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VADRLIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGQMD KPDVDFIEGLSPAVSIDQKSTNRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERIARQTPQQIVDQV LAMAEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHDIEVVVDRLTV KAAAKQRLTDSVETALNLADGIVVLEFPDDHDEHDHPREQRFSEKLACPNGHPLAVDDLEPRSFSFNSPY GACPECSGLGIRKEVDPDLVVPDPDRTLAEGAVAPWSTGHTAEYFTRMLAGLGDALGFDVDTPWRKLPAK ARKAILEGADEQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMAQTESEQMKERYEGFMRDVPCPVCDGAR LKPEILSVTLAAGEQDAKSIAEVCELSISDCADFLNALTLGAREQAIAGQVLKEIQSRLGFLLDVGLEYL SLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLRDLGNTLIVVEHDE DTIEHADWVVDIGPGAGEHGGSIVHSGPYQELLRNQSSITGAFLSGREGIEIPTSRRSIDSRRQLTVVGA REHNLRGLDVAFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRITGLDHLDKLVRVD QSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIKIEMNFLPDV YVPCEVCQGARYNRETLEVHYNGKTISEVLDMSIEEAADFFEPISGIHRYLRTLVDVGLGYVRLGQPAPT LSGGEAQRVKLASELQKRSTGRTIYILDEPTTGLHFDDIRKLLNVISGLVDKGNTVVVIEHNLDVIKTSD WIIDMGPEGGAGGGTVVAQGAPEDIAAVPESYTGKFLAEVLAARRPSTTARRTNRRRKVSA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_1622 | uvrA | - | 100% (971) | excinuclease ABC subunit A |
M. ulcerans Agy99 | MUL_3149 | - | 4e-08 | 30.83% (120) | transmembrane ATP-binding protein ABC transporter |
M. ulcerans Agy99 | MUL_1424 | - | 1e-07 | 34.74% (95) | transmembrane ATP-binding protein ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1664 | uvrA | 0.0 | 92.81% (974) | excinuclease ABC subunit A |
M. gilvum PYR-GCK | Mflv_3548 | uvrA | 0.0 | 88.77% (971) | excinuclease ABC subunit A |
M. tuberculosis H37Rv | Rv1638 | uvrA | 0.0 | 92.81% (974) | excinuclease ABC subunit A |
M. leprae Br4923 | MLBr_01392 | uvrA | 0.0 | 90.53% (971) | excinuclease ABC subunit A |
M. abscessus ATCC 19977 | MAB_2315 | uvrA | 0.0 | 86.54% (951) | excinuclease ABC subunit A |
M. marinum M | MMAR_2443 | uvrA | 0.0 | 99.69% (971) | excinuclease ABC (subunit A-DNA-binding ATPase) UvrA |
M. avium 104 | MAV_3135 | uvrA | 0.0 | 92.28% (972) | excinuclease ABC subunit A |
M. smegmatis MC2 155 | MSMEG_3808 | uvrA | 0.0 | 87.95% (971) | excinuclease ABC subunit A |
M. thermoresistible (build 8) | TH_1581 | uvrA | 0.0 | 87.31% (969) | excinuclease ABC, A subunit |
M. vanbaalenii PYR-1 | Mvan_3339 | uvrA | 0.0 | 89.08% (971) | excinuclease ABC subunit A |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3548|M.gilvum_PYR-GCK MADRLVVKGAREHNLRGVDLDLPRDAMIVFTGLSGSGKSSLAFDTIFAEG Mvan_3339|M.vanbaalenii_PYR-1 MADRLVVKGAREHNLRGVDLDLPRDAMIVFTGLSGSGKSSLAFDTIFAEG MSMEG_3808|M.smegmatis_MC2_155 MADRLVVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG TH_1581|M.thermoresistible__bu LADRLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG MUL_1622|M.ulcerans_Agy99 MADRLIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG MMAR_2443|M.marinum_M MADRLIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG Mb1664|M.bovis_AF2122/97 MADRLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG Rv1638|M.tuberculosis_H37Rv MADRLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG MLBr_01392|M.leprae_Br4923 MADRLIVKGAREHNLRSVDLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEG MAV_3135|M.avium_104 MADRLIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG MAB_2315|M.abscessus_ATCC_1997 MADRLIVRGAREHNLRGIDLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEG :****:*:********.:*******::*********************** Mflv_3548|M.gilvum_PYR-GCK QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG Mvan_3339|M.vanbaalenii_PYR-1 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG MSMEG_3808|M.smegmatis_MC2_155 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG TH_1581|M.thermoresistible__bu QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG MUL_1622|M.ulcerans_Agy99 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG MMAR_2443|M.marinum_M QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG Mb1664|M.bovis_AF2122/97 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG Rv1638|M.tuberculosis_H37Rv QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG MLBr_01392|M.leprae_Br4923 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG MAV_3135|M.avium_104 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG MAB_2315|M.abscessus_ATCC_1997 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG ************************************************** Mflv_3548|M.gilvum_PYR-GCK TITEVYDYLRLLYARAGTPHCPVCGERIAKQTPQQIVDQVLAMDEGLRFQ Mvan_3339|M.vanbaalenii_PYR-1 TITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVLAMDEGLRFQ MSMEG_3808|M.smegmatis_MC2_155 TITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVLAMDEGLRFQ TH_1581|M.thermoresistible__bu TITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVLAMDEGLRFQ MUL_1622|M.ulcerans_Agy99 TITEVYDYLRLLYARAGTPHCPTCGERIARQTPQQIVDQVLAMAEGTRFL MMAR_2443|M.marinum_M TITEVYDYLRLLYARAGTPHCPTCGERIARQTPQQIVDQVLAMAEGTRFL Mb1664|M.bovis_AF2122/97 TITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVLAMPEGTRFL Rv1638|M.tuberculosis_H37Rv TITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVLAMPEGTRFL MLBr_01392|M.leprae_Br4923 TITEVYDYLRLLYARAGTPHCPICGEQISRQTPQQIVDQVLVLPEGTRFL MAV_3135|M.avium_104 TITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVLAMPEGTRFL MAB_2315|M.abscessus_ATCC_1997 TITEVYDYLRLLYARAGTPHCPVCGEKIAKQTPQQIVDQVLDMEEGLRFQ ********************** ***::::*********** : ** ** Mflv_3548|M.gilvum_PYR-GCK VLAPVVRTRKGEFVDLFDKLNTQGYSRVRVDGVVYPLTDPPKLKKQEKHD Mvan_3339|M.vanbaalenii_PYR-1 VLAPVVRTRKGEFVDLFDKLNSQGYSRVRVDGVVHPLTDPPKLKKQEKHD MSMEG_3808|M.smegmatis_MC2_155 VLAPVVRTRKGEFVDLFEKLNSQGYSRVRVDGVVYPLTDPPKLKKQEKHD TH_1581|M.thermoresistible__bu VLAPVVRTRKGEFVDLFDKLNSQGYSRVRVDGVVYPLTDPPKLKKQEKHD MUL_1622|M.ulcerans_Agy99 VLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHD MMAR_2443|M.marinum_M VLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHD Mb1664|M.bovis_AF2122/97 VLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHD Rv1638|M.tuberculosis_H37Rv VLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHD MLBr_01392|M.leprae_Br4923 VLAPVVRTRKGEFADLFDKLNAQGYSRVRVDDVVYPLSDPPKLKKQEKHD MAV_3135|M.avium_104 VLAPVVRTRKGEFADLFEKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHD MAB_2315|M.abscessus_ATCC_1997 VLAPVVRTRKGEFVDLFEQLNSQGYSRIRVDGVVHSLTDPPKLKKQEKHD *************.***::**:*****:***.**:.*:************ Mflv_3548|M.gilvum_PYR-GCK IEVVVDRLTVKASSKQRLTDSIETALNLADGIVVLEFVD-REDDHPHREQ Mvan_3339|M.vanbaalenii_PYR-1 IEVVVDRLTVKATAKQRLTDSVETALNLADGIVVLEFVD-REDDHPHREQ MSMEG_3808|M.smegmatis_MC2_155 IEVVVDRLTVKASAKQRLTDSIETALNLADGIVVLEFVD-REDDHPHREQ TH_1581|M.thermoresistible__bu IEVVVDRLTVKPSAKQRLTDSIETALNLADGIVVLDFVD-RDEDDPHREQ MUL_1622|M.ulcerans_Agy99 IEVVVDRLTVKAAAKQRLTDSVETALNLADGIVVLEFPDDHDEHDHPREQ MMAR_2443|M.marinum_M IEVVVDRLTVKAAAKQRLTDSVETALNLADGIVVLEFPDDHDEHDHPREQ Mb1664|M.bovis_AF2122/97 IEVVVDRLTVKAAAKRRLTDSVETALNLADGIVVLEFVD-HELGAPHREQ Rv1638|M.tuberculosis_H37Rv IEVVVDRLTVKAAAKRRLTDSVETALNLADGIVVLEFVD-HELGAPHREQ MLBr_01392|M.leprae_Br4923 IEVVVDRLTVKIAAKQRLTDSVETALNLADGIVVLEFPDDHDERGHPREQ MAV_3135|M.avium_104 IEVVVDRLTVKASAKQRLTDSVETALNLADGIVVLEFVD-HEHDAHNREQ MAB_2315|M.abscessus_ATCC_1997 IEVVIDRLSVKASSKQRLTDSVETALHLADGIVVLEFVD-ADEDSPQRER ****:***:** ::*:*****:****:********:* * : **: Mflv_3548|M.gilvum_PYR-GCK RFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECLGLGIRKEVDPDLV Mvan_3339|M.vanbaalenii_PYR-1 RFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECTGLGIRKEVDPDLV MSMEG_3808|M.smegmatis_MC2_155 RFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECTGLGIRKEVDPDLV TH_1581|M.thermoresistible__bu RFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECAGLGIRKEVDVDLV MUL_1622|M.ulcerans_Agy99 RFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECSGLGIRKEVDPDLV MMAR_2443|M.marinum_M RFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECSGLGIRKEVDPDLV Mb1664|M.bovis_AF2122/97 RFSEKLACPNGHALAVDDLEPRSFSFNSPYGACPECSGLGIRKEVDPELV Rv1638|M.tuberculosis_H37Rv RFSEKLACPNGHALAVDDLEPRSFSFNSPYGACPECSGLGIRKEVDPELV MLBr_01392|M.leprae_Br4923 CFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECVGLGIRKEIDSDLV MAV_3135|M.avium_104 RFSEKLACPNGHALAVDDLEPRSFSFNSPYGACPECSGLGIRKEVDPDLV MAB_2315|M.abscessus_ATCC_1997 RFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECAGLGIKKEVDPDLV ***********.*********************** ****:**:* :** Mflv_3548|M.gilvum_PYR-GCK VPDPDLTLAEGAIAPWSMGNTADYFTRMLSGLGDQLGFDVNTPWKKLPAK Mvan_3339|M.vanbaalenii_PYR-1 VPDPDLTLAEGAIAPWSMGHTAEYFTRMLSGLGDQLGFDVNTPWKKLPAK MSMEG_3808|M.smegmatis_MC2_155 VPDPELTLAEGAVAPWSVGQSAEYFTRMLAGLGEEMGFDVNTPWKKLPAK TH_1581|M.thermoresistible__bu VPDPDLTLAEGAIAPWSMGQTAEYFTRMLAGLGEAMGFDVDTPWRKLPAK MUL_1622|M.ulcerans_Agy99 VPDPDRTLAEGAVAPWSTGHTAEYFTRMLAGLGDALGFDVDTPWRKLPAK MMAR_2443|M.marinum_M VPDPDRTLAEGAVAPWSTGHTAEYFTRMLAGLGDALGFDVDTPWRKLPAK Mb1664|M.bovis_AF2122/97 VPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALGFDVDTPWRKLPAK Rv1638|M.tuberculosis_H37Rv VPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALGFDVDTPWRKLPAK MLBr_01392|M.leprae_Br4923 VPDPDRTLAEGAVAPWSAGRTAEYFTRMMAGLGEKLGFDVDTPWRKLPAK MAV_3135|M.avium_104 VPDPERTLAEGAVAPWSTGHTAEYFTRMMAGLGDELGFDVDTPWRKLPAK MAB_2315|M.abscessus_ATCC_1997 VPDPDMTLAEGAIAPWSMGQNADYFVRLMAGLGDALGFDVDTPWKKLPAA ****: ***:**:**** *..*:**.*:::***: :****:***:**** Mflv_3548|M.gilvum_PYR-GCK ARKAILEGCDEQVHVRYKNRYGRTRSYYADFEGVMAFLQRRMEQTDSEQT Mvan_3339|M.vanbaalenii_PYR-1 ARRAILEGCDEQVHVRYKNRYGRTRSYYADFEGVMAFLQRRMEQTDSEQM MSMEG_3808|M.smegmatis_MC2_155 ARRAILEGCDHQVHVRYKNRYGRTRSYYADFEGVMAFLQRRMEQTDSEQM TH_1581|M.thermoresistible__bu VRKAILEGCDEQVHVRYKNRYGRVRSYYADFEGVMAYLHRRMEQTDSEQM MUL_1622|M.ulcerans_Agy99 ARKAILEGADEQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMAQTESEQM MMAR_2443|M.marinum_M ARKAILEGADEQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMAQTESEQM Mb1664|M.bovis_AF2122/97 ARKAILEGADEQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMSQTESEQM Rv1638|M.tuberculosis_H37Rv ARKAILEGADEQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMSQTESEQM MLBr_01392|M.leprae_Br4923 ARKAILEGSDHQVHVQYHNRYGRPRSYYVDFEGVLTFLQRKMEQTESEQM MAV_3135|M.avium_104 ARKAILEGSDHQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMAQTESEQM MAB_2315|M.abscessus_ATCC_1997 AKKAILDGSSEQVHVRYKNRYGRTRSYYAEFEGVLAFLQRRMEQTESEWA .::***:*...****:*:***** ****.:****:::*:*:* **:** Mflv_3548|M.gilvum_PYR-GCK KERLEGFMRDVPCPECDGTRLKPEILAVTMTA---GTFGAKSIAEVSELS Mvan_3339|M.vanbaalenii_PYR-1 KERLEGFMRDVPCPECDGTRLKPEILAVTMTA---GNFGAKSIAEVAELS MSMEG_3808|M.smegmatis_MC2_155 KERYEGFMRDIPCPECNGTRLKPEILAVTLSA---GDFGAKSIAQVAELS TH_1581|M.thermoresistible__bu KERLEGFMRDVPCPECGGTRLKPEILAVTLSA---GEFGEKSIAEVADLS MUL_1622|M.ulcerans_Agy99 KERYEGFMRDVPCPVCDGARLKPEILSVTLAA---GEQDAKSIAEVCELS MMAR_2443|M.marinum_M KERYEGFMRDVPCPVCDGARLKPEILSVTLAA---GEQDAKSIAEVCELS Mb1664|M.bovis_AF2122/97 KERYEGFMRDVPCPVCAGTRLKPEILAVTLAGESKGEHGAKSIAEVCELS Rv1638|M.tuberculosis_H37Rv KERYEGFMRDVPCPVCAGTRLKPEILAVTLAGESKGEHGAKSIAEVCELS MLBr_01392|M.leprae_Br4923 KERYEGFMRNIPCPVCQGTRLKPEILAVTLAA---GERGAKSIAEVCELS MAV_3135|M.avium_104 KERYEGFMRDVPCPVCEGTRLKPEILAVTLAA---GRHGKKSIAEVCELS MAB_2315|M.abscessus_ATCC_1997 KERYEGFMRDIPCPVCEGTRLKPEILSVTLTA---GEHGTKSIAEVCDLS *** *****::*** * *:*******:**::. * . ****:*.:** Mflv_3548|M.gilvum_PYR-GCK IADCAAFLNALTLGTREAAIAGQVLKEIQSRLGFLLDVGLDYLSLSRAAG Mvan_3339|M.vanbaalenii_PYR-1 IADCAEFLNALTLGTREAAIAGQVLKEIQSRLGFLLDVGLDYLSLSRAAG MSMEG_3808|M.smegmatis_MC2_155 IADCADFLNSLTLGPREQAIAGQVLKEIQSRLGFLLDVGLDYLSLSRAAA TH_1581|M.thermoresistible__bu IADCAEFLNALTLGPREQAIAGQVLKEIQSRLGFLLDVGLDYLSLSRAAA MUL_1622|M.ulcerans_Agy99 ISDCADFLNALTLGAREQAIAGQVLKEIQSRLGFLLDVGLEYLSLSRAAA MMAR_2443|M.marinum_M ISDCADFLNALTLGAREQAIAGQVLKEIQSRLGFLLDVGLEYLSLSRAAA Mb1664|M.bovis_AF2122/97 IADCADFLNALTLGPREQAIAGQVLKEIRSRLGFLLDVGLEYLSLSRAAA Rv1638|M.tuberculosis_H37Rv IADCADFLNALTLGPREQAIAGQVLKEIRSRLGFLLDVGLEYLSLSRAAA MLBr_01392|M.leprae_Br4923 IADCSAFLNALILGVREQAIAGQVLKEIQSRLGFLLDVGLEYLSLSRAAA MAV_3135|M.avium_104 ISDCAEFLNTLTLGPREQAIAGQVLKEIQSRLGFLLDVGLEYLSLSRAAA MAB_2315|M.abscessus_ATCC_1997 IADCAQFLGALTLGHREQAIAGQVLKEVQFRLGFLLDVGLQYLSLSRAAG *:**: **.:* ** ** *********:: **********:********. Mflv_3548|M.gilvum_PYR-GCK TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIDTLVRLR Mvan_3339|M.vanbaalenii_PYR-1 TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIDTLVRLR MSMEG_3808|M.smegmatis_MC2_155 TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIDTLVRLR TH_1581|M.thermoresistible__bu TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIDTLVRLR MUL_1622|M.ulcerans_Agy99 TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLR MMAR_2443|M.marinum_M TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLR Mb1664|M.bovis_AF2122/97 TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLR Rv1638|M.tuberculosis_H37Rv TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLR MLBr_01392|M.leprae_Br4923 TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLR MAV_3135|M.avium_104 TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLR MAB_2315|M.abscessus_ATCC_1997 TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLR *******************************************:**.*** Mflv_3548|M.gilvum_PYR-GCK DLGNTLIVVEHDLDTIAHADWVVDIGPAAGEHGGQIVHSGTYADLLTNPE Mvan_3339|M.vanbaalenii_PYR-1 DLGNTLIVVEHDLDTIAHADWVVDIGPAAGEHGGQIVHSGTYEDLLRNPN MSMEG_3808|M.smegmatis_MC2_155 DLGNTLIVVEHDLDTIAHADWVVDIGPAAGEHGGQIVHSGTYDDLLRNPE TH_1581|M.thermoresistible__bu DLGNTLIVVEHDLDTIAHADWVVDIGPAAGEHGGRIVHSGPYADLLANPD MUL_1622|M.ulcerans_Agy99 DLGNTLIVVEHDEDTIEHADWVVDIGPGAGEHGGSIVHSGPYQELLRNQS MMAR_2443|M.marinum_M DLGNTLIVVEHDEDTIEHADWVVDIGPGAGEHGGSIVHSGPYQELLRNQS Mb1664|M.bovis_AF2122/97 DLGNTLIVVEHDEDTIEHADWIVDIGPGAGEHGGRIVHSGPYDELLRNKD Rv1638|M.tuberculosis_H37Rv DLGNTLIVVEHDEDTIEHADWIVDIGPGAGEHGGRIVHSGPYDELLRNKD MLBr_01392|M.leprae_Br4923 ALGNTLIVVEHDEDTIAHADWVVDIGPGAGEHGGQIVHNGTYRELLANKD MAV_3135|M.avium_104 DLGNTLIVVEHDEDTIAHADWIVDIGPRAGEHGGQIVHSGTYAELLANQD MAB_2315|M.abscessus_ATCC_1997 DLGNTLIVVEHDEDTIKHADWVVDIGPAAGEHGGQVVHSGTYAELLKNKN *********** *** ****:***** ****** :**.*.* :** * . Mflv_3548|M.gilvum_PYR-GCK SITGAYLSGKEEIEVPTMRRVVDKKRQLTVVGAREHNLREIDVSFPLGVL Mvan_3339|M.vanbaalenii_PYR-1 SITGAYLSGKEEIEVPDMRRVVDRKRQLTVVGAREHNLREIDVAFPLGVL MSMEG_3808|M.smegmatis_MC2_155 SLTGAYLSGKESIEVPAIRRPVDKKRQITVVGARENNLKEIDVAFPLGVL TH_1581|M.thermoresistible__bu SLTGEYLSGKKSIEVPAMRRPVDRKRQLTVVGARENNLRDIDVSFPLGVL MUL_1622|M.ulcerans_Agy99 SITGAFLSGREGIEIPTSRRSIDSRRQLTVVGAREHNLRGLDVAFPLGVL MMAR_2443|M.marinum_M SITGAFLSGREGIEIPTSRRSVDSRRQLTVVGAREHNLRGIDVAFPLGVL Mb1664|M.bovis_AF2122/97 SITGAYLSGRESIEIPAIRRSVDPRRQLTVVGAREHNLRGIDVSFPLGVL Rv1638|M.tuberculosis_H37Rv SITGAYLSGRESIEIPAIRRSVDPRRQLTVVGAREHNLRGIDVSFPLGVL MLBr_01392|M.leprae_Br4923 SITGAYLSGRESIATPTRRRSVDRKRELTVVGAREHNLRGIDVSFPLGVL MAV_3135|M.avium_104 SITGAYLSGKESIEMPAIRRPVDRRRQLTVVGAREHNLRGIDVSFPLGVL MAB_2315|M.abscessus_ATCC_1997 SVTGSYLSGAESIPLPLIRRVIDPKRQVTVVGAREHNLKDIDVSFPLGVL *:** :*** : * * ** :* :*::*******:**: :**:****** Mflv_3548|M.gilvum_PYR-GCK TSVTGVSGSGKSTLVNDILASVLANKLNGARLVPGRHTRINGLDHLDKLV Mvan_3339|M.vanbaalenii_PYR-1 TSVTGVSGSGKSTLVNDILASVLANKLNGARLVPGRHTRVNGLDHLDKLV MSMEG_3808|M.smegmatis_MC2_155 TSVTGVSGSGKSTMVNDILATVLANKLNGARLVPGRHTRVNGLDQLDKLV TH_1581|M.thermoresistible__bu TAVTGVSGSGKSTLVNDILAAALANKLNGARLVPGRHTRVNGLGEVDKLV MUL_1622|M.ulcerans_Agy99 TSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRITGLDHLDKLV MMAR_2443|M.marinum_M TSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRITGLDHLDKLV Mb1664|M.bovis_AF2122/97 TSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRVTGLDYLDKLV Rv1638|M.tuberculosis_H37Rv TSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRVTGLDYLDKLV MLBr_01392|M.leprae_Br4923 TSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRVTGLEHLDKLV MAV_3135|M.avium_104 TSVTGVSGSGKSTLVNDILATVLANRLNGARLVPGRHTRVTGLDHLDKLV MAB_2315|M.abscessus_ATCC_1997 TSVTGVSGSGKSTLVNDILATVLANKLNGARQVPGRHTRVTGLDKVDKLV *:***********:******:.***:***** *******:.** :**** Mflv_3548|M.gilvum_PYR-GCK RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK Mvan_3339|M.vanbaalenii_PYR-1 RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK MSMEG_3808|M.smegmatis_MC2_155 RVDQSPIGRTPRSNPATYTGVFDKIRSLFAATTEAKVRGYQPGRFSFNVK TH_1581|M.thermoresistible__bu RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK MUL_1622|M.ulcerans_Agy99 RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK MMAR_2443|M.marinum_M RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK Mb1664|M.bovis_AF2122/97 RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK Rv1638|M.tuberculosis_H37Rv RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK MLBr_01392|M.leprae_Br4923 RVDQSPIGRTPRSNPATYTGVFDKIRILFAATTEAKVRGYQPGRFSFNVK MAV_3135|M.avium_104 RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK MAB_2315|M.abscessus_ATCC_1997 RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK ************************** *********************** Mflv_3548|M.gilvum_PYR-GCK GGRCEACSGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTIA Mvan_3339|M.vanbaalenii_PYR-1 GGRCEACSGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTIA MSMEG_3808|M.smegmatis_MC2_155 GGRCEACSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKTIS TH_1581|M.thermoresistible__bu GGRCEACSGDGTLKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKTIA MUL_1622|M.ulcerans_Agy99 GGRCEACTGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYNGKTIS MMAR_2443|M.marinum_M GGRCEACTGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTIS Mb1664|M.bovis_AF2122/97 GGRCEACTGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTVS Rv1638|M.tuberculosis_H37Rv GGRCEACTGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTVS MLBr_01392|M.leprae_Br4923 GGRCEACTGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKAIS MAV_3135|M.avium_104 GGRCEACTGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKTIS MAB_2315|M.abscessus_ATCC_1997 GGRCEACTGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKTIA *******:****:*****************:*************:**::: Mflv_3548|M.gilvum_PYR-GCK EVLDMSIEEAAEFFAPISSIHRYLKTLVDVGLGYVRLGQPAPTLSGGEAQ Mvan_3339|M.vanbaalenii_PYR-1 EVLDMSIEEAAEFFAPISSIHRYLKTLVDVGLGYVRLGQPAPTLSGGEAQ MSMEG_3808|M.smegmatis_MC2_155 EVLDMSIEEATEFFEPISSIHRYLKTLVDVGLGYVRLGQPAPTLSGGEAQ TH_1581|M.thermoresistible__bu EVLDMSIEEAAEFFAPISSIHRYLQTLVDVGLGYVRLGQPAPTLSGGEAQ MUL_1622|M.ulcerans_Agy99 EVLDMSIEEAADFFEPISGIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQ MMAR_2443|M.marinum_M EVLDMSIEEAADFFEPISGIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQ Mb1664|M.bovis_AF2122/97 EVLDMSIEEAAEFFEPIAGVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQ Rv1638|M.tuberculosis_H37Rv EVLDMSIEEAAEFFEPIAGVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQ MLBr_01392|M.leprae_Br4923 EVLDMSIEEAAEFFEPIIGINRYLRTLVDVGLGYVRLGQPAPTLSGGEAQ MAV_3135|M.avium_104 EVLDMSIEEAAEFFEPITGIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQ MAB_2315|M.abscessus_ATCC_1997 QVLDMPIEEAAEFFEPITSIHRYLKTLVEVGLGYVRLGQPAPTLSGGEAQ :****.****::** ** .::***:***:********************* Mflv_3548|M.gilvum_PYR-GCK RVKLASELQKRSTGRTIYILDEPTTGLHFEDIRKLLTVINGLVDKGNTVI Mvan_3339|M.vanbaalenii_PYR-1 RVKLASELQKRSTGRTIYILDEPTTGLHFEDIRKLLTVINGLVDKGNTVI MSMEG_3808|M.smegmatis_MC2_155 RVKLAAELQKRSTGRTIYILDEPTTGLHFEDIRKLLKVINGLVDKGNTVI TH_1581|M.thermoresistible__bu RVKLASELQKRSTGRTVYILDEPTTGLHFEDIRKLLGVINGLVDKGNTVI MUL_1622|M.ulcerans_Agy99 RVKLASELQKRSTGRTIYILDEPTTGLHFDDIRKLLNVISGLVDKGNTVV MMAR_2443|M.marinum_M RVKLASELQKRSTGRTIYILDEPTTGLHFDDIRKLLNVISGLVDKGNTVV Mb1664|M.bovis_AF2122/97 RVKLASELQKRSTGRTVYILDEPTTGLHFDDIRKLLNVINGLVDKGNTVI Rv1638|M.tuberculosis_H37Rv RVKLASELQKRSTGRTVYILDEPTTGLHFDDIRKLLNVINGLVDKGNTVI MLBr_01392|M.leprae_Br4923 RVKLASELQKRSTGRTIYILDEPTTGLHFDDIRKLLNVINGLVDKDNTVI MAV_3135|M.avium_104 RVKLAAELQKRSTGRTIYILDEPTTGLHFDDIRKLLKVINGLVDKGNTVI MAB_2315|M.abscessus_ATCC_1997 RVKLAAELQKRSTGKTIYILDEPTTGLHFEDIRKLLTVINGLVDKGNTVI *****:********:*:************:****** **.*****.***: Mflv_3548|M.gilvum_PYR-GCK VIEHNLDVIKTSDWIIDMGPEGGSGGGTVVATGAPEDVAMNPDSYTGHFL Mvan_3339|M.vanbaalenii_PYR-1 VIEHNLDVIKTSDWVVDMGPEGGSGGGTVVATGTPEDVAANPDSYTGHFL MSMEG_3808|M.smegmatis_MC2_155 VIEHNLDVIKTSDWIIDMGPEGGAGGGTVVAQGTPEDVAANPDSYTGKFL TH_1581|M.thermoresistible__bu VIEHNLDVIKTADWIIDMGPEGGNGGGTVVAQGTPEDVAANPDSYTGQFL MUL_1622|M.ulcerans_Agy99 VIEHNLDVIKTSDWIIDMGPEGGAGGGTVVAQGAPEDIAAVPESYTGKFL MMAR_2443|M.marinum_M VIEHNLDVIKTSDWIIDMGPEGGAGGGTVVAQGAPEDIAAVPESYTGKFL Mb1664|M.bovis_AF2122/97 VIEHNLDVIKTSDWIIDLGPEGGAGGGTVVAQGTPEDVAAVPASYTGKFL Rv1638|M.tuberculosis_H37Rv VIEHNLDVIKTSDWIIDLGPEGGAGGGTVVAQGTPEDVAAVPASYTGKFL MLBr_01392|M.leprae_Br4923 VIEHNLDVIKTSDWIVDMGPEGGAQGGTVVAEGTPEDVAAVPESYTGKFL MAV_3135|M.avium_104 VIEHNLDVIKTSDWIVDMGPEGGAEGGTVVAQGTPEDVAAVPESYTGKFL MAB_2315|M.abscessus_ATCC_1997 VIEHNLDVIKTSDWIIDMGPEGGSGGGTVVAEGTPESVAQTAGSYTGEFL ***********:**::*:***** ****** *:**.:* . ****.** Mflv_3548|M.gilvum_PYR-GCK AETLGMN----------RPKPK------ARARRKVSA-- Mvan_3339|M.vanbaalenii_PYR-1 AETLGVA----------RPKPK------SRRRSKVSA-- MSMEG_3808|M.smegmatis_MC2_155 AELLDVP----------TPK---------RKRRKVSA-- TH_1581|M.thermoresistible__bu AEILDVP----------APT---------RKRRKVQVSA MUL_1622|M.ulcerans_Agy99 AEVLAARR------PSTTARR-------TNRRRKVSA-- MMAR_2443|M.marinum_M AEVLAARR------PSTTARR-------TNRRRKVSA-- Mb1664|M.bovis_AF2122/97 AEVVGGGA------SAATSR--------SNRRRNVSA-- Rv1638|M.tuberculosis_H37Rv AEVVGGGA------SAATSR--------SNRRRNVSA-- MLBr_01392|M.leprae_Br4923 AEVVGAG--------CAPART-------PRRRRTVTA-- MAV_3135|M.avium_104 AEVIGRGG------AAAGAPRR------SSRRRKATA-- MAB_2315|M.abscessus_ATCC_1997 VDLLPRPVRNGKAPAKAPAKSTGKTLAKARTRKVVTPV- .: : . * .