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ADRLVVKGAREHNLRGVDLDLPRDAMIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGQMDK PDVDFIEGLSPAVSIDQKSTNRNPRSTVGTITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVL AMDEGLRFQVLAPVVRTRKGEFVDLFDKLNSQGYSRVRVDGVVHPLTDPPKLKKQEKHDIEVVVDRLTVK ATAKQRLTDSVETALNLADGIVVLEFVDREDDHPHREQRFSEKLACPNGHPLAVDDLEPRSFSFNSPYGA CPECTGLGIRKEVDPDLVVPDPDLTLAEGAIAPWSMGHTAEYFTRMLSGLGDQLGFDVNTPWKKLPAKAR RAILEGCDEQVHVRYKNRYGRTRSYYADFEGVMAFLQRRMEQTDSEQMKERLEGFMRDVPCPECDGTRLK PEILAVTMTAGNFGAKSIAEVAELSIADCAEFLNALTLGTREAAIAGQVLKEIQSRLGFLLDVGLDYLSL SRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIDTLVRLRDLGNTLIVVEHDLDT IAHADWVVDIGPAAGEHGGQIVHSGTYEDLLRNPNSITGAYLSGKEEIEVPDMRRVVDRKRQLTVVGARE HNLREIDVAFPLGVLTSVTGVSGSGKSTLVNDILASVLANKLNGARLVPGRHTRVNGLDHLDKLVRVDQS PIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACSGDGTIKIEMNFLPDVYV PCEVCQGARYNRETLEVHYKGKTIAEVLDMSIEEAAEFFAPISSIHRYLKTLVDVGLGYVRLGQPAPTLS GGEAQRVKLASELQKRSTGRTIYILDEPTTGLHFEDIRKLLTVINGLVDKGNTVIVIEHNLDVIKTSDWV VDMGPEGGSGGGTVVATGTPEDVAANPDSYTGHFLAETLGVARPKPKSRRRSKVSA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_3339 | uvrA | - | 100% (967) | excinuclease ABC subunit A |
M. vanbaalenii PYR-1 | Mvan_3006 | - | e-115 | 36.72% (768) | ABC transporter-related protein |
M. vanbaalenii PYR-1 | Mvan_1546 | - | 3e-10 | 32.12% (137) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1664 | uvrA | 0.0 | 88.27% (972) | excinuclease ABC subunit A |
M. gilvum PYR-GCK | Mflv_3548 | uvrA | 0.0 | 96.90% (967) | excinuclease ABC subunit A |
M. tuberculosis H37Rv | Rv1638 | uvrA | 0.0 | 88.27% (972) | excinuclease ABC subunit A |
M. leprae Br4923 | MLBr_01392 | uvrA | 0.0 | 87.00% (969) | excinuclease ABC subunit A |
M. abscessus ATCC 19977 | MAB_2315 | uvrA | 0.0 | 86.76% (967) | excinuclease ABC subunit A |
M. marinum M | MMAR_2443 | uvrA | 0.0 | 89.39% (971) | excinuclease ABC (subunit A-DNA-binding ATPase) UvrA |
M. avium 104 | MAV_3135 | uvrA | 0.0 | 89.76% (967) | excinuclease ABC subunit A |
M. smegmatis MC2 155 | MSMEG_3808 | uvrA | 0.0 | 93.49% (967) | excinuclease ABC subunit A |
M. thermoresistible (build 8) | TH_1581 | uvrA | 0.0 | 92.14% (967) | excinuclease ABC, A subunit |
M. ulcerans Agy99 | MUL_1622 | uvrA | 0.0 | 89.08% (971) | excinuclease ABC subunit A |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_3339|M.vanbaalenii_PYR-1 MADRLVVKGAREHNLRGVDLDLPRDAMIVFTGLSGSGKSSLAFDTIFAEG Mflv_3548|M.gilvum_PYR-GCK MADRLVVKGAREHNLRGVDLDLPRDAMIVFTGLSGSGKSSLAFDTIFAEG MSMEG_3808|M.smegmatis_MC2_155 MADRLVVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG TH_1581|M.thermoresistible__bu LADRLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG Mb1664|M.bovis_AF2122/97 MADRLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG Rv1638|M.tuberculosis_H37Rv MADRLIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG MMAR_2443|M.marinum_M MADRLIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG MUL_1622|M.ulcerans_Agy99 MADRLIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG MLBr_01392|M.leprae_Br4923 MADRLIVKGAREHNLRSVDLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEG MAV_3135|M.avium_104 MADRLIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEG MAB_2315|M.abscessus_ATCC_1997 MADRLIVRGAREHNLRGIDLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEG :****:*:********.:*******::*********************** Mvan_3339|M.vanbaalenii_PYR-1 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG Mflv_3548|M.gilvum_PYR-GCK QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG MSMEG_3808|M.smegmatis_MC2_155 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG TH_1581|M.thermoresistible__bu QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG Mb1664|M.bovis_AF2122/97 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG Rv1638|M.tuberculosis_H37Rv QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG MMAR_2443|M.marinum_M QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG MUL_1622|M.ulcerans_Agy99 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG MLBr_01392|M.leprae_Br4923 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG MAV_3135|M.avium_104 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG MAB_2315|M.abscessus_ATCC_1997 QRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKSTNRNPRSTVG ************************************************** Mvan_3339|M.vanbaalenii_PYR-1 TITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVLAMDEGLRFQ Mflv_3548|M.gilvum_PYR-GCK TITEVYDYLRLLYARAGTPHCPVCGERIAKQTPQQIVDQVLAMDEGLRFQ MSMEG_3808|M.smegmatis_MC2_155 TITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVLAMDEGLRFQ TH_1581|M.thermoresistible__bu TITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVLAMDEGLRFQ Mb1664|M.bovis_AF2122/97 TITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVLAMPEGTRFL Rv1638|M.tuberculosis_H37Rv TITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVLAMPEGTRFL MMAR_2443|M.marinum_M TITEVYDYLRLLYARAGTPHCPTCGERIARQTPQQIVDQVLAMAEGTRFL MUL_1622|M.ulcerans_Agy99 TITEVYDYLRLLYARAGTPHCPTCGERIARQTPQQIVDQVLAMAEGTRFL MLBr_01392|M.leprae_Br4923 TITEVYDYLRLLYARAGTPHCPICGEQISRQTPQQIVDQVLVLPEGTRFL MAV_3135|M.avium_104 TITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVLAMPEGTRFL MAB_2315|M.abscessus_ATCC_1997 TITEVYDYLRLLYARAGTPHCPVCGEKIAKQTPQQIVDQVLDMEEGLRFQ ********************** ***::::*********** : ** ** Mvan_3339|M.vanbaalenii_PYR-1 