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PHAADSHDLIRVTGARENNLKNVSLELPKRRLTVFTGVSGSGKSSLVFDTIAAESQRLINETYSAFVQGF MPSLARPDVDVLEGLTTAIIVDQQRLGADPRSTVGTATDTGAMLRILFSRLGQPHIGSPQAFSFNVASMS GAGAVTFDRGGKTVKERRDFAIVGGMCPRCEGRGAINDIDLSALYDDTKSLNDGALTIPGFSMEGWYGRI FNGCGFFDPDKPIRDFTAKELDALLHKEATKLKIDGVNLTYLGLIPQIKKSFLAKDVEAMQPHIRAFVER AVTFTTCPDCDGTRLSETARSSKINGVSIADVSAMQITDLAQWIDGVSETTGIEGVAPLLTALRHTLDSF VEIGLGYLSLDRPAGTLSGGEAQRVKMIRHLGSALTDVTYVFDEPTIGLHPHDIDRMNTLLVQLRDKGNT VLVVEHKPETIAIADHVVDLGPGAGTAGGDVVFEGTVDGLRRSDTLTGRHLDDRTSLKQSFRKAHGALKI RGADIHNLQNVDVDIPLGVLVVVTGVAGSGKSSLIDGSVAGRDGVVSVDQSPIRGSRRSNPATYTGALEP IRKAFAKANGVKPALFSSNSEGACPTCNGVGVVFTDLGVMATVESLCEECEGRRFQAEVLGYTLGGRDIA EVLAMPVAEAAAFFSEGEAKVAAAQKILDRMADVGLGYLTLGQPLTTLSGGERQRLKLASRLSDKGADEG SVYILDEPTTGLHLADVDQLLGLLDRLVDSGRSVIVIEHHQAVMAHADWIIDLGPGAGHDGGRIVFEGTP RQLVDSATTLTAKHLADYVRT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3006 | - | - | 100% (792) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_3339 | uvrA | e-116 | 36.72% (768) | excinuclease ABC subunit A |
| M. vanbaalenii PYR-1 | Mvan_1546 | - | 7e-09 | 37.25% (102) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1664 | uvrA | 1e-116 | 37.00% (773) | excinuclease ABC subunit A |
| M. gilvum PYR-GCK | Mflv_0951 | - | 1e-126 | 37.08% (855) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1638 | uvrA | 1e-116 | 37.00% (773) | excinuclease ABC subunit A |
| M. leprae Br4923 | MLBr_01392 | uvrA | 1e-113 | 35.51% (811) | excinuclease ABC subunit A |
| M. abscessus ATCC 19977 | MAB_2315 | uvrA | 1e-111 | 35.05% (796) | excinuclease ABC subunit A |
| M. marinum M | MMAR_2443 | uvrA | 1e-111 | 37.70% (679) | excinuclease ABC (subunit A-DNA-binding ATPase) UvrA |
| M. avium 104 | MAV_3135 | uvrA | 1e-112 | 37.59% (681) | excinuclease ABC subunit A |
| M. smegmatis MC2 155 | MSMEG_0211 | - | 0.0 | 84.52% (788) | ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_4658 | - | 0.0 | 80.48% (789) | PUTATIVE ABC transporter, ATP-binding protein |
| M. ulcerans Agy99 | MUL_1622 | uvrA | 1e-111 | 37.70% (679) | excinuclease ABC subunit A |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1664|M.bovis_AF2122/97 -----MADR----LIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSL
Rv1638|M.tuberculosis_H37Rv -----MADR----LIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSL
MMAR_2443|M.marinum_M -----MADR----LIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSL
MUL_1622|M.ulcerans_Agy99 -----MADR----LIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSL
MAV_3135|M.avium_104 -----MADR----LIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSL
MLBr_01392|M.leprae_Br4923 -----MADR----LIVKGAREHNLRSVDLDLPRDSLIVFTGLSGSGKSSL
MAB_2315|M.abscessus_ATCC_1997 -----MADR----LIVRGAREHNLRGIDLDLPRDSLIVFTGLSGSGKSSL
Mflv_0951|M.gilvum_PYR-GCK -----MTGEPDPYIRVFASRVHNLKTVDVAAPRDSFVAFTGVSGSGKSSL
Mvan_3006|M.vanbaalenii_PYR-1 ---MPHAADSHDLIRVTGARENNLKNVSLELPKRRLTVFTGVSGSGKSSL
MSMEG_0211|M.smegmatis_MC2_155 ----MHPADSHDRIRVTGARENNLKDIDIELPKRRLTVFTGVSGSGKSSL
TH_4658|M.thermoresistible__bu MTTDSHPADRHDLIRVLGARQNNLKNIDVEIPKRRLTVFTGVSGSGKSSL
. : * .:* :**: :.: *: : .***:********
Mb1664|M.bovis_AF2122/97 AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
Rv1638|M.tuberculosis_H37Rv AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MMAR_2443|M.marinum_M AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MUL_1622|M.ulcerans_Agy99 AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MAV_3135|M.avium_104 AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MLBr_01392|M.leprae_Br4923 AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MAB_2315|M.abscessus_ATCC_1997 AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
Mflv_0951|M.gilvum_PYR-GCK AFGTIYAEAQRRYFESVAPYARRLLLPQDAPKVDDITGLPPAVALQQRRG
Mvan_3006|M.vanbaalenii_PYR-1 VFDTIAAESQRLINETYSAFVQGFMPSLARPDVDVLEGLTTAIIVDQQRL
MSMEG_0211|M.smegmatis_MC2_155 VFDTIAAESQRLINETYSAFIQGFMPNQARPEVDVLEGLTTAIIVDQQRM
TH_4658|M.thermoresistible__bu VFDTIAAESQRLINETYSAFIQGFMPTPARPDVDMLDGLTAAIIVDQNRL
.*.** **.** *: :.: : :: *.** : **..*: ::*.
Mb1664|M.bovis_AF2122/97 NRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVL
Rv1638|M.tuberculosis_H37Rv NRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVL
MMAR_2443|M.marinum_M NRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERIARQTPQQIVDQVL
MUL_1622|M.ulcerans_Agy99 NRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERIARQTPQQIVDQVL
MAV_3135|M.avium_104 NRNPRSTVGTITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVL
MLBr_01392|M.leprae_Br4923 NRNPRSTVGTITEVYDYLRLLYARAGTPHCPICGEQISRQTPQQIVDQVL
MAB_2315|M.abscessus_ATCC_1997 NRNPRSTVGTITEVYDYLRLLYARAGTPHCPVCGEKIAKQTPQQIVDQVL
Mflv_0951|M.gilvum_PYR-GCK TATSRSTVGTVTTLSNLVRMLFSRAGT-----------------------
Mvan_3006|M.vanbaalenii_PYR-1 GADPRSTVGTATDTGAMLRILFSRLGQPHIGS------------------
MSMEG_0211|M.smegmatis_MC2_155 GSDPRSTVGTVTDAGAMLRILFSRLGKPHVGS------------------
TH_4658|M.thermoresistible__bu GADPRSTVGTVTDTGALLRILYSRLGEPHIGS------------------
.****** * :*:*::* *
Mb1664|M.bovis_AF2122/97 AMPEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPP
Rv1638|M.tuberculosis_H37Rv AMPEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPP
MMAR_2443|M.marinum_M AMAEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPP
MUL_1622|M.ulcerans_Agy99 AMAEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPP
MAV_3135|M.avium_104 AMPEGTRFLVLAPVVRTRKGEFADLFEKLNAQGYSRVRVDGVVHPLTDPP
MLBr_01392|M.leprae_Br4923 VLPEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDDVVYPLSDPP
MAB_2315|M.abscessus_ATCC_1997 DMEEGLRFQVLAPVVRTRKGEFVDLFEQLNSQGYSRIRVDGVVHSLTDPP
Mflv_0951|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3006|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0211|M.smegmatis_MC2_155 --------------------------------------------------
TH_4658|M.thermoresistible__bu --------------------------------------------------
Mb1664|M.bovis_AF2122/97 KLKKQEKHDIEVVVDRLTVKAAAKRRLTDSVETALNLADGIVVLEFVD-H
Rv1638|M.tuberculosis_H37Rv KLKKQEKHDIEVVVDRLTVKAAAKRRLTDSVETALNLADGIVVLEFVD-H
MMAR_2443|M.marinum_M KLKKQEKHDIEVVVDRLTVKAAAKQRLTDSVETALNLADGIVVLEFPDDH
MUL_1622|M.ulcerans_Agy99 KLKKQEKHDIEVVVDRLTVKAAAKQRLTDSVETALNLADGIVVLEFPDDH
MAV_3135|M.avium_104 KLKKQEKHDIEVVVDRLTVKASAKQRLTDSVETALNLADGIVVLEFVD-H
MLBr_01392|M.leprae_Br4923 KLKKQEKHDIEVVVDRLTVKIAAKQRLTDSVETALNLADGIVVLEFPDDH
MAB_2315|M.abscessus_ATCC_1997 KLKKQEKHDIEVVIDRLSVKASSKQRLTDSVETALHLADGIVVLEFVD-A
Mflv_0951|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3006|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0211|M.smegmatis_MC2_155 --------------------------------------------------
TH_4658|M.thermoresistible__bu --------------------------------------------------
Mb1664|M.bovis_AF2122/97 ELGAPHREQRFSEKLACPNGHALAVDDLEPRSFS----FNSPYGACPECS
Rv1638|M.tuberculosis_H37Rv ELGAPHREQRFSEKLACPNGHALAVDDLEPRSFS----FNSPYGACPECS
MMAR_2443|M.marinum_M DEHDHPREQRFSEKLACPNGHPLAVDDLEPRSFS----FNSPYGACPECS
MUL_1622|M.ulcerans_Agy99 DEHDHPREQRFSEKLACPNGHPLAVDDLEPRSFS----FNSPYGACPECS
MAV_3135|M.avium_104 EHDAHNREQRFSEKLACPNGHALAVDDLEPRSFS----FNSPYGACPECS
MLBr_01392|M.leprae_Br4923 DERGHPREQCFSEKLACPNGHPLAVDDLEPRSFS----FNSPYGACPECV
MAB_2315|M.abscessus_ATCC_1997 DEDSPQRERRFSEKLACPNGHPLAVDDLEPRSFS----FNSPYGACPECA
Mflv_0951|M.gilvum_PYR-GCK ----------------YPPG---ATERLDSDAFS----PNTTIGACPQCH
Mvan_3006|M.vanbaalenii_PYR-1 -------PQAFSFNVASMSGAGAVTFDRGGKTVKERRDFAIVGGMCPRCE
MSMEG_0211|M.smegmatis_MC2_155 -------PQAFSFNVASISGAGAVEFQKGGRTVKERRDFNIVGGMCPRCE
TH_4658|M.thermoresistible__bu -------PQAFSFNVASISGAGAVTVERGGRTVKERREFEIVGGMCPRCE
* . :.. * **.*
Mb1664|M.bovis_AF2122/97 GLGIRKEVDPELVVPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALG
Rv1638|M.tuberculosis_H37Rv GLGIRKEVDPELVVPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALG
MMAR_2443|M.marinum_M GLGIRKEVDPDLVVPDPDRTLAEGAVAPWSTGHTAEYFTRMLAGLGDALG
MUL_1622|M.ulcerans_Agy99 GLGIRKEVDPDLVVPDPDRTLAEGAVAPWSTGHTAEYFTRMLAGLGDALG
MAV_3135|M.avium_104 GLGIRKEVDPDLVVPDPERTLAEGAVAPWSTGHTAEYFTRMMAGLGDELG
MLBr_01392|M.leprae_Br4923 GLGIRKEIDSDLVVPDPDRTLAEGAVAPWSAGRTAEYFTRMMAGLGEKLG
MAB_2315|M.abscessus_ATCC_1997 GLGIKKEVDPDLVVPDPDMTLAEGAIAPWSMGQNADYFVRLMAGLGDALG
Mflv_0951|M.gilvum_PYR-GCK GLGRIHEVTEETLVPDPSLSIRDGAVAAWPGAWQGQNLRDILI----TLG
Mvan_3006|M.vanbaalenii_PYR-1 GRGAINDIDLSALYDD-TKSLNDGALTIPGFSMEG-WYGRIFNGCG---F
MSMEG_0211|M.smegmatis_MC2_155 GRGSVNDIDLTALYDD-SKSLNEGALTIPGFSMDG-WYGRIFRGCG---F
TH_4658|M.thermoresistible__bu GRGVINDIDRTALYDD-SKSLNEGALTIPGFSMDG-WYGRIFRGCG---F
* * ::: : * :: :**:: . . ::
Mb1664|M.bovis_AF2122/97 FDVDTPWRKLPAKARKAILEGADEQVHVRYRNRYGRTRSYYAD--FEGVL
Rv1638|M.tuberculosis_H37Rv FDVDTPWRKLPAKARKAILEGADEQVHVRYRNRYGRTRSYYAD--FEGVL
MMAR_2443|M.marinum_M FDVDTPWRKLPAKARKAILEGADEQVHVRYRNRYGRTRSYYAD--FEGVL
MUL_1622|M.ulcerans_Agy99 FDVDTPWRKLPAKARKAILEGADEQVHVRYRNRYGRTRSYYAD--FEGVL
MAV_3135|M.avium_104 FDVDTPWRKLPAKARKAILEGSDHQVHVRYRNRYGRTRSYYAD--FEGVL
MLBr_01392|M.leprae_Br4923 FDVDTPWRKLPAKARKAILEGSDHQVHVQYHNRYGRPRSYYVD--FEGVL
MAB_2315|M.abscessus_ATCC_1997 FDVDTPWKKLPAAAKKAILDGSSEQVHVRYKNRYGRTRSYYAE--FEGVL
Mflv_0951|M.gilvum_PYR-GCK YDIDKPWRKLTKRQRDWVLFTEDQPTVEIDPSRHPVTADYYYNGTFSSAE
Mvan_3006|M.vanbaalenii_PYR-1 FDPDKPIRDFTAKELDALLHKEATKLKIDGVN------LTYLG-LIPQIK
MSMEG_0211|M.smegmatis_MC2_155 FDPDKPIKKFTKKELDALLYKDATRLKIDGTN------LTYLG-LIPQIQ
TH_4658|M.thermoresistible__bu FDPDKPIREFTRKELDALLYKEPTKLKIDGVN------LTYMG-LIPQIH
:* *.* :.:. . :* . * :
Mb1664|M.bovis_AF2122/97 AFLQRKMSQTESEQMKERYEGFMRDVPCPVCAGTRLKPEILAVTLAGESK
Rv1638|M.tuberculosis_H37Rv AFLQRKMSQTESEQMKERYEGFMRDVPCPVCAGTRLKPEILAVTLAGESK
MMAR_2443|M.marinum_M AFLQRKMAQTESEQMKERYEGFMRDVPCPVCDGARLKPEILSVTLAA---
MUL_1622|M.ulcerans_Agy99 AFLQRKMAQTESEQMKERYEGFMRDVPCPVCDGARLKPEILSVTLAA---
MAV_3135|M.avium_104 AFLQRKMAQTESEQMKERYEGFMRDVPCPVCEGTRLKPEILAVTLAA---
MLBr_01392|M.leprae_Br4923 TFLQRKMEQTESEQMKERYEGFMRNIPCPVCQGTRLKPEILAVTLAA---
MAB_2315|M.abscessus_ATCC_1997 AFLQRRMEQTESEWAKERYEGFMRDIPCPVCEGTRLKPEILSVTLTA---
Mflv_0951|M.gilvum_PYR-GCK RHVRHTLANSQSAAMRRRVLQYVHSTDCPVCGGSGLRAEALAVTFAGRTI
Mvan_3006|M.vanbaalenii_PYR-1 KSFLAKDVEAMQPHIRAFVERAVTFTTCPDCDGTRLSETARSSKING---
MSMEG_0211|M.smegmatis_MC2_155 KSFLSKDVEAMQPHIRAFVERAVTFTTCPECDGTRLSETARSSKIDG---
TH_4658|M.thermoresistible__bu KSFLSKDVEAMQPHIRAFVERAVTFTTCPDCDGTRLSERARSSKING---
. :: . : : ** * *: * : .: .
