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M. marinum M MMAR_0854 (-)

annotation: membrane acyltransferase
coordinates: 1043117 - 1044436
length: 439

VRWLDPRVSRTSRRTRQRISRWRERGKTIVRSPMLRGEIKALTGLRIVAAVWVVLFHFRPMLADASPDFR
ENLAPVLNCGAQGVDLFFILSGFVLTWNYLDRMGHSWSTRATLHFLWLRLARVWPVYLVTMHLAALLVIM
TLHVGHVPLPEVGQLTAVSYIRQVLMVQLWFQPFFDDSSWDGPAWSISAEWLAYLLFGALVLVIFRMTHA
TRARNLMWLAFAASLPPVILLLASGQFYTPWSWLPRIVTQFVAGALAAAAVRRLRLTDRARRASGYLSVL
LIAAIVGILYLVDAHPISGVVDSGGVVDVLFVPLIVTLAVGVGSLPRLLSTRVMVYGGEISFCLYMVHEL
VHTAWGWAVLQFELTPQDNPWKWNVIGLLVIAVAASVLLYHFIEEPARRWMRRMVDVRAVTARIEPSEPV
NGKRNQADGALEGFSARAV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0854--100% (439)membrane acyltransferase
M. marinum MMMAR_0312-2e-1326.20% (439) transmembrane acyltransferase
M. marinum MMMAR_4188-2e-1224.17% (331) integral membrane acyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0530-0.078.44% (436) membrane acyltransferase
M. gilvum PYR-GCKMflv_3267-1e-15064.78% (406) acyltransferase 3
M. tuberculosis H37RvRv0517-0.078.44% (436) membrane acyltransferase
M. leprae Br4923MLBr_02670-2e-1324.70% (417) hypothetical protein MLBr_02670
M. abscessus ATCC 19977MAB_0401-1e-16374.12% (371) putative acyltransferase
M. avium 104MAV_4633-0.078.64% (412) putative acyltransferase, putative
M. smegmatis MC2 155MSMEG_3490-1e-16269.50% (400) putative membrane acyltransferase
M. thermoresistible (build 8)TH_1720-8e-1625.06% (387) PROBABLE ACYLTRANSFERASE
M. ulcerans Agy99MUL_0606-0.099.09% (439) membrane acyltransferase
M. vanbaalenii PYR-1Mvan_2986-1e-15366.91% (405) acyltransferase 3

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3267|M.gilvum_PYR-GCK          ------------------------------------MSRVRTGEIRALSG
Mvan_2986|M.vanbaalenii_PYR-1       ------------------------------------MSRVRTGEIRALSG
MMAR_0854|M.marinum_M               ------MRWLDPRVSRTSRRTRQRISRWRERGKTIVRSPMLRGEIKALTG
MUL_0606|M.ulcerans_Agy99           MPVGGLVRWLDPRVSRTSRRTRQRISRWRERGKTIVRSPMLQGEIKALTG
Mb0530|M.bovis_AF2122/97            -----MAGGMDQPPGQPRRRTRQQSS----DGKNGVRAAEITGEIRALTG
Rv0517|M.tuberculosis_H37Rv         -----MAGGMDQPPGQPRRRTRQQSS----DGKNGVRAAEITGEIRALTG
MAV_4633|M.avium_104                -----------------------------------MRGGEIRGEIKALTG
MAB_0401|M.abscessus_ATCC_1997      -----------------------------------MRG----GEIKALTG
MSMEG_3490|M.smegmatis_MC2_155      -----------------------------------MRG----AEIKALTG
TH_1720|M.thermoresistible__bu      ----------------------VRPSPETDLDQGGLEQVSTVDRVAALTG
MLBr_02670|M.leprae_Br4923          --------------------------MRRVGLLRIWNQPERRNGIPALDG
                                                                                : ** *