VLAPVVRTRKGEFVDLFDKLNSQGYSRVRVDGVVHPLTDPPKLKKQEKHD Mflv_3548|M.gilvum_PYR-GCK VLAPVVRTRKGEFVDLFDKLNTQGYSRVRVDGVVYPLTDPPKLKKQEKHD MSMEG_3808|M.smegmatis_MC2_155 VLAPVVRTRKGEFVDLFEKLNSQGYSRVRVDGVVYPLTDPPKLKKQEKHD TH_1581|M.thermoresistible__bu VLAPVVRTRKGEFVDLFDKLNSQGYSRVRVDGVVYPLTDPPKLKKQEKHD Mb1664|M.bovis_AF2122/97 VLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHD Rv1638|M.tuberculosis_H37Rv VLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHD MMAR_2443|M.marinum_M VLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHD MUL_1622|M.ulcerans_Agy99 VLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHD MLBr_01392|M.leprae_Br4923 VLAPVVRTRKGEFADLFDKLNAQGYSRVRVDDVVYPLSDPPKLKKQEKHD MAV_3135|M.avium_104 VLAPVVRTRKGEFADLFEKLNAQGYSRVRVDGVVHPLTDPPKLKKQEKHD MAB_2315|M.abscessus_ATCC_1997 VLAPVVRTRKGEFVDLFEQLNSQGYSRIRVDGVVHSLTDPPKLKKQEKHD *************.***::**:*****:***.**:.*:************ Mvan_3339|M.vanbaalenii_PYR-1 IEVVVDRLTVKATAKQRLTDSVETALNLADGIVVLEFVD-REDDHPHREQ Mflv_3548|M.gilvum_PYR-GCK IEVVVDRLTVKASSKQRLTDSIETALNLADGIVVLEFVD-REDDHPHREQ MSMEG_3808|M.smegmatis_MC2_155 IEVVVDRLTVKASAKQRLTDSIETALNLADGIVVLEFVD-REDDHPHREQ TH_1581|M.thermoresistible__bu IEVVVDRLTVKPSAKQRLTDSIETALNLADGIVVLDFVD-RDEDDPHREQ Mb1664|M.bovis_AF2122/97 IEVVVDRLTVKAAAKRRLTDSVETALNLADGIVVLEFVD-HELGAPHREQ Rv1638|M.tuberculosis_H37Rv IEVVVDRLTVKAAAKRRLTDSVETALNLADGIVVLEFVD-HELGAPHREQ MMAR_2443|M.marinum_M IEVVVDRLTVKAAAKQRLTDSVETALNLADGIVVLEFPDDHDEHDHPREQ MUL_1622|M.ulcerans_Agy99 IEVVVDRLTVKAAAKQRLTDSVETALNLADGIVVLEFPDDHDEHDHPREQ MLBr_01392|M.leprae_Br4923 IEVVVDRLTVKIAAKQRLTDSVETALNLADGIVVLEFPDDHDERGHPREQ MAV_3135|M.avium_104 IEVVVDRLTVKASAKQRLTDSVETALNLADGIVVLEFVD-HEHDAHNREQ MAB_2315|M.abscessus_ATCC_1997 IEVVIDRLSVKASSKQRLTDSVETALHLADGIVVLEFVD-ADEDSPQRER ****:***:** ::*:*****:****:********:* * : **: Mvan_3339|M.vanbaalenii_PYR-1 RFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECTGLGIRKEVDPDLV Mflv_3548|M.gilvum_PYR-GCK RFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECLGLGIRKEVDPDLV MSMEG_3808|M.smegmatis_MC2_155 RFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECTGLGIRKEVDPDLV TH_1581|M.thermoresistible__bu RFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECAGLGIRKEVDVDLV Mb1664|M.bovis_AF2122/97 RFSEKLACPNGHALAVDDLEPRSFSFNSPYGACPECSGLGIRKEVDPELV Rv1638|M.tuberculosis_H37Rv RFSEKLACPNGHALAVDDLEPRSFSFNSPYGACPECSGLGIRKEVDPELV MMAR_2443|M.marinum_M RFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECSGLGIRKEVDPDLV MUL_1622|M.ulcerans_Agy99 RFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECSGLGIRKEVDPDLV MLBr_01392|M.leprae_Br4923 CFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECVGLGIRKEIDSDLV MAV_3135|M.avium_104 RFSEKLACPNGHALAVDDLEPRSFSFNSPYGACPECSGLGIRKEVDPDLV MAB_2315|M.abscessus_ATCC_1997 RFSEKLACPNGHPLAVDDLEPRSFSFNSPYGACPECAGLGIKKEVDPDLV ***********.