For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MCVLALCGCAVPETVGRAQPAGPRVVFSDEFDGPAGGRPSAQWRFDTGGGGWGNNEWQVYTSDPANVSLD GAGHLAIVARGDADGSNITSARATTKAAVELTNGRAEARIALPAGVGLHAAFWLLGSDVDRVGWPAAGEI DVIETLNLADEYHTGVHAPRAGSPRGQEVSAAGPVPFPLAGEFRTYWVDKTPGRIVTGVDDVTLFSVTPA DLAPESTWVFDAPFFLLLNLAVGGNWPGPPDATTPNPSRMLVDWVRATER
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2679 | - | - | 100% (260) | glycoside hydrolase family protein |
| M. vanbaalenii PYR-1 | Mvan_2739 | - | 2e-22 | 34.50% (258) | glycoside hydrolase family protein |
| M. vanbaalenii PYR-1 | Mvan_0446 | - | 2e-12 | 29.67% (273) | glycoside hydrolase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0323 | - | 5e-11 | 30.15% (272) | beta-1,3-glucanase precursor |
| M. gilvum PYR-GCK | Mflv_0298 | - | 2e-14 | 31.64% (275) | glycoside hydrolase family protein |
| M. tuberculosis H37Rv | Rv0315 | - | 5e-11 | 30.15% (272) | beta-1,3-glucanase precursor |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4740 | - | 2e-14 | 32.81% (253) | beta-1,3-glucanase |
| M. marinum M | MMAR_0567 | - | 6e-14 | 31.11% (270) | beta-1,3-glucanase precursor |
| M. avium 104 | MAV_2761 | - | 9e-10 | 28.36% (275) | glycosyl hydrolases family protein 16 |
| M. smegmatis MC2 155 | MSMEG_0645 | - | 2e-13 | 30.66% (274) | putative beta-1,3-glucanase |
| M. thermoresistible (build 8) | TH_0196 | - | 8e-12 | 31.20% (266) | POSSIBLE BETA-1,3-GLUCANASE PRECURSOR |
| M. ulcerans Agy99 | MUL_4744 | - | 8e-14 | 30.74% (270) | beta-1,3-glucanase precursor |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4740|M.abscessus_ATCC_1997 -----MDRRRMMAFSGLGMLAAAASMPQAWAQP----SPLGPPNRP--PA
MAV_2761|M.avium_104 --MPEIDRRRMIVTTGIGVLAAALPNPRAGASP----AP--PPAAP--SG
Mflv_0298|M.gilvum_PYR-GCK --MPEMDRRKAMLMMGLGAAVVASPLGSAHAQP----PA--VPSEP-LPA
MSMEG_0645|M.smegmatis_MC2_155 ----------MMFMMGLGVAAAALPVGTAGADP----LIGDNPPGP-GPA
TH_0196|M.thermoresistible__bu --MPMMNRRQAMMMLGFGAVAAALPLPQAGAQP----VLDAPAPGPDTPE
Mb0323|M.bovis_AF2122/97 MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAPA
Rv0315|M.tuberculosis_H37Rv MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAPA
MMAR_0567|M.marinum_M MLMQEIDRRRMIMMAGFGALAAAIPAPTAGAAP---TPPAAPEPAPAAPA
MUL_4744|M.ulcerans_Agy99 MLMQEIDRRRIIMMAGFGALAAAIPAPTAGAAP---IPPAAPEPAPAAPA
