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RGAEIKALTGLRIVAAVWVVLFHFRPILYEAAPDFTETFAPVLDCGAQGVDLFFILSGFVLTWNYLDRMG PGWSTRATLHFLWLRLSRVWPVYLVTLHLAALWVIFTLNVGHVPVEDTSGYNAVSYLRQLFLVQLWFEPY FDGTSWDGPAWSISAEWLAYLLFGALILVVFRIARATRARSLVVLAVAASLPPVVLLMMTGHFYTPWSWL PRIVMQFTAGALACAAVRKLEPGDTARRTAGYLSVVLSIAIIVGLFFFDAHPLNTVGDAGGLVDILFVPL VVALAIGTGSLPALLSTRVLVYGGQISFGLYMVHELVHTAWIWTVKQFELTMSPDLSGKATLLGLLAISV VAAMVLYHVVEEPARRWMRRMVDIRPVDPKNSHLHRVDAEHQGHSAAVPARAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3490 | - | - | 100% (404) | putative membrane acyltransferase |
| M. smegmatis MC2 155 | MSMEG_5041 | - | 3e-16 | 25.27% (376) | acyltransferase |
| M. smegmatis MC2 155 | MSMEG_6230 | - | 3e-13 | 26.27% (335) | acyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0530 | - | 1e-163 | 70.00% (400) | membrane acyltransferase |
| M. gilvum PYR-GCK | Mflv_3267 | - | 1e-151 | 64.04% (406) | acyltransferase 3 |
| M. tuberculosis H37Rv | Rv0517 | - | 1e-163 | 70.00% (400) | membrane acyltransferase |
| M. leprae Br4923 | MLBr_01101 | - | 4e-14 | 23.69% (325) | putative acyltransferase |
| M. abscessus ATCC 19977 | MAB_0401 | - | 1e-161 | 67.25% (400) | putative acyltransferase |
| M. marinum M | MMAR_0854 | - | 1e-162 | 69.50% (400) | membrane acyltransferase |
| M. avium 104 | MAV_4633 | - | 1e-158 | 67.24% (406) | putative acyltransferase, putative |
| M. thermoresistible (build 8) | TH_1720 | - | 4e-17 | 24.80% (379) | PROBABLE ACYLTRANSFERASE |
| M. ulcerans Agy99 | MUL_0606 | - | 1e-160 | 68.75% (400) | membrane acyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2986 | - | 1e-148 | 64.30% (409) | acyltransferase 3 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3267|M.gilvum_PYR-GCK ------------------------------------MSRVRTGEIRALSG
Mvan_2986|M.vanbaalenii_PYR-1 ------------------------------------MSRVRTGEIRALSG
Mb0530|M.bovis_AF2122/97 -----MAGGMDQPPGQPRRRTRQQSS----DGKNGVRAAEITGEIRALTG
Rv0517|M.tuberculosis_H37Rv -----MAGGMDQPPGQPRRRTRQQSS----DGKNGVRAAEITGEIRALTG
MAV_4633|M.avium_104 -----------------------------------MRGGEIRGEIKALTG
MMAR_0854|M.marinum_M ------MRWLDPRVSRTSRRTRQRISRWRERGKTIVRSPMLRGEIKALTG
MUL_0606|M.ulcerans_Agy99 MPVGGLVRWLDPRVSRTSRRTRQRISRWRERGKTIVRSPMLQGEIKALTG
MSMEG_3490|M.smegmatis_MC2_155 -----------------------------------MRG----AEIKALTG
MAB_0401|M.abscessus_ATCC_1997 -----------------------------------MRG----GEIKALTG
MLBr_01101|M.leprae_Br4923 ----------------------MTLSEERDA-QSGLKQVSHVDRVASLTG
TH_1720|M.thermoresistible__bu ----------------------VRPSPETDLDQGGLEQVSTVDRVAALTG
.: :*:*
Mflv_3267|M.gilvum_PYR-GCK LRIVAALWVVLFHFRPMLAESAPGFTSALAPVLNAGAQGVDLFFILSGFV
Mvan_2986|M.vanbaalenii_PYR-1 LRIVAALWVVLFHFRPLLAEAAPGFNSALAPILNAGAQGVDLFFILSGFV
Mb0530|M.bovis_AF2122/97 LRIVAAVWVVLFHFRPMLGDASPGFRDALAPVLDCGAQGVDLFFILSGFV
Rv0517|M.tuberculosis_H37Rv LRIVAAVWVVLFHFRPMLGDASPGFRDALAPVLDCGAQGVDLFFILSGFV
MAV_4633|M.avium_104 LRIVAALWVVLFHFRPMLGDASPDLRDALAPVLNCGAQGVDLFFILSGFV
MMAR_0854|M.marinum_M LRIVAAVWVVLFHFRPMLADASPDFRENLAPVLNCGAQGVDLFFILSGFV
MUL_0606|M.ulcerans_Agy99 LRIVAAAWVVLFHFRPMLADASPDFRENLAPVLNCGAQGVDLFFILSGFV
MSMEG_3490|M.smegmatis_MC2_155 LRIVAAVWVVLFHFRPILYEAAPDFTETFAPVLDCGAQGVDLFFILSGFV
MAB_0401|M.abscessus_ATCC_1997 LRIIAAFWVVLFHFRPLLEQAAPEFRTALNPILNCGAQGVDLFFILSGFV
MLBr_01101|M.leprae_Br4923 IRAVAALLIVGTHAAYTTGKYTHGYWGLVGARLEIG---VPIFFALSGFL
TH_1720|M.thermoresistible__bu VRAVAALSVMGTHAAYGTGTYNHGYVGLIFARMDIG---VAVFFVLSGFL
:* :** :: * . . :: * * :** ****:
Mflv_3267|M.gilvum_PYR-GCK LAWNYLDRMGDSWSTRSTLRFLWLRLARVWPVYLVTMHLAAAFAVFTLYI
Mvan_2986|M.vanbaalenii_PYR-1 LTWNYLDRMGESWSTRSTLRFLWLRLARVWPVYLVTMHLAAAFAIFTLYV
Mb0530|M.bovis_AF2122/97 LTWNYLDRMGRSWSVRANLHFLWLRLARVWPVYLVTLHLAAVWVIFTLHV
Rv0517|M.tuberculosis_H37Rv LTWNYLDRMGRSWSVRANLHFLWLRLARVWPVYLVTLHLAAVWVIFTLHV
MAV_4633|M.avium_104 LTYNYLDRMGRSFSTRATLHFLWLRLARVWPVYLVTLHLAALWVIFTLHV
MMAR_0854|M.marinum_M LTWNYLDRMGHSWSTRATLHFLWLRLARVWPVYLVTMHLAALLVIMTLHV
MUL_0606|M.ulcerans_Agy99 LTWNYLDRMGHSWSTRATLHFLWLRLARVWPVYLVTMHLAALLVIMTLHV
MSMEG_3490|M.smegmatis_MC2_155 LTWNYLDRMGPGWSTRATLHFLWLRLSRVWPVYLVTLHLAALWVIFTLNV
MAB_0401|M.abscessus_ATCC_1997 LTWNYLDRMGHRWSTRETLHFLWLRLARVWPVYLVTMHLAALWVIFTMHV
MLBr_01101|M.leprae_Br4923 LFSPWVKSAATGSPPPSVSRYAWHRVRRIMPAYVITVLFAYALYHFRAAG
TH_1720|M.thermoresistible__bu LFRPWVRAAADGTAAPSVRRYARNRVRRIMPAYVVTVLAAYGIYAVRELE
* :: . . :: *: *: *.*::*: * .