*********************** ****:**:* :** Mvan_3339|M.vanbaalenii_PYR-1 VPDPDLTLAEGAIAPWSMGHTAEYFTRMLSGLGDQLGFDVNTPWKKLPAK Mflv_3548|M.gilvum_PYR-GCK VPDPDLTLAEGAIAPWSMGNTADYFTRMLSGLGDQLGFDVNTPWKKLPAK MSMEG_3808|M.smegmatis_MC2_155 VPDPELTLAEGAVAPWSVGQSAEYFTRMLAGLGEEMGFDVNTPWKKLPAK TH_1581|M.thermoresistible__bu VPDPDLTLAEGAIAPWSMGQTAEYFTRMLAGLGEAMGFDVDTPWRKLPAK Mb1664|M.bovis_AF2122/97 VPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALGFDVDTPWRKLPAK Rv1638|M.tuberculosis_H37Rv VPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALGFDVDTPWRKLPAK MMAR_2443|M.marinum_M VPDPDRTLAEGAVAPWSTGHTAEYFTRMLAGLGDALGFDVDTPWRKLPAK MUL_1622|M.ulcerans_Agy99 VPDPDRTLAEGAVAPWSTGHTAEYFTRMLAGLGDALGFDVDTPWRKLPAK MLBr_01392|M.leprae_Br4923 VPDPDRTLAEGAVAPWSAGRTAEYFTRMMAGLGEKLGFDVDTPWRKLPAK MAV_3135|M.avium_104 VPDPERTLAEGAVAPWSTGHTAEYFTRMMAGLGDELGFDVDTPWRKLPAK MAB_2315|M.abscessus_ATCC_1997 VPDPDMTLAEGAIAPWSMGQNADYFVRLMAGLGDALGFDVDTPWKKLPAA ****: ***:**:**** *..*:**.*:::***: :****:***:**** Mvan_3339|M.vanbaalenii_PYR-1 ARRAILEGCDEQVHVRYKNRYGRTRSYYADFEGVMAFLQRRMEQTDSEQM Mflv_3548|M.gilvum_PYR-GCK ARKAILEGCDEQVHVRYKNRYGRTRSYYADFEGVMAFLQRRMEQTDSEQT MSMEG_3808|M.smegmatis_MC2_155 ARRAILEGCDHQVHVRYKNRYGRTRSYYADFEGVMAFLQRRMEQTDSEQM TH_1581|M.thermoresistible__bu VRKAILEGCDEQVHVRYKNRYGRVRSYYADFEGVMAYLHRRMEQTDSEQM Mb1664|M.bovis_AF2122/97 ARKAILEGADEQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMSQTESEQM Rv1638|M.tuberculosis_H37Rv ARKAILEGADEQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMSQTESEQM MMAR_2443|M.marinum_M ARKAILEGADEQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMAQTESEQM MUL_1622|M.ulcerans_Agy99 ARKAILEGADEQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMAQTESEQM MLBr_01392|M.leprae_Br4923 ARKAILEGSDHQVHVQYHNRYGRPRSYYVDFEGVLTFLQRKMEQTESEQM MAV_3135|M.avium_104 ARKAILEGSDHQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMAQTESEQM MAB_2315|M.abscessus_ATCC_1997 AKKAILDGSSEQVHVRYKNRYGRTRSYYAEFEGVLAFLQRRMEQTESEWA .::***:*...****:*:***** ****.:****:::*:*:* **:** Mvan_3339|M.vanbaalenii_PYR-1 KERLEGFMRDVPCPECDGTRLKPEILAVTMTA---GNFGAKSIAEVAELS Mflv_3548|M.gilvum_PYR-GCK KERLEGFMRDVPCPECDGTRLKPEILAVTMTA---GTFGAKSIAEVSELS MSMEG_3808|M.smegmatis_MC2_155 KERYEGFMRDIPCPECNGTRLKPEILAVTLSA---GDFGAKSIAQVAELS TH_1581|M.thermoresistible__bu KERLEGFMRDVPCPECGGTRLKPEILAVTLSA---GEFGEKSIAEVADLS Mb1664|M.bovis_AF2122/97 KERYEGFMRDVPCPVCAGTRLKPEILAVTLAGESKGEHGAKSIAEVCELS Rv1638|M.tuberculosis_H37Rv KERYEGFMRDVPCPVCAGTRLKPEILAVTLAGESKGEHGAKSIAEVCELS MMAR_2443|M.marinum_M KERYEGFMRDVPCPVCDGARLKPEILSVTLAA---GEQDAKSIAEVCELS