For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. bovis AF2122 / 97 Mb0323 (-)

annotation: beta-1,3-glucanase precursor
coordinates: 384632 - 385516
length: 294

MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAPAAATGGLLFHDEFDGPAGSVP
DPSKWQVSNHRTPIKNPVGFDRPQFFGQYRDSRQNVFLDGNSNLVLRATREGNRYFGGLVHGLWRGGIGT
TWEARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPDGTAFETCPIGVDGGWH
NWRVTWNPSGMYFWLDYADGIEPYFSVPATGIEDLNEPIREWPFNDPGYTVFPVLNLAVGGSGGGDPATG
SYPQEMLVDWVRVF
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0323--100% (294)beta-1,3-glucanase precursor

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0298-2e-9755.56% (297) glycoside hydrolase family protein
M. tuberculosis H37RvRv0315-0.099.66% (294) beta-1,3-glucanase precursor
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1840c-1e-10763.08% (279) putative beta-glucanase
M. marinum MMMAR_0567-1e-16187.46% (295) beta-1,3-glucanase precursor
M. avium 104MAV_2761-1e-10458.56% (292) glycosyl hydrolases family protein 16
M. smegmatis MC2 155MSMEG_0645-6e-9858.13% (289) putative beta-1,3-glucanase
M. thermoresistible (build 8)TH_0196-1e-10158.05% (298) POSSIBLE BETA-1,3-GLUCANASE PRECURSOR
M. ulcerans Agy99MUL_4744-1e-16087.12% (295) beta-1,3-glucanase precursor
M. vanbaalenii PYR-1Mvan_0446-2e-9756.46% (294) glycoside hydrolase family protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_0196|M.thermoresistible__bu      --MPMMNRRQAMMMLGFGAVAAALPLPQAGAQPVL----DAPAPGPDTP-
Mvan_0446|M.vanbaalenii_PYR-1       -----MDRRRAMLTLGFGMAAAALPFPKAGAQPVIG---DAPPPGPSGPG
Mflv_0298|M.gilvum_PYR-GCK          --MPEMDRRKAMLMMGLGAAVVASPLGSAHAQPPA-----VPSEP--LP-
MSMEG_0645|M.smegmatis_MC2_155      ----------MMFMMGLGVAAAALPVGTAGADPLIG---DNPPGP--GP-
Mb0323|M.bovis_AF2122/97            MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAP-
Rv0315|M.tuberculosis_H37Rv         MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAP-
MMAR_0567|M.marinum_M               MLMQEIDRRRMIMMAGFGALAAAIPAPTAGAAP---TPPAAPEPAPAAP-
MUL_4744|M.ulcerans_Agy99           MLMQEIDRRRIIMMAGFGALAAAIPAPTAGAAP---IPPAAPEPAPAAP-
MAV_2761|M.avium_104                --MPEIDRRRMIVTTGIGVLAAALPNPRAGASP---------APPPAAP-
MAB_1840c|M.abscessus_ATCC_199      --------------MGFGMAAAALPLPKAQADR---------VHPPAAP-
                                                   *:*  ..* *   * *                 * 

TH_0196|M.thermoresistible__bu      -EAASGPGLLFADEFDGPAGSPPDPAKWFIVPERETIRNPVEWDKPYNMG
Mvan_0446|M.vanbaalenii_PYR-1       LPEAAVPGLLFADEFNGPAGSPPNPAAWFIVPARETIRNPHEWDKPFNMG
Mflv_0298|M.gilvum_PYR-GCK          -AGDAGPLMLFQDEFDGPAGAPPDPARWFIVPARETIRNPVEWDKPFNMG
MSMEG_0645|M.smegmatis_MC2_155      -AAAAEPTFLFQDEFNGPAGSPPDPAWWYLVPARETIKNPVEWDKPYNMG
Mb0323|M.bovis_AF2122/97            -AAATG-GLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFG
Rv0315|M.tuberculosis_H37Rv         -AAATG-GLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFG
MMAR_0567|M.marinum_M               -AAGAGPIFLWHDEFDGPAGSAPDPAKWQVSNHRTPIRNPVGFDRPEFWG
MUL_4744|M.ulcerans_Agy99           -AAGAGPIFLWHDEFDGPAGSAPDPSKWQVSNHRTPIRNPVGFDRPEFWG
MAV_2761|M.avium_104                -SGQSG-TYLFQDEFDGPAGSAPDASKWAVAKARETIKDPTYWERPENIG
MAB_1840c|M.abscessus_ATCC_199      -PDAQSSGFVFRDEFDGPAGSAPDGSKWVAAKFRERIKNPVFWDRPENMG
                                             :: ***:****: *: : *     *  *::*  :::*   *

TH_0196|M.thermoresistible__bu      RYVTDQEHVFHDGNGNLVIRATRGPGANIREKYASAKIVGLWRGGVGTTW
Mvan_0446|M.vanbaalenii_PYR-1       RYVTDQEHVFQDGNGNLVIRATRGEGANIQEKYASAKIIGNWRGGVGTTW
Mflv_0298|M.gilvum_PYR-GCK          RYVTDQEHVFQDGNGNLVIRATRGEGTTIQEKYASAKIMGTWRGGIGTTW
MSMEG_0645|M.smegmatis_MC2_155      RYVTDQEHAFQDGKGNLVIRATRGPGTTIQEKYASAKVVGLWRGGIGTTW
Mb0323|M.bovis_AF2122/97            QYRDSRQNVFLDGNSNLVLRATR-EGN----RYFGGLVHGLWRGGIGTTW
Rv0315|M.tuberculosis_H37Rv         QYRDSRQNVFLDGNSNLVLRATR-EGN----RYFGGLVHGLWRGGIGTTW
MMAR_0567|M.marinum_M               QYRDNRQNVFLDGNSNLVLRATR-SGN----DYFGGLVHGLWRGGIGTTW
MUL_4744|M.ulcerans_Agy99           QYRDNRQNVFLDGNSNLVLRATR-SGN----DYFGGLVHGLWRGGIGTTW
MAV_2761|M.avium_104                QYRDDRRNVFLDGKSNLVLRAAK-DGP----TYYSGKVQSLWRGGVGHTW
MAB_1840c|M.abscessus_ATCC_199      EYRDSRTNIFLDGNSNLVIRATK-EGN----KYFSGKLHGTFRGGMGHTF
                                    .*  .: : * **:.***:**::  *      * .. : . :***:* *:

TH_0196|M.thermoresistible__bu      EARVKLNCLTDGAWPAFWLLNDDPVRGAEIDIFEWYGNRDWPSGATVHAK
Mvan_0446|M.vanbaalenii_PYR-1       EARIKLNCLTDGAWPAFWLINDNPVRGGEVDLVEWYGNRDWPSGTTVHAK
Mflv_0298|M.gilvum_PYR-GCK          EARVKLDCLTDGAWPAFWLVNENPVRGGEVDLVEWYGNNDWPSGTTVHAR
MSMEG_0645|M.smegmatis_MC2_155      EARVKLNCLTDGAWPAFWLLNDNPVRGGEVDLVEWYGNRDWPSGTTVHAR
Mb0323|M.bovis_AF2122/97            EARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHAN
Rv0315|M.tuberculosis_H37Rv         EARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHAN
MMAR_0567|M.marinum_M               EARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGSWPSGTTVHAN
MUL_4744|M.ulcerans_Agy99           EARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGSWPSGTTVHAN
MAV_2761|M.avium_104                EARIKLDCLTAGAWPAYWLGNDD---QGEIDVMEWYGNGNWPSATTVHAK
MAB_1840c|M.abscessus_ATCC_199      EARIKFNCLTDGCWPAWWLLNDNPERGGEIDMAEWYGNRDWPSGTTVHAR
                                    ***:*::**: * ***:** *::    .*:*: *****  ***.:****.

TH_0196|M.thermoresistible__bu      LDGTMFQTQNYPVDSAWHTWRMTWLPSGMYFWQDYEPGKEPFFTVLAN--
Mvan_0446|M.vanbaalenii_PYR-1       LDGTMFQTHKHPIDSAWHTWRMTWLPTGMYFWKDYQPGMEPFFTVASN--
Mflv_0298|M.gilvum_PYR-GCK          LDGTAFATNRHPVDNAWHTWRMTWQPTGLYFWKDYQPGMEPFFTVPAN--
MSMEG_0645|M.smegmatis_MC2_155      LDGTSFATNPHPVDSDWHTWRMSWKPEGMYFWKDYAPGMEPFFSVPAN--
Mb0323|M.bovis_AF2122/97            PDGTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGI
Rv0315|M.tuberculosis_H37Rv         PDGTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGI
MMAR_0567|M.marinum_M               PDGTAFETFPIGVDDNWHNWRVTWNVTGMYFWLDYADGMQPYFSVPATGI
MUL_4744|M.ulcerans_Agy99           PDGTAFETFPIGVDDNWYNWRVTWNVTGMYFWLDYADGMQPYFSVPATGI
MAV_2761|M.avium_104                ANGGEWKTHNIAVDSAWHTWRCQWDEAGIRFWKDYVDGAQPYFDVPAS--
MAB_1840c|M.abscessus_ATCC_199      LDGTSFETLPVPIDSNWHTWRCTWTEAGLYFWMDYHDGMEPYLTVDAN--
                                     :*  : *    :*. *:.**  *   *: ** **  * :*:: * :.  

TH_0196|M.thermoresistible__bu      -----SLPEWPFNDPGYTMVPVFNIAVGGSGGREPAGGSYPADMIIDWIR
Mvan_0446|M.vanbaalenii_PYR-1       -----SLPDWPFNDPGYTMAPVFNIAVGGSGGREPAGGTYPAEMLVDWIR
Mflv_0298|M.gilvum_PYR-GCK          -----SIPDWPFNDPGFTMVPVFNIAVGGSGGREPAAGTYPAEMRVDWIR
MSMEG_0645|M.smegmatis_MC2_155      -----SLQDWPFNDPGYTMVPVFNIAVGGSGGREPAGGTYPAEMLVDWIR
Mb0323|M.bovis_AF2122/97            EDLNEPIREWPFNDPGYTVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVR
Rv0315|M.tuberculosis_H37Rv         EDLNEPIREWPFNDPGYKVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVR
MMAR_0567|M.marinum_M               EDLNEPIREWPFNDPDYTVFPVLNLAVGGSGGGDPAAGTYPQEMLVDWVR
MUL_4744|M.ulcerans_Agy99           EDLNEPIREWPFNDPDYTVFPVLNLAVGGSGGGDPAAGTYPQEMLVDWVR
MAV_2761|M.avium_104                -----SLPDWPFNGPGYTVFPVFNLAVAGSGGGDPGPGSYPADMLIDWIR
MAB_1840c|M.abscessus_ATCC_199      -----SLDDWPFNDPGYTLQPMLNLAVAGSGGGDPAGGSYPAEMLVDYVR
                                         .: :****.*.:.: *::*:**.**** :*. *:** :* :*::*

TH_0196|M.thermoresistible__bu      VF--
Mvan_0446|M.vanbaalenii_PYR-1       VF--
Mflv_0298|M.gilvum_PYR-GCK          VFAS
MSMEG_0645|M.smegmatis_MC2_155      VFAG
Mb0323|M.bovis_AF2122/97            VF--
Rv0315|M.tuberculosis_H37Rv         VF--
MMAR_0567|M.marinum_M               VF--
MUL_4744|M.ulcerans_Agy99           VF--
MAV_2761|M.avium_104                VW--
MAB_1840c|M.abscessus_ATCC_199      VW--
                                    *: