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MSASLGVRCGAAPAGPPDHTSPRDPALTGLRAVAALLVVSTHAAFATGYLLHGYLGTMYARLEIGVAVFF VLSGFLLFRPWVRAAAAGRRAPSARRYGRQRMRRIVPAYVVTVVAVFEIYTVFTPGPNPGQTWQGLLRYL TFTHIYTDDYLVTLLHPGLSQMWSLAVEASFYVALPALAFLVLQVLCRGRWRPGRALVGIALLAAVTPVW LVVVTATDLLPNSAGMWLPAHLAWFAGGMALAVLEAVGARCAAIVAIPVAVGLYLAVSTSLGGTLAGPDP AWTPIVKALLYAVIATLAVAPVALGSRDSYSRVLASRPMVWLGEISYEIFLVHVAVMALTMHLVLGWPLF TGSMPGLIAATLALTVPVAWLLNRVTRPQIKARSDGSNAASALPRCDEASFSAGLSSAAVLAEPVGRNTG S
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4285 | - | - | 100% (421) | acyltransferase 3 |
| M. vanbaalenii PYR-1 | Mvan_4469 | - | e-115 | 58.43% (356) | acyltransferase 3 |
| M. vanbaalenii PYR-1 | Mvan_0251 | - | 2e-43 | 35.33% (368) | acyltransferase 3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1286 | - | 1e-113 | 57.26% (358) | acyltransferase |
| M. gilvum PYR-GCK | Mflv_2226 | - | 1e-112 | 56.04% (364) | acyltransferase 3 |
| M. tuberculosis H37Rv | Rv1254 | - | 1e-113 | 57.26% (358) | acyltransferase |
| M. leprae Br4923 | MLBr_01101 | - | 1e-109 | 55.06% (356) | putative acyltransferase |
| M. abscessus ATCC 19977 | MAB_1404 | - | 1e-101 | 50.26% (384) | acyltransferase |
| M. marinum M | MMAR_4188 | - | 1e-110 | 55.34% (356) | integral membrane acyltransferase |
| M. avium 104 | MAV_1402 | - | 1e-107 | 55.62% (356) | putative acyltransferase, putative |
| M. smegmatis MC2 155 | MSMEG_6230 | - | 1e-121 | 62.01% (358) | acyltransferase |
| M. thermoresistible (build 8) | TH_1720 | - | 1e-124 | 61.98% (363) | PROBABLE ACYLTRANSFERASE |
| M. ulcerans Agy99 | MUL_4492 | - | 1e-110 | 55.34% (356) | integral membrane acyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01101|M.leprae_Br4923 ----------MTLSEERDAQSGLKQVSHVDRVASLTGIRAVAALLIVGTH
MAV_1402|M.avium_104 ----------MTLSEEQDAQGGLEQTSRVDRVASLTGVRAVAALLVVGTH
MMAR_4188|M.marinum_M ----------MTLPEATDAQGGLEQISHVDRVASLTGIRAVAALLVVATH
MUL_4492|M.ulcerans_Agy99 ----------MTLPEATDAQGGLEQISHVDRVASLTGIRAVAALLVVTTH