MUL_1622|M.ulcerans_Agy99 KERYEGFMRDVPCPVCDGARLKPEILSVTLAA---GEQDAKSIAEVCELS MLBr_01392|M.leprae_Br4923 KERYEGFMRNIPCPVCQGTRLKPEILAVTLAA---GERGAKSIAEVCELS MAV_3135|M.avium_104 KERYEGFMRDVPCPVCEGTRLKPEILAVTLAA---GRHGKKSIAEVCELS MAB_2315|M.abscessus_ATCC_1997 KERYEGFMRDIPCPVCEGTRLKPEILSVTLTA---GEHGTKSIAEVCDLS *** *****::*** * *:*******:**::. * . ****:*.:** Mvan_3339|M.vanbaalenii_PYR-1 IADCAEFLNALTLGTREAAIAGQVLKEIQSRLGFLLDVGLDYLSLSRAAG Mflv_3548|M.gilvum_PYR-GCK IADCAAFLNALTLGTREAAIAGQVLKEIQSRLGFLLDVGLDYLSLSRAAG MSMEG_3808|M.smegmatis_MC2_155 IADCADFLNSLTLGPREQAIAGQVLKEIQSRLGFLLDVGLDYLSLSRAAA TH_1581|M.thermoresistible__bu IADCAEFLNALTLGPREQAIAGQVLKEIQSRLGFLLDVGLDYLSLSRAAA Mb1664|M.bovis_AF2122/97 IADCADFLNALTLGPREQAIAGQVLKEIRSRLGFLLDVGLEYLSLSRAAA Rv1638|M.tuberculosis_H37Rv IADCADFLNALTLGPREQAIAGQVLKEIRSRLGFLLDVGLEYLSLSRAAA MMAR_2443|M.marinum_M ISDCADFLNALTLGAREQAIAGQVLKEIQSRLGFLLDVGLEYLSLSRAAA MUL_1622|M.ulcerans_Agy99 ISDCADFLNALTLGAREQAIAGQVLKEIQSRLGFLLDVGLEYLSLSRAAA MLBr_01392|M.leprae_Br4923 IADCSAFLNALILGVREQAIAGQVLKEIQSRLGFLLDVGLEYLSLSRAAA MAV_3135|M.avium_104 ISDCAEFLNTLTLGPREQAIAGQVLKEIQSRLGFLLDVGLEYLSLSRAAA MAB_2315|M.abscessus_ATCC_1997 IADCAQFLGALTLGHREQAIAGQVLKEVQFRLGFLLDVGLQYLSLSRAAG *:**: **.:* ** ** *********:: **********:********. Mvan_3339|M.vanbaalenii_PYR-1 TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIDTLVRLR Mflv_3548|M.gilvum_PYR-GCK TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIDTLVRLR MSMEG_3808|M.smegmatis_MC2_155 TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIDTLVRLR TH_1581|M.thermoresistible__bu TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIDTLVRLR Mb1664|M.bovis_AF2122/97 TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLR Rv1638|M.tuberculosis_H37Rv TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLR MMAR_2443|M.marinum_M TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLR MUL_1622|M.ulcerans_Agy99 TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLR MLBr_01392|M.leprae_Br4923 TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLR MAV_3135|M.avium_104 TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLR MAB_2315|M.abscessus_ATCC_1997 TLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLR *******************************************:**.*** Mvan_3339|M.vanbaalenii_PYR-1 DLGNTLIVVEHDLDTIAHADWVVDIGPAAGEHGGQIVHSGTYEDLLRNPN Mflv_3548|M.gilvum_PYR-GCK DLGNTLIVVEHDLDTIAHADWVVDIGPAAGEHGGQIVHSGTYADLLTNPE MSMEG_3808|M.smegmatis_MC2_155 DLGNTLIVVEHDLDTIAHADWVVDIGPAAGEHGGQIVHSGTYDDLLRNPE TH_1581|M.thermoresistible__bu DLGNTLIVVEHDLDTIAHADWVVDIGPAAGEHGGRIVHSGPYADLLANPD Mb1664|M.bovis_AF2122/97 DLGNTLIVVEHDEDTIEHADWIVDIGPGAGEHGGRIVHSGPYDELLRNKD Rv1638|M.tuberculosis_H37Rv DLGNTLIVVEHDEDTIEHADWIVDIGPGAGEHGGRIVHSGPYDELLRNKD MMAR_2443|M.marinum_M DLGNTLIVVEHDEDTIEHADWVVDIGPGAGEHGGSIVHSGPYQELLRNQS MUL_1622|M.ulcerans_Agy99 DLGNTLIVVEHDEDTIEHADWVVDIGPGAGEHGGSIVHSGPYQELLRNQS MLBr_01392|M.leprae_Br4923 ALGNTLIVVEHDEDTIAHADWVVDIGPGAGEHGGQIVHNGTYRELLANKD MAV_3135|M.avium_104 DLGNTLIVVEHDEDTIAHADWIVDIGPRAGEHGGQIVHSGTYAELLANQD MAB_2315|M.abscessus_ATCC_1997 DLGNTLIVVEHDEDTIKHADWVVDIGPAAGEHGGQVVHSGTYAELLKNKN *********** *** ****:***** ****** :**.*.* :** * . Mvan_3339|M.vanbaalenii_PYR-1 SITGAYLSGKEEIEVPDMRRVVDRKRQLTVVGAREHNLREIDVAFPLGVL Mflv_3548|M.gilvum_PYR-GCK SITGAYLSGKEEIEVPTMRRVVDKKRQLTVVGAREHNLREIDVSFPLGVL MSMEG_3808|M.smegmatis_MC2_155 SLTGAYLSGKESIEVPAIRRPVDKKRQITVVGARENNLKEIDVAFPLGVL TH_1581|M.thermoresistible__bu SLTGEYLSGKKSIEVPAMRRPVDRKRQLTVVGARENNLRDIDVSFPLGVL Mb1664|M.bovis_AF2122/97 SITGAYLSGRESIEIPAIRRSVDPRRQLTVVGAREHNLRGIDVSFPLGVL Rv1638|M.tuberculosis_H37Rv SITGAYLSGRESIEIPAIRRSVDPRRQLTVVGAREHNLRGIDVSFPLGVL MMAR_2443|M.marinum_M SITGAFLSGREGIEIPTSRRSVDSRRQLTVVGAREHNLRGIDVAFPLGVL MUL_1622|M.ulcerans_Agy99 SITGAFLSGREGIEIPTSRRSIDSRRQLTVVGAREHNLRGLDVAFPLGVL MLBr_01392|M.leprae_Br4923 SITGAYLSGRESIATPTRRRSVDRKRELTVVGAREHNLRGIDVSFPLGVL MAV_3135|M.avium_104 SITGAYLSGKESIEMPAIRRPVDRRRQLTVVGAREHNLRGIDVSFPLGVL MAB_2315|M.abscessus_ATCC_1997 SVTGSYLSGAESIPLPLIRRVIDPKRQVTVVGAREHNLKDIDVSFPLGVL *:** :*** : * * ** :* :*::*******:**: :**:****** Mvan_3339|M.vanbaalenii_PYR-1 TSVTGVSGSGKSTLVNDILASVLANKLNGARLVPGRHTRVNGLDHLDKLV Mflv_3548|M.gilvum_PYR-GCK TSVTGVSGSGKSTLVNDILASVLANKLNGARLVPGRHTRINGLDHLDKLV MSMEG_3808|M.smegmatis_MC2_155 TSVTGVSGSGKSTMVNDILATVLANKLNGARLVPGRHTRVNGLDQLDKLV TH_1581|M.thermoresistible__bu TAVTGVSGSGKSTLVNDILAAALANKLNGARLVPGRHTRVNGLGEVDKLV Mb1664|M.bovis_AF2122/97 TSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRVTGLDYLDKLV Rv1638|M.tuberculosis_H37Rv TSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRVTGLDYLDKLV MMAR_2443|M.marinum_M TSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRITGLDHLDKLV MUL_1622|M.ulcerans_Agy99 TSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRITGLDHLDKLV MLBr_01392|M.leprae_Br4923 TSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRVTGLEHLDKLV MAV_3135|M.avium_104 TSVTGVSGSGKSTLVNDILATVLANRLNGARLVPGRHTRVTGLDHLDKLV MAB_2315|M.abscessus_ATCC_1997 TSVTGVSGSGKSTLVNDILATVLANKLNGARQVPGRHTRVTGLDKVDKLV *:***********:******:.***:***** *******:.