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SRVRTGEIRALSGLRIVAALWVVLFHFRPLLAEAAPGFNSALAPILNAGAQGVDLFFILSGFVLTWNYLD RMGESWSTRSTLRFLWLRLARVWPVYLVTMHLAAAFAIFTLYVGGHPLPPPVIESLNAMSWLKQVLLTQL WFQPYFDGSSWNGPAWSISAEWLAYLLFGGLVLIIFRIASATRARGLIWLAIAAALAPTLLLLAHGVFYT PWSWLPRIVMQFTAGALACAAVRKLVLTDRTQKAAGVASLLMGAAIVGGLYLLDANRPGDMLDAGGLVDV LFVPLVITLAIGAGTLPALLSTPVMVYLGHISFGLYMVHEIVHTAWNWAVLQFGIQLAPSWWAKFVVLGL ILFAGVAAALLYHVVEEPARRWMRRMVEPNRARPAQPTETAAGRLKPVAARAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2986 | - | - | 100% (404) | acyltransferase 3 |
| M. vanbaalenii PYR-1 | Mvan_4469 | - | 3e-21 | 25.82% (364) | acyltransferase 3 |
| M. vanbaalenii PYR-1 | Mvan_4285 | - | 3e-17 | 27.03% (333) | acyltransferase 3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0530 | - | 1e-152 | 67.00% (406) | membrane acyltransferase |
| M. gilvum PYR-GCK | Mflv_3267 | - | 0.0 | 88.12% (404) | acyltransferase 3 |
| M. tuberculosis H37Rv | Rv0517 | - | 1e-152 | 67.00% (406) | membrane acyltransferase |
| M. leprae Br4923 | MLBr_01101 | - | 3e-15 | 24.54% (326) | putative acyltransferase |
| M. abscessus ATCC 19977 | MAB_0401 | - | 1e-144 | 66.40% (375) | putative acyltransferase |
| M. marinum M | MMAR_0854 | - | 1e-153 | 66.91% (405) | membrane acyltransferase |
| M. avium 104 | MAV_4633 | - | 1e-140 | 63.41% (399) | putative acyltransferase, putative |
| M. smegmatis MC2 155 | MSMEG_3490 | - | 1e-148 | 64.30% (409) | putative membrane acyltransferase |
| M. thermoresistible (build 8) | TH_2230 | - | 5e-22 | 26.86% (350) | PROBABLE ACYLTRANSFERASE |
| M. ulcerans Agy99 | MUL_0606 | - | 1e-152 | 66.67% (405) | membrane acyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2986|M.vanbaalenii_PYR-1 ------------------------------------MSRVRTGEIRALSG
Mflv_3267|M.gilvum_PYR-GCK ------------------------------------MSRVRTGEIRALSG
MAB_0401|M.abscessus_ATCC_1997 -----------------------------------MRG----GEIKALTG
MSMEG_3490|M.smegmatis_MC2_155 -----------------------------------MRG----AEIKALTG
