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ATVRFSGVNKAYGTTSVVSDLDLELPDGSFTVLVGPSGCGKSTSLRMLAGLETVTSGSITIGARDVTHLQ PRDRDIAMVFQNYALYPHLTVAENIAFPLRATKTPRREALTRAATIAESLGLAKLLDRKPKDLSGGQQQR VAIGRAIIREPSVFLFDEPLSNLDAKLRVETRTELLQIQRRLGITSVYVTHDQEEAMTLSDRMVVMRDGR IAQQGTPQEVYARPADTFVAAFVGSPKMNLIDGAVSGTTFTVGDGFALTVDQTAAGGPVTLGVRPDDLLP TVSDGDGAARVILIEHLGPRAIVTIDARGTELTSVVETSRLSGITEGTPVDLAVRPGATHFFDPATGSRL SG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2621 | - | - | 100% (353) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_4484 | - | 2e-79 | 46.25% (387) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2541 | - | 1e-78 | 45.10% (388) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2856c | ugpC | 8e-85 | 49.03% (361) | sn-glycerol-3-phosphate transport ATP-binding protein ABC |
| M. gilvum PYR-GCK | Mflv_3778 | - | 1e-171 | 85.27% (353) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2832c | ugpC | 8e-85 | 49.03% (361) | sn-glycerol-3-phosphate transport ATP-binding protein ABC |
| M. leprae Br4923 | MLBr_01424 | - | 4e-85 | 47.08% (359) | putative binding-protein-dependent transport protein |
| M. abscessus ATCC 19977 | MAB_1375 | - | 6e-83 | 44.42% (385) | sugar ABC transporter, ATP-binding protein SugC |
| M. marinum M | MMAR_1901 | - | 2e-84 | 49.31% (363) | ABC-type sugar transport protein, ATPase component |
| M. avium 104 | MAV_2479 | - | 1e-85 | 49.14% (350) | glycerol-phosphate porter |
| M. smegmatis MC2 155 | MSMEG_3108 | - | 1e-132 | 71.11% (360) | ABC transporter, ATPase subunit |
| M. thermoresistible (build 8) | TH_3215 | - | 1e-80 | 47.03% (370) | PUTATIVE ABC transporter ATP-binding protein |
| M. ulcerans Agy99 | MUL_2252 | - | 9e-84 | 49.71% (350) | sugar-transport ATP-binding protein ABC transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2479|M.avium_104 MSMASVTFQQATRRYPGADRPALDNLNLVVGDGEFVVLVGPSGCGKTTSL
MUL_2252|M.ulcerans_Agy99 --MASVSFEGATRRYPGADRPAVDSLDLVVDDGEFVVLVGPSGCGKTTSL
MLBr_01424|M.leprae_Br4923 --MASVTFEQATRQFPDTDRPALDRLDLDVDDGEFVVVVGPSGCGKTTSL
TH_3215|M.thermoresistible__bu --MATITYRNASCIYEGSDTFAVNSLNLEIEDGEFVVLVGPSGSGKSTAL
Mb2856c|M.bovis_AF2122/97 --MANVQYSAVTQRYPGADAPTVDNLDLDIADGEFLVLVGPSGCGKSTTL
