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VRWLDPRVSRTSRRTRQRISRWRERGKTIVRSPMLRGEIKALTGLRIVAAVWVVLFHFRPMLADASPDFR ENLAPVLNCGAQGVDLFFILSGFVLTWNYLDRMGHSWSTRATLHFLWLRLARVWPVYLVTMHLAALLVIM TLHVGHVPLPEVGQLTAVSYIRQVLMVQLWFQPFFDDSSWDGPAWSISAEWLAYLLFGALVLVIFRMTHA TRARNLMWLAFAASLPPVILLLASGQFYTPWSWLPRIVTQFVAGALAAAAVRRLRLTDRARRASGYLSVL LIAAIVGILYLVDAHPISGVVDSGGVVDVLFVPLIVTLAVGVGSLPRLLSTRVMVYGGEISFCLYMVHEL VHTAWGWAVLQFELTPQDNPWKWNVIGLLVIAVAASVLLYHFIEEPARRWMRRMVDVRAVTARIEPSEPV NGKRNQADGALEGFSARAV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_0854 | - | - | 100% (439) | membrane acyltransferase |
M. marinum M | MMAR_0312 | - | 2e-13 | 26.20% (439) | transmembrane acyltransferase |
M. marinum M | MMAR_4188 | - | 2e-12 | 24.17% (331) | integral membrane acyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0530 | - | 0.0 | 78.44% (436) | membrane acyltransferase |
M. gilvum PYR-GCK | Mflv_3267 | - | 1e-150 | 64.78% (406) | acyltransferase 3 |
M. tuberculosis H37Rv | Rv0517 | - | 0.0 | 78.44% (436) | membrane acyltransferase |
M. leprae Br4923 | MLBr_02670 | - | 2e-13 | 24.70% (417) | hypothetical protein MLBr_02670 |
M. abscessus ATCC 19977 | MAB_0401 | - | 1e-163 | 74.12% (371) | putative acyltransferase |
M. avium 104 | MAV_4633 | - | 0.0 | 78.64% (412) | putative acyltransferase, putative |
M. smegmatis MC2 155 | MSMEG_3490 | - | 1e-162 | 69.50% (400) | putative membrane acyltransferase |
M. thermoresistible (build 8) | TH_1720 | - | 8e-16 | 25.06% (387) | PROBABLE ACYLTRANSFERASE |
M. ulcerans Agy99 | MUL_0606 | - | 0.0 | 99.09% (439) | membrane acyltransferase |
M. vanbaalenii PYR-1 | Mvan_2986 | - | 1e-153 | 66.91% (405) | acyltransferase 3 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3267|M.gilvum_PYR-GCK ------------------------------------MSRVRTGEIRALSG Mvan_2986|M.vanbaalenii_PYR-1 ------------------------------------MSRVRTGEIRALSG MMAR_0854|M.marinum_M ------MRWLDPRVSRTSRRTRQRISRWRERGKTIVRSPMLRGEIKALTG MUL_0606|M.ulcerans_Agy99 MPVGGLVRWLDPRVSRTSRRTRQRISRWRERGKTIVRSPMLQGEIKALTG Mb0530|M.bovis_AF2122/97 -----MAGGMDQPPGQPRRRTRQQSS----DGKNGVRAAEITGEIRALTG Rv0517|M.tuberculosis_H37Rv -----MAGGMDQPPGQPRRRTRQQSS----DGKNGVRAAEITGEIRALTG MAV_4633|M.avium_104 -----------------------------------MRGGEIRGEIKALTG MAB_0401|M.abscessus_ATCC_1997 -----------------------------------MRG----GEIKALTG MSMEG_3490|M.smegmatis_MC2_155 -----------------------------------MRG----AEIKALTG TH_1720|M.thermoresistible__bu ----------------------VRPSPETDLDQGGLEQVSTVDRVAALTG MLBr_02670|M.leprae_Br4923 --------------------------MRRVGLLRIWNQPERRNGIPALDG : ** * Mflv_3267|M.gilvum_PYR-GCK LRIVAALWVVLFHFRPMLAESAPGFTSALAPVLNAGAQGVDLFFILSGFV Mvan_2986|M.vanbaalenii_PYR-1 LRIVAALWVVLFHFRPLLAEAAPGFNSALAPILNAGAQGVDLFFILSGFV MMAR_0854|M.marinum_M LRIVAAVWVVLFHFRPMLADASPDFRENLAPVLNCGAQGVDLFFILSGFV MUL_0606|M.ulcerans_Agy99 LRIVAAAWVVLFHFRPMLADASPDFRENLAPVLNCGAQGVDLFFILSGFV Mb0530|M.bovis_AF2122/97 LRIVAAVWVVLFHFRPMLGDASPGFRDALAPVLDCGAQGVDLFFILSGFV Rv0517|M.tuberculosis_H37Rv LRIVAAVWVVLFHFRPMLGDASPGFRDALAPVLDCGAQGVDLFFILSGFV MAV_4633|M.avium_104 LRIVAALWVVLFHFRPMLGDASPDLRDALAPVLNCGAQGVDLFFILSGFV MAB_0401|M.abscessus_ATCC_1997 LRIIAAFWVVLFHFRPLLEQAAPEFRTALNPILNCGAQGVDLFFILSGFV MSMEG_3490|M.smegmatis_MC2_155 LRIVAAVWVVLFHFRPILYEAAPDFTETFAPVLDCGAQGVDLFFILSGFV TH_1720|M.thermoresistible__bu VRAVAALSVMGTHAAYGTGTYNHGYVGLIFARMDIG---VAVFFVLSGFL MLBr_02670|M.leprae_Br4923 LRAIAVALVLTQHGG--------------IPGLSGGFIGVDLFFVLSGFL :* :*. *: * . :. * * :**:****: Mflv_3267|M.gilvum_PYR-GCK LAWNYLDRMGDSWSTRSTLRFLWLRLARVWPVYLVTMHLAA-AFAVFTLY Mvan_2986|M.vanbaalenii_PYR-1 LTWNYLDRMGESWSTRSTLRFLWLRLARVWPVYLVTMHLAA-AFAIFTLY MMAR_0854|M.marinum_M LTWNYLDRMGHSWSTRATLHFLWLRLARVWPVYLVTMHLAA-LLVIMTLH MUL_0606|M.ulcerans_Agy99 LTWNYLDRMGHSWSTRATLHFLWLRLARVWPVYLVTMHLAA-LLVIMTLH Mb0530|M.bovis_AF2122/97 LTWNYLDRMGRSWSVRANLHFLWLRLARVWPVYLVTLHLAA-VWVIFTLH Rv0517|M.tuberculosis_H37Rv LTWNYLDRMGRSWSVRANLHFLWLRLARVWPVYLVTLHLAA-VWVIFTLH MAV_4633|M.avium_104 LTYNYLDRMGRSFSTRATLHFLWLRLARVWPVYLVTLHLAA-LWVIFTLH MAB_0401|M.abscessus_ATCC_1997 LTWNYLDRMGHRWSTRETLHFLWLRLARVWPVYLVTMHLAA-LWVIFTMH MSMEG_3490|M.smegmatis_MC2_155 LTWNYLDRMGPGWSTRATLHFLWLRLSRVWPVYLVTLHLAA-LWVIFTLN TH_1720|M.thermoresistible__bu LFRPWVRAAADGTAAPSVRRYARNRVRRIMPAYVVTVLAAYGIYAVRELE MLBr_02670|M.leprae_Br4923 ITSLLLDELRHTG-RIDAINFWIRRACRLLPALVLMVLTVGIARELFPYQ : : .: * *: *. :: : . : Mflv_3267|M.gilvum_PYR-GCK IGGFPLPPPVIESLNALSWLKQVFLVQLWFQPYFDGSSWNGP--AWSISA Mvan_2986|M.vanbaalenii_PYR-1 VGGHPLPPPVIESLNAMSWLKQVLLTQLWFQPYFDGSSWNGP--AWSISA MMAR_0854|M.marinum_M VG--HVPLPEVGQLTAVSYIRQVLMVQLWFQPFFDDSSWDGP--AWSISA MUL_0606|M.ulcerans_Agy99 VG--HVPLPEVGQLTAVSYIRQVLMVQLWFQPFFDDSSWDGP--AWSISA Mb0530|M.bovis_AF2122/97 