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FESLFDVGVGASEAELRAAVERCERLKSQAAAAQARATALWAAQRRAAEQAGGVPAARRGKGLASEVALA RHDAPVLGNRHLGFAQALVEEMPHTLAALECGALSEWRATLIVRESACLSVEHRRALDEELCGDVSRLAG WGNKRVEAEAKTIAARLDAAAVVDHTEKAAADCAVTCRPAPNNMVYVTLRLPLTRGVGIYAACKRAADTT FDGRPRGQVMTDTVYERVTGRAADTPVPVALNLVMADTTLAGDDDELGWLDGYGPVPAGFCRALIGNAVA DAHAHADADADADAEVDAEVKATLRRLYRHPTSGQLVAMESRARIFPKGLGMERVKFFV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2657 | - | - | 100% (340) | hypothetical protein Mvan_2657 |
| M. vanbaalenii PYR-1 | Mvan_3614 | - | 0.0 | 97.60% (333) | hypothetical protein Mvan_3614 |
| M. vanbaalenii PYR-1 | Mvan_5297 | - | e-172 | 92.19% (333) | hypothetical protein Mvan_5297 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3101 | - | 1e-100 | 59.21% (331) | hypothetical protein Mb3101 |
| M. gilvum PYR-GCK | Mflv_2586 | - | 1e-138 | 75.83% (331) | hypothetical protein Mflv_2586 |
| M. tuberculosis H37Rv | Rv3074 | - | 1e-100 | 59.21% (331) | hypothetical protein Rv3074 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1907 | - | 3e-81 | 50.63% (318) | hypothetical protein MAB_1907 |
| M. marinum M | MMAR_1584 | - | 1e-101 | 58.61% (331) | hypothetical protein MMAR_1584 |
| M. avium 104 | MAV_3980 | - | 1e-101 | 59.88% (324) | hypothetical protein MAV_3980 |
| M. smegmatis MC2 155 | MSMEG_6025 | - | 1e-108 | 61.93% (331) | hypothetical protein MSMEG_6025 |
| M. thermoresistible (build 8) | TH_0334 | - | 2e-07 | 24.10% (332) | HNH endonuclease |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2657|M.vanbaalenii_PYR-1 ----------MFESLFDVGVGASEAELRAAVERCERLKSQAAAAQARATA
Mflv_2586|M.gilvum_PYR-GCK ----------MFESLFDIDEGASQAELRAVVERCERLKSAAAAAQARATA
MSMEG_6025|M.smegmatis_MC2_155 MSVRGCSVWHMFESLFDIDPQASEAELRDRIEQFERMKSAAAAAQATASV
Mb3101|M.bovis_AF2122/97 ----------MFETLTAIDPDAEEAALIERIAELERLKSAAAAGQARAAA
Rv3074|M.tuberculosis_H37Rv ----------MFETLTAIDPDAEEAALIERIAELERLKSAAAAGQARAAA
MMAR_1584|M.marinum_M ----------MFESLAAVDPAADQAALVERIAELETVKSAAAAGQARAAA
MAV_3980|M.avium_104 ---------------MAVDPAAGESALIERISELETLKCAAAAAQARAAA
MAB_1907|M.abscessus_ATCC_1997 --------------MLPLDPATRAAQLVDRIAELERVKAAAAAEQAHAAV
TH_0334|M.thermoresistible__bu -----------------MFESLDDGAVVDSIAAASREQSAACGREMLAIG
