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MTGILEGKRILVTGIITDSSIAFYIAKVAQEAGAEVICTGFNRLRLIERILERLPSKPPLLELDVQDEKH LDTLADRITEVIGDGNKLDGVVHSIGFMPQTGMGINPFFDAPYEDVAKGIHISAYSYASLAKAVLPIMNP GGGIVGMDFDPTRAMPAYNWMTVAKSALESVNRFVAREAGKVGVRSNLVAAGPIRTLAMSAIVGGALGEE AGAQMQLLAEGWDQRAPLGWNMKDPTPVAKTVCALLSDWLPATTGTVIFADGGASTQLL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2753 | - | - | 100% (269) | enoyl-(acyl carrier protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_5228 | - | 2e-09 | 23.98% (196) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5918 | - | 4e-08 | 26.97% (267) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1520 | inhA | 1e-133 | 85.50% (269) | enoyl-(acyl carrier protein) reductase |
| M. gilvum PYR-GCK | Mflv_3657 | - | 1e-140 | 91.35% (266) | enoyl-(acyl carrier protein) reductase |
| M. tuberculosis H37Rv | Rv1484 | inhA | 1e-133 | 85.50% (269) | enoyl-(acyl carrier protein) reductase |
| M. leprae Br4923 | MLBr_01806 | inhA | 1e-133 | 85.50% (269) | enoyl-(acyl carrier protein) reductase |
| M. abscessus ATCC 19977 | MAB_2722c | - | 1e-132 | 85.13% (269) | enoyl-(acyl carrier protein) reductase |
| M. marinum M | MMAR_2290 | inhA | 1e-134 | 85.13% (269) | enoyl- |
| M. avium 104 | MAV_3294 | - | 1e-133 | 84.39% (269) | enoyl-(acyl carrier protein) reductase |
| M. smegmatis MC2 155 | MSMEG_3151 | - | 1e-139 | 89.96% (269) | enoyl-(acyl carrier protein) reductase |
| M. thermoresistible (build 8) | TH_1379 | inhA | 1e-131 | 85.24% (271) | NADH-DEPENDENT ENOYL- |
| M. ulcerans Agy99 | MUL_1492 | inhA | 1e-134 | 85.13% (269) | enoyl-(acyl carrier protein) reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2753|M.vanbaalenii_PYR-1 MTGILEGKRILVTGIITDSSIAFYIAKVAQEAGAEVICTGFNRLRLIERI
Mflv_3657|M.gilvum_PYR-GCK MT-LLQGKRILVTGIITDSSIAFHIAKVAQEAGAELVLTGFDRMKLIQRI
MSMEG_3151|M.smegmatis_MC2_155 MTGLLEGKRILVTGIITDSSIAFHIAKVAQEAGAELVLTGFDRLKLVKRI
MAB_2722c|M.abscessus_ATCC_199 MAGLLEGKRILVTGIITDSSIAFHIAKVAQEQGAELVLTGFDRLRLIERI
Mb1520|M.bovis_AF2122/97 MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRI
Rv1484|M.tuberculosis_H37Rv MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRI
MMAR_2290|M.marinum_M MAGLLEGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRMRLIQRI
MUL_1492|M.ulcerans_Agy99 MAGLLEGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRMRLIQRI
MLBr_01806|M.leprae_Br4923 MAGLLEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRI
MAV_3294|M.avium_104 MAGLLDGKRILVTGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRI
TH_1379|M.thermoresistible__bu MAGFLEGKRILVTGIITDSSIAFHIARVAQEAGAEIVCTGFDRLRLIRRI
*: :*:******:**********:**:**** **::: ***:*::*:.**
Mvan_2753|M.vanbaalenii_PYR-1 LERLPSK-PPLLELDVQDEKHLDTLADRITEVIGDGNKLDGVVHSIGFMP
Mflv_3657|M.gilvum_PYR-GCK ADRLPEK-APLLELDVQNSEHLDSLADRVSEVIGEGNKLDGVVHSIGFMP
MSMEG_3151|M.smegmatis_MC2_155 ADRLPKP-APLLELDVQNEEHLSTLADRITAEIGEGNKIDGVVHSIGFMP
MAB_2722c|M.abscessus_ATCC_199 TQRLPKP-APLLELDVQNEEHLGSLAGRISEVIGEGNKLDGVVHSIGFMP
Mb1520|M.bovis_AF2122/97 TDRLPAK-APLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMP
Rv1484|M.tuberculosis_H37Rv TDRLPAK-APLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMP
MMAR_2290|M.marinum_M VDRLPQK-APLIELDVQNEEHLASLAGRVTEVIGEGNNLDGVVHSIGFMP
MUL_1492|M.ulcerans_Agy99 VDRLPQK-APLIELDVQNEEHLASLAGRVTEVIGEGNNLDGVVHSIGFMP
MLBr_01806|M.leprae_Br4923 ADRLPDK-APLIELDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMP
MAV_3294|M.avium_104 VDRLPEK-APLIELDVQNEEHLNTLAQRVTAEIGEGNKLDGVVHSIGFMP
TH_1379|M.thermoresistible__bu VDRLPKPGAPLLELDVQNQEHLDTLADRITAEIGEGNKLDGVVHSIGFMP
:*** .**:*****:.:** :** *:: ** **::***********
Mvan_2753|M.vanbaalenii_PYR-1 QTGMGINPFFDAPYEDVAKGIHISAYSYASLAKAVLPIMNPGGGIVGMDF
Mflv_3657|M.gilvum_PYR-GCK QTGMGINPFFDAPYEDVAKGIHISAYSYASLAKAVLPIMNPGGGIVGMDF
MSMEG_3151|M.smegmatis_MC2_155 QSGMGINPFFDAPYEDVSKGIHISAYSYASLAKAVLPIMNPGGGIVGMDF
MAB_2722c|M.abscessus_ATCC_199 QSGMGVNPFFDAPFADVSKGFHISAFSYSSLAKAVLPVMNRGGSIVGMDF
Mb1520|M.bovis_AF2122/97 QTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDF
Rv1484|M.tuberculosis_H37Rv QTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDF
MMAR_2290|M.marinum_M QSGMGINPFFDAPYEDVSKGIHISAYSYASLAKALLPIMNPGGSIVGMDF
MUL_1492|M.ulcerans_Agy99 QSGMGINPFFDAPYEDVSKGIHISAYSYASLAKALLPIMNPGGSIVGMDF
MLBr_01806|M.leprae_Br4923 QTGMGTNQFFDAPYEDVSKGIHISTYSYASLAKALLLIMNSGGSIVGMDF
MAV_3294|M.avium_104 QTGMGINPFFDAPYEDVSKGIHISAYSYASLAKALLPIMNPGGSIVGMDF
TH_1379|M.thermoresistible__bu QSGMGLNPFLDTPYEDVSKGIHISAYSYAALAKATLPIMNRGGSIVGMDF
*:*** * *:*:*: **:**:***::**:::*** * :** **.******
Mvan_2753|M.vanbaalenii_PYR-1 DPTRAMPAYNWMTVAKSALESVNRFVAREAGKVGVRSNLVAAGPIRTLAM
Mflv_3657|M.gilvum_PYR-GCK DPTRAMPAYNWMTVAKSALESVNRFVAREAGKVGVRSNLVAAGPIRTLAM
MSMEG_3151|M.smegmatis_MC2_155 DPTRAMPAYNWMTVAKSALESVNRFVAREAGKVGVRSNLVAAGPIRTLAM
MAB_2722c|M.abscessus_ATCC_199 DPTRAMPAYNWMTVAKSALESVNRFVAREAGKVGVRSNLVAAGPIRTLAM
Mb1520|M.bovis_AF2122/97 DPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
Rv1484|M.tuberculosis_H37Rv DPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
MMAR_2290|M.marinum_M DPTRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
MUL_1492|M.ulcerans_Agy99 DPTRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
MLBr_01806|M.leprae_Br4923 DPTRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
MAV_3294|M.avium_104 DPSRAMPAYNWMTVAKSALESVNRFVAREAGPHGVRSNLVAAGPIRTLAM
TH_1379|M.thermoresistible__bu DPTRAMPAYNWMTVAKSALESINRFVAREAGQYGVRSNLVAAGPIRTLAM
**:******************:********* *****************
Mvan_2753|M.vanbaalenii_PYR-1 SAIVGGALGEEAGAQMQLLAEGWDQRAPLGWNMKDPTPVAKTVCALLSDW
Mflv_3657|M.gilvum_PYR-GCK SAIVGGALGDEAGAQMQLLEEGWDQRAPLGWNMKDPTPVAKTVCALLSDW
MSMEG_3151|M.smegmatis_MC2_155 SAIVGGALGDEAGQQMQLLEEGWDQRAPLGWNMKDPTPVAKTVCALLSDW
MAB_2722c|M.abscessus_ATCC_199 SAIVGGALGDEAGQQMQLLEEGWDQRAPIGWDMKDPTPVAKTVCALLSDW
Mb1520|M.bovis_AF2122/97 SAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDW
Rv1484|M.tuberculosis_H37Rv SAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDW
MMAR_2290|M.marinum_M SAIVGGALGEEAGAQIQLLEDGWDQRAPVGWNMKDPTPVAKTVCAVLSEW
MUL_1492|M.ulcerans_Agy99 SAIVGGALGEEAGAQIQLLEDGWDQRAPVGWNMKDPTPVAKTVCAVLSEW
MLBr_01806|M.leprae_Br4923 SAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWNMKDPTPVAKTVCALLSEW
MAV_3294|M.avium_104 AGIVGGVLGDQAAEQIRLLEEGWDQRAPIGWNMKDPTPVAKTVCALLSDW
TH_1379|M.thermoresistible__bu SAIVGGALGEEAGEQMKLLEEGWDQRAPLGWDMKDPTPVAKTVLALISDW
:.****.:*::*. *::** :*******:**:***.******* *::*:*
Mvan_2753|M.vanbaalenii_PYR-1 LPATTGTVIFADGGASTQLL
Mflv_3657|M.gilvum_PYR-GCK LPATTGTVIFADGGASTQLL
MSMEG_3151|M.smegmatis_MC2_155 LPATTGTVIYADGGASTQLL
MAB_2722c|M.abscessus_ATCC_199 LPATTGDIIFADGGAHTQLL
Mb1520|M.bovis_AF2122/97 LPATTGDIIYADGGAHTQLL
Rv1484|M.tuberculosis_H37Rv LPATTGDIIYADGGAHTQLL
MMAR_2290|M.marinum_M LPATTGDIIFADGGAHTQLL
MUL_1492|M.ulcerans_Agy99 LPATTGDIIFADGGAHTQLL
MLBr_01806|M.leprae_Br4923 LPATTGSIIYADGGASTQLL
MAV_3294|M.avium_104 LPATTGTIIYADGGASTQLL
TH_1379|M.thermoresistible__bu MPATTGTVIYADGGASQQLL
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