VG--HVPSPEAGQLTAISYVRQILLVQLWFQPYFDGSSWDGP--AWSISA Rv0517|M.tuberculosis_H37Rv VG--HVPSPEAGQLTAISYVRQILLVQLWFQPYFDGSSWDGP--AWSISA MAV_4633|M.avium_104 VG--HVPSPDAASLTAISYVRQILLVQLWFVPFFDDSSWDGP--AWSISA MAB_0401|M.abscessus_ATCC_1997 VG--HVP-ERIDTFDATNYVRQLFMVQLWFRPYFDLSSWNGP--AWSISA MSMEG_3490|M.smegmatis_MC2_155 VG--HVPVEDTSGYNAVSYLRQLFLVQLWFEPYFDGTSWDGP--AWSISA TH_1720|M.thermoresistible__bu PN---------PGHTWVGLLRNLTLTQIYSDDYLTAYAHQGLTQMWSLAV MLBr_02670|M.leprae_Br4923 ALT----NLRNDAIATFLWVANWRFVVHKADYFTQGTPPSPLQHAWSLGV : : :. : . . **:.. Mflv_3267|M.gilvum_PYR-GCK EWLAYLLFGGLVLIIFRIASATRARGLMWLAIAAALAPTLLLLAHGVFYT Mvan_2986|M.vanbaalenii_PYR-1 EWLAYLLFGGLVLIIFRIASATRARGLIWLAIAAALAPTLLLLAHGVFYT MMAR_0854|M.marinum_M EWLAYLLFGALVLVIFRMTHATRARNLMWLAFAASLPPVILLLASGQFYT MUL_0606|M.ulcerans_Agy99 EWLAYLLFGALVLVIFRMTHATRARNLMWLAFAASLPPVILLLASGQFYT Mb0530|M.bovis_AF2122/97 EWLAYLLFGLLILVIFRMKHATRARGLMWLAFAASLPPVVLLLASGQFYT Rv0517|M.tuberculosis_H37Rv EWLAYLLFGLLILVIFRMKHATRARGLMWLAFAASLPPVVLLLASGQFYT MAV_4633|M.avium_104 EWLAYVLFAGMVLVLLRMKQATRARSLMVLAFAASLPPVVMLLASGHFYT MAB_0401|M.abscessus_ATCC_1997 EWLAYLLFGGLVLVIFRMAHATRARSLMVLAVLASLPPVMLLLLTGQFYT MSMEG_3490|M.smegmatis_MC2_155 EWLAYLLFGALILVVFRIARATRARSLVVLAVAASLPPVVLLMMTGHFYT TH_1720|M.thermoresistible__bu EVAFYAALPVLAWLLLVVLARRRWRPVPLLTGLGVLAVVSPLWVVVLHRT MLBr_02670|M.leprae_Br4923 EEQYYLVWPLLLIAVTLLLAARARRRCRYATLGAVRLAVFVLASLGALAS * * : : : * : . . * : Mflv_3267|M.gilvum_PYR-GCK PWS------WLPRIIMQFTAG-----ALACAAVRKLVLTEST-------- Mvan_2986|M.vanbaalenii_PYR-1 PWS------WLPRIVMQFTAG-----ALACAAVRKLVLTDRT-------- MMAR_0854|M.marinum_M PWS------WLPRIVTQFVAG-----ALAAAAVRRLRLTDRA-------- MUL_0606|M.ulcerans_Agy99 PWR------WLPRIVTQFVAG-----ALAAAAVRRLRLTDRA-------- Mb0530|M.bovis_AF2122/97 PWS------WLPRIVTQFAAG-----ALACAAVRRLRPTDRA-------- Rv0517|M.tuberculosis_H37Rv PWS------WLPRIVTQFAAG-----ALACAAVRRLRPTDRA-------- MAV_4633|M.avium_104 PWS------WLPRIVTQFTAG-----ALACAAVRRLRLTDQG-------- MAB_0401|M.abscessus_ATCC_1997 PWS------WLPRIVMQFTAG-----ALACAAVSRLKLSHRS-------- MSMEG_3490|M.smegmatis_MC2_155 PWS------WLPRIVMQFTAG-----ALACAAVRKLEPGDTA-------- TH_1720|M.thermoresistible__bu DWLPLGAGFWLPHYLIWFVGGM----VLAVLQAQGVRAYAAA-------- MLBr_02670|M.leprae_Br4923 ATVAIARVCDVTRDRIYFGTDTRAQALLVGAAASALLVRDWPSLNRGWCL :.: * . *. . : Mflv_3267|M.gilvum_PYR-GCK --RRAAGIASLLLGVAIVGGLYALDTWPPGDML--DAGGLVDVLFVPLVI