: . : : . :. *.. : *
Mvan_2657|M.vanbaalenii_PYR-1 LWAAQRRAAEQAGGVPAARRGKG-LASEVALARHDAPVLGNRHLGFAQAL
Mflv_2586|M.gilvum_PYR-GCK LWAAKRAAAEEAAGVPVRRRGKG-LASEVALARRDAPVKGGQHLGFAKAL
MSMEG_6025|M.smegmatis_MC2_155 LWEQKRRAAEAAAGIPASRRGRG-LATEVALARRESPNAGGRHLGLAHAL
Mb3101|M.bovis_AF2122/97 AVDAARRAAEGAAGVPAARRGRG-LASEIALARRDSPARGSRHLGFAKAL
Rv3074|M.tuberculosis_H37Rv AVDAARRAAEGAAGVPAARRGRG-LASEIALARRDSPARGSRHLGFAKAL
MMAR_1584|M.marinum_M ALDTARRAAESAAGVPAARRGRG-LANEIALARRDSPARGSRHLGFAKAL
MAV_3980|M.avium_104 ALDAARRAAEAAAGVPAARRGRG-VASEVALARRDSPARGGRHLGFAKAL
MAB_1907|M.abscessus_ATCC_1997 LLDRARREEEAANGVPRRRQGAG-VATEIALARQDSPARGSRHLGFAKAL
TH_0334|M.thermoresistible__bu ELYARRAPEDDTERANWAIDGHANVVAEISAALNISRGRAAGRLQLAIDL
* : : * . :. *:: * . : . :* :* *
Mvan_2657|M.vanbaalenii_PYR-1 VEEMPHTLAALECGALSEWRATLIVRES-ACLSVEHRRALDEELCGDVSR
Mflv_2586|M.gilvum_PYR-GCK MGEMPHTWAALECGALSEWRATLIVRES-ACLSVEDRRRLDEELCADVSR
MSMEG_6025|M.smegmatis_MC2_155 VDELPHTLAALRCGALSEWRATLIARES-ACLSPELRRELDAELSADPSR
Mb3101|M.bovis_AF2122/97 VYEMPHTLAALDCGALSEWRATLIVRES-ACLDVADRRALDAELCGDPGD
Rv3074|M.tuberculosis_H37Rv VYEMPHTLAALDCGALSEWRATLIVRES-ACLDVADRRALDAELCGDPGD
MMAR_1584|M.marinum_M VHEMPHTLAALECGLLSEWRATLIVRES-ACLDIEHRRELDAELCGDPSG
MAV_3980|M.avium_104 VHEMPHTLAALECGALSEWRATLIVRES-ACLDAEDRRALDAELCADPAG
MAB_1907|M.abscessus_ATCC_1997 VNEMPHTLAALECGALSEWRATILVRET-AYLAVEDRQKIDVEMCAETSR
TH_0334|M.thermoresistible__bu RERLPRVAAVFAAGDIDFRMVSALVNRSRNVVDPDLLARLDAALAAWSPK
.:*:. *.: .* :. .: :...: : :* :..
Mvan_2657|M.vanbaalenii_PYR-1 LAGWGNKRVEAEAKTIAARLDAAAVVDHTEKAAADCAVTCRPAPNNMVYV
Mflv_2586|M.gilvum_PYR-GCK FEGWGNKRVEAEAKKIAARLDVAAVVERVDRAAAQARVSCRPAPNGMVYF
MSMEG_6025|M.smegmatis_MC2_155 FDGWGDARVAAEAKKIACRLNIDAVLDRSAKAEKDRRVTIRPAPDAMTKL
Mb3101|M.bovis_AF2122/97 LEGMGDARVVAAARAIAYRLDPQAVVDRAANAENDRTVTIRPAPDTMTYL
Rv3074|M.tuberculosis_H37Rv LEGMGDARVVAAARAIAYRLDPQAVVDRAANAENDRTVTIRPAPDTMTYL
MMAR_1584|M.marinum_M LEGMGDARVAAAAKAIAYRLDPHAVVDRAAKAERERTVTIRPAPDTMTYL
MAV_3980|M.avium_104 LSGMGDARVAAAAKAIAYRLDPHAVVERAAKAENDRTVTIRPAPDTMTYL
MAB_1907|M.abscessus_ATCC_1997 LRGLGDTRLAAEAKRLAYRLDAQAVVRRARRAESERRVSLRPAPDTMTYL
TH_0334|M.thermoresistible__bu WMKLSGPTLNERIDMWVERFDPTGVREPRSPGE-DRYVVVTPAGQGMVDV
.. : . *:: .* . : * ** : *. .
Mvan_2657|M.vanbaalenii_PYR-1 TLRLPLTRGVGIYAACKRAADTTFD--GRPRGQVMTDTVYERVTGR----
Mflv_2586|M.gilvum_PYR-GCK TVLLPLAQGIGMYAALKHHADTTFD--GRSRGQVMADTAFERITGR----
MSMEG_6025|M.smegmatis_MC2_155 TVLLPLKQGVAVYAALHQAAMVNAD--DRNRGQVMADTLVERVTGR----
Mb3101|M.bovis_AF2122/97 TALLPVAQGVSVYAALTRAADTRCD--GRSRGQVMADTLVERVTGR----
Rv3074|M.tuberculosis_H37Rv TALLPVAQGVSVYAALTRAADTRCD--GRSRGQVMADTLVERVTGR----
MMAR_1584|M.marinum_M TALLPVAQGISVYAALRRAADTRCD--GRSRGQVMADTLVERVTGR----
MAV_3980|M.avium_104 TALLPVAQGVSVYAALRREADTRGD--GRPRGQVMADTLVERVTGR----
MAB_1907|M.abscessus_ATCC_1997 TALLPVKQGVAVYAALKRTADASMDP-VRGQGQIMADTLVERVTGV----
TH_0334|M.thermoresistible__bu SARLTFEAGFAFXTRLDQIAATVCRDDPRTADQRRADAMAAMSEGQNRLV
: *.. *... : : * . * .* :*: *
Mvan_2657|M.vanbaalenii_PYR-1 ------------AADTPVPVALNLVMADTTLAGDDDELGWLDGYGPVPAG
Mflv_2586|M.gilvum_PYR-GCK ------------SAGTAVPVALNLVMADTTLAGDDDCPGWLDGYGPVPAG
MSMEG_6025|M.smegmatis_MC2_155 ------------PAHAPVPVNLNLVMADTTLFGEDDQPGWVQGYGPVPAE
Mb3101|M.bovis_AF2122/97 ------------DAAVPTPIAVNLVMSDETLLGAANTPAQLCGYGPIPAA
Rv3074|M.tuberculosis_H37Rv ------------DAAVPTPIAVNLVMSDETLLGAANTPAQLCGYGPIPAA
MMAR_1584|M.marinum_M ------------DAAVPTPIAVNLVLTDESLLGADSAPADVCGYGPIPAA
MAV_3980|M.avium_104 ------------RSTVPTPVAVNLVLSDETLLGGADAPGEISGYGPIPAA
MAB_1907|M.abscessus_ATCC_1997 ------------SAAAAVPVGVNITVSDEALLGGGDEPATITGHGLVPAA
TH_0334|M.thermoresistible__bu CGCGSEDCPADPADTAATRLVINVIAEQATVEGRSDNPGYLPGYGAVPAS
... : :*: : :: * . . : *:* :**
Mvan_2657|M.vanbaalenii_PYR-1 FCRALIGNAVADAHAHADADADADAEVDAEVKATLRRLYRHPTSGQLVAM
Mflv_2586|M.gilvum_PYR-GCK FCRALTGDAVADKGAR----------------ATLRRLYRHPRSGQLVAM
MSMEG_6025|M.smegmatis_MC2_155 VARRMVADATLDENTK----------------AAVRRLFRHPKSGQLVAM
Mb3101|M.bovis_AF2122/97 VARTMVASAVTDQRSR----------------ATLRRLYAHPQAGALVSM
Rv3074|M.tuberculosis_H37Rv VARTMVASAVTDQRSR----------------ATLRRLYAHPQAGALVSM
MMAR_1584|M.marinum_M VARTMVADAVADGRSR----------------ATLRRLYAHPRAGALVAM
MAV_3980|M.avium_104 VARRMVANAAADPRSR----------------ATLRRLYAHPRAGALVAM
MAB_1907|M.abscessus_ATCC_1997 VARRLISEAVS-AEAK----------------VLVRRLYRRCTTGALVKA
TH_0334|M.thermoresistible__bu ILRAKAATATLRPVAL-------------------------PQPCAEAGY
. * . *. : . .
Mvan_2657|M.vanbaalenii_PYR-1 ESRARIFPKGLG--MERVKFFV----------------------------
Mflv_2586|M.gilvum_PYR-GCK ESRARLFPKGLATLIDRRDQTCRTPYCDAP--IRHHDHATPDRAGGKTSA
MSMEG_6025|M.smegmatis_MC2_155 ESRSRIFPKGLATFIGLRDQTCRTPYCDAL--IRHRDHAVPHHDGGPTTA
Mb3101|M.bovis_AF2122/97 ESRARLFPRGLAAFIELRDQRCRTPYCDAP--IRHRDHAHPWADGGPTSA
Rv3074|M.tuberculosis_H37Rv ESRARLFPRGLAAFIELRDQRCRTPYCDAP--IRHRDHAHPWADGGPTSA
MMAR_1584|M.marinum_M ESRARLFPRGLAAFIELRDQRCRTPYCDAP--IRHRDHARPWAKGGPTTA
MAV_3980|M.avium_104 ESRARLFPQGLARFIGLRDQRCRTPYCDAP--IRHRDHAQPWADGGATSA
MAB_1907|M.abscessus_ATCC_1997 ESRSRLFPRGLAELIDLRDQTCRTPYCDAP--IRHHDHVVGSMRGGPTAL
TH_0334|M.thermoresistible__bu RP-----SAALTRFIRCRDLTCRFPGCDAPAAVCQIDHTIPYPAGPTHPS
.. . .* : .
Mvan_2657|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2586|M.gilvum_PYR-GCK ENGLGECAACNYAKEAPGWQVSA-GTQDGSHTARWVTPTGAVHYSIAPAL
MSMEG_6025|M.smegmatis_MC2_155 HNGLGTCEACNYAKEAPGWSVIITETSDGEHIAEYVTPTGAVYRSTAPPL
Mb3101|M.bovis_AF2122/97 HNGLGTCERCNYAKQAPGWRVSTSVDENHTHTAEFITPTGSRHRSGAPPH
Rv3074|M.tuberculosis_H37Rv HNGLGTCERCNYAKQAPGWRVSTSVDENHTHTAEFITPTGSRHRSGAPPH
MMAR_1584|M.marinum_M DNGLGSCERCNYAKEAYGWRVETSMHETHTHTAEFTTPTGTSYRSGAPPR
MAV_3980|M.avium_104 GNGLGLCEHCNYVKETSGWTVSAGVDETHTHTALFTTPTGQTYRSTAPPR
MAB_1907|M.abscessus_ATCC_1997 DNGQGLCERCNYVKETAGWNVAP-VPGADRHTVEFTTPTGTAYRSTAPPL
TH_0334|M.thermoresistible__bu NLKLLCVFHCRQAELR--FTHDQHKHQSSCLPAYFQRPHGPATRRPPSAR
Mvan_2657|M.vanbaalenii_PYR-1 -----------------------------
Mflv_2586|M.gilvum_PYR-GCK PGPPVRRRISDTEGRLSIDLITFDKPDAA
MSMEG_6025|M.smegmatis_MC2_155 PGRPVRHTLSLVETGLTIDLVTFDAA---
Mb3101|M.bovis_AF2122/97 LPAVT---VSELEVRIGIALARYAA----
Rv3074|M.tuberculosis_H37Rv LPAVT---VSELEVRIGIALARYAA----
MMAR_1584|M.marinum_M VQTVT---ASELEVRVGISLARHAA----
MAV_3980|M.avium_104 APAIT---MSTVEVRVAVAFARHAA----
MAB_1907|M.abscessus_ATCC_1997 P----------------------------
TH_0334|M.thermoresistible__bu G-------LREAVPRQGVDPRRVSGQ---