Mb1664|M.bovis_AF2122/97 GEHGAKSIAEVCELSIADCADFLNALTLGPREQ----AIAGQVLKEIRSR
Rv1638|M.tuberculosis_H37Rv GEHGAKSIAEVCELSIADCADFLNALTLGPREQ----AIAGQVLKEIRSR
MMAR_2443|M.marinum_M GEQDAKSIAEVCELSISDCADFLNALTLGAREQ----AIAGQVLKEIQSR
MUL_1622|M.ulcerans_Agy99 GEQDAKSIAEVCELSISDCADFLNALTLGAREQ----AIAGQVLKEIQSR
MAV_3135|M.avium_104 GRHGKKSIAEVCELSISDCAEFLNTLTLGPREQ----AIAGQVLKEIQSR
MLBr_01392|M.leprae_Br4923 GERGAKSIAEVCELSIADCSAFLNALILGVREQ----AIAGQVLKEIQSR
MAB_2315|M.abscessus_ATCC_1997 GEHGTKSIAEVCDLSIADCAQFLGALTLGHREQ----AIAGQVLKEVQFR
Mflv_0951|M.gilvum_PYR-GCK AELVALPLTTLAEVLEPAATRTEFAAAYESTESGEFTEVATMIAADLVAR
Mvan_3006|M.vanbaalenii_PYR-1 -----VSIADVSAMQITDLAQWIDGVSETTGIEG-----VAPLLTALRHT
MSMEG_0211|M.smegmatis_MC2_155 -----VNIADASAMQITDLATWLAGLEKKATAKS-----VAPLLTALRHT
TH_4658|M.thermoresistible__bu -----RNIAEVSAWQISDLIDWVDDLRD----DS-----VAPLLGSLRHT
:: . . . . : :
Mb1664|M.bovis_AF2122/97 LGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPS
Rv1638|M.tuberculosis_H37Rv LGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPS
MMAR_2443|M.marinum_M LGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPS
MUL_1622|M.ulcerans_Agy99 LGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPS
MAV_3135|M.avium_104 LGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPS
MLBr_01392|M.leprae_Br4923 LGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPS
MAB_2315|M.abscessus_ATCC_1997 LGFLLDVGLQYLSLSRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPS
Mflv_0951|M.gilvum_PYR-GCK IGVLVDLGLGYLSLHRRTPTVSPGELQRLRLATQLRAGLFGVLYVLDEPS
Mvan_3006|M.vanbaalenii_PYR-1 LDSFVEIGLGYLSLDRPAGTLSGGEAQRVKMIRHLGSALTDVTYVFDEPT
MSMEG_0211|M.smegmatis_MC2_155 LDSFVEIGLGYLSLARPAGTLSGGEAQRVKMIRHLGSALTDVTYVFDEPT
TH_4658|M.thermoresistible__bu LRSFVDIGLGYLSLDRPAGTLSGGEAQRVKMVRHLGSPLTDVTYVFDEPT
: ::::** **** * : *:* ** **::: :: : * .* **:***:
Mb1664|M.bovis_AF2122/97 IGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWIVDIGPGAGE
Rv1638|M.tuberculosis_H37Rv IGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWIVDIGPGAGE
MMAR_2443|M.marinum_M IGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWVVDIGPGAGE
MUL_1622|M.ulcerans_Agy99 IGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWVVDIGPGAGE
MAV_3135|M.avium_104 IGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIAHADWIVDIGPRAGE
MLBr_01392|M.leprae_Br4923 IGLHQRDNRRLIETLTRLRALGNTLIVVEHDEDTIAHADWVVDIGPGAGE
MAB_2315|M.abscessus_ATCC_1997 IGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIKHADWVVDIGPAAGE
Mflv_0951|M.gilvum_PYR-GCK AGLHPADAEPLLEVLDRLRRAGNSLFVVEHDMDVVRRADWVVDVGPGAGE
Mvan_3006|M.vanbaalenii_PYR-1 IGLHPHDIDRMNTLLVQLRDKGNTVLVVEHKPETIAIADHVVDLGPGAGT
MSMEG_0211|M.smegmatis_MC2_155 IGLHPHDIARMNTLLLQLRDKGNTVLVVEHKPETIAIADHVVDLGPGAGT
