rv2444c|M.tuberculosis_H37Rv TTSRRVLDALTALDGRVRSAHSTVDRVDAVRVRDLLATHLETAG------
MUL_3715|M.ulcerans_Agy99 TSSRRVLDALSALDGRIRSAHSSVDRVDAVRVRDLLAEQPAEEGQAEED-
MAB_1607|M.abscessus_ATCC_1997 TSTRRVLDALSNLDGRARSPHSNVDKQDAAKVREVLANEAEAAPVVAETP
MMAR_2416|M.marinum_M PSPPRGVWHLGPLPIRAYAFFIIIGIVMGLMIGDRRFAARGGER------
MAV_3172|M.avium_104 PSPPQGVWHLGPVPIRAYALFIIAGIVAALLIGDRRWEARGGER------
Mvan_3114|M.vanbaalenii_PYR-1 GASVISVTPIAP------QVIAERASEQYVTLTA----------------
Mflv_3378|M.gilvum_PYR-GCK GTSVIALAPIAPPAPAFGGATVAKQVTQDVTLSARVVTLNPTPDALEMGE
TH_4350|M.thermoresistible__bu GAGVIAVTPVAPPPADIQVSRQAVALSAISNPGDP---------------
MSMEG_5468|M.smegmatis_MC2_155 WISLVVLWLFVLVPMLISKRESVRRTSDVALATRVLNS------------
: .
Mb2471c|M.bovis_AF2122/97 -----------VLAASVHAPEASEEPESRLMLETQETR----------NA
Rv2444c|M.tuberculosis_H37Rv -----------VLAASVHAPEASEEPESRLMLETQETR----------NA
MUL_3715|M.ulcerans_Agy99 -----QQAPDAVAAEVPDAPGEPAEPESRLMLETQETVQVV-------ET
MAB_1607|M.abscessus_ATCC_1997 APVAAEEAPAVVTGDSADSAEDPDNPPTTPILIAEATVIEAAAVPVPAAA
MMAR_2416|M.marinum_M --------------------------------------------------
MAV_3172|M.avium_104 --------------------------------------------------
Mvan_3114|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3378|M.gilvum_PYR-GCK Q----------------------------------------------LQG
TH_4350|M.thermoresistible__bu --------------------------------------------------
MSMEG_5468|M.smegmatis_MC2_155 --------------------------------------------------
Mb2471c|M.bovis_AF2122/97 DVERPHYMPLFVAPQP-----IPEPLADDEDVDDGPDY-VADDSDADDEG
Rv2444c|M.tuberculosis_H37Rv DVERPHYMPLFVAPQP-----IPEPLADDEDVDDGPDY-VADDSDADDEG
MUL_3715|M.ulcerans_Agy99 WVERPHYMPLFVAPQP-----ISEPVAGDDADDE------SGDEGDDDEE
MAB_1607|M.abscessus_ATCC_1997 APTAYDYGPLFVAPQAPEPQERPAPVRTEKAEDVDEDAGETDDSDADGEG
MMAR_2416|M.marinum_M --GVIYDIALWMVPFG-----------------------------LIGGR
MAV_3172|M.avium_104 --GVIYDIALWTVPFG-----------------------------LVGGR
Mvan_3114|M.vanbaalenii_PYR-1 ----AAGALCEAESTSP---------------------------LCTDPG
Mflv_3378|M.gilvum_PYR-GCK SICGGNGTPCYEVEYAP---------------------------IWTGPG
TH_4350|M.thermoresistible__bu ---VVAYGELIANTIGS---------------------------LQGLGG
MSMEG_5468|M.smegmatis_MC2_155 ---GRNAQRLRRGPAAG---------------------------------
Mb2471c|M.bovis_AF2122/97 QLDRPANRRRRRGRRGRGRGRGEQGGSDGDPVDQQSEPRAQQFTSADAAE
