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MTHTEDTRARWEAVMMNNYGTPPVALASGEGAVVTDVDGKNYVDLLGGIAVNILGHRHPAVIEAVTQQMS TLGHTSNLYATEPTNALAEELVTLLGAEAPARVFFCNSGTEANEAAFKLSRLTGRTKLVAAQEGFHGRTM GSLALTGQPAKQAPFEPLPGYVTHVPYGDIDALAAAVDDETAAVFLEPIMGESGVVVPPEGYLLAAREIT ARHGALLVLDEVQTGIGRTGAFYAHQHDGITPDVVTLAKGLGGGLPIGACLAIGPAAELLTPGLHGSTFG GNPVCAAAALAVLRVVASEGLVCRAETLGKTFKQGVESLSHPLIDHVRGRGLLLGIVLAGPHAKAAEVAA REVGYLVNGAAPNVVRLAPPLVITEPQLEGFVAALPGILDNAGASA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1647 | argD | - | 100% (396) | acetylornithine aminotransferase |
| M. ulcerans Agy99 | MUL_1243 | rocD | 5e-62 | 35.24% (403) | ornithine aminotransferase RocD1 and RocD2 |
| M. ulcerans Agy99 | MUL_2791 | - | 2e-48 | 33.33% (441) | hypothetical protein MUL_2791 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1683 | argD | 0.0 | 83.38% (391) | acetylornithine aminotransferase |
| M. gilvum PYR-GCK | Mflv_3527 | argD | 1e-178 | 79.53% (386) | acetylornithine aminotransferase |
| M. tuberculosis H37Rv | Rv1655 | argD | 0.0 | 83.38% (391) | acetylornithine aminotransferase |
| M. leprae Br4923 | MLBr_01409 | argD | 0.0 | 79.95% (389) | acetylornithine aminotransferase |
| M. abscessus ATCC 19977 | MAB_2339 | argD | 1e-166 | 75.32% (389) | acetylornithine aminotransferase |
| M. marinum M | MMAR_2465 | argD | 0.0 | 98.99% (396) | acetylornithine aminotransferase ArgD |
| M. avium 104 | MAV_3115 | argD | 0.0 | 80.15% (408) | acetylornithine aminotransferase |
| M. smegmatis MC2 155 | MSMEG_3773 | argD | 1e-173 | 76.62% (385) | acetylornithine aminotransferase |
| M. thermoresistible (build 8) | TH_3529 | - | 1e-174 | 77.81% (383) | PUTATIVE aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_3311 | argD | 1e-179 | 80.83% (386) | acetylornithine aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3527|M.gilvum_PYR-GCK --MTGEHRPGLLDRWSAVMMNNYGTPPLALASGQGAVVTDADGKSYIDLL
Mvan_3311|M.vanbaalenii_PYR-1 --MT-----ELLNRWSAVMMNNYGTPPLALAGGDGAVVTDVDGKAYLDLL
MSMEG_3773|M.smegmatis_MC2_155 --------MTLQSRWEAVMMNNYGTPPLSLVSGEGAVVTDADGREYLDLL
TH_3529|M.thermoresistible__bu -VSGSKGRHTLLDRWQGVMMNNYGTPPLALVSGDGAVVTDADGKSYLDLL
MUL_1647|M.ulcerans_Agy99 ----MTHTEDTRARWEAVMMNNYGTPPVALASGEGAVVTDVDGKNYVDLL
MMAR_2465|M.marinum_M ----MTHTEDTRARWEAVMMNNYGTPPVALASGEGAVVTDVDGKNYVDLL
Mb1683|M.bovis_AF2122/97 MTGASTTTATMRQRWQAVMMNNYGTPPIALASGDGAVVTDVDGRTYIDLL
Rv1655|M.tuberculosis_H37Rv MTGASTTTATMRQRWQAVMMNNYGTPPIALASGDGAVVTDVDGRTYIDLL
MLBr_01409|M.leprae_Br4923 MTPTQTNTATMQQRWETVMMNNYGTPPIVLASGNGAVVTDVDSNTYLDLL
MAV_3115|M.avium_104 ---MVTNTDALRRRWEAVMMHNYGTPPVALASGEGAVVTDVDGNTYLDLL
MAB_2339|M.abscessus_ATCC_1997 MTEAPDSTSRAQQRWEHVMMNNYGTPPIVLAEGEGAVVTDVDGKRYLDLL
**. ***:******: *. *:******.*.. *:***
Mflv_3527|M.gilvum_PYR-GCK GGIAVNVLGHRHPAVIEAVTRQMNTLGHTSNLYATEPGVALAEALVDLLG
Mvan_3311|M.vanbaalenii_PYR-1 GGIAVNVLGHRHPAVIEAVTRQMNTLGHTSNLYATEPGVALAESLVGLLG
MSMEG_3773|M.smegmatis_MC2_155 GGIAVNLLGHRHPAVIEAVTTQLDTLGHTSNLYATEPGIALAEALVGQLG
TH_3529|M.thermoresistible__bu GGIAVNILGHRHPAVIEAVTRQLNTLGHTSNLYATEPGVALAEALVGHLG
MUL_1647|M.ulcerans_Agy99 GGIAVNILGHRHPAVIEAVTQQMSTLGHTSNLYATEPTNALAEELVTLLG
MMAR_2465|M.marinum_M GGIAVNILGHRHPAVIEAVTQQMSTLGHTSNLYATEPTIALAEELVTLLG
Mb1683|M.bovis_AF2122/97 GGIAVNVLGHRHPAVIEAVTRQMSTLGHTSNLYATEPGIALAEELVALLG
Rv1655|M.tuberculosis_H37Rv GGIAVNVLGHRHPAVIEAVTRQMSTLGHTSNLYATEPGIALAEELVALLG
MLBr_01409|M.leprae_Br4923 GGIAVNVLGHRHPAVIEAVTHQITTLGHTSNLYATEPSITLAEELVALLG
MAV_3115|M.avium_104 GGIAVNVLGHRHPAIIEAVTKQLSTLGHTSNLYATEPSLALAEELVALLG
MAB_2339|M.abscessus_ATCC_1997 GGIAVNVLGHRNQSVIDAVTQQLSTLGHTSNLYATGPAIELSEALVARLG
******:****: ::*:*** *: *********** * *:* ** **
Mflv_3527|M.gilvum_PYR-GCK VPAK----------------VFFCNSGTEANEVAFKITRLTGRTKLVAAQ
Mvan_3311|M.vanbaalenii_PYR-1 APAK----------------AFFCNSGTEANEAAFKITRLTGRTKVVAAE
MSMEG_3773|M.smegmatis_MC2_155 TQAR----------------VFFCNSGTEANEVAFKITRLTGKTKIVAAE
TH_3529|M.thermoresistible__bu APAR----------------VFFCNSGAEANEVAFKISRLTGRTKVVAAE
MUL_1647|M.ulcerans_Agy99 AEAP--------------ARVFFCNSGTEANEAAFKLSRLTGRTKLVAAQ
MMAR_2465|M.marinum_M AEAP--------------ARVFFCNSGTEANEAAFKLSRLTGRTKLVAAQ
Mb1683|M.bovis_AF2122/97 ADQR--------------TRVFFCNSGAEANEAAFKLSRLTGRTKLVAAH
Rv1655|M.tuberculosis_H37Rv ADQR--------------TRVFFCNSGAEANEAAFKLSRLTGRTKLVAAH
MLBr_01409|M.leprae_Br4923 ADTQ--------------TRVFFCNSGTEANELAFKLSRLTGRTKLVAAQ
MAV_3115|M.avium_104 AGHEPAGHESGGTESAGTARVFFCNSGTEANEVAFKLSRLTGRTKLVAAQ
MAB_2339|M.abscessus_ATCC_1997 VPGR----------------VFLCNSGTEANEAAFKLTRLTGRTKVVAAE
. .*:****:**** ***::****:**:***.
Mflv_3527|M.gilvum_PYR-GCK GAFHGRTMGSLALTGQPAKQAPFEPLPGDVTHVPYGDVDALRAVVDSETA
Mvan_3311|M.vanbaalenii_PYR-1 GAFHGRTMGSLALTGQPSKRAPFEPLPGGVTHVPYGDIDELRRVVDDQTA
MSMEG_3773|M.smegmatis_MC2_155 GAFHGRTMGSLALTGQPSKQAPFEPLPGNVMHVPYGDVAALEAAVDDQTA
TH_3529|M.thermoresistible__bu GGFHGRTMGALALTGQPSKREPFEPLPGDVIHVPYGDAGALERAVDDTTA
MUL_1647|M.ulcerans_Agy99 EGFHGRTMGSLALTGQPAKQAPFEPLPGYVTHVPYGDIDALAAAVDDETA
MMAR_2465|M.marinum_M EGFHGRTMGSLALTGQPAKQAPFEPLPGYVTHVPYGDIDALAAAVDDETA
Mb1683|M.bovis_AF2122/97 DAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYGDVDALAAAVDDHTA
Rv1655|M.tuberculosis_H37Rv DAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYGDVDALAAAVDDHTA
MLBr_01409|M.leprae_Br4923 AAFHGRTMGSLALTGQPAKQAAFEPLPGHVTHVPYGQVDALAAAVDNDTA
MAV_3115|M.avium_104 EAFHGRTMGSLALTGQPSKQAPFAPLPGDVTHVPYGDTEALAAAVDDGTA
MAB_2339|M.abscessus_ATCC_1997 GAFHGRTMGSLALTGQPAKQAPFEPLPAGVLHVPYGDLAAIEAAVDGDTA
.*******:*******:*: .* ***. * ** **: : .**. **
Mflv_3527|M.gilvum_PYR-GCK AVFLEPIMGEGGVVVPPAGYLVAAREITAEHGALLILDEVQTGVGRTGAF
Mvan_3311|M.vanbaalenii_PYR-1 AVFLEPIMGEGGVVVPPAGYLVAAREITAAHGALLVLDEVQTGVGRTGAF
MSMEG_3773|M.smegmatis_MC2_155 AVFLEPIMGEGGVVVPPAGYLVAAREITSKHGALLVLDEVQTGVGRTGAF
TH_3529|M.thermoresistible__bu AVFLEPIMGEGGVVVPPAGYLAAAREVTARHGALLVLDEVQTGIGRTGTF
MUL_1647|M.ulcerans_Agy99 AVFLEPIMGESGVVVPPEGYLLAAREITARHGALLVLDEVQTGIGRTGAF
MMAR_2465|M.marinum_M AVFLEPIMGESGVVVPPEGYLLAAREITARHGALLVLDEVQTGIGRTGAF
Mb1683|M.bovis_AF2122/97 AVFLEPIMGESGVVVPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAF
Rv1655|M.tuberculosis_H37Rv AVFLEPIMGESGVVVPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAF
MLBr_01409|M.leprae_Br4923 AVFLEPIMGESGVIVPPEGYLAAARDITTRHGALLVIDEVQTGIGRTGAF
MAV_3115|M.avium_104 AVFLEPIMGESGVVVPPEGYLAAARDITARHGALLVLDEVQTGMGRTGTF
MAB_2339|M.abscessus_ATCC_1997 AVFLEPIMGEGGVVVPPEGYLAGVREITARHGALLVLDEVQTGIGRTGTF
**********.**:*** *** ..*::*: :****::******:****:*
Mflv_3527|M.gilvum_PYR-GCK FAHRHDGITPDVVTLAKGLGGGLPIGACLAIGDTAELLTPGLHGSTFGGN
Mvan_3311|M.vanbaalenii_PYR-1 YAHQHDGITPDIVTLAKGLGGGLPIGACLAIGDTADLLTPGLHGSTFGGN
MSMEG_3773|M.smegmatis_MC2_155 FAHQHDGIVPDVVTMAKGLGGGLPIGACLAVGATGDLLTPGLHGSTFGGN
TH_3529|M.thermoresistible__bu FAHQHDGITPDVVTLAKGLGGGLPIGACLAVGPAGDLLTPGMHGSTFGGN
MUL_1647|M.ulcerans_Agy99 YAHQHDGITPDVVTLAKGLGGGLPIGACLAIGPAAELLTPGLHGSTFGGN
MMAR_2465|M.marinum_M YAHQHDGITPDVVTLAKGLGGGLPIGACLAIGPAAELLTPGLHGSTFGGN
Mb1683|M.bovis_AF2122/97 FAHQHDGITPDVVTLAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGN
Rv1655|M.tuberculosis_H37Rv FAHQHDGITPDVVTLAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGN
MLBr_01409|M.leprae_Br4923 FAHQHDSITPDVVTLAKGLGGGLPIGAFLATGPAAELLTLGLHGSTFGGN
MAV_3115|M.avium_104 FAHQHDGITPDVVTLAKGLGGGLPIGACLAVGPAADLLTPGLHGSTFGGN
MAB_2339|M.abscessus_ATCC_1997 FAHQQAGITPDVVTLAKGLGGGLPIGACIATGAAADLLTPGMHGSTFGGN
:**:: .*.**:**:************ :* * :.:*** *:********
Mflv_3527|M.gilvum_PYR-GCK PVCTAAALAVLKVLADDGLVERADILGKTIAHGIEALNHPLVDHVRGLGL
Mvan_3311|M.vanbaalenii_PYR-1 PVCTAAALAVLKVLADEGLVERADVLGKTIAHGVESLGHPLVDHVRGRGL
MSMEG_3773|M.smegmatis_MC2_155 PVCTAAGLAVLKTLAAEDLVARAGVLGKTLSHGIEELGHPLVDKVRGKGL
TH_3529|M.thermoresistible__bu PVCTAAAVAVLGALAEGDLINRADVLGKKLSHGIEELRHPLVDHVRGRGL
MUL_1647|M.ulcerans_Agy99 PVCAAAALAVLRVVASEGLVCRAETLGKTFKQGVESLSHPLIDHVRGRGL
MMAR_2465|M.marinum_M PVCAAAALAVLRVVASEGLVRRAETLGKTFKQGVESLSHPLIDHVRGRGL
Mb1683|M.bovis_AF2122/97 PVCAAAALAVLRVLASDGLVRRAEVLGKSLRHGIEALGHPLIDHVRGRGL
Rv1655|M.tuberculosis_H37Rv PVCAAAALAVLRVLASDGLVRRAEVLGKSLRHGIEALGHPLIDHVRGRGL
MLBr_01409|M.leprae_Br4923 PVCTAAALAVLRVLATQGLVRRAEVLGDSMRIGIESLSHPLIDQVRGRGL
MAV_3115|M.avium_104 PVCAAAALAVLRVLASENLVRHAEVLGKSLHQGIEGLGHPLVDHVRGRGL
MAB_2339|M.abscessus_ATCC_1997 PVCVAAALAVLRVLDEQDLVDHAAAAGKSLSHSVEELNHPLVDRVRGAGL
***.**.:*** .: .*: :* *..: .:* * ***:*:*** **
Mflv_3527|M.gilvum_PYR-GCK LRGIVLTADAAKSVEAEARDAGFLVNAAAADVIRLAPPLVITDAEVESFL
Mvan_3311|M.vanbaalenii_PYR-1 LRGIVLTADAAKPVETAAREAGFLVNAAAPAIVRLAPPLVITEAQVETFL
MSMEG_3773|M.smegmatis_MC2_155 LQGIVLTVPSAKAVETAARDAGFLVNAAAPEVVRLAPPLIITEGQIEAFI
TH_3529|M.thermoresistible__bu LCGVVLNAPQAKAAEAAARDAGFLVNAAAPEVIRLAPPLIITETQIDEFL
MUL_1647|M.ulcerans_Agy99 LLGIVLAGPHAKAAEVAAREVGYLVNGAAPNVVRLAPPLVITEPQLEGFV
MMAR_2465|M.marinum_M LLGIVLAGPHAKAAEVAAREAGYLVNGAAPNVVRLAPPLVITEPQLEGFV
Mb1683|M.bovis_AF2122/97 LLGIALTAPHAKDAEATARDAGYLVNAAAPDVIRLAPPLIIAEAQLDGFV
Rv1655|M.tuberculosis_H37Rv LLGIALTAPHAKDAEATARDAGYLVNAAAPDVIRLAPPLIIAEAQLDGFV
MLBr_01409|M.leprae_Br4923 LLGIVLTAPRAKDIEKAARDAGFLVNATAPEVIRLAPPLIITESQIDSFI
MAV_3115|M.avium_104 LCGVVLTAPRAKDAEAAAREAGFLVNAAAPGVIRLAPPLIVTEAQIDGFI
MAB_2339|M.abscessus_ATCC_1997 LLGIVLTEQRAKAAETAAREAGFLVNAAAPDVLRLAPPLIITDEQIGEFV
* *:.* ** * **:.*:***.:*. ::******:::: :: *:
Mflv_3527|M.gilvum_PYR-GCK AALPRILDKAAQS-----
Mvan_3311|M.vanbaalenii_PYR-1 SALPAILDKAAQS-----
MSMEG_3773|M.smegmatis_MC2_155 TALPAVLDTAAEDS----
TH_3529|M.thermoresistible__bu AALPGVLDTAKEAS----
MUL_1647|M.ulcerans_Agy99 AALPGILDNAGASA----
MMAR_2465|M.marinum_M AALPGILDTAGASA----
Mb1683|M.bovis_AF2122/97 AALPAILDRAVGAP----
Rv1655|M.tuberculosis_H37Rv AALPAILDRAVGAP----
MLBr_01409|M.leprae_Br4923 TALPGILDASIAELGKKA
MAV_3115|M.avium_104 AALPGILDRAAA------
MAB_2339|M.abscessus_ATCC_1997 TALPGILDTAAEQEQA--
:*** :** :