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M. abscessus ATCC 19977 MAB_4740 (-)

annotation: beta-1,3-glucanase
coordinates: 4851521 - 4852345
length: 274

MDRRRMMAFSGLGMLAAAASMPQAWAQPSPLGPPNRPPAAPPTGKYVFVDEFDGPAGSAPDGSKWAISKA
RETMKDPTFWELPENVGQYRDDRKNVFLDGNSNLVIKAAKEGNTYYGGKIYSTTELGIGYTWEARIKFNC
LTPGAWPAFWLGSDQDGEIDIVEWYGNGSWPSATTVHAKANGSEWKTHNISLDSGWHTWRTQWDDKGIRF
WKDYTDGATPYFEVPANSLADWPFNNPGHKAFAVLNLAVAGSGGGDPRGGTYPAEMLVDWIRVW
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_4740--100% (274)beta-1,3-glucanase
M. abscessus ATCC 19977MAB_1840c-1e-9860.67% (267) putative beta-glucanase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0323-9e-9957.44% (289) beta-1,3-glucanase precursor
M. gilvum PYR-GCKMflv_0298-2e-8452.13% (282) glycoside hydrolase family protein
M. tuberculosis H37RvRv0315-2e-9957.79% (289) beta-1,3-glucanase precursor
M. leprae Br4923-----
M. marinum MMMAR_2902-1e-12170.44% (274) beta-1,3-glucanase precursor
M. avium 104MAV_2761-1e-12470.29% (276) glycosyl hydrolases family protein 16
M. smegmatis MC2 155MSMEG_5345-1e-11767.52% (274) glycosyl hydrolases family protein 16
M. thermoresistible (build 8)TH_0196-5e-8451.58% (285) POSSIBLE BETA-1,3-GLUCANASE PRECURSOR
M. ulcerans Agy99MUL_4744-1e-9455.05% (287) beta-1,3-glucanase precursor
M. vanbaalenii PYR-1Mvan_0446-2e-8654.67% (289) glycoside hydrolase family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0323|M.bovis_AF2122/97            MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAPA
Rv0315|M.tuberculosis_H37Rv         MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAPA
MUL_4744|M.ulcerans_Agy99           MLMQEIDRRRIIMMAGFGALAAAIPAPTAGAAP---IPPAAPEPAPAAPA
MMAR_2902|M.marinum_M               --MPEMDRRRMMLMTGFGVLGAALPVPAASADSSRRDMPLAPAPNGQSGP
MAV_2761|M.avium_104                --MPEIDRRRMIVTTGIGVLAAALPNPRAGASP----APPPAAPSGQSGT
MSMEG_5345|M.smegmatis_MC2_155      --MANVDRRQMLLLSGLGATAAVLPVPRA-----------AAVPNQTAAS
MAB_4740|M.abscessus_ATCC_1997      -----MDRRRMMAFSGLGMLAAAASMPQAWAQPSPLGPPNRPPAAPPTGK
TH_0196|M.thermoresistible__bu      --MPMMNRRQAMMMLGFGAVAAALPLPQAGAQPVL-DAPAPGPDTP--EA
Mvan_0446|M.vanbaalenii_PYR-1       -----MDRRRAMLTLGFGMAAAALPFPKAGAQPVIGDAPPPGPSGPGLPE
Mflv_0298|M.gilvum_PYR-GCK          --MPEMDRRKAMLMMGLGAAVVASPLGSAHAQ------PPAVPSEPLPAG
                                         ::**: :   *:*   .. .   *                     