Rv2444c|M.tuberculosis_H37Rv QLDRPANRRRRRGRRGRGRGRGEQGGSDGDPVDQQSEPRAQQFTSADAAE
MUL_3715|M.ulcerans_Agy99 QADRPGNRRRRRGRRGRGRGRGEQGANDGQDQPGDDGDEAPQKAGGNSTS
MAB_1607|M.abscessus_ATCC_1997 DGDRP-ARRRRRGRRGRGRGRGEQGGGEGSD-DSGDDAAAEGGEAAEGDD
MMAR_2416|M.marinum_M LYHLSTDWQTYFGEGGAGLG------------------------------
MAV_3172|M.avium_104 LYHLATDWRTYWGPGGAGFG------------------------------
Mvan_3114|M.vanbaalenii_PYR-1 QLDSAVTTS-----------------------------------------
Mflv_3378|M.gilvum_PYR-GCK YFGLGVEALREALTGNPGEETTIFAFSEGAVVASQWLEKHLEDPEAYPAP
TH_4350|M.thermoresistible__bu QFAADPAPVLVKILQN----------------------------------
MSMEG_5468|M.smegmatis_MC2_155 -HNSDPHWR-----------------------------------------
Mb2471c|M.bovis_AF2122/97 TDDGDDRDSEDTEAGDNGEDENGSLEAGNRRRRRRRRRKSASGDDNDAAL
Rv2444c|M.tuberculosis_H37Rv TDDGDDRDSEDTEAGDNGEDENGSLEAGNRRRRRRRRRKSASGDDNDAAL
MUL_3715|M.ulcerans_Agy99 SDDSEAQDGADSEESDNGDDDNGSADGASRRRRRRRRRKSGAGDDGD---
MAB_1607|M.abscessus_ATCC_1997 AADGTGDDSPAPDGDESNAEDGDTPEGASRRRRRRRRRKAGSGDDGD---
MMAR_2416|M.marinum_M ---------AALRIWDGGLGIWGAVTLGTVGAWIGCRRRGIP-------L
MAV_3172|M.avium_104 ---------AAVRIWDGGLGIWGAVALGAVGAWIGCRRHGIP-------L
Mvan_3114|M.vanbaalenii_PYR-1 -----AVFG-----------------------------------------
Mflv_3378|M.gilvum_PYR-GCK ENLTFVVIGNPARKYGGSGTIWGRQWPTSPYQVIDVAQQYDPTVDMPVNN
TH_4350|M.thermoresistible__bu --------------------------------------------------
MSMEG_5468|M.smegmatis_MC2_155 --------------------------------------------------
Mb2471c|M.bovis_AF2122/97 EGPLPDDPPNTVVHERVPRAGDKAGNSQDGG-SGSTEIKGIDGSTRLEAK
Rv2444c|M.tuberculosis_H37Rv EGPLPDDPPNTVVHERVPRAGDKAGNSQDGG-SGSTEIKGIDGSTRLEAK
MUL_3715|M.ulcerans_Agy99 EGPAPDDPPNTVVHERAPRSGDKSGNSDSGDDSGGNEIKGIDGSTRLEAK
MAB_1607|M.abscessus_ATCC_1997 -GPSDDDPPNTVVHERKPRAE------------RGDEIQGISGSTRLEAK
MMAR_2416|M.marinum_M PAFLDAVAPGVVMGQAIGRLGN----------YFNQELYGRETTVPWGLE
MAV_3172|M.avium_104 PAFADALAPGIILAQAIGRLGN----------YFNQELYGRETTLPWGLE
Mvan_3114|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3378|M.gilvum_PYR-GCK LNVLATLNATMGFFTNHLGRGYSDVDIDDPA-NSRWEEDGIEYVFVPAKT
TH_4350|M.thermoresistible__bu --------------------------------------------------
MSMEG_5468|M.smegmatis_MC2_155 --------------------------------------------------
Mb2471c|M.bovis_AF2122/97 RQRRRDGRDAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEPPLPGTR
Rv2444c|M.tuberculosis_H37Rv RQRRRDGRDAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEPPLPGTR
MUL_3715|M.ulcerans_Agy99 RQRRRDGRDAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEPPHPGSR
MAB_1607|M.abscessus_ATCC_1997 RQRRRDGRDAGRRRPPILTEAEFLARREAVDRVMVVRDKTRSEPPHEGAR
MMAR_2416|M.marinum_M IFYRRD--------PSGFVDVHSLDGVSTGQVAVVVQPTFLYELIWNLLV
MAV_3172|M.avium_104 IFYRRD--------PSGYIDPHSLDGVSTGQVALVVQPTFLYELLWNLLI
Mvan_3114|M.vanbaalenii_PYR-1 ---------------------------------------------ESSLA
Mflv_3378|M.gilvum_PYR-GCK LPLVEPLRWVGLGQLADELTPGLQYLIEQGYNRDDRITGTTIDAPEKSWS
TH_4350|M.thermoresistible__bu -------------------------------------------------Q
MSMEG_5468|M.smegmatis_MC2_155 --------------------------------------------------
Mb2471c|M.bovis_AF2122/97 YTQIAVLEDGIVVEH--FVTSAASASLVGNIYLGIVQNVLPSMEAAFVDI
Rv2444c|M.tuberculosis_H37Rv YTQIAVLEDGIVVEH--FVTSAASASLVGNIYLGIVQNVLPSMEAAFVDI
MUL_3715|M.ulcerans_Agy99 YTQIAVLEDGIVVEH--FVTSAASASLVGNIYLGIVQNVLPSMEAAFVDI
MAB_1607|M.abscessus_ATCC_1997 YTQIAVLEDGVLVEH--FVTSAASASLVGNIYLGVVQNVLPSMEAAFVDI
MMAR_2416|M.marinum_M FAALIYLDRRFTIGHGRLFASYVALYCVGRFCVELLRDDTATHIAG-IRI
MAV_3172|M.avium_104 FVALLYADRRLTLGHGRLFALYVAGYCVGRFCVELLRDDTATHIAG-IRI
Mvan_3114|M.vanbaalenii_PYR-1 YIPGNLINALLSIPAWEIQAMDRLADAMIGTGSWQVWGPTNVFGFDQWDP
Mflv_3378|M.gilvum_PYR-GCK YAPINFLEAIANIPYYSVAGTNRFANAMRASGSWWVYTPTNVLGWDPANP
TH_4350|M.thermoresistible__bu IANGQLIGSALDEALGFLLQGVEALPGALEEAFALLTQGDLKGAVDAFMM
MSMEG_5468|M.smegmatis_MC2_155 -PTPDHLDDEFEAELEETEPSRPPKRAVVVAAAATEPAEPDYLDVDIVEE
Mb2471c|M.bovis_AF2122/97 GRGRNGVLYAGEVNWDAAGLGGADRKIEQALKPGDYVVVQVSKDPVGHKG
Rv2444c|M.tuberculosis_H37Rv GRGRNGVLYAGEVNWDAAGLGGADRKIEQALKPGDYVVVQVSKDPVGHKG
MUL_3715|M.ulcerans_Agy99 GRGRNGVLYAGEVNWDAAGLGGADRKIEQALKPGDYIVVQVSKDPVGHKG
MAB_1607|M.abscessus_ATCC_1997 GRGRNGVLYAGEVNWDAAGLGGSNRKIEQALKSGDYVLVQVSKDPVGHKG
MMAR_2416|M.marinum_M NSFTSTFVFIGAVVYIILAPKGRE---DPASVRGTAAAAEEVPEPE----
MAV_3172|M.avium_104 NSFTSTFVFIGAVVYLMAAPKGRE---DPESLRGNQYVEEEPAEPE----
Mvan_3114|M.vanbaalenii_PYR-1 PKLKAFVDMLVPFKPFSSVLGEQMSVWAQANLPMNSGCAGTPGACPDMSM
Mflv_3378|M.gilvum_PYR-GCK EMTRAFVDFLVAIPSISTPMGMTADWWARANLPMNEGCTGFP-PCDNPAG
TH_4350|M.thermoresistible__bu GIIPAALGMIVPLVAGSMIITNTADNFARAVSAVLDVDAMLPTLLGFAGP
MSMEG_5468|M.smegmatis_MC2_155 DSGALPLGATHAPEIEDVEVVEEVEPADDAQTDQLSLDLDEAGDEAGDEA
.
