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M. thermoresistible (build 8) TH_4658 (-)

annotation: ABC transporter, ATP-binding protein
coordinates: 922848 - 925223
length: 792

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4658--100% (792)ABC transporter, ATP-binding protein
M. thermoresistible (build 8)TH_1581uvrAe-11739.03% (679) excinuclease ABC, A subunit
M. thermoresistible (build 8)TH_2785-4e-8733.14% (697) PUTATIVE putative Excinuclease ABC subunit A

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1664uvrA1e-11837.37% (752) excinuclease ABC subunit A
M. gilvum PYR-GCKMflv_0951-1e-13138.36% (855) ABC transporter related
M. tuberculosis H37RvRv1638uvrA1e-11837.37% (752) excinuclease ABC subunit A
M. leprae Br4923MLBr_01392uvrA1e-11237.98% (682) excinuclease ABC subunit A
M. abscessus ATCC 19977MAB_2315uvrA1e-11238.00% (679) excinuclease ABC subunit A
M. marinum MMMAR_2443uvrA1e-11438.53% (680) excinuclease ABC (subunit A-DNA-binding ATPase) UvrA
M. avium 104MAV_3135uvrA1e-11538.60% (684) excinuclease ABC subunit A
M. smegmatis MC2 155MSMEG_0211-0.082.23% (788) ABC transporter, ATP-binding protein
M. ulcerans Agy99MUL_1622uvrA1e-11438.38% (680) excinuclease ABC subunit A
M. vanbaalenii PYR-1Mvan_3006-0.080.48% (789) ABC transporter-related protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1664|M.bovis_AF2122/97            -----MADR----LIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSL
Rv1638|M.tuberculosis_H37Rv         -----MADR----LIVKGAREHNLRSVDLDLPRDALIVFTGLSGSGKSSL
MMAR_2443|M.marinum_M               -----MADR----LIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSL
MUL_1622|M.ulcerans_Agy99           -----MADR----LIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSL
MAV_3135|M.avium_104                -----MADR----LIVKGAREHNLRGVDLDLPRDALIVFTGLSGSGKSSL
MLBr_01392|M.leprae_Br4923          -----MADR----LIVKGAREHNLRSVDLDLPRDSLIVFTGLSGSGKSSL
MAB_2315|M.abscessus_ATCC_1997      -----MADR----LIVRGAREHNLRGIDLDLPRDSLIVFTGLSGSGKSSL
Mflv_0951|M.gilvum_PYR-GCK          -----MTGEPDPYIRVFASRVHNLKTVDVAAPRDSFVAFTGVSGSGKSSL
MSMEG_0211|M.smegmatis_MC2_155      ----MHPADSHDRIRVTGARENNLKDIDIELPKRRLTVFTGVSGSGKSSL
Mvan_3006|M.vanbaalenii_PYR-1       ---MPHAADSHDLIRVTGARENNLKNVSLELPKRRLTVFTGVSGSGKSSL
TH_4658|M.thermoresistible__bu      MTTDSHPADRHDLIRVLGARQNNLKNIDVEIPKRRLTVFTGVSGSGKSSL
                                          .      : * .:* :**: :.:  *:  : .***:********

Mb1664|M.bovis_AF2122/97            AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
Rv1638|M.tuberculosis_H37Rv         AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MMAR_2443|M.marinum_M               AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MUL_1622|M.ulcerans_Agy99           AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MAV_3135|M.avium_104                AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MLBr_01392|M.leprae_Br4923          AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
MAB_2315|M.abscessus_ATCC_1997      AFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVSIDQKST
Mflv_0951|M.gilvum_PYR-GCK          AFGTIYAEAQRRYFESVAPYARRLLLPQDAPKVDDITGLPPAVALQQRRG
MSMEG_0211|M.smegmatis_MC2_155      VFDTIAAESQRLINETYSAFIQGFMPNQARPEVDVLEGLTTAIIVDQQRM
Mvan_3006|M.vanbaalenii_PYR-1       VFDTIAAESQRLINETYSAFVQGFMPSLARPDVDVLEGLTTAIIVDQQRL
TH_4658|M.thermoresistible__bu      VFDTIAAESQRLINETYSAFIQGFMPTPARPDVDMLDGLTAAIIVDQNRL
                                    .*.** **.**   *: :.: : ::     *.** : **..*: ::*.  