** :**** Mvan_3339|M.vanbaalenii_PYR-1 RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK Mflv_3548|M.gilvum_PYR-GCK RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK MSMEG_3808|M.smegmatis_MC2_155 RVDQSPIGRTPRSNPATYTGVFDKIRSLFAATTEAKVRGYQPGRFSFNVK TH_1581|M.thermoresistible__bu RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK Mb1664|M.bovis_AF2122/97 RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK Rv1638|M.tuberculosis_H37Rv RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK MMAR_2443|M.marinum_M RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK MUL_1622|M.ulcerans_Agy99 RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK MLBr_01392|M.leprae_Br4923 RVDQSPIGRTPRSNPATYTGVFDKIRILFAATTEAKVRGYQPGRFSFNVK MAV_3135|M.avium_104 RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK MAB_2315|M.abscessus_ATCC_1997 RVDQSPIGRTPRSNPATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVK ************************** *********************** Mvan_3339|M.vanbaalenii_PYR-1 GGRCEACSGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTIA Mflv_3548|M.gilvum_PYR-GCK GGRCEACSGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTIA MSMEG_3808|M.smegmatis_MC2_155 GGRCEACSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKTIS TH_1581|M.thermoresistible__bu GGRCEACSGDGTLKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKTIA Mb1664|M.bovis_AF2122/97 GGRCEACTGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTVS Rv1638|M.tuberculosis_H37Rv GGRCEACTGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTVS MMAR_2443|M.marinum_M GGRCEACTGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTIS MUL_1622|M.ulcerans_Agy99 GGRCEACTGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYNGKTIS MLBr_01392|M.leprae_Br4923 GGRCEACTGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKAIS MAV_3135|M.avium_104 GGRCEACTGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKTIS MAB_2315|M.abscessus_ATCC_1997 GGRCEACTGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKTIA *******:****:*****************:*************:**::: Mvan_3339|M.vanbaalenii_PYR-1 EVLDMSIEEAAEFFAPISSIHRYLKTLVDVGLGYVRLGQPAPTLSGGEAQ Mflv_3548|M.gilvum_PYR-GCK EVLDMSIEEAAEFFAPISSIHRYLKTLVDVGLGYVRLGQPAPTLSGGEAQ MSMEG_3808|M.smegmatis_MC2_155 EVLDMSIEEATEFFEPISSIHRYLKTLVDVGLGYVRLGQPAPTLSGGEAQ TH_1581|M.thermoresistible__bu EVLDMSIEEAAEFFAPISSIHRYLQTLVDVGLGYVRLGQPAPTLSGGEAQ Mb1664|M.bovis_AF2122/97 EVLDMSIEEAAEFFEPIAGVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQ Rv1638|M.tuberculosis_H37Rv EVLDMSIEEAAEFFEPIAGVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQ MMAR_2443|M.marinum_M EVLDMSIEEAADFFEPISGIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQ MUL_1622|M.ulcerans_Agy99 EVLDMSIEEAADFFEPISGIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQ MLBr_01392|M.leprae_Br4923 EVLDMSIEEAAEFFEPIIGINRYLRTLVDVGLGYVRLGQPAPTLSGGEAQ MAV_3135|M.avium_104 EVLDMSIEEAAEFFEPITGIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQ MAB_2315|M.abscessus_ATCC_1997 QVLDMPIEEAAEFFEPITSIHRYLKTLVEVGLGYVRLGQPAPTLSGGEAQ :****.