Rv2832c|M.tuberculosis_H37Rv --MANVQYSAVTQRYPGADAPTVDNLDLDIADGEFLVLVGPSGCGKSTTL
MMAR_1901|M.marinum_M --MAKVQYSGVTYRYPGSGAPAVNNLDLEIADGEFLVLVGPSGCGKSTIL
MAB_1375|M.abscessus_ATCC_1997 --MAEIVLNQVSKTYTDG-SAAVRDVSLNIADGEFIILVGPSGCGKSTTL
Mvan_2621|M.vanbaalenii_PYR-1 --MATVRFSGVNKAYGTT--SVVSDLDLELPDGSFTVLVGPSGCGKSTSL
Mflv_3778|M.gilvum_PYR-GCK --MATVRFSGVTKAYGST--SVVSDLDLELPDGSLSVLVGPSGCGKSTTL
MSMEG_3108|M.smegmatis_MC2_155 --MASVTFSKVEKSYGAV--TVVKDLDLELADGSLTVLVGPSGCGKTTSL
** : . : .: :.* : **.: ::*****.**:* *
MAV_2479|M.avium_104 RMVAGLETVDSGRILIGDRDVTNVDPKQRDVAMVFQNYALYPHMTVAQNM
MUL_2252|M.ulcerans_Agy99 RMLAGLEKVDAGRIRIAERDVTNVDPKSRDVAMVFQNYALYPHMTVAQNM
MLBr_01424|M.leprae_Br4923 RMVAGLETLDSGCIRIGDRDVTHVDPKDRDVAMVFQNYALYPHMTVAQNL
TH_3215|M.thermoresistible__bu RMLAGLEDIDDGDIEIGGRNMRGVPSKDRDIAMVFQNYALYPNKTVAENM
Mb2856c|M.bovis_AF2122/97 RVLAGLEPIESGRISIGDVDVTHLPPRARDVAMVFQNYALYPNMTVAANM
Rv2832c|M.tuberculosis_H37Rv RVLAGLEPIESGRISIGDVDVTHLPPRARDVAMVFQNYALYPNMTVAANM
MMAR_1901|M.marinum_M RVLAGLESVESGRITIGDTDVTDLPPRARDVAMVFQNYALYPNMTVAQNM
MAB_1375|M.abscessus_ATCC_1997 NMIAGLEDISSGELTIAGERVNEKAPKDRDIAMVFQSYALYPHMTVRQNI
Mvan_2621|M.vanbaalenii_PYR-1 RMLAGLETVTSGSITIGARDVTHLQPRDRDIAMVFQNYALYPHLTVAENI
Mflv_3778|M.gilvum_PYR-GCK RMLAGLETVTSGTITIGDRDVTHLQPRDRDIAMVFQNYALYPHLTVAENI
MSMEG_3108|M.smegmatis_MC2_155 RMLAGLEPVTSGTIHIGDRDVTRLEPRDRDIAMVFQNYALYPHLTVRENI
.::**** : * : *. : .: **:*****.*****: ** *:
MAV_2479|M.avium_104 GFAMKIAKTPKAQIRERVLDAAKLLDLQPYLDRKPKDLSGGQRQRVAMGR
MUL_2252|M.ulcerans_Agy99 GFALKVAKTPKAEIRDRVLQAAKLLDLEAYLDRKPKDLSGGQRQRVAMGR
MLBr_01424|M.leprae_Br4923 GFALKISKISKAEIHDRILVVAKLLDLQPYLDRKPKDLSGGQRQRVAMGR
TH_3215|M.thermoresistible__bu GFALKLRGVAASERRRKVEEAAKLLDLTEFLDRKPAKLSGGQRQRVAMGR
Mb2856c|M.bovis_AF2122/97 GFALRNAGMSRADTRRRVLEVADMLELTDLLDRKPAKLSGGQRQRVAMGR
Rv2832c|M.tuberculosis_H37Rv GFALRNAGMSRADTRRRVLEVADMLELTDLLDRKPAKLSGGQRQRVAMGR
MMAR_1901|M.marinum_M GFALRNAGMSRADTRQRVLEVASMLELTELLDRKPSKLSGGQRQRVAMGR
MAB_1375|M.abscessus_ATCC_1997 AFPLTLAKMSKDDINAKVAEAAKILDLTDYLDRKPANLSGGQRQRVAMGR
Mvan_2621|M.vanbaalenii_PYR-1 AFPLRATKTPRREALTRAATIAESLGLAKLLDRKPKDLSGGQQQRVAIGR
Mflv_3778|M.gilvum_PYR-GCK AFPLRANKTPRREALARAATVAESLGLSALLGRKPKDLSGGQQQRVAIGR
MSMEG_3108|M.smegmatis_MC2_155 AFPLRATKTPRAEALKRADDIAASLGLGALVSRKPKDLSGGQQQRVAIGR