Mvan_2986|M.vanbaalenii_PYR-1 --QKAAGVASLLMGAAIVGGLYLLDANRPGDML--DAGGLVDVLFVPLVI MMAR_0854|M.marinum_M --RRASGYLSVLLIAAIVGILYLVDAHPISGVV--DSGGVVDVLFVPLIV MUL_0606|M.ulcerans_Agy99 --RRASGYLSVLLIAAIVGILYLVDAHPISGVV--DSGGVVDVLFVPLIV Mb0530|M.bovis_AF2122/97 --RRIAGYLSVLVGVAIVGILYLLHAHPLAGVE--DSGGVVDVLFVPLVI Rv0517|M.tuberculosis_H37Rv --RRIAGYLSVLVGVAIVGILYLLHAHPLAGVE--DSGGVVDVLFVPLVI MAV_4633|M.avium_104 --RRIAGYISLLLLAAMVGVLYWFGAHPISGVVENDSGGVVDVLFVPLVI MAB_0401|M.abscessus_ATCC_1997 --RHVAGYAALLIVASIVGALYFLDAHPISGVV--DSSGVVDVLFVPLVM MSMEG_3490|M.smegmatis_MC2_155 --RRTAGYLSVVLSIAIIVGLFFFDAHPLNTVG--DAGGLVDILFVPLVV TH_1720|M.thermoresistible__bu --TVPVAVAAYLIVATPIAGDTGAPVLNLGQDL--AKVMFYAVIATLVVA MLBr_02670|M.leprae_Br4923 IRTRWGQLIARFLPVLGLAGLAAATHYATGGAGDFRHGLLIGVAIAAVIV : .: : . : . :: Mflv_3267|M.gilvum_PYR-GCK ALSIG---AGTLPAFLSTRVMVYLGHISFGLYMVHEIVHTMWN------- Mvan_2986|M.vanbaalenii_PYR-1 TLAIG---AGTLPALLSTPVMVYLGHISFGLYMVHEIVHTAWN------- MMAR_0854|M.marinum_M TLAVG---VGSLPRLLSTRVMVYGGEISFCLYMVHELVHTAWG------- MUL_0606|M.ulcerans_Agy99 TLAVG---VGSLPRLLSTRVMVYGGEISFCLYMVHEPVHTAWG------- Mb0530|M.bovis_AF2122/97 SLAIG---VGSLPALLSTRLMVFGGQISFCLYMVHELVHTAWG------- Rv0517|M.tuberculosis_H37Rv SLAIG---VGSLPALLSTRLMVFGGQISFCLYMVHELVHTAWG------- MAV_4633|M.avium_104 SLAVG---LGSLPRVLSARAMVYGGKISFCLYMVHELVHTSWG------- MAB_0401|M.abscessus_ATCC_1997 ALAVG---IGPLPTVLSTRIMVYGGQISFGLYMVHELVHVSWT------- MSMEG_3490|M.smegmatis_MC2_155 ALAIG---TGSLPALLSTRVLVYGGQISFGLYMVHELVHTAWI------- TH_1720|M.thermoresistible__bu PPALGN--RGWYTRMLGSRPMVWLGEISYEIFLVHVIVMEIAM------- MLBr_02670|M.leprae_Br4923 IAPVALEQRGTVARLLALRPLVWLGTISYGIYLWHWPIFLALNGERTGWS .:. * . .*. :*: * **: ::: * : Mflv_3267|M.gilvum_PYR-GCK -------------------WAVLQFDIVLTPSWWAKLVVLGLILFAGIAA Mvan_2986|M.vanbaalenii_PYR-1 -------------------WAVLQFGIQLAPSWWAKFVVLGLILFAGVAA MMAR_0854|M.marinum_M -------------------WAVLQFELTP-QDNPWKWNVIGLLVIAVAAS MUL_0606|M.ulcerans_Agy99 -------------------WAVLQFELTP-QDNPWKWNVIGLLVIAVAAS Mb0530|M.bovis_AF2122/97 -------------------WAVQQYELAL-QDQPWKWNVVGLLAIALGAA Rv0517|M.tuberculosis_H37Rv -------------------WAVQQYELAL-QDQPWKWNVVGLLAIALGAA MAV_4633|M.avium_104 -------------------WAVEQFELVT-QDNPWKWNVIGLLAIALAGA MAB_0401|M.abscessus_ATCC_1997 -------------------WATKQFELSL-LDPGGGWIVIGLLVLAVILS MSMEG_3490|M.smegmatis_MC2_155 -------------------WTVKQFELTMSPDLSGKATLLGLLAISVVAA