Mflv_3267|M.gilvum_PYR-GCK          LRIVAALWVVLFHFRPMLAESAPGFTSALAPVLNAGAQGVDLFFILSGFV
Mvan_2986|M.vanbaalenii_PYR-1       LRIVAALWVVLFHFRPLLAEAAPGFNSALAPILNAGAQGVDLFFILSGFV
MMAR_0854|M.marinum_M               LRIVAAVWVVLFHFRPMLADASPDFRENLAPVLNCGAQGVDLFFILSGFV
MUL_0606|M.ulcerans_Agy99           LRIVAAAWVVLFHFRPMLADASPDFRENLAPVLNCGAQGVDLFFILSGFV
Mb0530|M.bovis_AF2122/97            LRIVAAVWVVLFHFRPMLGDASPGFRDALAPVLDCGAQGVDLFFILSGFV
Rv0517|M.tuberculosis_H37Rv         LRIVAAVWVVLFHFRPMLGDASPGFRDALAPVLDCGAQGVDLFFILSGFV
MAV_4633|M.avium_104                LRIVAALWVVLFHFRPMLGDASPDLRDALAPVLNCGAQGVDLFFILSGFV
MAB_0401|M.abscessus_ATCC_1997      LRIIAAFWVVLFHFRPLLEQAAPEFRTALNPILNCGAQGVDLFFILSGFV
MSMEG_3490|M.smegmatis_MC2_155      LRIVAAVWVVLFHFRPILYEAAPDFTETFAPVLDCGAQGVDLFFILSGFV
TH_1720|M.thermoresistible__bu      VRAVAALSVMGTHAAYGTGTYNHGYVGLIFARMDIG---VAVFFVLSGFL
MLBr_02670|M.leprae_Br4923          LRAIAVALVLTQHGG--------------IPGLSGGFIGVDLFFVLSGFL
                                    :* :*.  *:  *                 . :. *   * :**:****:

Mflv_3267|M.gilvum_PYR-GCK          LAWNYLDRMGDSWSTRSTLRFLWLRLARVWPVYLVTMHLAA-AFAVFTLY
Mvan_2986|M.vanbaalenii_PYR-1       LTWNYLDRMGESWSTRSTLRFLWLRLARVWPVYLVTMHLAA-AFAIFTLY
MMAR_0854|M.marinum_M               LTWNYLDRMGHSWSTRATLHFLWLRLARVWPVYLVTMHLAA-LLVIMTLH
MUL_0606|M.ulcerans_Agy99           LTWNYLDRMGHSWSTRATLHFLWLRLARVWPVYLVTMHLAA-LLVIMTLH
Mb0530|M.bovis_AF2122/97            LTWNYLDRMGRSWSVRANLHFLWLRLARVWPVYLVTLHLAA-VWVIFTLH
Rv0517|M.tuberculosis_H37Rv         LTWNYLDRMGRSWSVRANLHFLWLRLARVWPVYLVTLHLAA-VWVIFTLH
MAV_4633|M.avium_104                LTYNYLDRMGRSFSTRATLHFLWLRLARVWPVYLVTLHLAA-LWVIFTLH
MAB_0401|M.abscessus_ATCC_1997      LTWNYLDRMGHRWSTRETLHFLWLRLARVWPVYLVTMHLAA-LWVIFTMH
MSMEG_3490|M.smegmatis_MC2_155      LTWNYLDRMGPGWSTRATLHFLWLRLSRVWPVYLVTLHLAA-LWVIFTLN
TH_1720|M.thermoresistible__bu      LFRPWVRAAADGTAAPSVRRYARNRVRRIMPAYVVTVLAAYGIYAVRELE
MLBr_02670|M.leprae_Br4923          ITSLLLDELRHTG-RIDAINFWIRRACRLLPALVLMVLTVGIARELFPYQ
                                    :    :             .:   *  *: *. :: :  .     :    

