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M. thermoresistible (build 8) TH_1379 (inhA)

annotation: NADH-DEPENDENT ENOYL-
coordinates: 2610922 - 2611734
length: 271

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1379inhA-100% (271)NADH-DEPENDENT ENOYL-
M. thermoresistible (build 8)TH_2488-1e-0925.91% (274) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3237-3e-0928.03% (289) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1520inhA1e-12882.96% (270) enoyl-(acyl carrier protein) reductase
M. gilvum PYR-GCKMflv_3657-1e-13185.71% (266) enoyl-(acyl carrier protein) reductase
M. tuberculosis H37RvRv1484inhA1e-12882.96% (270) enoyl-(acyl carrier protein) reductase
M. leprae Br4923MLBr_01806inhA1e-13285.19% (270) enoyl-(acyl carrier protein) reductase
M. abscessus ATCC 19977MAB_2722c-1e-13084.07% (270) enoyl-(acyl carrier protein) reductase
M. marinum MMMAR_2290inhA1e-13083.70% (270) enoyl-
M. avium 104MAV_3294-1e-13384.81% (270) enoyl-(acyl carrier protein) reductase
M. smegmatis MC2 155MSMEG_3151-1e-13788.52% (270) enoyl-(acyl carrier protein) reductase
M. ulcerans Agy99MUL_1492inhA1e-13083.70% (270) enoyl-(acyl carrier protein) reductase
M. vanbaalenii PYR-1Mvan_2753-1e-13185.24% (271) enoyl-(acyl carrier protein) reductase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3657|M.gilvum_PYR-GCK          MT-LLQGKRILVTGIITDSSIAFHIAKVAQEAGAELVLTGFDRMKLIQRI
Mvan_2753|M.vanbaalenii_PYR-1       MTGILEGKRILVTGIITDSSIAFYIAKVAQEAGAEVICTGFNRLRLIERI
MSMEG_3151|M.smegmatis_MC2_155      MTGLLEGKRILVTGIITDSSIAFHIAKVAQEAGAELVLTGFDRLKLVKRI
MAB_2722c|M.abscessus_ATCC_199      MAGLLEGKRILVTGIITDSSIAFHIAKVAQEQGAELVLTGFDRLRLIERI
Mb1520|M.bovis_AF2122/97            MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRI
Rv1484|M.tuberculosis_H37Rv         MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRI
MMAR_2290|M.marinum_M               MAGLLEGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRMRLIQRI
MUL_1492|M.ulcerans_Agy99           MAGLLEGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRMRLIQRI
MLBr_01806|M.leprae_Br4923          MAGLLEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRI
MAV_3294|M.avium_104                MAGLLDGKRILVTGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLIQRI
TH_1379|M.thermoresistible__bu      MAGFLEGKRILVTGIITDSSIAFHIARVAQEAGAEIVCTGFDRLRLIRRI
                                    *: :*:******:**********:**:**** **::: ***:*::*:.**

Mflv_3657|M.gilvum_PYR-GCK          ADRLPEK-APLLELDVQNSEHLDSLADRVSEVIGEGNKLDGVVHSIGFMP
Mvan_2753|M.vanbaalenii_PYR-1       LERLPSK-PPLLELDVQDEKHLDTLADRITEVIGDGNKLDGVVHSIGFMP
MSMEG_3151|M.smegmatis_MC2_155      ADRLPKP-APLLELDVQNEEHLSTLADRITAEIGEGNKIDGVVHSIGFMP
MAB_2722c|M.abscessus_ATCC_199      TQRLPKP-APLLELDVQNEEHLGSLAGRISEVIGEGNKLDGVVHSIGFMP
Mb1520|M.bovis_AF2122/97            TDRLPAK-APLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMP
Rv1484|M.tuberculosis_H37Rv         TDRLPAK-APLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMP
MMAR_2290|M.marinum_M               VDRLPQK-APLIELDVQNEEHLASLAGRVTEVIGEGNNLDGVVHSIGFMP
MUL_1492|M.ulcerans_Agy99           VDRLPQK-APLIELDVQNEEHLASLAGRVTEVIGEGNNLDGVVHSIGFMP
MLBr_01806|M.leprae_Br4923          ADRLPDK-APLIELDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMP
MAV_3294|M.avium_104                VDRLPEK-APLIELDVQNEEHLNTLAQRVTAEIGEGNKLDGVVHSIGFMP
TH_1379|M.thermoresistible__bu      VDRLPKPGAPLLELDVQNQEHLDTLADRITAEIGEGNKLDGVVHSIGFMP
                                     :***   .**:*****:.:** :** *::  ** **::***********