Mflv_3267|M.gilvum_PYR-GCK GGFPLPPPVIESLNALSWLKQVFLVQLWFQPYFDGSSWNGP--AWSISAE
Mvan_2986|M.vanbaalenii_PYR-1 GGHPLPPPVIESLNAMSWLKQVLLTQLWFQPYFDGSSWNGP--AWSISAE
Mb0530|M.bovis_AF2122/97 G--HVPSPEAGQLTAISYVRQILLVQLWFQPYFDGSSWDGP--AWSISAE
Rv0517|M.tuberculosis_H37Rv G--HVPSPEAGQLTAISYVRQILLVQLWFQPYFDGSSWDGP--AWSISAE
MAV_4633|M.avium_104 G--HVPSPDAASLTAISYVRQILLVQLWFVPFFDDSSWDGP--AWSISAE
MMAR_0854|M.marinum_M G--HVPLPEVGQLTAVSYIRQVLMVQLWFQPFFDDSSWDGP--AWSISAE
MUL_0606|M.ulcerans_Agy99 G--HVPLPEVGQLTAVSYIRQVLMVQLWFQPFFDDSSWDGP--AWSISAE
MSMEG_3490|M.smegmatis_MC2_155 G--HVPVEDTSGYNAVSYLRQLFLVQLWFEPYFDGTSWDGP--AWSISAE
MAB_0401|M.abscessus_ATCC_1997 G--HVP-ERIDTFDATNYVRQLFMVQLWFRPYFDLSSWNGP--AWSISAE
MLBr_01101|M.leprae_Br4923 P--------NPGHSWMGLVRNLTLTQIYTDGYLGSYLHQGLTQMWSLAVE
TH_1720|M.thermoresistible__bu P--------NPGHTWVGLLRNLTLTQIYSDDYLTAYAHQGLTQMWSLAVE
. :::: :.*:: :: :* **::.*
Mflv_3267|M.gilvum_PYR-GCK WLAYLLFGGLVLIIFRIASATRARG---LMWLAIAAALAPTLLLLAHGVF
Mvan_2986|M.vanbaalenii_PYR-1 WLAYLLFGGLVLIIFRIASATRARG---LIWLAIAAALAPTLLLLAHGVF
Mb0530|M.bovis_AF2122/97 WLAYLLFGLLILVIFRMKHATRARG---LMWLAFAASLPPVVLLLASGQF
Rv0517|M.tuberculosis_H37Rv WLAYLLFGLLILVIFRMKHATRARG---LMWLAFAASLPPVVLLLASGQF
MAV_4633|M.avium_104 WLAYVLFAGMVLVLLRMKQATRARS---LMVLAFAASLPPVVMLLASGHF
MMAR_0854|M.marinum_M WLAYLLFGALVLVIFRMTHATRARN---LMWLAFAASLPPVILLLASGQF
MUL_0606|M.ulcerans_Agy99 WLAYLLFGALVLVIFRMTHATRARN---LMWLAFAASLPPVILLLASGQF
MSMEG_3490|M.smegmatis_MC2_155 WLAYLLFGALILVVFRIARATRARS---LVVLAVAASLPPVVLLMMTGHF
MAB_0401|M.abscessus_ATCC_1997 WLAYLLFGGLVLVIFRMAHATRARS---LMVLAVLASLPPVMLLLLTGQF
MLBr_01101|M.leprae_Br4923 VAFYVALPLLAYLLLVLLCQRRWQPRLVLVVLAGMLLISPGWLILVHPDH
TH_1720|M.thermoresistible__bu VAFYAALPVLAWLLLVVLARRRWRPVPLLTGLGVLAVVSPLWVVVLHRTD
* : : ::: : * : * *. :.* :::