Mb1664|M.bovis_AF2122/97            NRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVL
Rv1638|M.tuberculosis_H37Rv         NRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVL
MMAR_2443|M.marinum_M               NRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERIARQTPQQIVDQVL
MUL_1622|M.ulcerans_Agy99           NRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERIARQTPQQIVDQVL
MAV_3135|M.avium_104                NRNPRSTVGTITEVYDYLRLLYARAGTPHCPVCGERIARQTPQQIVDQVL
MLBr_01392|M.leprae_Br4923          NRNPRSTVGTITEVYDYLRLLYARAGTPHCPICGEQISRQTPQQIVDQVL
MAB_2315|M.abscessus_ATCC_1997      NRNPRSTVGTITEVYDYLRLLYARAGTPHCPVCGEKIAKQTPQQIVDQVL
Mflv_0951|M.gilvum_PYR-GCK          TATSRSTVGTVTTLSNLVRMLFSRAGT-----------------------
MSMEG_0211|M.smegmatis_MC2_155      GSDPRSTVGTVTDAGAMLRILFSRLGKPHVGS------------------
Mvan_3006|M.vanbaalenii_PYR-1       GADPRSTVGTATDTGAMLRILFSRLGQPHIGS------------------
TH_4658|M.thermoresistible__bu      GADPRSTVGTVTDTGALLRILYSRLGEPHIGS------------------
                                       .****** *     :*:*::* *                        

Mb1664|M.bovis_AF2122/97            AMPEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPP
Rv1638|M.tuberculosis_H37Rv         AMPEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPP
MMAR_2443|M.marinum_M               AMAEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPP
MUL_1622|M.ulcerans_Agy99           AMAEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPP
MAV_3135|M.avium_104                AMPEGTRFLVLAPVVRTRKGEFADLFEKLNAQGYSRVRVDGVVHPLTDPP
MLBr_01392|M.leprae_Br4923          VLPEGTRFLVLAPVVRTRKGEFADLFDKLNAQGYSRVRVDDVVYPLSDPP
MAB_2315|M.abscessus_ATCC_1997      DMEEGLRFQVLAPVVRTRKGEFVDLFEQLNSQGYSRIRVDGVVHSLTDPP
Mflv_0951|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0211|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_3006|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4658|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1664|M.bovis_AF2122/97            KLKKQEKHDIEVVVDRLTVKAAAKRRLTDSVETALNLADGIVVLEFVD-H
Rv1638|M.tuberculosis_H37Rv         KLKKQEKHDIEVVVDRLTVKAAAKRRLTDSVETALNLADGIVVLEFVD-H
MMAR_2443|M.marinum_M               KLKKQEKHDIEVVVDRLTVKAAAKQRLTDSVETALNLADGIVVLEFPDDH
MUL_1622|M.ulcerans_Agy99           KLKKQEKHDIEVVVDRLTVKAAAKQRLTDSVETALNLADGIVVLEFPDDH
MAV_3135|M.avium_104                KLKKQEKHDIEVVVDRLTVKASAKQRLTDSVETALNLADGIVVLEFVD-H
MLBr_01392|M.leprae_Br4923          KLKKQEKHDIEVVVDRLTVKIAAKQRLTDSVETALNLADGIVVLEFPDDH
MAB_2315|M.abscessus_ATCC_1997      KLKKQEKHDIEVVIDRLSVKASSKQRLTDSVETALHLADGIVVLEFVD-A
Mflv_0951|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0211|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_3006|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4658|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb1664|M.bovis_AF2122/97            ELGAPHREQRFSEKLACPNGHALAVDDLEPRSFS----FNSPYGACPECS
Rv1638|M.tuberculosis_H37Rv         ELGAPHREQRFSEKLACPNGHALAVDDLEPRSFS----FNSPYGACPECS
MMAR_2443|M.marinum_M               DEHDHPREQRFSEKLACPNGHPLAVDDLEPRSFS----FNSPYGACPECS
MUL_1622|M.ulcerans_Agy99           DEHDHPREQRFSEKLACPNGHPLAVDDLEPRSFS----FNSPYGACPECS
MAV_3135|M.avium_104                EHDAHNREQRFSEKLACPNGHALAVDDLEPRSFS----FNSPYGACPECS
MLBr_01392|M.leprae_Br4923          DERGHPREQCFSEKLACPNGHPLAVDDLEPRSFS----FNSPYGACPECV
MAB_2315|M.abscessus_ATCC_1997      DEDSPQRERRFSEKLACPNGHPLAVDDLEPRSFS----FNSPYGACPECA
Mflv_0951|M.gilvum_PYR-GCK          ----------------YPPG---ATERLDSDAFS----PNTTIGACPQCH
MSMEG_0211|M.smegmatis_MC2_155      -------PQAFSFNVASISGAGAVEFQKGGRTVKERRDFNIVGGMCPRCE
Mvan_3006|M.vanbaalenii_PYR-1       -------PQAFSFNVASMSGAGAVTFDRGGKTVKERRDFAIVGGMCPRCE
TH_4658|M.thermoresistible__bu      -------PQAFSFNVASISGAGAVTVERGGRTVKERREFEIVGGMCPRCE
                                                       *   .       :..         * **.* 