Mflv_3657|M.gilvum_PYR-GCK          QTGMGINPFFDAPYEDVAKGIHISAYSYASLAKAVLPIMNPGGGIVGMDF
Mvan_2753|M.vanbaalenii_PYR-1       QTGMGINPFFDAPYEDVAKGIHISAYSYASLAKAVLPIMNPGGGIVGMDF
MSMEG_3151|M.smegmatis_MC2_155      QSGMGINPFFDAPYEDVSKGIHISAYSYASLAKAVLPIMNPGGGIVGMDF
MAB_2722c|M.abscessus_ATCC_199      QSGMGVNPFFDAPFADVSKGFHISAFSYSSLAKAVLPVMNRGGSIVGMDF
Mb1520|M.bovis_AF2122/97            QTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDF
Rv1484|M.tuberculosis_H37Rv         QTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDF
MMAR_2290|M.marinum_M               QSGMGINPFFDAPYEDVSKGIHISAYSYASLAKALLPIMNPGGSIVGMDF
MUL_1492|M.ulcerans_Agy99           QSGMGINPFFDAPYEDVSKGIHISAYSYASLAKALLPIMNPGGSIVGMDF
MLBr_01806|M.leprae_Br4923          QTGMGTNQFFDAPYEDVSKGIHISTYSYASLAKALLLIMNSGGSIVGMDF
MAV_3294|M.avium_104                QTGMGINPFFDAPYEDVSKGIHISAYSYASLAKALLPIMNPGGSIVGMDF
TH_1379|M.thermoresistible__bu      QSGMGLNPFLDTPYEDVSKGIHISAYSYAALAKATLPIMNRGGSIVGMDF
                                    *:*** * *:*:*: **:**:***::**:::*** * :** **.******

Mflv_3657|M.gilvum_PYR-GCK          DPTRAMPAYNWMTVAKSALESVNRFVAREAGKVGVRSNLVAAGPIRTLAM
Mvan_2753|M.vanbaalenii_PYR-1       DPTRAMPAYNWMTVAKSALESVNRFVAREAGKVGVRSNLVAAGPIRTLAM
MSMEG_3151|M.smegmatis_MC2_155      DPTRAMPAYNWMTVAKSALESVNRFVAREAGKVGVRSNLVAAGPIRTLAM
MAB_2722c|M.abscessus_ATCC_199      DPTRAMPAYNWMTVAKSALESVNRFVAREAGKVGVRSNLVAAGPIRTLAM
Mb1520|M.bovis_AF2122/97            DPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
Rv1484|M.tuberculosis_H37Rv         DPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
MMAR_2290|M.marinum_M               DPTRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
MUL_1492|M.ulcerans_Agy99           DPTRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
MLBr_01806|M.leprae_Br4923          DPTRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAM
MAV_3294|M.avium_104                DPSRAMPAYNWMTVAKSALESVNRFVAREAGPHGVRSNLVAAGPIRTLAM
TH_1379|M.thermoresistible__bu      DPTRAMPAYNWMTVAKSALESINRFVAREAGQYGVRSNLVAAGPIRTLAM
                                    **:******************:*********  *****************

Mflv_3657|M.gilvum_PYR-GCK          SAIVGGALGDEAGAQMQLLEEGWDQRAPLGWNMKDPTPVAKTVCALLSDW
Mvan_2753|M.vanbaalenii_PYR-1       SAIVGGALGEEAGAQMQLLAEGWDQRAPLGWNMKDPTPVAKTVCALLSDW
MSMEG_3151|M.smegmatis_MC2_155      SAIVGGALGDEAGQQMQLLEEGWDQRAPLGWNMKDPTPVAKTVCALLSDW
MAB_2722c|M.abscessus_ATCC_199      SAIVGGALGDEAGQQMQLLEEGWDQRAPIGWDMKDPTPVAKTVCALLSDW
Mb1520|M.bovis_AF2122/97            SAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDW
Rv1484|M.tuberculosis_H37Rv         SAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDW
MMAR_2290|M.marinum_M               SAIVGGALGEEAGAQIQLLEDGWDQRAPVGWNMKDPTPVAKTVCAVLSEW
MUL_1492|M.ulcerans_Agy99           SAIVGGALGEEAGAQIQLLEDGWDQRAPVGWNMKDPTPVAKTVCAVLSEW
MLBr_01806|M.leprae_Br4923          SAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWNMKDPTPVAKTVCALLSEW
MAV_3294|M.avium_104                AGIVGGVLGDQAAEQIRLLEEGWDQRAPIGWNMKDPTPVAKTVCALLSDW
TH_1379|M.thermoresistible__bu      SAIVGGALGEEAGEQMKLLEEGWDQRAPLGWDMKDPTPVAKTVLALISDW
                                    :.****.:*::*. *::** :*******:**:***.******* *::*:*

Mflv_3657|M.gilvum_PYR-GCK          LPATTGTVIFADGGASTQLL
Mvan_2753|M.vanbaalenii_PYR-1       LPATTGTVIFADGGASTQLL
MSMEG_3151|M.smegmatis_MC2_155      LPATTGTVIYADGGASTQLL
MAB_2722c|M.abscessus_ATCC_199      LPATTGDIIFADGGAHTQLL
Mb1520|M.bovis_AF2122/97            LPATTGDIIYADGGAHTQLL
Rv1484|M.tuberculosis_H37Rv         LPATTGDIIYADGGAHTQLL
MMAR_2290|M.marinum_M               LPATTGDIIFADGGAHTQLL
MUL_1492|M.ulcerans_Agy99           LPATTGDIIFADGGAHTQLL
MLBr_01806|M.leprae_Br4923          LPATTGSIIYADGGASTQLL
MAV_3294|M.avium_104                LPATTGTIIYADGGASTQLL
TH_1379|M.thermoresistible__bu      MPATTGTVIYADGGASQQLL
                                    :***** :*:*****  ***