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KFGFRAKTASIIGAAAAATLMAAAPSALAEPTGPGLPEPAPALLSAPTPPPAPDAQPTVPLTPPAPAAPV AAASGDPAAVPPAAPAADAGVPHLASPENLPPGTSATPTQQGRLGYFRELWHAMRTQEVSGSDALLLLTQ RPMSSGPQQAMSPVPPAPAPAP*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_3289 | - | - | 100% (163) | hypothetical protein Mflv_3289 |
M. gilvum PYR-GCK | Mflv_1703 | - | 5e-25 | 45.27% (148) | transglycosylase domain-containing protein |
M. gilvum PYR-GCK | Mflv_0374 | - | 7e-11 | 32.05% (156) | hypothetical protein Mflv_0374 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0891c | rpfA | 2e-11 | 34.04% (141) | resuscitation-promoting factor RpfA |
M. tuberculosis H37Rv | Rv0867c | rpfA | 3e-11 | 34.04% (141) | resuscitation-promoting factor RpfA |
M. leprae Br4923 | MLBr_00568 | - | 3e-08 | 27.12% (177) | hypothetical protein MLBr_00568 |
M. abscessus ATCC 19977 | MAB_0869c | - | 4e-16 | 43.80% (121) | resuscitation-promoting factor RpfA |
M. marinum M | MMAR_4294 | - | 6e-12 | 42.86% (105) | hypothetical protein MMAR_4294 |
M. avium 104 | MAV_0996 | - | 4e-13 | 40.94% (127) | resuscitation-promoting factor RpfA |
M. smegmatis MC2 155 | MSMEG_5700 | - | 6e-28 | 51.45% (138) | secreted protein |
M. thermoresistible (build 8) | TH_3373 | - | 1e-08 | 28.82% (170) | PUTATIVE hypothetical protein Mjls_1192 |
M. ulcerans Agy99 | MUL_1004 | - | 1e-11 | 43.12% (109) | hypothetical protein MUL_1004 |
M. vanbaalenii PYR-1 | Mvan_3011 | - | 8e-48 | 62.35% (170) | hypothetical protein Mvan_3011 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3289|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3011|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0891c|M.bovis_AF2122/97 -------MSGRHRKPTTSN--VSVAKIAFTGAVLGGGGIAMAAQATAATD Rv0867c|M.tuberculosis_H37Rv -------MSGRHRKPTTSN--VSVAKIAFTGAVLGGGGIAMAAQATAATD MAV_0996|M.avium_104 --------------------------------MLGGGAIAMAGQAAAATD MSMEG_5700|M.smegmatis_MC2_155 -------MSGRHRKPTSSSSAKNVAKIAFTGAVLGGGGLGMAGQAMAATD MAB_0869c|M.abscessus_ATCC_199 -------MSGRHSKPSKAS--AKAAKVAVAGAGLVGGGLMMAATANAATD MMAR_4294|M.marinum_M -------------MASTWSLSKGLAAVVVTSAAAFGLCPGAAADPAAPQP MUL_1004|M.ulcerans_Agy99 -------------MASTWSLSKGLAAVVVTSAAAFGLCPAAAADPAAPQP MLBr_00568|M.leprae_Br4923 -------------------------------------------------- TH_3373|M.thermoresistible__bu MADFGRWNPNWNPDDGGQPSLQDIHRSEQFIEALSTGRPVYANDPGEDEL Mflv_3289|M.gilvum_PYR-GCK ---------------------------------------MKFGFRAKTAS Mvan_3011|M.vanbaalenii_PYR-1 ---------------------------------------MKFGFRARIAS Mb0891c|M.bovis_AF2122/97 GEWDQVARCESGGNWSINTGNGYLGGLQFTQSTWAAHGGGEFAPSAQLAS Rv0867c|M.tuberculosis_H37Rv GEWDQVARCESGGNWSINTGNGYLGGLQFTQSTWAAHGGGEFAPSAQLAS MAV_0996|M.avium_104 GEWDQVARCESGGNWGINTGNGYHGGVQFSASTWAAHGGGEYAPSAELAT MSMEG_5700|M.smegmatis_MC2_155 GEWDQVARCESGGNWAINTGNGYHGGLQFSPSTWRAHGGTEFAPAAYMAT MAB_0869c|M.abscessus_ATCC_199 GEWDQVARCESGGNWAINTGNGYQGGLQFSPSTWINSGGGQYAPSAHLAT MMAR_4294|M.marinum_M NPNPQLPGLPALAQLSPIIQQAAGNPEQATQLLMAAAQAFAHNPAAPTES MUL_1004|M.ulcerans_Agy99 NPNPQLPGLPALAQLSPIIQQAAGNPEQATQLLMAAAQAFAHNPAAPTES MLBr_00568|M.leprae_Br4923 ----------------MKVFDRFNTAILVSAGLCG--AALAFSPSAAAAP TH_3373|M.thermoresistible__bu AYLMAGWRDRARNAPMRATITEQDAVAALQRGLPRPRGGAPRPGRRFSLT . Mflv_3289|M.gilvum_PYR-GCK IIGAAAAATLMAAAPSAL-AEPTGPG------------------LPEPAP Mvan_3011|M.vanbaalenii_PYR-1 VAGAAAFATLIAAAPSAS-ADPAAPAPAP---------------LPVPGP Mb0891c|M.bovis_AF2122/97 REQQIAVGERVLATQGRG-AWPVCGRGLSNATPREVLPASAAMDAPLDAA Rv0867c|M.tuberculosis_H37Rv REQQIAVGERVLATQGRG-AWPVCGRGLSNATPREVLPASAAMDAPLDAA MAV_0996|M.avium_104 REQQIAVAERVLATQGRG-AWPVCGGPLSGPTPRDVPAP-----AGLDAP MSMEG_5700|M.smegmatis_MC2_155 KEEQIAVAERVLASQGKG-AWPTCGRGLSGATPRNVVAEPEP--APLDAP MAB_0869c|M.abscessus_ATCC_199 KEQQIAVAEKVLAGQGRG-AWPVCGRGLSGSTPRTAPAANITPAAHHEEQ MMAR_4294|M.marinum_M RNVASSVNQFVQEPVNPAPGSPPLGVPAPAAAPVEVAPPASAPVPHVPAP MUL_1004|M.ulcerans_Agy99 RNVASSVNQFVQEPVNPAPGSPPLGVPAPAAAPVEVAPPASAPVPHVPAP MLBr_00568|M.leprae_Br4923 LSMPTGGPTCIEQMAGLGAVPAAVPAVLPGPVAGAVPSVPVVPSGGFPPV TH_3373|M.thermoresistible__bu VVGSAAAAVICLGGFGALVAGAGPGDPLYGLRTMLFGDVVRDDPVVLAAQ . . . Mflv_3289|M.gilvum_PYR-GCK ALLSAPTPPPAP-------------------------------------- Mvan_3011|M.vanbaalenii_PYR-1 AVPDS-APLPAP-------------------------------------- Mb0891c|M.bovis_AF2122/97 AVNGEPAPLAPP-------------------------------------- Rv0867c|M.tuberculosis_H37Rv AVNGEPAPLAPPPADPAPPVELAANDLPAPLGEPLPAAPADPAPPADLAP MAV_0996|M.avium_104 GVNG--VPQAPP-------------------------------------- MSMEG_5700|M.smegmatis_MC2_155 GVNGELPPPAPVDMLAAPMPAPEG-------------------------- MAB_0869c|M.abscessus_ATCC_199 AAAEPAPAPEPPAEGDEQFVAEAP-------------------------- MMAR_4294|M.marinum_M GAEPGTLAHLPAG------------------------------------- MUL_1004|M.ulcerans_Agy99 GAEPGTLAHLPAG------------------------------------- MLBr_00568|M.leprae_Br4923 VPPGGFPPVVPPG------------------------------------- TH_3373|M.thermoresistible__bu TQLAEVEQLIAQGDWEAAQER----------------------------- . Mflv_3289|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3011|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0891c|M.bovis_AF2122/97 ------------------------------------------PADLAPPA Rv0867c|M.tuberculosis_H37Rv PAPADVAPPVELAVNDLPAPLGEPLPAAPADPAPPADLAPPAPADLAPPA MAV_0996|M.avium_104 -------------------------------------------------- MSMEG_5700|M.smegmatis_MC2_155 --------------------------LPPAPEALPPAPEALPPAPEAPAP MAB_0869c|M.abscessus_ATCC_199 ----------------------------------------EAPAIDEAPA MMAR_4294|M.marinum_M ----------------------------------------IDPAHAAGPA MUL_1004|M.ulcerans_Agy99 ----------------------------------------IDPAHAAGPA MLBr_00568|M.leprae_Br4923 -------------------------------------------------- TH_3373|M.thermoresistible__bu ----------------------------------------LQAVTTTVAT Mflv_3289|M.gilvum_PYR-GCK -------------------DAQPTVPLTPPAPAAPVA-AASGD------- Mvan_3011|M.vanbaalenii_PYR-1 -------------------VAAPMASPVPAPLAAPIAGPASVQ------- Mb0891c|M.bovis_AF2122/97 PADLAPPAPADL-----APPVELAVNDLPAPLGEPLPAAPAELAPPADLA Rv0867c|M.tuberculosis_H37Rv PADLAPPAPADL-----APPVELAVNDLPAPLGEPLPAAPAELAPPADLA MAV_0996|M.avium_104 -ADAPPPA-----------PVQLASFDRPAPPDAPAPDAP---------- MSMEG_5700|M.smegmatis_MC2_155 APEALPPAPEALPP---APEALPPAPEAPAPAPEALPPAPEAPAPVAEAL MAB_0869c|M.abscessus_ATCC_199 PEEAPAPEAQDVDFQSGPAPEEPAPAPEPAPVDEAQAPAPELIAAPAPEA MMAR_4294|M.marinum_M PVAAPAGAPPASAPAPAAAAPASAPGTAPAPAAAPGPAPAAPAPAPAAAA MUL_1004|M.ulcerans_Agy99 PVAAPAGAPPASAPAPAAAAPASAPGTAPAPAAAPGPAPAAPAPAPAAAA MLBr_00568|M.leprae_Br4923 -------------------GFLPVVPPGGFPPVVPPGGFPPVVP------ TH_3373|M.thermoresistible__bu VGDETRKQELVAEWQELSVKVESRNPDATVPPDAPPVTLPVIDPATSTEP . . . Mflv_3289|M.gilvum_PYR-GCK -----------------------------------PAAVPPAAPAADAGV Mvan_3011|M.vanbaalenii_PYR-1 -----------------------------------SLAAGPVEPVAEG-V Mb0891c|M.bovis_AF2122/97 PAS------ADLAPPAPADLAPP-----------APAELAPPAPADLAP- Rv0867c|M.tuberculosis_H37Rv PAS------ADLAPPAPADLAPP-----------APAELAPPAPADLAP- MAV_0996|M.avium_104 -------------PPAPADLPP------------APADLPPAPPADATP- MSMEG_5700|M.smegmatis_MC2_155 PPAPEALPPAPEAPPAPEALPPAPEAQIVDASLQVPADVPPAPPVEPAP- MAB_0869c|M.abscessus_ATCC_199 PVVDEAP--APEEAPAPEAPAADDQVLPYELQ-SGPAPAEPAPAPEPAPA MMAR_4294|M.marinum_M PAP--------APAPAAPPAAPVAA----PAPVPAPAPAAAPAPEAAAPA MUL_1004|M.ulcerans_Agy99 PAP--------APAPAAPPAAPVAAPVAAPAPVPAPAPAAAPAPEAAAPA MLBr_00568|M.leprae_Br4923 -----------------------------------PGVAPAVGPLLAEDS TH_3373|M.thermoresistible__bu TEPG--TPSTEPAEPGEPTEPGDPDMPVDGTEPTSPGTEPTAGPDQPTVP . . . Mflv_3289|M.gilvum_PYR-GCK PHLASPENLPPG-------------------------------------- Mvan_3011|M.vanbaalenii_PYR-1 PHLASPENLPPG-------------------------------------- Mb0891c|M.bovis_AF2122/97 PAAVNEQTAP-----------GDQP-----ATAPGGPVGLATDLELPEPD Rv0867c|M.tuberculosis_H37Rv PAAVNEQTAP-----------GDQP-----ATAPGGPVGLATDLELPEPD MAV_0996|M.avium_104 PAPPADAPAPD----------GDFH-----GFVPAG---------MPD-- MSMEG_5700|M.smegmatis_MC2_155 PAPVDAVAAPENQNWDQAPAPADQPQTW--ALHVGGPLPLDPVLPAPAPA MAB_0869c|M.abscessus_ATCC_199 PAAAPEIPLPAG-----VPDAADIGFAAGKAAFDAGPVASNGIPTSPEAV MMAR_4294|M.marinum_M PAPAPAPAAAPGFGPDAPPTQDFMYPSIGTNCLADGSNIIATALSVAGPA MUL_1004|M.ulcerans_Agy99 PAPAPAPAAAPGFGPDAPPTQDFMYPSIGTNCLADGSNIIATALSVAGPA MLBr_00568|M.leprae_Br4923 AALGSGILAGKG-------------------------------------- TH_3373|M.thermoresistible__bu PTVGPTSEPATSEPAMTAPTTTVPTSAPGSAVRTTTSAPTTATTTSGSTT . Mflv_3289|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3011|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0891c|M.bovis_AF2122/97 