Mb1286|M.bovis_AF2122/97 ----------MTLPKERAAQGGLERIAHVDRVASLTGIRAVAALLVVGTH
Rv1254|M.tuberculosis_H37Rv ----------MTLPKERAAQGGLERIAHVDRVASLTGIRAVAALLVVGTH
Mflv_2226|M.gilvum_PYR-GCK MISPNRAGRRSTAADDVDVAGGLESVS-TGRVASLTGIRAVAALLVVLTH
MAB_1404|M.abscessus_ATCC_1997 ----------MTAVSPTESAP---VVRASGRVAALTGVRAVAATLVVATH
MSMEG_6230|M.smegmatis_MC2_155 -----MAAAPGPDPTDGADQGGLEQVSRADRIASLTGVRAVAALTVMGTH
TH_1720|M.thermoresistible__bu ---------VRPSPETDLDQGGLEQVSTVDRVAALTGVRAVAALSVMGTH
Mvan_4285|M.vanbaalenii_PYR-1 --------MSASLGVRCGAAPAGPPDHTSPRDPALTGLRAVAALLVVSTH
. * .:***:***** :: **
MLBr_01101|M.leprae_Br4923 AAYTTGKYTHG-------YWGLVGARLEIGVPIFFALSGFLLFSPWVKSA
MAV_1402|M.avium_104 AAYTTGKYTHG-------YWGLVGSRMEIGVPIFFVLSGYLLFRPWVKSA
MMAR_4188|M.marinum_M AAYTTGKYTHG-------YWGLVSARMEIGVPIFFVLSGFLLFRPWVHSA
MUL_4492|M.ulcerans_Agy99 AAYTTGKYTHG-------YWGLVSARMEIGVPIFFVLSGFLLFRPWVHSA
Mb1286|M.bovis_AF2122/97 AAYTTGKYTHG-------YWGLMSSRMEIGVPIFFVLSGFLLFRPWVKSA
Rv1254|M.tuberculosis_H37Rv AAYTTGKYTHG-------YWGLMSSRMEIGVPIFFVLSGFLLFRPWVKSA
Mflv_2226|M.gilvum_PYR-GCK AAYTTGKYPQG-------YVGLVYSRMEIGVPIFFVLSGFLLFLPWVKAA
MAB_1404|M.abscessus_ATCC_1997 AAYSTGNYVVDGVSPWKAYLHLLQSRLEIGVPIFFVLSGFLLFLPWVRAA
MSMEG_6230|M.smegmatis_MC2_155 AAYGTGLLTHG-------YVGLLGARLEIGVAIFFVLSGLLLFRPWVRAV
TH_1720|M.thermoresistible__bu AAYGTGTYNHG-------YVGLIFARMDIGVAVFFVLSGFLLFRPWVRAA
Mvan_4285|M.vanbaalenii_PYR-1 AAFATGYLLHG-------YLGTMYARLEIGVAVFFVLSGFLLFRPWVRAA
**: ** . * : :*::***.:**.*** *** ***::.
MLBr_01101|M.leprae_Br4923 ATGSPPPSVSRYAWHRVRRIMPAYVITVLFAYALYHFRAAGPNPGHSWMG
MAV_1402|M.avium_104 ATGGPPPSLSRYVWHRVRRIMPPYVITVLFAYVLYHFREAGPNPGHSWLG
MMAR_4188|M.marinum_M VTGAPPPSLRRYTAHRVRRIMPAYVVVVLIAYVIYHYRIAGPNPGHSWLG
MUL_4492|M.ulcerans_Agy99 VTGAPPPSLRRYTAHRVRRIMPAYVVVVLIAYVIYHYRIAGPNPGHSWMG
Mb1286|M.bovis_AF2122/97 ATGGPPPSLSRYAWHRVRRIMPAYTVTVLLAYLVYHFRTAGPNPGHTWVG
Rv1254|M.tuberculosis_H37Rv ATGGPPPSLSRYAWHRVRRIMPAYTVTVLLAYLVYHFRTAGPNPGHTWVG
Mflv_2226|M.gilvum_PYR-GCK AAGDAPPSVGRYAWHRVRRIMPAYAVTVIAAYLVYHFRTAGPNPGHTWEG
MAB_1404|M.abscessus_ATCC_1997 ADNTASPSVKRYAWHRFRRIMPAYWILVAIAYIWYHIRDQYPNPGHTWLG
MSMEG_6230|M.smegmatis_MC2_155 ATGAQAPSVRRYARSRVRRIMPAYVVTVLLVFGIYELRSVEPNPGHTWTG
TH_1720|M.thermoresistible__bu ADGTAAPSVRRYARNRVRRIMPAYVVTVLAAYGIYAVRELEPNPGHTWVG
Mvan_4285|M.vanbaalenii_PYR-1 AAGRRAPSARRYGRQRMRRIVPAYVVTVVAVFEIYTVFTPGPNPGQTWQG
. . .** ** *.***:*.* : * .: * ****::* *
MLBr_01101|M.leprae_Br4923 LVRNLTLTQIYTDGYLGSYLHQGLTQMWSLAVEVAFYVALPLLAYLLLVL
MAV_1402|M.avium_104 LARNLTLTQIYCNGYLGKYLHQGLTQMWSLAVEASFYVILPLLAYLLLVL
MMAR_4188|M.marinum_M LVRNLTLTQIYTDGYLGSYLHQGLTQMWSLAVEASFYVLLPFLAYLLLVV
MUL_4492|M.ulcerans_Agy99 LVRNLTLTQIYTDGYLGSYLHQGLTQMWSLAVEASFYVLLPFLAYLLLVV
Mb1286|M.bovis_AF2122/97 LFRNLTLTQIYTDGYLGAFLHQGLTQMWSLAVEVAFYLALPALAYLLLVL
Rv1254|M.tuberculosis_H37Rv LFRNLTLTQIYTDGYLGAFLHQGLTQMWSLAVEVAFYLALPALAYLLLVL
Mflv_2226|M.gilvum_PYR-GCK LFRNLTLTQIYTDDYLFSFLHQGLTQMWSLAVEVAFYVVLPALAYLLLVV
MAB_1404|M.abscessus_ATCC_1997 LFRNLTLTQIYTSNYGYRYIHQGMTQIWSLAVEAAFYVALPFLAWLLVKK
MSMEG_6230|M.smegmatis_MC2_155 LWRHLTLTQIYRGDYYTSYLHQGLTQMWSLAVEVTFYAALPLLAYVLLVV
TH_1720|M.thermoresistible__bu LLRNLTLTQIYSDDYLTAYAHQGLTQMWSLAVEVAFYAALPVLAWLLLVV
Mvan_4285|M.vanbaalenii_PYR-1 LLRYLTFTHIYTDDYLVTLLHPGLSQMWSLAVEASFYVALPALAFLVLQV
* * **:*:** ..* * *::*:******.:** ** **::::
MLBr_01101|M.leprae_Br4923 LCQRRWQPRLVLVVLAGMLLISPGWLILVHPDHWFPDGARLWLPTYLAWF
MAV_1402|M.avium_104 VCRRQWQPKLVLGALAGLALVSPAWLVLVHTDHWFPDGARLWLPTYLAWF
MMAR_4188|M.marinum_M ISRRRWQPKLVVGALLAMATITPGWLVLIHTVSLFPDGARLWLPSYLAWF
MUL_4492|M.ulcerans_Agy99 ISRRRWQPKLVVGALLAMATITPGWLVLIHTVSLFPDGARLWLPSYLAWF
Mb1286|M.bovis_AF2122/97 VCRRRWQPRLLLATMAGLTMISPAWLILVHNTHWMPDGARLWLPTYLAWF
Rv1254|M.tuberculosis_H37Rv VCRRRWQPRLLLATMAGLTMISPAWLILVHNTHWMPDGARLWLPTYLAWF
Mflv_2226|M.gilvum_PYR-GCK LCRRRWRPALLMAGLTALAAVSPAWLWLVHSTDFLPDGAKLWLPGYLVWF
MAB_1404|M.abscessus_ATCC_1997 LCGGQWRPARLLVGLGGLALVTPLWMSLVYTIGAFPDGAKLWLPAYLSWF
MSMEG_6230|M.smegmatis_MC2_155 LCRRHFRPWRLLGGLAVLGAVSPLWLVASH-AGRLPVSAGAWLPHYLVWF
TH_1720|M.thermoresistible__bu LARRRWRPVPLLTGLGVLAVVSPLWVVVLHRTDWLPLGAGFWLPHYLIWF
Mvan_4285|M.vanbaalenii_PYR-1 LCRGRWRPGRALVGIALLAAVTPVWLVVVTATDLLPNSAGMWLPAHLAWF
:. :::* : : : ::* *: :* .* *** :* **
MLBr_01101|M.leprae_Br4923 LGGMILAVLQVMGVRCYAFGAIPLAIICYFIVSTPIAGAPTTSPASLGEA
MAV_1402|M.avium_104 LAGMMLTVLQEMGARAYGFVAIPLAVVSYFIVSTPIAGAPTTSPATLSEA
MMAR_4188|M.marinum_M LGGMLLTVLQAMKVQCYALAALPLATICYFIVATPIAGAPTTSPSALTEA
MUL_4492|M.ulcerans_Agy99 LGGMLLTVLQAMKVQCYALAALPLATICYFIVATPIAGAPTTSPSALTEA
Mb1286|M.bovis_AF2122/97 VGGMMLAVLAAMGVRCYAFVAIPLAVICYFIVSTPIAGAPTTSPTALAEA
Rv1254|M.tuberculosis_H37Rv VGGMMLAVLAAMGVRCYAFVAIPLAVICYFIVSTPIAGAPTTSPTALAEA
Mflv_2226|M.gilvum_PYR-GCK IGGMMLAALQPTGFRAYALACVPLAVVSYVIVSTPIAGEPTTSPAELREA
MAB_1404|M.abscessus_ATCC_1997 VGGMILSVLAVMGVRCYALVTVPLAVICYLIVSTRIAGDPTTSPWALPQA
MSMEG_6230|M.smegmatis_MC2_155 IGGMMLAVLATMGVRCHAAAVLPVAVAGYLVVSTPIAGTTTAFTLTLGED
TH_1720|M.thermoresistible__bu VGGMVLAVLQAQGVRAYAAATVPVAVAAYLIVATPIAGDTGAPVLNLGQD
Mvan_4285|M.vanbaalenii_PYR-1 AGGMALAVLEAVGARCAAIVAIPVAVGLYLAVSTSLGG-TLAGPDPAWTP
.** *:.* :. . :*:* *. *:* :.* . :
MLBr_01101|M.leprae_Br4923 LIKVGFYAAIATLAVAPLTLG--------DLGWYSWLLSSRPMVWLGEIS
MAV_1402|M.avium_104 LFKACFYAVIAALAVAPLALG--------DHGWYSRLLASRPMVWLGEIS
MMAR_4188|M.marinum_M VVKACFYTVIATLAVAPLALG--------DQGWYSQLLASRPMVWLGEIS
MUL_4492|M.ulcerans_Agy99 VVKACFYTVIATLAVAPLALG--------DQGWYSQLLASRPMVWLGEIS
Mb1286|M.bovis_AF2122/97 LVKTAFYAVIAVLAVAPLALG--------DQGWYAQLLASRPMVFLGEIS
Rv1254|M.tuberculosis_H37Rv LVKTAFYAVIAVLAVAPLALG--------DQGWYAQLLASRPMVFLGEIS
Mflv_2226|M.gilvum_PYR-GCK LVKTAFYAVIATLVVAPLALGGRPGADGRESGLYARMLSSRPMVFLGEIS
MAB_1404|M.abscessus_ATCC_1997 LTKSIFYVVIATLLVAPAALG--------DNGWYVRFLSTRPMVWLGEIS
MSMEG_6230|M.smegmatis_MC2_155 ITKTMFYAVIATLMVAPLALG--------STGFYARVMASRPMVWLGEIS
TH_1720|M.thermoresistible__bu LAKVMFYAVIATLVVAPPALG--------NRGWYTRMLGSRPMVWLGEIS
Mvan_4285|M.vanbaalenii_PYR-1 IVKALLYAVIATLAVAPVALG--------SRDSYSRVLASRPMVWLGEIS
: * :*..**.* *** :** . . * .:.:****:*****
MLBr_01101|M.leprae_Br4923 YEIFLIHLVTMEFAMVYVVQDHVYTGSMLNLIVATLVLTIPLAWLLHR--
MAV_1402|M.avium_104 YEIFLIHLITMEFAMDYIVGARVYTGSMLNLFVATLVLTIPLAWLLHR--
MMAR_4188|M.marinum_M YEIFLVHLVTMEFAMVYVVRYRVYTGSMLNLFIATMVITIPLAWVLHR--
MUL_4492|M.ulcerans_Agy99 YEIFLVHLVTMEFAMVYVVRYWVYTGSMLNLFIATMVITIPLAWVLHR--
Mb1286|M.bovis_AF2122/97 YEIFLIHLVTMEIAMVDVLGYRVYTSSMVNLCLVTLVLTIPLAWLLHR--
Rv1254|M.tuberculosis_H37Rv YEIFLIHLVTMEIAMVDVLGYRVYTSSMVNLCLVTLVLTIPLAWLLHR--
Mflv_2226|M.gilvum_PYR-GCK YEIFLIHLVTMELVMVEIVRYPIYTGSVWALFFGTLLMTIPLASLLHR--
MAB_1404|M.abscessus_ATCC_1997 YELFLIHMILMEIVMVDLLHYHVYTGSVVIVFLVTMLVSVPASWLIHRTV
MSMEG_6230|M.smegmatis_MC2_155 YEIFLLHVVVMDLVMEFVLGWHVYTGWAAGLFAATLAATIPVAWVLHR--
TH_1720|M.thermoresistible__bu YEIFLVHVIVMEIAMVSVLRWPVYTGSVLGLFATTLALTIPVAWLLHR--
Mvan_4285|M.vanbaalenii_PYR-1 YEIFLVHVAVMALTMHLVLGWPLFTGSMPGLIAATLALTVPVAWLLNR--
**:**:*: * :.* :: ::*. : *: ::* : :::*
MLBr_01101|M.leprae_Br4923 ------CTRMRS--------------------------------------
MAV_1402|M.avium_104 ------FTRVRD--------------------------------------
MMAR_4188|M.marinum_M ------FTRVRSE-------------------------------------
MUL_4492|M.ulcerans_Agy99 ------FTRVRSE-------------------------------------
Mb1286|M.bovis_AF2122/97 ------FTRVQGDRPS----------------------------------
Rv1254|M.tuberculosis_H37Rv ------FTRVQGDRPS----------------------------------
Mflv_2226|M.gilvum_PYR-GCK ------FTRVRT--------------------------------------
MAB_1404|M.abscessus_ATCC_1997 EVILARSSRLRKSLAQRMR-------------------------------
MSMEG_6230|M.smegmatis_MC2_155 ------LTRP---------------RR-----------------------
TH_1720|M.thermoresistible__bu ------FTRPPIRPAVPARSADRTDRR-----------------------
Mvan_4285|M.vanbaalenii_PYR-1 ------VTRPQIKARSDGSNAASALPRCDEASFSAGLSSAAVLAEPVGRN
:*
MLBr_01101|M.leprae_Br4923 ---
MAV_1402|M.avium_104 ---
MMAR_4188|M.marinum_M ---
MUL_4492|M.ulcerans_Agy99 ---
Mb1286|M.bovis_AF2122/97 ---
Rv1254|M.tuberculosis_H37Rv ---
Mflv_2226|M.gilvum_PYR-GCK ---
MAB_1404|M.abscessus_ATCC_1997 ---
MSMEG_6230|M.smegmatis_MC2_155 ---
TH_1720|M.thermoresistible__bu ---
Mvan_4285|M.vanbaalenii_PYR-1 TGS