Mb0530|M.bovis_AF2122/97 -----MAGGMDQPPGQPRRRTRQQSS----DGKNGVRAAEITGEIRALTG
Rv0517|M.tuberculosis_H37Rv -----MAGGMDQPPGQPRRRTRQQSS----DGKNGVRAAEITGEIRALTG
MAV_4633|M.avium_104 -----------------------------------MRGGEIRGEIKALTG
MMAR_0854|M.marinum_M ------MRWLDPRVSRTSRRTRQRISRWRERGKTIVRSPMLRGEIKALTG
MUL_0606|M.ulcerans_Agy99 MPVGGLVRWLDPRVSRTSRRTRQRISRWRERGKTIVRSPMLQGEIKALTG
MLBr_01101|M.leprae_Br4923 -----------------MT------LSEERDAQSGLKQVSHVDRVASLTG
TH_2230|M.thermoresistible__bu -----------------MTVRRGGELTEPDVVQGGLESISRAERVASLTG
.: :*:*
Mvan_2986|M.vanbaalenii_PYR-1 LRIVAALWVVLFHFRPLLAEAAPGFNSALAPILNAGAQGVDLFFILSGFV
Mflv_3267|M.gilvum_PYR-GCK LRIVAALWVVLFHFRPMLAESAPGFTSALAPVLNAGAQGVDLFFILSGFV
MAB_0401|M.abscessus_ATCC_1997 LRIIAAFWVVLFHFRPLLEQAAPEFRTALNPILNCGAQGVDLFFILSGFV
MSMEG_3490|M.smegmatis_MC2_155 LRIVAAVWVVLFHFRPILYEAAPDFTETFAPVLDCGAQGVDLFFILSGFV
Mb0530|M.bovis_AF2122/97 LRIVAAVWVVLFHFRPMLGDASPGFRDALAPVLDCGAQGVDLFFILSGFV
Rv0517|M.tuberculosis_H37Rv LRIVAAVWVVLFHFRPMLGDASPGFRDALAPVLDCGAQGVDLFFILSGFV
MAV_4633|M.avium_104 LRIVAALWVVLFHFRPMLGDASPDLRDALAPVLNCGAQGVDLFFILSGFV
MMAR_0854|M.marinum_M LRIVAAVWVVLFHFRPMLADASPDFRENLAPVLNCGAQGVDLFFILSGFV
MUL_0606|M.ulcerans_Agy99 LRIVAAAWVVLFHFRPMLADASPDFRENLAPVLNCGAQGVDLFFILSGFV
MLBr_01101|M.leprae_Br4923 IRAVAALLIVGTHAAYTTGKYTHGYWGLVGARLEIGVP---IFFALSGFL
TH_2230|M.thermoresistible__bu IRAVAALLVVLTHAAYTTGRYPQGYLGLVYSRMEIGVP---IFFVLSGFL
:* :** :* * . . . :: *. :** ****:
Mvan_2986|M.vanbaalenii_PYR-1 LTWNYLDRMGESWSTRSTLRFLWLRLARVWPVYLVTMHLAAAFAIFTLYV
Mflv_3267|M.gilvum_PYR-GCK LAWNYLDRMGDSWSTRSTLRFLWLRLARVWPVYLVTMHLAAAFAVFTLYI
MAB_0401|M.abscessus_ATCC_1997 LTWNYLDRMGHRWSTRETLHFLWLRLARVWPVYLVTMHLAALWVIFTMHV
MSMEG_3490|M.smegmatis_MC2_155 LTWNYLDRMGPGWSTRATLHFLWLRLSRVWPVYLVTLHLAALWVIFTLNV
Mb0530|M.bovis_AF2122/97 LTWNYLDRMGRSWSVRANLHFLWLRLARVWPVYLVTLHLAAVWVIFTLHV
Rv0517|M.tuberculosis_H37Rv LTWNYLDRMGRSWSVRANLHFLWLRLARVWPVYLVTLHLAAVWVIFTLHV