Mb1664|M.bovis_AF2122/97            GLGIRKEVDPELVVPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALG
Rv1638|M.tuberculosis_H37Rv         GLGIRKEVDPELVVPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALG
MMAR_2443|M.marinum_M               GLGIRKEVDPDLVVPDPDRTLAEGAVAPWSTGHTAEYFTRMLAGLGDALG
MUL_1622|M.ulcerans_Agy99           GLGIRKEVDPDLVVPDPDRTLAEGAVAPWSTGHTAEYFTRMLAGLGDALG
MAV_3135|M.avium_104                GLGIRKEVDPDLVVPDPERTLAEGAVAPWSTGHTAEYFTRMMAGLGDELG
MLBr_01392|M.leprae_Br4923          GLGIRKEIDSDLVVPDPDRTLAEGAVAPWSAGRTAEYFTRMMAGLGEKLG
MAB_2315|M.abscessus_ATCC_1997      GLGIKKEVDPDLVVPDPDMTLAEGAIAPWSMGQNADYFVRLMAGLGDALG
Mflv_0951|M.gilvum_PYR-GCK          GLGRIHEVTEETLVPDPSLSIRDGAVAAWPGAWQGQNLRDILI----TLG
MSMEG_0211|M.smegmatis_MC2_155      GRGSVNDIDLTALYDD-SKSLNEGALTIPGFSMDG-WYGRIFRGCG---F
Mvan_3006|M.vanbaalenii_PYR-1       GRGAINDIDLSALYDD-TKSLNDGALTIPGFSMEG-WYGRIFNGCG---F
TH_4658|M.thermoresistible__bu      GRGVINDIDRTALYDD-SKSLNEGALTIPGFSMDG-WYGRIFRGCG---F
                                    * *  :::    :  *   :: :**::    .  .     ::        

Mb1664|M.bovis_AF2122/97            FDVDTPWRKLPAKARKAILEGADEQVHVRYRNRYGRTRSYYAD--FEGVL
Rv1638|M.tuberculosis_H37Rv         FDVDTPWRKLPAKARKAILEGADEQVHVRYRNRYGRTRSYYAD--FEGVL
MMAR_2443|M.marinum_M               FDVDTPWRKLPAKARKAILEGADEQVHVRYRNRYGRTRSYYAD--FEGVL
MUL_1622|M.ulcerans_Agy99           FDVDTPWRKLPAKARKAILEGADEQVHVRYRNRYGRTRSYYAD--FEGVL
MAV_3135|M.avium_104                FDVDTPWRKLPAKARKAILEGSDHQVHVRYRNRYGRTRSYYAD--FEGVL
MLBr_01392|M.leprae_Br4923          FDVDTPWRKLPAKARKAILEGSDHQVHVQYHNRYGRPRSYYVD--FEGVL
MAB_2315|M.abscessus_ATCC_1997      FDVDTPWKKLPAAAKKAILDGSSEQVHVRYKNRYGRTRSYYAE--FEGVL
Mflv_0951|M.gilvum_PYR-GCK          YDIDKPWRKLTKRQRDWVLFTEDQPTVEIDPSRHPVTADYYYNGTFSSAE
MSMEG_0211|M.smegmatis_MC2_155      FDPDKPIKKFTKKELDALLYKDATRLKIDGTN------LTYLG-LIPQIQ
Mvan_3006|M.vanbaalenii_PYR-1       FDPDKPIRDFTAKELDALLHKEATKLKIDGVN------LTYLG-LIPQIK
TH_4658|M.thermoresistible__bu      FDPDKPIREFTRKELDALLYKEPTKLKIDGVN------LTYMG-LIPQIH
                                    :* *.* :.:.    . :*            .        *    :    