Mflv_3267|M.gilvum_PYR-GCK          IGGFPLPPPVIESLNALSWLKQVFLVQLWFQPYFDGSSWNGP--AWSISA
Mvan_2986|M.vanbaalenii_PYR-1       VGGHPLPPPVIESLNAMSWLKQVLLTQLWFQPYFDGSSWNGP--AWSISA
MMAR_0854|M.marinum_M               VG--HVPLPEVGQLTAVSYIRQVLMVQLWFQPFFDDSSWDGP--AWSISA
MUL_0606|M.ulcerans_Agy99           VG--HVPLPEVGQLTAVSYIRQVLMVQLWFQPFFDDSSWDGP--AWSISA
Mb0530|M.bovis_AF2122/97            VG--HVPSPEAGQLTAISYVRQILLVQLWFQPYFDGSSWDGP--AWSISA
Rv0517|M.tuberculosis_H37Rv         VG--HVPSPEAGQLTAISYVRQILLVQLWFQPYFDGSSWDGP--AWSISA
MAV_4633|M.avium_104                VG--HVPSPDAASLTAISYVRQILLVQLWFVPFFDDSSWDGP--AWSISA
MAB_0401|M.abscessus_ATCC_1997      VG--HVP-ERIDTFDATNYVRQLFMVQLWFRPYFDLSSWNGP--AWSISA
MSMEG_3490|M.smegmatis_MC2_155      VG--HVPVEDTSGYNAVSYLRQLFLVQLWFEPYFDGTSWDGP--AWSISA
TH_1720|M.thermoresistible__bu      PN---------PGHTWVGLLRNLTLTQIYSDDYLTAYAHQGLTQMWSLAV
MLBr_02670|M.leprae_Br4923          ALT----NLRNDAIATFLWVANWRFVVHKADYFTQGTPPSPLQHAWSLGV
                                                       : :  :.      :    . .     **:..

Mflv_3267|M.gilvum_PYR-GCK          EWLAYLLFGGLVLIIFRIASATRARGLMWLAIAAALAPTLLLLAHGVFYT
Mvan_2986|M.vanbaalenii_PYR-1       EWLAYLLFGGLVLIIFRIASATRARGLIWLAIAAALAPTLLLLAHGVFYT
MMAR_0854|M.marinum_M               EWLAYLLFGALVLVIFRMTHATRARNLMWLAFAASLPPVILLLASGQFYT
MUL_0606|M.ulcerans_Agy99           EWLAYLLFGALVLVIFRMTHATRARNLMWLAFAASLPPVILLLASGQFYT
Mb0530|M.bovis_AF2122/97            EWLAYLLFGLLILVIFRMKHATRARGLMWLAFAASLPPVVLLLASGQFYT
Rv0517|M.tuberculosis_H37Rv         EWLAYLLFGLLILVIFRMKHATRARGLMWLAFAASLPPVVLLLASGQFYT
MAV_4633|M.avium_104                EWLAYVLFAGMVLVLLRMKQATRARSLMVLAFAASLPPVVMLLASGHFYT
MAB_0401|M.abscessus_ATCC_1997      EWLAYLLFGGLVLVIFRMAHATRARSLMVLAVLASLPPVMLLLLTGQFYT
MSMEG_3490|M.smegmatis_MC2_155      EWLAYLLFGALILVVFRIARATRARSLVVLAVAASLPPVVLLMMTGHFYT
TH_1720|M.thermoresistible__bu      EVAFYAALPVLAWLLLVVLARRRWRPVPLLTGLGVLAVVSPLWVVVLHRT
MLBr_02670|M.leprae_Br4923          EEQYYLVWPLLLIAVTLLLAARARRRCRYATLGAVRLAVFVLASLGALAS
                                    *   *     :   :  :      *     :  .    .  *       :

