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M. ulcerans Agy99 MUL_1492 (inhA)

annotation: enoyl-(acyl carrier protein) reductase
coordinates: 1615505 - 1616314
length: 269

MAGLLEGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRMRLIQRIVDRLPQKAPLIELDVQNEEH
LASLAGRVTEVIGEGNNLDGVVHSIGFMPQSGMGINPFFDAPYEDVSKGIHISAYSYASLAKALLPIMNP
GGSIVGMDFDPTRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEE
AGAQIQLLEDGWDQRAPVGWNMKDPTPVAKTVCAVLSEWLPATTGDIIFADGGAHTQLL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1492inhA-100% (269)enoyl-(acyl carrier protein) reductase
M. ulcerans Agy99MUL_4844-9e-0823.68% (266) short-chain type dehydrogenase/reductase
M. ulcerans Agy99MUL_0327-5e-0624.26% (136) oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1520inhA1e-14492.94% (269) enoyl-(acyl carrier protein) reductase
M. gilvum PYR-GCKMflv_3657-1e-13789.47% (266) enoyl-(acyl carrier protein) reductase
M. tuberculosis H37RvRv1484inhA1e-14492.94% (269) enoyl-(acyl carrier protein) reductase
M. leprae Br4923MLBr_01806inhA1e-13991.08% (269) enoyl-(acyl carrier protein) reductase
M. abscessus ATCC 19977MAB_2722c-1e-13887.73% (269) enoyl-(acyl carrier protein) reductase
M. marinum MMMAR_2290inhA1e-152100.00% (269) enoyl-
M. avium 104MAV_3294-1e-13788.48% (269) enoyl-(acyl carrier protein) reductase
M. smegmatis MC2 155MSMEG_3151-1e-13686.99% (269) enoyl-(acyl carrier protein) reductase
M. thermoresistible (build 8)TH_1379inhA1e-13083.70% (270) NADH-DEPENDENT ENOYL-
M. vanbaalenii PYR-1Mvan_2753-1e-13485.13% (269) enoyl-(acyl carrier protein) reductase

CLUSTAL 2.0.9 multiple sequence alignment


MUL_1492|M.ulcerans_Agy99           MAGLLEGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRMRLIQRI
MMAR_2290|M.marinum_M               MAGLLEGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRMRLIQRI
Mb1520|M.bovis_AF2122/97            MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRI
Rv1484|M.tuberculosis_H37Rv         MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRI
MLBr_01806|M.leprae_Br4923          MAGLLEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRI
MAV_3294|M.avium_104                MAGLLDGKRILVTGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRI
Mflv_3657|M.gilvum_PYR-GCK          MT-LLQGKRILVTGIITDSSIAFHIAKVAQEAGAELVLTGFDRMKLIQRI
Mvan_2753|M.vanbaalenii_PYR-1       MTGILEGKRILVTGIITDSSIAFYIAKVAQEAGAEVICTGFNRLRLIERI
MSMEG_3151|M.smegmatis_MC2_155      MTGLLEGKRILVTGIITDSSIAFHIAKVAQEAGAELVLTGFDRLKLVKRI
MAB_2722c|M.abscessus_ATCC_199      MAGLLEGKRILVTGIITDSSIAFHIAKVAQEQGAELVLTGFDRLRLIERI
TH_1379|M.thermoresistible__bu      MAGFLEGKRILVTGIITDSSIAFHIARVAQEAGAEIVCTGFDRLRLIRRI
                                    *: :*:******:**********:**:**** **::: ***:*::*:.**

MUL_1492|M.ulcerans_Agy99           VDRLPQK-APLIELDVQNEEHLASLAGRVTEVIGEGNNLDGVVHSIGFMP
MMAR_2290|M.marinum_M               VDRLPQK-APLIELDVQNEEHLASLAGRVTEVIGEGNNLDGVVHSIGFMP
Mb1520|M.bovis_AF2122/97            TDRLPAK-APLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMP
Rv1484|M.tuberculosis_H37Rv         TDRLPAK-APLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMP
MLBr_01806|M.leprae_Br4923          ADRLPDK-APLIELDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMP
MAV_3294|M.avium_104                VDRLPEK-APLIELDVQNEEHLNTLAQRVTAEIGEGNKLDGVVHSIGFMP
Mflv_3657|M.gilvum_PYR-GCK          ADRLPEK-APLLELDVQNSEHLDSLADRVSEVIGEGNKLDGVVHSIGFMP
Mvan_2753|M.vanbaalenii_PYR-1       LERLPSK-PPLLELDVQDEKHLDTLADRITEVIGDGNKLDGVVHSIGFMP
MSMEG_3151|M.smegmatis_MC2_155      ADRLPKP-APLLELDVQNEEHLSTLADRITAEIGEGNKIDGVVHSIGFMP
MAB_2722c|M.abscessus_ATCC_199      TQRLPKP-APLLELDVQNEEHLGSLAGRISEVIGEGNKLDGVVHSIGFMP
TH_1379|M.thermoresistible__bu      VDRLPKPGAPLLELDVQNQEHLDTLADRITAEIGEGNKLDGVVHSIGFMP
                                     :***   .**:*****:.:** :** *::  ** **::***********

MUL_1492|M.ulcerans_Agy99           QSGMGINPFFDAPYEDVSKGIHISAYSYASLAKALLPIMNPGGSIVGMDF
MMAR_2290|M.marinum_M               QSGMGINPFFDAPYEDVSKGIHISAYSYASLAKALLPIMNPGGSIVGMDF
Mb1520|M.bovis_AF2122/97            QTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDF
Rv1484|M.tuberculosis_H37Rv         QTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDF
MLBr_01806|M.leprae_Br4923          QTGMGTNQFFDAPYEDVSKGIHISTYSYASLAKALLLIMNSGGSIVGMDF
MAV_3294|M.avium_104                QTGMGINPFFDAPYEDVSKGIHISAYSYASLAKALLPIMNPGGSIVGMDF
Mflv_3657|M.gilvum_PYR-GCK          QTGMGINPFFDAPYEDVAKGIHISAYSYASLAKAVLPIMNPGGGIVGMDF
Mvan_2753|M.vanbaalenii_PYR-1       QTGMGINPFFDAPYEDVAKGIHISAYSYASLAKAVLPIMNPGGGIVGMDF
MSMEG_3151|M.smegmatis_MC2_155      QSGMGINPFFDAPYEDVSKGIHISAYSYASLAKAVLPIMNPGGGIVGMDF
MAB_2722c|M.abscessus_ATCC_199      QSGMGVNPFFDAPFADVSKGFHISAFSYSSLAKAVLPVMNRGGSIVGMDF
TH_1379|M.thermoresistible__bu      QSGMGLNPFLDTPYEDVSKGIHISAYSYAALAKATLPIMNRGGSIVGMDF
                                    *:*** * *:*:*: **:**:***::**:::*** * :** **.******

MUL_1492|M.ulcerans_Agy99           DPTRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
MMAR_2290|M.marinum_M               DPTRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
Mb1520|M.bovis_AF2122/97            DPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
Rv1484|M.tuberculosis_H37Rv         DPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
MLBr_01806|M.leprae_Br4923          DPTRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
MAV_3294|M.avium_104                DPSRAMPAYNWMTVAKSALESVNRFVAREAGPHGVRSNLVAAGPIRTLAM
Mflv_3657|M.gilvum_PYR-GCK          DPTRAMPAYNWMTVAKSALESVNRFVAREAGKVGVRSNLVAAGPIRTLAM
Mvan_2753|M.vanbaalenii_PYR-1       DPTRAMPAYNWMTVAKSALESVNRFVAREAGKVGVRSNLVAAGPIRTLAM
MSMEG_3151|M.smegmatis_MC2_155      DPTRAMPAYNWMTVAKSALESVNRFVAREAGKVGVRSNLVAAGPIRTLAM
MAB_2722c|M.abscessus_ATCC_199      DPTRAMPAYNWMTVAKSALESVNRFVAREAGKVGVRSNLVAAGPIRTLAM
TH_1379|M.thermoresistible__bu      DPTRAMPAYNWMTVAKSALESINRFVAREAGQYGVRSNLVAAGPIRTLAM
                                    **:******************:*********  *****************

MUL_1492|M.ulcerans_Agy99           SAIVGGALGEEAGAQIQLLEDGWDQRAPVGWNMKDPTPVAKTVCAVLSEW
MMAR_2290|M.marinum_M               SAIVGGALGEEAGAQIQLLEDGWDQRAPVGWNMKDPTPVAKTVCAVLSEW
Mb1520|M.bovis_AF2122/97            SAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDW
Rv1484|M.tuberculosis_H37Rv         SAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDW
MLBr_01806|M.leprae_Br4923          SAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWNMKDPTPVAKTVCALLSEW
MAV_3294|M.avium_104                AGIVGGVLGDQAAEQIRLLEEGWDQRAPIGWNMKDPTPVAKTVCALLSDW
Mflv_3657|M.gilvum_PYR-GCK          SAIVGGALGDEAGAQMQLLEEGWDQRAPLGWNMKDPTPVAKTVCALLSDW
Mvan_2753|M.vanbaalenii_PYR-1       SAIVGGALGEEAGAQMQLLAEGWDQRAPLGWNMKDPTPVAKTVCALLSDW
MSMEG_3151|M.smegmatis_MC2_155      SAIVGGALGDEAGQQMQLLEEGWDQRAPLGWNMKDPTPVAKTVCALLSDW
MAB_2722c|M.abscessus_ATCC_199      SAIVGGALGDEAGQQMQLLEEGWDQRAPIGWDMKDPTPVAKTVCALLSDW
TH_1379|M.thermoresistible__bu      SAIVGGALGEEAGEQMKLLEEGWDQRAPLGWDMKDPTPVAKTVLALISDW
                                    :.****.:*::*. *::** :*******:**:***.******* *::*:*

MUL_1492|M.ulcerans_Agy99           LPATTGDIIFADGGAHTQLL
MMAR_2290|M.marinum_M               LPATTGDIIFADGGAHTQLL
Mb1520|M.bovis_AF2122/97            LPATTGDIIYADGGAHTQLL
Rv1484|M.tuberculosis_H37Rv         LPATTGDIIYADGGAHTQLL
MLBr_01806|M.leprae_Br4923          LPATTGSIIYADGGASTQLL
MAV_3294|M.avium_104                LPATTGTIIYADGGASTQLL
Mflv_3657|M.gilvum_PYR-GCK          LPATTGTVIFADGGASTQLL
Mvan_2753|M.vanbaalenii_PYR-1       LPATTGTVIFADGGASTQLL
MSMEG_3151|M.smegmatis_MC2_155      LPATTGTVIYADGGASTQLL
MAB_2722c|M.abscessus_ATCC_199      LPATTGDIIFADGGAHTQLL
TH_1379|M.thermoresistible__bu      MPATTGTVIYADGGASQQLL
                                    :***** :*:*****  ***