Mb1664|M.bovis_AF2122/97            AFLQRKMSQTESEQMKERYEGFMRDVPCPVCAGTRLKPEILAVTLAGESK
Rv1638|M.tuberculosis_H37Rv         AFLQRKMSQTESEQMKERYEGFMRDVPCPVCAGTRLKPEILAVTLAGESK
MMAR_2443|M.marinum_M               AFLQRKMAQTESEQMKERYEGFMRDVPCPVCDGARLKPEILSVTLAA---
MUL_1622|M.ulcerans_Agy99           AFLQRKMAQTESEQMKERYEGFMRDVPCPVCDGARLKPEILSVTLAA---
MAV_3135|M.avium_104                AFLQRKMAQTESEQMKERYEGFMRDVPCPVCEGTRLKPEILAVTLAA---
MLBr_01392|M.leprae_Br4923          TFLQRKMEQTESEQMKERYEGFMRNIPCPVCQGTRLKPEILAVTLAA---
MAB_2315|M.abscessus_ATCC_1997      AFLQRRMEQTESEWAKERYEGFMRDIPCPVCEGTRLKPEILSVTLTA---
Mflv_0951|M.gilvum_PYR-GCK          RHVRHTLANSQSAAMRRRVLQYVHSTDCPVCGGSGLRAEALAVTFAGRTI
MSMEG_0211|M.smegmatis_MC2_155      KSFLSKDVEAMQPHIRAFVERAVTFTTCPECDGTRLSETARSSKIDG---
Mvan_3006|M.vanbaalenii_PYR-1       KSFLAKDVEAMQPHIRAFVERAVTFTTCPDCDGTRLSETARSSKING---
TH_4658|M.thermoresistible__bu      KSFLSKDVEAMQPHIRAFVERAVTFTTCPDCDGTRLSERARSSKING---
                                      .     :: .   :      :    ** * *: *     : .: .   

Mb1664|M.bovis_AF2122/97            GEHGAKSIAEVCELSIADCADFLNALTLGPREQ----AIAGQVLKEIRSR
Rv1638|M.tuberculosis_H37Rv         GEHGAKSIAEVCELSIADCADFLNALTLGPREQ----AIAGQVLKEIRSR
MMAR_2443|M.marinum_M               GEQDAKSIAEVCELSISDCADFLNALTLGAREQ----AIAGQVLKEIQSR
MUL_1622|M.ulcerans_Agy99           GEQDAKSIAEVCELSISDCADFLNALTLGAREQ----AIAGQVLKEIQSR
MAV_3135|M.avium_104                GRHGKKSIAEVCELSISDCAEFLNTLTLGPREQ----AIAGQVLKEIQSR
MLBr_01392|M.leprae_Br4923          GERGAKSIAEVCELSIADCSAFLNALILGVREQ----AIAGQVLKEIQSR
MAB_2315|M.abscessus_ATCC_1997      GEHGTKSIAEVCDLSIADCAQFLGALTLGHREQ----AIAGQVLKEVQFR
Mflv_0951|M.gilvum_PYR-GCK          AELVALPLTTLAEVLEPAATRTEFAAAYESTESGEFTEVATMIAADLVAR
MSMEG_0211|M.smegmatis_MC2_155      -----VNIADASAMQITDLATWLAGLEKKATAKS-----VAPLLTALRHT
Mvan_3006|M.vanbaalenii_PYR-1       -----VSIADVSAMQITDLAQWIDGVSETTGIEG-----VAPLLTALRHT
TH_4658|M.thermoresistible__bu      -----RNIAEVSAWQISDLIDWVDDLRD----DS-----VAPLLGSLRHT
                                           ::  .    .               .      .  :   :   

Mb1664|M.bovis_AF2122/97            LGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPS
Rv1638|M.tuberculosis_H37Rv         LGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPS
MMAR_2443|M.marinum_M               LGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPS
MUL_1622|M.ulcerans_Agy99           LGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPS
MAV_3135|M.avium_104                LGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPS
MLBr_01392|M.leprae_Br4923          LGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVLYVLDEPS
MAB_2315|M.abscessus_ATCC_1997      LGFLLDVGLQYLSLSRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPS
Mflv_0951|M.gilvum_PYR-GCK          IGVLVDLGLGYLSLHRRTPTVSPGELQRLRLATQLRAGLFGVLYVLDEPS
MSMEG_0211|M.smegmatis_MC2_155      LDSFVEIGLGYLSLARPAGTLSGGEAQRVKMIRHLGSALTDVTYVFDEPT
Mvan_3006|M.vanbaalenii_PYR-1       LDSFVEIGLGYLSLDRPAGTLSGGEAQRVKMIRHLGSALTDVTYVFDEPT
TH_4658|M.thermoresistible__bu      LRSFVDIGLGYLSLDRPAGTLSGGEAQRVKMVRHLGSPLTDVTYVFDEPT
                                    :  ::::** **** * : *:* ** **:::  :: : * .* **:***:

Mb1664|M.bovis_AF2122/97            IGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWIVDIGPGAGE
Rv1638|M.tuberculosis_H37Rv         IGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWIVDIGPGAGE
MMAR_2443|M.marinum_M               IGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWVVDIGPGAGE
MUL_1622|M.ulcerans_Agy99           IGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIEHADWVVDIGPGAGE
MAV_3135|M.avium_104                IGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIAHADWIVDIGPRAGE
MLBr_01392|M.leprae_Br4923          IGLHQRDNRRLIETLTRLRALGNTLIVVEHDEDTIAHADWVVDIGPGAGE
MAB_2315|M.abscessus_ATCC_1997      IGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIKHADWVVDIGPAAGE
Mflv_0951|M.gilvum_PYR-GCK          AGLHPADAEPLLEVLDRLRRAGNSLFVVEHDMDVVRRADWVVDVGPGAGE
MSMEG_0211|M.smegmatis_MC2_155      IGLHPHDIARMNTLLLQLRDKGNTVLVVEHKPETIAIADHVVDLGPGAGT
Mvan_3006|M.vanbaalenii_PYR-1       IGLHPHDIDRMNTLLVQLRDKGNTVLVVEHKPETIAIADHVVDLGPGAGT
TH_4658|M.thermoresistible__bu      IGLHPHDIDRMNQLLLRLRDKGNTVLVVEHKPEVIAIADHIVDLGPGAGA
                                     ***  *   :   * :**  **:::****. :.:  ** :**:** ** 

Mb1664|M.bovis_AF2122/97            HGGRIVHSGPYDELLRNKDSITGAYLSGRESIEIPAIRRSVDPRRQLTVV
Rv1638|M.tuberculosis_H37Rv         HGGRIVHSGPYDELLRNKDSITGAYLSGRESIEIPAIRRSVDPRRQLTVV
MMAR_2443|M.marinum_M               HGGSIVHSGPYQELLRNQSSITGAFLSGREGIEIPTSRRSVDSRRQLTVV
MUL_1622|M.ulcerans_Agy99           HGGSIVHSGPYQELLRNQSSITGAFLSGREGIEIPTSRRSIDSRRQLTVV
MAV_3135|M.avium_104                HGGQIVHSGTYAELLANQDSITGAYLSGKESIEMPAIRRPVDRRRQLTVV
MLBr_01392|M.leprae_Br4923          HGGQIVHNGTYRELLANKDSITGAYLSGRESIATPTRRRSVDRKRELTVV
MAB_2315|M.abscessus_ATCC_1997      HGGQVVHSGTYAELLKNKNSVTGSYLSGAESIPLPLIRRVIDPKRQVTVV
Mflv_0951|M.gilvum_PYR-GCK          LGGDVLYSGPVAGLANVDASVTRRFLFAEEARPARAPRTPASVMR---LR
MSMEG_0211|M.smegmatis_MC2_155      AGGEVVFQGTVDGLRAS-DTVTGRHLGYRAALKDSVR----EPDGALEVR
Mvan_3006|M.vanbaalenii_PYR-1       AGGDVVFEGTVDGLRRS-DTLTGRHLDDRTSLKQSFR----KAHGALKIR
TH_4658|M.thermoresistible__bu      EGGEVVFAGSLDGLRAA-ATLTGRHLDDRAALKKKVR----TPTGVLPVR
                                     ** ::. *.   *     ::*  .*    .                 : 

Mb1664|M.bovis_AF2122/97            GAREHNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGAR
Rv1638|M.tuberculosis_H37Rv         GAREHNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGAR
MMAR_2443|M.marinum_M               GAREHNLRGIDVAFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGAR
MUL_1622|M.ulcerans_Agy99           GAREHNLRGLDVAFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGAR
MAV_3135|M.avium_104                GAREHNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILATVLANRLNGAR
MLBr_01392|M.leprae_Br4923          GAREHNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGAR
MAB_2315|M.abscessus_ATCC_1997      GAREHNLKDIDVSFPLGVLTSVTGVSGSGKSTLVNDILATVLANKLNGAR
Mflv_0951|M.gilvum_PYR-GCK          GITFHNLVGVDVDIPLGSFVAVTGVSGSGKSTLVCKVLGDVMARQLGRSP
MSMEG_0211|M.smegmatis_MC2_155      GANTNNLHDVDVDIPLGVLVVITGVAGSGKSSLIDGSVAGR---------
Mvan_3006|M.vanbaalenii_PYR-1       GADIHNLQNVDVDIPLGVLVVVTGVAGSGKSSLIDGSVAGR---------
TH_4658|M.thermoresistible__bu      DAHTNNLQHIDVDIPLGVLVVLTGVAGSGKSSLIDGSVAGR---------
                                    .   :**  :** :*** :. :***:*****:*:   :.           

Mb1664|M.bovis_AF2122/97            QVPGRHTR-----------------VTGLDYLDKLVRVDQSPIGRTPRSN
Rv1638|M.tuberculosis_H37Rv         QVPGRHTR-----------------VTGLDYLDKLVRVDQSPIGRTPRSN
MMAR_2443|M.marinum_M               QVPGRHTR-----------------ITGLDHLDKLVRVDQSPIGRTPRSN
MUL_1622|M.ulcerans_Agy99           QVPGRHTR-----------------ITGLDHLDKLVRVDQSPIGRTPRSN
MAV_3135|M.avium_104                LVPGRHTR-----------------VTGLDHLDKLVRVDQSPIGRTPRSN
MLBr_01392|M.leprae_Br4923          QVPGRHTR-----------------VTGLEHLDKLVRVDQSPIGRTPRSN
MAB_2315|M.abscessus_ATCC_1997      QVPGRHTR-----------------VTGLDKVDKLVRVDQSPIGRTPRSN
Mflv_0951|M.gilvum_PYR-GCK          EPAEDAADGDAELLDIDVDSSVGVAVEGAEIIDRLVTVDQRPIGRTPRSN
MSMEG_0211|M.smegmatis_MC2_155      --------------------------------EGVVLVDQSPIRGSRRSN
Mvan_3006|M.vanbaalenii_PYR-1       --------------------------------DGVVSVDQSPIRGSRRSN
TH_4658|M.thermoresistible__bu      --------------------------------DGVVTVDQSPLRGSRRSN
                                                                    : :* *** *:  : ***

Mb1664|M.bovis_AF2122/97            PATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIK
Rv1638|M.tuberculosis_H37Rv         PATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIK
MMAR_2443|M.marinum_M               PATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIK
MUL_1622|M.ulcerans_Agy99           PATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIK
MAV_3135|M.avium_104                PATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIK
MLBr_01392|M.leprae_Br4923          PATYTGVFDKIRILFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIK
MAB_2315|M.abscessus_ATCC_1997      PATYTGVFDKIRTLFAATTEAKVRGYQPGRFSFNVKGGRCEACTGDGTIK
Mflv_0951|M.gilvum_PYR-GCK          LATYTGLFDAVRKAFADTPEARRRGWSAGRFSFNVAEGRCATCQGEGFVA
MSMEG_0211|M.smegmatis_MC2_155      PATYTGLLEPIRKAFAKANGVK-----PALFSSNS-EGACPVCNGAGVIY
Mvan_3006|M.vanbaalenii_PYR-1       PATYTGALEPIRKAFAKANGVK-----PALFSSNS-EGACPTCNGVGVVF
TH_4658|M.thermoresistible__bu      PATYTGLLDPIRKAFAKANGVK-----PALFSSNS-EGACPLCNGAGIIY
                                     ***** :: :*  ** :  .:     .. ** *   * *  * * * : 

Mb1664|M.bovis_AF2122/97            IEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTVSEVLDMSIEEAAEFF
Rv1638|M.tuberculosis_H37Rv         IEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTVSEVLDMSIEEAAEFF
MMAR_2443|M.marinum_M               IEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKTISEVLDMSIEEAADFF
MUL_1622|M.ulcerans_Agy99           IEMNFLPDVYVPCEVCQGARYNRETLEVHYNGKTISEVLDMSIEEAADFF
MAV_3135|M.avium_104                IEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKTISEVLDMSIEEAAEFF
MLBr_01392|M.leprae_Br4923          IEMNFLPDVYVPCEVCQGARYNRETLEVHYKGKAISEVLDMSIEEAAEFF
MAB_2315|M.abscessus_ATCC_1997      IEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKTIAQVLDMPIEEAAEFF
Mflv_0951|M.gilvum_PYR-GCK          VELLFLPGTYATCPACGGARYSDETLEVTYRDRTIADVLAQTVDEAADFL
MSMEG_0211|M.smegmatis_MC2_155      TDLGVMATMESPCEECEGRRFQATVLEYTLAHRNIAEVLEMPVTEAVEFF
Mvan_3006|M.vanbaalenii_PYR-1       TDLGVMATVESLCEECEGRRFQAEVLGYTLGGRDIAEVLAMPVAEAAAFF
TH_4658|M.thermoresistible__bu      TELGVMATVETTCEECEGRRFQASVLAYELAGRNIADVLDMPVTEALDFF
                                     :: .:.     *  * * *:.  .*      : :::**  .: **  *:

Mb1664|M.bovis_AF2122/97            ----EPIAGVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQK
Rv1638|M.tuberculosis_H37Rv         ----EPIAGVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQK
MMAR_2443|M.marinum_M               ----EPISGIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQK
MUL_1622|M.ulcerans_Agy99           ----EPISGIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQK
MAV_3135|M.avium_104                ----EPITGIHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLAAELQK
MLBr_01392|M.leprae_Br4923          ----EPIIGINRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQK
MAB_2315|M.abscessus_ATCC_1997      ----EPITSIHRYLKTLVEVGLGYVRLGQPAPTLSGGEAQRVKLAAELQK
Mflv_0951|M.gilvum_PYR-GCK          ----TELPGAARSLTTLREVGLGYLRLGQPATELSGGEAQRIKLATELQR
MSMEG_0211|M.smegmatis_MC2_155      GAGEAKVPAAQKILERMADVGLGYLTLGQPLTTLSGGERQRLKLAAQMAD
Mvan_3006|M.vanbaalenii_PYR-1       SEGEAKVAAAQKILDRMADVGLGYLTLGQPLTTLSGGERQRLKLASRLSD
TH_4658|M.thermoresistible__bu      TDAHP-LPAARRILERLADVGLGYLGLGQSLTTLSGGERQRLKLAARLGD
                                          : .  : *  : :*****: ***. . ***** **:***:.:  