Mb2471c|M.bovis_AF2122/97 ARLTTQVSLAGRFLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAG
Rv2444c|M.tuberculosis_H37Rv ARLTTQVSLAGRFLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAG
MUL_3715|M.ulcerans_Agy99 ARLTTQVSLAGRYLVYVAGASSTGISRKLPDTERQRLKEILREVVPSDAG
MAB_1607|M.abscessus_ATCC_1997 ARLTTQISLAGRYLVYVPGASSTGISRKLPDTERQRLKEILRDIVPADAG
MMAR_2416|M.marinum_M --PAGEVATAAAPAGDTEGDEPTGLAETAKAAEVAEPETVGSAVAGDEST
MAV_3172|M.avium_104 --PATVAATTEAAT--------EGVAAPADG-------------------
Mvan_3114|M.vanbaalenii_PYR-1 LLASMFKVPMSQLYEG----YTFPEAGEQ----------GSTNPFDGSIV
Mflv_3378|M.gilvum_PYR-GCK ITDQMFKVQLWDFFAPGGFTFTDPITPEYNPISDTEAFWGQELGLTGDKV
TH_4350|M.thermoresistible__bu VLSAVDGFVT----SG----------------------------------
MSMEG_5468|M.smegmatis_MC2_155 DEAVEE--PE----------------------------------------
Mb2471c|M.bovis_AF2122/97 VIIRTASEGVKEDDIRADVARLRERWEQIEAKAQETKEKAAGAAVALYEE
Rv2444c|M.tuberculosis_H37Rv VIIRTASEGVKEDDIRADVARLRERWEQIEAKAQETKEKAAGAAVALYEE
MUL_3715|M.ulcerans_Agy99 VIIRTASEGVKEDDIRADVTRLQERWNQIEAKAVEIKQKAAGAAVALYEE
MAB_1607|M.abscessus_ATCC_1997 VIIRTASEGVREEDIRADVQRLQEQWQGIEQSATDLTSKASGAAVALYEE
MMAR_2416|M.marinum_M ADTEASDAVESEVGEAAEAEAPEAEAEEAEVGEVEVAEAVEGEVEEAEEA
MAV_3172|M.avium_104 -------------AEAAGADATAQRPEESAEPDVEKPESEETEAEAAEEP
Mvan_3114|M.vanbaalenii_PYR-1 PWAGQTVKLEPWGPFTSSWEWLTSPPEPVATVPLSDFIRVPLKLAKSLFD
Mflv_3378|M.gilvum_PYR-GCK EWYGETVHPEPFGETKGFLDFLISTPEGIKTPTLQDQLNAFRNLADGLTT
TH_4350|M.thermoresistible__bu ---------------QAVLDGVLAGDPIAVLNAVASTPAVLIDAVLNGSG
MSMEG_5468|M.smegmatis_MC2_155 ----------------PVAEVAEEPEEADEPAAPVDEDDTADDQSDLAAH
Mb2471c|M.bovis_AF2122/97 PDVLVKVIRDLFNEDFVGLIVSGDEAWNTINEYVNSVAPELVSKLTKYES
Rv2444c|M.tuberculosis_H37Rv PDVLVKVIRDLFNEDFVGLIVSGDEAWNTINEYVNSVAPELVSKLTKYES
MUL_3715|M.ulcerans_Agy99 PDVLVKVIRDLFNEDFAGLVVSGDDAWDTINEYVSSVAPDLVSKLSKYEP
MAB_1607|M.abscessus_ATCC_1997 PDVLVKVVRDLFNEDFSKLIIEGDAAWDTIDDYVKTVAPDLLSRIERYES
MMAR_2416|M.marinum_M EPGEVEVAEAVEGEVEAAAEAEEAEEAEEAEEAEEAEEAEPG--------