Mb0323|M.bovis_AF2122/97            AATG-GLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQY
Rv0315|M.tuberculosis_H37Rv         AATG-GLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQY
MUL_4744|M.ulcerans_Agy99           AGAGPIFLWHDEFDGPAGSAPDPSKWQVSNHRTPIRNPVGFDRPEFWGQY
MMAR_2902|M.marinum_M               ------YLFHDEFDGPAGSAPDSSKWTVARAREEMKDPTYWERPENVGQY
MAV_2761|M.avium_104                ------YLFQDEFDGPAGSAPDASKWAVAKARETIKDPTYWERPENIGQY
MSMEG_5345|M.smegmatis_MC2_155      ------YVFADEFDGPAGSAPSAAKWTIAKARETIQDPTYWEQPGRIGQY
MAB_4740|M.abscessus_ATCC_1997      ------YVFVDEFDGPAGSAPDGSKWAISKARETMKDPTFWELPENVGQY
TH_0196|M.thermoresistible__bu      ASGP-GLLFADEFDGPAGSPPDPAKWFIVPERETIRNPVEWDKPYNMGRY
Mvan_0446|M.vanbaalenii_PYR-1       AAVP-GLLFADEFNGPAGSPPNPAAWFIVPARETIRNPHEWDKPFNMGRY
Mflv_0298|M.gilvum_PYR-GCK          DAGP-LMLFQDEFDGPAGAPPDPARWFIVPARETIRNPVEWDKPFNMGRY
                                           :: ***:****: *. : * :   *  :::*  :: *   *:*

Mb0323|M.bovis_AF2122/97            RDSRQNVFLDGNSNLVLRATR-EGN----RYFGGLVHGLWRGGIGTTWEA
Rv0315|M.tuberculosis_H37Rv         RDSRQNVFLDGNSNLVLRATR-EGN----RYFGGLVHGLWRGGIGTTWEA
MUL_4744|M.ulcerans_Agy99           RDNRQNVFLDGNSNLVLRATR-SGN----DYFGGLVHGLWRGGIGTTWEA
MMAR_2902|M.marinum_M               RDDRQNVFLDGKSNLVIRAAK-DGG----TYYAGKIQSPWRGGIGHTWEA
MAV_2761|M.avium_104                RDDRRNVFLDGKSNLVLRAAK-DGP----TYYSGKVQSLWRGGVGHTWEA
MSMEG_5345|M.smegmatis_MC2_155      RNDRRNVFLDGKSNLVIRAAK-DGD----TYYSAKLASVWEGGAGHTWEA
MAB_4740|M.abscessus_ATCC_1997      RDDRKNVFLDGNSNLVIKAAK-EGN----TYYGGKIYSTTELGIGYTWEA
TH_0196|M.thermoresistible__bu      VTDQEHVFHDGNGNLVIRATRGPGANIREKYASAKIVGLWRGGVGTTWEA
Mvan_0446|M.vanbaalenii_PYR-1       VTDQEHVFQDGNGNLVIRATRGEGANIQEKYASAKIIGNWRGGVGTTWEA
Mflv_0298|M.gilvum_PYR-GCK          VTDQEHVFQDGNGNLVIRATRGEGTTIQEKYASAKIMGTWRGGIGTTWEA
                                      .:.:** **:.***::*::  *      * .. : .  . * * ****

Mb0323|M.bovis_AF2122/97            RIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPD
Rv0315|M.tuberculosis_H37Rv         RIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPD
MUL_4744|M.ulcerans_Agy99           RIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGSWPSGTTVHANPD
MMAR_2902|M.marinum_M               RIKFDCLTAGCWPAWWLGNQD---RGEIDIIEWYGNGSWPSATTVHAKAN
MAV_2761|M.avium_104                RIKLDCLTAGAWPAYWLGNDD---QGEIDVMEWYGNGNWPSATTVHAKAN
MSMEG_5345|M.smegmatis_MC2_155      RIKFNCLTAGAWPAFWLGNTG---EGELDIIEWYGNGSWPSATTVHAKSN
MAB_4740|M.abscessus_ATCC_1997      RIKFNCLTPGAWPAFWLGSDQ---DGEIDIVEWYGNGSWPSATTVHAKAN
TH_0196|M.thermoresistible__bu      RVKLNCLTDGAWPAFWLLNDDPVRGAEIDIFEWYGNRDWPSGATVHAKLD
Mvan_0446|M.vanbaalenii_PYR-1       RIKLNCLTDGAWPAFWLINDNPVRGGEVDLVEWYGNRDWPSGTTVHAKLD
Mflv_0298|M.gilvum_PYR-GCK          RVKLDCLTDGAWPAFWLVNENPVRGGEVDLVEWYGNNDWPSGTTVHARLD
                                    *:*::**: * ***:** .      .*:*:.*****  ***.:****. :