MAV_4633|M.avium_104 LTYNYLDRMGRSFSTRATLHFLWLRLARVWPVYLVTLHLAALWVIFTLHV
MMAR_0854|M.marinum_M LTWNYLDRMGHSWSTRATLHFLWLRLARVWPVYLVTMHLAALLVIMTLHV
MUL_0606|M.ulcerans_Agy99 LTWNYLDRMGHSWSTRATLHFLWLRLARVWPVYLVTMHLAALLVIMTLHV
MLBr_01101|M.leprae_Br4923 LFSPWVKSAATGSPPPSVSRYAWHRVRRIMPAYVITVLFAYALYHFRAAG
TH_2230|M.thermoresistible__bu LFGPWVRAAAERRPAPSVKRYAWRRVRRIMPAYVVTVLAAYAVYHFRDAG
* :: . . :: * *: *: *.*::*: * :
Mvan_2986|M.vanbaalenii_PYR-1 GGHPLPPPVIESLNAMSWLKQVLLTQLWFQPYFDGSSWNGP--AWSISAE
Mflv_3267|M.gilvum_PYR-GCK GGFPLPPPVIESLNALSWLKQVFLVQLWFQPYFDGSSWNGP--AWSISAE
MAB_0401|M.abscessus_ATCC_1997 G--HVP-ERIDTFDATNYVRQLFMVQLWFRPYFDLSSWNGP--AWSISAE
MSMEG_3490|M.smegmatis_MC2_155 G--HVPVEDTSGYNAVSYLRQLFLVQLWFEPYFDGTSWDGP--AWSISAE
Mb0530|M.bovis_AF2122/97 G--HVPSPEAGQLTAISYVRQILLVQLWFQPYFDGSSWDGP--AWSISAE
Rv0517|M.tuberculosis_H37Rv G--HVPSPEAGQLTAISYVRQILLVQLWFQPYFDGSSWDGP--AWSISAE
MAV_4633|M.avium_104 G--HVPSPDAASLTAISYVRQILLVQLWFVPFFDDSSWDGP--AWSISAE
MMAR_0854|M.marinum_M G--HVPLPEVGQLTAVSYIRQVLMVQLWFQPFFDDSSWDGP--AWSISAE
MUL_0606|M.ulcerans_Agy99 G--HVPLPEVGQLTAVSYIRQVLMVQLWFQPFFDDSSWDGP--AWSISAE
MLBr_01101|M.leprae_Br4923 P--------NPGHSWMGLVRNLTLTQIYTDGYLGSYLHQGLTQMWSLAVE
TH_2230|M.thermoresistible__bu P--------NPGHTWEGLLRNLTHTQIYTDNYLYSYLHQGLTQMWSLAVE
. :::: .*:: :: :* **::.*
Mvan_2986|M.vanbaalenii_PYR-1 WLAYLLFGGLVLIIFRIASATRARG---LIWLAIAAALAPTLLLLAHGVF
Mflv_3267|M.gilvum_PYR-GCK WLAYLLFGGLVLIIFRIASATRARG---LMWLAIAAALAPTLLLLAHGVF
MAB_0401|M.abscessus_ATCC_1997 WLAYLLFGGLVLVIFRMAHATRARS---LMVLAVLASLPPVMLLLLTGQF
MSMEG_3490|M.smegmatis_MC2_155 WLAYLLFGALILVVFRIARATRARS---LVVLAVAASLPPVVLLMMTGHF
Mb0530|M.bovis_AF2122/97 WLAYLLFGLLILVIFRMKHATRARG---LMWLAFAASLPPVVLLLASGQF
Rv0517|M.tuberculosis_H37Rv WLAYLLFGLLILVIFRMKHATRARG---LMWLAFAASLPPVVLLLASGQF
MAV_4633|M.avium_104 WLAYVLFAGMVLVLLRMKQATRARS---LMVLAFAASLPPVVMLLASGHF
MMAR_0854|M.marinum_M WLAYLLFGALVLVIFRMTHATRARN---LMWLAFAASLPPVILLLASGQF
MUL_0606|M.ulcerans_Agy99 WLAYLLFGALVLVIFRMTHATRARN---LMWLAFAASLPPVILLLASGQF
