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MDRRRMMAFSGLGMLAAAASMPQAWAQPSPLGPPNRPPAAPPTGKYVFVDEFDGPAGSAPDGSKWAISKA RETMKDPTFWELPENVGQYRDDRKNVFLDGNSNLVIKAAKEGNTYYGGKIYSTTELGIGYTWEARIKFNC LTPGAWPAFWLGSDQDGEIDIVEWYGNGSWPSATTVHAKANGSEWKTHNISLDSGWHTWRTQWDDKGIRF WKDYTDGATPYFEVPANSLADWPFNNPGHKAFAVLNLAVAGSGGGDPRGGTYPAEMLVDWIRVW
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_4740 | - | - | 100% (274) | beta-1,3-glucanase |
M. abscessus ATCC 19977 | MAB_1840c | - | 1e-98 | 60.67% (267) | putative beta-glucanase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0323 | - | 9e-99 | 57.44% (289) | beta-1,3-glucanase precursor |
M. gilvum PYR-GCK | Mflv_0298 | - | 2e-84 | 52.13% (282) | glycoside hydrolase family protein |
M. tuberculosis H37Rv | Rv0315 | - | 2e-99 | 57.79% (289) | beta-1,3-glucanase precursor |
M. leprae Br4923 | - | - | - | - | - |
M. marinum M | MMAR_2902 | - | 1e-121 | 70.44% (274) | beta-1,3-glucanase precursor |
M. avium 104 | MAV_2761 | - | 1e-124 | 70.29% (276) | glycosyl hydrolases family protein 16 |
M. smegmatis MC2 155 | MSMEG_5345 | - | 1e-117 | 67.52% (274) | glycosyl hydrolases family protein 16 |
M. thermoresistible (build 8) | TH_0196 | - | 5e-84 | 51.58% (285) | POSSIBLE BETA-1,3-GLUCANASE PRECURSOR |
M. ulcerans Agy99 | MUL_4744 | - | 1e-94 | 55.05% (287) | beta-1,3-glucanase precursor |
M. vanbaalenii PYR-1 | Mvan_0446 | - | 2e-86 | 54.67% (289) | glycoside hydrolase family protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb0323|M.bovis_AF2122/97 MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAPA Rv0315|M.tuberculosis_H37Rv MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAPA MUL_4744|M.ulcerans_Agy99 MLMQEIDRRRIIMMAGFGALAAAIPAPTAGAAP---IPPAAPEPAPAAPA MMAR_2902|M.marinum_M --MPEMDRRRMMLMTGFGVLGAALPVPAASADSSRRDMPLAPAPNGQSGP MAV_2761|M.avium_104 --MPEIDRRRMIVTTGIGVLAAALPNPRAGASP----APPPAAPSGQSGT MSMEG_5345|M.smegmatis_MC2_155 --MANVDRRQMLLLSGLGATAAVLPVPRA-----------AAVPNQTAAS MAB_4740|M.abscessus_ATCC_1997 -----MDRRRMMAFSGLGMLAAAASMPQAWAQPSPLGPPNRPPAAPPTGK TH_0196|M.thermoresistible__bu --MPMMNRRQAMMMLGFGAVAAALPLPQAGAQPVL-DAPAPGPDTP--EA Mvan_0446|M.vanbaalenii_PYR-1 -----MDRRRAMLTLGFGMAAAALPFPKAGAQPVIGDAPPPGPSGPGLPE Mflv_0298|M.gilvum_PYR-GCK --MPEMDRRKAMLMMGLGAAVVASPLGSAHAQ------PPAVPSEPLPAG ::**: : *:* .. . * Mb0323|M.bovis_AF2122/97 AATG-GLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQY Rv0315|M.tuberculosis_H37Rv AATG-GLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQY MUL_4744|M.ulcerans_Agy99 AGAGPIFLWHDEFDGPAGSAPDPSKWQVSNHRTPIRNPVGFDRPEFWGQY MMAR_2902|M.marinum_M ------YLFHDEFDGPAGSAPDSSKWTVARAREEMKDPTYWERPENVGQY MAV_2761|M.avium_104 ------YLFQDEFDGPAGSAPDASKWAVAKARETIKDPTYWERPENIGQY MSMEG_5345|M.smegmatis_MC2_155 ------YVFADEFDGPAGSAPSAAKWTIAKARETIQDPTYWEQPGRIGQY MAB_4740|M.abscessus_ATCC_1997 ------YVFVDEFDGPAGSAPDGSKWAISKARETMKDPTFWELPENVGQY TH_0196|M.thermoresistible__bu ASGP-GLLFADEFDGPAGSPPDPAKWFIVPERETIRNPVEWDKPYNMGRY Mvan_0446|M.vanbaalenii_PYR-1 AAVP-GLLFADEFNGPAGSPPNPAAWFIVPARETIRNPHEWDKPFNMGRY Mflv_0298|M.gilvum_PYR-GCK DAGP-LMLFQDEFDGPAGAPPDPARWFIVPARETIRNPVEWDKPFNMGRY :: ***:****: *. : * : * :::* :: * *:* Mb0323|M.bovis_AF2122/97 RDSRQNVFLDGNSNLVLRATR-EGN----RYFGGLVHGLWRGGIGTTWEA Rv0315|M.tuberculosis_H37Rv RDSRQNVFLDGNSNLVLRATR-EGN----RYFGGLVHGLWRGGIGTTWEA MUL_4744|M.ulcerans_Agy99 RDNRQNVFLDGNSNLVLRATR-SGN----DYFGGLVHGLWRGGIGTTWEA MMAR_2902|M.marinum_M RDDRQNVFLDGKSNLVIRAAK-DGG----TYYAGKIQSPWRGGIGHTWEA MAV_2761|M.avium_104 RDDRRNVFLDGKSNLVLRAAK-DGP----TYYSGKVQSLWRGGVGHTWEA MSMEG_5345|M.smegmatis_MC2_155 RNDRRNVFLDGKSNLVIRAAK-DGD----TYYSAKLASVWEGGAGHTWEA MAB_4740|M.abscessus_ATCC_1997 RDDRKNVFLDGNSNLVIKAAK-EGN----TYYGGKIYSTTELGIGYTWEA TH_0196|M.thermoresistible__bu VTDQEHVFHDGNGNLVIRATRGPGANIREKYASAKIVGLWRGGVGTTWEA Mvan_0446|M.vanbaalenii_PYR-1 VTDQEHVFQDGNGNLVIRATRGEGANIQEKYASAKIIGNWRGGVGTTWEA Mflv_0298|M.gilvum_PYR-GCK VTDQEHVFQDGNGNLVIRATRGEGTTIQEKYASAKIMGTWRGGIGTTWEA .:.:** **:.***::*:: * * .. : . . * * **** Mb0323|M.bovis_AF2122/97 RIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPD Rv0315|M.tuberculosis_H37Rv RIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPD MUL_4744|M.ulcerans_Agy99 RIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGSWPSGTTVHANPD MMAR_2902|M.marinum_M RIKFDCLTAGCWPAWWLGNQD---RGEIDIIEWYGNGSWPSATTVHAKAN MAV_2761|M.avium_104 RIKLDCLTAGAWPAYWLGNDD---QGEIDVMEWYGNGNWPSATTVHAKAN MSMEG_5345|M.smegmatis_MC2_155 RIKFNCLTAGAWPAFWLGNTG---EGELDIIEWYGNGSWPSATTVHAKSN MAB_4740|M.abscessus_ATCC_1997 RIKFNCLTPGAWPAFWLGSDQ---DGEIDIVEWYGNGSWPSATTVHAKAN TH_0196|M.thermoresistible__bu RVKLNCLTDGAWPAFWLLNDDPVRGAEIDIFEWYGNRDWPSGATVHAKLD Mvan_0446|M.vanbaalenii_PYR-1 RIKLNCLTDGAWPAFWLINDNPVRGGEVDLVEWYGNRDWPSGTTVHAKLD Mflv_0298|M.gilvum_PYR-GCK RVKLDCLTDGAWPAFWLVNENPVRGGEVDLVEWYGNNDWPSGTTVHARLD *:*::**: * ***:** . .*:*:.***** ***.:****. : Mb0323|M.bovis_AF2122/97 GTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGIED Rv0315|M.tuberculosis_H37Rv GTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGIED MUL_4744|M.ulcerans_Agy99 GTAFETFPIGVDDNWYNWRVTWNVTGMYFWLDYADGMQPYFSVPATGIED MMAR_2902|M.marinum_M GSEWKTRNVALDSGWHTWRCQWDETGMRFWQDYAEGAQPYFTVAAH---- MAV_2761|M.avium_104 GGEWKTHNIAVDSAWHTWRCQWDEAGIRFWKDYVDGAQPYFDVPAS---- MSMEG_5345|M.smegmatis_MC2_155 GGEWKTHNIAVDNGWHRWRTQWDAEGARFWLDYTDGAQPYFEVAAS---- MAB_4740|M.abscessus_ATCC_1997 GSEWKTHNISLDSGWHTWRTQWDDKGIRFWKDYTDGATPYFEVPAN---- TH_0196|M.thermoresistible__bu GTMFQTQNYPVDSAWHTWRMTWLPSGMYFWQDYEPGKEPFFTVLAN---- Mvan_0446|M.vanbaalenii_PYR-1 GTMFQTHKHPIDSAWHTWRMTWLPTGMYFWKDYQPGMEPFFTVASN---- Mflv_0298|M.gilvum_PYR-GCK GTAFATNRHPVDNAWHTWRMTWQPTGLYFWKDYQPGMEPFFTVPAN---- * : * :*. *: ** * * ** ** * *:* * : Mb0323|M.bovis_AF2122/97 LNEPIREWPFNDPGYTVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVRVF Rv0315|M.tuberculosis_H37Rv LNEPIREWPFNDPGYKVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVRVF MUL_4744|M.ulcerans_Agy99 LNEPIREWPFNDPDYTVFPVLNLAVGGSGGGDPAAGTYPQEMLVDWVRVF MMAR_2902|M.marinum_M ---SLPDWPFNDPGYTVFPVLNLAVAGSGGGDPRPGSYPAQMLVDWVRVW MAV_2761|M.avium_104 ---SLPDWPFNGPGYTVFPVFNLAVAGSGGGDPGPGSYPADMLIDWIRVW MSMEG_5345|M.smegmatis_MC2_155 ---SLPDWPFDQPGYTMFVVLNLAVAGSGGGDPSGGTYPADMLVDWVRVW MAB_4740|M.abscessus_ATCC_1997 ---SLADWPFNNPGHKAFAVLNLAVAGSGGGDPRGGTYPAEMLVDWIRVW TH_0196|M.thermoresistible__bu ---SLPEWPFNDPGYTMVPVFNIAVGGSGGREPAGGSYPADMIIDWIRVF Mvan_0446|M.vanbaalenii_PYR-1 ---SLPDWPFNDPGYTMAPVFNIAVGGSGGREPAGGTYPAEMLVDWIRVF Mflv_0298|M.gilvum_PYR-GCK ---SIPDWPFNDPGFTMVPVFNIAVGGSGGREPAAGTYPAEMRVDWIRVF .: :***: *... *:*:**.**** :* *:** :* :**:**: Mb0323|M.bovis_AF2122/97 -- Rv0315|M.tuberculosis_H37Rv -- MUL_4744|M.ulcerans_Agy99 -- MMAR_2902|M.marinum_M -- MAV_2761|M.avium_104 -- MSMEG_5345|M.smegmatis_MC2_155 -- MAB_4740|M.abscessus_ATCC_1997 -- TH_0196|M.thermoresistible__bu -- Mvan_0446|M.vanbaalenii_PYR-1 -- Mflv_0298|M.gilvum_PYR-GCK AS