Mflv_3267|M.gilvum_PYR-GCK YTPWS---WLPRIIMQFTAG-ALACAAVRKLVLTESTRRAAGIASLLLGV
Mvan_2986|M.vanbaalenii_PYR-1 YTPWS---WLPRIVMQFTAG-ALACAAVRKLVLTDRTQKAAGVASLLMGA
Mb0530|M.bovis_AF2122/97 YTPWS---WLPRIVTQFAAG-ALACAAVRRLRPTDRARRIAGYLSVLVGV
Rv0517|M.tuberculosis_H37Rv YTPWS---WLPRIVTQFAAG-ALACAAVRRLRPTDRARRIAGYLSVLVGV
MAV_4633|M.avium_104 YTPWS---WLPRIVTQFTAG-ALACAAVRRLRLTDQGRRIAGYISLLLLA
MMAR_0854|M.marinum_M YTPWS---WLPRIVTQFVAG-ALAAAAVRRLRLTDRARRASGYLSVLLIA
MUL_0606|M.ulcerans_Agy99 YTPWR---WLPRIVTQFVAG-ALAAAAVRRLRLTDRARRASGYLSVLLIA
MSMEG_3490|M.smegmatis_MC2_155 YTPWS---WLPRIVMQFTAG-ALACAAVRKLEPGDTARRTAGYLSVVLSI
MAB_0401|M.abscessus_ATCC_1997 YTPWS---WLPRIVMQFTAG-ALACAAVSRLKLSHRSRHVAGYAALLIVA
MLBr_01101|M.leprae_Br4923 WFPDGARLWLPTYLAWFLGGMILAVLQVMGVRCYAFGAIPLAIICYFIVS
TH_1720|M.thermoresistible__bu WLPLGAGFWLPHYLIWFVGGMVLAVLQAQGVRAYAAATVPVAVAAYLIVA
: * *** : * .* ** . : . . .:
Mflv_3267|M.gilvum_PYR-GCK AIVGGLYALDTWPPGDML--DAGGLVDVLFVPLVIALSIG-AGTLPAFLS
Mvan_2986|M.vanbaalenii_PYR-1 AIVGGLYLLDANRPGDML--DAGGLVDVLFVPLVITLAIG-AGTLPALLS
Mb0530|M.bovis_AF2122/97 AIVGILYLLHAHPLAGVE--DSGGVVDVLFVPLVISLAIG-VGSLPALLS
Rv0517|M.tuberculosis_H37Rv AIVGILYLLHAHPLAGVE--DSGGVVDVLFVPLVISLAIG-VGSLPALLS
MAV_4633|M.avium_104 AMVGVLYWFGAHPISGVVENDSGGVVDVLFVPLVISLAVG-LGSLPRVLS
MMAR_0854|M.marinum_M AIVGILYLVDAHPISGVV--DSGGVVDVLFVPLIVTLAVG-VGSLPRLLS
MUL_0606|M.ulcerans_Agy99 AIVGILYLVDAHPISGVV--DSGGVVDVLFVPLIVTLAVG-VGSLPRLLS
MSMEG_3490|M.smegmatis_MC2_155 AIIVGLFFFDAHPLNTVG--DAGGLVDILFVPLVVALAIG-TGSLPALLS
MAB_0401|M.abscessus_ATCC_1997 SIVGALYFLDAHPISGVV--DSSGVVDVLFVPLVMALAVG-IGPLPTVLS
MLBr_01101|M.leprae_Br4923 TPIAGAPTTSPASLGEAL--IKVGFYAAIATLAVAPLTLGDLGWYSWLLS
TH_1720|M.thermoresistible__bu TPIAGDTGAPVLNLGQDL--AKVMFYAVIATLVVAPPALGNRGWYTRMLG
: : . : . : . ::* * . .*.
Mflv_3267|M.gilvum_PYR-GCK TRVMVYLGHISFGLYMVHEIVHTMWNWAVLQFDIVLTPSWWAKLVVLGLI
Mvan_2986|M.vanbaalenii_PYR-1 TPVMVYLGHISFGLYMVHEIVHTAWNWAVLQFGIQLAPSWWAKFVVLGLI
Mb0530|M.bovis_AF2122/97 TRLMVFGGQISFCLYMVHELVHTAWGWAVQQYELAL-QDQPWKWNVVGLL
Rv0517|M.tuberculosis_H37Rv TRLMVFGGQISFCLYMVHELVHTAWGWAVQQYELAL-QDQPWKWNVVGLL
MAV_4633|M.avium_104 ARAMVYGGKISFCLYMVHELVHTSWGWAVEQFELVT-QDNPWKWNVIGLL
MMAR_0854|M.marinum_M TRVMVYGGEISFCLYMVHELVHTAWGWAVLQFELTP-QDNPWKWNVIGLL
MUL_0606|M.ulcerans_Agy99 TRVMVYGGEISFCLYMVHEPVHTAWGWAVLQFELTP-QDNPWKWNVIGLL
MSMEG_3490|M.smegmatis_MC2_155 TRVLVYGGQISFGLYMVHELVHTAWIWTVKQFELTMSPDLSGKATLLGLL
MAB_0401|M.abscessus_ATCC_1997 TRIMVYGGQISFGLYMVHELVHVSWTWATKQFELSL-LDPGGGWIVIGLL
MLBr_01101|M.leprae_Br4923 SRPMVWLGEISYEIFLIHLVTMEFAMVYVVQDHVYT-------GSMLNLI
TH_1720|M.thermoresistible__bu SRPMVWLGEISYEIFLVHVIVMEIAMVSVLRWPVYT-------GSVLGLF
: :*: *.**: ::::* . . : : ::.*:
Mflv_3267|M.gilvum_PYR-GCK LFAGIAAAVLYHVVEEPARRWMRRMIEPERP--------RAAAASEPSTG
Mvan_2986|M.vanbaalenii_PYR-1 LFAGVAAALLYHVVEEPARRWMRRMVEPNRA--------RPAQPTETAAG
Mb0530|M.bovis_AF2122/97 AIALGAAILLYHFVEEPDRRWMRRMVDVKAASARSEPGEPVGSTRYQIDD
Rv0517|M.tuberculosis_H37Rv AIALGAAILLYHFVEEPGRRWMRRMVDVKAASARSEPGEPVGSTRYQIDD
MAV_4633|M.avium_104 AIALAGAVVLYHGVEEPARRWMRKMVDVRAVSARSDPGEPANTKLHPIDR
MMAR_0854|M.marinum_M VIAVAASVLLYHFIEEPARRWMRRMVDVRAVTARIEPSEPVNGKRNQADG
MUL_0606|M.ulcerans_Agy99 VIAVAASVLLYHFIEEPARRWMRRMVDVRAVTARIEPSEPVNGKRNQADG
MSMEG_3490|M.smegmatis_MC2_155 AISVVAAMVLYHVVEEPARRWMRRMVDIRP-------VDPKNSHLHRVDA
MAB_0401|M.abscessus_ATCC_1997 VLAVILSMALYHWVEEPGRRWMRRMIGVTKP-AITDHHASHNGHKARVP-
MLBr_01101|M.leprae_Br4923 VATLVLTIPLAWLLHRCTR--------MRS--------------------
TH_1720|M.thermoresistible__bu ATTLALTIPVAWLLHRFTRPPIRPAVPARSADRTDRR-------------
: : : :.. *
Mflv_3267|M.gilvum_PYR-GCK RLQSVAARAG--------
Mvan_2986|M.vanbaalenii_PYR-1 RLKPVAARAG--------
Mb0530|M.bovis_AF2122/97 ALEGVSARAV--------
Rv0517|M.tuberculosis_H37Rv ALEGVSARAV--------
MAV_4633|M.avium_104 PLEAISARAV--------
MMAR_0854|M.marinum_M ALEGFSARAV--------
MUL_0606|M.ulcerans_Agy99 ALEGFSARAV--------
MSMEG_3490|M.smegmatis_MC2_155 EHQGHSAAVPARAG----
MAB_0401|M.abscessus_ATCC_1997 ENLTEPEREPVVTGVTTR
MLBr_01101|M.leprae_Br4923 ------------------
TH_1720|M.thermoresistible__bu ------------------