Mb0323|M.bovis_AF2122/97            GTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGIED
Rv0315|M.tuberculosis_H37Rv         GTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGIED
MUL_4744|M.ulcerans_Agy99           GTAFETFPIGVDDNWYNWRVTWNVTGMYFWLDYADGMQPYFSVPATGIED
MMAR_2902|M.marinum_M               GSEWKTRNVALDSGWHTWRCQWDETGMRFWQDYAEGAQPYFTVAAH----
MAV_2761|M.avium_104                GGEWKTHNIAVDSAWHTWRCQWDEAGIRFWKDYVDGAQPYFDVPAS----
MSMEG_5345|M.smegmatis_MC2_155      GGEWKTHNIAVDNGWHRWRTQWDAEGARFWLDYTDGAQPYFEVAAS----
MAB_4740|M.abscessus_ATCC_1997      GSEWKTHNISLDSGWHTWRTQWDDKGIRFWKDYTDGATPYFEVPAN----
TH_0196|M.thermoresistible__bu      GTMFQTQNYPVDSAWHTWRMTWLPSGMYFWQDYEPGKEPFFTVLAN----
Mvan_0446|M.vanbaalenii_PYR-1       GTMFQTHKHPIDSAWHTWRMTWLPTGMYFWKDYQPGMEPFFTVASN----
Mflv_0298|M.gilvum_PYR-GCK          GTAFATNRHPVDNAWHTWRMTWQPTGLYFWKDYQPGMEPFFTVPAN----
                                    *  : *    :*. *: **  *   *  ** **  *  *:* * :     

Mb0323|M.bovis_AF2122/97            LNEPIREWPFNDPGYTVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVRVF
Rv0315|M.tuberculosis_H37Rv         LNEPIREWPFNDPGYKVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVRVF
MUL_4744|M.ulcerans_Agy99           LNEPIREWPFNDPDYTVFPVLNLAVGGSGGGDPAAGTYPQEMLVDWVRVF
MMAR_2902|M.marinum_M               ---SLPDWPFNDPGYTVFPVLNLAVAGSGGGDPRPGSYPAQMLVDWVRVW
MAV_2761|M.avium_104                ---SLPDWPFNGPGYTVFPVFNLAVAGSGGGDPGPGSYPADMLIDWIRVW
MSMEG_5345|M.smegmatis_MC2_155      ---SLPDWPFDQPGYTMFVVLNLAVAGSGGGDPSGGTYPADMLVDWVRVW
MAB_4740|M.abscessus_ATCC_1997      ---SLADWPFNNPGHKAFAVLNLAVAGSGGGDPRGGTYPAEMLVDWIRVW
TH_0196|M.thermoresistible__bu      ---SLPEWPFNDPGYTMVPVFNIAVGGSGGREPAGGSYPADMIIDWIRVF
Mvan_0446|M.vanbaalenii_PYR-1       ---SLPDWPFNDPGYTMAPVFNIAVGGSGGREPAGGTYPAEMLVDWIRVF
Mflv_0298|M.gilvum_PYR-GCK          ---SIPDWPFNDPGFTMVPVFNIAVGGSGGREPAAGTYPAEMRVDWIRVF
                                       .: :***: *...   *:*:**.**** :*  *:** :* :**:**:

Mb0323|M.bovis_AF2122/97            --
Rv0315|M.tuberculosis_H37Rv         --
MUL_4744|M.ulcerans_Agy99           --
MMAR_2902|M.marinum_M               --
MAV_2761|M.avium_104                --
MSMEG_5345|M.smegmatis_MC2_155      --
MAB_4740|M.abscessus_ATCC_1997      --
TH_0196|M.thermoresistible__bu      --
Mvan_0446|M.vanbaalenii_PYR-1       --
Mflv_0298|M.gilvum_PYR-GCK          AS