MLBr_01101|M.leprae_Br4923 VAFYVALPLLAYLLLVLLCQRRWQPRLVLVVLAGMLLISPGWLILVHPDH
TH_2230|M.thermoresistible__bu VAFYAVLPLLAYLLLVVVCRRRWRPGLLLTGLAVLAAISPAWLYLVHTVD
* : : ::: : * : * ** :.* : :
Mvan_2986|M.vanbaalenii_PYR-1 YTP---WSWLPRIVMQFTAG-ALACAAVRKLVLTDRTQKAAGVASLLMGA
Mflv_3267|M.gilvum_PYR-GCK YTP---WSWLPRIIMQFTAG-ALACAAVRKLVLTESTRRAAGIASLLLGV
MAB_0401|M.abscessus_ATCC_1997 YTP---WSWLPRIVMQFTAG-ALACAAVSRLKLSHRSRHVAGYAALLIVA
MSMEG_3490|M.smegmatis_MC2_155 YTP---WSWLPRIVMQFTAG-ALACAAVRKLEPGDTARRTAGYLSVVLSI
Mb0530|M.bovis_AF2122/97 YTP---WSWLPRIVTQFAAG-ALACAAVRRLRPTDRARRIAGYLSVLVGV
Rv0517|M.tuberculosis_H37Rv YTP---WSWLPRIVTQFAAG-ALACAAVRRLRPTDRARRIAGYLSVLVGV
MAV_4633|M.avium_104 YTP---WSWLPRIVTQFTAG-ALACAAVRRLRLTDQGRRIAGYISLLLLA
MMAR_0854|M.marinum_M YTP---WSWLPRIVTQFVAG-ALAAAAVRRLRLTDRARRASGYLSVLLIA
MUL_0606|M.ulcerans_Agy99 YTP---WRWLPRIVTQFVAG-ALAAAAVRRLRLTDRARRASGYLSVLLIA
MLBr_01101|M.leprae_Br4923 WFPDGARLWLPTYLAWFLGGMILAVLQVMGVRCYAFGAIPLAIICYFIVS
TH_2230|M.thermoresistible__bu WLPDGARLWLPTYLIWFLGGMMLAALQPMGVRAYALVCIPLALICYFIVA
: * *** : * .* ** : . . .:
Mvan_2986|M.vanbaalenii_PYR-1 AIVGGLYLLDANRPGDML--DAGGLVDVLFVPLVITLAIG-AGTLPALLS
Mflv_3267|M.gilvum_PYR-GCK AIVGGLYALDTWPPGDML--DAGGLVDVLFVPLVIALSIG-AGTLPAFLS
MAB_0401|M.abscessus_ATCC_1997 SIVGALYFLDAHPISGVV--DSSGVVDVLFVPLVMALAVG-IGPLPTVLS
MSMEG_3490|M.smegmatis_MC2_155 AIIVGLFFFDAHPLNTVG--DAGGLVDILFVPLVVALAIG-TGSLPALLS
Mb0530|M.bovis_AF2122/97 AIVGILYLLHAHPLAGVE--DSGGVVDVLFVPLVISLAIG-VGSLPALLS
Rv0517|M.tuberculosis_H37Rv AIVGILYLLHAHPLAGVE--DSGGVVDVLFVPLVISLAIG-VGSLPALLS
MAV_4633|M.avium_104 AMVGVLYWFGAHPISGVVENDSGGVVDVLFVPLVISLAVG-LGSLPRVLS
MMAR_0854|M.marinum_M AIVGILYLVDAHPISGVV--DSGGVVDVLFVPLIVTLAVG-VGSLPRLLS
MUL_0606|M.ulcerans_Agy99 AIVGILYLVDAHPISGVV--DSGGVVDVLFVPLIVTLAVG-VGSLPRLLS
MLBr_01101|M.leprae_Br4923 TPIAGAPTTSPASLGEAL--IKVGFYAAIATLAVAPLTLGDLGWYSWLLS
TH_2230|M.thermoresistible__bu TPIGGEPTTSPNELWEAW--AKTGFYTVIATLMVAPLALGNKGWYSRVLG
: : . *. : . : .*::* * . .*.
