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SALEQSRHLATAIPGPRSCELIARKSAAVARGVGTTMPVYAARAFGGIVEDVDGNRLIDLGSGIAVTTIG NASPKVVERAAEQLHKFTHTCFMVTPYEGYVAVAEALNRLTPGDGDKRTALFNSGSEAVENAVKIARSYT RKQAVVSFDHAYHGRTNLTMALTAKSMPYKHGFGPFAPEIYRAPLSYPFRDAEFGKELATDGELAARRAI TVIDKQVGADNLAAVIIEPIQGEGGFIVPAEGFLPTLLEWCHANGVVFIADEVQTGFARTGAMFACEHEG IVPDLIVTAKGIADGMPLSAVTGRAEIMDAPHVSGLGGTYGGNPVACAAALATIETIESDGLVARAAQIE TLMKDKLGRLQAEDDRIGDVRGRGAMIAVELVKPGTLEPDPELTKNLLAAAHRAGVIVLSCGTFGNVLRF LPPLAISDELLLEGLDVLELILRDL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2581 | - | - | 100% (446) | 4-aminobutyrate aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_1858 | - | e-153 | 61.56% (437) | 4-aminobutyrate aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_2918 | - | 8e-60 | 33.64% (428) | aminotransferase class-III |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2620 | gabT | 0.0 | 77.28% (449) | 4-aminobutyrate aminotransferase |
| M. gilvum PYR-GCK | Mflv_3818 | - | 0.0 | 91.11% (450) | 4-aminobutyrate aminotransferase |
| M. tuberculosis H37Rv | Rv2589 | gabT | 0.0 | 77.28% (449) | 4-aminobutyrate aminotransferase |
| M. leprae Br4923 | MLBr_00485 | gabT | 0.0 | 76.40% (445) | 4-aminobutyrate aminotransferase |
| M. abscessus ATCC 19977 | MAB_4207 | - | 1e-162 | 65.76% (441) | 4-aminobutyrate aminotransferase |
| M. marinum M | MMAR_2118 | gabT | 0.0 | 76.46% (446) | 4-aminobutyrate aminotransferase GabT |
| M. avium 104 | MAV_3470 | gabT | 0.0 | 75.28% (449) | 4-aminobutyrate aminotransferase |
| M. smegmatis MC2 155 | MSMEG_2959 | gabT | 0.0 | 85.36% (444) | 4-aminobutyrate aminotransferase |
| M. thermoresistible (build 8) | TH_1978 | - | 4e-46 | 33.10% (432) | PROBABLE AMINOTRANSFERASE |
| M. ulcerans Agy99 | MUL_1723 | gabT | 0.0 | 76.01% (446) | 4-aminobutyrate aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2581|M.vanbaalenii_PYR-1 ----MSALEQSRHLATAIPGPRSCELIARKSAAVARGVGTTMPVYAARAF
Mflv_3818|M.gilvum_PYR-GCK ----MSALEQSRHLATAIPGPRSVELASRKNTAVSRGVGTTMPVYAARAF
MSMEG_2959|M.smegmatis_MC2_155 ----MSHPEQSRHLATAIPGPRSQALIDRKGTAVARGVGTTMPVYAVRAG
Mb2620|M.bovis_AF2122/97 ----MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVARAG
Rv2589|M.tuberculosis_H37Rv ----MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVARAG
MLBr_00485|M.leprae_Br4923 ----MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVTRAA
MAV_3470|M.avium_104 ----MARLEQTRRLVTEIPGPASLELSKRRAAAVSHAVNVSVPVFVARAG
MMAR_2118|M.marinum_M ----MASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPVFVVRAG
MUL_1723|M.ulcerans_Agy99 ----MASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPVFVVRAG
MAB_4207|M.abscessus_ATCC_1997 MTDITYRLAQKRTIVTPLPGPRSGALAERRRAAVSAGVGSTAPVYAVDAD
TH_1978|M.thermoresistible__bu -----------------MSTDRAAQADRHLWGHFARHGPGVTPPIIVRGD
:. : : .. * . .