Mb1664|M.bovis_AF2122/97            RSTG-RTVYILDEPTTGLHFDDIRKLLNVINGLVDKGNTVIVIEHNLDVI
Rv1638|M.tuberculosis_H37Rv         RSTG-RTVYILDEPTTGLHFDDIRKLLNVINGLVDKGNTVIVIEHNLDVI
MMAR_2443|M.marinum_M               RSTG-RTIYILDEPTTGLHFDDIRKLLNVISGLVDKGNTVVVIEHNLDVI
MUL_1622|M.ulcerans_Agy99           RSTG-RTIYILDEPTTGLHFDDIRKLLNVISGLVDKGNTVVVIEHNLDVI
MAV_3135|M.avium_104                RSTG-RTIYILDEPTTGLHFDDIRKLLKVINGLVDKGNTVIVIEHNLDVI
MLBr_01392|M.leprae_Br4923          RSTG-RTIYILDEPTTGLHFDDIRKLLNVINGLVDKDNTVIVIEHNLDVI
MAB_2315|M.abscessus_ATCC_1997      RSTG-KTIYILDEPTTGLHFEDIRKLLTVINGLVDKGNTVIVIEHNLDVI
Mflv_0951|M.gilvum_PYR-GCK          AKRG-HTLYVLDEPTTGLHPADVELLERQLHRLVEAGNTVVVAEHDMAVV
MSMEG_0211|M.smegmatis_MC2_155      K----GNVYILDEPTTGLHLADVEQLLALLDRLVDSGKSVVVIEHHQAVM
Mvan_3006|M.vanbaalenii_PYR-1       KGADEGSVYILDEPTTGLHLADVDQLLGLLDRLVDSGRSVIVIEHHQAVM
TH_4658|M.thermoresistible__bu      KGADAATVYVLDEPTNGLHLADVEQLLALLDRLVDAGKSVLVIEHHQAVM
                                          .:*:*****.***  *:  *   :  **: ..:*:* **.  *:

Mb1664|M.bovis_AF2122/97            KTSDWIIDLGPEGGAGGGTVVAQGTPEDVAAVPASYTGKFLAEVVG----
Rv1638|M.tuberculosis_H37Rv         KTSDWIIDLGPEGGAGGGTVVAQGTPEDVAAVPASYTGKFLAEVVG----
MMAR_2443|M.marinum_M               KTSDWIIDMGPEGGAGGGTVVAQGAPEDIAAVPESYTGKFLAEVLA----
MUL_1622|M.ulcerans_Agy99           KTSDWIIDMGPEGGAGGGTVVAQGAPEDIAAVPESYTGKFLAEVLA----
MAV_3135|M.avium_104                KTSDWIVDMGPEGGAEGGTVVAQGTPEDVAAVPESYTGKFLAEVIGR---
MLBr_01392|M.leprae_Br4923          KTSDWIVDMGPEGGAQGGTVVAEGTPEDVAAVPESYTGKFLAEVVGA---
MAB_2315|M.abscessus_ATCC_1997      KTSDWIIDMGPEGGSGGGTVVAEGTPESVAQTAGSYTGEFLVDLLPRPVR
Mflv_0951|M.gilvum_PYR-GCK          AGADHVIDLGPGGGDDGGTVVAAGTPSVVAAHASSRTAPYLAVQLR----
MSMEG_0211|M.smegmatis_MC2_155      AHADWIIDLGPGAGHDGGRIVFEGTPADLVAARSTLTGRHLAEYVSS---
Mvan_3006|M.vanbaalenii_PYR-1       AHADWIIDLGPGAGHDGGRIVFEGTPRQLVDSATTLTAKHLADYVRT---
TH_4658|M.thermoresistible__bu      AHADWIIDLGPGAGHDGGHVVFEGTPADLVASRSTLTGRHLADYLRGG--
                                      :* ::*:** .*  ** :*  *:*  :.    : *. .*.  :     

Mb1664|M.bovis_AF2122/97            -GGASAATSR-SN-------RRRNVSA--
Rv1638|M.tuberculosis_H37Rv         -GGASAATSR-SN-------RRRNVSA--
MMAR_2443|M.marinum_M               -ARRPSTTARRTN-------RRRKVSA--
MUL_1622|M.ulcerans_Agy99           -ARRPSTTARRTN-------RRRKVSA--
MAV_3135|M.avium_104                -GGAAAGAPRRSS-------RRRKATA--
MLBr_01392|M.leprae_Br4923          -GCAPARTPR----------RRRTVTA--
MAB_2315|M.abscessus_ATCC_1997      NGKAPAKAPAKSTGKTLAKARTRKVVTPV
Mflv_0951|M.gilvum_PYR-GCK          -----------------------------
MSMEG_0211|M.smegmatis_MC2_155      -----------------------------
Mvan_3006|M.vanbaalenii_PYR-1       -----------------------------
TH_4658|M.thermoresistible__bu      -----------------------------