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LPVGGLVRWLDPRVSRTSRRTRQRISRWRERGKTIVRSPMLQGEIKALTGLRIVAAAWVVLFHFRPMLAD ASPDFRENLAPVLNCGAQGVDLFFILSGFVLTWNYLDRMGHSWSTRATLHFLWLRLARVWPVYLVTMHLA ALLVIMTLHVGHVPLPEVGQLTAVSYIRQVLMVQLWFQPFFDDSSWDGPAWSISAEWLAYLLFGALVLVI FRMTHATRARNLMWLAFAASLPPVILLLASGQFYTPWRWLPRIVTQFVAGALAAAAVRRLRLTDRARRAS GYLSVLLIAAIVGILYLVDAHPISGVVDSGGVVDVLFVPLIVTLAVGVGSLPRLLSTRVMVYGGEISFCL YMVHEPVHTAWGWAVLQFELTPQDNPWKWNVIGLLVIAVAASVLLYHFIEEPARRWMRRMVDVRAVTARI EPSEPVNGKRNQADGALEGFSARAV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0606 | - | - | 100% (445) | membrane acyltransferase |
| M. ulcerans Agy99 | MUL_4810 | - | 2e-13 | 27.00% (437) | transmembrane acyltransferase |
| M. ulcerans Agy99 | MUL_4492 | - | 3e-12 | 24.17% (331) | integral membrane acyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0530 | - | 0.0 | 77.75% (436) | membrane acyltransferase |
| M. gilvum PYR-GCK | Mflv_3267 | - | 1e-148 | 64.53% (406) | acyltransferase 3 |
| M. tuberculosis H37Rv | Rv0517 | - | 0.0 | 77.75% (436) | membrane acyltransferase |
| M. leprae Br4923 | MLBr_02670 | - | 5e-14 | 25.42% (417) | hypothetical protein MLBr_02670 |
| M. abscessus ATCC 19977 | MAB_0401 | - | 1e-162 | 73.58% (371) | putative acyltransferase |
| M. marinum M | MMAR_0854 | - | 0.0 | 99.09% (439) | membrane acyltransferase |
| M. avium 104 | MAV_4633 | - | 0.0 | 77.91% (412) | putative acyltransferase, putative |
| M. smegmatis MC2 155 | MSMEG_3490 | - | 1e-160 | 68.75% (400) | putative membrane acyltransferase |
| M. thermoresistible (build 8) | TH_2230 | - | 7e-15 | 26.63% (353) | PROBABLE ACYLTRANSFERASE |
| M. vanbaalenii PYR-1 | Mvan_2986 | - | 1e-152 | 66.67% (405) | acyltransferase 3 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3267|M.gilvum_PYR-GCK ------------------------------------MSRVRTGEIRALSG
Mvan_2986|M.vanbaalenii_PYR-1 ------------------------------------MSRVRTGEIRALSG
MUL_0606|M.ulcerans_Agy99 MPVGGLVRWLDPRVSRTSRRTRQRISRWRERGKTIVRSPMLQGEIKALTG
MMAR_0854|M.marinum_M ------MRWLDPRVSRTSRRTRQRISRWRERGKTIVRSPMLRGEIKALTG
Mb0530|M.bovis_AF2122/97 -----MAGGMDQPPGQPRRRTRQQSS----DGKNGVRAAEITGEIRALTG
Rv0517|M.tuberculosis_H37Rv -----MAGGMDQPPGQPRRRTRQQSS----DGKNGVRAAEITGEIRALTG