Mvan_2986|M.vanbaalenii_PYR-1 TPVMVYLGHISFGLYMVHEIVHTAWNWAVLQFGIQLAPSWWAKFVVLGLI
Mflv_3267|M.gilvum_PYR-GCK TRVMVYLGHISFGLYMVHEIVHTMWNWAVLQFDIVLTPSWWAKLVVLGLI
MAB_0401|M.abscessus_ATCC_1997 TRIMVYGGQISFGLYMVHELVHVSWTWATKQFELSL-LDPGGGWIVIGLL
MSMEG_3490|M.smegmatis_MC2_155 TRVLVYGGQISFGLYMVHELVHTAWIWTVKQFELTMSPDLSGKATLLGLL
Mb0530|M.bovis_AF2122/97 TRLMVFGGQISFCLYMVHELVHTAWGWAVQQYELAL-QDQPWKWNVVGLL
Rv0517|M.tuberculosis_H37Rv TRLMVFGGQISFCLYMVHELVHTAWGWAVQQYELAL-QDQPWKWNVVGLL
MAV_4633|M.avium_104 ARAMVYGGKISFCLYMVHELVHTSWGWAVEQFELVT-QDNPWKWNVIGLL
MMAR_0854|M.marinum_M TRVMVYGGEISFCLYMVHELVHTAWGWAVLQFELTP-QDNPWKWNVIGLL
MUL_0606|M.ulcerans_Agy99 TRVMVYGGEISFCLYMVHEPVHTAWGWAVLQFELTP-QDNPWKWNVIGLL
MLBr_01101|M.leprae_Br4923 SRPMVWLGEISYEIFLIHLVTMEFAMVYVVQDHVYT-------GSMLNLI
TH_2230|M.thermoresistible__bu SRPMVFLGEISYEIFLIHLILMEVAMVEILRSPVYT-------GSMFWLF
: :*: *.**: ::::* : : :. *:
Mvan_2986|M.vanbaalenii_PYR-1 LFAGVAAALLYHVVEEPARRWMRRMVEPNRA--------RPAQPTETAAG
Mflv_3267|M.gilvum_PYR-GCK LFAGIAAAVLYHVVEEPARRWMRRMIEPERP--------RAAAASEPSTG
MAB_0401|M.abscessus_ATCC_1997 VLAVILSMALYHWVEEPGRRWMRRMIGVTKP-AITDHHASHNGHKARVP-
MSMEG_3490|M.smegmatis_MC2_155 AISVVAAMVLYHVVEEPARRWMRRMVDIRP-------VDPKNSHLHRVDA
Mb0530|M.bovis_AF2122/97 AIALGAAILLYHFVEEPDRRWMRRMVDVKAASARSEPGEPVGSTRYQIDD
Rv0517|M.tuberculosis_H37Rv AIALGAAILLYHFVEEPGRRWMRRMVDVKAASARSEPGEPVGSTRYQIDD
MAV_4633|M.avium_104 AIALAGAVVLYHGVEEPARRWMRKMVDVRAVSARSDPGEPANTKLHPIDR
MMAR_0854|M.marinum_M VIAVAASVLLYHFIEEPARRWMRRMVDVRAVTARIEPSEPVNGKRNQADG
MUL_0606|M.ulcerans_Agy99 VIAVAASVLLYHFIEEPARRWMRRMVDVRAVTARIEPSEPVNGKRNQADG
MLBr_01101|M.leprae_Br4923 VATLVLTIPLAWLLHRCTR--MRS--------------------------
TH_2230|M.thermoresistible__bu VWTMVLTIPLAWLLHRFTR--VRDQ-------------------------
: : * :.. * :*
Mvan_2986|M.vanbaalenii_PYR-1 RLKPVAARAG--------
Mflv_3267|M.gilvum_PYR-GCK RLQSVAARAG--------
MAB_0401|M.abscessus_ATCC_1997 ENLTEPEREPVVTGVTTR
MSMEG_3490|M.smegmatis_MC2_155 EHQGHSAAVPARAG----
Mb0530|M.bovis_AF2122/97 ALEGVSARAV--------
Rv0517|M.tuberculosis_H37Rv ALEGVSARAV--------
MAV_4633|M.avium_104 PLEAISARAV--------
MMAR_0854|M.marinum_M ALEGFSARAV--------
MUL_0606|M.ulcerans_Agy99 ALEGFSARAV--------
MLBr_01101|M.leprae_Br4923 ------------------
TH_2230|M.thermoresistible__bu ------------------