TH_1720|M.thermoresistible__bu -------------------VSVLRWPVYT-------GSVLGLFATTLALT MLBr_02670|M.leprae_Br4923 GVPLFASRCSATVAVAAVSWWLIEQPIRHWRPVRVPLLPLAAATVASAAA . : :. : : Mflv_3267|M.gilvum_PYR-GCK AVLYHVVEEPARRWMRRMIEPERP--------RAAAASEPSTGRLQSVAA Mvan_2986|M.vanbaalenii_PYR-1 ALLYHVVEEPARRWMRRMVEPNRA--------RPAQPTETAAGRLKPVAA MMAR_0854|M.marinum_M VLLYHFIEEPARRWMRRMVDVRAVTARIEPSEPVNGKRNQADGALEGFSA MUL_0606|M.ulcerans_Agy99 VLLYHFIEEPARRWMRRMVDVRAVTARIEPSEPVNGKRNQADGALEGFSA Mb0530|M.bovis_AF2122/97 ILLYHFVEEPDRRWMRRMVDVKAASARSEPGEPVGSTRYQIDDALEGVSA Rv0517|M.tuberculosis_H37Rv ILLYHFVEEPGRRWMRRMVDVKAASARSEPGEPVGSTRYQIDDALEGVSA MAV_4633|M.avium_104 VVLYHGVEEPARRWMRKMVDVRAVSARSDPGEPANTKLHPIDRPLEAISA MAB_0401|M.abscessus_ATCC_1997 MALYHWVEEPGRRWMRRMIGVTKP-AITDHHASHNGHKARVP-ENLTEPE MSMEG_3490|M.smegmatis_MC2_155 MVLYHVVEEPARRWMRRMVDIRP-------VDPKNSHLHRVDAEHQGHSA TH_1720|M.thermoresistible__bu IPVAWLLHRFTRPPIRPAVPARS--------------ADRTDRR------ MLBr_02670|M.leprae_Br4923 ATMWVIPVGTETGLRDIALPPEVSTVAAVSPSPPRGKLSSTRDPNQPFTV : : Mflv_3267|M.gilvum_PYR-GCK RAG----------------------------------------------- Mvan_2986|M.vanbaalenii_PYR-1 RAG----------------------------------------------- MMAR_0854|M.marinum_M RAV----------------------------------------------- MUL_0606|M.ulcerans_Agy99 RAV----------------------------------------------- Mb0530|M.bovis_AF2122/97 RAV----------------------------------------------- Rv0517|M.tuberculosis_H37Rv RAV----------------------------------------------- MAV_4633|M.avium_104 RAV----------------------------------------------- MAB_0401|M.abscessus_ATCC_1997 REPVVTGVTTR--------------------------------------- MSMEG_3490|M.smegmatis_MC2_155 AVPARAG------------------------------------------- TH_1720|M.thermoresistible__bu -------------------------------------------------- MLBr_02670|M.leprae_Br4923 AVFGDSIGWTWMHYLPPTPGFAFIDHTVIGCSLVRGTPYQYIGQTLEQRP Mflv_3267|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2986|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_0854|M.marinum_M -------------------------------------------------- MUL_0606|M.ulcerans_Agy99 -------------------------------------------------- Mb0530|M.bovis_AF2122/97 -------------------------------------------------- Rv0517|M.tuberculosis_H37Rv -------------------------------------------------- MAV_4633|M.avium_104 -------------------------------------------------- MAB_0401|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_3490|M.smegmatis_MC2_155 -------------------------------------------------- TH_1720|M.thermoresistible__bu -------------------------------------------------- MLBr_02670|M.leprae_Br4923 ECDNWPIRWSTQINKDHPNVALLIIGRWETVNRVNEGQWTHIGDPTFDSY Mflv_3267|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2986|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_0854|M.marinum_M -------------------------------------------------- MUL_0606|M.ulcerans_Agy99 -------------------------------------------------- Mb0530|M.bovis_AF2122/97 -------------------------------------------------- Rv0517|M.tuberculosis_H37Rv -------------------------------------------------- MAV_4633|M.avium_104 -------------------------------------------------- MAB_0401|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_3490|M.smegmatis_MC2_155 -------------------------------------------------- TH_1720|M.thermoresistible__bu -------------------------------------------------- MLBr_02670|M.leprae_Br4923 LNAELQQALNILGSSGVRVVVATVPYSRGGEKPDGQLYPEDQPDRVNQWN Mflv_3267|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2986|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_0854|M.marinum_M -------------------------------------------------- MUL_0606|M.ulcerans_Agy99 -------------------------------------------------- Mb0530|M.bovis_AF2122/97 -------------------------------------------------- Rv0517|M.tuberculosis_H37Rv -------------------------------------------------- MAV_4633|M.avium_104 -------------------------------------------------- MAB_0401|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_3490|M.smegmatis_MC2_155 -------------------------------------------------- TH_1720|M.thermoresistible__bu -------------------------------------------------- MLBr_02670|M.leprae_Br4923 TMLRNTVSQHSNVQILDLNKKLCPDGVYTAKVDGIKVRSDGVHLTPEGVK Mflv_3267|M.gilvum_PYR-GCK ----------- Mvan_2986|M.vanbaalenii_PYR-1 ----------- MMAR_0854|M.marinum_M ----------- MUL_0606|M.ulcerans_Agy99 ----------- Mb0530|M.bovis_AF2122/97 ----------- Rv0517|M.tuberculosis_H37Rv ----------- MAV_4633|M.avium_104 ----------- MAB_0401|M.abscessus_ATCC_1997 ----------- MSMEG_3490|M.smegmatis_MC2_155 ----------- TH_1720|M.thermoresistible__bu ----------- MLBr_02670|M.leprae_Br4923 WLTPWLEESLK