PQPADAP---------------------------------------PPGD Rv0867c|M.tuberculosis_H37Rv PQPADAP---------------------------------------PPGD MAV_0996|M.avium_104 -------------------------------------------------- MSMEG_5700|M.smegmatis_MC2_155 PAPAPAPGAPAAVAAPAPDPLAPAPNADVAPTPPEGVPHLASPENLPPGT MAB_0869c|M.abscessus_ATCC_199 AGVVRHLP---------------------------------DPNNLPPGT MMAR_4294|M.marinum_M TIPTPGPG---------------------------------------PGQ MUL_1004|M.ulcerans_Agy99 TIPTPGPG---------------------------------------PGQ MLBr_00568|M.leprae_Br4923 -------------------------------------------------- TH_3373|M.thermoresistible__bu AGPTAGG------------------------------------------- Mflv_3289|M.gilvum_PYR-GCK ---TSATPTQQGRLGYFRELWHAMRTQEVSGSDALLLLTQRPMSS----- Mvan_3011|M.vanbaalenii_PYR-1 ---TSTTPTQQSRLGYLRDLWHAMQTQEVSGSNALLLLTQRPLSS----- Mb0891c|M.bovis_AF2122/97 VTEAPAETPQVSNIAYTKKLWQAIRAQDVCGNDALDSLAQ---------- Rv0867c|M.tuberculosis_H37Rv VTEAPAETPQVSNIAYTKKLWQAIRAQDVCGNDALDSLAQ---------- MAV_0996|M.avium_104 ---------HVSEAGYTQRLWEAIRAQDVQGNDALDALVQ---------- MSMEG_5700|M.smegmatis_MC2_155 TETPDQIPGQGPNMTYLREIWHAIQTQDISGKDALLALTQRPLTTPDVPG MAB_0869c|M.abscessus_ATCC_199 TDVAP---GDSRGVSYLKDIVFAMQTQDVKASDAILALAQR--------- MMAR_4294|M.marinum_M TAYVFTAVGTPGPAEVQRLPLNVTWVNLTTGKSGSVTLKPRSDINPEGPT MUL_1004|M.ulcerans_Agy99 TAYVFTAVGTPGPAEVQRLPLNVTWVNLTTGKSGSVTLKPRSDINPEGPT MLBr_00568|M.leprae_Br4923 ---VPTASPQAALSGLVVLPGPPASVEAPPAAAPVVAAAT---------- TH_3373|M.thermoresistible__bu ---PTSSGPATGPTSVPREPGAGAGTTEPTAPAARAGEDGVGGDGTVG-- . . Mflv_3289|M.gilvum_PYR-GCK ---------------------GPQQAMSP-----VPPAPAPAP------- Mvan_3011|M.vanbaalenii_PYR-1 ---------------------SPSAGMPAGPQPVAPPAPAPVAPPVVP-- Mb0891c|M.bovis_AF2122/97 ----------------------PYVIG----------------------- Rv0867c|M.tuberculosis_H37Rv ----------------------PYVIG----------------------- MAV_0996|M.avium_104 ----------------------PAPSA----------------------- MSMEG_5700|M.smegmatis_MC2_155 GAAPNRPVAPPPAPGDPALAPAPAPLGAPAPAPAPEPAPVGAPAPVGAPV MAB_0869c|M.abscessus_ATCC_199 -------------------------------------------------- MMAR_4294|M.marinum_M TLTG------------IADTGSGSIMSTIFGQVTTKERQCQFMPTIGSTV MUL_1004|M.ulcerans_Agy99 TLTG------------IADTGSGSIMSTIFGQVTTKERQCQFMPTIGSTV MLBr_00568|M.leprae_Br4923 ----------------------PLLCCGEAAPPVR--------------- TH_3373|M.thermoresistible__bu -------------------GDGAFAEETVGEVPQLTATTTVVLPQSGAAD Mflv_3289|M.gilvum_PYR-GCK ---- Mvan_3011|M.vanbaalenii_PYR-1 ---- Mb0891c|M.bovis_AF2122/97 ---- Rv0867c|M.tuberculosis_H37Rv ---- MAV_0996|M.avium_104 ---- MSMEG_5700|M.smegmatis_MC2_155 PPPA MAB_0869c|M.abscessus_ATCC_199 ---- MMAR_4294|M.marinum_M VP-- MUL_1004|M.ulcerans_Agy99 VP-- MLBr_00568|M.leprae_Br4923 ---- TH_3373|M.thermoresistible__bu AAGD