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STLYARDEAVIAGIEKLRFFPLEVQSGQGCTLVTPDGRELLDLSATWTASGLGHGHPAVAEAVSRAVRDA PGSGGLSAVHPDSVGLAEDLLALVPGEGERRVYLGHAGSDANDVALRACRHATGRRTVVAFEHSYHGGVG VAMGVSGVHVDAGAPADPDAVFLPYPNPFRPGPDGVEADVAACLDLAEHHLGGGRVACLIVEPILSDGGL VVPPDGFLARLHEVCRRHDVPMICDEVKMGLGRPGTLHAFEHDGVVPDIVTFGKVIGGGLPLSAAVGPAA ILDHPPAAALLTTAGNPVCTAAGRAVLKTIVSEGLVDNAAKVGVVLADSLRTLADSPGGDRIGDVRGRGL AIGLELVDPASGDRDPRLAAAVVYRAWELGAVVYYVGGNVLEITPPLVLTESQAAQAAEIIGAAIGDAAA GKIDAEEVAKYAGW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2918 | - | - | 100% (435) | aminotransferase class-III |
| M. vanbaalenii PYR-1 | Mvan_2581 | - | 7e-60 | 33.64% (428) | 4-aminobutyrate aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_1858 | - | 8e-56 | 34.34% (399) | 4-aminobutyrate aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2620 | gabT | 1e-57 | 32.63% (429) | 4-aminobutyrate aminotransferase |
| M. gilvum PYR-GCK | Mflv_3818 | - | 7e-59 | 34.67% (398) | 4-aminobutyrate aminotransferase |
| M. tuberculosis H37Rv | Rv2589 | gabT | 1e-57 | 32.63% (429) | 4-aminobutyrate aminotransferase |
| M. leprae Br4923 | MLBr_00485 | gabT | 5e-64 | 34.15% (410) | 4-aminobutyrate aminotransferase |
| M. abscessus ATCC 19977 | MAB_4207 | - | 2e-54 | 35.07% (402) | 4-aminobutyrate aminotransferase |
| M. marinum M | MMAR_2465 | argD | 5e-57 | 36.36% (385) | acetylornithine aminotransferase ArgD |
| M. avium 104 | MAV_3470 | gabT | 2e-59 | 33.66% (413) | 4-aminobutyrate aminotransferase |
| M. smegmatis MC2 155 | MSMEG_0581 | gabT | 5e-60 | 34.93% (418) | 4-aminobutyrate transaminase |
| M. thermoresistible (build 8) | TH_3529 | - | 9e-52 | 36.34% (388) | PUTATIVE aminotransferase |
| M. ulcerans Agy99 | MUL_1647 | argD | 5e-57 | 35.32% (402) | acetylornithine aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2620|M.bovis_AF2122/97 -------MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVA
Rv2589|M.tuberculosis_H37Rv -------MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVA
MAV_3470|M.avium_104 -------MARLEQTRRLVTEIPGPASLELSKRRAAAVSHAVNVSVPVFVA
MLBr_00485|M.leprae_Br4923 -------MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVT
Mflv_3818|M.gilvum_PYR-GCK -------MSALEQSRHLATAIPGPRSVELASRKNTAVSRGVGTTMPVYAA
MSMEG_0581|M.smegmatis_MC2_155 MTIAEIAGRTLTQERRLVTAIPGPISQELQARKQSAVAAGVGVTLPVYVV
MAB_4207|M.abscessus_ATCC_1997 ---MTDITYRLAQKRTIVTPLPGPRSGALAERRRAAVSAGVGSTAPVYAV
MMAR_2465|M.marinum_M --------------------MTHTEDTR---ARWEAVMMNNYGTPPVALA
MUL_1647|M.ulcerans_Agy99 --------------------MTHTEDTR---ARWEAVMMNNYGTPPVALA
TH_3529|M.thermoresistible__bu --------------------VSGSKGRHTLLDRWQGVMMNNYGTPPLALV
Mvan_2918|M.vanbaalenii_PYR-1 ------------------------MSTLYARDEAVIAGIEKLRFFPLEVQ
. . *:
Mb2620|M.bovis_AF2122/97 RAGGGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCF
Rv2589|M.tuberculosis_H37Rv RAGGGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCF
MAV_3470|M.avium_104 RAGGGIVEDVDGNRLIDLGSGIAVTTIGNSAPRVVDAVRAQVAEFTHTCF
MLBr_00485|M.leprae_Br4923 RAAGGVIEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTHTCF
Mflv_3818|M.gilvum_PYR-GCK RAFGGIVEDVDGNRLIDLGSGIAVTTVGNASPRVVAAVAEQAAEFTHTCF
MSMEG_0581|M.smegmatis_MC2_155 AAGGGVLADADGNQLIDFGSGIAVTTVGNSAPAVVDAVTQQVAAFTHTCF
MAB_4207|M.abscessus_ATCC_1997 DADGGVIVDADGNSFIDLGAGIAVTTVGASHPAVAAAIADQATHFTHTCF
MMAR_2465|M.marinum_M SGEGAVVTDVDGKNYVDLLGGIAVNILGHRHPAVIEAVTQQMSTLGHTSN
MUL_1647|M.ulcerans_Agy99 SGEGAVVTDVDGKNYVDLLGGIAVNILGHRHPAVIEAVTQQMSTLGHTSN
TH_3529|M.thermoresistible__bu SGDGAVVTDADGKSYLDLLGGIAVNILGHRHPAVIEAVTRQLNTLGHTSN
Mvan_2918|M.vanbaalenii_PYR-1 SGQGCTLVTPDGRELLDLSATWTASGLGHGHPAVAEAVSRAVRDAPGSGG
. * : **. :*: . :.. :* * * *: :
Mb2620|M.bovis_AF2122/97 MVTPYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYTGK
Rv2589|M.tuberculosis_H37Rv MVTPYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYTGK
MAV_3470|M.avium_104 MVTPYESYVAVAETLNRITPGAGEKRSVLFNSGAEAVENAVKVARAYTRK
MLBr_00485|M.leprae_Br4923 IITPYEEYVAVTEQLNRITPGSGEKRSVLFNSGAEAVENSIKVARSYTRK
Mflv_3818|M.gilvum_PYR-GCK MVTPYEGYVAVAEALNRLTPGDGDKRSALFNSGSEAVENAVKIARTFTRK
MSMEG_0581|M.smegmatis_MC2_155 MVTPYEGYVKVAEHLNRLTPGDHEKRTALFNSGAEAVENAVKIARAYTRR
MAB_4207|M.abscessus_ATCC_1997 MVTPYEGYVQVAELLNALTPGDHDKRTALFNSGAEAVENAIKVARLATGR
MMAR_2465|M.marinum_M LYAT-EPTIALAEELVTLLGAEAPARVFFCNSGTEANEAAFKLSR-LTGR
MUL_1647|M.ulcerans_Agy99 LYAT-EPTNALAEELVTLLGAEAPARVFFCNSGTEANEAAFKLSR-LTGR
TH_3529|M.thermoresistible__bu LYAT-EPGVALAEALVGHLG--APARVFFCNSGAEANEVAFKISR-LTGR
Mvan_2918|M.vanbaalenii_PYR-1 LSAVHPDSVGLAEDLLALVPGEGERRVYLGHAGSDANDVALRACRHATGR
: : ::* * * : ::*::* : :.: .* * :
Mb2620|M.bovis_AF2122/97 PAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDG
Rv2589|M.tuberculosis_H37Rv PAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDG
MAV_3470|M.avium_104 PAVVAFDHAYHGRTNLAMALTAKSMPYKGGFGPFAPEIYRAPLSYPYRDG
MLBr_00485|M.leprae_Br4923 PAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDG
Mflv_3818|M.gilvum_PYR-GCK QAVVSFDHAYHGRTNLTMALTAKSMPYKHGFGPFAPEIYRAPMSYPFRDA
MSMEG_0581|M.smegmatis_MC2_155 QAVVVFDHAYHGRTNLTMAMTAKNQPYKHGFGPFANEVYRVPTSYPFRDG
MAB_4207|M.abscessus_ATCC_1997 PAVVAFDNAYHGRTNLTMALTAKSMPYKSQFGPFAPEVYRMPASYPLRD-
MMAR_2465|M.marinum_M TKLVAAQEGFHGRTMGSLALTGQP-AKQAPFEPLPGYVTHVPYG------
MUL_1647|M.ulcerans_Agy99 TKLVAAQEGFHGRTMGSLALTGQP-AKQAPFEPLPGYVTHVPYG------
TH_3529|M.thermoresistible__bu TKVVAAEGGFHGRTMGALALTGQP-SKREPFEPLPGDVIHVPYG------
Mvan_2918|M.vanbaalenii_PYR-1 RTVVAFEHSYHGGVGVAMGVSGVHVDAGA---PADPDAVFLPYPNPFRPG
:* : .:** . ::.::. * *
Mb2620|M.bovis_AF2122/97 LLD-KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAE
Rv2589|M.tuberculosis_H37Rv LLD-KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAE
MAV_3470|M.avium_104 LLD-KELATDGEKAAARAINIIDGQIGADSLAAVIIEPIQGEGGFIVPAE
MLBr_00485|M.leprae_Br4923 LLN-KDLATDGKLAGARAINVIEKQVGADDLAAVIIEPIQGEGGFIVPAE
Mflv_3818|M.gilvum_PYR-GCK EFGGKELATDGELAARRAITVIDKQVGAGNLAAVIIEPIQGEGGFIVPAE
MSMEG_0581|M.smegmatis_MC2_155 ETD-------GAAAAAHALDLINKQVGADNVAAVVIEPVHGEGGFVVPAP
MAB_4207|M.abscessus_ATCC_1997 -----EPGLTGEEAARRAISRIETQIGAQSLAAIIIEPIQGEGGFIVPAP
MMAR_2465|M.marinum_M -----------------DIDALAAAV-DDETAAVFLEPIMGESGVVVPPE
MUL_1647|M.ulcerans_Agy99 -----------------DIDALAAAV-DDETAAVFLEPIMGESGVVVPPE
TH_3529|M.thermoresistible__bu -----------------DAGALERAV-DDTTAAVFLEPIMGEGGVVVPPA
Mvan_2918|M.vanbaalenii_PYR-1 PDG-------VEADVAACLDLAEHHLGGGRVACLIVEPILSDGGLVVPPD
: *.:.:**: .:.*.:**.
Mb2620|M.bovis_AF2122/97 GFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICT
Rv2589|M.tuberculosis_H37Rv GFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICT
MAV_3470|M.avium_104 GFLPTLLDWCRRNDVLFIADEVQTGFARSGAMFACEHEGPNGLEPDLICT
MLBr_00485|M.leprae_Br4923 GFLATLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDG---IVPDLICT
Mflv_3818|M.gilvum_PYR-GCK GFLPTLLDWCRANDVVFIADEVQTGFARTGAMFACEHEGPDGLVPDLIVT
MSMEG_0581|M.smegmatis_MC2_155 GFLGALQKWCTDNGAVFVADEVQTGFARTGALFACEHEN---VVPDLIVT
MAB_4207|M.abscessus_ATCC_1997 GFLATLTAWASENGVVFIADEVQTGFARTGAWFASEHEG---IVPDIVTM
MMAR_2465|M.marinum_M GYLLAAREITARHGALLVLDEVQTGIGRTGAFYAHQHDG---ITPDVVTL
MUL_1647|M.ulcerans_Agy99 GYLLAAREITARHGALLVLDEVQTGIGRTGAFYAHQHDG---ITPDVVTL
TH_3529|M.thermoresistible__bu GYLAAAREVTARHGALLVLDEVQTGIGRTGTFFAHQHDG---ITPDVVTL
Mvan_2918|M.vanbaalenii_PYR-1 GFLARLHEVCRRHDVPMICDEVKMGLGRPGTLHAFEHDG---VVPDIVTF
*:* : . :: ***: *:.*.*: .* :*:. : **::
Mb2620|M.bovis_AF2122/97 AKGIADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIE
Rv2589|M.tuberculosis_H37Rv AKGIADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIE
MAV_3470|M.avium_104 AKAIADGLPLSAVTGRAQIMDAPHVGGLGGTFGGNPLACAAALATIETIE
MLBr_00485|M.leprae_Br4923 AKGIADGLPLAAVTGRAEIMNAPHVSGLGGTFGGNPVACAAALATITTIE
Mflv_3818|M.gilvum_PYR-GCK AKGIAGGMPLSAVTGRADIMDAPHVSGLGGTYGGNPVACAAALATIETIE
MSMEG_0581|M.smegmatis_MC2_155 AKGIAGGLPLSAVTGRAEIMDGPQSGGLGGTYGGNPLACAAALAVIDTIE
MAB_4207|M.abscessus_ATCC_1997 AKGIAGGMPLSAVTGRAELMDAVYAGGLGGTYGGNPVTCAAAVAALGVMR
MMAR_2465|M.marinum_M AKGLGGGLPIGACLAIGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVVA
MUL_1647|M.ulcerans_Agy99 AKGLGGGLPIGACLAIGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVVA
TH_3529|M.thermoresistible__bu AKGLGGGLPIGACLAVGPAGDLLTPGMHGSTFGGNPVCTAAAVAVLGALA
Mvan_2918|M.vanbaalenii_PYR-1 GKVIGGGLPLSAAVGPAAILDHPPAAALLTTAG-NPVCTAAGRAVLKTIV
.* :..*:*:.* . . : . * * **: **. *.: .:
Mb2620|M.bovis_AF2122/97 SDGLIERARQIERLVTDRLTTLQAVD--DRIGDVRGRGAMIAVELVKSGT
Rv2589|M.tuberculosis_H37Rv SDGLIERARQIERLVTDRLTTLQAVD--DRIGDVRGRGAMIAVELVKSGT
MAV_3470|M.avium_104 SDGLIERARQLERLITEPLLRLQARD--DRIGDVRGRGAMIAIELVKSGT
MLBr_00485|M.leprae_Br4923 NDGLIQRAQQIERLITDRLLRLQDAD--DRIGDVRGRGAMIAVELVKSGT
Mflv_3818|M.gilvum_PYR-GCK SDNLVARAAQIEALMKDRLGRMQAED--DRIGDVRGRGAMIAVELVKSGT
MSMEG_0581|M.smegmatis_MC2_155 RENLVARARAIGETMLSRLGALAAAD--PRIGEVRGRGAMIAVELVKPGT
MAB_4207|M.abscessus_ATCC_1997 ELDLPARARAIEASVTSRLSALAEEV--DIIGEVRGRGAMLAIEIVKPGT
MMAR_2465|M.marinum_M SEGLVRRAETLGKTFKQGVESLSHP----LIDHVRGRGLLLGIVLAGP--
MUL_1647|M.ulcerans_Agy99 SEGLVCRAETLGKTFKQGVESLSHP----LIDHVRGRGLLLGIVLAGP--
TH_3529|M.thermoresistible__bu EGDLINRADVLGKKLSHGIEELRHP----LVDHVRGRGLLCGVVLNAP--
Mvan_2918|M.vanbaalenii_PYR-1 SEGLVDNAAKVGVVLADSLRTLADSPGGDRIGDVRGRGLAIGLELVDPAS
.* .* : . : : :..***** .: : .
Mb2620|M.bovis_AF2122/97 TEPDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLD
Rv2589|M.tuberculosis_H37Rv TEPDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLD
MAV_3470|M.avium_104 AEPDKDLTQRLSVAAHAAGVIVLTCGMFGNIIRLLPPLTISDELLAEGID
MLBr_00485|M.leprae_Br4923 AEPDPELTEKVATAAHATGVIILTCGMFGNIIRLLPPLTISDELLAEGLD
Mflv_3818|M.gilvum_PYR-GCK LEPDPELTRKLLTAAHAAGVIVLSCGTFGNVLRFLPPLAISDDLLLEGLD
MSMEG_0581|M.smegmatis_MC2_155 TEPDADLTKRVAAAAHAQGLVVLTCGTYGNVLRFLPPLSMPDHLLDEGLD
MAB_4207|M.abscessus_ATCC_1997 LEPDAALTKSIAAEALSQGVLILTCGTFGNVIRLLPPLVIGDDLLDEGIT
MMAR_2465|M.marinum_M --------HAKAAEVAAREAGYLVNGAAPNVVRLAPPLVITEPQLEGFVA
MUL_1647|M.ulcerans_Agy99 --------HAKAAEVAAREVGYLVNGAAPNVVRLAPPLVITEPQLEGFVA
TH_3529|M.thermoresistible__bu --------QAKAAEAAARDAGFLVNAAAPEVIRLAPPLIITETQIDEFLA
Mvan_2918|M.vanbaalenii_PYR-1 GDRDPRLAAAVVYRAWELGAVVYYVG--GNVLEITPPLVLTESQAAQAAE
. . :::.: *** : :
Mb2620|M.bovis_AF2122/97 IVCAILADL----------------
Rv2589|M.tuberculosis_H37Rv IVCAILADL----------------
MAV_3470|M.avium_104 ILGGLLADL----------------
MLBr_00485|M.leprae_Br4923 ILSRILGDF----------------
Mflv_3818|M.gilvum_PYR-GCK ILELILRDL----------------
MSMEG_0581|M.smegmatis_MC2_155 ILAAVFAEVK---------------
MAB_4207|M.abscessus_ATCC_1997 ALSDIIRAKASHQ------------
MMAR_2465|M.marinum_M ALPGILDTAGASA------------
MUL_1647|M.ulcerans_Agy99 ALPGILDNAGASA------------
TH_3529|M.thermoresistible__bu ALPGVLDTAKEAS------------
Mvan_2918|M.vanbaalenii_PYR-1 IIGAAIGDAAAGKIDAEEVAKYAGW
: :