MAV_4633|M.avium_104 -----------------------------------MRGGEIRGEIKALTG
MAB_0401|M.abscessus_ATCC_1997 -----------------------------------MRG----GEIKALTG
MSMEG_3490|M.smegmatis_MC2_155 -----------------------------------MRG----AEIKALTG
TH_2230|M.thermoresistible__bu -----------------MTVRRGGELTEPDVVQGGLESISRAERVASLTG
MLBr_02670|M.leprae_Br4923 --------------------------MRRVGLLRIWNQPERRNGIPALDG
: :* *
Mflv_3267|M.gilvum_PYR-GCK LRIVAALWVVLFHFRPMLAESAPGFTSALAPVLNAGAQGVDLFFILSGFV
Mvan_2986|M.vanbaalenii_PYR-1 LRIVAALWVVLFHFRPLLAEAAPGFNSALAPILNAGAQGVDLFFILSGFV
MUL_0606|M.ulcerans_Agy99 LRIVAAAWVVLFHFRPMLADASPDFRENLAPVLNCGAQGVDLFFILSGFV
MMAR_0854|M.marinum_M LRIVAAVWVVLFHFRPMLADASPDFRENLAPVLNCGAQGVDLFFILSGFV
Mb0530|M.bovis_AF2122/97 LRIVAAVWVVLFHFRPMLGDASPGFRDALAPVLDCGAQGVDLFFILSGFV
Rv0517|M.tuberculosis_H37Rv LRIVAAVWVVLFHFRPMLGDASPGFRDALAPVLDCGAQGVDLFFILSGFV
MAV_4633|M.avium_104 LRIVAALWVVLFHFRPMLGDASPDLRDALAPVLNCGAQGVDLFFILSGFV
MAB_0401|M.abscessus_ATCC_1997 LRIIAAFWVVLFHFRPLLEQAAPEFRTALNPILNCGAQGVDLFFILSGFV
MSMEG_3490|M.smegmatis_MC2_155 LRIVAAVWVVLFHFRPILYEAAPDFTETFAPVLDCGAQGVDLFFILSGFV
TH_2230|M.thermoresistible__bu IRAVAALLVVLTHAAYTTGRYPQGY---LGLVYSRMEIGVPIFFVLSGFL
MLBr_02670|M.leprae_Br4923 LRAIAVALVLTQHGG--------------IPGLSGGFIGVDLFFVLSGFL
:* :*. *: * . ** :**:****:
Mflv_3267|M.gilvum_PYR-GCK LAWNYLDRMGDSWSTRSTLRFLWLRLARVWPVYLVTMHLAAAFAVFTLYI
Mvan_2986|M.vanbaalenii_PYR-1 LTWNYLDRMGESWSTRSTLRFLWLRLARVWPVYLVTMHLAAAFAIFTLYV
MUL_0606|M.ulcerans_Agy99 LTWNYLDRMGHSWSTRATLHFLWLRLARVWPVYLVTMHLAALLVIMTLHV
MMAR_0854|M.marinum_M LTWNYLDRMGHSWSTRATLHFLWLRLARVWPVYLVTMHLAALLVIMTLHV
Mb0530|M.bovis_AF2122/97 LTWNYLDRMGRSWSVRANLHFLWLRLARVWPVYLVTLHLAAVWVIFTLHV
Rv0517|M.tuberculosis_H37Rv LTWNYLDRMGRSWSVRANLHFLWLRLARVWPVYLVTLHLAAVWVIFTLHV
MAV_4633|M.avium_104 LTYNYLDRMGRSFSTRATLHFLWLRLARVWPVYLVTLHLAALWVIFTLHV
MAB_0401|M.abscessus_ATCC_1997 LTWNYLDRMGHRWSTRETLHFLWLRLARVWPVYLVTMHLAALWVIFTMHV
MSMEG_3490|M.smegmatis_MC2_155 LTWNYLDRMGPGWSTRATLHFLWLRLSRVWPVYLVTLHLAALWVIFTLNV
TH_2230|M.thermoresistible__bu LFGPWVRAAAERRPAPSVKRYAWRRVRRIMPAYVVTV-LAAYAVYHFRDA
MLBr_02670|M.leprae_Br4923 ITSLLLDELRHTG-RIDAINFWIRRACRLLPALVLMVLTVGIARELFPYQ
: : .: * *: *. :: : ..