Mvan_2581|M.vanbaalenii_PYR-1 GGIVEDVDGNRLIDLGSGIAVTTIGNASPKVVERAAEQLHKFTHTCFMVT
Mflv_3818|M.gilvum_PYR-GCK GGIVEDVDGNRLIDLGSGIAVTTVGNASPRVVAAVAEQAAEFTHTCFMVT
MSMEG_2959|M.smegmatis_MC2_155 GGIVEDVDGNRLIDLGSGIAVTTVGNSAPKVVEAVRSQVGDFTHTCFMVT
Mb2620|M.bovis_AF2122/97 GGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCFMVT
Rv2589|M.tuberculosis_H37Rv GGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCFMVT
MLBr_00485|M.leprae_Br4923 GGVIEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTHTCFIIT
MAV_3470|M.avium_104 GGIVEDVDGNRLIDLGSGIAVTTIGNSAPRVVDAVRAQVAEFTHTCFMVT
MMAR_2118|M.marinum_M GGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTHTCFMVT
MUL_1723|M.ulcerans_Agy99 GGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTHTCFMVI
MAB_4207|M.abscessus_ATCC_1997 GGVIVDADGNSFIDLGAGIAVTTVGASHPAVAAAIADQATHFTHTCFMVT
TH_1978|M.thermoresistible__bu GVTIWDDHGRRYLDGLSGLFVVQAGHGRAELAEAAARQAGQLAYFPLWSY
* : * .*. :* :*: *. * . . :. * .::: :
Mvan_2581|M.vanbaalenii_PYR-1 PYEGYVAVAEALNRLTPGDGDKRTALFNSGSEAVENAVKIARSYT-----
Mflv_3818|M.gilvum_PYR-GCK PYEGYVAVAEALNRLTPGDGDKRSALFNSGSEAVENAVKIARTFT-----
MSMEG_2959|M.smegmatis_MC2_155 PYEGYVAVCEQLNRLTPVRGDKRSALFNSGSEAVENAVKIARSHT-----
Mb2620|M.bovis_AF2122/97 PYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYT-----
Rv2589|M.tuberculosis_H37Rv PYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYT-----
MLBr_00485|M.leprae_Br4923 PYEEYVAVTEQLNRITPGSGEKRSVLFNSGAEAVENSIKVARSYT-----
MAV_3470|M.avium_104 PYESYVAVAETLNRITPGAGEKRSVLFNSGAEAVENAVKVARAYT-----
MMAR_2118|M.marinum_M PYEQYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAHT-----
MUL_1723|M.ulcerans_Agy99 PYEHYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAHT-----
MAB_4207|M.abscessus_ATCC_1997 PYEGYVQVAELLNALTPGDHDKRTALFNSGAEAVENAIKVARLAT-----
TH_1978|M.thermoresistible__bu ATPPAIELAERIAHYAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKLTGK
. : : * : :* * : ..*.****.: *:*:
Mvan_2581|M.vanbaalenii_PYR-1 -RKQAVVSFDHAYHGRTNLTMALTAKSMPYKHGFGPFAPEIYRAPLSYPF
Mflv_3818|M.gilvum_PYR-GCK -RKQAVVSFDHAYHGRTNLTMALTAKSMPYKHGFGPFAPEIYRAPMSYPF
MSMEG_2959|M.smegmatis_MC2_155 -HKPAVVAFDHAYHGRTNLTMALTAKVMPYKDGFGPFAPEIYRAPLSYPF
Mb2620|M.bovis_AF2122/97 -GKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPY
Rv2589|M.tuberculosis_H37Rv -GKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPY
MLBr_00485|M.leprae_Br4923 -RKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPY
MAV_3470|M.avium_104 -RKPAVVAFDHAYHGRTNLAMALTAKSMPYKGGFGPFAPEIYRAPLSYPY
MMAR_2118|M.marinum_M -RKQAVVAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPY
MUL_1723|M.ulcerans_Agy99 -RKQAVVAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPY
MAB_4207|M.abscessus_ATCC_1997 -GRPAVVAFDNAYHGRTNLTMALTAKSMPYKSQFGPFAPEVYRMPASYPL