TH_4658|M.thermoresistible__bu IGLHPHDIDRMNQLLLRLRDKGNTVLVVEHKPEVIAIADHIVDLGPGAGA
*** * : * :** **:::****. :.: ** :**:** **
Mb1664|M.bovis_AF2122/97 HGGRIVHSGPYDELLRNKDSITGAYLSGRESIEIPAIRRSVDPRRQLTVV
Rv1638|M.tuberculosis_H37Rv HGGRIVHSGPYDELLRNKDSITGAYLSGRESIEIPAIRRSVDPRRQLTVV
MMAR_2443|M.marinum_M HGGSIVHSGPYQELLRNQSSITGAFLSGREGIEIPTSRRSVDSRRQLTVV
MUL_1622|M.ulcerans_Agy99 HGGSIVHSGPYQELLRNQSSITGAFLSGREGIEIPTSRRSIDSRRQLTVV
MAV_3135|M.avium_104 HGGQIVHSGTYAELLANQDSITGAYLSGKESIEMPAIRRPVDRRRQLTVV
MLBr_01392|M.leprae_Br4923 HGGQIVHNGTYRELLANKDSITGAYLSGRESIATPTRRRSVDRKRELTVV
MAB_2315|M.abscessus_ATCC_1997 HGGQVVHSGTYAELLKNKNSVTGSYLSGAESIPLPLIRRVIDPKRQVTVV
Mflv_0951|M.gilvum_PYR-GCK LGGDVLYSGPVAGLANVDASVTRRFLFAEEARPARAPRTPASVMR---LR
Mvan_3006|M.vanbaalenii_PYR-1 AGGDVVFEGTVDGLRRS-DTLTGRHLDDRTSLKQSFR----KAHGALKIR
MSMEG_0211|M.smegmatis_MC2_155 AGGEVVFQGTVDGLRAS-DTVTGRHLGYRAALKDSVR----EPDGALEVR
TH_4658|M.thermoresistible__bu EGGEVVFAGSLDGLRAA-ATLTGRHLDDRAALKKKVR----TPTGVLPVR
** ::. *. * ::* .* . :
Mb1664|M.bovis_AF2122/97 GAREHNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGAR
Rv1638|M.tuberculosis_H37Rv GAREHNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGAR
MMAR_2443|M.marinum_M GAREHNLRGIDVAFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGAR
MUL_1622|M.ulcerans_Agy99 GAREHNLRGLDVAFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGAR
MAV_3135|M.avium_104 GAREHNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILATVLANRLNGAR
MLBr_01392|M.leprae_Br4923 GAREHNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGAR
MAB_2315|M.abscessus_ATCC_1997 GAREHNLKDIDVSFPLGVLTSVTGVSGSGKSTLVNDILATVLANKLNGAR
Mflv_0951|M.gilvum_PYR-GCK GITFHNLVGVDVDIPLGSFVAVTGVSGSGKSTLVCKVLGDVMARQLGRSP
Mvan_3006|M.vanbaalenii_PYR-1 GADIHNLQNVDVDIPLGVLVVVTGVAGSGKSSLIDGSVAGR---------
MSMEG_0211|M.smegmatis_MC2_155 GANTNNLHDVDVDIPLGVLVVITGVAGSGKSSLIDGSVAGR---------
TH_4658|M.thermoresistible__bu DAHTNNLQHIDVDIPLGVLVVLTGVAGSGKSSLIDGSVAGR---------
. :** :** :*** :. :***:*****:*: :.
Mb1664|M.bovis_AF2122/97 QVPGRHTR-----------------VTGLDYLDKLVRVDQSPIGRTPRSN
Rv1638|M.tuberculosis_H37Rv QVPGRHTR-----------------VTGLDYLDKLVRVDQSPIGRTPRSN
MMAR_2443|M.marinum_M QVPGRHTR-----------------ITGLDHLDKLVRVDQSPIGRTPRSN
MUL_1622|M.ulcerans_Agy99 QVPGRHTR-----------------ITGLDHLDKLVRVDQSPIGRTPRSN
MAV_3135|M.avium_104 LVPGRHTR-----------------VTGLDHLDKLVRVDQSPIGRTPRSN
MLBr_01392|M.leprae_Br4923 QVPGRHTR-----------------VTGLEHLDKLVRVDQSPIGRTPRSN
MAB_2315|M.abscessus_ATCC_1997 QVPGRHTR-----------------VTGLDKVDKLVRVDQSPIGRTPRSN
Mflv_0951|M.gilvum_PYR-GCK EPAEDAADGDAELLDIDVDSSVGVAVEGAEIIDRLVTVDQRPIGRTPRSN
Mvan_3006|M.vanbaalenii_PYR-1 --------------------------------DGVVSVDQSPIRGSRRSN
MSMEG_0211|M.smegmatis_MC2_155 --------------------------------EGVVLVDQSPIRGSRRSN