MAV_3172|M.avium_104 E----------------------SEETEAAEEPGEPEAEEP---------
Mvan_3114|M.vanbaalenii_PYR-1 AFNPFVQNSGIFNPKNGLVAAVAKALAPLFCKNCDLDN------------
Mflv_3378|M.gilvum_PYR-GCK TWNPFVPKSYVWNPDMTPFAYLARPLAKILCPTCNAVDPFMPEDW-----
TH_4350|M.thermoresistible__bu ALLGFLPLPGLLTPATAPIGGPIATLLGIRNAIADALQP-----------
MSMEG_5468|M.smegmatis_MC2_155 EYEYVADSSGLEEPETEPETAEDEAPAAAMSSSR----------------
Mb2471c|M.bovis_AF2122/97 ADGPDGQSAPDVFTVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVID
Rv2444c|M.tuberculosis_H37Rv ADGPDGQSAPDVFTVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVID
MUL_3715|M.ulcerans_Agy99 AVGSEGQVGPDVFAVHRIDEHLAKAMDRKVWLPSGGTLVIDRTEAMTVVD
MAB_1607|M.abscessus_ATCC_1997 GEG------PDVFAVHRIDEQLAKALDRKVWLPSGGTLVIDRTEAMTVVD
MMAR_2416|M.marinum_M ----------EIEVAEAVEGEVEAAAEAEEAEVGEVEAVDEAAEAEAPEV
MAV_3172|M.avium_104 ----------------------------------------EEPEAEEPEE
Mvan_3114|M.vanbaalenii_PYR-1 --------------------LYDNPWLYDNYDPHPPIPEAEPESATEGSE
Mflv_3378|M.gilvum_PYR-GCK -----------KVGLDVYPGAYIPPSVKDQYDPETGKYIGDPVDGLTDAE
TH_4350|M.thermoresistible__bu ---------------------------------------VEQIAAASAAA
MSMEG_5468|M.smegmatis_MC2_155 ---------------------------------------QRRMESKTAAQ
.
Mb2471c|M.bovis_AF2122/97 VNTGKFTGAGGNLEQTVTKNNLEAAEEIVRQLR-LRDIGGIVVIDFIDMV
Rv2444c|M.tuberculosis_H37Rv VNTGKFTGAGGNLEQTVTKNNLEAAEEIVRQLR-LRDIGGIVVIDFIDMV
MUL_3715|M.ulcerans_Agy99 VNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLR-LRDIGGIVVIDFIDMV
MAB_1607|M.abscessus_ATCC_1997 VNTGKFTGAGGNLEETVTRNNLEAAEEIVRQLR-LRDVGGIVVIDFIDMV
MMAR_2416|M.marinum_M GEIEAAEAVEGEVEVAAEAEEAEAGEDEPKEAEEVAEAEGSEAEDKTVQA
MAV_3172|M.avium_104 ----------------PETEEPEADSDE----------------------
Mvan_3114|M.vanbaalenii_PYR-1 AAAEVAEAAVDEPVQESAEGTEETAP------------------------
Mflv_3378|M.gilvum_PYR-GCK IAEWNEKAGLNDIVDETTDGTEETEESGDVSED---------PADADTSL
TH_4350|M.thermoresistible__bu PMAAKAEVKAEEEVDAVAAVTSVPGE------------------------
MSMEG_5468|M.smegmatis_MC2_155 VSERKYRFRKRVLALFALILVASAAAAFLVTPT-----------------
.
Mb2471c|M.bovis_AF2122/97 LESNRDLVLRRLTESLARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFS
Rv2444c|M.tuberculosis_H37Rv LESNRDLVLRRLTESLARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFS
MUL_3715|M.ulcerans_Agy99 LESNRDLVLRRLTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFS
MAB_1607|M.abscessus_ATCC_1997 LESNRDLVLRRLTEALGRDRTRHQVSEVTSLGLVQLTRKKLGTGLIEAFS
MMAR_2416|M.marinum_M IDGGQTGVDDAGEADAEPDDDSTAAEPEVVVEQADIEEIEPQEPEAEAVA
MAV_3172|M.avium_104 ----------------EPE-------------------------------
Mvan_3114|M.vanbaalenii_PYR-1 ----------------------ADPTEAAVASLLEKFQSAGAEDEDADTE
Mflv_3378|M.gilvum_PYR-GCK LSARSMATVDESSEDTGASDKKTDVISAAVQDLVDTFDKTPAAEDTEQGA
TH_4350|M.thermoresistible__bu --------------------------NFRTVNLTTELSTAVENPVAGEPK
MSMEG_5468|M.smegmatis_MC2_155 --------------------------AWWVCGTTATLTVLYLAYLRRQTR
Mb2471c|M.bovis_AF2122/97 TSCPNCSGRGILLHADPVD---SAAATGRKSEPGARRGKRSKKSRSEESS
Rv2444c|M.tuberculosis_H37Rv TSCPNCSGRGILLHADPVD---SAAATGRKSEPGARRGKRSKKSRSEESS
MUL_3715|M.ulcerans_Agy99 TSCPHCSGRGILLHADPVD---SAPTTGRKADSGGRRNRRSKKNRAEEPS
MAB_1607|M.abscessus_ATCC_1997 STCTHCAGRGIVLHVDPVDNASNASSPAKKAETG-RRAKRSRKGK----T
MMAR_2416|M.marinum_M AAEATDADEGDGEPAEPASDDLDAVAAEDADVDVDAT-------------
MAV_3172|M.avium_104 --------------------------------------------------
Mvan_3114|M.vanbaalenii_PYR-1 EEPA--EEPAEEPAEEPAD-------------------------------
Mflv_3378|M.gilvum_PYR-GCK ETPAGSEEPTQPQDETPAA-------------------------------
TH_4350|M.thermoresistible__bu KSAAVDGVPTTVATEEATTG------------------------------
MSMEG_5468|M.smegmatis_MC2_155 IEEQLRRRRAQRLRRSRLG-------------------------------
Mb2471c|M.bovis_AF2122/97 DRSMVAKVPVHAPGEHPMFKAMAAGLSSLAGRGD---EESGE-PAAELAE
Rv2444c|M.tuberculosis_H37Rv DRSMVAKVPVHAPGEHPMFKAMAAGLSSLAGRGD---EESGE-PAAELAE
MUL_3715|M.ulcerans_Agy99 EKEAVAKVPTYAPGEHPMFKAMAASSSSEAEHGDGEVEESGEELTAAVDD
MAB_1607|M.abscessus_ATCC_1997 DDVVVARTPSHPQGEHPMFKAMAAANGHHEDDED-----------ADVNE
MMAR_2416|M.marinum_M --------------------------------------------------
MAV_3172|M.avium_104 --------------------------------------------------
Mvan_3114|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3378|M.gilvum_PYR-GCK --------------------------------------------------
TH_4350|M.thermoresistible__bu --------------------------------------------------
MSMEG_5468|M.smegmatis_MC2_155 --------------------------------------------------
Mb2471c|M.bovis_AF2122/97 QAGDQPPTDLDDTAQA--------------DFEDTEDTDEDED-------
Rv2444c|M.tuberculosis_H37Rv QAGDQPPTDLDDTAQA--------------DFEDTEDTDEDED-------
MUL_3715|M.ulcerans_Agy99 QTAVQVALDLGETEESEETDGTDETDDFDDDSDDSDDSDEDDDTDETNDT
MAB_1607|M.abscessus_ATCC_1997 DALDDD------------------------ALEEVEEVEEIVET------
MMAR_2416|M.marinum_M -------------------------------ATEAEESGDESPE------
MAV_3172|M.avium_104 -----------------------------------EESGEAPEQ------
Mvan_3114|M.vanbaalenii_PYR-1 --------------------------------DVEDDS------------
Mflv_3378|M.gilvum_PYR-GCK --------------------------------DADDDAGVDAEP-----V
TH_4350|M.thermoresistible__bu --------------------------------------------------
MSMEG_5468|M.smegmatis_MC2_155 --------------------------------------------------
Mb2471c|M.bovis_AF2122/97 ELDADEDLEDLDDEDLDEDLDVEDSDSDDEDSDEDAADADVDEEDAAG--
Rv2444c|M.tuberculosis_H37Rv ELDADEDLEDLDDEDLDEDLDVEDSDSDDEDSDEDAADADVDEEDAAG--
MUL_3715|M.ulcerans_Agy99 DVDADEDEDTDDDSDEDEDTEDDDELDDDLDDELDDDDSDSDDEDSESEL
MAB_1607|M.abscessus_ATCC_1997 -IQSAETPDNVPDQDEPE--HEPASAGSNAASEPWAEGAPEAAATEPG--
MMAR_2416|M.marinum_M --PAADSEEPEADESAPEDSAEDTSSGESDTQSELEQSQTIEQGSDQTSA
MAV_3172|M.avium_104 --PVAE--EPEPAPQQPE--------------------------------
Mvan_3114|M.vanbaalenii_PYR-1 ----------EAEAEADEAEADEASGSGKHHLGEGDEENSVKSIQDKVGA
Mflv_3378|M.gilvum_PYR-GCK TTPRKPSSTTKSDVDASESADADATTSGTAGTSESSESEKSDTSSDSSAS
TH_4350|M.thermoresistible__bu ---ATESLDPAAATEGDDGLEDDSAKNANGGTDLSDGNKATPATTAGDTS
MSMEG_5468|M.smegmatis_MC2_155 --------VENTDDRKLDVVPARLRRPGAVVLDIDDEDPIFEHLEYTTFA
:
Mb2471c|M.bovis_AF2122/97 LDGSPGEVDVPGVTELAPTRPRRR-VAGRPAGPPIRLD
Rv2444c|M.tuberculosis_H37Rv LDGSPGEVDVPGVTELAPTRPRRR-VAGRPAGPPIRLD
MUL_3715|M.ulcerans_Agy99 TEPAAGRPAALEVTTIAERPRRRR-AAGRPAGPPIHLG
MAB_1607|M.abscessus_ATCC_1997 TAEPEAPAATPEPAAAAPTRPRRRRSAARAAGPPVEH-
MMAR_2416|M.marinum_M GDGEGPPPSAAVDGDTGPTRQGWRGRLRNRMRRSGR--
MAV_3172|M.avium_104 ------------------TKRRWGARLRDRL--SGR--
Mvan_3114|M.vanbaalenii_PYR-1 DK-ESDSGSDSGSGGDGADA------------------
Mflv_3378|M.gilvum_PYR-GCK DSSASDSASSSDSSGSGAGSSGSGGSAGSGGGSDD---
TH_4350|M.thermoresistible__bu ADSGSNKAGQSTLRAGVKKATAKASAASSTGGSDE---
MSMEG_5468|M.smegmatis_MC2_155 REYDLPRASGQ---------------------------