TH_1978|M.thermoresistible__bu PGKHKVVSRAVAYHGTPQGALAITGLPM-FKAPFEPLTPGGFRVPNTNFY
: **: **** .: ::*:*. * :* * *::* :* * :
Mvan_2581|M.vanbaalenii_PYR-1 RDAEFG-KELATDGELAARRAITVIDKQVGADNLAAVIIEPIQGEGGFIV
Mflv_3818|M.gilvum_PYR-GCK RDAEFGGKELATDGELAARRAITVIDKQVGAGNLAAVIIEPIQGEGGFIV
MSMEG_2959|M.smegmatis_MC2_155 RDAEFG-KELATDGELAAKRAITVIDKQIGADNLAAVVIEPIQGEGGFIV
Mb2620|M.bovis_AF2122/97 RDGLLD-KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIV
Rv2589|M.tuberculosis_H37Rv RDGLLD-KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIV
MLBr_00485|M.leprae_Br4923 RDGLLN-KDLATDGKLAGARAINVIEKQVGADDLAAVIIEPIQGEGGFIV
MAV_3470|M.avium_104 RDGLLD-KELATDGEKAAARAINIIDGQIGADSLAAVIIEPIQGEGGFIV
MMAR_2118|M.marinum_M RDNLLD-KDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIV
MUL_1723|M.ulcerans_Agy99 RDNLLD-KDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIV
MAB_4207|M.abscessus_ATCC_1997 RD------EPGLTGEEAARRAISRIETQIGAQSLAAIIIEPIQGEGGFIV
TH_1978|M.thermoresistible__bu RAPAPYRDDEKAFGRYCADRIAETIEFE-GPDTVAAVVLEPVQNAGGCIP
* : *. .. * *: : *. :**:::**: . ** *
Mvan_2581|M.vanbaalenii_PYR-1 PAEGFLPTLLEWCHANGVVFIADEVQTGFARTGAMFACEHEG---IVPDL
Mflv_3818|M.gilvum_PYR-GCK PAEGFLPTLLDWCRANDVVFIADEVQTGFARTGAMFACEHEGPDGLVPDL
MSMEG_2959|M.smegmatis_MC2_155 PADGFLPTLLDWCRKNDVVFIADEVQTGFARTGAMFACEHEG---IDPDL
Mb2620|M.bovis_AF2122/97 PAEGFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDL
Rv2589|M.tuberculosis_H37Rv PAEGFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDL
MLBr_00485|M.leprae_Br4923 PAEGFLATLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDG---IVPDL
MAV_3470|M.avium_104 PAEGFLPTLLDWCRRNDVLFIADEVQTGFARSGAMFACEHEGPNGLEPDL
MMAR_2118|M.marinum_M PADGFLPALQRWCRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDL
MUL_1723|M.ulcerans_Agy99 PADGFLPALQRWSRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDL
MAB_4207|M.abscessus_ATCC_1997 PAPGFLATLTAWASENGVVFIADEVQTGFARTGAWFASEHEG---IVPDI
TH_1978|M.thermoresistible__bu PPPGYFERVREICDTYDVLLISDEVICAFGRIGSMFACDDFG---YQPDI
*. *:: : . *::*:*** .*.* *: **.:. . **:
Mvan_2581|M.vanbaalenii_PYR-1 IVTAKGIADGMPLSAVTGRAEIMDAPHVSG-----LGGTYGGNPVACAAA
Mflv_3818|M.gilvum_PYR-GCK IVTAKGIAGGMPLSAVTGRADIMDAPHVSG-----LGGTYGGNPVACAAA
MSMEG_2959|M.smegmatis_MC2_155 IVTAKGIAGGLPLSAVTGRAEIMDSPHVSG-----LGGTYGGNPIACAAA
Mb2620|M.bovis_AF2122/97 ICTAKGIADGLPLSAVTGRAEIMNAPHVGG-----LGGTFGGNPVACAAA
Rv2589|M.tuberculosis_H37Rv ICTAKGIADGLPLSAVTGRAEIMNAPHVGG-----LGGTFGGNPVACAAA
MLBr_00485|M.leprae_Br4923 ICTAKGIADGLPLAAVTGRAEIMNAPHVSG-----LGGTFGGNPVACAAA
MAV_3470|M.avium_104 ICTAKAIADGLPLSAVTGRAQIMDAPHVGG-----LGGTFGGNPLACAAA
MMAR_2118|M.marinum_M IVTAKGIADGFPLSAVTGRAEIMDAPHTSG-----LGGTFGGNPVACAAA
MUL_1723|M.ulcerans_Agy99 IVTAKGIADGFPLSAVTGRAEIMDAPHTSG-----LGGTFGGNPVACAAA
MAB_4207|M.abscessus_ATCC_1997 VTMAKGIAGGMPLSAVTGRAELMDAVYAGG-----LGGTYGGNPVTCAAA
TH_1978|M.thermoresistible__bu ITCAKGLTSGYAPLGAMIATDRLFEPFADGKTVFPHGYTFGGHPVSAAVA
: **.::.* . .. :: : ...* * *:**:*::.*.*
Mvan_2581|M.vanbaalenii_PYR-1 LATIETIESDGLVARAAQIETLMKDKLGRLQAEDDRIGDVRGRGAMIAVE
Mflv_3818|M.gilvum_PYR-GCK LATIETIESDNLVARAAQIEALMKDRLGRMQAEDDRIGDVRGRGAMIAVE
MSMEG_2959|M.smegmatis_MC2_155 LATIETIESEGLVARAQQIEKIMKDRLGRLQAEDDRIGDVRGRGAMIAME
Mb2620|M.bovis_AF2122/97 LATIATIESDGLIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVE
Rv2589|M.tuberculosis_H37Rv LATIATIESDGLIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVE
MLBr_00485|M.leprae_Br4923 LATITTIENDGLIQRAQQIERLITDRLLRLQDADDRIGDVRGRGAMIAVE
MAV_3470|M.avium_104 LATIETIESDGLIERARQLERLITEPLLRLQARDDRIGDVRGRGAMIAIE
MMAR_2118|M.marinum_M LATIETIERDGMVERARQIERLVMDRLLRLQAADDRLGDVRGRGAMIAME
MUL_1723|M.ulcerans_Agy99 LATIETIERDGMVERARQIERLVMDRLLRLQAADDRLGDVRGRGAMIAME
MAB_4207|M.abscessus_ATCC_1997 VAALGVMRELDLPARARAIEASVTSRLSALAEEVDIIGEVRGRGAMLAIE
TH_1978|M.thermoresistible__bu LANLDIFEREGLNDRVRTLSPLLRATLERLYELP-IVGDVRGEGYFFAVE
:* : :. .: *. :. : * : :*:***.* ::*:*
Mvan_2581|M.vanbaalenii_PYR-1 LVKPGT------LEPDPELTKNLLAAAHRAGVIVLSCGTFGNVLRFLPPL
Mflv_3818|M.gilvum_PYR-GCK LVKSGT------LEPDPELTRKLLTAAHAAGVIVLSCGTFGNVLRFLPPL
MSMEG_2959|M.smegmatis_MC2_155 LVKAGT------TEPDADLTKALCAGAHAAGVIVLSCGTYGNVVRFLPPL
Mb2620|M.bovis_AF2122/97 LVKSGT------TEPDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPL
Rv2589|M.tuberculosis_H37Rv LVKSGT------TEPDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPL
MLBr_00485|M.leprae_Br4923 LVKSGT------AEPDPELTEKVATAAHATGVIILTCGMFGNIIRLLPPL
MAV_3470|M.avium_104 LVKSGT------AEPDKDLTQRLSVAAHAAGVIVLTCGMFGNIIRLLPPL
MMAR_2118|M.marinum_M LVKSGT------AEPDAALTQKLAAAAHAAGVIVLTCGMFGNVIRLLPPL
MUL_1723|M.ulcerans_Agy99 LVKSGT------AEPDAALTQKLAAAAHAAGVIVLTCGMFGNVIRLLPPL
MAB_4207|M.abscessus_ATCC_1997 IVKPGT------LEPDAALTKSIAAEALSQGVLILTCGTFGNVIRLLPPL
TH_1978|M.thermoresistible__bu LVQDKAGRQPFSAEESARLVAHLNRALLDAGLYCRADNRGDTVVQVAPPL
:*: : * . *. : *: : . ..:::. ***
Mvan_2581|M.vanbaalenii_PYR-1 AISDELLLEGLDVLELILRDL----
Mflv_3818|M.gilvum_PYR-GCK AISDDLLLEGLDILELILRDL----
MSMEG_2959|M.smegmatis_MC2_155 SIGDDLLNEGLDVLEEVLRGA----
Mb2620|M.bovis_AF2122/97 TIGDELLSEGLDIVCAILADL----
Rv2589|M.tuberculosis_H37Rv TIGDELLSEGLDIVCAILADL----
MLBr_00485|M.leprae_Br4923 TISDELLAEGLDILSRILGDF----
MAV_3470|M.avium_104 TISDELLAEGIDILGGLLADL----
MMAR_2118|M.marinum_M TISDELLSEGLDILCQILADL----
MUL_1723|M.ulcerans_Agy99 TISDELLSEGLDILCQILADL----
MAB_4207|M.abscessus_ATCC_1997 VIGDDLLDEGITALSDIIRAKASHQ
TH_1978|M.thermoresistible__bu ISGPAEFDAMHDILRTVLKDAPNHV
. : : ::