Mflv_3267|M.gilvum_PYR-GCK          PWS------WLPRIIMQFTAG-----ALACAAVRKLVLTEST--------
Mvan_2986|M.vanbaalenii_PYR-1       PWS------WLPRIVMQFTAG-----ALACAAVRKLVLTDRT--------
MMAR_0854|M.marinum_M               PWS------WLPRIVTQFVAG-----ALAAAAVRRLRLTDRA--------
MUL_0606|M.ulcerans_Agy99           PWR------WLPRIVTQFVAG-----ALAAAAVRRLRLTDRA--------
Mb0530|M.bovis_AF2122/97            PWS------WLPRIVTQFAAG-----ALACAAVRRLRPTDRA--------
Rv0517|M.tuberculosis_H37Rv         PWS------WLPRIVTQFAAG-----ALACAAVRRLRPTDRA--------
MAV_4633|M.avium_104                PWS------WLPRIVTQFTAG-----ALACAAVRRLRLTDQG--------
MAB_0401|M.abscessus_ATCC_1997      PWS------WLPRIVMQFTAG-----ALACAAVSRLKLSHRS--------
MSMEG_3490|M.smegmatis_MC2_155      PWS------WLPRIVMQFTAG-----ALACAAVRKLEPGDTA--------
TH_1720|M.thermoresistible__bu      DWLPLGAGFWLPHYLIWFVGGM----VLAVLQAQGVRAYAAA--------
MLBr_02670|M.leprae_Br4923          ATVAIARVCDVTRDRIYFGTDTRAQALLVGAAASALLVRDWPSLNRGWCL
                                              :.:    *  .      *.   .  :              

Mflv_3267|M.gilvum_PYR-GCK          --RRAAGIASLLLGVAIVGGLYALDTWPPGDML--DAGGLVDVLFVPLVI
Mvan_2986|M.vanbaalenii_PYR-1       --QKAAGVASLLMGAAIVGGLYLLDANRPGDML--DAGGLVDVLFVPLVI
MMAR_0854|M.marinum_M               --RRASGYLSVLLIAAIVGILYLVDAHPISGVV--DSGGVVDVLFVPLIV
MUL_0606|M.ulcerans_Agy99           --RRASGYLSVLLIAAIVGILYLVDAHPISGVV--DSGGVVDVLFVPLIV
Mb0530|M.bovis_AF2122/97            --RRIAGYLSVLVGVAIVGILYLLHAHPLAGVE--DSGGVVDVLFVPLVI
Rv0517|M.tuberculosis_H37Rv         --RRIAGYLSVLVGVAIVGILYLLHAHPLAGVE--DSGGVVDVLFVPLVI
MAV_4633|M.avium_104                --RRIAGYISLLLLAAMVGVLYWFGAHPISGVVENDSGGVVDVLFVPLVI
MAB_0401|M.abscessus_ATCC_1997      --RHVAGYAALLIVASIVGALYFLDAHPISGVV--DSSGVVDVLFVPLVM
MSMEG_3490|M.smegmatis_MC2_155      --RRTAGYLSVVLSIAIIVGLFFFDAHPLNTVG--DAGGLVDILFVPLVV
TH_1720|M.thermoresistible__bu      --TVPVAVAAYLIVATPIAGDTGAPVLNLGQDL--AKVMFYAVIATLVVA
MLBr_02670|M.leprae_Br4923          IRTRWGQLIARFLPVLGLAGLAAATHYATGGAGDFRHGLLIGVAIAAVIV
                                             : .:    :                     .  :  . :: 

Mflv_3267|M.gilvum_PYR-GCK          ALSIG---AGTLPAFLSTRVMVYLGHISFGLYMVHEIVHTMWN-------
Mvan_2986|M.vanbaalenii_PYR-1       TLAIG---AGTLPALLSTPVMVYLGHISFGLYMVHEIVHTAWN-------
MMAR_0854|M.marinum_M               TLAVG---VGSLPRLLSTRVMVYGGEISFCLYMVHELVHTAWG-------
MUL_0606|M.ulcerans_Agy99           TLAVG---VGSLPRLLSTRVMVYGGEISFCLYMVHEPVHTAWG-------
Mb0530|M.bovis_AF2122/97            SLAIG---VGSLPALLSTRLMVFGGQISFCLYMVHELVHTAWG-------
Rv0517|M.tuberculosis_H37Rv         SLAIG---VGSLPALLSTRLMVFGGQISFCLYMVHELVHTAWG-------
MAV_4633|M.avium_104                SLAVG---LGSLPRVLSARAMVYGGKISFCLYMVHELVHTSWG-------
MAB_0401|M.abscessus_ATCC_1997      ALAVG---IGPLPTVLSTRIMVYGGQISFGLYMVHELVHVSWT-------
MSMEG_3490|M.smegmatis_MC2_155      ALAIG---TGSLPALLSTRVLVYGGQISFGLYMVHELVHTAWI-------
TH_1720|M.thermoresistible__bu      PPALGN--RGWYTRMLGSRPMVWLGEISYEIFLVHVIVMEIAM-------
MLBr_02670|M.leprae_Br4923          IAPVALEQRGTVARLLALRPLVWLGTISYGIYLWHWPIFLALNGERTGWS
                                      .:.    *  . .*.   :*: * **: ::: *  :            

Mflv_3267|M.gilvum_PYR-GCK          -------------------WAVLQFDIVLTPSWWAKLVVLGLILFAGIAA
Mvan_2986|M.vanbaalenii_PYR-1       -------------------WAVLQFGIQLAPSWWAKFVVLGLILFAGVAA
MMAR_0854|M.marinum_M               -------------------WAVLQFELTP-QDNPWKWNVIGLLVIAVAAS
MUL_0606|M.ulcerans_Agy99           -------------------WAVLQFELTP-QDNPWKWNVIGLLVIAVAAS
Mb0530|M.bovis_AF2122/97            -------------------WAVQQYELAL-QDQPWKWNVVGLLAIALGAA
Rv0517|M.tuberculosis_H37Rv         -------------------WAVQQYELAL-QDQPWKWNVVGLLAIALGAA
MAV_4633|M.avium_104                -------------------WAVEQFELVT-QDNPWKWNVIGLLAIALAGA
MAB_0401|M.abscessus_ATCC_1997      -------------------WATKQFELSL-LDPGGGWIVIGLLVLAVILS
MSMEG_3490|M.smegmatis_MC2_155      -------------------WTVKQFELTMSPDLSGKATLLGLLAISVVAA
TH_1720|M.thermoresistible__bu      -------------------VSVLRWPVYT-------GSVLGLFATTLALT
MLBr_02670|M.leprae_Br4923          GVPLFASRCSATVAVAAVSWWLIEQPIRHWRPVRVPLLPLAAATVASAAA
                                                           .  :            :.    :   :

Mflv_3267|M.gilvum_PYR-GCK          AVLYHVVEEPARRWMRRMIEPERP--------RAAAASEPSTGRLQSVAA
Mvan_2986|M.vanbaalenii_PYR-1       ALLYHVVEEPARRWMRRMVEPNRA--------RPAQPTETAAGRLKPVAA
MMAR_0854|M.marinum_M               VLLYHFIEEPARRWMRRMVDVRAVTARIEPSEPVNGKRNQADGALEGFSA
MUL_0606|M.ulcerans_Agy99           VLLYHFIEEPARRWMRRMVDVRAVTARIEPSEPVNGKRNQADGALEGFSA
Mb0530|M.bovis_AF2122/97            ILLYHFVEEPDRRWMRRMVDVKAASARSEPGEPVGSTRYQIDDALEGVSA
Rv0517|M.tuberculosis_H37Rv         ILLYHFVEEPGRRWMRRMVDVKAASARSEPGEPVGSTRYQIDDALEGVSA
MAV_4633|M.avium_104                VVLYHGVEEPARRWMRKMVDVRAVSARSDPGEPANTKLHPIDRPLEAISA
MAB_0401|M.abscessus_ATCC_1997      MALYHWVEEPGRRWMRRMIGVTKP-AITDHHASHNGHKARVP-ENLTEPE
MSMEG_3490|M.smegmatis_MC2_155      MVLYHVVEEPARRWMRRMVDIRP-------VDPKNSHLHRVDAEHQGHSA
TH_1720|M.thermoresistible__bu      IPVAWLLHRFTRPPIRPAVPARS--------------ADRTDRR------
MLBr_02670|M.leprae_Br4923          ATMWVIPVGTETGLRDIALPPEVSTVAAVSPSPPRGKLSSTRDPNQPFTV
                                      :               :                               

Mflv_3267|M.gilvum_PYR-GCK          RAG-----------------------------------------------
Mvan_2986|M.vanbaalenii_PYR-1       RAG-----------------------------------------------
MMAR_0854|M.marinum_M               RAV-----------------------------------------------
MUL_0606|M.ulcerans_Agy99           RAV-----------------------------------------------
Mb0530|M.bovis_AF2122/97            RAV-----------------------------------------------
Rv0517|M.tuberculosis_H37Rv         RAV-----------------------------------------------
MAV_4633|M.avium_104                RAV-----------------------------------------------
MAB_0401|M.abscessus_ATCC_1997      REPVVTGVTTR---------------------------------------
MSMEG_3490|M.smegmatis_MC2_155      AVPARAG-------------------------------------------
TH_1720|M.thermoresistible__bu      --------------------------------------------------
MLBr_02670|M.leprae_Br4923          AVFGDSIGWTWMHYLPPTPGFAFIDHTVIGCSLVRGTPYQYIGQTLEQRP
                                                                                      

Mflv_3267|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2986|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_0854|M.marinum_M               --------------------------------------------------
MUL_0606|M.ulcerans_Agy99           --------------------------------------------------
Mb0530|M.bovis_AF2122/97            --------------------------------------------------
Rv0517|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_4633|M.avium_104                --------------------------------------------------
MAB_0401|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_3490|M.smegmatis_MC2_155      --------------------------------------------------
TH_1720|M.thermoresistible__bu      --------------------------------------------------
MLBr_02670|M.leprae_Br4923          ECDNWPIRWSTQINKDHPNVALLIIGRWETVNRVNEGQWTHIGDPTFDSY
                                                                                      

Mflv_3267|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2986|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_0854|M.marinum_M               --------------------------------------------------
MUL_0606|M.ulcerans_Agy99           --------------------------------------------------
Mb0530|M.bovis_AF2122/97            --------------------------------------------------
Rv0517|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_4633|M.avium_104                --------------------------------------------------
MAB_0401|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_3490|M.smegmatis_MC2_155      --------------------------------------------------
TH_1720|M.thermoresistible__bu      --------------------------------------------------
MLBr_02670|M.leprae_Br4923          LNAELQQALNILGSSGVRVVVATVPYSRGGEKPDGQLYPEDQPDRVNQWN
                                                                                      

Mflv_3267|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2986|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_0854|M.marinum_M               --------------------------------------------------
MUL_0606|M.ulcerans_Agy99           --------------------------------------------------
Mb0530|M.bovis_AF2122/97            --------------------------------------------------
Rv0517|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_4633|M.avium_104                --------------------------------------------------
MAB_0401|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_3490|M.smegmatis_MC2_155      --------------------------------------------------
TH_1720|M.thermoresistible__bu      --------------------------------------------------
MLBr_02670|M.leprae_Br4923          TMLRNTVSQHSNVQILDLNKKLCPDGVYTAKVDGIKVRSDGVHLTPEGVK
                                                                                      

Mflv_3267|M.gilvum_PYR-GCK          -----------
Mvan_2986|M.vanbaalenii_PYR-1       -----------
MMAR_0854|M.marinum_M               -----------
MUL_0606|M.ulcerans_Agy99           -----------
Mb0530|M.bovis_AF2122/97            -----------
Rv0517|M.tuberculosis_H37Rv         -----------
MAV_4633|M.avium_104                -----------
MAB_0401|M.abscessus_ATCC_1997      -----------
MSMEG_3490|M.smegmatis_MC2_155      -----------
TH_1720|M.thermoresistible__bu      -----------
MLBr_02670|M.leprae_Br4923          WLTPWLEESLK