Mvan_2679|M.vanbaalenii_PYR-1 -------------MCVLALCGCAVPETVGRAQP-----------------
:. * . . * *
MAB_4740|M.abscessus_ATCC_1997 APPTGKYVFVDEFDGPAGSAPDGSKWAISKARETMKDPTFWELPENVGQY
MAV_2761|M.avium_104 Q--SGTYLFQDEFDGPAGSAPDASKWAVAKARETIKDPTYWERPENIGQY
Mflv_0298|M.gilvum_PYR-GCK GDAGPLMLFQDEFDGPAGAPPDPARWFIVPARETIRNPVEWDKPFNMGRY
MSMEG_0645|M.smegmatis_MC2_155 AAAEPTFLFQDEFNGPAGSPPDPAWWYLVPARETIKNPVEWDKPYNMGRY
TH_0196|M.thermoresistible__bu AASGPGLLFADEFDGPAGSPPDPAKWFIVPERETIRNPVEWDKPYNMGRY
Mb0323|M.bovis_AF2122/97 AATG-GLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQY
Rv0315|M.tuberculosis_H37Rv AATG-GLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQY
MMAR_0567|M.marinum_M AGAGPIFLWHDEFDGPAGSAPDPAKWQVSNHRTPIRNPVGFDRPEFWGQY
MUL_4744|M.ulcerans_Agy99 AGAGPIFLWHDEFDGPAGSAPDPSKWQVSNHRTPIRNPVGFDRPEFWGQY
Mvan_2679|M.vanbaalenii_PYR-1 --AGPRVVFSDEFDGPAGGRP-SAQWRFDTGGGGWGN-------NEWQVY
:: ***:****. * : * . : *
MAB_4740|M.abscessus_ATCC_1997 RDDRKNVFLDGNSNLVIKAAK-EGN----TYYGGKIYSTTELGIGYTWEA
MAV_2761|M.avium_104 RDDRRNVFLDGKSNLVLRAAK-DGP----TYYSGKVQSLWRGGVGHTWEA
Mflv_0298|M.gilvum_PYR-GCK VTDQEHVFQDGNGNLVIRATRGEGTTIQEKYASAKIMGTWRGGIGTTWEA
MSMEG_0645|M.smegmatis_MC2_155 VTDQEHAFQDGKGNLVIRATRGPGTTIQEKYASAKVVGLWRGGIGTTWEA
TH_0196|M.thermoresistible__bu VTDQEHVFHDGNGNLVIRATRGPGANIREKYASAKIVGLWRGGVGTTWEA
Mb0323|M.bovis_AF2122/97 RDSRQNVFLDGNSNLVLRATR-EGN----RYFGGLVHGLWRGGIGTTWEA
Rv0315|M.tuberculosis_H37Rv RDSRQNVFLDGNSNLVLRATR-EGN----RYFGGLVHGLWRGGIGTTWEA
MMAR_0567|M.marinum_M RDNRQNVFLDGNSNLVLRATR-SGN----DYFGGLVHGLWRGGIGTTWEA
MUL_4744|M.ulcerans_Agy99 RDNRQNVFLDGNSNLVLRATR-SGN----DYFGGLVHGLWRGGIGTTWEA
Mvan_2679|M.vanbaalenii_PYR-1 TSDPANVSLDGAGHLAIVARG-DADGSNITSARATTKAAVELTNG-RAEA
. :. ** .:*.: * . . . . * **
MAB_4740|M.abscessus_ATCC_1997 RIKFNCLTPGAWPAFWLGSDQ--------DGEIDIVEWYGNGSWPSATTV
MAV_2761|M.avium_104 RIKLDCLTAGAWPAYWLGNDD--------QGEIDVMEWYGNGNWPSATTV
Mflv_0298|M.gilvum_PYR-GCK RVKLDCLTDGAWPAFWLVNENPV-----RGGEVDLVEWYGNNDWPSGTTV
MSMEG_0645|M.smegmatis_MC2_155 RVKLNCLTDGAWPAFWLLNDNPV-----RGGEVDLVEWYGNRDWPSGTTV
TH_0196|M.thermoresistible__bu RVKLNCLTDGAWPAFWLLNDDPV-----RGAEIDIFEWYGNRDWPSGATV
Mb0323|M.bovis_AF2122/97 RIKFNCLAPGMWPAWWLSNDDPG-----RSGEIDLIEWYGNGTWPSGTTV
Rv0315|M.tuberculosis_H37Rv RIKFNCLAPGMWPAWWLSNDDPG-----RSGEIDLIEWYGNGTWPSGTTV