Mflv_3267|M.gilvum_PYR-GCK GGFPLPPPVIESLNALSWLKQVFLVQLWFQPYFDGSSWNGP--AWSISAE
Mvan_2986|M.vanbaalenii_PYR-1 GGHPLPPPVIESLNAMSWLKQVLLTQLWFQPYFDGSSWNGP--AWSISAE
MUL_0606|M.ulcerans_Agy99 G--HVPLPEVGQLTAVSYIRQVLMVQLWFQPFFDDSSWDGP--AWSISAE
MMAR_0854|M.marinum_M G--HVPLPEVGQLTAVSYIRQVLMVQLWFQPFFDDSSWDGP--AWSISAE
Mb0530|M.bovis_AF2122/97 G--HVPSPEAGQLTAISYVRQILLVQLWFQPYFDGSSWDGP--AWSISAE
Rv0517|M.tuberculosis_H37Rv G--HVPSPEAGQLTAISYVRQILLVQLWFQPYFDGSSWDGP--AWSISAE
MAV_4633|M.avium_104 G--HVPSPDAASLTAISYVRQILLVQLWFVPFFDDSSWDGP--AWSISAE
MAB_0401|M.abscessus_ATCC_1997 G--HVP-ERIDTFDATNYVRQLFMVQLWFRPYFDLSSWNGP--AWSISAE
MSMEG_3490|M.smegmatis_MC2_155 G--HVPVEDTSGYNAVSYLRQLFLVQLWFEPYFDGTSWDGP--AWSISAE
TH_2230|M.thermoresistible__bu G-------PNPGHTWEGLLRNLTHTQIYTDNYLYSYLHQGLTQMWSLAVE
MLBr_02670|M.leprae_Br4923 ALTNLRNDAIATFLWVANWRFVVHKADYFTQGTPPSPLQHA---WSLGVE
. : : : : **:..*
Mflv_3267|M.gilvum_PYR-GCK WLAYLLFGGLVLIIFRIASATRARG------------LMWLAIAAALAPT
Mvan_2986|M.vanbaalenii_PYR-1 WLAYLLFGGLVLIIFRIASATRARG------------LIWLAIAAALAPT
MUL_0606|M.ulcerans_Agy99 WLAYLLFGALVLVIFRMTHATRARN------------LMWLAFAASLPPV
MMAR_0854|M.marinum_M WLAYLLFGALVLVIFRMTHATRARN------------LMWLAFAASLPPV
Mb0530|M.bovis_AF2122/97 WLAYLLFGLLILVIFRMKHATRARG------------LMWLAFAASLPPV
Rv0517|M.tuberculosis_H37Rv WLAYLLFGLLILVIFRMKHATRARG------------LMWLAFAASLPPV
MAV_4633|M.avium_104 WLAYVLFAGMVLVLLRMKQATRARS------------LMVLAFAASLPPV
MAB_0401|M.abscessus_ATCC_1997 WLAYLLFGGLVLVIFRMAHATRARS------------LMVLAVLASLPPV
MSMEG_3490|M.smegmatis_MC2_155 WLAYLLFGALILVVFRIARATRARS------------LVVLAVAASLPPV
TH_2230|M.thermoresistible__bu VAFYAVLPLLAYLLLVVVCRRRWRPG---------LLLTGLAVLAAISPA
MLBr_02670|M.leprae_Br4923 EQYYLVWPLLLIAVTLLLAARARRRCRYATLGAVRLAVFVLASLGALASA
* : : : : * : ** .::...
Mflv_3267|M.gilvum_PYR-GCK LLLLAHGVFYTP---WSWLPRIIMQFTAGALACAAVRK-LVLTES-----
Mvan_2986|M.vanbaalenii_PYR-1 LLLLAHGVFYTP---WSWLPRIVMQFTAGALACAAVRK-LVLTDR-----
MUL_0606|M.ulcerans_Agy99 ILLLASGQFYTP---WRWLPRIVTQFVAGALAAAAVRR-LRLTDR-----
MMAR_0854|M.marinum_M ILLLASGQFYTP---WSWLPRIVTQFVAGALAAAAVRR-LRLTDR-----
Mb0530|M.bovis_AF2122/97 VLLLASGQFYTP---WSWLPRIVTQFAAGALACAAVRR-LRPTDR-----
Rv0517|M.tuberculosis_H37Rv VLLLASGQFYTP---WSWLPRIVTQFAAGALACAAVRR-LRPTDR-----
MAV_4633|M.avium_104 VMLLASGHFYTP---WSWLPRIVTQFTAGALACAAVRR-LRLTDQ-----
MAB_0401|M.abscessus_ATCC_1997 MLLLLTGQFYTP---WSWLPRIVMQFTAGALACAAVSR-LKLSHR-----
MSMEG_3490|M.smegmatis_MC2_155 VLLMMTGHFYTP---WSWLPRIVMQFTAGALACAAVRK-LEPGDT-----
TH_2230|M.thermoresistible__bu WLYLVHTVDWLPDGARLWLPTYLIWFLGGMMLAALQPMGVRAYAL-----
MLBr_02670|M.leprae_Br4923 TVAIARVCDVTRDRIYFGTDTRAQALLVGAAASALLVRDWPSLNRGWCLI
: : : * .*
Mflv_3267|M.gilvum_PYR-GCK TRRAAGIASLLLGVAIVGGLYALDTWPPGDML--DAGGLVDVLFVPLVIA
Mvan_2986|M.vanbaalenii_PYR-1 TQKAAGVASLLMGAAIVGGLYLLDANRPGDML--DAGGLVDVLFVPLVIT
MUL_0606|M.ulcerans_Agy99 ARRASGYLSVLLIAAIVGILYLVDAHPISGVV--DSGGVVDVLFVPLIVT
MMAR_0854|M.marinum_M ARRASGYLSVLLIAAIVGILYLVDAHPISGVV--DSGGVVDVLFVPLIVT
Mb0530|M.bovis_AF2122/97 ARRIAGYLSVLVGVAIVGILYLLHAHPLAGVE--DSGGVVDVLFVPLVIS
Rv0517|M.tuberculosis_H37Rv ARRIAGYLSVLVGVAIVGILYLLHAHPLAGVE--DSGGVVDVLFVPLVIS
MAV_4633|M.avium_104 GRRIAGYISLLLLAAMVGVLYWFGAHPISGVVENDSGGVVDVLFVPLVIS
MAB_0401|M.abscessus_ATCC_1997 SRHVAGYAALLIVASIVGALYFLDAHPISGVV--DSSGVVDVLFVPLVMA
MSMEG_3490|M.smegmatis_MC2_155 ARRTAGYLSVVLSIAIIVGLFFFDAHPLNTVG--DAGGLVDILFVPLVVA
TH_2230|M.thermoresistible__bu VCIPLALICYFIVATPIGGEPTTSPNELWEAW--AKTGFYTVIATLMVAP
MLBr_02670|M.leprae_Br4923 RTRWGQLIARFLPVLGLAGLAAATHYATGGAGDFRHGLLIGVAIAAVIVI
. .: : . : . ::
Mflv_3267|M.gilvum_PYR-GCK LSIG---AGTLPAFLSTRVMVYLGHISFGLYMVHEIVHTMWN--------
Mvan_2986|M.vanbaalenii_PYR-1 LAIG---AGTLPALLSTPVMVYLGHISFGLYMVHEIVHTAWN--------
MUL_0606|M.ulcerans_Agy99 LAVG---VGSLPRLLSTRVMVYGGEISFCLYMVHEPVHTAWG--------
MMAR_0854|M.marinum_M LAVG---VGSLPRLLSTRVMVYGGEISFCLYMVHELVHTAWG--------
Mb0530|M.bovis_AF2122/97 LAIG---VGSLPALLSTRLMVFGGQISFCLYMVHELVHTAWG--------
Rv0517|M.tuberculosis_H37Rv LAIG---VGSLPALLSTRLMVFGGQISFCLYMVHELVHTAWG--------
MAV_4633|M.avium_104 LAVG---LGSLPRVLSARAMVYGGKISFCLYMVHELVHTSWG--------
MAB_0401|M.abscessus_ATCC_1997 LAVG---IGPLPTVLSTRIMVYGGQISFGLYMVHELVHVSWT--------
MSMEG_3490|M.smegmatis_MC2_155 LAIG---TGSLPALLSTRVLVYGGQISFGLYMVHELVHTAWI--------
TH_2230|M.thermoresistible__bu LALGN--KGWYSRVLGSRPMVFLGEISYEIFLIHLILMEVAM--------
MLBr_02670|M.leprae_Br4923 APVALEQRGTVARLLALRPLVWLGTISYGIYLWHWPIFLALNGERTGWSG
.:. * . .*. :*: * **: ::: * :
Mflv_3267|M.gilvum_PYR-GCK ------------------WAVLQFDIVLTPSWWAKLVVLGLILFAGIAAA
Mvan_2986|M.vanbaalenii_PYR-1 ------------------WAVLQFGIQLAPSWWAKFVVLGLILFAGVAAA
MUL_0606|M.ulcerans_Agy99 ------------------WAVLQFELTP-QDNPWKWNVIGLLVIAVAASV
MMAR_0854|M.marinum_M ------------------WAVLQFELTP-QDNPWKWNVIGLLVIAVAASV
Mb0530|M.bovis_AF2122/97 ------------------WAVQQYELAL-QDQPWKWNVVGLLAIALGAAI
Rv0517|M.tuberculosis_H37Rv ------------------WAVQQYELAL-QDQPWKWNVVGLLAIALGAAI
MAV_4633|M.avium_104 ------------------WAVEQFELVT-QDNPWKWNVIGLLAIALAGAV
MAB_0401|M.abscessus_ATCC_1997 ------------------WATKQFELSL-LDPGGGWIVIGLLVLAVILSM
MSMEG_3490|M.smegmatis_MC2_155 ------------------WTVKQFELTMSPDLSGKATLLGLLAISVVAAM
TH_2230|M.thermoresistible__bu ------------------VEILRSPVYT---GSMFWLFVWTMVLTIPLAW
MLBr_02670|M.leprae_Br4923 VPLFASRCSATVAVAAVSWWLIEQPIRHWRPVRVPLLPLAAATVASAAAA
. : : .: :
Mflv_3267|M.gilvum_PYR-GCK VLYHVVEEPARRWMRRMIEPERP--------RAAAASEPSTGRLQSVAAR
Mvan_2986|M.vanbaalenii_PYR-1 LLYHVVEEPARRWMRRMVEPNRA--------RPAQPTETAAGRLKPVAAR
MUL_0606|M.ulcerans_Agy99 LLYHFIEEPARRWMRRMVDVRAVTARIEPSEPVNGKRNQADGALEGFSAR
MMAR_0854|M.marinum_M LLYHFIEEPARRWMRRMVDVRAVTARIEPSEPVNGKRNQADGALEGFSAR
Mb0530|M.bovis_AF2122/97 LLYHFVEEPDRRWMRRMVDVKAASARSEPGEPVGSTRYQIDDALEGVSAR
Rv0517|M.tuberculosis_H37Rv LLYHFVEEPGRRWMRRMVDVKAASARSEPGEPVGSTRYQIDDALEGVSAR
MAV_4633|M.avium_104 VLYHGVEEPARRWMRKMVDVRAVSARSDPGEPANTKLHPIDRPLEAISAR
MAB_0401|M.abscessus_ATCC_1997 ALYHWVEEPGRRWMRRMIGVTKP-AITDHHASHNGHKARVP-ENLTEPER
MSMEG_3490|M.smegmatis_MC2_155 VLYHVVEEPARRWMRRMVDIRP-------VDPKNSHLHRVDAEHQGHSAA
TH_2230|M.thermoresistible__bu LLHRFTRVRDQ---------------------------------------
MLBr_02670|M.leprae_Br4923 TMWVIPVGTETGLRDIALPPEVSTVAAVSPSPPRGKLSSTRDPNQPFTVA
:
Mflv_3267|M.gilvum_PYR-GCK AG------------------------------------------------
Mvan_2986|M.vanbaalenii_PYR-1 AG------------------------------------------------
MUL_0606|M.ulcerans_Agy99 AV------------------------------------------------
MMAR_0854|M.marinum_M AV------------------------------------------------
Mb0530|M.bovis_AF2122/97 AV------------------------------------------------
Rv0517|M.tuberculosis_H37Rv AV------------------------------------------------
MAV_4633|M.avium_104 AV------------------------------------------------
MAB_0401|M.abscessus_ATCC_1997 EPVVTGVTTR----------------------------------------
MSMEG_3490|M.smegmatis_MC2_155 VPARAG--------------------------------------------
TH_2230|M.thermoresistible__bu --------------------------------------------------
MLBr_02670|M.leprae_Br4923 VFGDSIGWTWMHYLPPTPGFAFIDHTVIGCSLVRGTPYQYIGQTLEQRPE
Mflv_3267|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2986|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0606|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0854|M.marinum_M --------------------------------------------------
Mb0530|M.bovis_AF2122/97 --------------------------------------------------
Rv0517|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4633|M.avium_104 --------------------------------------------------
MAB_0401|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3490|M.smegmatis_MC2_155 --------------------------------------------------
TH_2230|M.thermoresistible__bu --------------------------------------------------
MLBr_02670|M.leprae_Br4923 CDNWPIRWSTQINKDHPNVALLIIGRWETVNRVNEGQWTHIGDPTFDSYL
Mflv_3267|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2986|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0606|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0854|M.marinum_M --------------------------------------------------
Mb0530|M.bovis_AF2122/97 --------------------------------------------------
Rv0517|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4633|M.avium_104 --------------------------------------------------
MAB_0401|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3490|M.smegmatis_MC2_155 --------------------------------------------------
TH_2230|M.thermoresistible__bu --------------------------------------------------
MLBr_02670|M.leprae_Br4923 NAELQQALNILGSSGVRVVVATVPYSRGGEKPDGQLYPEDQPDRVNQWNT
Mflv_3267|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2986|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0606|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0854|M.marinum_M --------------------------------------------------
Mb0530|M.bovis_AF2122/97 --------------------------------------------------
Rv0517|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4633|M.avium_104 --------------------------------------------------
MAB_0401|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3490|M.smegmatis_MC2_155 --------------------------------------------------
TH_2230|M.thermoresistible__bu --------------------------------------------------
MLBr_02670|M.leprae_Br4923 MLRNTVSQHSNVQILDLNKKLCPDGVYTAKVDGIKVRSDGVHLTPEGVKW
Mflv_3267|M.gilvum_PYR-GCK ----------
Mvan_2986|M.vanbaalenii_PYR-1 ----------
MUL_0606|M.ulcerans_Agy99 ----------
MMAR_0854|M.marinum_M ----------
Mb0530|M.bovis_AF2122/97 ----------
Rv0517|M.tuberculosis_H37Rv ----------
MAV_4633|M.avium_104 ----------
MAB_0401|M.abscessus_ATCC_1997 ----------
MSMEG_3490|M.smegmatis_MC2_155 ----------
TH_2230|M.thermoresistible__bu ----------
MLBr_02670|M.leprae_Br4923 LTPWLEESLK