TH_4658|M.thermoresistible__bu --------------------------------DGVVTVDQSPLRGSRRSN
: :* *** *: : ***
Mb1664|M.bovis_AF2122/97 PATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIK
Rv1638|M.tuberculosis_H37Rv PATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIK
MMAR_2443|M.marinum_M PATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIK
MUL_1622|M.ulcerans_Agy99 PATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIK
MAV_3135|M.avium_104 PATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIK
MLBr_01392|M.leprae_Br4923 PATYTGVFDKIRILFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIK
MAB_2315|M.abscessus_ATCC_1997 PATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIK
Mflv_0951|M.gilvum_PYR-GCK LATYTGLFDAVRKAFADTPEARRRGWSAGRFSFNVAEGRCATCQGEGFVA
Mvan_3006|M.vanbaalenii_PYR-1 PATYTGALEPIRKAFAKANGVK-----PALFSSNS-EGACPTCNGVGVVF
MSMEG_0211|M.smegmatis_MC2_155 PATYTGLLEPIRKAFAKANGVK-----PALFSSNS-EGACPVCNGAGVIY
TH_4658|M.thermoresistible__bu PATYTGLLDPIRKAFAKANGVK-----PALFSSNS-EGACPLCNGAGIIY
***** :: :* ** : .: .. ** * * * * * * :
Mb1664|M.bovis_AF2122/97 IEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTVSEVLDMSIEEAAEFF
Rv1638|M.tuberculosis_H37Rv IEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTVSEVLDMSIEEAAEFF
MMAR_2443|M.marinum_M IEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTISEVLDMSIEEAADFF
MUL_1622|M.ulcerans_Agy99 IEMNFLPDVYVPCEVCQGARYNRETLEVHYNGKTISEVLDMSIEEAADFF
MAV_3135|M.avium_104 IEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKTISEVLDMSIEEAAEFF
MLBr_01392|M.leprae_Br4923 IEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKAISEVLDMSIEEAAEFF
MAB_2315|M.abscessus_ATCC_1997 IEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKTIAQVLDMPIEEAAEFF
Mflv_0951|M.gilvum_PYR-GCK VELLFLPGTYATCPACGGARYSDETLEVTYRDRTIADVLAQTVDEAADFL
Mvan_3006|M.vanbaalenii_PYR-1 TDLGVMATVESLCEECEGRRFQAEVLGYTLGGRDIAEVLAMPVAEAAAFF
MSMEG_0211|M.smegmatis_MC2_155 TDLGVMATMESPCEECEGRRFQATVLEYTLAHRNIAEVLEMPVTEAVEFF
TH_4658|M.thermoresistible__bu TELGVMATVETTCEECEGRRFQASVLAYELAGRNIADVLDMPVTEALDFF
:: .:. * * * *:. .* : :::** .: ** *:
Mb1664|M.bovis_AF2122/97 ----EPIAGVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQK
Rv1638|M.tuberculosis_H37Rv ----EPIAGVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQK
MMAR_2443|M.marinum_M ----EPISGIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQK
MUL_1622|M.ulcerans_Agy99 ----EPISGIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQK
MAV_3135|M.avium_104 ----EPITGIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLAAELQK
MLBr_01392|M.leprae_Br4923 ----EPIIGINRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQK
MAB_2315|M.abscessus_ATCC_1997 ----EPITSIHRYLKTLVEVGLGYVRLGQPAPTLSGGEAQRVKLAAELQK
Mflv_0951|M.gilvum_PYR-GCK ----TELPGAARSLTTLREVGLGYLRLGQPATELSGGEAQRIKLATELQR
Mvan_3006|M.vanbaalenii_PYR-1 SEGEAKVAAAQKILDRMADVGLGYLTLGQPLTTLSGGERQRLKLASRLSD
MSMEG_0211|M.smegmatis_MC2_155 GAGEAKVPAAQKILERMADVGLGYLTLGQPLTTLSGGERQRLKLAAQMAD
TH_4658|M.thermoresistible__bu TDAHP-LPAARRILERLADVGLGYLGLGQSLTTLSGGERQRLKLAARLGD
: . : * : :*****: ***. . ***** **:***:.:
Mb1664|M.bovis_AF2122/97 RSTG-RTVYILDEPTTGLHFDDIRKLLNVINGLVDKGNTVIVIEHNLDVI
Rv1638|M.tuberculosis_H37Rv RSTG-RTVYILDEPTTGLHFDDIRKLLNVINGLVDKGNTVIVIEHNLDVI
MMAR_2443|M.marinum_M RSTG-RTIYILDEPTTGLHFDDIRKLLNVISGLVDKGNTVVVIEHNLDVI
MUL_1622|M.ulcerans_Agy99 RSTG-RTIYILDEPTTGLHFDDIRKLLNVISGLVDKGNTVVVIEHNLDVI
MAV_3135|M.avium_104 RSTG-RTIYILDEPTTGLHFDDIRKLLKVINGLVDKGNTVIVIEHNLDVI
MLBr_01392|M.leprae_Br4923 RSTG-RTIYILDEPTTGLHFDDIRKLLNVINGLVDKDNTVIVIEHNLDVI
MAB_2315|M.abscessus_ATCC_1997 RSTG-KTIYILDEPTTGLHFEDIRKLLTVINGLVDKGNTVIVIEHNLDVI
Mflv_0951|M.gilvum_PYR-GCK AKRG-HTLYVLDEPTTGLHPADVELLERQLHRLVEAGNTVVVAEHDMAVV
Mvan_3006|M.vanbaalenii_PYR-1 KGADEGSVYILDEPTTGLHLADVDQLLGLLDRLVDSGRSVIVIEHHQAVM
MSMEG_0211|M.smegmatis_MC2_155 K----GNVYILDEPTTGLHLADVEQLLALLDRLVDSGKSVVVIEHHQAVM
TH_4658|M.thermoresistible__bu KGADAATVYVLDEPTNGLHLADVEQLLALLDRLVDAGKSVLVIEHHQAVM
.:*:*****.*** *: * : **: ..:*:* **. *:
Mb1664|M.bovis_AF2122/97 KTSDWIIDLGPEGGAGGGTVVAQGTPEDVAAVPASYTGKFLAEVVG----
Rv1638|M.tuberculosis_H37Rv KTSDWIIDLGPEGGAGGGTVVAQGTPEDVAAVPASYTGKFLAEVVG----
MMAR_2443|M.marinum_M KTSDWIIDMGPEGGAGGGTVVAQGAPEDIAAVPESYTGKFLAEVLA----
MUL_1622|M.ulcerans_Agy99 KTSDWIIDMGPEGGAGGGTVVAQGAPEDIAAVPESYTGKFLAEVLA----
MAV_3135|M.avium_104 KTSDWIVDMGPEGGAEGGTVVAQGTPEDVAAVPESYTGKFLAEVIGR---
MLBr_01392|M.leprae_Br4923 KTSDWIVDMGPEGGAQGGTVVAEGTPEDVAAVPESYTGKFLAEVVGA---
MAB_2315|M.abscessus_ATCC_1997 KTSDWIIDMGPEGGSGGGTVVAEGTPESVAQTAGSYTGEFLVDLLPRPVR
Mflv_0951|M.gilvum_PYR-GCK AGADHVIDLGPGGGDDGGTVVAAGTPSVVAAHASSRTAPYLAVQLR----
Mvan_3006|M.vanbaalenii_PYR-1 AHADWIIDLGPGAGHDGGRIVFEGTPRQLVDSATTLTAKHLADYVRT---
MSMEG_0211|M.smegmatis_MC2_155 AHADWIIDLGPGAGHDGGRIVFEGTPADLVAARSTLTGRHLAEYVSS---
TH_4658|M.thermoresistible__bu AHADWIIDLGPGAGHDGGHVVFEGTPADLVASRSTLTGRHLADYLRGG--
:* ::*:** .* ** :* *:* :. : *. .*. :
Mb1664|M.bovis_AF2122/97 -GGASAATSR-SN-------RRRNVSA--
Rv1638|M.tuberculosis_H37Rv -GGASAATSR-SN-------RRRNVSA--
MMAR_2443|M.marinum_M -ARRPSTTARRTN-------RRRKVSA--
MUL_1622|M.ulcerans_Agy99 -ARRPSTTARRTN-------RRRKVSA--
MAV_3135|M.avium_104 -GGAAAGAPRRSS-------RRRKATA--
MLBr_01392|M.leprae_Br4923 -GCAPARTPR----------RRRTVTA--
MAB_2315|M.abscessus_ATCC_1997 NGKAPAKAPAKSTGKTLAKARTRKVVTPV
Mflv_0951|M.gilvum_PYR-GCK -----------------------------
Mvan_3006|M.vanbaalenii_PYR-1 -----------------------------
MSMEG_0211|M.smegmatis_MC2_155 -----------------------------
TH_4658|M.thermoresistible__bu -----------------------------