MMAR_0567|M.marinum_M RIKFNCLAPGMWPAWWLSNDDPG-----RSGEIDLIEWYGNGSWPSGTTV
MUL_4744|M.ulcerans_Agy99 RIKFNCLAPGMWPAWWLSNDDPG-----RSGEIDLIEWYGNGSWPSGTTV
Mvan_2679|M.vanbaalenii_PYR-1 RIALPAG-VGLHAAFWLLGSDVDRVGWPAAGEIDVIETLN-LADEYHTGV
*: : . * .*:** ..: .*:*:.* . : *
MAB_4740|M.abscessus_ATCC_1997 HAKANGSEWKTHNISLDSG----WHTWRTQWDDKGIRFWKDYTDGATPYF
MAV_2761|M.avium_104 HAKANGGEWKTHNIAVDSA----WHTWRCQWDEAGIRFWKDYVDGAQPYF
Mflv_0298|M.gilvum_PYR-GCK HARLDGTAFATNRHPVDNA----WHTWRMTWQPTGLYFWKDYQPGMEPFF
MSMEG_0645|M.smegmatis_MC2_155 HARLDGTSFATNPHPVDSD----WHTWRMSWKPEGMYFWKDYAPGMEPFF
TH_0196|M.thermoresistible__bu HAKLDGTMFQTQNYPVDSA----WHTWRMTWLPSGMYFWQDYEPGKEPFF
Mb0323|M.bovis_AF2122/97 HANPDGTAFETCPIGVDGG----WHNWRVTWNPSGMYFWLDYADGIEPYF
Rv0315|M.tuberculosis_H37Rv HANPDGTAFETCPIGVDGG----WHNWRVTWNPSGMYFWLDYADGIEPYF
MMAR_0567|M.marinum_M HANPDGTAFETFPIGVDDN----WHNWRVTWNVTGMYFWLDYADGMQPYF
MUL_4744|M.ulcerans_Agy99 HANPDGTAFETFPIGVDDN----WYNWRVTWNVTGMYFWLDYADGMQPYF
Mvan_2679|M.vanbaalenii_PYR-1 HAPRAGSPRGQEVSAAGPVPFPLAGEFRTYWVDKTPGRIVTGVDDVTLFS
** * . :* * . :
MAB_4740|M.abscessus_ATCC_1997 EVPAN-------SLADWPFNNPGHKAFAVLNLAVAGSGGGDPRGGT-YPA
MAV_2761|M.avium_104 DVPAS-------SLPDWPFNGPGYTVFPVFNLAVAGSGGGDPGPGS-YPA
Mflv_0298|M.gilvum_PYR-GCK TVPAN-------SIPDWPFNDPGFTMVPVFNIAVGGSGGREPAAGT-YPA
MSMEG_0645|M.smegmatis_MC2_155 SVPAN-------SLQDWPFNDPGYTMVPVFNIAVGGSGGREPAGGT-YPA
TH_0196|M.thermoresistible__bu TVLAN-------SLPEWPFNDPGYTMVPVFNIAVGGSGGREPAGGS-YPA
Mb0323|M.bovis_AF2122/97 SVPATGIEDLNEPIREWPFNDPGYTVFPVLNLAVGGSGGGDPATGS-YPQ
Rv0315|M.tuberculosis_H37Rv SVPATGIEDLNEPIREWPFNDPGYKVFPVLNLAVGGSGGGDPATGS-YPQ
MMAR_0567|M.marinum_M SVPATGIEDLNEPIREWPFNDPDYTVFPVLNLAVGGSGGGDPAAGT-YPQ
MUL_4744|M.ulcerans_Agy99 SVPATGIEDLNEPIREWPFNDPDYTVFPVLNLAVGGSGGGDPAAGT-YPQ
Mvan_2679|M.vanbaalenii_PYR-1 VTPAD-----LAPESTWVFDAP---FFLLLNLAVGGNWPGPPDATTPNPS
. * . * *: * . ::*:**.*. * : *
MAB_4740|M.abscessus_ATCC_1997 EMLVDWIRVW--
MAV_2761|M.avium_104 DMLIDWIRVW--
Mflv_0298|M.gilvum_PYR-GCK EMRVDWIRVFAS
MSMEG_0645|M.smegmatis_MC2_155 EMLVDWIRVFAG
TH_0196|M.thermoresistible__bu DMIIDWIRVF--
Mb0323|M.bovis_AF2122/97 EMLVDWVRVF--
Rv0315|M.tuberculosis_H37Rv EMLVDWVRVF--
MMAR_0567|M.marinum_M EMLVDWVRVF--
MUL_4744|M.ulcerans_Agy99 EMLVDWVRVF--
Mvan_2679|M.vanbaalenii_PYR-1 RMLVDWVRATER
* :**:*.