.*.: . : : * * * :.*** .*****:****:**
MAV_2479|M.avium_104 AIVRRPQVFLMDEPLSNLDAKLRVQTRNQIAALQRRLGTTTVYVTHDQVE
MUL_2252|M.ulcerans_Agy99 AIVRRPQVFLMDEPLSNLDTKLRVQTRNQIAGLQRQLGTTTVYVTHDQVE
MLBr_01424|M.leprae_Br4923 AIVRRPQVFLMDEPLSNLDAKLRAQTRNQIAELQCQLGTTTVYVTHDQVE
TH_3215|M.thermoresistible__bu AIVREPQVFCMDEPLSNLDAKLRVQTRTQIAALQRRLGTTTVYVTHDQVE
Mb2856c|M.bovis_AF2122/97 AIVRRPRVFCMDEPLSNLDAKLRVSTRSQISGLQRRLGTTTVYVTHDQVE
Rv2832c|M.tuberculosis_H37Rv AIVRRPRVFCMDEPLSNLDAKLRVSTRSQISGLQRRLGTTTVYVTHDQVE
MMAR_1901|M.marinum_M AIVRRPRVFCMDEPLSNLDAKLRVSTRSHISGLQRQLGTTTVYVTHDQVE
MAB_1375|M.abscessus_ATCC_1997 AIVRSPKAFLMDEPLSNLDAKLRVQMRTEIARLQKRLGTTTVYVTHDQTE
Mvan_2621|M.vanbaalenii_PYR-1 AIIREPSVFLFDEPLSNLDAKLRVETRTELLQIQRRLGITSVYVTHDQEE
Mflv_3778|M.gilvum_PYR-GCK AIIREPSVFLFDEPLSNLDAKLRVETRTELAQIQRRLGITSVYVTHDQEE
MSMEG_3108|M.smegmatis_MC2_155 AIIREPAVFLFDEPLSNLDAKLRVETRTELLRLQRRLGITSLYVTHDQEE
**:* * .* :********:***.. *..: :* :** *::****** *
MAV_2479|M.avium_104 AMTMGDRVAVLRDGVLQQFAPPRELYRNPSNVFVAGFIGSPAMNLFTLPV
MUL_2252|M.ulcerans_Agy99 AMTMGDRVAVLCDGVLQQCAAPRELYRRPDNVFVAGFIGSPAMNMFILPI
MLBr_01424|M.leprae_Br4923 AMTMGDRVAVLCYGVLQQFATPRELYHKPENVFVAGFIGSPGMNLVTLSI
TH_3215|M.thermoresistible__bu AMTMGDRVAVLKHGRLQQFASPGDLYHRPANAFVAGFIGSPAMNLFNAQL
Mb2856c|M.bovis_AF2122/97 AMTMGDRVAVLKDGVLQQVDTPRALYDDPVNTFVATFIGAPAMNLIDAAV
Rv2832c|M.tuberculosis_H37Rv AMTMGDRVAVLKDGVLQQVDTPRALYDDPVNTFVATFIGAPAMNLIDAAV
MMAR_1901|M.marinum_M AMTMGHRVAVLKDGVLQQVDTPRELYDNPVNTFVATFIGAPAMNLIEAPV
MAB_1375|M.abscessus_ATCC_1997 AMTLGDRVVVLRAGKVQQVGAPQELYDTPANLFVAGFIGSPSMNFFPATL
Mvan_2621|M.vanbaalenii_PYR-1 AMTLSDRMVVMRDGRIAQQGTPQEVYARPADTFVAAFVGSPKMNLIDGAV
Mflv_3778|M.gilvum_PYR-GCK AMTLSDRMIVMRDGKIAQQGAPQDVYARPADTFVAAFVGSPKMNLLEGTL
MSMEG_3108|M.smegmatis_MC2_155 AMTLSDRIVVMRDGQIAQAGPPEEVYRRPADTFVATFVGSPKMNLVDGAV
***:..*: *: * : * .* :* * : *** *:*:* **:. :
MAV_2479|M.avium_104 VDSAVSLG-DWPIALPREIAAAASE------VVVGVRPEHFELGGLG---
MUL_2252|M.ulcerans_Agy99 VDSSVLLG-DWLIQLPREVTVPAPE------VVVGVRPEHFEVGNLG---
MLBr_01424|M.leprae_Br4923 VDSSVLLG-DWPIRIPREIASAASE------VIIGVRPEHFELGSLG---
TH_3215|M.thermoresistible__bu VPEGVQIG-DTVLELERAQLTALHEAKLD-TVTVGLRPEHLELSDAGG--