****::** ** .::***:***:********************* Mvan_3339|M.vanbaalenii_PYR-1 RVKLASELQKRSTGRTIYILDEPTTGLHFEDIRKLLTVINGLVDKGNTVI Mflv_3548|M.gilvum_PYR-GCK RVKLASELQKRSTGRTIYILDEPTTGLHFEDIRKLLTVINGLVDKGNTVI MSMEG_3808|M.smegmatis_MC2_155 RVKLAAELQKRSTGRTIYILDEPTTGLHFEDIRKLLKVINGLVDKGNTVI TH_1581|M.thermoresistible__bu RVKLASELQKRSTGRTVYILDEPTTGLHFEDIRKLLGVINGLVDKGNTVI Mb1664|M.bovis_AF2122/97 RVKLASELQKRSTGRTVYILDEPTTGLHFDDIRKLLNVINGLVDKGNTVI Rv1638|M.tuberculosis_H37Rv RVKLASELQKRSTGRTVYILDEPTTGLHFDDIRKLLNVINGLVDKGNTVI MMAR_2443|M.marinum_M RVKLASELQKRSTGRTIYILDEPTTGLHFDDIRKLLNVISGLVDKGNTVV MUL_1622|M.ulcerans_Agy99 RVKLASELQKRSTGRTIYILDEPTTGLHFDDIRKLLNVISGLVDKGNTVV MLBr_01392|M.leprae_Br4923 RVKLASELQKRSTGRTIYILDEPTTGLHFDDIRKLLNVINGLVDKDNTVI MAV_3135|M.avium_104 RVKLAAELQKRSTGRTIYILDEPTTGLHFDDIRKLLKVINGLVDKGNTVI MAB_2315|M.abscessus_ATCC_1997 RVKLAAELQKRSTGKTIYILDEPTTGLHFEDIRKLLTVINGLVDKGNTVI *****:********:*:************:****** **.*****.***: Mvan_3339|M.vanbaalenii_PYR-1 VIEHNLDVIKTSDWVVDMGPEGGSGGGTVVATGTPEDVAANPDSYTGHFL Mflv_3548|M.gilvum_PYR-GCK VIEHNLDVIKTSDWIIDMGPEGGSGGGTVVATGAPEDVAMNPDSYTGHFL MSMEG_3808|M.smegmatis_MC2_155 VIEHNLDVIKTSDWIIDMGPEGGAGGGTVVAQGTPEDVAANPDSYTGKFL TH_1581|M.thermoresistible__bu VIEHNLDVIKTADWIIDMGPEGGNGGGTVVAQGTPEDVAANPDSYTGQFL Mb1664|M.bovis_AF2122/97 VIEHNLDVIKTSDWIIDLGPEGGAGGGTVVAQGTPEDVAAVPASYTGKFL Rv1638|M.tuberculosis_H37Rv VIEHNLDVIKTSDWIIDLGPEGGAGGGTVVAQGTPEDVAAVPASYTGKFL MMAR_2443|M.marinum_M VIEHNLDVIKTSDWIIDMGPEGGAGGGTVVAQGAPEDIAAVPESYTGKFL MUL_1622|M.ulcerans_Agy99 VIEHNLDVIKTSDWIIDMGPEGGAGGGTVVAQGAPEDIAAVPESYTGKFL MLBr_01392|M.leprae_Br4923 VIEHNLDVIKTSDWIVDMGPEGGAQGGTVVAEGTPEDVAAVPESYTGKFL MAV_3135|M.avium_104 VIEHNLDVIKTSDWIVDMGPEGGAEGGTVVAQGTPEDVAAVPESYTGKFL MAB_2315|M.abscessus_ATCC_1997 VIEHNLDVIKTSDWIIDMGPEGGSGGGTVVAEGTPESVAQTAGSYTGEFL ***********:**::*:***** ****** *:**.:* . ****.** Mvan_3339|M.vanbaalenii_PYR-1 AETLGVA----------RPKPK------SRRRSKVSA-- Mflv_3548|M.gilvum_PYR-GCK AETLGMN----------RPKPK------ARARRKVSA-- MSMEG_3808|M.smegmatis_MC2_155 AELLDVP----------TPK---------RKRRKVSA-- TH_1581|M.thermoresistible__bu AEILDVP----------APT---------RKRRKVQVSA Mb1664|M.bovis_AF2122/97 AEVVGGGA------SAATSR--------SNRRRNVSA-- Rv1638|M.tuberculosis_H37Rv AEVVGGGA------SAATSR--------SNRRRNVSA-- MMAR_2443|M.marinum_M AEVLAARR------PSTTARR-------TNRRRKVSA-- MUL_1622|M.ulcerans_Agy99 AEVLAARR------PSTTARR-------TNRRRKVSA-- MLBr_01392|M.leprae_Br4923 AEVVGAG--------CAPART-------PRRRRTVTA-- MAV_3135|M.avium_104 AEVIGRGG------AAAGAPRR------SSRRRKATA-- MAB_2315|M.abscessus_ATCC_1997 VDLLPRPVRNGKAPAKAPAKSTGKTLAKARTRKVVTPV- .: : . * .