Mb2856c|M.bovis_AF2122/97 AHGVVRAP-DLAIPVPDPAAER---------VLVGVRPESWDVASIGTPG
Rv2832c|M.tuberculosis_H37Rv AHGVVRAP-DLAIPVPDPAAER---------VLVGVRPESWDVASIGTPG
MMAR_1901|M.marinum_M ADGVARLS-GLVIPVPRGAADR---------VLIGVRPESWDVVGGDAAA
MAB_1375|M.abscessus_ATCC_1997 TDVGVQLP-FGEVTLDAGLYAGITARKPSGDVIVGIRPEQFEDAALVDTY
Mvan_2621|M.vanbaalenii_PYR-1 SGTTFTVGDGFALTVDQTAAGGP--------VTLGVRPDDLLP-----TV
Mflv_3778|M.gilvum_PYR-GCK TGGTFTLANGFALPIDEGATDGP--------LTLGVRPDDLLP-----TV
MSMEG_3108|M.smegmatis_MC2_155 SGGELRTESGLRIRVGG-PDAAA--------VTVGVRPDDLTLRPVQTTA
: : : :*:**:
MAV_2479|M.avium_104 -------VEMEVDVVEELGADAYLYGR-------------ITGSGKVIDA
MUL_2252|M.ulcerans_Agy99 -------VEMEIDVVEELGADAYLYGR-------------ISNGGTMIDQ
MLBr_01424|M.leprae_Br4923 -------VEVEIDMVEELGADAYLYGR-------------IAGASKVTDQ
TH_3215|M.thermoresistible__bu -------VEVVVDLVEDLGSEAYLYTH-------------TGSG-----V
Mb2856c|M.bovis_AF2122/97 S------LTVHVELVEELGFESFVYATPV-----------DQRGWSSRAP
Rv2832c|M.tuberculosis_H37Rv S------LTVHVELVEELGFESFVYATPV-----------DQRGWSSRAP
MMAR_1901|M.marinum_M A------LGVRVEQVEELGFESFIYATPV-----------AQDGWSSRTR
MAB_1375|M.abscessus_ATCC_1997 KRITGLTLTVNADVVESLGSDKYVHFTTEGGAAHSDELTELAQESEVAEN
Mvan_2621|M.vanbaalenii_PYR-1 SDG---DGAARVILIEHLGPRAIVTID-----------------ARGTEL
Mflv_3778|M.gilvum_PYR-GCK GAA---DAPARVALIEHLGPRAIVTVD-----------------ARGTEL
MSMEG_3108|M.smegmatis_MC2_155 TTA---SAAPTVELVELLGPRAIVTVR-----------------SGELRL
:* ** :
MAV_2479|M.avium_104 PIVARVDGRNPPEKGSRVRLHP-APGHLHFFGRN-GQRIGVRGSW-
MUL_2252|M.ulcerans_Agy99 SVVARADGSNPPERGSRVRLYP-QPAQLHFFTVD-GRRIA------
MLBr_01424|M.leprae_Br4923 LVVARVDGRNPPAKGSRVRLYT-EPGNVHFFGVD-GHRIS------
TH_3215|M.thermoresistible__bu DLVARCLDRVPAKLADTVRLRKRTDGVVHLFHPDTGERVGE-----
Mb2856c|M.bovis_AF2122/97 RIVFRTDRRTAVRVGESLAIVP-HSQEVRLFNSRTETRLR------
Rv2832c|M.tuberculosis_H37Rv RIVFRTDRRTAVRVGESLAIVP-HSQEVRLFNSRTETRLR------
MMAR_1901|M.marinum_M RIVIRSDRHTTVGAGDSLSIAP-NPQEVCFFDSRTESRIR------
MAB_1375|M.abscessus_ATCC_1997 EFVARLSAASKVAEGQPIELII-DTGKLVIFDAESGENLSLAATAE
Mvan_2621|M.vanbaalenii_PYR-1 TSVVETSRLSGITEGTPVDLAVRPGA-THFFDPATGSRLSG-----
Mflv_3778|M.gilvum_PYR-GCK TSVVDTARLSGITEGTGVELAVRQGA-THLFDTTTGRRIAGETR--
MSMEG_3108|M.smegmatis_MC2_155 TSVVDAPSLSEIPTGTAVELSARD---VHRFDIATGTRLPD-----
* . : : * .: